#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q16666-2 uniprotkb:P16104 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BSC4 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-7001376|uniprotkb:Q53RC9|uniprotkb:Q9H855|uniprotkb:Q96TA5|uniprotkb:Q9H7Y7|uniprotkb:A8K3R5|intact:MINT-3060916|uniprotkb:B4DLV0|ensembl:ENSP00000371101 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nol10_human(display_long)|uniprotkb:NOL10(gene name)|psi-mi:NOL10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_079170.2|refseq:NP_001248323.1|refseq:NP_001248321.1|ensembl:ENSG00000115761(gene)|ensembl:ENST00000381685(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012580(NUC153)|interpro:IPR036322|interpro:IPR040382|mint:Q9BSC4 - isoform-comment:Major isoform. comment:mint figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:PiblslntTRSvRQnk82fSgtVJbXE9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NV06 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-7402939|uniprotkb:Q3MII9|uniprotkb:Q96JY7|uniprotkb:Q9NZX3|intact:MINT-4994304|uniprotkb:Q8NCH8|uniprotkb:Q8TC51|ensembl:ENSP00000484962 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:dca13_human(display_long)|uniprotkb:HSPC064(orf name)|uniprotkb:DCAF13(gene name)|psi-mi:DCAF13(display_short)|uniprotkb:WDSOF1(gene name synonym)|uniprotkb:WD repeat and SOF domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_056235.4|ensembl:ENSG00000164934(gene)|ensembl:ENST00000612750(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030054"(cell junction)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9NV06|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-8951664 - isoform-comment:Major isoform. comment:mint|comment:homomint|function:Possible role in ribosomal RNA processing figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:Ep2z6/V6/US0sXDqjqjpVqmf/zM9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P56182 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9UBB4 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-702390|uniprotkb:O14998|uniprotkb:O15009|uniprotkb:Q6I9X4|uniprotkb:A6NLC4|uniprotkb:B4DG05|ensembl:ENSP00000252934 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:atx10_human(display_long)|uniprotkb:Spinocerebellar ataxia type 10 protein(gene name synonym)|uniprotkb:Brain protein E46 homolog(gene name synonym)|uniprotkb:ATXN10(gene name)|psi-mi:ATXN10(display_short)|uniprotkb:SCA10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001161093.1|refseq:NP_037368.1|ensembl:ENSG00000130638(gene)|ensembl:ENST00000252934(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:Q9UBB4 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:kQ+1aM5ZEzIlpH2lKWFGVSrCDww9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P42694 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1210654|uniprotkb:I6L9H4|ensembl:ENSP00000351524 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:helz_human(display_long)|uniprotkb:HELZ(gene name)|psi-mi:HELZ(display_short)|uniprotkb:KIAA0054(gene name synonym)|uniprotkb:DRHC(gene name synonym)|uniprotkb:Down-regulated in human cancers protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_055692.2|ensembl:ENSG00000198265(gene)|ensembl:ENST00000358691(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|dip:DIP-39352N|interpro:IPR027417|interpro:IPR036855|interpro:IPR041677|interpro:IPR041679 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:q+2P+W7RDRl2CyPhdEsvONGaM0U9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14694 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2510389|uniprotkb:B4DS84|uniprotkb:B2RDJ8|uniprotkb:Q9BWG7|uniprotkb:Q9NSL7|ensembl:ENSP00000219473 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ubp10_human(display_long)|uniprotkb:USP10(gene name)|psi-mi:USP10(display_short)|uniprotkb:KIAA0190(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005144.2|ensembl:ENSP00000219473|ensembl:ENST00000570191|ensembl:ENSP00000457411|refseq:NP_001259004.1|ensembl:ENSG00000103194(gene)|ensembl:ENST00000219473(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR018200|interpro:IPR028767|interpro:IPR028889|interpro:IPR038765|mint:Q14694|reactome:R-HSA-5656169|reactome:R-HSA-5689880|go:"GO:0005737"(cytoplasm) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:W34ZdOIilLOVI8SXqCH3rOmmloo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14137 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1050828|uniprotkb:Q969Z6|uniprotkb:Q96IS8|uniprotkb:Q9BSA7|uniprotkb:Q9BVM0|ensembl:ENSP00000455106|ensembl:ENSP00000495401|uniprotkb:Q96Q25 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:bop1_human(display_long)|uniprotkb:Block of proliferation 1 protein(gene name synonym)|uniprotkb:BOP1(gene name)|psi-mi:BOP1(display_short)|uniprotkb:KIAA0124(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_056016.1|ensembl:ENSG00000261236(gene)|ensembl:ENSG00000285301(gene)|ensembl:ENST00000569669(transcript)|ensembl:ENST00000642409(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR012953(BOP1, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028598|interpro:IPR036322|mint:Q14137|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:g2CwsRotXBvjvr+rSZSA0mKrVCY9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9P258 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-352547|uniprotkb:Q8IVL9|uniprotkb:Q9BSN6|uniprotkb:Q9NPV8|ensembl:ENSP00000364582|ensembl:ENSP00000364585|ensembl:ENSP00000486099|ensembl:ENSP00000486447 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rcc2_human(display_long)|uniprotkb:RCC2(gene name)|psi-mi:RCC2(display_short)|uniprotkb:KIAA1470(gene name synonym)|uniprotkb:TD60(gene name synonym)|uniprotkb:Telophase disk protein of 60 kDa(gene name synonym)|uniprotkb:RCC1-like protein TD-60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001129676.1|refseq:NP_061185.1|ensembl:ENSG00000179051(gene)|ensembl:ENSG00000281540(gene)|ensembl:ENST00000375433(transcript)|ensembl:ENST00000375436(transcript)|ensembl:ENST00000628984(transcript)|ensembl:ENST00000631021(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051301"(cell division)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072356"(chromosome passenger complex localization to kinetochore)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR028641|mint:Q9P258|rcsb pdb:5GWN|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:z9+0avftBLs4Q3ODFHLEmJtd57A9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8TDN6 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_060791.3|ensembl:ENSG00000113460(gene)|ensembl:ENST00000336767(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P63244 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P53621 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O60264 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q08J23 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8NI36 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2512413|ensembl:ENSP00000423067|ensembl:ENSP00000479950|uniprotkb:A2RUS4|uniprotkb:Q8N1Q2|uniprotkb:Q68E02 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:wdr36_human(display_long)|uniprotkb:WDR36(gene name)|psi-mi:WDR36(display_short)|uniprotkb:T-cell activation WD repeat-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000134987(gene)|ensembl:ENST00000506538(transcript)|ensembl:ENST00000612402(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0007601"(visual perception)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|go:"GO:0050896"(response to stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR007319(Small-subunit processome, Utp21)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|refseq:NP_644810.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:97Qc0ehUPTjCBcn3gjr0FY8Nnus9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NQ55 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1048540|uniprotkb:Q9BW97|uniprotkb:Q9H170|uniprotkb:C9J3F9|ensembl:ENSP00000253107 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ssf1_human(display_long)|uniprotkb:Peter Pan homolog(gene name synonym)|uniprotkb:PPAN(gene name)|psi-mi:PPAN(display_short)|uniprotkb:SSF1(gene name synonym)|uniprotkb:BXDC3(gene name synonym)|uniprotkb:Brix domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001035754.1|refseq:NP_064615.3|ensembl:ENSG00000130810(gene)|ensembl:ENST00000253107(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR007109(Brix)|mint:Q9NQ55 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:wIgMQj/xJrj5eExsyZD6BeamQOQ9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q13283 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q13206 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2514399|ensembl:ENSP00000314348|uniprotkb:Q5BJD8|uniprotkb:B2RCQ3 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ddx10_human(display_long)|uniprotkb:DDX10(gene name)|psi-mi:DDX10(display_short)|uniprotkb:DEAD box protein 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000178105(gene)|ensembl:ENST00000322536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0097065"(anterior head development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|mint:Q13206|rcsb pdb:2PL3|refseq:NP_004389.2 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:MMAbABrYQHlYDyPsagT7oY92Z3M9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q15397 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-725523|uniprotkb:Q547G7|uniprotkb:Q5SZY9|uniprotkb:Q6IB47|uniprotkb:Q96B27|uniprotkb:Q96L78|uniprotkb:Q96L79|uniprotkb:Q96L80|uniprotkb:A8K804|ensembl:ENSP00000380982 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pum3_human(display_long)|uniprotkb:PUM3(gene name)|psi-mi:PUM3(display_short)|uniprotkb:cPERP-C(gene name synonym)|uniprotkb:HBV X-transactivated gene 5 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 5(gene name synonym)|uniprotkb:KIAA0020(gene name synonym)|uniprotkb:Minor histocompatibility antigen HA-8(gene name synonym)|uniprotkb:PUF-A(gene name synonym)|uniprotkb:XTP5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_055693.4|ensembl:ENSG00000080608(gene)|ensembl:ENST00000397885(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006417"(regulation of translation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012959(CPL)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR040059|mint:Q15397|rcsb pdb:4WZR|rcsb pdb:4WZW - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:CjfVWg+3P3ai0EiHgeH8usbvgxg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8IZL8 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:iu03DsintVoo3gWzZX14SlHE0ao9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q93009 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q92615 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_055970.1|ensembl:ENSP00000326128|ensembl:ENSG00000107929(gene)|ensembl:ENST00000316157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3PTH - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O00541 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1053271|uniprotkb:Q6IC29|ensembl:ENSP00000346725 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pesc_human(display_long)|uniprotkb:PES1(gene name)|psi-mi:PES1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001230154.1|refseq:NP_055118.1|ensembl:ENSG00000100029(gene)|ensembl:ENST00000354694(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:2EP8|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:Nq1SJ37kJfe+vF9zmNASz1gnbfY9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9UQ35 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1050142|uniprotkb:A6NKB9|uniprotkb:Q9UHA8|uniprotkb:Q9UQ36|uniprotkb:Q9UQ37|uniprotkb:Q9UQ38|uniprotkb:Q9UQ40|uniprotkb:O15038|uniprotkb:O94803|uniprotkb:Q6NSL3|uniprotkb:Q6PIM3|uniprotkb:Q6PK40|uniprotkb:Q8IW17|uniprotkb:Q96GY7|uniprotkb:Q9P0G1|uniprotkb:D3DU97|ensembl:ENSP00000301740 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:srrm2_human(display_long)|uniprotkb:Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa(gene name synonym)|uniprotkb:Splicing coactivator subunit SRm300(gene name synonym)|uniprotkb:300 kDa nuclear matrix antigen(gene name synonym)|uniprotkb:SRRM2(gene name)|psi-mi:SRRM2(display_short)|uniprotkb:KIAA0324(gene name synonym)|uniprotkb:SRL300(gene name synonym)|uniprotkb:SRM300(gene name synonym)|uniprotkb:HSPC075(orf name)|uniprotkb:Tax-responsive enhancer element-binding protein 803(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_057417.3|ensembl:ENSG00000167978(gene)|ensembl:ENST00000301740(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|mint:Q9UQ35|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|reactome:R-HSA-72163 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:3yyPAOaCzKSCEg5guJSbq0MWrHI9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NX58 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-713507|uniprotkb:Q6FI78|uniprotkb:Q9NYS1|ensembl:ENSP00000345917|ensembl:ENSP00000397367|uniprotkb:D3DVS4 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:lyar_human(display_long)|uniprotkb:LYAR(gene name)|psi-mi:LYAR(display_short)|uniprotkb:PNAS-5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000145220(gene)|ensembl:ENST00000343470(transcript)|ensembl:ENST00000452476(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|interpro:IPR041010|mint:Q9NX58|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZVH|refseq:NP_001139197.1|refseq:NP_060286.1|refseq:XP_011511807.1|refseq:XP_011511808.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:AJ+5B1LahcUlSWQehJ2vxY+8pwY9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14444 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|intact:EBI-3449178|uniprotkb:D3DR06|ensembl:ENSP00000340329|ensembl:ENSP00000434150 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005889.3|refseq:NP_976240.1|ensembl:ENSG00000135387(gene)|ensembl:ENST00000341394(transcript)|ensembl:ENST00000532820(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0045202"(synapse)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|refseq:XP_016873238.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BVP2 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENST00000394799|ensembl:ENSP00000378278|ensembl:ENSP00000395772|refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938(gene)|ensembl:ENST00000418458(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030496"(midbody)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|mint:Q9BVP2|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9H7B2 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1051960|uniprotkb:Q8N4A1|uniprotkb:Q5VXN1|ensembl:ENSP00000402338 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rpf2_human(display_long)|uniprotkb:RPF2(gene name)|psi-mi:RPF2(display_short)|uniprotkb:BXDC1(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:Brix domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_115570.1|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007109(Brix)|interpro:IPR039770|mint:Q9H7B2|ensembl:ENSG00000197498(gene)|ensembl:ENST00000441448(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:CXU4CHQmcrISLS8GDIwEMGhiaQI9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NWH9 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2814558|uniprotkb:A8K5V8|uniprotkb:Q6ZNF2|uniprotkb:B2RTX3|uniprotkb:Q9H7C3|uniprotkb:Q658J7|uniprotkb:Q52MB3|uniprotkb:Q9H8U9|uniprotkb:Q86TK6|uniprotkb:Q2VPK7|ensembl:ENSP00000369887 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:sltm_human(display_long)|uniprotkb:SLTM(gene name)|psi-mi:SLTM(display_short)|uniprotkb:MET(gene name synonym)|uniprotkb:Modulator of estrogen-induced transcription(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:XP_006720753.1|refseq:NP_079031.2|refseq:NP_001013865.1|refseq:XP_016878069.1|ensembl:ENSG00000137776(gene)|ensembl:ENST00000380516(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034780|interpro:IPR035979|interpro:IPR036361|mint:Q9NWH9 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:/B0FdPpFi/TvMq9aGjuLOQ3zIuo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P10412 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-358163|uniprotkb:Q4VB25|ensembl:ENSP00000307705 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:h14_human(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1F4(gene name synonym)|uniprotkb:HIST1H1E(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005312.1|rcsb pdb:6H8P|rcsb pdb:7K5Y|rcsb pdb:7K63|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10412|rcsb pdb:3TZD|rcsb pdb:5JJZ|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000168298(gene)|ensembl:ENST00000304218(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:yT8wBbspLLR8G3DrgpFeWEOPgac9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8N163 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14692 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2513630|ensembl:ENSP00000363642|uniprotkb:Q86XJ9|uniprotkb:Q5QPT5 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:bms1_human(display_long)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)|uniprotkb:BMS1L(gene name synonym)|uniprotkb:KIAA0187(gene name synonym)|uniprotkb:Ribosome assembly protein BMS1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000165733(gene)|ensembl:ENST00000374518(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0030686"(90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|mint:Q14692|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|refseq:XP_011538704.1|refseq:NP_055568.3|refseq:XP_005271903.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:9sd7sK6/Ue4DgLRT+j9Iw0+8om09606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9Y4W2 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O75844 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1056377|uniprotkb:Q8NDZ8|uniprotkb:Q9UBQ2|uniprotkb:B3KQI7|uniprotkb:D3DPU7|ensembl:ENSP00000361845 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:face1_human(display_long)|uniprotkb:ZMPSTE24(gene name)|psi-mi:ZMPSTE24(display_short)|uniprotkb:FACE1(gene name synonym)|uniprotkb:STE24(gene name synonym)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:Farnesylated proteins-converting enzyme 1(gene name synonym)|uniprotkb:Zinc metalloproteinase Ste24 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005848.2|ensembl:ENSG00000084073(gene)|ensembl:ENST00000372759(transcript)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030282"(bone mineralization)|go:"GO:0030327"(prenylated protein catabolic process)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043979"(histone H2B-K5 acetylation)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048538"(thymus development)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0050905"(neuromuscular process)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070302"(regulation of stress-activated protein kinase signaling cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:1903025"(regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1903463"(regulation of mitotic cell cycle DNA replication)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990164"(histone H2A phosphorylation)|go:"GO:2000618"(regulation of histone H4-K16 acetylation)|go:"GO:2000730"(regulation of termination of RNA polymerase I transcription)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|rcsb pdb:2YPT|rcsb pdb:4AW6|rcsb pdb:5SYT|rcsb pdb:6BH8|dip:DIP-39641N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:OPwBYiVhnltoUrmk2Jtj07QDSCg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BRT6 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-741396|ensembl:ENSP00000266604|ensembl:ENSP00000437372|uniprotkb:Q3B766 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:llph_human(display_long)|uniprotkb:LLPH(gene name)|psi-mi:LLPH(display_short)|uniprotkb:C12orf31(gene name synonym)|uniprotkb:Protein LAPS18-like(gene name synonym)|uniprotkb:cPERP-G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_115714.1|ensembl:ENSG00000139233(gene)|ensembl:ENST00000266604(transcript)|ensembl:ENST00000446587(transcript)|go:"GO:0001099"(basal RNA polymerase II transcription machinery binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0097484"(dendrite extension)|interpro:IPR018784|rcsb pdb:6LSS|rcsb pdb:6LU8 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:VeZ4vf0MCcXIdjewPonPDz1vV709606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NW13 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2878099|ensembl:ENSP00000223073|uniprotkb:Q96CV3|uniprotkb:A4D100|uniprotkb:Q53H65|uniprotkb:B4DU52|uniprotkb:E9PDD9 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rbm28_human(display_long)|uniprotkb:RBM28(gene name)|psi-mi:RBM28(display_short)|uniprotkb:RNA-binding motif protein 28(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9NW13|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000106344(gene)|ensembl:ENST00000223073(transcript)|refseq:NP_001159607.1|refseq:NP_060547.2 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:yIPQX+d5YQpq3gpdtBilOXJcUsg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q15050 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-749186|uniprotkb:Q9BUX8|ensembl:ENSP00000322396 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rrs1_human(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:KIAA0112(gene name synonym)|uniprotkb:RRR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_055984.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|mint:Q15050|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000179041(gene)|ensembl:ENST00000320270(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:0Nm9UoIGLBiqOGl0E2BA0S5EXIU9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8IWA0 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2515097|ensembl:ENSP00000314193|uniprotkb:Q9UIX2|uniprotkb:Q9H9U5|uniprotkb:Q96J10|uniprotkb:Q9H8U8|uniprotkb:Q9H9V8 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:wdr75_human(display_long)|uniprotkb:WDR75(gene name)|psi-mi:WDR75(display_short)|uniprotkb:UTP17(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 17 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000115368(gene)|ensembl:ENST00000314761(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_115544.1|refseq:NP_001290025.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:qAYPzmryYALOzvea97t1q/NCsVs9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BXY0 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-5280229|uniprotkb:B2RB44|uniprotkb:Q5U5T1|uniprotkb:Q86UC4|uniprotkb:Q96SY6|ensembl:ENSP00000353246 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:mak16_human(display_long)|uniprotkb:MAK16(gene name)|psi-mi:MAK16(display_short)|uniprotkb:RBM13(gene name synonym)|uniprotkb:NNP78(gene name synonym)|uniprotkb:Protein RBM13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_115898.2|ensembl:ENSG00000198042(gene)|ensembl:ENST00000360128(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR006958(Mak16 protein)|interpro:IPR029004|mint:Q9BXY0 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:Zedk3AV8WcIUeBxPWbFlL6HztIA9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q86TG7 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2858265|uniprotkb:Q9UPV1|uniprotkb:Q96A68 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:peg10_human(display_long)|uniprotkb:PEG10(gene name)|psi-mi:PEG10(display_short)|uniprotkb:EDR(gene name synonym)|uniprotkb:KIAA1051(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:MART2(gene name synonym)|uniprotkb:MEF3L1(gene name synonym)|uniprotkb:RGAG3(gene name synonym)|uniprotkb:Embryonal carcinoma differentiation-regulated protein(gene name synonym)|uniprotkb:Mammalian retrotransposon-derived protein 2(gene name synonym)|uniprotkb:Myelin expression factor 3-like protein 1(gene name synonym)|uniprotkb:Paternally expressed gene 10 protein(gene name synonym)|uniprotkb:Retrotransposon gag domain-containing protein 3(gene name synonym)|uniprotkb:Retrotransposon-derived gag-like polyprotein(gene name synonym)|uniprotkb:Ty3/Gypsy-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) interpro:IPR032549|interpro:IPR032567|refseq:NP_001035242.1|refseq:NP_001171890.1|refseq:NP_001171891.1|refseq:NP_055883.2|interpro:IPR021109|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|interpro:IPR043128|interpro:IPR043502 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:wkCBsH9/PsFMwJFu/qOwZcn63D49606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P20290 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1054687|uniprotkb:Q13893|uniprotkb:Q76M56|uniprotkb:A8K510|ensembl:ENSP00000369965 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:btf3_human(display_long)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001032726.1|refseq:NP_001198.2|ensembl:ENSG00000145741(gene)|ensembl:ENST00000380591(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|mint:P20290|rcsb pdb:3LKX|rcsb pdb:3MCB - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:TU7PtK2KVrzmdfaTdWcHloiRZYg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9UKK9 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-721623|uniprotkb:Q6IAG0|uniprotkb:Q9UH49|uniprotkb:A8K516|ensembl:ENSP00000419628|ensembl:ENSP00000445116 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nudt5_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 5(gene name synonym)|uniprotkb:YSA1H(gene name synonym)|uniprotkb:NUDT5(gene name)|psi-mi:NUDT5(display_short)|uniprotkb:HSPC115(orf name)|uniprotkb:8-oxo-dGDP phosphatase(gene name synonym)|uniprotkb:NUDIX5(gene name synonym)|uniprotkb:Nuclear ATP-synthesis protein NUDIX5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_054861.2|ensembl:ENSG00000165609(gene)|ensembl:ENST00000491614(transcript)|ensembl:ENST00000537776(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0009191"(ribonucleoside diphosphate catabolic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019144"(ADP-sugar diphosphatase activity)|go:"GO:0019303"(D-ribose catabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0030515"(snoRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|rcsb pdb:2DSB|rcsb pdb:2DSC|rcsb pdb:2DSD|rcsb pdb:3AC9|rcsb pdb:3ACA|rcsb pdb:3BM4|rcsb pdb:3L85|rcsb pdb:5NQR|rcsb pdb:5NWH|rcsb pdb:5QJ4|rcsb pdb:5QJ5|rcsb pdb:5QJ6|rcsb pdb:5QJ7|rcsb pdb:5QJ8|rcsb pdb:5QJ9|rcsb pdb:5QJA|rcsb pdb:5QJB|rcsb pdb:5QJC|rcsb pdb:5QJD|rcsb pdb:5QJE|rcsb pdb:5QJF|rcsb pdb:5QJG|rcsb pdb:5QJH|rcsb pdb:5QJI|rcsb pdb:5QJJ|rcsb pdb:5QJK|rcsb pdb:5QJL|rcsb pdb:5QJM|rcsb pdb:5QJN|rcsb pdb:5QJO|rcsb pdb:5QJP|rcsb pdb:5QJQ|rcsb pdb:5QJR|rcsb pdb:5QJS|rcsb pdb:5QJT|rcsb pdb:5QJU|rcsb pdb:5QJV|rcsb pdb:5QJW|rcsb pdb:5QJX|rcsb pdb:5QJY|rcsb pdb:5QJZ|rcsb pdb:5QK0|rcsb pdb:5QK1|rcsb pdb:5QK2|rcsb pdb:5QK3|rcsb pdb:5QK4|rcsb pdb:5QK5|rcsb pdb:5QKB|rcsb pdb:5QTL|rcsb pdb:5QTM|rcsb pdb:5QTN|rcsb pdb:5QTO|rcsb pdb:5QTP|rcsb pdb:5QTQ|rcsb pdb:5QTR|rcsb pdb:5QTS|rcsb pdb:6GRU|reactome:R-HSA-2393930|rcsb pdb:5QK6|rcsb pdb:5QK7|rcsb pdb:5QK8|rcsb pdb:5QK9|rcsb pdb:5QKA - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:jeBjAoLC9hGn34DKTP5QehZeZwM9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q99575 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8WWQ0 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-722984|uniprotkb:A7J992|ensembl:ENSP00000275034|uniprotkb:Q05CQ9|uniprotkb:Q5VVH4|uniprotkb:Q66I29|uniprotkb:Q69YV1|uniprotkb:Q8NBZ5|uniprotkb:Q96H52|uniprotkb:Q96ME2|uniprotkb:Q9H261|uniprotkb:B2RPK4 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:phip_human(display_long)|uniprotkb:IRS-1 PH domain-binding protein(gene name synonym)|uniprotkb:WD repeat-containing protein 11(gene name synonym)|uniprotkb:PHIP(gene name)|psi-mi:PHIP(display_short)|uniprotkb:WDR11(gene name synonym)|uniprotkb:DDB1- and CUL4-associated factor 14(gene name synonym)|uniprotkb:DCAF14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000146247(gene)|ensembl:ENST00000275034(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005158"(insulin receptor binding)|rcsb pdb:5ENC|rcsb pdb:5ENE|rcsb pdb:5ENF|rcsb pdb:5ENH|rcsb pdb:5ENI|rcsb pdb:5ENJ|rcsb pdb:5RJI|rcsb pdb:5RJJ|rcsb pdb:5RJK|rcsb pdb:5RJL|rcsb pdb:5RJM|rcsb pdb:5RJN|rcsb pdb:5RJO|rcsb pdb:5RJP|rcsb pdb:5RJQ|rcsb pdb:5RJR|rcsb pdb:5RJX|rcsb pdb:5RJY|rcsb pdb:5RJZ|rcsb pdb:5RK0|rcsb pdb:5RJS|rcsb pdb:5RJT|rcsb pdb:5RJU|rcsb pdb:5RJV|rcsb pdb:5RJW|rcsb pdb:5RK1|rcsb pdb:5RK2|rcsb pdb:5RK3|rcsb pdb:5RK4|rcsb pdb:5RK5|rcsb pdb:5RK6|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001487(Bromodomain)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018359|interpro:IPR019775|interpro:IPR028738|interpro:IPR036322|interpro:IPR036427|rcsb pdb:3MB3|rcsb pdb:5ENB|rcsb pdb:5RK7|rcsb pdb:5RK8|rcsb pdb:5RK9|rcsb pdb:5RKA|rcsb pdb:5RKB|rcsb pdb:5RKC|rcsb pdb:5RKD|rcsb pdb:5RKE|rcsb pdb:5RKF|rcsb pdb:5RKG|rcsb pdb:5RKH|rcsb pdb:5RKI|rcsb pdb:5RKJ|rcsb pdb:5RKK|rcsb pdb:5RKL|rcsb pdb:5RKM|rcsb pdb:5RKN|rcsb pdb:5RKO|rcsb pdb:5RKP|rcsb pdb:5RKQ|rcsb pdb:5RKR|rcsb pdb:5RKS|rcsb pdb:5RKT|rcsb pdb:5RKU|rcsb pdb:5RKV|rcsb pdb:5RKW|rcsb pdb:5RKX|rcsb pdb:5RKY|rcsb pdb:5S8C|rcsb pdb:5S8D|rcsb pdb:5S8E|rcsb pdb:5S8F|rcsb pdb:5S8G|rcsb pdb:5S8H|rcsb pdb:5S8I|rcsb pdb:5S8J|rcsb pdb:5S8K|rcsb pdb:5S8L|rcsb pdb:5S8M|rcsb pdb:5S8N|rcsb pdb:5S8O|rcsb pdb:5S8P|rcsb pdb:5S8Q|rcsb pdb:5S8R|rcsb pdb:5S8S|rcsb pdb:5S8T|rcsb pdb:5S8U|rcsb pdb:5S8V|rcsb pdb:5S8W|rcsb pdb:5S8X|rcsb pdb:5S8Y|rcsb pdb:5S8Z|rcsb pdb:5S90|rcsb pdb:5S91|rcsb pdb:5S92|rcsb pdb:5S93|rcsb pdb:5S94|rcsb pdb:5S95|rcsb pdb:5S96|rcsb pdb:5S97|rcsb pdb:5S98|rcsb pdb:5S99|rcsb pdb:5S9A|rcsb pdb:5S9B|rcsb pdb:5S9C|rcsb pdb:5S9D|rcsb pdb:5S9E|rcsb pdb:5S9F|rcsb pdb:5S9G|rcsb pdb:5S9H|rcsb pdb:5S9I|rcsb pdb:5S9J|rcsb pdb:7AV8|rcsb pdb:7AV9|rcsb pdb:7BBO|rcsb pdb:7BBP|reactome:R-HSA-9013418|refseq:NP_060404.4 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:TptYI8D8CdPa97zbqW3sjmFti289606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14690 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-300028|uniprotkb:Q9H4P1|ensembl:ENSP00000358812|uniprotkb:Q86VQ8|uniprotkb:Q5W093|uniprotkb:Q2TA92|uniprotkb:Q6P2J3 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rrp5_human(display_long)|uniprotkb:PDCD11(gene name)|psi-mi:PDCD11(display_short)|uniprotkb:KIAA0185(gene name synonym)|uniprotkb:Programmed cell death protein 11(gene name synonym)|uniprotkb:NF-kappa-B-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000148843(gene)|ensembl:ENST00000369797(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032040"(small-subunit processome)|interpro:IPR003029(S1, RNA binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008847(Suppressor of forked)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|mint:Q14690|rcsb pdb:1WI5|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0006397"(mRNA processing)|refseq:NP_055791.1|refseq:XP_011537841.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:G3h7KMQzbRdyetWmb3uVBqXJWu09606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8WTT2 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2512539|ensembl:ENSP00000360412|uniprotkb:Q9H9D8|uniprotkb:Q9H5M6 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:noc3l_human(display_long)|uniprotkb:NOC3L(gene name)|psi-mi:NOC3L(display_short)|uniprotkb:AD24(gene name synonym)|uniprotkb:C10orf117(gene name synonym)|uniprotkb:FAD24(gene name synonym)|uniprotkb:NOC3-like protein(gene name synonym)|uniprotkb:Nucleolar complex-associated protein 3-like protein(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045444"(fat cell differentiation)|interpro:IPR005612(CBF)|interpro:IPR011501(Nucleolar complex-associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016903(Nucleolar complex-associated protein 3)|mint:Q8WTT2|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000173145(gene)|ensembl:ENST00000371361(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|refseq:NP_071896.8 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:s78IiBuQQjc0emiM/UkEMhzThVc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q7Z417 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q13610 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1050630|uniprotkb:A8K3R6|ensembl:ENSP00000387365|uniprotkb:Q7Z3X9 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045(gene)|ensembl:ENST00000412830(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9GZR7 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BQ39 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q7Z2T5 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1237316|uniprotkb:Q5TEN0|uniprotkb:Q6ZMX0|uniprotkb:Q8IWH5|uniprotkb:Q8NC68|uniprotkb:Q9BZQ1|ensembl:ENSP00000356476 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:trm1l_human(display_long)|uniprotkb:TRMT1L(gene name)|psi-mi:TRMT1L(display_short)|uniprotkb:C1orf25(gene name synonym)|uniprotkb:MSTP070(orf name)|uniprotkb:TRM1L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001189352.1|refseq:NP_112196.3|ensembl:ENSG00000121486(gene)|ensembl:ENST00000367506(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002940"(tRNA N2-guanine methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0004809"("tRNA (guanine-N2-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0007610"(behavior)|go:"GO:0046872"(metal ion binding)|interpro:IPR002905(N2,N2-dimethylguanosine tRNA methyltransferase)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029063|interpro:IPR042296 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:dctCUlcYZCnaX72mW3b0n9JM5w89606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P13010 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q5SSJ5 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2880687|ensembl:ENSP00000312625|ensembl:ENSP00000403039|uniprotkb:Q5SWC6|uniprotkb:Q6PIM9|uniprotkb:B3KMZ8|uniprotkb:A8K5D7|uniprotkb:Q8NDF0|uniprotkb:Q05BI0|uniprotkb:B4E210|uniprotkb:A6NI71|uniprotkb:Q9UHY0|uniprotkb:Q5SSJ6 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:hp1b3_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short)|uniprotkb:Protein HP1-BP74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000127483(gene)|ensembl:ENST00000312239(transcript)|ensembl:ENST00000438032(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|mint:Q5SSJ5|rcsb pdb:2RQP|go:"GO:0005694"(chromosome)|refseq:XP_016856882.1|refseq:XP_016856883.1|refseq:XP_011539834.1|refseq:XP_011539835.1|refseq:XP_011539836.1|refseq:NP_057371.2|refseq:XP_005245932.1|refseq:XP_005245933.1|refseq:XP_005245934.1|refseq:XP_005245935.1|refseq:XP_005245936.