#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O95863 uniprotkb:Q86XK2 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9869654|imex:IM-23299-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 - - - figure legend:7E|antagonist:"knockdown of \"PKD1\" -Protein Kinase D1."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf10a)|taxid:9606(Human non-transformed breast epithelial cell line) - 2014/10/22 2014/11/19 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 intact-crc:99E65A30B96FC6EE|rigid:bK33mgWeiaoCamHfPjkvgpk5kwc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95863 uniprotkb:O14543 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 intact:EBI-714146|uniprotkb:O14509|ensembl:ENSP00000330341 psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:socs3_human(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:STAT-induced STAT inhibitor 3(gene name synonym)|uniprotkb:SOCS3(gene name)|psi-mi:SOCS3(display_short)|uniprotkb:CIS3(gene name synonym)|uniprotkb:SSI3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980274|imex:IM-23299-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O14543|reactome:R-HSA-1059683|reactome:R-HSA-2586552|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8849474|reactome:R-HSA-8939242|reactome:R-HSA-8951664|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983168|go:"GO:0050728"(negative regulation of inflammatory response)|ensembl:ENSG00000184557(gene)|ensembl:ENST00000330871(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|refseq:NP_003946.3 - - - figure legend:1Hii|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2015/07/21 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rogid:8HnU9EL52BGdud2WFZwYsv5R22I9606 intact-crc:888C9414C34A7D00|rigid:pwJBN6TuqxRzhITq5MUG+1Q1sis false flag tag:?-? ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95863 uniprotkb:Q96BD6 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 intact:EBI-2659201|uniprotkb:Q9BRY9|uniprotkb:Q59FA1|uniprotkb:Q5TIH9|uniprotkb:A2A275|uniprotkb:Q9H6C5|intact:EBI-28985495|ensembl:ENSP00000330221|ensembl:ENSP00000350573|ensembl:ENSP00000366616 psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:spsb1_human(display_long)|uniprotkb:SSB1(gene name synonym)|uniprotkb:SPSB1(gene name)|psi-mi:SPSB1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980283|imex:IM-23299-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N refseq:NP_079382.2|ensembl:ENSP00000330221|ensembl:ENSP00000350573|ensembl:ENSP00000366616|ensembl:ENSG00000171621(gene)|ensembl:ENST00000328089(transcript)|ensembl:ENST00000357898(transcript)|ensembl:ENST00000377399(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q96BD6|rcsb pdb:2JK9|rcsb pdb:3F2O|reactome:R-HSA-8951664|reactome:R-HSA-983168 - - - figure legend:1HIiii|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2015/07/21 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rogid:oILuoZD3/R7RwvYVRHWDTXMHctE9606 intact-crc:D44F0A484B71C79C|rigid:cUtbecHBPlT/Tpo2dMhYQSCe5Mw false flag tag:?-? ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XK2 uniprotkb:O95863 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980266|imex:IM-23299-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:1Hi|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2014/11/19 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:4017831CFF617039|rigid:bK33mgWeiaoCamHfPjkvgpk5kwc false ha tag:n-n flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XK2 uniprotkb:O95863 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980204|imex:IM-23299-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:1Ii, 6C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2014/11/19 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:1AA9462E14152165|rigid:bK33mgWeiaoCamHfPjkvgpk5kwc false ha tag:n-n flag tag:?-?|necessary binding region:1-20 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95863 uniprotkb:O14543 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 intact:EBI-714146|uniprotkb:O14509|ensembl:ENSP00000330341 psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:socs3_human(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:STAT-induced STAT inhibitor 3(gene name synonym)|uniprotkb:SOCS3(gene name)|psi-mi:SOCS3(display_short)|uniprotkb:CIS3(gene name synonym)|uniprotkb:SSI3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980221|imex:IM-23299-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O14543|reactome:R-HSA-1059683|reactome:R-HSA-2586552|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8849474|reactome:R-HSA-8939242|reactome:R-HSA-8951664|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983168|go:"GO:0050728"(negative regulation of inflammatory response)|ensembl:ENSG00000184557(gene)|ensembl:ENST00000330871(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|refseq:NP_003946.3 - - - figure legend:1Iii|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2015/07/21 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rogid:8HnU9EL52BGdud2WFZwYsv5R22I9606 intact-crc:6C6C04B6DFCF4A72|rigid:pwJBN6TuqxRzhITq5MUG+1Q1sis false flag tag:?-? ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95863 uniprotkb:Q9C035 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420 psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980242|imex:IM-23299-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300 - - - figure legend:1Iiv|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2015/07/21 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606 intact-crc:9B621404D383F88A|rigid:uy5MFEfH/2PRJd3O/3+k5aQ0iBg false flag tag:?-? ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96BD6 uniprotkb:O95863 intact:EBI-2659201|uniprotkb:Q9BRY9|uniprotkb:Q59FA1|uniprotkb:Q5TIH9|uniprotkb:A2A275|uniprotkb:Q9H6C5|intact:EBI-28985495|ensembl:ENSP00000330221|ensembl:ENSP00000350573|ensembl:ENSP00000366616 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:spsb1_human(display_long)|uniprotkb:SSB1(gene name synonym)|uniprotkb:SPSB1(gene name)|psi-mi:SPSB1(display_short) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980232|imex:IM-23299-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079382.2|ensembl:ENSP00000330221|ensembl:ENSP00000350573|ensembl:ENSP00000366616|ensembl:ENSG00000171621(gene)|ensembl:ENST00000328089(transcript)|ensembl:ENST00000357898(transcript)|ensembl:ENST00000377399(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q96BD6|rcsb pdb:2JK9|rcsb pdb:3F2O|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:1Iiii|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2015/07/21 rogid:oILuoZD3/R7RwvYVRHWDTXMHctE9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:F0A6376885781575|rigid:cUtbecHBPlT/Tpo2dMhYQSCe5Mw false ha tag:n-n flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9C035 uniprotkb:O95863 intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980257|imex:IM-23299-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:1Hiv|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2015/07/21 rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:E25F34CB116111B5|rigid:uy5MFEfH/2PRJd3O/3+k5aQ0iBg false ha tag:n-n