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:kLFithZZv+Qn9YLElEnX81awKDw9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BZE4 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1056249|uniprotkb:O95446|uniprotkb:Q9NVJ8|uniprotkb:B3KMC5|uniprotkb:B4DY13|uniprotkb:B7Z7A3|uniprotkb:Q5T3R8|ensembl:ENSP00000354040 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:gtpb4_human(display_long)|uniprotkb:GTPBP4(gene name)|psi-mi:GTPBP4(display_short)|uniprotkb:CRFG(gene name synonym)|uniprotkb:NOG1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_036473.2|ensembl:ENSG00000107937(gene)|ensembl:ENST00000360803(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q9BZE4|rcsb pdb:6LSS|rcsb pdb:6LU8 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:wTcBrIj6c27um4RnJH81grRgutc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9Y2X3 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P33176 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_004512.1|ensembl:ENSG00000170759(gene)|ensembl:ENST00000302418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-29244N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P07339 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q15061 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2563523|uniprotkb:Q92577|uniprotkb:Q15395|ensembl:ENSP00000384302 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:wdr43_human(display_long)|uniprotkb:WDR43(gene name)|psi-mi:WDR43(display_short)|uniprotkb:KIAA0007(gene name synonym)|uniprotkb:UTP5(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 5 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_055946.1|ensembl:ENSG00000163811(gene)|ensembl:ENST00000407426(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003711"(transcription elongation regulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q15061|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:5YWzMczifqbhFvvX1HkF3XYW6xA9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P26640 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-355765|uniprotkb:Q5JQ90|uniprotkb:Q96E77|uniprotkb:Q9UQM2|uniprotkb:B4DZ61|uniprotkb:B0V1N1|ensembl:ENSP00000211402|ensembl:ENSP00000364815|ensembl:ENSP00000401121|ensembl:ENSP00000403359|ensembl:ENSP00000415316 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:syvc_human(display_long)|uniprotkb:VARS1(gene name)|psi-mi:VARS1(display_short)|uniprotkb:G7A(gene name synonym)|uniprotkb:Protein G7a(gene name synonym)|uniprotkb:VARS(gene name synonym)|uniprotkb:VARS2(gene name synonym)|uniprotkb:Valyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_006286.1|ensembl:ENSG00000096171(gene)|ensembl:ENSG00000204394(gene)|ensembl:ENSG00000224264(gene)|ensembl:ENSG00000226589(gene)|ensembl:ENSG00000231116(gene)|ensembl:ENST00000211402(transcript)|ensembl:ENST00000375663(transcript)|ensembl:ENST00000422694(transcript)|ensembl:ENST00000435657(transcript)|ensembl:ENST00000457796(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:P26640|reactome:R-HSA-379716 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:aPfpK0/C2KpCsMOI0sjCreufI509606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8WXX5 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P13489 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14839 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8NE71 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-720571|uniprotkb:A2BF75|uniprotkb:O14897|uniprotkb:Q69YP6|ensembl:ENSP00000313603|ensembl:ENSP00000373082|ensembl:ENSP00000389065|ensembl:ENSP00000411327|ensembl:ENSP00000412553|ensembl:ENSP00000413319|ensembl:ENSP00000414373 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:abcf1_human(display_long)|uniprotkb:ATP-binding cassette 50(gene name synonym)|uniprotkb:TNF-alpha-stimulated ABC protein(gene name synonym)|uniprotkb:ABCF1(gene name)|psi-mi:ABCF1(display_short)|uniprotkb:ABC50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001020262.1|refseq:NP_001081.1|dip:DIP-50666N|ensembl:ENSG00000204574(gene)|ensembl:ENSG00000206490(gene)|ensembl:ENSG00000225989(gene)|ensembl:ENSG00000231129(gene)|ensembl:ENSG00000232169(gene)|ensembl:ENSG00000236149(gene)|ensembl:ENSG00000236342(gene)|ensembl:ENST00000326195(transcript)|ensembl:ENST00000383588(transcript)|ensembl:ENST00000419893(transcript)|ensembl:ENST00000423247(transcript)|ensembl:ENST00000426219(transcript)|ensembl:ENST00000457078(transcript)|ensembl:ENST00000457111(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0016020"(membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|mint:Q8NE71|rcsb pdb:5ZXD|reactome:R-HSA-382556 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:DdEbnAZo4bv75DRSzSmcdNo6QsM9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O15355 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-725702|ensembl:ENSP00000342778 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O76021 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q5RKV6 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2841747|ensembl:ENSP00000398597 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9H8H0 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P46821 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O95478 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2852366|ensembl:ENSP00000483484 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nsa2_human(display_long)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:TINP1(gene name synonym)|uniprotkb:Hairy cell leukemia protein 1(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:HUSSY-29(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_055701.1|refseq:NP_001258594.1|ensembl:ENSG00000164346(gene)|ensembl:ENST00000610426(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:O95478 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:UHmCVn1q0LfipKMzSFQUzmVULD49606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NYH9 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-749211|uniprotkb:Q8IX96|uniprotkb:Q96BL2|uniprotkb:Q9NQ91|ensembl:ENSP00000261708 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:utp6_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated antigen 66(gene name synonym)|uniprotkb:Multiple hat domains protein(gene name synonym)|uniprotkb:UTP6(gene name)|psi-mi:UTP6(display_short)|uniprotkb:C17orf40(gene name synonym)|uniprotkb:HCA66(gene name synonym)|uniprotkb:MHAT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_060898.2|ensembl:ENSG00000108651(gene)|ensembl:ENST00000261708(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0030515"(snoRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013949(U3 small nucleolar RNA-associated protein 6)|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:hMKHMRXUFqGjWKsyi9MedHMilhc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q15424 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-348298|ensembl:ENSP00000292123|uniprotkb:O60406|uniprotkb:B7Z5B6|uniprotkb:F5H0H3|uniprotkb:Q59HH8|uniprotkb:A0AV56|uniprotkb:B7ZLP6 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:safb1_human(display_long)|uniprotkb:SAFB(gene name)|psi-mi:SAFB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HET(gene name synonym)|uniprotkb:SAFB1(gene name synonym)|uniprotkb:HSP27 estrogen response element-TATA box-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030496"(midbody)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000160633(gene)|interpro:IPR034781|interpro:IPR035979|ensembl:ENST00000292123(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|interpro:IPR036361|mint:Q15424|reactome:R-HSA-3899300|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|refseq:NP_002958.2|refseq:NP_001307500.1|refseq:NP_001307501.1|refseq:NP_001188269.1|refseq:NP_001188267.1|refseq:NP_001188268.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:Y31we6crSBL4G6uviNAfXyX0xfM9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O95757 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q99426 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-764356|uniprotkb:O00111|uniprotkb:O00674|uniprotkb:O14728|uniprotkb:Q6FGY5|ensembl:ENSP00000221855 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:tbcb_human(display_long)|uniprotkb:Tubulin-specific chaperone B(gene name synonym)|uniprotkb:Cytoskeleton-associated protein 1(gene name synonym)|uniprotkb:Cytoskeleton-associated protein CKAPI(gene name synonym)|uniprotkb:TBCB(gene name)|psi-mi:TBCB(display_short)|uniprotkb:CG22(gene name synonym)|uniprotkb:CKAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001272.2|refseq:NP_001287900.1|dip:DIP-34409N|ensembl:ENSG00000105254(gene)|ensembl:ENST00000221855(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000626(Ubiquitin)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR029071|interpro:IPR036859|reactome:R-HSA-389977|go:"GO:0030154"(cell differentiation) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:HHMamwtPQscu/rkhdarbQl6/hcw9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BQG0 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P13667 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9HCE1 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q07021 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14257 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q5JTH9 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-310743|uniprotkb:Q5JTH8|uniprotkb:Q69YK4|uniprotkb:Q96E87|uniprotkb:Q9BUH3|uniprotkb:Q9Y4C7|intact:EBI-2558452|uniprotkb:B4DK00|uniprotkb:E9PCK7|intact:EBI-28986119|ensembl:ENSP00000360031|ensembl:ENSP00000446184 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rrp12_human(display_long)|uniprotkb:RRP12(gene name)|psi-mi:RRP12(display_short)|uniprotkb:KIAA0690(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001138586.1|refseq:NP_055994.2|refseq:NP_001271266.1|ensembl:ENST00000315563|ensembl:ENSP00000324315|ensembl:ENSP00000360031|ensembl:ENST00000414986|ensembl:ENSP00000414863|ensembl:ENSP00000446184|ensembl:ENSG00000052749(gene)|ensembl:ENST00000370992(transcript)|ensembl:ENST00000536831(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012978(Region of unknown function, NUC173)|interpro:IPR016024(Armadillo-type fold)|mint:Q5JTH9 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:O2Ih3mwXBDMynmqc4UzvizKVnNg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q2NL82 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-358058|intact:EBI-1048757|intact:EBI-1210739|uniprotkb:Q8WUY5|uniprotkb:Q9NVT0|uniprotkb:Q9P2E6|intact:EBI-2558422|ensembl:ENSP00000301364 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:tsr1_human(display_long)|uniprotkb:TSR1(gene name)|psi-mi:TSR1(display_short)|uniprotkb:KIAA1401(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_060598.3|ensembl:ENSG00000167721(gene)|ensembl:ENST00000301364(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR030387|interpro:IPR039761|mint:Q2NL82|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6ZMT|rcsb pdb:6ZN5|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:+ZPt5nSRzZbW3tD1IAcdeo5kH309606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9H6R4 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2514288|ensembl:ENSP00000297990|uniprotkb:Q5T5M4|uniprotkb:Q8TEZ0|uniprotkb:Q8TEZ1|uniprotkb:Q8TEY9|uniprotkb:Q7L4G6|uniprotkb:Q5T5M3|uniprotkb:Q8N6I0|uniprotkb:Q9H675 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nol6_human(display_long)|uniprotkb:NOL6(gene name)|psi-mi:NOL6(display_short)|uniprotkb:Nucleolar RNA-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000165271(gene)|ensembl:ENST00000297990(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|interpro:IPR005554(Nrap protein)|interpro:IPR035082|interpro:IPR035367|interpro:IPR035368|interpro:IPR035369|interpro:IPR035370|interpro:IPR035371|mint:Q9H6R4|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_075068.2|refseq:NP_631981.2 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:e1Waxlhmq+KTKwHTV13aWEpVF4k9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q99613 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q02790 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1047444|uniprotkb:D3DUQ1|uniprotkb:Q9UCP1|uniprotkb:Q9UCV7|ensembl:ENSP00000001008 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:fkbp4_human(display_long)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:FKBP4(gene name)|psi-mi:FKBP4(display_short)|uniprotkb:FKBP52(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_002005.1|go:"GO:0070062"(extracellular exosome)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR031212|mint:Q02790|rcsb pdb:1N1A|rcsb pdb:1P5Q|rcsb pdb:1Q1C|rcsb pdb:1QZ2|rcsb pdb:4DRJ|rcsb pdb:4LAV|rcsb pdb:4LAW|rcsb pdb:4LAX|rcsb pdb:4LAY|rcsb pdb:4TW8|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6RCY|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|ensembl:ENST00000001008(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|ensembl:ENSG00000004478(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0006825"(copper ion transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0032767"(copper-dependent protein binding)|dip:DIP-50866N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:N0vDRDgcQ2x8xiWKdX9Zt+cHcsQ9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q5QJE6 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-5666736|ensembl:ENSP00000411010|uniprotkb:Q53H59|uniprotkb:Q86WX9|uniprotkb:Q76MJ8|uniprotkb:Q12987|uniprotkb:Q6TLI0|uniprotkb:Q5TFJ4 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:tdif2_human(display_long)|uniprotkb:ERBP(gene name synonym)|uniprotkb:Estrogen receptor-binding protein(gene name synonym)|uniprotkb:LPTS-interacting protein 2(gene name synonym)|uniprotkb:TDIF2(gene name synonym)|uniprotkb:Terminal deoxynucleotidyltransferase-interacting factor 2(gene name synonym)|uniprotkb:DNTTIP2(gene name)|psi-mi:DNTTIP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000067334(gene)|ensembl:ENST00000436063(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR014810(Fcf2 pre-rRNA processing)|interpro:IPR039883|refseq:NP_055412.2 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:GSN2/hZ+HZb29LuBvv2RVMawmNA9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q96GQ7 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-722051|uniprotkb:A0AVB6|uniprotkb:Q5VXM7|uniprotkb:Q8WYG4|uniprotkb:Q969N7|uniprotkb:Q96F57|uniprotkb:Q96L97|uniprotkb:Q9BWY9|uniprotkb:Q9BXF0|uniprotkb:Q9H990|uniprotkb:Q9NWU3|uniprotkb:Q9P0C2|uniprotkb:Q9UGD6|uniprotkb:B7ZLY1 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ddx27_human(display_long)|uniprotkb:DEAD box protein 27(gene name synonym)|uniprotkb:DDX27(gene name)|psi-mi:DDX27(display_short)|uniprotkb:RHLP(gene name synonym)|uniprotkb:cPERP-F(gene name synonym)|uniprotkb:HSPC259(orf name)|uniprotkb:PP3241(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) interpro:IPR027417|refseq:NP_060365.7|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|mint:Q96GQ7|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:Z4Dm6lxXyqB18+uPxROJszLWYdE9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P46087 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-356811|uniprotkb:A1A4Z3|uniprotkb:Q0P5S5|uniprotkb:Q58F30|uniprotkb:B3KPD6|uniprotkb:Q05BA7|uniprotkb:Q3KQS4|ensembl:ENSP00000313272|ensembl:ENSP00000444437 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nop2_human(display_long)|uniprotkb:NOP2(gene name)|psi-mi:NOP2(display_short)|uniprotkb:NSUN1(gene name synonym)|uniprotkb:Proliferating-cell nucleolar antigen p120(gene name synonym)|uniprotkb:Proliferation-associated nucleolar protein p120(gene name synonym)|uniprotkb:NOL1(gene name synonym)|uniprotkb:Nucleolar protein 2 homolog(gene name synonym)|uniprotkb:Nucleolar protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001028886.1|refseq:NP_006161.2|refseq:NP_001245237.1|refseq:NP_001245238.1|refseq:NP_001245239.1|refseq:XP_005253748.1|ensembl:ENSG00000111641(gene)|ensembl:ENST00000322166(transcript)|ensembl:ENST00000537442(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR012586(P120R)|interpro:IPR018314|interpro:IPR023267|interpro:IPR023273|interpro:IPR029063|interpro:IPR031341|mint:P46087|reactome:R-HSA-6790901|reactome:R-HSA-8869496 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:CvYaCDv8N8OvS0lPFy8jFEFaOTA9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O15381 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-721638|uniprotkb:Q96EM7|uniprotkb:B4DMC4|uniprotkb:B4DP98|ensembl:ENSP00000281701 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nvl_human(display_long)|uniprotkb:NVL(gene name)|psi-mi:NVL(display_short)|uniprotkb:NVL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_002524.2|refseq:NP_996671.1|refseq:NP_001230075.1|refseq:NP_001230076.1|ensembl:ENSG00000143748(gene)|ensembl:ENST00000281701(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1904749"(regulation of protein localization to nucleolus)|go:"GO:1990275"(preribosome binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR031996|interpro:IPR038100|interpro:IPR041569|mint:O15381|rcsb pdb:2X8A|rcsb pdb:6RO1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:3xAHor7LoQCGSzrRQWhKaEuqd9A9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P11940 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9H0A0 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9Y3T9 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9Y3C1 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P39748 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-707816|ensembl:ENSP00000305480 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:fen1_human(display_long)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:Maturation factor 1(gene name synonym)|uniprotkb:DNase IV(gene name synonym)|uniprotkb:FEN1(gene name)|psi-mi:FEN1(display_short)|uniprotkb:RAD2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000168496(gene)|ensembl:ENST00000305885(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|refseq:NP_004102.1|dip:DIP-24216N|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007613"(memory)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR023426|interpro:IPR029060|interpro:IPR036279|mint:P39748|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:3Q8K|rcsb pdb:3Q8L|rcsb pdb:3Q8M|rcsb pdb:3UVU|rcsb pdb:5E0V|rcsb pdb:5FV7|rcsb pdb:5K97|rcsb pdb:5KSE|rcsb pdb:5UM9|rcsb pdb:5ZOD|rcsb pdb:5ZOE|rcsb pdb:5ZOF|rcsb pdb:5ZOG|rcsb pdb:6TNZ|reactome:R-HSA-110362|reactome:R-HSA-162594|reactome:R-HSA-174437|reactome:R-HSA-5651801|reactome:R-HSA-5685939|reactome:R-HSA-69166 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:l9A+/Q39cGBPac0d8USNWE+17NM9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q99848 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P31153 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P06702 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q01780 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9GZL7 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2490660|uniprotkb:B3KPA9|uniprotkb:Q96HU0|uniprotkb:Q9NV80|uniprotkb:Q9NYI8|ensembl:ENSP00000261015 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:wdr12_human(display_long)|uniprotkb:WDR12(gene name)|psi-mi:WDR12(display_short)|uniprotkb:WD repeat-containing protein 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:0007219"(Notch signaling pathway)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR012972(NLE)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR028599|interpro:IPR036322|mint:Q9GZL7|rcsb pdb:6N31|rcsb pdb:6P0Q|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000138442(gene)|ensembl:ENST00000261015(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|refseq:NP_060726.3 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:7qCdIJOJA36eRlrwJA6x0XC/Tqc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P12956 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q15269 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-722224|uniprotkb:Q96A77|uniprotkb:B2RAG8|ensembl:ENSP00000291576 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pwp2_human(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:PWP2H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005040.2|refseq:XP_006723973.1|refseq:XP_011507205.1|ensembl:ENSG00000241945(gene)|ensembl:ENST00000291576(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:PYs2LKd3EMjAnp0engZvZn0CeBo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9Y262 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-373519|uniprotkb:Q53HQ1|uniprotkb:Q53HT4|uniprotkb:Q5QTR1|uniprotkb:Q5TI15|uniprotkb:Q6ICD2|uniprotkb:B2RDG6|uniprotkb:B4DYB2|uniprotkb:G8JLH4|intact:EBI-10970119|ensembl:ENSP00000485663|ensembl:ENSP00000499067 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:eif3l_human(display_long)|uniprotkb:EIF3L(gene name)|psi-mi:EIF3L(display_short)|uniprotkb:HSPC021(orf name)|uniprotkb:HSPC025(orf name)|uniprotkb:EIF3S6IP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6-interacting protein(gene name synonym)|uniprotkb:MSTP005(orf name)|uniprotkb:EIF3EIP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit E-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_057175.1|refseq:NP_001229852.1|dip:DIP-31172N|ensembl:ENSG00000100129(gene)|ensembl:ENST00000624234(transcript)|ensembl:ENST00000652021(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|mint:Q9Y262|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:C9ES0WpTdEHUkjWeZK/SoDP/dAo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P31939 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1048599|uniprotkb:Q13856|uniprotkb:Q53S28|uniprotkb:A8K202|uniprotkb:E9PBU3|ensembl:ENSP00000236959 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pur9_human(display_long)|uniprotkb:ATIC(gene name)|psi-mi:ATIC(display_short)|uniprotkb:PURH(gene name synonym)|uniprotkb:OK/SW-cl.86(orf name)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_004035.2|ensembl:ENSG00000138363(gene)|ensembl:ENST00000236959(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|rcsb pdb:1P4R|rcsb pdb:1PKX|rcsb pdb:1PL0|rcsb pdb:5UY8|rcsb pdb:5UZ0|reactome:R-HSA-73817 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:Xe3388w/LOBYgag9P8Gp3IGo9wU9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8N9T8 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-724923|uniprotkb:Q2M1R5|uniprotkb:Q2M1R7|uniprotkb:Q7L5J7|uniprotkb:Q96G92|uniprotkb:Q9BU50|uniprotkb:Q9H6I1|uniprotkb:Q9H978|ensembl:ENSP00000320917 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:kri1_human(display_long)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_075384.3|ensembl:ENSG00000129347(gene)|ensembl:ENST00000312962(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|mint:Q8N9T8 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:sIRmrP/c3tSmEAj1usRGN3R3Bh09606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q13310 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q92979 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-718638|uniprotkb:O00675|uniprotkb:O00726|ensembl:ENSP00000470560 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nep1_human(display_long)|uniprotkb:Nucleolar protein EMG1 homolog(gene name synonym)|uniprotkb:Protein C2f(gene name synonym)|uniprotkb:EMG1(gene name)|psi-mi:EMG1(display_short)|uniprotkb:C2F(gene name synonym)|uniprotkb:18S rRNA Psi1248 methyltransferase(gene name synonym)|uniprotkb:Ribosome biogenesis protein NEP1(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1248)-N1)-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_006322.4|refseq:NP_001306978.1|ensembl:ENSG00000126749(gene)|ensembl:ENST00000599672(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0017126"(nucleologenesis)|go:"GO:0019843"(rRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|interpro:IPR029026|interpro:IPR029028|mint:Q92979|rcsb pdb:5FAI|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:zIhyWwzd8MtIUn9JyWbXPHeGpF49606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q92900 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NXF1 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2371062|uniprotkb:Q5T722|uniprotkb:Q5T723|uniprotkb:Q8NCN8|uniprotkb:Q8TDY0|uniprotkb:B4DYV2|ensembl:ENSP00000364037 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:tex10_human(display_long)|uniprotkb:TEX10(gene name)|psi-mi:TEX10(display_short)|uniprotkb:L18(orf name)|uniprotkb:Nbla10363(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_060216.2|refseq:NP_001155056.1|ensembl:ENSG00000136891(gene)|ensembl:ENST00000374902(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0071339"(MLL1 complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024679|interpro:IPR037947|mint:Q9NXF1|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:cQcRo1eExRkr/an7wvBN8Ttyatc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P55265 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O14929 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P26358 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-719459|uniprotkb:Q9UHG5|uniprotkb:Q9ULA2|uniprotkb:Q9UMZ6|uniprotkb:A0AV63|intact:EBI-28971395|ensembl:ENSP00000345739|uniprotkb:B7ZLW6 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:dnmt1_human(display_long)|uniprotkb:CXXC9(gene name synonym)|uniprotkb:MCMT(gene name synonym)|uniprotkb:DNA methyltransferase HsaI(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 9(gene name synonym)|uniprotkb:DNMT1(gene name)|psi-mi:DNMT1(display_short)|uniprotkb:AIM(gene name synonym)|uniprotkb:DNMT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSP00000345739|ensembl:ENST00000359526|ensembl:ENSP00000352516|refseq:NP_001124295.1|refseq:NP_001370.1|ensembl:ENSG00000130816(gene)|ensembl:ENST00000340748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|refseq:NP_001305659.1|refseq:NP_001305660.1|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905931"(negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR010506(DMAP1-binding)|interpro:IPR017198("DNA (cytosine-5)-methyltransferase 1")|interpro:IPR018117|interpro:IPR022702|interpro:IPR029063|interpro:IPR031303|interpro:IPR043151|mint:P26358|rcsb pdb:3EPZ|rcsb pdb:3PTA|rcsb pdb:3SWR|rcsb pdb:4WXX|rcsb pdb:4YOC|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5WVO|rcsb pdb:5YDR|rcsb pdb:6K3A|reactome:R-HSA-212300|dip:DIP-39693N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:qae3zQwGP5R/+WCWoeahDKZ/9Jg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P05109 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q13601 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O60832 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-713091|ensembl:ENSP00000358563|uniprotkb:O43845|uniprotkb:Q96G67|uniprotkb:Q9Y505|uniprotkb:F5BSB3 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:dkc1_human(display_long)|uniprotkb:Dyskerin(gene name synonym)|uniprotkb:Nucleolar protein family A member 4(gene name synonym)|uniprotkb:snoRNP protein DKC1(gene name synonym)|uniprotkb:Nopp140-associated protein of 57 kDa(gene name synonym)|uniprotkb:Nucleolar protein NAP57(gene name synonym)|uniprotkb:CBF5 homolog(gene name synonym)|uniprotkb:DKC1(gene name)|psi-mi:DKC1(display_short)|uniprotkb:NOLA4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|mint:O60832|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901|interpro:IPR002478(PUA)|ensembl:ENSG00000130826(gene)|ensembl:ENST00000369550(transcript)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003720"(telomerase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990481"(mRNA pseudouridine synthesis)|go:"GO:0006396"(RNA processing)|refseq:NP_001354.1|refseq:NP_001135935.1|refseq:NP_001275676.1|dip:DIP-40645N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:njIdhtX9m37BslwxyAAV/JoRrHo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P78316 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-5454840|uniprotkb:D3DVR6|uniprotkb:Q7LGI5|uniprotkb:Q7Z6K0|uniprotkb:Q8TBR6|ensembl:ENSP00000315674|ensembl:ENSP00000405068 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nop14_human(display_long)|uniprotkb:NOP14(gene name)|psi-mi:NOP14(display_short)|uniprotkb:C4orf9(gene name synonym)|uniprotkb:NOL14(gene name synonym)|uniprotkb:Nucleolar complex protein 14(gene name synonym)|uniprotkb:RES4-25(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001278907.1|refseq:NP_001278908.1|refseq:NP_003694.1|ensembl:ENSG00000087269(gene)|ensembl:ENST00000314262(transcript)|ensembl:ENST00000416614(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0030692"(Noc4p-Nop14p complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007276(Nop14-like protein)|mint:P78316|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:UFAZjZG2vkmiElijCj5ZXZNc35Y9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P16403 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NZM5 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_056525.2|ensembl:ENSG00000105373(gene)|ensembl:ENST00000246802(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0003723"(RNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990173"(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|go:"GO:0050821"(protein stabilization) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P46013 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-876367|uniprotkb:Q5VWH2|ensembl:ENSP00000357643 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ki67_human(display_long)|uniprotkb:MKI67(gene name)|psi-mi:MKI67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001139438.1|refseq:NP_002408.3|dip:DIP-28132N|ensembl:ENSG00000148773(gene)|ensembl:ENST00000368654(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012568(K167R)|interpro:IPR029334|mint:P46013|rcsb pdb:1R21|rcsb pdb:2AFF|rcsb pdb:5J28 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:kyrLLOv4HSqah1Y6HtzebG978Kw9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14669 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N - isoform-comment:Major isoform. caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NP81 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1049768|uniprotkb:A6NHW7|uniprotkb:Q9BVP3|uniprotkb:B4DE10|ensembl:ENSP00000221431|ensembl:ENSP00000489539 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:sysm_human(display_long)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)|uniprotkb:SerRSmt(gene name synonym)|uniprotkb:SARS2(gene name)|psi-mi:SARS2(display_short)|uniprotkb:SARSM(gene name synonym)|uniprotkb:Seryl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001139373.1|refseq:NP_060297.1|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR033729|interpro:IPR042103|mint:Q9NP81|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|reactome:R-HSA-379726|ensembl:ENSG00000104835(gene)|ensembl:ENSG00000283104(gene)|ensembl:ENST00000221431(transcript)|ensembl:ENST00000634687(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0070158"(mitochondrial seryl-tRNA aminoacylation)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process") - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:xYa2ZQIifKicNHV/6vlcUGaN9q49606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O00566 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-5235884|uniprotkb:A0AVJ8|ensembl:ENSP00000244230 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:mpp10_human(display_long)|uniprotkb:MPHOSPH10(gene name)|psi-mi:MPHOSPH10(display_short)|uniprotkb:MPP10(gene name synonym)|uniprotkb:M phase phosphoprotein 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005782.1|ensembl:ENSG00000124383(gene)|ensembl:ENST00000244230(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR012173(U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p)|mint:O00566|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:xkz11U1x5r2joVtVq6JG4asO1Qw9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8NEJ9 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-9995414|uniprotkb:A8K760|uniprotkb:Q9Y400|ensembl:ENSP00000386134 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ngdn_human(display_long)|uniprotkb:NGDN(gene name)|psi-mi:NGDN(display_short)|uniprotkb:C14orf120(gene name synonym)|uniprotkb:Centromere accumulated nuclear protein 1(gene name synonym)|uniprotkb:EIF4E-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001036100.1|refseq:NP_056329.1|ensembl:ENSG00000129460(gene)|ensembl:ENST00000408901(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006417"(regulation of translation)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032040"(small-subunit processome)|interpro:IPR007146(Small-subunit processome, Utp3)|mint:Q8NEJ9 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:dzn7QntKCrb97VLlmUMizp+0CV49606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q92522 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O15213 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-9995439|uniprotkb:A6NDP5|uniprotkb:Q5HYZ0|uniprotkb:Q5STK5|uniprotkb:Q5STR3|ensembl:ENSP00000363746|ensembl:ENSP00000372695|ensembl:ENSP00000399454|ensembl:ENSP00000402869|ensembl:ENSP00000405614 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:wdr46_human(display_long)|uniprotkb:WDR46(gene name)|psi-mi:WDR46(display_short)|uniprotkb:BING4(gene name synonym)|uniprotkb:C6orf11(gene name synonym)|uniprotkb:WD repeat-containing protein BING4(gene name synonym)|uniprotkb:FP221(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001157739.1|refseq:NP_005443.3|ensembl:ENSG00000204221(gene)|ensembl:ENSG00000206284(gene)|ensembl:ENSG00000226916(gene)|ensembl:ENSG00000227057(gene)|ensembl:ENSG00000236222(gene)|ensembl:ENST00000374617(transcript)|ensembl:ENST00000383208(transcript)|ensembl:ENST00000432609(transcript)|ensembl:ENST00000432933(transcript)|ensembl:ENST00000457382(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR040315|mint:O15213|reactome:R-HSA-6790901|reactome:R-HSA-6791226|interpro:IPR012952(BING4, C-terminal) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:BYhBAazSJnKN4c7RgWU2WygOk4o9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O43776 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-373505|uniprotkb:Q53GU6|uniprotkb:B4DG16|ensembl:ENSP00000256854 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:sync_human(display_long)|uniprotkb:NARS1(gene name)|psi-mi:NARS1(display_short)|uniprotkb:Asparaginyl-tRNA synthetase(gene name synonym)|uniprotkb:Asparaginyl-tRNA synthetase 1(gene name synonym)|uniprotkb:NARS(gene name synonym)|uniprotkb:NRS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_004530.1|ensembl:ENSG00000134440(gene)|ensembl:ENST00000256854(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004816"(asparagine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006421"(asparaginyl-tRNA aminoacylation)|go:"GO:0016477"(cell migration)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031728"(CCR3 chemokine receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004522(Asparaginyl-tRNA synthetase, class IIb)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:4ZYA|rcsb pdb:5XIX|reactome:R-HSA-379716 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:yCKLNQEoXyLaJC0PpYOoefQawss9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q12788 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-715766|uniprotkb:Q59GD6|uniprotkb:Q8IVB7|intact:EBI-749106|uniprotkb:Q96A78|ensembl:ENSP00000454836 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:tbl3_human(display_long)|uniprotkb:WD repeat-containing protein SAZD(gene name synonym)|uniprotkb:TBL3(gene name)|psi-mi:TBL3(display_short)|uniprotkb:SAZD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_006444.2|ensembl:ENSG00000183751(gene)|ensembl:ENST00000568546(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013934(Small-subunit processome, Utp13)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q12788|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:XFWYZxef3kNBYeTaoSBWEXQoF/M9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8NC51 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q13823 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1043365|uniprotkb:Q9BWN7|ensembl:ENSP00000362153 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nog2_human(display_long)|uniprotkb:Autoantigen NGP-1(gene name synonym)|uniprotkb:GNL2(gene name)|psi-mi:GNL2(display_short)|uniprotkb:NGP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000134697(gene)|ensembl:ENST00000373062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q13823|rcsb pdb:6LSS|rcsb pdb:6LU8|refseq:NP_037417.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:CgIg/QNhk71SHIhV4iLvIuC/HUo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q969X6 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O15226 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-766011|uniprotkb:Q4VC41|uniprotkb:Q9UJ91|uniprotkb:G3V1N1|ensembl:ENSP00000304803 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:nkrf_human(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Protein ITBA4(gene name synonym)|uniprotkb:NKRF(gene name)|psi-mi:NKRF(display_short)|uniprotkb:ITBA4(gene name synonym)|uniprotkb:NRF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001166958.1|refseq:NP_001166959.1|refseq:NP_060014.2|refseq:XP_011529667.1|dip:DIP-34570N|ensembl:ENSG00000186416(gene)|ensembl:ENST00000304449(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036867|mint:O15226|rcsb pdb:6SH6|rcsb pdb:6SH7|interpro:IPR034071 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:jH7qlOvuAHKsjuOyzDpBonpgtF09606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9Y3B9 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1055610|intact:EBI-28979625|ensembl:ENSP00000355899 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rrp15_human(display_long)|uniprotkb:Ribosomal RNA-processing protein 15(gene name synonym)|uniprotkb:RRP15(gene name)|psi-mi:RRP15(display_short)|uniprotkb:KIAA0507(gene name synonym)|uniprotkb:CGI-115(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSP00000355899|refseq:NP_057136.2|ensembl:ENSG00000067533(gene)|ensembl:ENST00000366932(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR012459(Protein of unknown function DUF1665) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:EJQFG76HKEYeJ6LwFd5zaUmoScw9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P43487 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1032909|uniprotkb:Q53EY3|ensembl:ENSP00000327583 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rang_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_002873.1|ensembl:ENSG00000099901(gene)|ensembl:ENST00000331821(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1K5D|rcsb pdb:1K5G|reactome:R-HSA-165054|refseq:NP_001265568.1|refseq:NP_001265569.1|dip:DIP-35058N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:OWndphaUCDSO3+MGhJqcuQo2Lk09606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q03701 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P52701 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:O75691 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-356062|uniprotkb:Q9H3H4|ensembl:ENSP00000261637 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:utp20_human(display_long)|uniprotkb:UTP20(gene name)|psi-mi:UTP20(display_short)|uniprotkb:DRIM(gene name synonym)|uniprotkb:Down-regulated in metastasis protein(gene name synonym)|uniprotkb:Protein Key-1A6(gene name synonym)|uniprotkb:Novel nucleolar protein 73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_055318.2|ensembl:ENSG00000120800(gene)|ensembl:ENST00000261637(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|interpro:IPR011430(Down-regulated in metastasis)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:OxTEfw2MtOijthWHjRtqIqUUjjg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BVJ6 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-473284|uniprotkb:B4DQ08|uniprotkb:E9PEL7|uniprotkb:Q5JYF1|uniprotkb:A8MVQ1|uniprotkb:A8K7A3|ensembl:ENSP00000377944 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ut14a_human(display_long)|uniprotkb:Serologically defined colon cancer antigen 16(gene name synonym)|uniprotkb:Antigen NY-CO-16(gene name synonym)|uniprotkb:UTP14A(gene name)|psi-mi:UTP14A(display_short)|uniprotkb:SDCCAG16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000156697(gene)|ensembl:ENST00000394422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0032040"(small-subunit processome)|interpro:IPR006709(Small-subunit processome, Utp14)|mint:Q9BVJ6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001159693.1|refseq:NP_006640.2|dip:DIP-32505N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:vBBHvYYgh4LYP335ktHlQ77Dkfc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BYG3 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2561019|ensembl:ENSP00000285814|uniprotkb:Q8TB66|uniprotkb:A8K788|uniprotkb:Q96ED4 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:mk67i_human(display_long)|uniprotkb:NIFK(gene name)|psi-mi:NIFK(display_short)|uniprotkb:MKI67IP(gene name synonym)|uniprotkb:NOPP34(gene name synonym)|uniprotkb:Nucleolar phosphoprotein Nopp34(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q9BYG3|rcsb pdb:2AFF|ensembl:ENSG00000155438(gene)|ensembl:ENST00000285814(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_115766.3|dip:DIP-28134N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:DUc8AnzFxJjbK+cTW5H83GQcf6o9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BRX2 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1043580|uniprotkb:Q9GZS6|uniprotkb:Q9Y306|ensembl:ENSP00000274311 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pelo_human(display_long)|uniprotkb:PELO(gene name)|psi-mi:PELO(display_short)|uniprotkb:CGI-17(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000152684(gene)|ensembl:ENST00000274311(transcript)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007049"(cell cycle)|go:"GO:0007492"(endoderm development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|mint:Q9BRX2|rcsb pdb:1X52|rcsb pdb:5EO3|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|refseq:NP_057030.3 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:EZIi8JN2tu0u4oH06fOus3LKjoo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P42696 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2954772|ensembl:ENSP00000386226|uniprotkb:Q8N2Z8|uniprotkb:Q9H5A1|uniprotkb:A8K8J7 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:rbm34_human(display_long)|uniprotkb:RBM34(gene name)|psi-mi:RBM34(display_short)|uniprotkb:KIAA0117(gene name synonym)|uniprotkb:RNA-binding motif protein 34(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000188739(gene)|ensembl:ENST00000408888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR034220|interpro:IPR034221|interpro:IPR035979|mint:P42696|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_055829.2|refseq:NP_001333667.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:YrlnOTpyzg9F+4ZaZpLMfq4T4ts9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8TDD1 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:VzxEkRaOIND08jGJk3yyoztesjo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q7Z7K6 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1210604|uniprotkb:Q3L8N5|uniprotkb:Q8NFH6|uniprotkb:B2RPK2 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:cenpv_human(display_long)|uniprotkb:CENPV(gene name)|psi-mi:CENPV(display_short)|uniprotkb:Nuclear protein p30(gene name synonym)|uniprotkb:PRR6(gene name synonym)|uniprotkb:Proline-rich protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_859067.2|interpro:IPR006913(Glutathione-dependent formaldehyde-activating, GFA)|interpro:IPR011057(Mss4-like)|mint:Q7Z7K6|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0030496"(midbody)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0005829"(cytosol) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:q2Dt9PEcUigyqjqFMVm3dxk54B09606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P61158 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NRX1 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-712787|ensembl:ENSP00000263657|uniprotkb:Q53G13|uniprotkb:Q8WVB8|uniprotkb:A8K6Q0 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pno1_human(display_long)|uniprotkb:Partner of NOB1(gene name synonym)|uniprotkb:PNO1(gene name)|psi-mi:PNO1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000115946(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR004087(K Homology)|interpro:IPR036612|interpro:IPR039912|mint:Q9NRX1|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZXD|rcsb pdb:6ZXE|reactome:R-HSA-6790901|reactome:R-HSA-6791226|ensembl:ENST00000263657(transcript)|refseq:NP_064528.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:zxUnBMJ/10/uydzhq1t1UaNAwmo9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NUD5 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-2954851|uniprotkb:Q3B7J3|ensembl:ENSP00000484056|uniprotkb:Q6NT79 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:zchc3_human(display_long)|uniprotkb:ZCCHC3(gene name)|psi-mi:ZCCHC3(display_short)|uniprotkb:C20orf99(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000247315(gene)|ensembl:ENST00000500893(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR042509|refseq:NP_149080.2 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:7OjndwgSqExNYquAbdZ2zX2Ploc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P08621 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1049228|uniprotkb:P78493|uniprotkb:P78494|uniprotkb:Q15364|uniprotkb:Q15686|uniprotkb:Q15687|uniprotkb:Q15689|uniprotkb:Q99377|uniprotkb:Q9UE45|uniprotkb:Q9UE46|uniprotkb:Q9UE47|uniprotkb:Q9UE48|uniprotkb:Q9UFQ6|intact:EBI-3190943|uniprotkb:B3KUA3|ensembl:ENSP00000472998 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ru17_human(display_long)|uniprotkb:SNRNP70(gene name)|psi-mi:SNRNP70(display_short)|uniprotkb:RPU1(gene name synonym)|uniprotkb:U1AP1(gene name synonym)|uniprotkb:RNPU1Z(gene name synonym)|uniprotkb:SNRP70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_003080.2|refseq:NP_001287998.1|ensembl:ENSG00000104852(gene)|ensembl:ENST00000598441(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1904715"(negative regulation of chaperone-mediated autophagy)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR022023|interpro:IPR034143|interpro:IPR035979|mint:P08621|rcsb pdb:2L5I|rcsb pdb:2L5J|rcsb pdb:3CW1|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4PKD|rcsb pdb:6QX9|rcsb pdb:7B0Y|reactome:R-HSA-72163|dip:DIP-29406N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:/P72B69q5f0TX4vTr4GuRrtgiRM9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P00491 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-712238|ensembl:ENSP00000354532|uniprotkb:Q15160|uniprotkb:Q5PZ03|uniprotkb:B2R8S5|uniprotkb:D3DS00 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:pnph_human(display_long)|uniprotkb:Inosine phosphorylase(gene name synonym)|uniprotkb:PNP(gene name)|psi-mi:PNP(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Inosine-guanosine phosphorylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:0001882"(nucleoside binding)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006148"(inosine catabolic process)|go:"GO:0006149"(deoxyinosine catabolic process)|go:"GO:0006157"(deoxyadenosine catabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0006738"(nicotinamide riboside catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043101"(purine-containing compound salvage)|go:"GO:0046059"(dAMP catabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR011268(Inosine guanosine and xanthosine phosphorylase)|interpro:IPR011270(Purine nucleoside phosphorylase I, inosine and guanosine-specific)|interpro:IPR018099|interpro:IPR035994|mint:P00491|rcsb pdb:1M73|rcsb pdb:1PF7|rcsb pdb:1PWY|rcsb pdb:1RCT|rcsb pdb:1RFG|rcsb pdb:1RR6|rcsb pdb:1RSZ|rcsb pdb:1RT9|rcsb pdb:1ULA|rcsb pdb:1ULB|rcsb pdb:1V2H|rcsb pdb:1V3Q|rcsb pdb:1V41|rcsb pdb:1V45|rcsb pdb:1YRY|rcsb pdb:2A0W|rcsb pdb:2A0X|rcsb pdb:2A0Y|rcsb pdb:2OC4|rcsb pdb:2OC9|rcsb pdb:2ON6|rcsb pdb:2Q7O|rcsb pdb:3BGS|rcsb pdb:3D1V|rcsb pdb:3GB9|rcsb pdb:3GGS|ensembl:ENSG00000198805(gene)|ensembl:ENST00000361505(transcript)|go:"GO:0000255"(allantoin metabolic process)|rcsb pdb:3K8O|rcsb pdb:3K8Q|rcsb pdb:3PHB|rcsb pdb:4EAR|rcsb pdb:3INY|rcsb pdb:4EB8|rcsb pdb:4ECE|rcsb pdb:4GKA|rcsb pdb:5ETJ|rcsb pdb:5UGF|reactome:R-HSA-6798695|reactome:R-HSA-74217|reactome:R-HSA-74259|refseq:NP_000261.2|dip:DIP-50406N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:FOpaxV/M6HIA+THugPZDfN1ej1o9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14152 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NVP1 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-724378|ensembl:ENSP00000263239|uniprotkb:Q6GTZ9|uniprotkb:Q6IAU4|uniprotkb:Q92732|uniprotkb:Q9BQB7 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ddx18_human(display_long)|uniprotkb:DEAD box protein 18(gene name synonym)|uniprotkb:Myc-regulated DEAD box protein(gene name synonym)|uniprotkb:DDX18(gene name)|psi-mi:DDX18(display_short)|uniprotkb:cPERP-D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_006764.3|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025313|interpro:IPR027417|interpro:IPR044773|mint:Q9NVP1|rcsb pdb:3LY5|ensembl:ENSG00000088205(gene)|ensembl:ENST00000263239(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0071392"(cellular response to estradiol stimulus) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:RmupZbt33/w1V7Uq5vnRO36j2Tc9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9NR30 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P42285 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9UKD2 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1046493|ensembl:ENSP00000364320|uniprotkb:Q9BPV9|uniprotkb:Q5TG55|uniprotkb:Q96SS6|uniprotkb:B3KNB3 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:mrt4_human(display_long)|uniprotkb:MRTO4(gene name)|psi-mi:MRTO4(display_short)|uniprotkb:C1orf33(gene name synonym)|uniprotkb:MRT4(gene name synonym)|uniprotkb:Ribosome assembly factor MRTO4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000053372(gene)|ensembl:ENST00000330263(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:Q9UKD2|interpro:IPR033867|refseq:NP_057267.2 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:LpvX3By1Cp6MxlAx3d5qoDM3FNY9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9BRJ6 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-751612|ensembl:ENSP00000350011|ensembl:ENSP00000380286|ensembl:ENSP00000380288 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:cg050_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_115726.1|refseq:NP_001305181.1|ensembl:ENSG00000146540(gene)|ensembl:ENST00000357429(transcript)|ensembl:ENST00000397098(transcript)|ensembl:ENST00000397100(transcript)|interpro:IPR019327|mint:Q9BRJ6|go:"GO:0003723"(RNA binding) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q14151 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-352869|ensembl:ENSP00000252542|uniprotkb:Q8TB13|uniprotkb:B4DKG3|intact:EBI-2948582 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:safb2_human(display_long)|uniprotkb:SAFB2(gene name)|psi-mi:SAFB2(display_short)|uniprotkb:KIAA0138(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) ensembl:ENSG00000130254(gene)|ensembl:ENST00000252542(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|interpro:IPR035979|go:"GO:0042802"(identical protein binding)|interpro:IPR036361|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|mint:Q14151|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034782|refseq:NP_055464.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:4/eQxEPzUXIuUuqP2ogEL+zY31g9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P33991 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-374938|uniprotkb:Q8NEH1|uniprotkb:Q99658|ensembl:ENSP00000262105|ensembl:ENSP00000496964 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:mcm4_human(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:CDC21(gene name synonym)|uniprotkb:CDC21 homolog(gene name synonym)|uniprotkb:P1-CDC21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_005905.2|refseq:NP_877423.1|ensembl:ENSG00000104738(gene)|ensembl:ENST00000262105(transcript)|ensembl:ENST00000649973(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33991|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31729N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:emFkamsHmwBPzoJnPcaL4SaqAlU9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q9HB71 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-1047302|uniprotkb:O60666|ensembl:ENSP00000356652|uniprotkb:B2ZWH2|uniprotkb:Q5R371|uniprotkb:B3KSF1|uniprotkb:Q5R370 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:cybp_human(display_long)|uniprotkb:Siah-interacting protein(gene name synonym)|uniprotkb:S100A6-binding protein(gene name synonym)|uniprotkb:CACYBP(gene name)|psi-mi:CACYBP(display_short)|uniprotkb:S100A6BP(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:PNAS-107(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR015120(Siah interacting protein, N terminal)|interpro:IPR037201|interpro:IPR037893|mint:Q9HB71|rcsb pdb:1X5M|rcsb pdb:2A25|rcsb pdb:2A26|go:"GO:0071277"(cellular response to calcium ion)|refseq:NP_001007215.1|refseq:NP_055227.1|ensembl:ENSG00000116161(gene)|ensembl:ENST00000367679(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0015631"(tubulin binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|refseq:XP_016856535.1 - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:mvv1o19mLHBS3FDnATyOFsDoZvk9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:Q8IY81 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-744088|uniprotkb:Q8N3A3|uniprotkb:Q8WXX1|uniprotkb:Q9BWM4|uniprotkb:Q9NXT6|uniprotkb:D3DU22|uniprotkb:B2RCA5|ensembl:ENSP00000396673 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:spb1_human(display_long)|uniprotkb:FTSJ3(gene name)|psi-mi:FTSJ3(display_short)|uniprotkb:SB92(orf name)|uniprotkb:Protein ftsJ homolog 3(gene name synonym)|uniprotkb:Putative rRNA methyltransferase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_060117.3|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR024576|interpro:IPR028589|interpro:IPR029063|mint:Q8IY81|reactome:R-HSA-6791226|ensembl:ENSG00000108592(gene)|ensembl:ENST00000427159(transcript)|go:"GO:0000453"(enzyme-directed rRNA 2'-O-methylation)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008650"("rRNA (uridine-2'-O-)-methyltransferase activity")|go:"GO:0016435"("rRNA (guanine) methyltransferase activity")|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0031167"(rRNA methylation)|go:"GO:0062105"(RNA 2'-O-methyltransferase activity)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR012920(Spb1, C-terminal) - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:KIeyMWn9Zktm5lV7XI7v2bRA8og9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16666-2 uniprotkb:P09936 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542 psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995438|imex:IM-23523-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N - isoform-comment:Major isoform. - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606 intact-crc:2A2D7F5E14D49BF7|rigid:tbppQ3u211s02fD2PccMIvTd1mM false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q92878 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O60934 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q14676 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P56270 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1809742|uniprotkb:A8QJL9|uniprotkb:Q15703|uniprotkb:Q99443|uniprotkb:H3BQD6|uniprotkb:G5E927|uniprotkb:Q8NFN7|uniprotkb:C6G496|ensembl:ENSP00000313362 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:maz_human(display_long)|uniprotkb:Transcription factor Zif87(gene name synonym)|uniprotkb:Zinc finger protein 801(gene name synonym)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)|uniprotkb:Purine-binding transcription factor(gene name synonym)|uniprotkb:Pur-1(gene name synonym)|uniprotkb:ZF87(gene name synonym)|uniprotkb:ZNF801(gene name synonym)|uniprotkb:Serum amyloid A-activating factor-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002374.2|refseq:NP_001036004.1|refseq:NP_001263205.1|refseq:NP_001263204.1|ensembl:ENSG00000103495(gene)|ensembl:ENST00000322945(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P56270 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:zuCDXhF2wr8gmTyjBNse9kVUqSw9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9UPW6 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N - - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9Y462 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2849152|uniprotkb:Q9Y4J6|uniprotkb:Q6NX42|uniprotkb:B4DSV4|ensembl:ENSP00000276123|ensembl:ENSP00000362260 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zn711_human(display_long)|uniprotkb:ZNF711(gene name)|psi-mi:ZNF711(display_short)|uniprotkb:CMPX1(gene name synonym)|uniprotkb:ZNF6(gene name synonym)|uniprotkb:Zinc finger protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:XP_011529326.1|refseq:XP_011529328.1|refseq:NP_068838.3|refseq:XP_005262243.1|refseq:XP_005262244.1|refseq:XP_005262245.1|refseq:XP_005262246.1|refseq:NP_001317503.1|refseq:XP_016885294.1|refseq:XP_016885295.1|refseq:XP_016885296.1|refseq:XP_016885297.1|refseq:XP_016885298.1|ensembl:ENSG00000147180(gene)|ensembl:ENST00000276123(transcript)|ensembl:ENST00000373165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR006794(Zfx / Zfy transcription activation region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:+D8I1UK1AkHcgA4oKgk04+/Spvg9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O75531 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1055977|uniprotkb:O60558|uniprotkb:Q6FGG7|ensembl:ENSP00000310275|ensembl:ENSP00000416128|ensembl:ENSP00000432867|ensembl:ENSP00000433760 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:baf_human(display_long)|uniprotkb:BANF1(gene name)|psi-mi:BANF1(display_short)|uniprotkb:BAF(gene name synonym)|uniprotkb:BCRG1(gene name synonym)|uniprotkb:Breakpoint cluster region protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001137457.1|refseq:NP_003851.1|ensembl:ENST00000445560(transcript)|ensembl:ENST00000527348(transcript)|ensembl:ENST00000533166(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0097726"(LEM domain binding)|interpro:IPR004122(Barrier to autointegration factor, BAF)|interpro:IPR036617|mint:O75531|rcsb pdb:1CI4|rcsb pdb:1QCK|rcsb pdb:2BZF|rcsb pdb:2EZX|rcsb pdb:2EZY|rcsb pdb:2EZZ|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:6UNT|rcsb pdb:6URE|rcsb pdb:6URJ|rcsb pdb:6URK|rcsb pdb:6URL|rcsb pdb:6URN|rcsb pdb:6URR|rcsb pdb:6URZ|rcsb pdb:6US0|rcsb pdb:6US1|rcsb pdb:6US7|rcsb pdb:6USB|rcsb pdb:6USD|rcsb pdb:6USI|rcsb pdb:7NDY|ensembl:ENSG00000175334(gene)|ensembl:ENST00000312175(transcript)|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|reactome:R-HSA-2980766|reactome:R-HSA-2995383|refseq:XP_016874003.1|refseq:XP_016874004.1|dip:DIP-50395N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:JSfPqQhIXIFEXNQn1+I8v5zG+Hw9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q92754 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-937309|uniprotkb:B4DWK3|uniprotkb:O00685|uniprotkb:O00730|uniprotkb:Q86V30|uniprotkb:Q8IVB6|uniprotkb:Q9P1X2|ensembl:ENSP00000201031 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ap2c_human(display_long)|uniprotkb:TFAP2C(gene name)|psi-mi:TFAP2C(display_short)|uniprotkb:Activating enhancer-binding protein 2 gamma(gene name synonym)|uniprotkb:Transcription factor ERF-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_003213.1|ensembl:ENSP00000201031|ensembl:ENSG00000087510(gene)|ensembl:ENST00000201031(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008584"(male gonad development)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008123(Transcription factor AP-2 gamma)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|reactome:R-HSA-3232118|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:Q8FqfrkvHEOgtWrYKjCOBfeS8mM9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O00560 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q01664 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2514218|ensembl:ENSP00000204517|uniprotkb:O60409 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:tfap4_human(display_long)|uniprotkb:TFAP4(gene name)|psi-mi:TFAP4(display_short)|uniprotkb:Activating enhancer-binding protein 4(gene name synonym)|uniprotkb:BHLHC41(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000090447(gene)|ensembl:ENST00000204517(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|refseq:NP_003214.1|dip:DIP-53627N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:WNpFrsmcAWD2UAtTlQzXoUAmFU09606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q16576 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P55265 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9H165 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-765567|uniprotkb:Q86W14|uniprotkb:Q8WU92|uniprotkb:Q96JL6|uniprotkb:Q9H163|uniprotkb:Q9H164|uniprotkb:Q9H3G9|uniprotkb:Q9NWA7|uniprotkb:D6W5D7|uniprotkb:Q66LN6|ensembl:ENSP00000496168 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:bc11a_human(display_long)|uniprotkb:B-cell CLL/lymphoma 11A(gene name synonym)|uniprotkb:COUP-TF-interacting protein 1(gene name synonym)|uniprotkb:Ecotropic viral integration site 9 protein homolog(gene name synonym)|uniprotkb:BCL11A(gene name)|psi-mi:BCL11A(display_short)|uniprotkb:CTIP1(gene name synonym)|uniprotkb:EVI9(gene name synonym)|uniprotkb:KIAA1809(gene name synonym)|uniprotkb:ZNF856(gene name synonym)|uniprotkb:Zinc finger protein 856(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_060484.2|refseq:NP_075044.2|refseq:NP_612569.1|refseq:XP_011531211.1|refseq:XP_016859823.1|dip:DIP-45629N|ensembl:ENSG00000119866(gene)|ensembl:ENST00000642384(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:1903860"(negative regulation of dendrite extension)|go:"GO:1904800"(negative regulation of neuron remodeling)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H165|rcsb pdb:5VTB|rcsb pdb:6KI6|rcsb pdb:6U9Q|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:xASsLQWykg/7ZpyjLsQP8GlQ/H09606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8NCP5 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-5658292|uniprotkb:Q86VJ7|uniprotkb:Q6IPT8|uniprotkb:Q86XX5|intact:EBI-28972467 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zbt44_human(display_long)|uniprotkb:BTB/POZ domain-containing protein 15(gene name synonym)|uniprotkb:BTBD15(gene name synonym)|uniprotkb:ZNF851(gene name synonym)|uniprotkb:Zinc finger protein 851(gene name synonym)|uniprotkb:ZBTB44(gene name)|psi-mi:ZBTB44(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N mint:Q8NCP5|ensembl:ENST00000445008|ensembl:ENSP00000408079|ensembl:ENSG00000196323|ensembl:ENST00000525842|ensembl:ENSP00000433457|ensembl:ENST00000530205|ensembl:ENSP00000434177|refseq:NP_001288027.1|refseq:NP_001288028.1|interpro:IPR036236|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0003677"(DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_054874.3|refseq:XP_016873112.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:xewgUIEkS1YVch+LlFi+bSwFZ2Y9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8NDX6 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2602428|uniprotkb:A8K9M9|ensembl:ENSP00000409463 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zn740_human(display_long)|uniprotkb:ZNF740(gene name)|psi-mi:ZNF740(display_short)|uniprotkb:TB7(gene name synonym)|uniprotkb:OriLyt TD-element-binding protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001004304.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|ensembl:ENSG00000139651(gene)|ensembl:ENST00000416904(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:2i7f+rUftAUiFntFARDjwFBLfrs9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P31271 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-9995718|uniprotkb:A4D188|uniprotkb:O43371|intact:EBI-28985756|ensembl:ENSP00000497112 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:hxa13_human(display_long)|uniprotkb:HOXA13(gene name)|psi-mi:HOXA13(display_short)|uniprotkb:HOX1J(gene name synonym)|uniprotkb:Homeobox protein Hox-1J(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_000513.2|ensembl:ENSP00000497112|ensembl:ENSG00000106031(gene)|ensembl:ENST00000649031(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0030539"(male genitalia development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060442"(branching involved in prostate gland morphogenesis)|go:"GO:0060847"(endothelial cell fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001055"(positive regulation of mesenchymal cell apoptotic process)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|rcsb pdb:2L7Z - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:MAUzfek63ZVXbaWo9MOXMIFrn309606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q92900 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8IV63 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1058605|uniprotkb:Q502Y2|uniprotkb:Q9P2V8|uniprotkb:A8KA53|intact:EBI-1795523|uniprotkb:A6NEG5|ensembl:ENSP00000324636|ensembl:ENSP00000469880|ensembl:ENSP00000473171 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:vrk3_human(display_long)|uniprotkb:VRK3(gene name)|psi-mi:VRK3(display_short)|uniprotkb:Vaccinia-related kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein pseudokinase VRK3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001295349.1|refseq:NP_057524.3|refseq:NP_001020949.1|ensembl:ENSG00000105053(gene)|ensembl:ENST00000316763(transcript)|ensembl:ENST00000594948(transcript)|ensembl:ENST00000599538(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026870|rcsb pdb:2JII|reactome:R-HSA-202670|refseq:XP_005259028.1|refseq:XP_005259029.1|refseq:XP_006723300.1|refseq:XP_006723301.1|refseq:XP_011525325.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:eoBtIgSkVcOE5bw/By6UEqbiO/I9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9BQ39 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P29590 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O15060 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-9995672|uniprotkb:A7MD38|uniprotkb:Q9UD98|ensembl:ENSP00000300101 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zbt39_human(display_long)|uniprotkb:ZBTB39(gene name)|psi-mi:ZBTB39(display_short)|uniprotkb:KIAA0352(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_055645.1|ensembl:ENSG00000166860(gene)|ensembl:ENST00000300101(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:Av7NePVsCU1s3cJiVI5keFGiirA9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q14257 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q13547 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9UQR1 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2688184|uniprotkb:Q58EY5|uniprotkb:O43591|uniprotkb:O00389|uniprotkb:D3DN27|ensembl:ENSP00000420448|ensembl:ENSP00000353863|ensembl:ENSP00000419322|ensembl:ENSP00000420335|uniprotkb:Q6PJ98 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zn148_human(display_long)|uniprotkb:ZBP89(gene name synonym)|uniprotkb:Transcription factor ZBP-89(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 89(gene name synonym)|uniprotkb:ZNF148(gene name)|psi-mi:ZNF148(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_068799.2|ensembl:ENST00000360647(transcript)|ensembl:ENST00000484491(transcript)|ensembl:ENST00000485866(transcript)|ensembl:ENST00000492394(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006968"(cellular defense response)|go:"GO:0007276"(gamete generation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021762"(substantia nigra development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9UQR1|ensembl:ENSG00000163848(gene)|refseq:NP_001335353.1|refseq:NP_001335354.1|refseq:NP_001335355.1|refseq:NP_001335356.1|refseq:NP_001335357.1|refseq:NP_001335358.1|refseq:NP_001335359.1|refseq:NP_001335360.1|refseq:NP_001335361.1|refseq:NP_001335362.1|ensembl:ENSP00000353863|ensembl:ENSP00000420335|ensembl:ENSP00000420448|ensembl:ENSP00000419322 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:2H8lAaonZqAnCWDtUN8q55+03h49606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q92766 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1210379|uniprotkb:E2GM80|uniprotkb:E2GM81|uniprotkb:A2RRF5|uniprotkb:O75567|uniprotkb:O75568|uniprotkb:Q5VYB2|uniprotkb:Q6BEP5|uniprotkb:Q6BEP6|uniprotkb:Q6BEP8|uniprotkb:Q86SU2|uniprotkb:Q9Y474|ensembl:ENSP00000305560|ensembl:ENSP00000369265 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:rreb1_human(display_long)|uniprotkb:RREB1(gene name)|psi-mi:RREB1(display_short)|uniprotkb:FINB(gene name synonym)|uniprotkb:Raf-responsive zinc finger protein LZ321(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 1(gene name synonym)|uniprotkb:Finger protein in nuclear bodies(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:XP_011513097.1|refseq:NP_001003698.1|refseq:NP_001003699.1|refseq:NP_001003700.1|refseq:NP_001161816.1|refseq:XP_006715220.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSG00000124782(gene)|ensembl:ENST00000349384(transcript)|ensembl:ENST00000379933(transcript) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:BKnzSXiZmB0IL9opvk8w6WiDMU49606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q14151 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-352869|ensembl:ENSP00000252542|uniprotkb:Q8TB13|uniprotkb:B4DKG3|intact:EBI-2948582 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:safb2_human(display_long)|uniprotkb:SAFB2(gene name)|psi-mi:SAFB2(display_short)|uniprotkb:KIAA0138(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000130254(gene)|ensembl:ENST00000252542(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|interpro:IPR035979|go:"GO:0042802"(identical protein binding)|interpro:IPR036361|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|mint:Q14151|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034782|refseq:NP_055464.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:4/eQxEPzUXIuUuqP2ogEL+zY31g9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9HCE1 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q12948 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1175253|uniprotkb:Q86UP7|uniprotkb:Q9BYM1|uniprotkb:Q9NUE5|uniprotkb:Q9UDD0|uniprotkb:Q9UP06|ensembl:ENSP00000493906 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:foxc1_human(display_long)|uniprotkb:Forkhead-related protein FKHL7(gene name synonym)|uniprotkb:Forkhead-related transcription factor 3(gene name synonym)|uniprotkb:FOXC1(gene name)|psi-mi:FOXC1(display_short)|uniprotkb:FKHL7(gene name synonym)|uniprotkb:FREAC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENST00000645831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001654"(eye development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|ensembl:ENSG00000054598(gene)|go:"GO:0001822"(kidney development)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0021549"(cerebellum development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0008301"(DNA binding, bending)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:0060038"(cardiac muscle cell proliferation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR033067|go:"GO:0070098"(chemokine-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|mint:Q12948|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072010"(glomerular epithelium development)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902038"(positive regulation of hematopoietic stem cell differentiation)|go:"GO:1902257"(negative regulation of apoptotic process involved in outflow tract morphogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|ensembl:ENSP00000493906|refseq:NP_001444.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:+HuKwX8xMx86iCQW/a+vy/rWP389606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8IXT5 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-3044077|ensembl:ENSP00000382239|ensembl:ENSP00000427729|ensembl:ENSP00000428269|ensembl:ENSP00000429807|ensembl:ENSP00000430474|uniprotkb:A8MYB5 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:rb12b_human(display_long)|uniprotkb:RBM12B(gene name)|psi-mi:RBM12B(display_short)|uniprotkb:RNA-binding motif protein 12B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:XP_016868895.1|refseq:XP_016868896.1|refseq:XP_016868897.1|ensembl:ENSG00000183808(gene)|ensembl:ENST00000399300(transcript)|ensembl:ENST00000517700(transcript)|ensembl:ENST00000518597(transcript)|ensembl:ENST00000519109(transcript)|ensembl:ENST00000520560(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034588|interpro:IPR034858|interpro:IPR035979|refseq:XP_011515329.1|refseq:XP_011515330.1|refseq:XP_011515331.1|refseq:NP_976324.2|refseq:XP_005250972.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:WFJYO2tbSpgVmVVnSyFLn4O2+HM9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9UGU0 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9H2P0 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:XP_011527049.1|refseq:NP_056154.1|refseq:NP_852107.1|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881|ensembl:ENSG00000101126(gene)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|ensembl:ENST00000349014(transcript)|ensembl:ENST00000371602(transcript)|ensembl:ENST00000396029(transcript)|ensembl:ENST00000396032(transcript)|ensembl:ENST00000621696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9H2P0|refseq:XP_016883247.1|refseq:XP_016883248.1|refseq:NP_001334440.1|dip:DIP-47288N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q6NSZ9 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-9995630|uniprotkb:A4D290|uniprotkb:D6W5T5|uniprotkb:Q14C82|uniprotkb:Q14C99|uniprotkb:Q5EBM9|uniprotkb:Q6DJZ0|uniprotkb:Q6N032|uniprotkb:Q6ZML3|ensembl:ENSP00000334800|ensembl:ENSP00000377708 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zsc25_human(display_long)|uniprotkb:ZSCAN25(gene name)|psi-mi:ZSCAN25(display_short)|uniprotkb:ZNF498(gene name synonym)|uniprotkb:Zinc finger protein 498(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_660090.2|refseq:XP_005250251.1|refseq:XP_016867313.1|refseq:XP_011514207.1|refseq:XP_011514208.1|refseq:XP_011514209.1|ensembl:ENSG00000197037(gene)|ensembl:ENST00000334715(transcript)|ensembl:ENST00000394152(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|reactome:R-HSA-212436|refseq:XP_011514210.1|refseq:XP_016867314.1|refseq:XP_016867315.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:oMQQw4jg3xovE7lw8kMxWCDzF109606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P49959 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q7Z6I8 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-9995695|uniprotkb:D3DQA7|uniprotkb:Q86Y53|uniprotkb:Q8N1T9|ensembl:ENSP00000337044|ensembl:ENSP00000378427|ensembl:ENSP00000395764 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ce024_human(display_long)|uniprotkb:C5orf24(gene name)|psi-mi:C5orf24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001129058.1|refseq:NP_001287823.1|refseq:NP_689622.2|refseq:XP_005271946.1|refseq:XP_016864538.1|refseq:XP_016864539.1|ensembl:ENSG00000181904(gene)|ensembl:ENST00000338051(transcript)|ensembl:ENST00000394976(transcript)|ensembl:ENST00000435259(transcript)|interpro:IPR040419 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:Ye+nbD86YyjmFkryW2orfM3Wh4w9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8TF68 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-6115971|uniprotkb:O15407|uniprotkb:Q7Z722|uniprotkb:Q8N938|ensembl:ENSP00000354592|ensembl:ENSP00000380019 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zn384_human(display_long)|uniprotkb:ZNF384(gene name)|psi-mi:ZNF384(display_short)|uniprotkb:CAGH1(gene name synonym)|uniprotkb:CIZ(gene name synonym)|uniprotkb:NMP4(gene name synonym)|uniprotkb:TNRC1(gene name synonym)|uniprotkb:CAG repeat protein 1(gene name synonym)|uniprotkb:CAS-interacting zinc finger protein(gene name synonym)|uniprotkb:Nuclear matrix transcription factor 4(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENST00000319770|ensembl:ENSP00000321650|ensembl:ENSP00000354592|ensembl:ENSP00000380019|ensembl:ENST00000355772|ensembl:ENSP00000348018|refseq:NP_001035009.1|refseq:NP_001129206.1|refseq:NP_597733.2|refseq:XP_016874430.1|refseq:XP_016874431.1|refseq:XP_016874432.1|refseq:XP_016874438.1|refseq:XP_016874439.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8TF68|ensembl:ENSG00000126746(gene)|ensembl:ENST00000361959(transcript)|ensembl:ENST00000396801(transcript) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:6TO45205H9niXg8StUmIooVLC289606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P05549 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P51608 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P49790 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-286779|uniprotkb:Q5T9I7|intact:EBI-1237421|uniprotkb:E7EPX5|uniprotkb:Q4LE47|uniprotkb:Q7Z743|uniprotkb:B4DIK2|uniprotkb:F6QR24|ensembl:ENSP00000262077 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:nu153_human(display_long)|uniprotkb:Nucleoporin Nup153(gene name synonym)|uniprotkb:153 kDa nucleoporin(gene name synonym)|uniprotkb:NUP153(gene name)|psi-mi:NUP153(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSP00000262077|ensembl:ENST00000537253|ensembl:ENSP00000444029|ensembl:ENST00000613258|ensembl:ENSP00000478627|refseq:NP_005115.2|refseq:NP_001265138.1|refseq:NP_001265139.1|dip:DIP-38185N|ensembl:ENSG00000124789(gene)|ensembl:ENST00000262077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043657"(host cell)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046832"(negative regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013913(Nucleoporin, Nup153-like)|interpro:IPR018892|interpro:IPR026054|interpro:IPR036443|mint:P49790|rcsb pdb:2EBQ|rcsb pdb:2EBR|rcsb pdb:2EBV|rcsb pdb:2GQE|rcsb pdb:4U0C|rcsb pdb:4U0D|rcsb pdb:5TSV|rcsb pdb:5TSX|rcsb pdb:6AYA|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:rOax/ikcAu5fmDiCOauVr7Y/fzY9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q92769 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P78347 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9H444 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q96SI9 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-740355|uniprotkb:Q32NB9|uniprotkb:Q9BUE1|uniprotkb:Q9BXG4|uniprotkb:Q9H0B4|uniprotkb:Q9H7V1|uniprotkb:Q9NUK4|ensembl:ENSP00000321347|ensembl:ENSP00000415968 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:strbp_human(display_long)|uniprotkb:STRBP(gene name)|psi-mi:STRBP(display_short)|uniprotkb:SPNR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001164608.1|refseq:NP_060857.2|ensembl:ENSG00000165209(gene)|ensembl:ENST00000348403(transcript)|ensembl:ENST00000447404(transcript)|go:"GO:0002177"(manchette)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008017"(microtubule binding)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR030446|interpro:IPR043519|interpro:IPR044472|rcsb pdb:2DMY|refseq:XP_016870383.1|refseq:XP_016870384.1|refseq:XP_016870385.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:xVEZqCqBcH0MBB1Ar9SU+9Yhsbs9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P13010 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P19532 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1048957|uniprotkb:A8MZL6|uniprotkb:Q92757|uniprotkb:Q92758|uniprotkb:Q99964|uniprotkb:Q5JU74|intact:EBI-28988974|ensembl:ENSP00000314129 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:tfe3_human(display_long)|uniprotkb:TFE3(gene name)|psi-mi:TFE3(display_short)|uniprotkb:BHLHE33(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 33(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_006512.2|refseq:NP_001269071.1|ensembl:ENSP00000314129|ensembl:ENST00000493583|ensembl:ENSP00000476976|ensembl:ENSG00000068323(gene)|ensembl:ENST00000315869(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR021802|interpro:IPR024100|interpro:IPR031867|interpro:IPR036638|dip:DIP-50187N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:AQ735wtDaKEzjMlG6ZyiOBVo/kw9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P42167 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8WXX5 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P50402 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q6SPF0 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-8833536|uniprotkb:Q96IM4|uniprotkb:Q6PIS7|uniprotkb:Q6P0R3 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:samd1_human(display_long)|uniprotkb:SAMD1(gene name)|psi-mi:SAMD1(display_short)|uniprotkb:Atherin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N mint:Q6SPF0|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_612361.1|go:"GO:0005737"(cytoplasm)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:6LUI|rcsb pdb:6LUJ|rcsb pdb:6LUK|go:"GO:0003682"(chromatin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:Cav/ZfHiZJ1xCBI6jAYrzv+CmZ49606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O00148 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q86T24 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2515625|ensembl:ENSP00000314153|ensembl:ENSP00000450969|uniprotkb:Q7Z361|uniprotkb:Q8N3P0|uniprotkb:Q8IVP6|uniprotkb:O00319|uniprotkb:B2R5U6 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:kaiso_human(display_long)|uniprotkb:ZBTB33(gene name)|psi-mi:ZBTB33(display_short)|uniprotkb:KAISO(gene name synonym)|uniprotkb:ZNF348(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 33(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000177485(gene)|ensembl:ENST00000326624(transcript)|ensembl:ENST00000557385(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2LT7|rcsb pdb:3FKC|rcsb pdb:3M4T|rcsb pdb:3M8V|rcsb pdb:4F6M|rcsb pdb:4F6N|rcsb pdb:5VMU|rcsb pdb:5VMV|rcsb pdb:5VMW|rcsb pdb:5VMX|rcsb pdb:5VMY|rcsb pdb:5VMZ|rcsb pdb:6DF5|rcsb pdb:6DF8|rcsb pdb:6DF9|rcsb pdb:6DFA|rcsb pdb:6DFB|rcsb pdb:6DFC|rcsb pdb:6V8U|refseq:NP_001171671.1|refseq:NP_006768.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:nD+3FCTCYxUrXZXpBW5Co1V0CHc9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P09936 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9NUX5 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-752420|uniprotkb:O95018|uniprotkb:Q9H662|uniprotkb:Q9NW19|uniprotkb:Q9UG95|uniprotkb:Q5MJ36|ensembl:ENSP00000350249|ensembl:ENSP00000499290|ensembl:ENSP00000499476|ensembl:ENSP00000499546|ensembl:ENSP00000499635 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:pote1_human(display_long)|uniprotkb:POT1-like telomere end-binding protein(gene name synonym)|uniprotkb:POT1(gene name)|psi-mi:POT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001036059.1|refseq:NP_056265.2|refseq:XP_006715980.1|dip:DIP-29610N|ensembl:ENSG00000128513(gene)|ensembl:ENST00000357628(transcript)|ensembl:ENST00000653241(transcript)|ensembl:ENST00000655761(transcript)|ensembl:ENST00000664366(transcript)|ensembl:ENST00000668382(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0032202"(telomere assembly)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060383"(positive regulation of DNA strand elongation)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0061821"(telomeric D-loop binding)|go:"GO:0070187"(shelterin complex)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1905773"(8-hydroxy-2'-deoxyguanosine DNA binding)|go:"GO:1905774"(regulation of DNA helicase activity)|go:"GO:1905776"(positive regulation of DNA helicase activity)|go:"GO:1990955"(G-rich single-stranded DNA binding)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR032042|rcsb pdb:1XJV|rcsb pdb:3KJO|rcsb pdb:3KJP|rcsb pdb:5H65|rcsb pdb:5UN7|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:h/UEb6TNSNHVB4S0YRgS2oA4ydQ9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P49116 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q14152 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q06587 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O14929 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P24534 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9UGN5 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2795348|uniprotkb:Q8TEU4|uniprotkb:Q9NUV2|uniprotkb:Q9UMR4|uniprotkb:Q9Y6C8|ensembl:ENSP00000250416 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:parp2_human(display_long)|uniprotkb:PARP2(gene name)|psi-mi:PARP2(display_short)|uniprotkb:ADPRT2(gene name synonym)|uniprotkb:ADPRTL2(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 2"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 2(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 2(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP2(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001036083.1|refseq:NP_005475.2|ensembl:ENSG00000129484(gene)|ensembl:ENST00000250416(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016570"(histone modification)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036616|go:"GO:0005634"(nucleus)|interpro:IPR036930|mint:Q9UGN5|rcsb pdb:3KCZ|rcsb pdb:3KJD|rcsb pdb:4PJV|rcsb pdb:4TVJ|rcsb pdb:4ZZX|rcsb pdb:4ZZY|rcsb pdb:5D5K|rcsb pdb:5DSY|rcsb pdb:6F1K|rcsb pdb:6F5B|rcsb pdb:6F5F|rcsb pdb:6TX3|rcsb pdb:6USJ|rcsb pdb:6X0L|rcsb pdb:6X0M|rcsb pdb:6X0N|rcsb pdb:7AEO|reactome:R-HSA-110362|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|dip:DIP-48934N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:0sLs7K5dQNmmhUwnGT9UIvparjU9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9Y4W2 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q6NT76 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P14373 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9H2Z4 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-9995757|uniprotkb:Q5VZV8|ensembl:ENSP00000345147 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:nkx24_human(display_long)|uniprotkb:NKX2-4(gene name)|psi-mi:NKX2-4(display_short)|uniprotkb:NKX2D(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_149416.1|ensembl:ENSG00000125816(gene)|ensembl:ENST00000351817(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030154"(cell differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:DYK4ryzJaN1B6m3q09xe45yj9k89606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q12800 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-717422|uniprotkb:Q12801|uniprotkb:Q9UD77|uniprotkb:A8K5E9|uniprotkb:Q9UD75|ensembl:ENSP00000257915 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:tfcp2_human(display_long)|uniprotkb:Transcription factor LSF(gene name synonym)|uniprotkb:SAA3 enhancer factor(gene name synonym)|uniprotkb:TFCP2(gene name)|psi-mi:TFCP2(display_short)|uniprotkb:LSF(gene name synonym)|uniprotkb:SEF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001166923.1|refseq:NP_001166924.1|refseq:NP_005644.2|ensembl:ENSG00000135457(gene)|ensembl:ENST00000257915(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR007604(CP2 transcription factor)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037599|interpro:IPR041418|mint:Q12800 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:M7mQ08NDYxuawmUEKRgjSdIr+Og9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O94776 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9NWH9 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2814558|uniprotkb:A8K5V8|uniprotkb:Q6ZNF2|uniprotkb:B2RTX3|uniprotkb:Q9H7C3|uniprotkb:Q658J7|uniprotkb:Q52MB3|uniprotkb:Q9H8U9|uniprotkb:Q86TK6|uniprotkb:Q2VPK7|ensembl:ENSP00000369887 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:sltm_human(display_long)|uniprotkb:SLTM(gene name)|psi-mi:SLTM(display_short)|uniprotkb:MET(gene name synonym)|uniprotkb:Modulator of estrogen-induced transcription(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:XP_006720753.1|refseq:NP_079031.2|refseq:NP_001013865.1|refseq:XP_016878069.1|ensembl:ENSG00000137776(gene)|ensembl:ENST00000380516(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034780|interpro:IPR035979|interpro:IPR036361|mint:Q9NWH9 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:/B0FdPpFi/TvMq9aGjuLOQ3zIuo9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P49711 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q5T5X7 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1211496|uniprotkb:A2RRH2|uniprotkb:Q9HCL9|ensembl:ENSP00000358038|ensembl:ENSP00000411268 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:bend3_human(display_long)|uniprotkb:BEND3(gene name)|psi-mi:BEND3(display_short)|uniprotkb:KIAA1553(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:XP_005267136.1|refseq:XP_005267137.1|refseq:NP_001073919.1|refseq:XP_011534307.1|refseq:XP_016866627.1|ensembl:ENSG00000178409(gene)|ensembl:ENST00000369042(transcript)|ensembl:ENST00000429433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000792"(heterochromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1903580"(positive regulation of ATP metabolic process)|interpro:IPR018379|interpro:IPR033583|rcsb pdb:5JNO - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:W+UmsinDpvnD5wV9MZI5YWywK6U9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8WUY1 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1170414|uniprotkb:Q8NBN2|uniprotkb:Q9NYI2|uniprotkb:B2RDN6|intact:EBI-2563242|ensembl:ENSP00000338607 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:them6_human(display_long)|uniprotkb:THEM6(gene name)|psi-mi:THEM6(display_short)|uniprotkb:C8orf55(gene name synonym)|uniprotkb:Mesenchymal stem cell protein DSCD75(gene name synonym)|uniprotkb:Thioesterase superfamily member 6(gene name synonym)|uniprotkb:PSEC0098(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_057731.1|ensembl:ENSG00000130193(gene)|ensembl:ENST00000336138(transcript)|go:"GO:0005576"(extracellular region)|interpro:IPR029069 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:VCZRUm2WiwLdWnKB8jTuOvLy+4A9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8N0Y2 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-6660528|ensembl:ENSP00000338860|uniprotkb:Q9NUU1|uniprotkb:Q8WU35|uniprotkb:Q8TEQ9 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zn444_human(display_long)|uniprotkb:ZNF444(gene name)|psi-mi:ZNF444(display_short)|uniprotkb:EZF2(gene name synonym)|uniprotkb:Endothelial zinc finger protein 2(gene name synonym)|uniprotkb:ZSCAN17(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000167685(gene)|ensembl:ENST00000337080(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_011525370.1|refseq:NP_001240721.1|refseq:NP_060807.2|refseq:XP_005259091.1|refseq:XP_005259092.1|refseq:XP_005259093.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:mtsW9JRIoWkvBjEsovYO7sKkcos9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O60264 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8WXI9 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q14839 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8NC56 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-6149955|uniprotkb:Q5T972|uniprotkb:Q5T974|uniprotkb:B4DVH5|uniprotkb:E7EVT2|ensembl:ENSP00000293760|ensembl:ENSP00000478539 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:lemd2_human(display_long)|uniprotkb:LEMD2(gene name)|psi-mi:LEMD2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001335638.1|refseq:NP_851853.1|refseq:NP_001137416.1|ensembl:ENSG00000161904(gene)|ensembl:ENST00000293760(transcript)|ensembl:ENST00000614475(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022008"(neurogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060914"(heart formation)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR018996|interpro:IPR034994|interpro:IPR041885|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9668328 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:mDTKCvVjxMtw3uYpitoTXSZHAYY9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O00541 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1053271|uniprotkb:Q6IC29|ensembl:ENSP00000346725 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:pesc_human(display_long)|uniprotkb:PES1(gene name)|psi-mi:PES1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001230154.1|refseq:NP_055118.1|ensembl:ENSG00000100029(gene)|ensembl:ENST00000354694(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:2EP8|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:Nq1SJ37kJfe+vF9zmNASz1gnbfY9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O94880 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2680164|uniprotkb:B4DI82|uniprotkb:A7MCZ3|ensembl:ENSP00000385795 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:phf14_human(display_long)|uniprotkb:KIAA0783(gene name synonym)|uniprotkb:PHF14(gene name)|psi-mi:PHF14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_055475.2|ensembl:ENSG00000106443(gene)|ensembl:ENST00000403050(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:O94880 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:5x6w7H9UP9mf4xk3lXYfAHaIo2Q9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q6FI13 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9P258 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-352547|uniprotkb:Q8IVL9|uniprotkb:Q9BSN6|uniprotkb:Q9NPV8|ensembl:ENSP00000364582|ensembl:ENSP00000364585|ensembl:ENSP00000486099|ensembl:ENSP00000486447 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:rcc2_human(display_long)|uniprotkb:RCC2(gene name)|psi-mi:RCC2(display_short)|uniprotkb:KIAA1470(gene name synonym)|uniprotkb:TD60(gene name synonym)|uniprotkb:Telophase disk protein of 60 kDa(gene name synonym)|uniprotkb:RCC1-like protein TD-60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001129676.1|refseq:NP_061185.1|ensembl:ENSG00000179051(gene)|ensembl:ENSG00000281540(gene)|ensembl:ENST00000375433(transcript)|ensembl:ENST00000375436(transcript)|ensembl:ENST00000628984(transcript)|ensembl:ENST00000631021(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051301"(cell division)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072356"(chromosome passenger complex localization to kinetochore)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR028641|mint:Q9P258|rcsb pdb:5GWN|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:z9+0avftBLs4Q3ODFHLEmJtd57A9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P24468 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2795198|uniprotkb:B6ZGU1|uniprotkb:Q03754|uniprotkb:B4DQJ2|uniprotkb:Q3KQR7|ensembl:ENSP00000377721 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:cot2_human(display_long)|uniprotkb:NR2F2(gene name)|psi-mi:NR2F2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:TFCOUP2(gene name synonym)|uniprotkb:COUP transcription factor II(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group F member 2(gene name synonym)|uniprotkb:Apolipoprotein A-I regulatory protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_066285.1|refseq:NP_001138627.1|refseq:NP_001138628.1|refseq:NP_001138629.1|ensembl:ENSG00000185551(gene)|ensembl:ENST00000394166(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008585"(female gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0009956"(radial pattern formation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032355"(response to estradiol)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060173"(limb development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:3CJW|reactome:R-HSA-381340|dip:DIP-29713N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:XsZyqUr06sQQaD3oXAA3IEa6Dug9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P52701 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P12956 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P62191 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9HB71 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1047302|uniprotkb:O60666|ensembl:ENSP00000356652|uniprotkb:B2ZWH2|uniprotkb:Q5R371|uniprotkb:B3KSF1|uniprotkb:Q5R370 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:cybp_human(display_long)|uniprotkb:Siah-interacting protein(gene name synonym)|uniprotkb:S100A6-binding protein(gene name synonym)|uniprotkb:CACYBP(gene name)|psi-mi:CACYBP(display_short)|uniprotkb:S100A6BP(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:PNAS-107(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR015120(Siah interacting protein, N terminal)|interpro:IPR037201|interpro:IPR037893|mint:Q9HB71|rcsb pdb:1X5M|rcsb pdb:2A25|rcsb pdb:2A26|go:"GO:0071277"(cellular response to calcium ion)|refseq:NP_001007215.1|refseq:NP_055227.1|ensembl:ENSG00000116161(gene)|ensembl:ENST00000367679(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0015631"(tubulin binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|refseq:XP_016856535.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:mvv1o19mLHBS3FDnATyOFsDoZvk9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P05412 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9UIS9 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-867196|uniprotkb:K7ELI2|uniprotkb:Q9UNZ9|uniprotkb:K7EQZ4|uniprotkb:K7ESN0|uniprotkb:A4UTZ0|uniprotkb:O15248|uniprotkb:O95241|uniprotkb:Q7Z7B5|uniprotkb:Q8N4W4|uniprotkb:Q9UNZ6|uniprotkb:Q9UNZ7|uniprotkb:Q9UNZ8|uniprotkb:B4DXJ5|uniprotkb:E9PEC5|intact:EBI-10977266|ensembl:ENSP00000269468|ensembl:ENSP00000372407|ensembl:ENSP00000467017 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:mbd1_human(display_long)|uniprotkb:CXXC3(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD1(gene name synonym)|uniprotkb:Protein containing methyl-CpG-binding domain 1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 3(gene name synonym)|uniprotkb:MBD1(gene name)|psi-mi:MBD1(display_short)|uniprotkb:PCM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001191065.1|refseq:NP_001191068.1|refseq:NP_001191071.1|refseq:NP_001191072.1|refseq:NP_001191080.1|refseq:NP_002375.1|refseq:NP_056669.2|refseq:NP_056670.2|refseq:NP_056671.2|refseq:NP_056723.2|refseq:XP_011524295.1|refseq:XP_016881249.1|refseq:XP_016881259.1|refseq:XP_016881260.1|refseq:XP_016881265.1|refseq:XP_011524296.1|refseq:XP_011524308.1|refseq:NP_001191066.1|refseq:NP_001191067.1|refseq:NP_001191069.1|refseq:NP_001191070.1|refseq:XP_005258328.1|ensembl:ENSG00000141644(gene)|ensembl:ENST00000269468(transcript)|ensembl:ENST00000382948(transcript)|ensembl:ENST00000591416(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR016177(DNA-binding, integrase-type)|mint:Q9UIS9|rcsb pdb:1D9N|rcsb pdb:1IG4|rcsb pdb:4D4W|rcsb pdb:5W9Q|rcsb pdb:6D1T|reactome:R-HSA-3899300 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:I6StIYNuO8jT6ZR1YxoZnzDrP/I9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P18887 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-947466|uniprotkb:Q9HCB1|uniprotkb:Q6IBS4|ensembl:ENSP00000262887 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:xrcc1_human(display_long)|uniprotkb:XRCC1(gene name)|psi-mi:XRCC1(display_short)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_006288.2|dip:DIP-39067N|ensembl:ENSG00000073050(gene)|ensembl:ENST00000262887(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904877"(positive regulation of DNA ligase activity)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990599"(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:P18887|rcsb pdb:1CDZ|rcsb pdb:1XNA|rcsb pdb:1XNT|rcsb pdb:2D8M|rcsb pdb:2W3O|rcsb pdb:3K75|rcsb pdb:3K77|rcsb pdb:3LQC|rcsb pdb:5E6Q|rcsb pdb:5W7X|rcsb pdb:5W7Y|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:96hETrBzHYhHX9FC5dZpKnFcjDg9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q8IX01 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-949116|ensembl:ENSP00000337926|ensembl:ENSP00000389380|ensembl:ENSP00000472286|uniprotkb:O15071|uniprotkb:O60369|uniprotkb:Q5JPH7|uniprotkb:Q8WUF7|uniprotkb:C9JI71 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:sugp2_human(display_long)|uniprotkb:Arginine/serine-rich-splicing factor 14(gene name synonym)|uniprotkb:SUGP2(gene name)|psi-mi:SUGP2(display_short)|uniprotkb:KIAA0365(gene name synonym)|uniprotkb:SFRS14(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000064607(gene)|ensembl:ENST00000337018(transcript)|ensembl:ENST00000452918(transcript)|ensembl:ENST00000601879(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR035967|interpro:IPR040169|mint:Q8IX01|rcsb pdb:1X4P|refseq:NP_001017392.2|refseq:NP_055699.2|refseq:XP_016881626.1|refseq:NP_001308626.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:hN1zWaoMMufKCQNO9VQ8NPiN0hI9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P49916 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1753381|intact:EBI-1058758|uniprotkb:Q16714|uniprotkb:Q6NVK3|ensembl:ENSP00000367787|uniprotkb:E5KLB5|uniprotkb:E5KLB6 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:dnli3_human(display_long)|uniprotkb:LIG3(gene name)|psi-mi:LIG3(display_short)|uniprotkb:DNA ligase III(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002302.2|refseq:NP_039269.2|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0070421"(DNA ligase III-XRCC1 complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090298"(negative regulation of mitochondrial DNA replication)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR031916|interpro:IPR036420|interpro:IPR036599|interpro:IPR036957|mint:P49916|rcsb pdb:1IMO|rcsb pdb:1IN1|rcsb pdb:1UW0|rcsb pdb:3L2P|rcsb pdb:3PC7|rcsb pdb:3PC8|rcsb pdb:3QVG|rcsb pdb:6WH1|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210|ensembl:ENSG00000005156(gene)|ensembl:ENST00000378526(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006288"(base-excision repair, DNA ligation)|go:"GO:0006302"(double-strand break repair)|refseq:XP_016880113.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:+GqYPnth9+VqCoh1TvPG4yEDLeo9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9HCD5 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2863498|uniprotkb:Q9H1F2|uniprotkb:Q6HA99|uniprotkb:Q9H2T2|uniprotkb:B2RTV9|uniprotkb:Q9H4Y9|uniprotkb:E1P5R0|ensembl:ENSP00000290231 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ncoa5_human(display_long)|uniprotkb:NCOA5(gene name)|psi-mi:NCOA5(display_short)|uniprotkb:KIAA1637(gene name synonym)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_066018.1|ensembl:ENSG00000124160(gene)|ensembl:ENST00000290231(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q9HCD5|rcsb pdb:1V95|rcsb pdb:2J7X|rcsb pdb:2J7Y|rcsb pdb:4ZI1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:OxiZZWrvRqepYlZiuTR4RqZWn1A9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q16658 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-351076|uniprotkb:Q96IH1|uniprotkb:A6NI89|uniprotkb:Q96IC5|uniprotkb:Q9BRF1|uniprotkb:B2RE97|ensembl:ENSP00000371798 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:fscn1_human(display_long)|uniprotkb:FSCN1(gene name)|psi-mi:FSCN1(display_short)|uniprotkb:FAN1(gene name synonym)|uniprotkb:HSN(gene name synonym)|uniprotkb:SNL(gene name synonym)|uniprotkb:Singed-like protein(gene name synonym)|uniprotkb:55 kDa actin-bundling protein(gene name synonym)|uniprotkb:p55(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0044393"(microspike)|go:"GO:0045296"(cadherin binding)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146|mint:Q16658|rcsb pdb:1DFC|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030035"(microspike assembly)|rcsb pdb:3LLP|refseq:NP_003079.1|ensembl:ENSG00000075618(gene)|ensembl:ENST00000382361(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008144"(obsolete drug binding)|rcsb pdb:3P53|rcsb pdb:4GOV|rcsb pdb:4GOY|rcsb pdb:4GP3|rcsb pdb:6B0T|rcsb pdb:6I0Z|rcsb pdb:6I10|rcsb pdb:6I11|rcsb pdb:6I12|rcsb pdb:6I13|rcsb pdb:6I14|rcsb pdb:6I15|rcsb pdb:6I16|rcsb pdb:6I17|rcsb pdb:6I18|reactome:R-HSA-6785807|rcsb pdb:4GP0|dip:DIP-33171N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:yc9EJDCKGJGGEcEueR/yAY/fxRg9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P13489 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q13557 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-351018|intact:EBI-1642546|uniprotkb:Q52PK4|uniprotkb:Q59G21|uniprotkb:Q8N553|uniprotkb:Q9UGH6|uniprotkb:Q9UQE9|uniprotkb:A8MVS8|ensembl:ENSP00000339740|ensembl:ENSP00000507073 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:kcc2d_human(display_long)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)|uniprotkb:CAMKD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001212.2|refseq:NP_742112.1|refseq:NP_742113.1|refseq:NP_742125.1|refseq:NP_742126.1|refseq:NP_742127.1|refseq:NP_001308495.1|refseq:NP_001308502.1|refseq:NP_001308509.1|refseq:NP_001308518.1|ensembl:ENSG00000145349(gene)|ensembl:ENST00000342666(transcript)|ensembl:ENST00000683023(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031432"(titin binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901725"(regulation of histone deacetylase activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13557|rcsb pdb:2VN9|rcsb pdb:2W2C|rcsb pdb:2WEL|rcsb pdb:3GP2|rcsb pdb:5VLO|rcsb pdb:6AYW|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|interpro:IPR032710|refseq:XP_011530591.1|refseq:XP_011530593.1|dip:DIP-33129N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q15424 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-348298|ensembl:ENSP00000292123|uniprotkb:O60406|uniprotkb:B7Z5B6|uniprotkb:F5H0H3|uniprotkb:Q59HH8|uniprotkb:A0AV56|uniprotkb:B7ZLP6 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:safb1_human(display_long)|uniprotkb:SAFB(gene name)|psi-mi:SAFB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HET(gene name synonym)|uniprotkb:SAFB1(gene name synonym)|uniprotkb:HSP27 estrogen response element-TATA box-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030496"(midbody)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000160633(gene)|interpro:IPR034781|interpro:IPR035979|ensembl:ENST00000292123(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|interpro:IPR036361|mint:Q15424|reactome:R-HSA-3899300|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|refseq:NP_002958.2|refseq:NP_001307500.1|refseq:NP_001307501.1|refseq:NP_001188269.1|refseq:NP_001188267.1|refseq:NP_001188268.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:Y31we6crSBL4G6uviNAfXyX0xfM9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q92522 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P19784 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P42285 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9C0K0 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-6597578|intact:EBI-28967428|ensembl:ENSP00000349723|uniprotkb:Q9H162 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:bc11b_human(display_long)|uniprotkb:BCL11B(gene name)|psi-mi:BCL11B(display_short)|uniprotkb:CTIP2(gene name synonym)|uniprotkb:RIT1(gene name synonym)|uniprotkb:B-cell CLL/lymphoma 11B(gene name synonym)|uniprotkb:COUP-TF-interacting protein 2(gene name synonym)|uniprotkb:Radiation-induced tumor suppressor gene 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N ensembl:ENST00000345514|ensembl:ENSP00000280435|ensembl:ENSP00000349723|ensembl:ENSG00000127152(gene)|ensembl:ENST00000357195(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043368"(positive T cell selection)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0071678"(olfactory bulb axon guidance)|go:"GO:0097535"(lymphoid lineage cell migration into thymus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9C0K0|refseq:NP_075049.1|refseq:NP_612808.1|refseq:NP_001269166.1|refseq:NP_001269167.1|dip:DIP-44025N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:qwv1arb47L+4NtLkdHByglThsqs9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P54198 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-372342|uniprotkb:Q05BU9|uniprotkb:Q8IXN2|ensembl:ENSP00000263208 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:hira_human(display_long)|uniprotkb:HIRA(gene name)|psi-mi:HIRA(display_short)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)|uniprotkb:DGCR1(gene name synonym)|uniprotkb:HIR(gene name synonym)|uniprotkb:TUPLE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_003316.3|dip:DIP-29240N|ensembl:ENSG00000100084(gene)|ensembl:ENST00000263208(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:P54198|rcsb pdb:2I32|rcsb pdb:5YJE|reactome:R-HSA-2559584 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:en6l6z4CNWhF4Wlj5ou4DDTfETg9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:O15015 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-745608|uniprotkb:Q8IVD8|ensembl:ENSP00000300850 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:zn646_human(display_long)|uniprotkb:KIAA0296(gene name synonym)|uniprotkb:ZNF646(gene name)|psi-mi:ZNF646(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_055514.3|refseq:XP_011544292.1|ensembl:ENSG00000167395(gene)|ensembl:ENST00000300850(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_005255767.1|refseq:XP_005255768.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:LLCOZY29R+2cHozH65lymJNIjRU9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P53621 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:P51648 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q13330 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-714236|uniprotkb:Q8NFI8|uniprotkb:Q96GI8|uniprotkb:A5PLK4|intact:EBI-28976623|ensembl:ENSP00000333633|uniprotkb:Q86SW2 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:mta1_human(display_long)|uniprotkb:MTA1(gene name)|psi-mi:MTA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:NP_001190187.1|refseq:NP_004680.2|ensembl:ENSP00000333633|ensembl:ENST00000405646|ensembl:ENSP00000384180|ensembl:ENST00000438610|ensembl:ENSP00000393438|ensembl:ENSG00000182979(gene)|ensembl:ENST00000331320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q13330|rcsb pdb:4BKX|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:5FXY|rcsb pdb:5ICN|rcsb pdb:6G16|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AO8|go:"GO:0045475"(locomotor rhythm)|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-3214815|dip:DIP-41751N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:nDDSb5B6YCbq5/6qvgtnUWtP23M9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14862 uniprotkb:Q9H5V7 intact:EBI-6253193|ensembl:ENSP00000357112|uniprotkb:A8K7M7|uniprotkb:Q5T3V9|uniprotkb:Q96FG9 intact:EBI-2685636|uniprotkb:B3KVH7|uniprotkb:Q9H2T0|uniprotkb:D3DRE7|ensembl:ENSP00000357881|ensembl:ENSP00000478056 psi-mi:aim2_human(display_long)|uniprotkb:AIM2(gene name)|psi-mi:AIM2(display_short)|uniprotkb:Absent in melanoma 2(gene name synonym) psi-mi:ikzf5_human(display_long)|uniprotkb:ZNFN1A5(gene name synonym)|uniprotkb:Ikaros family zinc finger protein 5(gene name synonym)|uniprotkb:IKZF5(gene name)|psi-mi:IKZF5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995694|imex:IM-23523-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4O7Q|rcsb pdb:6MB2|rcsb pdb:7K3R|reactome:R-HSA-844615|rcsb pdb:3VD8|ensembl:ENSG00000163568(gene)|ensembl:ENST00000368130(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044546"(NLRP3 inflammasome complex assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070269"(pyroptosis)|go:"GO:0097169"(AIM2 inflammasome complex)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:O14862|rcsb pdb:3RN2|rcsb pdb:3RN5|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_004824.1|refseq:XP_016858337.1|dip:DIP-59741N refseq:XP_006718010.1|refseq:NP_001258769.1|interpro:IPR036236|ensembl:ENSG00000095574(gene)|ensembl:ENST00000368886(transcript)|ensembl:ENST00000617859(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:XP_016872039.1|refseq:XP_016872040.1|refseq:XP_016872041.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:3TN0Sqyw7NrquK9pax1srmuEEJk9606 rogid:FnFi6hRZzKnYW/G3ApvexkOXcNo9606 intact-crc:493E56D016D8A2C9|rigid:v5HceQ1LjbmQ43o7J2UY5Pwzrg0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q14676 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O60934 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q92878 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q7Z6Z7 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UPW6 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N - - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O75487 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-3050469|uniprotkb:B4E2C0|ensembl:ENSP00000359864|uniprotkb:B2R6J7|uniprotkb:Q9UPD9|uniprotkb:Q96L43|uniprotkb:Q9NU08|uniprotkb:Q6ZMA6|uniprotkb:Q9UJN1 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:gpc4_human(display_long)|uniprotkb:GPC4(gene name)|psi-mi:GPC4(display_short)|uniprotkb:K-glypican(gene name synonym)|uniprotkb:UNQ474/PRO937(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000076716(gene)|ensembl:ENST00000370828(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009966"(regulation of signal transduction)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|mint:O75487|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1904929"(coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001863(Glypican)|interpro:IPR019803|interpro:IPR031180|go:"GO:0016055"(Wnt signaling pathway)|refseq:NP_001439.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:6IC3ItqIRoNTmnS+hi/U34DlXN09606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9Y462 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2849152|uniprotkb:Q9Y4J6|uniprotkb:Q6NX42|uniprotkb:B4DSV4|ensembl:ENSP00000276123|ensembl:ENSP00000362260 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:zn711_human(display_long)|uniprotkb:ZNF711(gene name)|psi-mi:ZNF711(display_short)|uniprotkb:CMPX1(gene name synonym)|uniprotkb:ZNF6(gene name synonym)|uniprotkb:Zinc finger protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:XP_011529326.1|refseq:XP_011529328.1|refseq:NP_068838.3|refseq:XP_005262243.1|refseq:XP_005262244.1|refseq:XP_005262245.1|refseq:XP_005262246.1|refseq:NP_001317503.1|refseq:XP_016885294.1|refseq:XP_016885295.1|refseq:XP_016885296.1|refseq:XP_016885297.1|refseq:XP_016885298.1|ensembl:ENSG00000147180(gene)|ensembl:ENST00000276123(transcript)|ensembl:ENST00000373165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR006794(Zfx / Zfy transcription activation region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:+D8I1UK1AkHcgA4oKgk04+/Spvg9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9HCD5 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2863498|uniprotkb:Q9H1F2|uniprotkb:Q6HA99|uniprotkb:Q9H2T2|uniprotkb:B2RTV9|uniprotkb:Q9H4Y9|uniprotkb:E1P5R0|ensembl:ENSP00000290231 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ncoa5_human(display_long)|uniprotkb:NCOA5(gene name)|psi-mi:NCOA5(display_short)|uniprotkb:KIAA1637(gene name synonym)|uniprotkb:Coactivator independent of AF-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_066018.1|ensembl:ENSG00000124160(gene)|ensembl:ENST00000290231(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q9HCD5|rcsb pdb:1V95|rcsb pdb:2J7X|rcsb pdb:2J7Y|rcsb pdb:4ZI1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:OxiZZWrvRqepYlZiuTR4RqZWn1A9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9Y4B6 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|intact:EBI-2559078|intact:EBI-28988191|ensembl:ENSP00000393183|ensembl:ENSP00000506880 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|ensembl:ENST00000335891|ensembl:ENSP00000338857|ensembl:ENSP00000393183|ensembl:ENST00000504652|ensembl:ENSP00000421724|ensembl:ENSP00000506880|ensembl:ENSG00000145041(gene)|ensembl:ENST00000423656(transcript)|ensembl:ENST00000684031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990244"("histone kinase activity (H2A-T120 specific)")|go:"GO:1990245"(histone H2A-T120 phosphorylation)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4P7I|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|dip:DIP-47048N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P16403 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q14980 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P10412 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-358163|uniprotkb:Q4VB25|ensembl:ENSP00000307705 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:h14_human(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1F4(gene name synonym)|uniprotkb:HIST1H1E(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_005312.1|rcsb pdb:6H8P|rcsb pdb:7K5Y|rcsb pdb:7K63|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10412|rcsb pdb:3TZD|rcsb pdb:5JJZ|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000168298(gene)|ensembl:ENST00000304218(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:yT8wBbspLLR8G3DrgpFeWEOPgac9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P49916 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1753381|intact:EBI-1058758|uniprotkb:Q16714|uniprotkb:Q6NVK3|ensembl:ENSP00000367787|uniprotkb:E5KLB5|uniprotkb:E5KLB6 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:dnli3_human(display_long)|uniprotkb:LIG3(gene name)|psi-mi:LIG3(display_short)|uniprotkb:DNA ligase III(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_002302.2|refseq:NP_039269.2|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0070421"(DNA ligase III-XRCC1 complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090298"(negative regulation of mitochondrial DNA replication)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR031916|interpro:IPR036420|interpro:IPR036599|interpro:IPR036957|mint:P49916|rcsb pdb:1IMO|rcsb pdb:1IN1|rcsb pdb:1UW0|rcsb pdb:3L2P|rcsb pdb:3PC7|rcsb pdb:3PC8|rcsb pdb:3QVG|rcsb pdb:6WH1|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210|ensembl:ENSG00000005156(gene)|ensembl:ENST00000378526(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006288"(base-excision repair, DNA ligation)|go:"GO:0006302"(double-strand break repair)|refseq:XP_016880113.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:+GqYPnth9+VqCoh1TvPG4yEDLeo9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P33991 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-374938|uniprotkb:Q8NEH1|uniprotkb:Q99658|ensembl:ENSP00000262105|ensembl:ENSP00000496964 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:mcm4_human(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:CDC21(gene name synonym)|uniprotkb:CDC21 homolog(gene name synonym)|uniprotkb:P1-CDC21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_005905.2|refseq:NP_877423.1|ensembl:ENSG00000104738(gene)|ensembl:ENST00000262105(transcript)|ensembl:ENST00000649973(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33991|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31729N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:emFkamsHmwBPzoJnPcaL4SaqAlU9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P31271 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-9995718|uniprotkb:A4D188|uniprotkb:O43371|intact:EBI-28985756|ensembl:ENSP00000497112 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:hxa13_human(display_long)|uniprotkb:HOXA13(gene name)|psi-mi:HOXA13(display_short)|uniprotkb:HOX1J(gene name synonym)|uniprotkb:Homeobox protein Hox-1J(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_000513.2|ensembl:ENSP00000497112|ensembl:ENSG00000106031(gene)|ensembl:ENST00000649031(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0030539"(male genitalia development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0048839"(inner ear development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060442"(branching involved in prostate gland morphogenesis)|go:"GO:0060847"(endothelial cell fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001055"(positive regulation of mesenchymal cell apoptotic process)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|rcsb pdb:2L7Z - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:MAUzfek63ZVXbaWo9MOXMIFrn309606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9NPG3 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2880187|ensembl:ENSP00000262376|ensembl:ENSP00000379894|uniprotkb:B7Z6D3|uniprotkb:Q13079|uniprotkb:Q9P1P7|uniprotkb:D3DUE8 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ubn1_human(display_long)|uniprotkb:UBN1(gene name)|psi-mi:UBN1(display_short)|uniprotkb:HIRA-binding protein(gene name synonym)|uniprotkb:Protein VT4(gene name synonym)|uniprotkb:Ubiquitously expressed nuclear protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000118900(gene)|ensembl:ENST00000262376(transcript)|ensembl:ENST00000396658(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026936|interpro:IPR026947|mint:Q9NPG3|rcsb pdb:4ZBJ|reactome:R-HSA-2559584|go:"GO:0005654"(nucleoplasm)|refseq:NP_001072982.1|refseq:XP_016878678.1|refseq:NP_001275585.1|ensembl:ENSP00000262376|ensembl:ENSP00000379894|ensembl:ENST00000590769|ensembl:ENSP00000468740 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:IT0lTmzNcbWFQVVD5DfATSqxjwg9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q16576 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P12956 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P54198 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-372342|uniprotkb:Q05BU9|uniprotkb:Q8IXN2|ensembl:ENSP00000263208 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:hira_human(display_long)|uniprotkb:HIRA(gene name)|psi-mi:HIRA(display_short)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)|uniprotkb:DGCR1(gene name synonym)|uniprotkb:HIR(gene name synonym)|uniprotkb:TUPLE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_003316.3|dip:DIP-29240N|ensembl:ENSG00000100084(gene)|ensembl:ENST00000263208(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:P54198|rcsb pdb:2I32|rcsb pdb:5YJE|reactome:R-HSA-2559584 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:en6l6z4CNWhF4Wlj5ou4DDTfETg9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UQ35 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1050142|uniprotkb:A6NKB9|uniprotkb:Q9UHA8|uniprotkb:Q9UQ36|uniprotkb:Q9UQ37|uniprotkb:Q9UQ38|uniprotkb:Q9UQ40|uniprotkb:O15038|uniprotkb:O94803|uniprotkb:Q6NSL3|uniprotkb:Q6PIM3|uniprotkb:Q6PK40|uniprotkb:Q8IW17|uniprotkb:Q96GY7|uniprotkb:Q9P0G1|uniprotkb:D3DU97|ensembl:ENSP00000301740 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:srrm2_human(display_long)|uniprotkb:Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa(gene name synonym)|uniprotkb:Splicing coactivator subunit SRm300(gene name synonym)|uniprotkb:300 kDa nuclear matrix antigen(gene name synonym)|uniprotkb:SRRM2(gene name)|psi-mi:SRRM2(display_short)|uniprotkb:KIAA0324(gene name synonym)|uniprotkb:SRL300(gene name synonym)|uniprotkb:SRM300(gene name synonym)|uniprotkb:HSPC075(orf name)|uniprotkb:Tax-responsive enhancer element-binding protein 803(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_057417.3|ensembl:ENSG00000167978(gene)|ensembl:ENST00000301740(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|mint:Q9UQ35|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|reactome:R-HSA-72163 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:3yyPAOaCzKSCEg5guJSbq0MWrHI9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q96B54 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-9995882|uniprotkb:O95054|uniprotkb:Q6X3Y3|ensembl:ENSP00000300811 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:zn428_human(display_long)|uniprotkb:C19orf37(gene name synonym)|uniprotkb:Enzyme-like protein PIT13(gene name synonym)|uniprotkb:ZNF428(gene name)|psi-mi:ZNF428(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_872304.2|ensembl:ENSG00000131116(gene)|ensembl:ENST00000300811(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038977 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:l2W8wXsSzmwgrqCkj4kE2r/WMYs9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P13489 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q8TF68 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-6115971|uniprotkb:O15407|uniprotkb:Q7Z722|uniprotkb:Q8N938|ensembl:ENSP00000354592|ensembl:ENSP00000380019 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:zn384_human(display_long)|uniprotkb:ZNF384(gene name)|psi-mi:ZNF384(display_short)|uniprotkb:CAGH1(gene name synonym)|uniprotkb:CIZ(gene name synonym)|uniprotkb:NMP4(gene name synonym)|uniprotkb:TNRC1(gene name synonym)|uniprotkb:CAG repeat protein 1(gene name synonym)|uniprotkb:CAS-interacting zinc finger protein(gene name synonym)|uniprotkb:Nuclear matrix transcription factor 4(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENST00000319770|ensembl:ENSP00000321650|ensembl:ENSP00000354592|ensembl:ENSP00000380019|ensembl:ENST00000355772|ensembl:ENSP00000348018|refseq:NP_001035009.1|refseq:NP_001129206.1|refseq:NP_597733.2|refseq:XP_016874430.1|refseq:XP_016874431.1|refseq:XP_016874432.1|refseq:XP_016874438.1|refseq:XP_016874439.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8TF68|ensembl:ENSG00000126746(gene)|ensembl:ENST00000361959(transcript)|ensembl:ENST00000396801(transcript) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:6TO45205H9niXg8StUmIooVLC289606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q8IZL8 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:iu03DsintVoo3gWzZX14SlHE0ao9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O15355 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-725702|ensembl:ENSP00000342778 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q08J23 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O00267 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P49711 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q96T23 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-926768|uniprotkb:Q86X86|uniprotkb:Q9H3L8|uniprotkb:Q9NVZ8|uniprotkb:Q9NYU0|intact:EBI-28986425|ensembl:ENSP00000311513 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rsf1_human(display_long)|uniprotkb:RSF1(gene name)|psi-mi:RSF1(display_short)|uniprotkb:HBXAP(gene name synonym)|uniprotkb:XAP8(gene name synonym)|uniprotkb:Hepatitis B virus X-associated protein(gene name synonym)|uniprotkb:HBV pX-associated protein 8(gene name synonym)|uniprotkb:p325 subunit of RSF chromatin-remodeling complex(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_057662.3|ensembl:ENSP00000311513|ensembl:ENST00000480887|ensembl:ENSP00000434509|ensembl:ENSG00000048649(gene)|ensembl:ENST00000308488(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031213"(RSF complex)|go:"GO:0042393"(histone binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR028938|interpro:IPR028942|reactome:R-HSA-606279 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:IoJZ6mEd2NHhbjnGJnPtWw+3dcE9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q8WXX5 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P61981 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P98160 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-947664|uniprotkb:Q16287|uniprotkb:Q9H3V5|uniprotkb:Q5SZI3|ensembl:ENSP00000363827 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:pgbm_human(display_long)|uniprotkb:Perlecan(gene name synonym)|uniprotkb:HSPG2(gene name)|psi-mi:HSPG2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001278789.1|refseq:NP_005520.4|ensembl:ENSG00000142798(gene)|ensembl:ENST00000374695(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0030154"(cell differentiation)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072359"(circulatory system development)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR000034(Laminin B)|interpro:IPR000082(SEA)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR023415|interpro:IPR036055|interpro:IPR036179|mint:P98160|rcsb pdb:3SH4|rcsb pdb:3SH5|reactome:R-HSA-1474228|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|reactome:R-HSA-977225 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:5ctWru2Fde+1Twjd9B7u24hsIKY9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q12948 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1175253|uniprotkb:Q86UP7|uniprotkb:Q9BYM1|uniprotkb:Q9NUE5|uniprotkb:Q9UDD0|uniprotkb:Q9UP06|ensembl:ENSP00000493906 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:foxc1_human(display_long)|uniprotkb:Forkhead-related protein FKHL7(gene name synonym)|uniprotkb:Forkhead-related transcription factor 3(gene name synonym)|uniprotkb:FOXC1(gene name)|psi-mi:FOXC1(display_short)|uniprotkb:FKHL7(gene name synonym)|uniprotkb:FREAC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENST00000645831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001654"(eye development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|ensembl:ENSG00000054598(gene)|go:"GO:0001822"(kidney development)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0021549"(cerebellum development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0008301"(DNA binding, bending)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:0060038"(cardiac muscle cell proliferation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR033067|go:"GO:0070098"(chemokine-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|mint:Q12948|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072010"(glomerular epithelium development)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902038"(positive regulation of hematopoietic stem cell differentiation)|go:"GO:1902257"(negative regulation of apoptotic process involved in outflow tract morphogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|ensembl:ENSP00000493906|refseq:NP_001444.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:+HuKwX8xMx86iCQW/a+vy/rWP389606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P51608 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P11047 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-714904|uniprotkb:Q5VYE7|ensembl:ENSP00000258341 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:lamc1_human(display_long)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:LAMC1(gene name)|psi-mi:LAMC1(display_short)|uniprotkb:LAMB2(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|mint:P11047|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9619665|go:"GO:0070062"(extracellular exosome)|refseq:NP_002284.3|ensembl:ENSG00000135862(gene)|ensembl:ENST00000258341(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007492"(endoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:2JMPODzaiqmTaLlmjdgvlv8e8+M9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UER7 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P18827 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2855248|uniprotkb:Q53QV0|uniprotkb:Q96HB7|uniprotkb:Q546D3|uniprotkb:D6W523|ensembl:ENSP00000254351|ensembl:ENSP00000370542 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:sdc1_human(display_long)|uniprotkb:SDC1(gene name)|psi-mi:SDC1(display_short)|uniprotkb:SDC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001006947.1|refseq:NP_002988.3|dip:DIP-1123N|ensembl:ENSG00000115884(gene)|ensembl:ENST00000254351(transcript)|ensembl:ENST00000381150(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0048627"(myoblast development)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055002"(striated muscle cell development)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031190|mint:P18827|rcsb pdb:4GVC|rcsb pdb:4GVD|rcsb pdb:6EJE|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3000170|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-449836|reactome:R-HSA-975634|go:"GO:0042476"(odontogenesis)|go:"GO:0042542"(response to hydrogen peroxide) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:SyiC0eBqj/X5xsWqRy9EWDxlmH09606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UBW7 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2797576|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904|refseq:XP_005266577.1|ensembl:ENSG00000121741(gene)|ensembl:ENST00000382871(transcript)|ensembl:ENST00000382874(transcript)|ensembl:ENST00000610343(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:XP_016876218.1|refseq:XP_011533526.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O43719 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:PttL+7D+505QAmcHRGNsc40haPY9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P49736 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UGN5 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2795348|uniprotkb:Q8TEU4|uniprotkb:Q9NUV2|uniprotkb:Q9UMR4|uniprotkb:Q9Y6C8|ensembl:ENSP00000250416 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:parp2_human(display_long)|uniprotkb:PARP2(gene name)|psi-mi:PARP2(display_short)|uniprotkb:ADPRT2(gene name synonym)|uniprotkb:ADPRTL2(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 2"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 2(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 2(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP2(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001036083.1|refseq:NP_005475.2|ensembl:ENSG00000129484(gene)|ensembl:ENST00000250416(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016570"(histone modification)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036616|go:"GO:0005634"(nucleus)|interpro:IPR036930|mint:Q9UGN5|rcsb pdb:3KCZ|rcsb pdb:3KJD|rcsb pdb:4PJV|rcsb pdb:4TVJ|rcsb pdb:4ZZX|rcsb pdb:4ZZY|rcsb pdb:5D5K|rcsb pdb:5DSY|rcsb pdb:6F1K|rcsb pdb:6F5B|rcsb pdb:6F5F|rcsb pdb:6TX3|rcsb pdb:6USJ|rcsb pdb:6X0L|rcsb pdb:6X0M|rcsb pdb:6X0N|rcsb pdb:7AEO|reactome:R-HSA-110362|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|dip:DIP-48934N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:0sLs7K5dQNmmhUwnGT9UIvparjU9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9NXF1 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2371062|uniprotkb:Q5T722|uniprotkb:Q5T723|uniprotkb:Q8NCN8|uniprotkb:Q8TDY0|uniprotkb:B4DYV2|ensembl:ENSP00000364037 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:tex10_human(display_long)|uniprotkb:TEX10(gene name)|psi-mi:TEX10(display_short)|uniprotkb:L18(orf name)|uniprotkb:Nbla10363(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_060216.2|refseq:NP_001155056.1|ensembl:ENSG00000136891(gene)|ensembl:ENST00000374902(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0071339"(MLL1 complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024679|interpro:IPR037947|mint:Q9NXF1|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:cQcRo1eExRkr/an7wvBN8Ttyatc9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P31939 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1048599|uniprotkb:Q13856|uniprotkb:Q53S28|uniprotkb:A8K202|uniprotkb:E9PBU3|ensembl:ENSP00000236959 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:pur9_human(display_long)|uniprotkb:ATIC(gene name)|psi-mi:ATIC(display_short)|uniprotkb:PURH(gene name synonym)|uniprotkb:OK/SW-cl.86(orf name)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_004035.2|ensembl:ENSG00000138363(gene)|ensembl:ENST00000236959(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|rcsb pdb:1P4R|rcsb pdb:1PKX|rcsb pdb:1PL0|rcsb pdb:5UY8|rcsb pdb:5UZ0|reactome:R-HSA-73817 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:Xe3388w/LOBYgag9P8Gp3IGo9wU9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q01081 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-632461|intact:EBI-14082807|ensembl:ENSP00000291552|intact:EBI-1053464|uniprotkb:Q701P4|uniprotkb:Q71RF1 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:u2af1_human(display_long)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)|uniprotkb:U2AF1(gene name)|psi-mi:U2AF1(display_short)|uniprotkb:U2AF35(gene name synonym)|uniprotkb:U2AFBP(gene name synonym)|uniprotkb:U2 small nuclear RNA auxiliary factor 1(gene name synonym)|uniprotkb:FP793(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001307575.1|refseq:NP_006749.1|refseq:NP_001307577.1|ensembl:ENSG00000160201(gene)|ensembl:ENST00000291552(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR009145(U2 auxiliary factor small subunit)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q01081|rcsb pdb:1JMT|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_001307580.1|refseq:NP_001020374.1|refseq:NP_001020375.1|dip:DIP-1108N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:n7tE+B4qBNnI/hiwspeQKrviXv89606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q6NT76 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2549423|ensembl:ENSP00000287701|ensembl:ENSP00000380516|uniprotkb:A8K3R8|uniprotkb:Q3Y6P1|uniprotkb:Q96GS5|uniprotkb:Q9H701|uniprotkb:A4K385|uniprotkb:B4DHY5|uniprotkb:D3DSU0 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:hmbx1_human(display_long)|uniprotkb:HMBOX1(gene name)|psi-mi:HMBOX1(display_short)|uniprotkb:HOT1(gene name synonym)|uniprotkb:Homeobox telomere-binding protein 1(gene name synonym)|uniprotkb:TAH1(gene name synonym)|uniprotkb:Telomere-associated homeobox-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000147421(gene)|ensembl:ENST00000287701(transcript)|ensembl:ENST00000397358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR006899(Hepatocyte nuclear factor 1, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR040363|mint:Q6NT76|rcsb pdb:2CUF|rcsb pdb:4J19|interpro:IPR001387(Helix-turn-helix type 3)|refseq:NP_001129198.1|refseq:NP_078843.2|refseq:NP_001311312.1|refseq:NP_001311313.1|refseq:NP_001311314.1|refseq:NP_001311315.1|refseq:NP_001311316.1|refseq:NP_001311317.1|refseq:NP_001311318.1|refseq:NP_001311319.1|refseq:NP_001311320.1|refseq:NP_001311321.1|refseq:NP_001311322.1|refseq:NP_001311323.1|refseq:NP_001311324.1|refseq:NP_001311311.1|refseq:NP_001317427.1|refseq:XP_016869314.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:Vap52i4o7ETkoZDzQ7zQqCHXVCA9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P42166 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q7Z6I8 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-9995695|uniprotkb:D3DQA7|uniprotkb:Q86Y53|uniprotkb:Q8N1T9|ensembl:ENSP00000337044|ensembl:ENSP00000378427|ensembl:ENSP00000395764 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ce024_human(display_long)|uniprotkb:C5orf24(gene name)|psi-mi:C5orf24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001129058.1|refseq:NP_001287823.1|refseq:NP_689622.2|refseq:XP_005271946.1|refseq:XP_016864538.1|refseq:XP_016864539.1|ensembl:ENSG00000181904(gene)|ensembl:ENST00000338051(transcript)|ensembl:ENST00000394976(transcript)|ensembl:ENST00000435259(transcript)|interpro:IPR040419 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:Ye+nbD86YyjmFkryW2orfM3Wh4w9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q14151 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-352869|ensembl:ENSP00000252542|uniprotkb:Q8TB13|uniprotkb:B4DKG3|intact:EBI-2948582 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:safb2_human(display_long)|uniprotkb:SAFB2(gene name)|psi-mi:SAFB2(display_short)|uniprotkb:KIAA0138(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000130254(gene)|ensembl:ENST00000252542(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|interpro:IPR035979|go:"GO:0042802"(identical protein binding)|interpro:IPR036361|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|mint:Q14151|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034782|refseq:NP_055464.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:4/eQxEPzUXIuUuqP2ogEL+zY31g9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P05549 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-347351|uniprotkb:Q13777|uniprotkb:Q5TAV5|uniprotkb:Q8N1C6 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ap2a_human(display_long)|uniprotkb:TFAP2(gene name synonym)|uniprotkb:TFAP2A(gene name)|psi-mi:TFAP2A(display_short)|uniprotkb:AP2TF(gene name synonym)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001035890.1|refseq:NP_003211.1|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|interpro:IPR013854(Transcription factor AP-2, C-terminal)|refseq:NP_001027451.1|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-HSA-3232118|reactome:R-HSA-8864260|reactome:R-HSA-8866904|reactome:R-HSA-8866906|reactome:R-HSA-8866907|reactome:R-HSA-8866910|reactome:R-HSA-8866911|reactome:R-HSA-8869496|mint:P05549 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:58UfJTF18ePGZ/QCtxCTFE4tmn89606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P28370 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P20226 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q96RR1 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-716458|uniprotkb:Q6MZX2|uniprotkb:Q96RR0|uniprotkb:Q6PJP5|uniprotkb:B2CQL2|ensembl:ENSP00000309595 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:peo1_human(display_long)|uniprotkb:TWNK(gene name)|psi-mi:TWNK(display_short)|uniprotkb:C10orf2(gene name synonym)|uniprotkb:PEO1(gene name synonym)|uniprotkb:Progressive external ophthalmoplegia 1 protein(gene name synonym)|uniprotkb:T7 gp4-like protein with intramitochondrial nucleoid localization(gene name synonym)|uniprotkb:T7-like mitochondrial DNA helicase(gene name synonym)|uniprotkb:Twinkle protein, mitochondrial(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001157284.1|refseq:NP_068602.2|ensembl:ENST00000311916(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|ensembl:ENSG00000107815(gene)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR027417|interpro:IPR034154|mint:Q96RR1|reactome:R-HSA-2151201 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:asX2NETd8o4GZrWe8gIUntbtUpA9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P22670 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-716037|ensembl:ENSP00000254325|ensembl:ENSP00000500760 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rfx1_human(display_long)|uniprotkb:Transcription factor RFX1(gene name synonym)|uniprotkb:Regulatory factor X 1(gene name synonym)|uniprotkb:Enhancer factor C(gene name synonym)|uniprotkb:RFX1(gene name)|psi-mi:RFX1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_002909.4|ensembl:ENSG00000288283(gene)|ensembl:ENST00000254325(transcript)|ensembl:ENST00000672295(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000132005(gene)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|mint:P22670|rcsb pdb:1DP7|go:"GO:1990837"(sequence-specific double-stranded DNA binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:wuth5iU8m39Wo6gmcElDKuF2pLs9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P46821 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O76021 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P00558 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O00468 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-947482|uniprotkb:Q5SVA2|uniprotkb:Q60FE1|uniprotkb:Q7KYS8|uniprotkb:Q8N4J5|uniprotkb:Q96IC1|uniprotkb:Q9BTD4|uniprotkb:Q5SVA1 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:agrin_human(display_long)|uniprotkb:AGRN(gene name)|psi-mi:AGRN(display_short)|uniprotkb:AGRIN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_940978.2|interpro:IPR004850(Agrin NtA)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR000082(SEA)|interpro:IPR008993(TIMP-like, OB-fold)|refseq:XP_005244806.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003884(Factor I membrane attack complex)|mint:O00468|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043236"(laminin binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050808"(synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-419037|reactome:R-HSA-4420332|reactome:R-HSA-975634|interpro:IPR036058|interpro:IPR036364|refseq:NP_001292204.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:LRk4v4aYLk5kep9EIbjjiCGM7OM9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q00059 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P39060 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-981314|uniprotkb:Q58EX6|uniprotkb:Q6RZ39|uniprotkb:Q6RZ40|uniprotkb:Q6RZ41|uniprotkb:Q8N4S4|uniprotkb:Q8WXI5|uniprotkb:Q96T70|uniprotkb:Q9UK38|uniprotkb:Q9Y6Q7|uniprotkb:A8MVI4|ensembl:ENSP00000352798|uniprotkb:Q9Y6Q8 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:coia1_human(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_085059.2|refseq:NP_569712.2|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR020067|interpro:IPR035523|interpro:IPR036790|rcsb pdb:1BNL|rcsb pdb:3HON|rcsb pdb:3HSH|reactome:R-HSA-1442490|reactome:R-HSA-1592389|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-8948216|ensembl:ENSG00000182871(gene)|ensembl:ENST00000359759(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR010363(Protein of unknown function DUF959, collagen XVIII, N-terminal)|interpro:IPR010515(Collagenase NC10 and endostatin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_569711.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:wLRIpnIxV06w/L+TD0ZldrjEsVs9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P62805 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q15424 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-348298|ensembl:ENSP00000292123|uniprotkb:O60406|uniprotkb:B7Z5B6|uniprotkb:F5H0H3|uniprotkb:Q59HH8|uniprotkb:A0AV56|uniprotkb:B7ZLP6 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:safb1_human(display_long)|uniprotkb:SAFB(gene name)|psi-mi:SAFB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HET(gene name synonym)|uniprotkb:SAFB1(gene name synonym)|uniprotkb:HSP27 estrogen response element-TATA box-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030496"(midbody)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000160633(gene)|interpro:IPR034781|interpro:IPR035979|ensembl:ENST00000292123(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|interpro:IPR036361|mint:Q15424|reactome:R-HSA-3899300|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|refseq:NP_002958.2|refseq:NP_001307500.1|refseq:NP_001307501.1|refseq:NP_001188269.1|refseq:NP_001188267.1|refseq:NP_001188268.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:Y31we6crSBL4G6uviNAfXyX0xfM9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q8IWI9 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q16531 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q99615 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-357552|ensembl:ENSP00000406463|uniprotkb:Q7Z784 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:dnjc7_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)|uniprotkb:TPR2(gene name synonym)|uniprotkb:TTC2(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000168259(gene)|ensembl:ENST00000457167(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036869|reactome:R-HSA-3371453|refseq:NP_003306.3|refseq:XP_011523469.1|refseq:XP_011523470.1|refseq:XP_011523471.1|refseq:NP_001138238.1|refseq:XP_016880483.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:eZ1/nlVA9bOU/N3yrJ3pWrnM1P09606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q92766 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1210379|uniprotkb:E2GM80|uniprotkb:E2GM81|uniprotkb:A2RRF5|uniprotkb:O75567|uniprotkb:O75568|uniprotkb:Q5VYB2|uniprotkb:Q6BEP5|uniprotkb:Q6BEP6|uniprotkb:Q6BEP8|uniprotkb:Q86SU2|uniprotkb:Q9Y474|ensembl:ENSP00000305560|ensembl:ENSP00000369265 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rreb1_human(display_long)|uniprotkb:RREB1(gene name)|psi-mi:RREB1(display_short)|uniprotkb:FINB(gene name synonym)|uniprotkb:Raf-responsive zinc finger protein LZ321(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 1(gene name synonym)|uniprotkb:Finger protein in nuclear bodies(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:XP_011513097.1|refseq:NP_001003698.1|refseq:NP_001003699.1|refseq:NP_001003700.1|refseq:NP_001161816.1|refseq:XP_006715220.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|ensembl:ENSG00000124782(gene)|ensembl:ENST00000349384(transcript)|ensembl:ENST00000379933(transcript) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:BKnzSXiZmB0IL9opvk8w6WiDMU49606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P07942 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-949174|ensembl:ENSP00000222399|uniprotkb:Q14D91 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:lamb1_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000091136(gene)|ensembl:ENST00000222399(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042476"(odontogenesis)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P07942|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|go:"GO:0043259"(laminin-10 complex)|reactome:R-HSA-9619665|refseq:NP_002282.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:ZAg5y5cSIvyhPYPhe9BAHMnE1rs9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q14257 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q6ZU65 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-9661773|uniprotkb:A4D1S2|uniprotkb:Q2YDY4|uniprotkb:Q6P1K0|uniprotkb:Q86XN9|uniprotkb:Q8N7D1|ensembl:ENSP00000418648 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ubn2_human(display_long)|uniprotkb:UBN2(gene name)|psi-mi:UBN2(display_short)|uniprotkb:KIAA2030(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSP00000418648|refseq:NP_775840.3|dip:DIP-47312N|ensembl:ENSG00000157741(gene)|ensembl:ENST00000473989(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026943|interpro:IPR026947|mint:Q6ZU65 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:Z45kNtHT1rLdgqkCTrcRGD7L2749606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P46013 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-876367|uniprotkb:Q5VWH2|ensembl:ENSP00000357643 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ki67_human(display_long)|uniprotkb:MKI67(gene name)|psi-mi:MKI67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001139438.1|refseq:NP_002408.3|dip:DIP-28132N|ensembl:ENSG00000148773(gene)|ensembl:ENST00000368654(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012568(K167R)|interpro:IPR029334|mint:P46013|rcsb pdb:1R21|rcsb pdb:2AFF|rcsb pdb:5J28 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:kyrLLOv4HSqah1Y6HtzebG978Kw9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9P0M6 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-3922608|uniprotkb:Q5SQT2|ensembl:ENSP00000503835|ensembl:ENSP00000362352 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:h2aw_human(display_long)|uniprotkb:MACROH2A2(gene name)|psi-mi:MACROH2A2(display_short)|uniprotkb:H2AFY2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 dip:DIP-48563N|refseq:NP_061119.1|ensembl:ENSG00000099284(gene)|ensembl:ENST00000373255(transcript)|ensembl:ENST00000679349(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007420"(brain development)|go:"GO:0007549"(dosage compensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR002119(Histone H2A)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|interpro:IPR032454|interpro:IPR035796|interpro:IPR043472|rcsb pdb:2XD7|rcsb pdb:6FY5 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:xOLJc5I2oZLPBDLrA5IT2lYBQFM9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q92522 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UGU0 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P21281 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-4290814|uniprotkb:Q14544|uniprotkb:Q15859|uniprotkb:B2R5Z3|uniprotkb:D3DSQ5|uniprotkb:Q96IR0|ensembl:ENSP00000276390 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:vatb2_human(display_long)|uniprotkb:ATP6V1B2(gene name)|psi-mi:ATP6V1B2(display_short)|uniprotkb:ATP6B2(gene name synonym)|uniprotkb:VPP3(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:HO57(gene name synonym)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001684.2|ensembl:ENSG00000147416(gene)|ensembl:ENST00000276390(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P21281|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|dip:DIP-47433N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:CikZS+29TqYLiADRWgVESqCpg689606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P09874 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O94880 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2680164|uniprotkb:B4DI82|uniprotkb:A7MCZ3|ensembl:ENSP00000385795 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:phf14_human(display_long)|uniprotkb:KIAA0783(gene name synonym)|uniprotkb:PHF14(gene name)|psi-mi:PHF14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_055475.2|ensembl:ENSG00000106443(gene)|ensembl:ENST00000403050(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:O94880 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:5x6w7H9UP9mf4xk3lXYfAHaIo2Q9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P09936 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9NRL2 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-927511|uniprotkb:Q9NZ15|uniprotkb:Q9P065|uniprotkb:Q9UIG1|uniprotkb:Q9Y3V3|ensembl:ENSP00000353458|ensembl:ENSP00000371859 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:baz1a_human(display_long)|uniprotkb:BAZ1A(gene name)|psi-mi:BAZ1A(display_short)|uniprotkb:ACF1(gene name synonym)|uniprotkb:WCRF180(gene name synonym)|uniprotkb:HSPC317(orf name)|uniprotkb:ATP-utilizing chromatin assembly and remodeling factor 1(gene name synonym)|uniprotkb:ATP-dependent chromatin-remodeling protein(gene name synonym)|uniprotkb:Williams syndrome transcription factor-related chromatin-remodeling factor 180(gene name synonym)|uniprotkb:CHRAC subunit ACF1(gene name synonym)|uniprotkb:hWALp1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_038476.2|refseq:NP_872589.1|dip:DIP-36071N|ensembl:ENSG00000198604(gene)|ensembl:ENST00000360310(transcript)|ensembl:ENST00000382422(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008623"(CHRAC)|go:"GO:0016573"(histone acetylation)|go:"GO:0016590"(ACF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037325|rcsb pdb:5UIY - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:1N6/uH2kUWs1/HdPhSI2a/UnbqI9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9Y5B9 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1046849|uniprotkb:Q6GMT8|uniprotkb:Q6P2F1|uniprotkb:Q6PJM1|uniprotkb:Q9NRX0|ensembl:ENSP00000216297 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:sp16h_human(display_long)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:SUPT16H(gene name)|psi-mi:SUPT16H(display_short)|uniprotkb:FACT140(gene name synonym)|uniprotkb:FACTP140(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000092201(gene)|ensembl:ENST00000216297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|mint:Q9Y5B9|rcsb pdb:4Z2M|rcsb pdb:4Z2N|rcsb pdb:5E5B|rcsb pdb:5UMT|rcsb pdb:5UMU|rcsb pdb:5XM2|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|refseq:NP_009123.1|dip:DIP-42757N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:jLK5dOF3mEyI0UbZhcNgtdlG+WI9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9BZE4 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1056249|uniprotkb:O95446|uniprotkb:Q9NVJ8|uniprotkb:B3KMC5|uniprotkb:B4DY13|uniprotkb:B7Z7A3|uniprotkb:Q5T3R8|ensembl:ENSP00000354040 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:gtpb4_human(display_long)|uniprotkb:GTPBP4(gene name)|psi-mi:GTPBP4(display_short)|uniprotkb:CRFG(gene name synonym)|uniprotkb:NOG1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_036473.2|ensembl:ENSG00000107937(gene)|ensembl:ENST00000360803(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q9BZE4|rcsb pdb:6LSS|rcsb pdb:6LU8 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:wTcBrIj6c27um4RnJH81grRgutc9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O60264 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q14839 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P53621 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P46100 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-396461|ensembl:ENSP00000362441|ensembl:ENSP00000378967|uniprotkb:P51068|uniprotkb:Q15886|uniprotkb:Q59FB5|uniprotkb:Q59H31|uniprotkb:Q5H9A2|uniprotkb:Q5JWI4|uniprotkb:Q7Z2J1|uniprotkb:Q9H0Z1|uniprotkb:Q9NTS3|uniprotkb:D3DTE2 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:atrx_human(display_long)|uniprotkb:ATRX(gene name)|psi-mi:ATRX(display_short)|uniprotkb:RAD54L(gene name synonym)|uniprotkb:XH2(gene name synonym)|uniprotkb:ATP-dependent helicase ATRX(gene name synonym)|uniprotkb:X-linked helicase II(gene name synonym)|uniprotkb:X-linked nuclear protein(gene name synonym)|uniprotkb:Znf-HX(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000085224(gene)|go:"GO:0015616"(DNA translocase activity)|ensembl:ENST00000373344(transcript)|ensembl:ENST00000395603(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0006306"(DNA methylation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016604"(nuclear body)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016605"(PML body)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030900"(forebrain development)|go:"GO:0031297"(replication fork processing)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035128"(post-embryonic forelimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070615"|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900112"(regulation of histone H3-K9 trimethylation)|go:"GO:1901581"(negative regulation of telomeric RNA transcription from RNA pol II promoter)|go:"GO:1901582"(positive regulation of telomeric RNA transcription from RNA pol II promoter)|go:"GO:1904908"(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025766|interpro:IPR027417|interpro:IPR038718|interpro:IPR041430|mint:P46100|rcsb pdb:2JM1|rcsb pdb:2LBM|rcsb pdb:2LD1|rcsb pdb:3QL9|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:3QLN|rcsb pdb:4W5A|rcsb pdb:5GRQ|rcsb pdb:5Y18|rcsb pdb:5Y6O|rcsb pdb:6G0O|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_000480.3|refseq:NP_612114.2|dip:DIP-31532N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:3t+VQYWuUjQQSuDSQ0Urst2hha09606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q5VZL5 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2514659|intact:EBI-28984130|ensembl:ENSP00000322915|uniprotkb:A0JP19|uniprotkb:O43308|uniprotkb:A0JP20|uniprotkb:Q5T5E2|uniprotkb:Q7L3Q4|uniprotkb:Q5T5E1|intact:EBI-2556245 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:zmym4_human(display_long)|uniprotkb:ZMYM4(gene name)|psi-mi:ZMYM4(display_short)|uniprotkb:KIAA0425(gene name synonym)|uniprotkb:ZNF262(gene name synonym)|uniprotkb:Zinc finger protein 262(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000146463(gene)|ensembl:ENST00000314607(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|refseq:XP_016858292.1|refseq:XP_016858293.1|refseq:XP_011540725.1|refseq:XP_011540727.1|refseq:NP_005086.2|ensembl:ENSP00000322915|refseq:XP_005271388.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:jc8YwR+37J3uD08cXiUnOA2hHEI9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9Y6J0 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2795712|uniprotkb:Q9Y460|uniprotkb:G5E9F3|uniprotkb:Q6PHY0|intact:EBI-28988204|ensembl:ENSP00000263119|ensembl:ENSP00000381364 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:cabin_human(display_long)|uniprotkb:CABIN1(gene name)|psi-mi:CABIN1(display_short)|uniprotkb:KIAA0330(gene name synonym)|uniprotkb:Calcineurin inhibitor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001186210.1|refseq:NP_001188358.1|refseq:NP_036427.1|refseq:XP_016884172.1|ensembl:ENSP00000263119|ensembl:ENSP00000381364|ensembl:ENST00000405822|ensembl:ENSP00000384694|ensembl:ENSG00000099991(gene)|ensembl:ENST00000263119(transcript)|ensembl:ENST00000398319(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016235"(aggresome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015134(MEF2 binding)|interpro:IPR019734|interpro:IPR033053|mint:Q9Y6J0|rcsb pdb:1N6J|reactome:R-HSA-2559584 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:b4BLYv/aw7zl2SZQXLXAQr+RmY49606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q8N163 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:O15015 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-745608|uniprotkb:Q8IVD8|ensembl:ENSP00000300850 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:zn646_human(display_long)|uniprotkb:KIAA0296(gene name synonym)|uniprotkb:ZNF646(gene name)|psi-mi:ZNF646(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_055514.3|refseq:XP_011544292.1|ensembl:ENSG00000167395(gene)|ensembl:ENST00000300850(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_005255767.1|refseq:XP_005255768.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:LLCOZY29R+2cHozH65lymJNIjRU9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q01826 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-743747|uniprotkb:C9JTR6|uniprotkb:B3KXF1|uniprotkb:Q59EQ0|intact:EBI-28974629|ensembl:ENSP00000341024|ensembl:ENSP00000399708 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:satb1_human(display_long)|uniprotkb:Special AT-rich sequence-binding protein 1(gene name synonym)|uniprotkb:SATB1(gene name)|psi-mi:SATB1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSP00000341024|ensembl:ENST00000417717|ensembl:ENSP00000399518|ensembl:ENSP00000399708|refseq:NP_001124482.1|refseq:NP_001182399.1|refseq:NP_002962.1|refseq:NP_001309801.1|refseq:NP_001309802.1|refseq:NP_001309803.1|refseq:NP_001309804.1|refseq:NP_001309800.1|refseq:XP_011532290.1|refseq:XP_011532291.1|dip:DIP-48757N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q01826|rcsb pdb:1YSE|rcsb pdb:2L1P|rcsb pdb:2MW8|rcsb pdb:2O49|rcsb pdb:2O4A|rcsb pdb:3NZL|rcsb pdb:3TUO|rcsb pdb:6LFF|reactome:R-HSA-111465|reactome:R-HSA-4551638|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSG00000182568(gene)|ensembl:ENST00000338745(transcript)|ensembl:ENST00000454909(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:xR1uXIoTJqiU6vzeM9h8AccM8fc9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UIS9 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-867196|uniprotkb:K7ELI2|uniprotkb:Q9UNZ9|uniprotkb:K7EQZ4|uniprotkb:K7ESN0|uniprotkb:A4UTZ0|uniprotkb:O15248|uniprotkb:O95241|uniprotkb:Q7Z7B5|uniprotkb:Q8N4W4|uniprotkb:Q9UNZ6|uniprotkb:Q9UNZ7|uniprotkb:Q9UNZ8|uniprotkb:B4DXJ5|uniprotkb:E9PEC5|intact:EBI-10977266|ensembl:ENSP00000269468|ensembl:ENSP00000372407|ensembl:ENSP00000467017 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:mbd1_human(display_long)|uniprotkb:CXXC3(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD1(gene name synonym)|uniprotkb:Protein containing methyl-CpG-binding domain 1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 3(gene name synonym)|uniprotkb:MBD1(gene name)|psi-mi:MBD1(display_short)|uniprotkb:PCM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001191065.1|refseq:NP_001191068.1|refseq:NP_001191071.1|refseq:NP_001191072.1|refseq:NP_001191080.1|refseq:NP_002375.1|refseq:NP_056669.2|refseq:NP_056670.2|refseq:NP_056671.2|refseq:NP_056723.2|refseq:XP_011524295.1|refseq:XP_016881249.1|refseq:XP_016881259.1|refseq:XP_016881260.1|refseq:XP_016881265.1|refseq:XP_011524296.1|refseq:XP_011524308.1|refseq:NP_001191066.1|refseq:NP_001191067.1|refseq:NP_001191069.1|refseq:NP_001191070.1|refseq:XP_005258328.1|ensembl:ENSG00000141644(gene)|ensembl:ENST00000269468(transcript)|ensembl:ENST00000382948(transcript)|ensembl:ENST00000591416(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR016177(DNA-binding, integrase-type)|mint:Q9UIS9|rcsb pdb:1D9N|rcsb pdb:1IG4|rcsb pdb:4D4W|rcsb pdb:5W9Q|rcsb pdb:6D1T|reactome:R-HSA-3899300 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:I6StIYNuO8jT6ZR1YxoZnzDrP/I9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q04917 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UIF9 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q07021 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P13010 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UIG0 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-927482|uniprotkb:O95039|uniprotkb:O95247|uniprotkb:O95277|uniprotkb:B9EGK3|uniprotkb:Q6P1K4|uniprotkb:Q86UJ6|uniprotkb:D3DXE9|ensembl:ENSP00000342434|ensembl:ENSP00000385442 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:baz1b_human(display_long)|uniprotkb:BAZ1B(gene name)|psi-mi:BAZ1B(display_short)|uniprotkb:WBSC10(gene name synonym)|uniprotkb:WBSCR9(gene name synonym)|uniprotkb:WSTF(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 9 protein(gene name synonym)|uniprotkb:Williams syndrome transcription factor(gene name synonym)|uniprotkb:WBSCR10(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 10 protein(gene name synonym)|uniprotkb:Bromodomain adjacent to zinc finger domain protein 1B(gene name synonym)|uniprotkb:hWALp2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_115784.1|refseq:XP_016868262.1|dip:DIP-35642N|ensembl:ENSG00000009954(gene)|ensembl:ENST00000339594(transcript)|ensembl:ENST00000404251(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0035173"(histone kinase activity)|go:"GO:0042393"(histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037375|mint:Q9UIG0|rcsb pdb:1F62|rcsb pdb:5NNF|reactome:R-HSA-5250924|reactome:R-HSA-5693565 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:1GTflhs9UUxTv4SPOYPKmuKAtSQ9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P29590 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P49116 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UNY4 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2322921|uniprotkb:A8K4Q2|uniprotkb:O75921|uniprotkb:Q5T2K7|uniprotkb:Q5VVU8|uniprotkb:Q8N6I8|intact:EBI-28970288|ensembl:ENSP00000358478 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ttf2_human(display_long)|uniprotkb:TTF2(gene name)|psi-mi:TTF2(display_short)|uniprotkb:RNA polymerase II termination factor(gene name synonym)|uniprotkb:Transcription release factor 2(gene name synonym)|uniprotkb:Lodestar homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_003585.3|ensembl:ENSP00000358478|refseq:XP_016858044.1|ensembl:ENSG00000116830(gene)|ensembl:ENST00000369466(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|mint:Q9UNY4 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:r4tIdwX2iegp6TXTVoLRPZnhN1A9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q93009 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P45973 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P24468 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2795198|uniprotkb:B6ZGU1|uniprotkb:Q03754|uniprotkb:B4DQJ2|uniprotkb:Q3KQR7|ensembl:ENSP00000377721 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:cot2_human(display_long)|uniprotkb:NR2F2(gene name)|psi-mi:NR2F2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:TFCOUP2(gene name synonym)|uniprotkb:COUP transcription factor II(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group F member 2(gene name synonym)|uniprotkb:Apolipoprotein A-I regulatory protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_066285.1|refseq:NP_001138627.1|refseq:NP_001138628.1|refseq:NP_001138629.1|ensembl:ENSG00000185551(gene)|ensembl:ENST00000394166(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008585"(female gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0009956"(radial pattern formation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032355"(response to estradiol)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060173"(limb development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:3CJW|reactome:R-HSA-381340|dip:DIP-29713N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:XsZyqUr06sQQaD3oXAA3IEa6Dug9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9Y4W2 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9UQR1 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2688184|uniprotkb:Q58EY5|uniprotkb:O43591|uniprotkb:O00389|uniprotkb:D3DN27|ensembl:ENSP00000420448|ensembl:ENSP00000353863|ensembl:ENSP00000419322|ensembl:ENSP00000420335|uniprotkb:Q6PJ98 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:zn148_human(display_long)|uniprotkb:ZBP89(gene name synonym)|uniprotkb:Transcription factor ZBP-89(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 89(gene name synonym)|uniprotkb:ZNF148(gene name)|psi-mi:ZNF148(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_068799.2|ensembl:ENST00000360647(transcript)|ensembl:ENST00000484491(transcript)|ensembl:ENST00000485866(transcript)|ensembl:ENST00000492394(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006968"(cellular defense response)|go:"GO:0007276"(gamete generation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021762"(substantia nigra development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9UQR1|ensembl:ENSG00000163848(gene)|refseq:NP_001335353.1|refseq:NP_001335354.1|refseq:NP_001335355.1|refseq:NP_001335356.1|refseq:NP_001335357.1|refseq:NP_001335358.1|refseq:NP_001335359.1|refseq:NP_001335360.1|refseq:NP_001335361.1|refseq:NP_001335362.1|ensembl:ENSP00000353863|ensembl:ENSP00000420335|ensembl:ENSP00000420448|ensembl:ENSP00000419322 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:2H8lAaonZqAnCWDtUN8q55+03h49606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q7Z5J4 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-743815|uniprotkb:Q8N3B4|uniprotkb:Q8ND08|uniprotkb:Q8WU64|uniprotkb:Q96JK5|uniprotkb:Q9H1C1|uniprotkb:Q9H1C2|uniprotkb:Q9UF69|ensembl:ENSP00000323074 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:rai1_human(display_long)|uniprotkb:RAI1(gene name)|psi-mi:RAI1(display_short)|uniprotkb:KIAA1820(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_109590.3|ensembl:ENSG00000108557(gene)|ensembl:ENST00000353383(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|reactome:R-HSA-400253|reactome:R-HSA-9707616 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:6+FvWXfA5BZ9tPSFKXyamhKmGFY9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q8WWQ0 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-722984|uniprotkb:A7J992|ensembl:ENSP00000275034|uniprotkb:Q05CQ9|uniprotkb:Q5VVH4|uniprotkb:Q66I29|uniprotkb:Q69YV1|uniprotkb:Q8NBZ5|uniprotkb:Q96H52|uniprotkb:Q96ME2|uniprotkb:Q9H261|uniprotkb:B2RPK4 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:phip_human(display_long)|uniprotkb:IRS-1 PH domain-binding protein(gene name synonym)|uniprotkb:WD repeat-containing protein 11(gene name synonym)|uniprotkb:PHIP(gene name)|psi-mi:PHIP(display_short)|uniprotkb:WDR11(gene name synonym)|uniprotkb:DDB1- and CUL4-associated factor 14(gene name synonym)|uniprotkb:DCAF14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000146247(gene)|ensembl:ENST00000275034(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005158"(insulin receptor binding)|rcsb pdb:5ENC|rcsb pdb:5ENE|rcsb pdb:5ENF|rcsb pdb:5ENH|rcsb pdb:5ENI|rcsb pdb:5ENJ|rcsb pdb:5RJI|rcsb pdb:5RJJ|rcsb pdb:5RJK|rcsb pdb:5RJL|rcsb pdb:5RJM|rcsb pdb:5RJN|rcsb pdb:5RJO|rcsb pdb:5RJP|rcsb pdb:5RJQ|rcsb pdb:5RJR|rcsb pdb:5RJX|rcsb pdb:5RJY|rcsb pdb:5RJZ|rcsb pdb:5RK0|rcsb pdb:5RJS|rcsb pdb:5RJT|rcsb pdb:5RJU|rcsb pdb:5RJV|rcsb pdb:5RJW|rcsb pdb:5RK1|rcsb pdb:5RK2|rcsb pdb:5RK3|rcsb pdb:5RK4|rcsb pdb:5RK5|rcsb pdb:5RK6|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001487(Bromodomain)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018359|interpro:IPR019775|interpro:IPR028738|interpro:IPR036322|interpro:IPR036427|rcsb pdb:3MB3|rcsb pdb:5ENB|rcsb pdb:5RK7|rcsb pdb:5RK8|rcsb pdb:5RK9|rcsb pdb:5RKA|rcsb pdb:5RKB|rcsb pdb:5RKC|rcsb pdb:5RKD|rcsb pdb:5RKE|rcsb pdb:5RKF|rcsb pdb:5RKG|rcsb pdb:5RKH|rcsb pdb:5RKI|rcsb pdb:5RKJ|rcsb pdb:5RKK|rcsb pdb:5RKL|rcsb pdb:5RKM|rcsb pdb:5RKN|rcsb pdb:5RKO|rcsb pdb:5RKP|rcsb pdb:5RKQ|rcsb pdb:5RKR|rcsb pdb:5RKS|rcsb pdb:5RKT|rcsb pdb:5RKU|rcsb pdb:5RKV|rcsb pdb:5RKW|rcsb pdb:5RKX|rcsb pdb:5RKY|rcsb pdb:5S8C|rcsb pdb:5S8D|rcsb pdb:5S8E|rcsb pdb:5S8F|rcsb pdb:5S8G|rcsb pdb:5S8H|rcsb pdb:5S8I|rcsb pdb:5S8J|rcsb pdb:5S8K|rcsb pdb:5S8L|rcsb pdb:5S8M|rcsb pdb:5S8N|rcsb pdb:5S8O|rcsb pdb:5S8P|rcsb pdb:5S8Q|rcsb pdb:5S8R|rcsb pdb:5S8S|rcsb pdb:5S8T|rcsb pdb:5S8U|rcsb pdb:5S8V|rcsb pdb:5S8W|rcsb pdb:5S8X|rcsb pdb:5S8Y|rcsb pdb:5S8Z|rcsb pdb:5S90|rcsb pdb:5S91|rcsb pdb:5S92|rcsb pdb:5S93|rcsb pdb:5S94|rcsb pdb:5S95|rcsb pdb:5S96|rcsb pdb:5S97|rcsb pdb:5S98|rcsb pdb:5S99|rcsb pdb:5S9A|rcsb pdb:5S9B|rcsb pdb:5S9C|rcsb pdb:5S9D|rcsb pdb:5S9E|rcsb pdb:5S9F|rcsb pdb:5S9G|rcsb pdb:5S9H|rcsb pdb:5S9I|rcsb pdb:5S9J|rcsb pdb:7AV8|rcsb pdb:7AV9|rcsb pdb:7BBO|rcsb pdb:7BBP|reactome:R-HSA-9013418|refseq:NP_060404.4 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:TptYI8D8CdPa97zbqW3sjmFti289606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:Q9H4L4 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-2880236|ensembl:ENSP00000314029|ensembl:ENSP00000403712|uniprotkb:Q96PS4|uniprotkb:Q66K15|uniprotkb:Q86VS7|uniprotkb:Q9Y3W9 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:senp3_human(display_long)|uniprotkb:SENP3(gene name)|psi-mi:SENP3(display_short)|uniprotkb:SSP3(gene name synonym)|uniprotkb:SUSP3(gene name synonym)|uniprotkb:SUMO-1-specific protease 3(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 ensembl:ENSG00000161956(gene)|ensembl:ENST00000321337(transcript)|ensembl:ENST00000429205(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR037945|interpro:IPR038765|mint:Q9H4L4|reactome:R-HSA-6791226|refseq:NP_056485.2|dip:DIP-47511N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:sE4k87ORoxSjBkbccPsXLYzuqII9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 uniprotkb:P34741 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 intact:EBI-1172957|uniprotkb:Q9H6V1|uniprotkb:B3KQA3|ensembl:ENSP00000307046|uniprotkb:Q6PIS6 psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:sdc2_human(display_long)|uniprotkb:SDC2(gene name)|psi-mi:SDC2(display_short)|uniprotkb:HSPG1(gene name synonym)|uniprotkb:Fibroglycan(gene name synonym)|uniprotkb:Heparan sulfate proteoglycan core protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9995881|imex:IM-23523-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 refseq:NP_002989.2|reactome:R-HSA-975634|reactome:R-HSA-8957275|ensembl:ENSG00000169439(gene)|ensembl:ENST00000302190(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031201|mint:P34741|rcsb pdb:6ITH|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3000170|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-381426|reactome:R-HSA-3928662|reactome:R-HSA-4420332|dip:DIP-29943N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/07/08 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 rogid:dUYGfiWzMHbYLZdV/ibV6RmeYUA9606 intact-crc:8174FBD7A1FE0C7C|rigid:z7wVjrA8W//zESnW3HxWee4d3Tk false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P16104 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BSC4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-7001376|uniprotkb:Q53RC9|uniprotkb:Q9H855|uniprotkb:Q96TA5|uniprotkb:Q9H7Y7|uniprotkb:A8K3R5|intact:MINT-3060916|uniprotkb:B4DLV0|ensembl:ENSP00000371101 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nol10_human(display_long)|uniprotkb:NOL10(gene name)|psi-mi:NOL10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_079170.2|refseq:NP_001248323.1|refseq:NP_001248321.1|ensembl:ENSG00000115761(gene)|ensembl:ENST00000381685(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012580(NUC153)|interpro:IPR036322|interpro:IPR040382|mint:Q9BSC4 - - comment:mint figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:PiblslntTRSvRQnk82fSgtVJbXE9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y3A4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-7223720|uniprotkb:B2RBG4|uniprotkb:Q8NEY6|uniprotkb:Q8IVY0|intact:MINT-2823375|intact:UNK-5358198|uniprotkb:Q5JZ94|uniprotkb:Q6P4B5|uniprotkb:Q0VAD0|uniprotkb:Q8N5Q3|uniprotkb:Q9Y3H5|uniprotkb:A4FTX2|intact:UNK-5480409|uniprotkb:Q8IVR9|ensembl:ENSP00000321449 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rrp7a_human(display_long)|uniprotkb:CGI-96(orf name)|uniprotkb:RRP7A(gene name)|psi-mi:RRP7A(display_short)|uniprotkb:Gastric cancer antigen Zg14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056518.2|ensembl:ENSG00000189306(gene)|ensembl:ENST00000323013(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024326|interpro:IPR034890|interpro:IPR035979|interpro:IPR040446|interpro:IPR040447|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - comment:mint|comment:homomint figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:8ydFaLpL9ttv+9iZyvaQf3GPWXg9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NWT1 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-7641942|ensembl:ENSP00000368887|ensembl:ENSP00000496482|uniprotkb:Q5T4J2|uniprotkb:Q96T87|intact:MINT-3057412|uniprotkb:Q96QJ8 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pk1ip_human(display_long)|uniprotkb:PAK1IP1(gene name)|psi-mi:PAK1IP1(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:WDR84(gene name synonym)|uniprotkb:PAK1-interacting protein 1(gene name synonym)|uniprotkb:PAK/PLC-interacting protein 1(gene name synonym)|uniprotkb:WD repeat-containing protein 84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000111845(gene)|ensembl:ENSG00000285226(gene)|ensembl:ENST00000379568(transcript)|ensembl:ENST00000644756(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NWT1|refseq:NP_060376.2 - - comment:mint|function:Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42 figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:nAGXksSPZ1aDBtcWOP59JX/lQGA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q14444 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|intact:EBI-3449178|uniprotkb:D3DR06|ensembl:ENSP00000340329|ensembl:ENSP00000434150 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_005889.3|refseq:NP_976240.1|ensembl:ENSG00000135387(gene)|ensembl:ENST00000341394(transcript)|ensembl:ENST00000532820(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0045202"(synapse)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|refseq:XP_016873238.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8NEJ9 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-9995414|uniprotkb:A8K760|uniprotkb:Q9Y400|ensembl:ENSP00000386134 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ngdn_human(display_long)|uniprotkb:NGDN(gene name)|psi-mi:NGDN(display_short)|uniprotkb:C14orf120(gene name synonym)|uniprotkb:Centromere accumulated nuclear protein 1(gene name synonym)|uniprotkb:EIF4E-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001036100.1|refseq:NP_056329.1|ensembl:ENSG00000129460(gene)|ensembl:ENST00000408901(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006417"(regulation of translation)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032040"(small-subunit processome)|interpro:IPR007146(Small-subunit processome, Utp3)|mint:Q8NEJ9 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:dzn7QntKCrb97VLlmUMizp+0CV49606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q14137 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1050828|uniprotkb:Q969Z6|uniprotkb:Q96IS8|uniprotkb:Q9BSA7|uniprotkb:Q9BVM0|ensembl:ENSP00000455106|ensembl:ENSP00000495401|uniprotkb:Q96Q25 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:bop1_human(display_long)|uniprotkb:Block of proliferation 1 protein(gene name synonym)|uniprotkb:BOP1(gene name)|psi-mi:BOP1(display_short)|uniprotkb:KIAA0124(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056016.1|ensembl:ENSG00000261236(gene)|ensembl:ENSG00000285301(gene)|ensembl:ENST00000569669(transcript)|ensembl:ENST00000642409(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR012953(BOP1, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028598|interpro:IPR036322|mint:Q14137|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:g2CwsRotXBvjvr+rSZSA0mKrVCY9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P49711 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P53621 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P11940 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P46013 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-876367|uniprotkb:Q5VWH2|ensembl:ENSP00000357643 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ki67_human(display_long)|uniprotkb:MKI67(gene name)|psi-mi:MKI67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001139438.1|refseq:NP_002408.3|dip:DIP-28132N|ensembl:ENSG00000148773(gene)|ensembl:ENST00000368654(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012568(K167R)|interpro:IPR029334|mint:P46013|rcsb pdb:1R21|rcsb pdb:2AFF|rcsb pdb:5J28 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:kyrLLOv4HSqah1Y6HtzebG978Kw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y2R4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-395458|uniprotkb:Q86YG1|uniprotkb:Q8N213|uniprotkb:Q9NVE0|uniprotkb:Q9Y482|ensembl:ENSP00000479504|ensembl:ENSP00000480030 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx52_human(display_long)|uniprotkb:DDX52(gene name)|psi-mi:DDX52(display_short)|uniprotkb:ROK1(gene name synonym)|uniprotkb:DEAD box protein 52(gene name synonym)|uniprotkb:ATP-dependent RNA helicase ROK1-like(gene name synonym)|uniprotkb:HUSSY-19(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_008941.3|ensembl:ENSG00000277594(gene)|ensembl:ENSG00000278053(gene)|ensembl:ENST00000615769(transcript)|ensembl:ENST00000617633(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044764|mint:Q9Y2R4|rcsb pdb:3DKP|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001278405.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:M3yY9StxHlLGPK0WOqPHwgnmwLU9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NZB2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|ensembl:ENSG00000048828(gene)|ensembl:ENST00000277165(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H6R4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2514288|ensembl:ENSP00000297990|uniprotkb:Q5T5M4|uniprotkb:Q8TEZ0|uniprotkb:Q8TEZ1|uniprotkb:Q8TEY9|uniprotkb:Q7L4G6|uniprotkb:Q5T5M3|uniprotkb:Q8N6I0|uniprotkb:Q9H675 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nol6_human(display_long)|uniprotkb:NOL6(gene name)|psi-mi:NOL6(display_short)|uniprotkb:Nucleolar RNA-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000165271(gene)|ensembl:ENST00000297990(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|interpro:IPR005554(Nrap protein)|interpro:IPR035082|interpro:IPR035367|interpro:IPR035368|interpro:IPR035369|interpro:IPR035370|interpro:IPR035371|mint:Q9H6R4|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_075068.2|refseq:NP_631981.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:e1Waxlhmq+KTKwHTV13aWEpVF4k9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8WTT2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2512539|ensembl:ENSP00000360412|uniprotkb:Q9H9D8|uniprotkb:Q9H5M6 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:noc3l_human(display_long)|uniprotkb:NOC3L(gene name)|psi-mi:NOC3L(display_short)|uniprotkb:AD24(gene name synonym)|uniprotkb:C10orf117(gene name synonym)|uniprotkb:FAD24(gene name synonym)|uniprotkb:NOC3-like protein(gene name synonym)|uniprotkb:Nucleolar complex-associated protein 3-like protein(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045444"(fat cell differentiation)|interpro:IPR005612(CBF)|interpro:IPR011501(Nucleolar complex-associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016903(Nucleolar complex-associated protein 3)|mint:Q8WTT2|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000173145(gene)|ensembl:ENST00000371361(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|refseq:NP_071896.8 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:s78IiBuQQjc0emiM/UkEMhzThVc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y3T9 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q14152 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O95478 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2852366|ensembl:ENSP00000483484 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nsa2_human(display_long)|uniprotkb:NSA2(gene name)|psi-mi:NSA2(display_short)|uniprotkb:TINP1(gene name synonym)|uniprotkb:Hairy cell leukemia protein 1(gene name synonym)|uniprotkb:TGF-beta-inducible nuclear protein 1(gene name synonym)|uniprotkb:HUSSY-29(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055701.1|refseq:NP_001258594.1|ensembl:ENSG00000164346(gene)|ensembl:ENST00000610426(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR022309|interpro:IPR039411|mint:O95478 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:UHmCVn1q0LfipKMzSFQUzmVULD49606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q92522 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NX58 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-713507|uniprotkb:Q6FI78|uniprotkb:Q9NYS1|ensembl:ENSP00000345917|ensembl:ENSP00000397367|uniprotkb:D3DVS4 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:lyar_human(display_long)|uniprotkb:LYAR(gene name)|psi-mi:LYAR(display_short)|uniprotkb:PNAS-5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000145220(gene)|ensembl:ENST00000343470(transcript)|ensembl:ENST00000452476(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|interpro:IPR041010|mint:Q9NX58|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZVH|refseq:NP_001139197.1|refseq:NP_060286.1|refseq:XP_011511807.1|refseq:XP_011511808.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:AJ+5B1LahcUlSWQehJ2vxY+8pwY9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q96GQ7 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-722051|uniprotkb:A0AVB6|uniprotkb:Q5VXM7|uniprotkb:Q8WYG4|uniprotkb:Q969N7|uniprotkb:Q96F57|uniprotkb:Q96L97|uniprotkb:Q9BWY9|uniprotkb:Q9BXF0|uniprotkb:Q9H990|uniprotkb:Q9NWU3|uniprotkb:Q9P0C2|uniprotkb:Q9UGD6|uniprotkb:B7ZLY1 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx27_human(display_long)|uniprotkb:DEAD box protein 27(gene name synonym)|uniprotkb:DDX27(gene name)|psi-mi:DDX27(display_short)|uniprotkb:RHLP(gene name synonym)|uniprotkb:cPERP-F(gene name synonym)|uniprotkb:HSPC259(orf name)|uniprotkb:PP3241(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG interpro:IPR027417|refseq:NP_060365.7|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|mint:Q96GQ7|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:Z4Dm6lxXyqB18+uPxROJszLWYdE9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H0D6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-372110|uniprotkb:Q3L8N4|uniprotkb:Q6KGZ9|uniprotkb:Q9BQL1|uniprotkb:Q9NTW0|uniprotkb:Q9NXS6|uniprotkb:Q9UL53|ensembl:ENSP00000366396 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:xrn2_human(display_long)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short)|uniprotkb:DHM1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_036387.2|refseq:NP_001304889.1|ensembl:ENSG00000088930(gene)|ensembl:ENST00000377191(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|mint:Q9H0D6|reactome:R-HSA-390471|reactome:R-HSA-6791226|dip:DIP-31166N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:Ui0NiU+fGe68hK5CYTolkhioQbQ9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q96PV6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|intact:EBI-28984630|ensembl:ENSP00000318374|ensembl:ENSP00000478337|ensembl:ENSP00000478975|ensembl:ENSP00000480663|uniprotkb:A0A087WTE7 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_443157.1|ensembl:ENSG00000167615(gene)|ensembl:ENSG00000274305(gene)|ensembl:ENSG00000276458(gene)|ensembl:ENSG00000276681(gene)|ensembl:ENST00000326764(transcript)|ensembl:ENST00000617180(transcript)|ensembl:ENST00000621306(transcript)|ensembl:ENST00000622672(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|mint:Q96PV6|ensembl:ENSP00000318374|ensembl:ENST00000610314|ensembl:ENSP00000484494|ensembl:ENST00000611866|ensembl:ENSP00000479293|ensembl:ENST00000616932|ensembl:ENSP00000477813|ensembl:ENSP00000480663|ensembl:ENST00000617420|ensembl:ENSP00000481040|ensembl:ENSP00000478337|ensembl:ENSP00000478975|refseq:XP_011524717.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:kwgKuV5NW0hITukndsYeyQHTdd09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8TED0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1048301|uniprotkb:Q6IA60|uniprotkb:Q96E08|uniprotkb:Q9H9F8|uniprotkb:B4DU75|uniprotkb:B4DXK8|ensembl:ENSP00000296792 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:utp15_human(display_long)|uniprotkb:UTP15(gene name)|psi-mi:UTP15(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001271359.1|refseq:NP_001271360.1|refseq:NP_115551.2|refseq:XP_011541982.1|ensembl:ENSG00000164338(gene)|ensembl:ENST00000296792(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018983|interpro:IPR019775|interpro:IPR036322|mint:Q8TED0|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:acCnB6DdQIhfvM1C9EQVQdoqHvo9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O00425 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NZI8 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P00491 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-712238|ensembl:ENSP00000354532|uniprotkb:Q15160|uniprotkb:Q5PZ03|uniprotkb:B2R8S5|uniprotkb:D3DS00 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pnph_human(display_long)|uniprotkb:Inosine phosphorylase(gene name synonym)|uniprotkb:PNP(gene name)|psi-mi:PNP(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Inosine-guanosine phosphorylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG go:"GO:0001882"(nucleoside binding)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006148"(inosine catabolic process)|go:"GO:0006149"(deoxyinosine catabolic process)|go:"GO:0006157"(deoxyadenosine catabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0006738"(nicotinamide riboside catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043101"(purine-containing compound salvage)|go:"GO:0046059"(dAMP catabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR011268(Inosine guanosine and xanthosine phosphorylase)|interpro:IPR011270(Purine nucleoside phosphorylase I, inosine and guanosine-specific)|interpro:IPR018099|interpro:IPR035994|mint:P00491|rcsb pdb:1M73|rcsb pdb:1PF7|rcsb pdb:1PWY|rcsb pdb:1RCT|rcsb pdb:1RFG|rcsb pdb:1RR6|rcsb pdb:1RSZ|rcsb pdb:1RT9|rcsb pdb:1ULA|rcsb pdb:1ULB|rcsb pdb:1V2H|rcsb pdb:1V3Q|rcsb pdb:1V41|rcsb pdb:1V45|rcsb pdb:1YRY|rcsb pdb:2A0W|rcsb pdb:2A0X|rcsb pdb:2A0Y|rcsb pdb:2OC4|rcsb pdb:2OC9|rcsb pdb:2ON6|rcsb pdb:2Q7O|rcsb pdb:3BGS|rcsb pdb:3D1V|rcsb pdb:3GB9|rcsb pdb:3GGS|ensembl:ENSG00000198805(gene)|ensembl:ENST00000361505(transcript)|go:"GO:0000255"(allantoin metabolic process)|rcsb pdb:3K8O|rcsb pdb:3K8Q|rcsb pdb:3PHB|rcsb pdb:4EAR|rcsb pdb:3INY|rcsb pdb:4EB8|rcsb pdb:4ECE|rcsb pdb:4GKA|rcsb pdb:5ETJ|rcsb pdb:5UGF|reactome:R-HSA-6798695|reactome:R-HSA-74217|reactome:R-HSA-74259|refseq:NP_000261.2|dip:DIP-50406N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:FOpaxV/M6HIA+THugPZDfN1ej1o9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y4C8 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-5453906|uniprotkb:Q9BPY6|uniprotkb:Q9UFN5|uniprotkb:A8K5X9|ensembl:ENSP00000261741|ensembl:ENSP00000376344|ensembl:ENSP00000442053 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rbm19_human(display_long)|uniprotkb:RBM19(gene name)|psi-mi:RBM19(display_short)|uniprotkb:KIAA0682(gene name synonym)|uniprotkb:RNA-binding motif protein 19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001140170.1|refseq:NP_001140171.1|refseq:NP_057280.2|ensembl:ENSG00000122965(gene)|ensembl:ENST00000261741(transcript)|ensembl:ENST00000392561(transcript)|ensembl:ENST00000545145(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0040019"(positive regulation of embryonic development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034417|interpro:IPR034418|interpro:IPR034419|interpro:IPR034420|interpro:IPR034421|interpro:IPR034423|interpro:IPR035979|rcsb pdb:2DGW - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:zWHweYT/J/490xVMEjzNpqi+SK49606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q5RKV6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2841747|ensembl:ENSP00000398597 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q14684 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q96SI9 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-740355|uniprotkb:Q32NB9|uniprotkb:Q9BUE1|uniprotkb:Q9BXG4|uniprotkb:Q9H0B4|uniprotkb:Q9H7V1|uniprotkb:Q9NUK4|ensembl:ENSP00000321347|ensembl:ENSP00000415968 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:strbp_human(display_long)|uniprotkb:STRBP(gene name)|psi-mi:STRBP(display_short)|uniprotkb:SPNR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001164608.1|refseq:NP_060857.2|ensembl:ENSG00000165209(gene)|ensembl:ENST00000348403(transcript)|ensembl:ENST00000447404(transcript)|go:"GO:0002177"(manchette)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0008017"(microtubule binding)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR030446|interpro:IPR043519|interpro:IPR044472|rcsb pdb:2DMY|refseq:XP_016870383.1|refseq:XP_016870384.1|refseq:XP_016870385.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:xVEZqCqBcH0MBB1Ar9SU+9Yhsbs9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q14146 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-9996029|uniprotkb:Q5VYC9|ensembl:ENSP00000258243 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:urb2_human(display_long)|uniprotkb:URB2(gene name)|psi-mi:URB2(display_short)|uniprotkb:KIAA0133(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055592.2|refseq:NP_001300950.1|ensembl:ENSG00000135763(gene)|ensembl:ENST00000258243(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0016235"(aggresome)|go:"GO:0030496"(midbody)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR018849 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:BhDO5U3/iVSj0xlncOQpkGRl+gc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H6R0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2512405|ensembl:ENSP00000225296|uniprotkb:Q4G149|uniprotkb:B4DHF9|uniprotkb:Q5CZ73|uniprotkb:Q9H5M9 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:dhx33_human(display_long)|uniprotkb:DHX33(gene name)|psi-mi:DHX33(display_short)|uniprotkb:DDX33(gene name synonym)|uniprotkb:DEAH box protein 33(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000005100(gene)|ensembl:ENST00000225296(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q9H6R0|refseq:NP_001186628.1|refseq:NP_064547.2|refseq:XP_016880366.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:jR/BdCPb1fZgJxOWaxNRfqo0AvQ9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q5SSJ5 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2880687|ensembl:ENSP00000312625|ensembl:ENSP00000403039|uniprotkb:Q5SWC6|uniprotkb:Q6PIM9|uniprotkb:B3KMZ8|uniprotkb:A8K5D7|uniprotkb:Q8NDF0|uniprotkb:Q05BI0|uniprotkb:B4E210|uniprotkb:A6NI71|uniprotkb:Q9UHY0|uniprotkb:Q5SSJ6 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:hp1b3_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short)|uniprotkb:Protein HP1-BP74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000127483(gene)|ensembl:ENST00000312239(transcript)|ensembl:ENST00000438032(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|mint:Q5SSJ5|rcsb pdb:2RQP|go:"GO:0005694"(chromosome)|refseq:XP_016856882.1|refseq:XP_016856883.1|refseq:XP_011539834.1|refseq:XP_011539835.1|refseq:XP_011539836.1|refseq:NP_057371.2|refseq:XP_005245932.1|refseq:XP_005245933.1|refseq:XP_005245934.1|refseq:XP_005245935.1|refseq:XP_005245936.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:kLFithZZv+Qn9YLElEnX81awKDw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8IWA0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2515097|ensembl:ENSP00000314193|uniprotkb:Q9UIX2|uniprotkb:Q9H9U5|uniprotkb:Q96J10|uniprotkb:Q9H8U8|uniprotkb:Q9H9V8 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:wdr75_human(display_long)|uniprotkb:WDR75(gene name)|psi-mi:WDR75(display_short)|uniprotkb:UTP17(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 17 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000115368(gene)|ensembl:ENST00000314761(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_115544.1|refseq:NP_001290025.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:qAYPzmryYALOzvea97t1q/NCsVs9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q1ED39 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-9977982|uniprotkb:O43328|uniprotkb:Q5FWF3|ensembl:ENSP00000219837 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:knop1_human(display_long)|uniprotkb:KNOP1(gene name)|psi-mi:KNOP1(display_short)|uniprotkb:C16orf88(gene name synonym)|uniprotkb:FAM191A(gene name synonym)|uniprotkb:TSG118(gene name synonym)|uniprotkb:Protein FAM191A(gene name synonym)|uniprotkb:Testis-specific gene 118 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001013009.2|refseq:NP_001335457.1|refseq:NP_001335458.1|refseq:NP_001335459.1|refseq:NP_001335460.1|ensembl:ENSG00000103550(gene)|ensembl:ENST00000219837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR028124 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:DbTowYDo0km0cUlAS8TTL5JIyyQ9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q13206 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2514399|ensembl:ENSP00000314348|uniprotkb:Q5BJD8|uniprotkb:B2RCQ3 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx10_human(display_long)|uniprotkb:DDX10(gene name)|psi-mi:DDX10(display_short)|uniprotkb:DEAD box protein 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000178105(gene)|ensembl:ENST00000322536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0097065"(anterior head development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|mint:Q13206|rcsb pdb:2PL3|refseq:NP_004389.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:MMAbABrYQHlYDyPsagT7oY92Z3M9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q7L2E3 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1211456|uniprotkb:O94965|uniprotkb:Q7Z753|uniprotkb:Q96CH4|uniprotkb:Q9NUQ0|uniprotkb:A8K5F1|ensembl:ENSP00000392601|ensembl:ENSP00000405620|intact:EBI-21350949 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:dhx30_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short)|uniprotkb:KIAA0890(gene name synonym)|uniprotkb:DDX30(gene name synonym)|uniprotkb:DEAH box protein 30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055781.2|refseq:NP_619520.1|refseq:XP_011531796.1|refseq:XP_011531797.1|refseq:XP_016861406.1|ensembl:ENSG00000132153(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q7L2E3|rcsb pdb:2DB2|ensembl:ENST00000445061(transcript)|ensembl:ENST00000446256(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:tb4GzZKLycraXS0NlVqj8reV3IQ9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NPE3 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1642169|ensembl:ENSP00000332198 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nop10_human(display_long)|uniprotkb:NOLA3(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:Nucleolar protein 10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_061118.1|dip:DIP-40092N|ensembl:ENSG00000182117(gene)|ensembl:ENST00000328848(transcript)|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016604"(nuclear body)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|mint:Q9NPE3|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:gBAwyGcfJTBMf8Q+fQZ/fDcPEBc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8IY81 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-744088|uniprotkb:Q8N3A3|uniprotkb:Q8WXX1|uniprotkb:Q9BWM4|uniprotkb:Q9NXT6|uniprotkb:D3DU22|uniprotkb:B2RCA5|ensembl:ENSP00000396673 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:spb1_human(display_long)|uniprotkb:FTSJ3(gene name)|psi-mi:FTSJ3(display_short)|uniprotkb:SB92(orf name)|uniprotkb:Protein ftsJ homolog 3(gene name synonym)|uniprotkb:Putative rRNA methyltransferase 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_060117.3|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR024576|interpro:IPR028589|interpro:IPR029063|mint:Q8IY81|reactome:R-HSA-6791226|ensembl:ENSG00000108592(gene)|ensembl:ENST00000427159(transcript)|go:"GO:0000453"(enzyme-directed rRNA 2'-O-methylation)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008650"("rRNA (uridine-2'-O-)-methyltransferase activity")|go:"GO:0016435"("rRNA (guanine) methyltransferase activity")|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0031167"(rRNA methylation)|go:"GO:0062105"(RNA 2'-O-methyltransferase activity)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR012920(Spb1, C-terminal) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:KIeyMWn9Zktm5lV7XI7v2bRA8og9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P42285 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BRJ6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-751612|ensembl:ENSP00000350011|ensembl:ENSP00000380286|ensembl:ENSP00000380288 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:cg050_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_115726.1|refseq:NP_001305181.1|ensembl:ENSG00000146540(gene)|ensembl:ENST00000357429(transcript)|ensembl:ENST00000397098(transcript)|ensembl:ENST00000397100(transcript)|interpro:IPR019327|mint:Q9BRJ6|go:"GO:0003723"(RNA binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P10412 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-358163|uniprotkb:Q4VB25|ensembl:ENSP00000307705 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:h14_human(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1F4(gene name synonym)|uniprotkb:HIST1H1E(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_005312.1|rcsb pdb:6H8P|rcsb pdb:7K5Y|rcsb pdb:7K63|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10412|rcsb pdb:3TZD|rcsb pdb:5JJZ|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000168298(gene)|ensembl:ENST00000304218(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:yT8wBbspLLR8G3DrgpFeWEOPgac9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NQT5 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9P275 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2512419|ensembl:ENSP00000310590|ensembl:ENSP00000441214|ensembl:ENSP00000467280|uniprotkb:Q8NDM8|uniprotkb:Q05DD0|uniprotkb:Q9NVC8|uniprotkb:Q05C98|uniprotkb:Q6IQ38 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ubp36_human(display_long)|uniprotkb:USP36(gene name)|psi-mi:USP36(display_short)|uniprotkb:KIAA1453(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 36(gene name synonym)|uniprotkb:Deubiquitinating enzyme 36(gene name synonym)|uniprotkb:Ubiquitin thioesterase 36(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000055483(gene)|ensembl:ENST00000312010(transcript)|ensembl:ENST00000542802(transcript)|ensembl:ENST00000589225(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007000"(nucleolus organization)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000232"(regulation of rRNA processing)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|refseq:XP_005257599.1|refseq:XP_005257600.1|refseq:XP_016880389.1|refseq:NP_001308220.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:91IyxhRDumStuUMNS8qNaB8SUMA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9GZR7 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H0S4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2515241|ensembl:ENSP00000350698|uniprotkb:Q96NV8|uniprotkb:B3KXP4|uniprotkb:Q96GM0|uniprotkb:G5E955|uniprotkb:Q9UI98 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx47_human(display_long)|uniprotkb:DDX47(gene name)|psi-mi:DDX47(display_short)|uniprotkb:DEAD box protein 47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000213782(gene)|ensembl:ENST00000358007(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044765|mint:Q9H0S4|rcsb pdb:3BER|reactome:R-HSA-6790901|reactome:R-HSA-6791226|interpro:IPR014001(DEAD-like helicase, N-terminal)|refseq:NP_057439.2|refseq:NP_957518.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:AhH5kg/8cw6L5385wUw4PR243rY9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y5J1 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-592816|uniprotkb:Q9H4N6|ensembl:ENSP00000225298 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:utp18_human(display_long)|uniprotkb:WD repeat-containing protein 50(gene name synonym)|uniprotkb:UTP18(gene name)|psi-mi:UTP18(display_short)|uniprotkb:CGI-48(orf name)|uniprotkb:CDABP0061(orf name)|uniprotkb:WDR50(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_057085.2|ensembl:ENSG00000011260(gene)|ensembl:ENST00000225298(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9Y5J1|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:l873IUyfCql4N9VelHPuUEqpzRY9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BXY0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-5280229|uniprotkb:B2RB44|uniprotkb:Q5U5T1|uniprotkb:Q86UC4|uniprotkb:Q96SY6|ensembl:ENSP00000353246 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:mak16_human(display_long)|uniprotkb:MAK16(gene name)|psi-mi:MAK16(display_short)|uniprotkb:RBM13(gene name synonym)|uniprotkb:NNP78(gene name synonym)|uniprotkb:Protein RBM13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_115898.2|ensembl:ENSG00000198042(gene)|ensembl:ENST00000360128(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR006958(Mak16 protein)|interpro:IPR029004|mint:Q9BXY0 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:Zedk3AV8WcIUeBxPWbFlL6HztIA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H6F5 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-721289|uniprotkb:B4DY99|ensembl:ENSP00000227520 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ccd86_human(display_long)|uniprotkb:Cytokine-induced protein with coiled-coil domain(gene name synonym)|uniprotkb:CYCLON(gene name synonym)|uniprotkb:CCDC86(gene name)|psi-mi:CCDC86(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_077003.1|ensembl:ENSG00000110104(gene)|ensembl:ENST00000227520(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR005579(Cgr1)|interpro:IPR026570|mint:Q9H6F5 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:dRd5UWPzAehh8OFqkWrMMCnYYug9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8TDD1 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:VzxEkRaOIND08jGJk3yyoztesjo9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O15381 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-721638|uniprotkb:Q96EM7|uniprotkb:B4DMC4|uniprotkb:B4DP98|ensembl:ENSP00000281701 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nvl_human(display_long)|uniprotkb:NVL(gene name)|psi-mi:NVL(display_short)|uniprotkb:NVL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_002524.2|refseq:NP_996671.1|refseq:NP_001230075.1|refseq:NP_001230076.1|ensembl:ENSG00000143748(gene)|ensembl:ENST00000281701(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1904749"(regulation of protein localization to nucleolus)|go:"GO:1990275"(preribosome binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR031996|interpro:IPR038100|interpro:IPR041569|mint:O15381|rcsb pdb:2X8A|rcsb pdb:6RO1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:3xAHor7LoQCGSzrRQWhKaEuqd9A9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NW13 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2878099|ensembl:ENSP00000223073|uniprotkb:Q96CV3|uniprotkb:A4D100|uniprotkb:Q53H65|uniprotkb:B4DU52|uniprotkb:E9PDD9 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rbm28_human(display_long)|uniprotkb:RBM28(gene name)|psi-mi:RBM28(display_short)|uniprotkb:RNA-binding motif protein 28(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9NW13|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000106344(gene)|ensembl:ENST00000223073(transcript)|refseq:NP_001159607.1|refseq:NP_060547.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:yIPQX+d5YQpq3gpdtBilOXJcUsg9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O75683 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2691252|uniprotkb:Q9UK24|uniprotkb:Q9BTZ5|uniprotkb:Q5T8U1|uniprotkb:Q9BRK9|ensembl:ENSP00000361092|ensembl:ENSP00000485909 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:surf6_human(display_long)|uniprotkb:SURF-6(gene name synonym)|uniprotkb:SURF6(gene name)|psi-mi:SURF6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_006744.2|refseq:NP_001265871.1|ensembl:ENSG00000148296(gene)|ensembl:ENSG00000281309(gene)|ensembl:ENST00000372022(transcript)|ensembl:ENST00000629980(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007019(Surfeit locus 6)|interpro:IPR029190 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:1Yzf0+p31xuzJXSoaiz9THfjF0c9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q13895 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-358049|uniprotkb:Q6P5W4|uniprotkb:Q86W44|uniprotkb:Q96IP8|ensembl:ENSP00000230340 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:byst_human(display_long)|uniprotkb:BYSL(gene name)|psi-mi:BYSL(display_short)|uniprotkb:ENP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_004044.3|dip:DIP-50092N|ensembl:ENSG00000112578(gene)|ensembl:ENST00000230340(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045177"(apical part of cell)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR007955(Bystin)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:QdpF9XYm2gFc5ZodqaGvqTM6XNk9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P62140 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P18827 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2855248|uniprotkb:Q53QV0|uniprotkb:Q96HB7|uniprotkb:Q546D3|uniprotkb:D6W523|ensembl:ENSP00000254351|ensembl:ENSP00000370542 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:sdc1_human(display_long)|uniprotkb:SDC1(gene name)|psi-mi:SDC1(display_short)|uniprotkb:SDC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001006947.1|refseq:NP_002988.3|dip:DIP-1123N|ensembl:ENSG00000115884(gene)|ensembl:ENST00000254351(transcript)|ensembl:ENST00000381150(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0048627"(myoblast development)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055002"(striated muscle cell development)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031190|mint:P18827|rcsb pdb:4GVC|rcsb pdb:4GVD|rcsb pdb:6EJE|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3000170|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-449836|reactome:R-HSA-975634|go:"GO:0042476"(odontogenesis)|go:"GO:0042542"(response to hydrogen peroxide) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:SyiC0eBqj/X5xsWqRy9EWDxlmH09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NUL3 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-722938|uniprotkb:Q6AHY7|uniprotkb:Q96HM0|uniprotkb:Q96HM1|uniprotkb:Q9NVI5|uniprotkb:Q9UGG6|uniprotkb:A0A0A0MTC5|uniprotkb:E9PF26|uniprotkb:B7Z1I6|uniprotkb:B7Z292|uniprotkb:B7Z8B4|uniprotkb:E7ER74|uniprotkb:E9PEI3|uniprotkb:E9PF50|ensembl:ENSP00000428756 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:stau2_human(display_long)|uniprotkb:STAU2(gene name)|psi-mi:STAU2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001157852.1|refseq:NP_001157853.1|refseq:NP_001157854.1|refseq:NP_001157855.1|refseq:NP_001157856.1|refseq:NP_001157857.1|refseq:NP_055208.2|ensembl:ENSG00000040341(gene)|ensembl:ENST00000524300(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044464|interpro:IPR044473|interpro:IPR044474|interpro:IPR044476 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:iFcd8pLhQK+8ihFUCf4sl2f0bgw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q5SY16 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1055462|uniprotkb:Q4VBY3|uniprotkb:Q6P472|uniprotkb:Q7L4D6|uniprotkb:Q96EE0|uniprotkb:Q9H5L4|uniprotkb:Q2NL84|ensembl:ENSP00000366934 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nol9_human(display_long)|uniprotkb:NOL9(gene name)|psi-mi:NOL9(display_short)|uniprotkb:Nucleolar protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_078930.3|refseq:XP_011540449.1|ensembl:ENST00000377705(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|interpro:IPR027417|interpro:IPR032319|mint:Q5SY16|reactome:R-HSA-6791226|ensembl:ENSG00000162408(gene)|refseq:XP_016857827.1|refseq:XP_016857828.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:IWGhuh/G+MlTxlSXEcIml8tvK7Y9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q13823 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1043365|uniprotkb:Q9BWN7|ensembl:ENSP00000362153 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nog2_human(display_long)|uniprotkb:Autoantigen NGP-1(gene name synonym)|uniprotkb:GNL2(gene name)|psi-mi:GNL2(display_short)|uniprotkb:NGP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000134697(gene)|ensembl:ENST00000373062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q13823|rcsb pdb:6LSS|rcsb pdb:6LU8|refseq:NP_037417.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:CgIg/QNhk71SHIhV4iLvIuC/HUo9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q6PKG0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y462 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2849152|uniprotkb:Q9Y4J6|uniprotkb:Q6NX42|uniprotkb:B4DSV4|ensembl:ENSP00000276123|ensembl:ENSP00000362260 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:zn711_human(display_long)|uniprotkb:ZNF711(gene name)|psi-mi:ZNF711(display_short)|uniprotkb:CMPX1(gene name synonym)|uniprotkb:ZNF6(gene name synonym)|uniprotkb:Zinc finger protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:XP_011529326.1|refseq:XP_011529328.1|refseq:NP_068838.3|refseq:XP_005262243.1|refseq:XP_005262244.1|refseq:XP_005262245.1|refseq:XP_005262246.1|refseq:NP_001317503.1|refseq:XP_016885294.1|refseq:XP_016885295.1|refseq:XP_016885296.1|refseq:XP_016885297.1|refseq:XP_016885298.1|ensembl:ENSG00000147180(gene)|ensembl:ENST00000276123(transcript)|ensembl:ENST00000373165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR006794(Zfx / Zfy transcription activation region)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:+D8I1UK1AkHcgA4oKgk04+/Spvg9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NUQ6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-5280638|uniprotkb:A8K381|uniprotkb:B7WNZ7|uniprotkb:Q53T22|uniprotkb:Q8WV53|uniprotkb:Q8WYG1|uniprotkb:Q9NTW4|uniprotkb:B4DRE6|uniprotkb:B4DT67|ensembl:ENSP00000351503|ensembl:ENSP00000386336|ensembl:ENSP00000386730|ensembl:ENSP00000386931|ensembl:ENSP00000391467 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:sps2l_human(display_long)|uniprotkb:SPATS2L(gene name)|psi-mi:SPATS2L(display_short)|uniprotkb:DNAPTP6(gene name synonym)|uniprotkb:DNA polymerase-transactivated protein 6(gene name synonym)|uniprotkb:Stress granule and nucleolar protein(gene name synonym)|uniprotkb:SP1224(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001269664.1|refseq:NP_001269672.1|refseq:XP_011509240.1|refseq:XP_011509241.1|refseq:NP_001093892.1|refseq:NP_001093893.1|refseq:NP_001093894.1|refseq:NP_056350.2|refseq:XP_005246513.1|refseq:XP_005246514.1|refseq:XP_005246515.1|refseq:XP_005246516.1|refseq:NP_001269673.1|refseq:XP_016859272.1|refseq:XP_016859274.1|refseq:XP_016859275.1|refseq:XP_016859276.1|ensembl:ENSG00000196141(gene)|ensembl:ENST00000358677(transcript)|ensembl:ENST00000409140(transcript)|ensembl:ENST00000409718(transcript)|ensembl:ENST00000409988(transcript)|ensembl:ENST00000451764(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|interpro:IPR009060(UBA-like)|interpro:IPR009816(Protein of unknown function DUF1387)|mint:Q9NUQ6 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:B+nzSpiu2ECSVNxsajBSZrk6dhA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q15024 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H9Y2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-9996007|uniprotkb:Q5VSK7|uniprotkb:Q6AHX1|uniprotkb:Q8WXZ8|ensembl:ENSP00000359688 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rpf1_human(display_long)|uniprotkb:RPF1(gene name)|psi-mi:RPF1(display_short)|uniprotkb:BXDC5(gene name synonym)|uniprotkb:Brix domain-containing protein 5(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_079341.2|ensembl:ENSG00000117133(gene)|ensembl:ENST00000370654(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR044281|go:"GO:0000460"(maturation of 5.8S rRNA) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:lPJHR67nRalKzyv8rBOSx3duAvE9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O75691 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-356062|uniprotkb:Q9H3H4|ensembl:ENSP00000261637 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:utp20_human(display_long)|uniprotkb:UTP20(gene name)|psi-mi:UTP20(display_short)|uniprotkb:DRIM(gene name synonym)|uniprotkb:Down-regulated in metastasis protein(gene name synonym)|uniprotkb:Protein Key-1A6(gene name synonym)|uniprotkb:Novel nucleolar protein 73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055318.2|ensembl:ENSG00000120800(gene)|ensembl:ENST00000261637(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|interpro:IPR011430(Down-regulated in metastasis)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:OxTEfw2MtOijthWHjRtqIqUUjjg9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BZE4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1056249|uniprotkb:O95446|uniprotkb:Q9NVJ8|uniprotkb:B3KMC5|uniprotkb:B4DY13|uniprotkb:B7Z7A3|uniprotkb:Q5T3R8|ensembl:ENSP00000354040 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:gtpb4_human(display_long)|uniprotkb:GTPBP4(gene name)|psi-mi:GTPBP4(display_short)|uniprotkb:CRFG(gene name synonym)|uniprotkb:NOG1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_036473.2|ensembl:ENSG00000107937(gene)|ensembl:ENST00000360803(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q9BZE4|rcsb pdb:6LSS|rcsb pdb:6LU8 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:wTcBrIj6c27um4RnJH81grRgutc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O15234 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-299118|ensembl:ENSP00000264645|uniprotkb:A8K8R0 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:casc3_human(display_long)|uniprotkb:CASC3(gene name)|psi-mi:CASC3(display_short)|uniprotkb:MLN51(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 3 protein(gene name synonym)|uniprotkb:Metastatic lymph node gene 51 protein(gene name synonym)|uniprotkb:Protein barentsz(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR018545|interpro:IPR028544|ensembl:ENSG00000108349(gene)|ensembl:ENST00000264645(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_031385.2|refseq:XP_005257220.1|dip:DIP-33288N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:62nwK5KCrjsyaY7WKPlfUAPhohM9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q15050 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-749186|uniprotkb:Q9BUX8|ensembl:ENSP00000322396 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rrs1_human(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:KIAA0112(gene name synonym)|uniprotkb:RRR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055984.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|mint:Q15050|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000179041(gene)|ensembl:ENST00000320270(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:0Nm9UoIGLBiqOGl0E2BA0S5EXIU9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q13610 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1050630|uniprotkb:A8K3R6|ensembl:ENSP00000387365|uniprotkb:Q7Z3X9 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045(gene)|ensembl:ENST00000412830(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P13797 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-698052|uniprotkb:B1AQ09|uniprotkb:Q86YI6|uniprotkb:A8K579|uniprotkb:B4DGB4|uniprotkb:B7Z6M1|ensembl:ENSP00000348163|ensembl:ENSP00000445339 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:plst_human(display_long)|uniprotkb:T-plastin(gene name synonym)|uniprotkb:PLS3(gene name)|psi-mi:PLS3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001129497.1|refseq:NP_005023.2|refseq:XP_011535836.1|refseq:NP_001165806.1|refseq:NP_001269266.1|refseq:NP_001269267.1|ensembl:ENSG00000102024(gene)|ensembl:ENST00000355899(transcript)|ensembl:ENST00000539310(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032432"(actin filament bundle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:P13797|rcsb pdb:1AOA|rcsb pdb:1WJO - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:RWAS8uhDHEtqdDd1gfsqDDyvvsE9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8NDF8 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2803971|uniprotkb:Q9NW67|uniprotkb:Q9Y6C0|uniprotkb:B4DV38 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:papd5_human(display_long)|uniprotkb:"Non-canonical poly(A) RNA polymerase PAPD5"(gene name synonym)|uniprotkb:TUT3(gene name synonym)|uniprotkb:Terminal guanylyltransferase(gene name synonym)|uniprotkb:TENT4B(gene name)|psi-mi:TENT4B(display_short)|uniprotkb:GLD4(gene name synonym)|uniprotkb:PAP-associated domain-containing protein 5(gene name synonym)|uniprotkb:PAPD5(gene name synonym)|uniprotkb:TRF4-2(gene name synonym)|uniprotkb:Terminal uridylyltransferase 3(gene name synonym)|uniprotkb:Topoisomerase-related function protein 4-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001035375.2|refseq:NP_001035374.2|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031499"(TRAMP complex)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033500"(carbohydrate homeostasis)|go:"GO:0043629"(ncRNA polyadenylation)|go:"GO:0043630"(ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0060212"("negative regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070568"(guanylyltransferase activity)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071050"("sno(s)RNA polyadenylation")|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR040136|interpro:IPR043519|dip:DIP-59183N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:Dy+EsRClygf3oq2i8AdtST3ENS49606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q4G0J3 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-2560173|ensembl:ENSP00000314311|ensembl:ENSP00000344950|ensembl:ENSP00000499190 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056269.1|refseq:NP_057732.2|refseq:NP_001253968.1|dip:DIP-47624N|ensembl:ENSG00000174720(gene)|ensembl:ENST00000324052(transcript)|ensembl:ENST00000344442(transcript)|ensembl:ENST00000651579(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H6S0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1057466|uniprotkb:B2RP66|ensembl:ENSP00000161863 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ytdc2_human(display_long)|uniprotkb:YTHDC2(gene name)|psi-mi:YTHDC2(display_short)|uniprotkb:YTH domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_073739.3|ensembl:ENSG00000047188(gene)|ensembl:ENST00000161863(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007286"(spermatid development)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048599"(oocyte development)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051729"(germline cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031083|interpro:IPR034083|interpro:IPR036770|interpro:IPR036867|mint:Q9H6S0|rcsb pdb:2YU6|rcsb pdb:6K6U|refseq:XP_016865219.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:8J8b1Q3F6rfXUwtp7EOeU2y89Lc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P36873 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-356283|ensembl:ENSP00000335084 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y4W2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O00541 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1053271|uniprotkb:Q6IC29|ensembl:ENSP00000346725 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pesc_human(display_long)|uniprotkb:PES1(gene name)|psi-mi:PES1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001230154.1|refseq:NP_055118.1|ensembl:ENSG00000100029(gene)|ensembl:ENST00000354694(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:2EP8|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:Nq1SJ37kJfe+vF9zmNASz1gnbfY9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H9L3 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-751335|uniprotkb:Q64KA2|uniprotkb:D3DVC6|ensembl:ENSP00000323424|ensembl:ENSP00000357202 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:i20l2_human(display_long)|uniprotkb:ISG20L2(gene name)|psi-mi:ISG20L2(display_short)|uniprotkb:HSD38(orf name)|uniprotkb:HSD-38(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001290024.1|refseq:XP_005245573.1|refseq:XP_006711623.1|refseq:XP_006711624.1|reactome:R-HSA-6791226|interpro:IPR037433|mint:Q9H9L3|ensembl:ENSG00000143319(gene)|ensembl:ENST00000313146(transcript)|ensembl:ENST00000368219(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034933|interpro:IPR036397 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:i/TZBz8UuJIRm7WZZKjHYU75AS89606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q13310 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q5T3I0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2372076|uniprotkb:Q5T3I1|uniprotkb:Q6ZUE7|uniprotkb:Q8IWG8|uniprotkb:Q9NXH4 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:gptc4_human(display_long)|uniprotkb:GPATCH4(gene name)|psi-mi:GPATCH4(display_short)|uniprotkb:GPATC4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG interpro:IPR000467(D111/G-patch)|mint:Q5T3I0|go:"GO:0003723"(RNA binding) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:R2hFHYGQh2jmLbLg+BNATVimtNA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q15397 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-725523|uniprotkb:Q547G7|uniprotkb:Q5SZY9|uniprotkb:Q6IB47|uniprotkb:Q96B27|uniprotkb:Q96L78|uniprotkb:Q96L79|uniprotkb:Q96L80|uniprotkb:A8K804|ensembl:ENSP00000380982 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pum3_human(display_long)|uniprotkb:PUM3(gene name)|psi-mi:PUM3(display_short)|uniprotkb:cPERP-C(gene name synonym)|uniprotkb:HBV X-transactivated gene 5 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 5(gene name synonym)|uniprotkb:KIAA0020(gene name synonym)|uniprotkb:Minor histocompatibility antigen HA-8(gene name synonym)|uniprotkb:PUF-A(gene name synonym)|uniprotkb:XTP5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055693.4|ensembl:ENSG00000080608(gene)|ensembl:ENST00000397885(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006417"(regulation of translation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012959(CPL)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR040059|mint:Q15397|rcsb pdb:4WZR|rcsb pdb:4WZW - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:CjfVWg+3P3ai0EiHgeH8usbvgxg9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9HCE1 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O76021 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O96028 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P46087 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-356811|uniprotkb:A1A4Z3|uniprotkb:Q0P5S5|uniprotkb:Q58F30|uniprotkb:B3KPD6|uniprotkb:Q05BA7|uniprotkb:Q3KQS4|ensembl:ENSP00000313272|ensembl:ENSP00000444437 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nop2_human(display_long)|uniprotkb:NOP2(gene name)|psi-mi:NOP2(display_short)|uniprotkb:NSUN1(gene name synonym)|uniprotkb:Proliferating-cell nucleolar antigen p120(gene name synonym)|uniprotkb:Proliferation-associated nucleolar protein p120(gene name synonym)|uniprotkb:NOL1(gene name synonym)|uniprotkb:Nucleolar protein 2 homolog(gene name synonym)|uniprotkb:Nucleolar protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001028886.1|refseq:NP_006161.2|refseq:NP_001245237.1|refseq:NP_001245238.1|refseq:NP_001245239.1|refseq:XP_005253748.1|ensembl:ENSG00000111641(gene)|ensembl:ENST00000322166(transcript)|ensembl:ENST00000537442(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR012586(P120R)|interpro:IPR018314|interpro:IPR023267|interpro:IPR023273|interpro:IPR029063|interpro:IPR031341|mint:P46087|reactome:R-HSA-6790901|reactome:R-HSA-8869496 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:CvYaCDv8N8OvS0lPFy8jFEFaOTA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NQ55 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1048540|uniprotkb:Q9BW97|uniprotkb:Q9H170|uniprotkb:C9J3F9|ensembl:ENSP00000253107 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ssf1_human(display_long)|uniprotkb:Peter Pan homolog(gene name synonym)|uniprotkb:PPAN(gene name)|psi-mi:PPAN(display_short)|uniprotkb:SSF1(gene name synonym)|uniprotkb:BXDC3(gene name synonym)|uniprotkb:Brix domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001035754.1|refseq:NP_064615.3|ensembl:ENSG00000130810(gene)|ensembl:ENST00000253107(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR007109(Brix)|mint:Q9NQ55 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:wIgMQj/xJrj5eExsyZD6BeamQOQ9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H8H0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BQ67 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-351000|uniprotkb:Q8TF59|ensembl:ENSP00000253237|intact:EBI-9512815|uniprotkb:A0MNN5 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:grwd1_human(display_long)|uniprotkb:GRWD1(gene name)|psi-mi:GRWD1(display_short)|uniprotkb:GRWD(gene name synonym)|uniprotkb:WDR28(gene name synonym)|uniprotkb:KIAA1942(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG interpro:IPR022052|refseq:NP_113673.3|ensembl:ENSG00000105447(gene)|ensembl:ENST00000253237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|mint:Q9BQ67|interpro:IPR036322 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:rbkcKHsv+l3kFqh4SElBDft0b+A9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P56182 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q14692 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2513630|ensembl:ENSP00000363642|uniprotkb:Q86XJ9|uniprotkb:Q5QPT5 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:bms1_human(display_long)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)|uniprotkb:BMS1L(gene name synonym)|uniprotkb:KIAA0187(gene name synonym)|uniprotkb:Ribosome assembly protein BMS1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000165733(gene)|ensembl:ENST00000374518(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0030686"(90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|mint:Q14692|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|refseq:XP_011538704.1|refseq:NP_055568.3|refseq:XP_005271903.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:9sd7sK6/Ue4DgLRT+j9Iw0+8om09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P22087 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O95793 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NY61 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9UNX4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-727436|ensembl:ENSP00000308179 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:wdr3_human(display_long)|uniprotkb:WDR3(gene name)|psi-mi:WDR3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_006775.1|ensembl:ENSG00000065183(gene)|ensembl:ENST00000349139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:Q9UNX4|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:aslkTiEP+9ytaN6cc+SC+TzOxUg9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8TDN6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_060791.3|ensembl:ENSG00000113460(gene)|ensembl:ENST00000336767(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BVJ6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-473284|uniprotkb:B4DQ08|uniprotkb:E9PEL7|uniprotkb:Q5JYF1|uniprotkb:A8MVQ1|uniprotkb:A8K7A3|ensembl:ENSP00000377944 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ut14a_human(display_long)|uniprotkb:Serologically defined colon cancer antigen 16(gene name synonym)|uniprotkb:Antigen NY-CO-16(gene name synonym)|uniprotkb:UTP14A(gene name)|psi-mi:UTP14A(display_short)|uniprotkb:SDCCAG16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000156697(gene)|ensembl:ENST00000394422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0032040"(small-subunit processome)|interpro:IPR006709(Small-subunit processome, Utp14)|mint:Q9BVJ6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001159693.1|refseq:NP_006640.2|dip:DIP-32505N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:vBBHvYYgh4LYP335ktHlQ77Dkfc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8N8A6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-3893408|uniprotkb:A8MPT9|uniprotkb:Q96ED1|uniprotkb:Q5CZ71|uniprotkb:Q8IXK5|ensembl:ENSP00000380495|ensembl:ENSP00000500171 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx51_human(display_long)|uniprotkb:DDX51(gene name)|psi-mi:DDX51(display_short)|uniprotkb:DEAD box protein 51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_778236.2|ensembl:ENSG00000185163(gene)|ensembl:ENSG00000288503(gene)|ensembl:ENST00000397333(transcript)|ensembl:ENST00000673535(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q8N8A6 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:O3uYzRK+gCjUpzIu/5vxVMuBODc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NX24 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1050064|uniprotkb:Q9P095|uniprotkb:A6NKY8|intact:EBI-5774108|ensembl:ENSP00000274606 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nhp2_human(display_long)|uniprotkb:Nucleolar protein family A member 2(gene name synonym)|uniprotkb:snoRNP protein NHP2(gene name synonym)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:NOLA2(gene name synonym)|uniprotkb:HSPC286(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_060308.1|refseq:NP_001030005.1|ensembl:ENSG00000145912(gene)|ensembl:ENST00000274606(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:Q9NX24|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:ZZchZSzrw15BqMfddUMcaxZRF0w9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BQ39 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O43159 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2008793|uniprotkb:Q7KZ78|uniprotkb:Q9BVM6|ensembl:ENSP00000254605 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rrp8_human(display_long)|uniprotkb:RRP8(gene name)|psi-mi:RRP8(display_short)|uniprotkb:hucep-1(orf name)|uniprotkb:NML(gene name synonym)|uniprotkb:Nucleomethylin(gene name synonym)|uniprotkb:KIAA0409(gene name synonym)|uniprotkb:Cerebral protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056139.1|dip:DIP-46686N|ensembl:ENSG00000132275(gene)|ensembl:ENST00000254605(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046015"(regulation of transcription by glucose)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR007823(Methyltransferase-related)|interpro:IPR023576|interpro:IPR029063|interpro:IPR042036|mint:O43159|rcsb pdb:2ZFU|reactome:R-HSA-427359 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:SNRPocKaPjMCXSLDe1ytWlUWYTw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q7Z7K6 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1210604|uniprotkb:Q3L8N5|uniprotkb:Q8NFH6|uniprotkb:B2RPK2 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:cenpv_human(display_long)|uniprotkb:CENPV(gene name)|psi-mi:CENPV(display_short)|uniprotkb:Nuclear protein p30(gene name synonym)|uniprotkb:PRR6(gene name synonym)|uniprotkb:Proline-rich protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_859067.2|interpro:IPR006913(Glutathione-dependent formaldehyde-activating, GFA)|interpro:IPR011057(Mss4-like)|mint:Q7Z7K6|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0030496"(midbody)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0005829"(cytosol) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:q2Dt9PEcUigyqjqFMVm3dxk54B09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P42696 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2954772|ensembl:ENSP00000386226|uniprotkb:Q8N2Z8|uniprotkb:Q9H5A1|uniprotkb:A8K8J7 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rbm34_human(display_long)|uniprotkb:RBM34(gene name)|psi-mi:RBM34(display_short)|uniprotkb:KIAA0117(gene name synonym)|uniprotkb:RNA-binding motif protein 34(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000188739(gene)|ensembl:ENST00000408888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR034220|interpro:IPR034221|interpro:IPR035979|mint:P42696|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|refseq:NP_055829.2|refseq:NP_001333667.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:YrlnOTpyzg9F+4ZaZpLMfq4T4ts9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q14257 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q5JTH9 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-310743|uniprotkb:Q5JTH8|uniprotkb:Q69YK4|uniprotkb:Q96E87|uniprotkb:Q9BUH3|uniprotkb:Q9Y4C7|intact:EBI-2558452|uniprotkb:B4DK00|uniprotkb:E9PCK7|intact:EBI-28986119|ensembl:ENSP00000360031|ensembl:ENSP00000446184 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rrp12_human(display_long)|uniprotkb:RRP12(gene name)|psi-mi:RRP12(display_short)|uniprotkb:KIAA0690(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001138586.1|refseq:NP_055994.2|refseq:NP_001271266.1|ensembl:ENST00000315563|ensembl:ENSP00000324315|ensembl:ENSP00000360031|ensembl:ENST00000414986|ensembl:ENSP00000414863|ensembl:ENSP00000446184|ensembl:ENSG00000052749(gene)|ensembl:ENST00000370992(transcript)|ensembl:ENST00000536831(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012978(Region of unknown function, NUC173)|interpro:IPR016024(Armadillo-type fold)|mint:Q5JTH9 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:O2Ih3mwXBDMynmqc4UzvizKVnNg9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NUD5 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2954851|uniprotkb:Q3B7J3|ensembl:ENSP00000484056|uniprotkb:Q6NT79 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:zchc3_human(display_long)|uniprotkb:ZCCHC3(gene name)|psi-mi:ZCCHC3(display_short)|uniprotkb:C20orf99(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000247315(gene)|ensembl:ENST00000500893(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR042509|refseq:NP_149080.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:7OjndwgSqExNYquAbdZ2zX2Ploc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q12788 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-715766|uniprotkb:Q59GD6|uniprotkb:Q8IVB7|intact:EBI-749106|uniprotkb:Q96A78|ensembl:ENSP00000454836 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:tbl3_human(display_long)|uniprotkb:WD repeat-containing protein SAZD(gene name synonym)|uniprotkb:TBL3(gene name)|psi-mi:TBL3(display_short)|uniprotkb:SAZD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_006444.2|ensembl:ENSG00000183751(gene)|ensembl:ENST00000568546(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013934(Small-subunit processome, Utp13)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q12788|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:XFWYZxef3kNBYeTaoSBWEXQoF/M9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q7Z2W4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9GZL7 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2490660|uniprotkb:B3KPA9|uniprotkb:Q96HU0|uniprotkb:Q9NV80|uniprotkb:Q9NYI8|ensembl:ENSP00000261015 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:wdr12_human(display_long)|uniprotkb:WDR12(gene name)|psi-mi:WDR12(display_short)|uniprotkb:WD repeat-containing protein 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG go:"GO:0007219"(Notch signaling pathway)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR012972(NLE)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR028599|interpro:IPR036322|mint:Q9GZL7|rcsb pdb:6N31|rcsb pdb:6P0Q|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000138442(gene)|ensembl:ENST00000261015(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|refseq:NP_060726.3 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:7qCdIJOJA36eRlrwJA6x0XC/Tqc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BYG3 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2561019|ensembl:ENSP00000285814|uniprotkb:Q8TB66|uniprotkb:A8K788|uniprotkb:Q96ED4 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:mk67i_human(display_long)|uniprotkb:NIFK(gene name)|psi-mi:NIFK(display_short)|uniprotkb:MKI67IP(gene name synonym)|uniprotkb:NOPP34(gene name synonym)|uniprotkb:Nucleolar phosphoprotein Nopp34(gene name synonym)|uniprotkb:Nucleolar protein interacting with the FHA domain of pKI-67(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016072"(rRNA metabolic process)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021043|interpro:IPR035979|mint:Q9BYG3|rcsb pdb:2AFF|ensembl:ENSG00000155438(gene)|ensembl:ENST00000285814(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome)|refseq:NP_115766.3|dip:DIP-28134N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:DUc8AnzFxJjbK+cTW5H83GQcf6o9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NY12 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2510382|ensembl:ENSP00000226796|ensembl:ENSP00000378127|uniprotkb:Q5MJQ2 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:gar1_human(display_long)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:NOLA1(gene name synonym)|uniprotkb:snoRNP protein GAR1(gene name synonym)|uniprotkb:Nucleolar protein family A member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000109534(gene)|ensembl:ENST00000226796(transcript)|ensembl:ENST00000394631(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|mint:Q9NY12|rcsb pdb:7BGB|reactome:R-HSA-171319|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|reactome:R-HSA-6790901|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|refseq:NP_061856.1|refseq:NP_127460.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:voLJvYfWyMWtTf0VSd7XeY3psC09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P63244 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q99575 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NR30 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q13868 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NXF1 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2371062|uniprotkb:Q5T722|uniprotkb:Q5T723|uniprotkb:Q8NCN8|uniprotkb:Q8TDY0|uniprotkb:B4DYV2|ensembl:ENSP00000364037 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:tex10_human(display_long)|uniprotkb:TEX10(gene name)|psi-mi:TEX10(display_short)|uniprotkb:L18(orf name)|uniprotkb:Nbla10363(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_060216.2|refseq:NP_001155056.1|ensembl:ENSG00000136891(gene)|ensembl:ENST00000374902(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0071339"(MLL1 complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024679|interpro:IPR037947|mint:Q9NXF1|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:cQcRo1eExRkr/an7wvBN8Ttyatc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H7B2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1051960|uniprotkb:Q8N4A1|uniprotkb:Q5VXN1|ensembl:ENSP00000402338 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rpf2_human(display_long)|uniprotkb:RPF2(gene name)|psi-mi:RPF2(display_short)|uniprotkb:BXDC1(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:Brix domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_115570.1|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007109(Brix)|interpro:IPR039770|mint:Q9H7B2|ensembl:ENSG00000197498(gene)|ensembl:ENST00000441448(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:CXU4CHQmcrISLS8GDIwEMGhiaQI9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y3B9 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1055610|intact:EBI-28979625|ensembl:ENSP00000355899 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rrp15_human(display_long)|uniprotkb:Ribosomal RNA-processing protein 15(gene name synonym)|uniprotkb:RRP15(gene name)|psi-mi:RRP15(display_short)|uniprotkb:KIAA0507(gene name synonym)|uniprotkb:CGI-115(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSP00000355899|refseq:NP_057136.2|ensembl:ENSG00000067533(gene)|ensembl:ENST00000366932(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR012459(Protein of unknown function DUF1665) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:EJQFG76HKEYeJ6LwFd5zaUmoScw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H8H2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-395655|uniprotkb:Q5K6N2|uniprotkb:Q5K6N3|uniprotkb:Q5K6N4|uniprotkb:Q5VZJ4|uniprotkb:Q5VZJ9|uniprotkb:Q96E91|uniprotkb:Q96NY2|uniprotkb:Q96SX5|uniprotkb:Q9H5K6|ensembl:ENSP00000361226|ensembl:ENSP00000361232 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx31_human(display_long)|uniprotkb:DEAD box protein 31(gene name synonym)|uniprotkb:Helicain(gene name synonym)|uniprotkb:DDX31(gene name)|psi-mi:DDX31(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_073616.6|refseq:NP_619526.1|ensembl:ENSG00000125485(gene)|ensembl:ENST00000372153(transcript)|ensembl:ENST00000372159(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_001309269.1|refseq:NP_001309273.1|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|mint:Q9H8H2|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:HaC4SAnIvujAJVEcn/88Wij/zTM9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q92900 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q92615 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055970.1|ensembl:ENSP00000326128|ensembl:ENSG00000107929(gene)|ensembl:ENST00000316157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3PTH - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q6PK04 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-714654|ensembl:ENSP00000329360|ensembl:ENSP00000458884 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:cc137_human(display_long)|uniprotkb:CCDC137(gene name)|psi-mi:CCDC137(display_short)|uniprotkb:cPERP-B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_954981.1|ensembl:ENSG00000185298(gene)|ensembl:ENST00000329214(transcript)|ensembl:ENST00000575223(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR026680|mint:Q6PK04 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:e64Y/4oJpFqmYZEO1lOUHeLwy0I9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q99700 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-697691|uniprotkb:Q6ZQZ7|uniprotkb:Q99493|uniprotkb:A6NLD4|uniprotkb:Q24JQ7|ensembl:ENSP00000446576 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:atx2_human(display_long)|uniprotkb:Spinocerebellar ataxia type 2 protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 13 protein(gene name synonym)|uniprotkb:SCA2(gene name synonym)|uniprotkb:TNRC13(gene name synonym)|uniprotkb:ATXN2(gene name)|psi-mi:ATXN2(display_short)|uniprotkb:ATX2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_002964.3|refseq:NP_001297052.1|ensembl:ENSG00000204842(gene)|ensembl:ENST00000550104(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR025852|interpro:IPR033093|mint:Q99700|rcsb pdb:3KTR|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000535949|ensembl:ENSP00000439338|ensembl:ENSP00000446576|ensembl:ENST00000616825|ensembl:ENSP00000481448|dip:DIP-33372N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:HGRv/9J/X3JIj2KmcHviwd2ygPw9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O60832 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-713091|ensembl:ENSP00000358563|uniprotkb:O43845|uniprotkb:Q96G67|uniprotkb:Q9Y505|uniprotkb:F5BSB3 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:dkc1_human(display_long)|uniprotkb:Dyskerin(gene name synonym)|uniprotkb:Nucleolar protein family A member 4(gene name synonym)|uniprotkb:snoRNP protein DKC1(gene name synonym)|uniprotkb:Nopp140-associated protein of 57 kDa(gene name synonym)|uniprotkb:Nucleolar protein NAP57(gene name synonym)|uniprotkb:CBF5 homolog(gene name synonym)|uniprotkb:DKC1(gene name)|psi-mi:DKC1(display_short)|uniprotkb:NOLA4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|mint:O60832|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901|interpro:IPR002478(PUA)|ensembl:ENSG00000130826(gene)|ensembl:ENST00000369550(transcript)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003720"(telomerase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990481"(mRNA pseudouridine synthesis)|go:"GO:0006396"(RNA processing)|refseq:NP_001354.1|refseq:NP_001135935.1|refseq:NP_001275676.1|dip:DIP-40645N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:njIdhtX9m37BslwxyAAV/JoRrHo9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y2X3 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NZM5 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_056525.2|ensembl:ENSG00000105373(gene)|ensembl:ENST00000246802(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0003723"(RNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990173"(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|go:"GO:0050821"(protein stabilization) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q01780 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q99848 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q49A26 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2804292|ensembl:ENSP00000322716|uniprotkb:Q6P1Q2|uniprotkb:C9JJ40|uniprotkb:Q9BTI1|uniprotkb:Q9BXK2|uniprotkb:Q6V3W7|uniprotkb:C9JJ60|uniprotkb:B4DL47|uniprotkb:Q5U632 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:glyr1_human(display_long)|uniprotkb:HIBDL(gene name synonym)|uniprotkb:NP60(gene name synonym)|uniprotkb:3-hydroxyisobutyrate dehydrogenase-like protein(gene name synonym)|uniprotkb:Cytokine-like nuclear factor N-PAC(gene name synonym)|uniprotkb:Glyoxylate reductase 1 homolog(gene name synonym)|uniprotkb:Nuclear protein NP60(gene name synonym)|uniprotkb:Nuclear protein of 60 kDa(gene name synonym)|uniprotkb:GLYR1(gene name)|psi-mi:GLYR1(display_short)|uniprotkb:NDF(gene name synonym)|uniprotkb:Nucleosome-destabilizing factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000140632(gene)|ensembl:ENST00000321919(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR000313(PWWP)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR029154|interpro:IPR035501|interpro:IPR036291|mint:Q49A26|rcsb pdb:2UYY|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GUT|rcsb pdb:4GUU|rcsb pdb:4HSU|rcsb pdb:6R1U|rcsb pdb:6R25|refseq:XP_011521019.1|refseq:NP_001295025.1|refseq:NP_115958.2|refseq:NP_001311026.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:QsJhkB7Klk8D2R03vqPZzbi3f9g9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P26196 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9Y3C1 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BVP2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENST00000394799|ensembl:ENSP00000378278|ensembl:ENSP00000395772|refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938(gene)|ensembl:ENST00000418458(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030496"(midbody)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|mint:Q9BVP2|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8N9T8 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-724923|uniprotkb:Q2M1R5|uniprotkb:Q2M1R7|uniprotkb:Q7L5J7|uniprotkb:Q96G92|uniprotkb:Q9BU50|uniprotkb:Q9H6I1|uniprotkb:Q9H978|ensembl:ENSP00000320917 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:kri1_human(display_long)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_075384.3|ensembl:ENSG00000129347(gene)|ensembl:ENST00000312962(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|mint:Q8N9T8 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:sIRmrP/c3tSmEAj1usRGN3R3Bh09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H6W3 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9H0A0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9NVP1 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-724378|ensembl:ENSP00000263239|uniprotkb:Q6GTZ9|uniprotkb:Q6IAU4|uniprotkb:Q92732|uniprotkb:Q9BQB7 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ddx18_human(display_long)|uniprotkb:DEAD box protein 18(gene name synonym)|uniprotkb:Myc-regulated DEAD box protein(gene name synonym)|uniprotkb:DDX18(gene name)|psi-mi:DDX18(display_short)|uniprotkb:cPERP-D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_006764.3|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025313|interpro:IPR027417|interpro:IPR044773|mint:Q9NVP1|rcsb pdb:3LY5|ensembl:ENSG00000088205(gene)|ensembl:ENST00000263239(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0071392"(cellular response to estradiol stimulus) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:RmupZbt33/w1V7Uq5vnRO36j2Tc9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O60287 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1762349|uniprotkb:D3DSE5|uniprotkb:Q96NX1|uniprotkb:Q9NYQ1|ensembl:ENSP00000372199 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:npa1p_human(display_long)|uniprotkb:URB1(gene name)|psi-mi:URB1(display_short)|uniprotkb:C21orf108(gene name synonym)|uniprotkb:KIAA0539(gene name synonym)|uniprotkb:NPA1(gene name synonym)|uniprotkb:URB1 ribosome biogenesis 1 homolog(gene name synonym)|uniprotkb:NOP254(gene name synonym)|uniprotkb:Nucleolar protein 254 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_055640.2|interpro:IPR021714|interpro:IPR032436|interpro:IPR039844|ensembl:ENSG00000142207(gene)|ensembl:ENST00000382751(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR016024(Armadillo-type fold) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:tolq2rVG0N5qy3qGiIkPj8xtVis9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:P78346 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-366553|uniprotkb:B2R799|uniprotkb:E9PB02|ensembl:ENSP00000360768 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rpp30_human(display_long)|uniprotkb:RPP30(gene name)|psi-mi:RPP30(display_short)|uniprotkb:RNASEP2(gene name synonym)|uniprotkb:RNase P subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001098016.1|refseq:NP_006404.1|refseq:XP_011537422.1|refseq:XP_011537423.1|ensembl:ENSG00000148688(gene)|ensembl:ENST00000371703(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P78346|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016870964.1|refseq:XP_016870966.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:pRHvUnpzpNHGzYbS+kRiSa0m71E9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q76FK4 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-396069|uniprotkb:Q5TCC7|uniprotkb:Q5TCC8|uniprotkb:Q5TCD3|uniprotkb:Q5TCD5|uniprotkb:Q5TCD6|uniprotkb:Q5TCD7|uniprotkb:Q76D35|uniprotkb:Q7L3E2|uniprotkb:Q9H586|uniprotkb:Q9H795|uniprotkb:Q9H7W7|uniprotkb:Q9H9J6|uniprotkb:Q9NWA4|uniprotkb:Q9NWM4|ensembl:ENSP00000401177|ensembl:ENSP00000441140 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nol8_human(display_long)|uniprotkb:Nucleolar protein Nop132(gene name synonym)|uniprotkb:NOL8(gene name)|psi-mi:NOL8(display_short)|uniprotkb:C9orf34(gene name synonym)|uniprotkb:NOP132(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_060418.4|refseq:XP_011517126.1|ensembl:ENSG00000198000(gene)|ensembl:ENST00000442668(transcript)|ensembl:ENST00000545558(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034138|interpro:IPR035979|refseq:NP_001243323.1|refseq:XP_006717229.1|refseq:XP_006717230.1|refseq:XP_006717232.1|refseq:XP_006717233.1|refseq:NP_001317651.1|refseq:XP_016870365.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:tKGGHXKwb9YuzARkLi19za57xZM9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q71RC2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2878091|ensembl:ENSP00000381490|uniprotkb:Q96NF9|uniprotkb:A8K6T1|uniprotkb:Q6ZV14|uniprotkb:Q5CZ97|uniprotkb:G5E976|uniprotkb:E9PDG5|uniprotkb:G3XAA8 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:larp4_human(display_long)|uniprotkb:LARP4(gene name)|psi-mi:LARP4(display_short)|uniprotkb:La ribonucleoprotein domain family member 4(gene name synonym)|uniprotkb:PP13296(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000161813(gene)|ensembl:ENST00000398473(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR034903|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2CQK|rcsb pdb:3PKN|rcsb pdb:6I9B|refseq:XP_011536140.1|refseq:NP_001164279.1|refseq:NP_443111.4|refseq:NP_954658.2|refseq:NP_001317344.1|refseq:XP_016874240.1|refseq:XP_016874242.1|refseq:XP_016874243.1|refseq:NP_954660.1|refseq:XP_005268670.1|refseq:XP_011536141.1|refseq:XP_011536142.1|refseq:XP_011536143.1|refseq:XP_016874241.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:9FwnSJmbM08zYGHJB3l61hB1lJk9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q6P158 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1051531|uniprotkb:Q53SI4|uniprotkb:Q6P9G1|uniprotkb:Q7Z6H3|uniprotkb:Q8NG17|uniprotkb:Q96M33|uniprotkb:A2RRC7|ensembl:ENSP00000405111 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:dhx57_human(display_long)|uniprotkb:DEAH box protein 57(gene name synonym)|uniprotkb:DHX57(gene name)|psi-mi:DHX57(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_945314.1|refseq:XP_011531456.1|refseq:XP_011531457.1|ensembl:ENSG00000163214(gene)|ensembl:ENST00000457308(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006575(RWD)|interpro:IPR007502(Helicase-associated region)|interpro:IPR009060(UBA-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR027417|interpro:IPR036855|interpro:IPR041367|interpro:IPR042615|mint:Q6P158 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:+srrYp6+3YKAvSOr8wkq0Vcjsvo9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q03701 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O00567 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q7Z2T5 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1237316|uniprotkb:Q5TEN0|uniprotkb:Q6ZMX0|uniprotkb:Q8IWH5|uniprotkb:Q8NC68|uniprotkb:Q9BZQ1|ensembl:ENSP00000356476 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:trm1l_human(display_long)|uniprotkb:TRMT1L(gene name)|psi-mi:TRMT1L(display_short)|uniprotkb:C1orf25(gene name synonym)|uniprotkb:MSTP070(orf name)|uniprotkb:TRM1L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001189352.1|refseq:NP_112196.3|ensembl:ENSG00000121486(gene)|ensembl:ENST00000367506(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002940"(tRNA N2-guanine methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0004809"("tRNA (guanine-N2-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0007610"(behavior)|go:"GO:0046872"(metal ion binding)|interpro:IPR002905(N2,N2-dimethylguanosine tRNA methyltransferase)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029063|interpro:IPR042296 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:dctCUlcYZCnaX72mW3b0n9JM5w89606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9GZR2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2856313|uniprotkb:Q5T8S4|uniprotkb:B2RAT2|uniprotkb:Q9GZW3|uniprotkb:Q5T8S6|uniprotkb:Q5T8S5|ensembl:ENSP00000361010|ensembl:ENSP00000486065 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rexo4_human(display_long)|uniprotkb:REXO4(gene name)|psi-mi:REXO4(display_short)|uniprotkb:PMC2(gene name synonym)|uniprotkb:XPMC2H(gene name synonym)|uniprotkb:Exonuclease XPMC2(gene name synonym)|uniprotkb:Prevents mitotic catastrophe 2 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001266278.1|refseq:NP_001266279.1|refseq:NP_001266280.1|refseq:NP_065118.2|ensembl:ENSG00000148300(gene)|ensembl:ENSG00000280706(gene)|ensembl:ENST00000371942(transcript)|ensembl:ENST00000630460(transcript)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034920|interpro:IPR036397|interpro:IPR037431|mint:Q9GZR2|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold) - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:N0OxZ2by59SnW1Xup2iaA29RPCU9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q13601 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9BQG0 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q9UKD2 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-1046493|ensembl:ENSP00000364320|uniprotkb:Q9BPV9|uniprotkb:Q5TG55|uniprotkb:Q96SS6|uniprotkb:B3KNB3 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:mrt4_human(display_long)|uniprotkb:MRTO4(gene name)|psi-mi:MRTO4(display_short)|uniprotkb:C1orf33(gene name synonym)|uniprotkb:MRT4(gene name synonym)|uniprotkb:Ribosome assembly factor MRTO4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000053372(gene)|ensembl:ENST00000330263(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:Q9UKD2|interpro:IPR033867|refseq:NP_057267.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:LpvX3By1Cp6MxlAx3d5qoDM3FNY9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:O15226 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-766011|uniprotkb:Q4VC41|uniprotkb:Q9UJ91|uniprotkb:G3V1N1|ensembl:ENSP00000304803 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:nkrf_human(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Protein ITBA4(gene name synonym)|uniprotkb:NKRF(gene name)|psi-mi:NKRF(display_short)|uniprotkb:ITBA4(gene name synonym)|uniprotkb:NRF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG refseq:NP_001166958.1|refseq:NP_001166959.1|refseq:NP_060014.2|refseq:XP_011529667.1|dip:DIP-34570N|ensembl:ENSG00000186416(gene)|ensembl:ENST00000304449(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036867|mint:O15226|rcsb pdb:6SH6|rcsb pdb:6SH7|interpro:IPR034071 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:jH7qlOvuAHKsjuOyzDpBonpgtF09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8IZL8 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:iu03DsintVoo3gWzZX14SlHE0ao9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q5T280 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2880213|ensembl:ENSP00000354812|uniprotkb:Q6PIJ1|uniprotkb:Q6PJV9|uniprotkb:Q6P469|uniprotkb:Q6PGP9|uniprotkb:Q0D2P6 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:ci114_human(display_long)|uniprotkb:SPOUT1(gene name)|psi-mi:SPOUT1(display_short)|uniprotkb:C9orf114(gene name synonym)|uniprotkb:Centromere protein 32(gene name synonym)|uniprotkb:Kinetochore-associated protein(gene name synonym)|uniprotkb:SPOUT domain-containing methyltransferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000198917(gene)|ensembl:ENST00000361256(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032259"(methylation)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0072686"(mitotic spindle)|interpro:IPR003750(Protein of unknown function DUF171)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:4RG1|refseq:NP_057474.2 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:xsCr/8Iqdx4wJ6XweqC73CSia749606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8NI36 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-2512413|ensembl:ENSP00000423067|ensembl:ENSP00000479950|uniprotkb:A2RUS4|uniprotkb:Q8N1Q2|uniprotkb:Q68E02 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:wdr36_human(display_long)|uniprotkb:WDR36(gene name)|psi-mi:WDR36(display_short)|uniprotkb:T-cell activation WD repeat-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000134987(gene)|ensembl:ENST00000506538(transcript)|ensembl:ENST00000612402(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0007601"(visual perception)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|go:"GO:0050896"(response to stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR007319(Small-subunit processome, Utp21)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|refseq:NP_644810.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:97Qc0ehUPTjCBcn3gjr0FY8Nnus9606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q8WWM7 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41218 uniprotkb:Q14690 intact:EBI-2829677|ensembl:ENSP00000357123 intact:EBI-300028|uniprotkb:Q9H4P1|ensembl:ENSP00000358812|uniprotkb:Q86VQ8|uniprotkb:Q5W093|uniprotkb:Q2TA92|uniprotkb:Q6P2J3 psi-mi:mnda_human(display_long)|uniprotkb:MNDA(gene name)|psi-mi:MNDA(display_short) psi-mi:rrp5_human(display_long)|uniprotkb:PDCD11(gene name)|psi-mi:PDCD11(display_short)|uniprotkb:KIAA0185(gene name synonym)|uniprotkb:Programmed cell death protein 11(gene name synonym)|uniprotkb:NF-kappa-B-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9996028|imex:IM-23523-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002423.1|ensembl:ENSG00000163563(gene)|ensembl:ENST00000368141(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006968"(cellular defense response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205|mint:P41218|rcsb pdb:5H7Q|rcsb pdb:5WPZ|reactome:R-HSA-6798695|rcsb pdb:2DBG ensembl:ENSG00000148843(gene)|ensembl:ENST00000369797(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008134"(transcription factor binding)|go:"GO:0032040"(small-subunit processome)|interpro:IPR003029(S1, RNA binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008847(Suppressor of forked)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|mint:Q14690|rcsb pdb:1WI5|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0006397"(mRNA processing)|refseq:NP_055791.1|refseq:XP_011537841.1 - - - figure legend:Supp. Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2019/01/23 rogid:KYAX5onmaTu+MLjhSNnAgtTPgd49606 rogid:G3h7KMQzbRdyetWmb3uVBqXJWu09606 intact-crc:2E2D6383AB3328D5|rigid:tllFZlzr9ahF3Ehg6qswVoZIHbA false green fluorescent protein tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6K0P9 intact:EBI-10706085 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 - psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:isd(display_short)|psi-mi:EBI-10706085(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:169963(lismo)|taxid:169963("Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-10706081|imex:IM-23523-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 - - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/04 2022/02/01 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 - - false sufficient binding region:200-492|glutathione s tranferase tag:?-? biotin tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q6K0P9 intact:EBI-10706085 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 - psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:isd(display_short)|psi-mi:EBI-10706085(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:169963(lismo)|taxid:169963("Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10706106|imex:IM-23523-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 - - - - figure legend:Fig. 6A, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/04 2022/02/01 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 - - false sufficient binding region:200-492|glutathione s tranferase tag:?-? biotin tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q6K0P9 intact:EBI-10706085 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 - psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:isd(display_short)|psi-mi:EBI-10706085(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:169963(lismo)|taxid:169963("Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10706106|imex:IM-23523-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0681"(double stranded deoxyribonucleic acid) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 - - - - figure legend:Fig. 6A, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/12/04 2022/02/01 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 - - false sufficient binding region:200-492|glutathione s tranferase tag:?-? - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q6K0P9 intact:EBI-10706140 intact:EBI-9545390|uniprotkb:Q5T3W6|uniprotkb:Q6K0P6|uniprotkb:Q6K0P7|uniprotkb:Q6K0P8|uniprotkb:Q8WW65|ensembl:ENSP00000357122 - psi-mi:ifix_human(display_long)|uniprotkb:PYHIN1(gene name)|psi-mi:PYHIN1(display_short)|uniprotkb:IFIX(gene name synonym)|uniprotkb:Interferon-inducible protein X(gene name synonym) psi-mi:vacv70(display_short)|psi-mi:EBI-10706140(display_long) psi-mi:"MI:0416"(fluorescence microscopy) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10706125|imex:IM-23523-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0318"(nucleic acid) refseq:XP_011507544.1|refseq:NP_689714.2|refseq:NP_945146.1|refseq:NP_945147.1|refseq:NP_945148.1|refseq:XP_005244987.1|ensembl:ENSG00000163564(gene)|ensembl:ENST00000368140(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR004020(Pyrin)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR011029(DEATH-like)|interpro:IPR040205 - go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 6D, Supp. Fig. 10A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2015/03/18 rogid:zUoeXvsnuXvT1wKPV7Z22qF1NLY9606 - - false green fluorescent protein tag:?-? cy3 label:?-? - - psi-mi:"MI:1198"(immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry) uniprotkb:Q16666-2 intact:EBI-10706140 intact:EBI-6273540|ensembl:ENSP00000357113|ensembl:ENSP00000357114 - psi-mi:q16666-2(display_long)|uniprotkb:IFI 16B(isoform synonym)|uniprotkb:IFI16(gene name)|psi-mi:IFI16(display_short)|uniprotkb:IFNGIP1(gene name synonym)|uniprotkb:Interferon-inducible myeloid differentiation transcriptional activator(gene name synonym) psi-mi:vacv70(display_short)|psi-mi:EBI-10706140(display_long) psi-mi:"MI:0416"(fluorescence microscopy) Diner et al. (2015) imex:IM-23523|pubmed:25665578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-10706146|imex:IM-23523-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0318"(nucleic acid) intact:EBI-2867186(isoform-parent)|ensembl:ENSG00000163565(gene)|ensembl:ENST00000368131(transcript)|ensembl:ENST00000368132(transcript) - go:"GO:0005737"(cytoplasm) isoform-comment:Major isoform. - figure legend:Supp. Fig. 10B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/12/04 2015/03/18 rogid:uKNPD5KtHA2BHm1V/wqoNDKDOtQ9606 - - false green fluorescent protein tag:?-? cy3 label:?-? - - psi-mi:"MI:1198"(immunohistochemistry) psi-mi:"MI:1198"(immunohistochemistry)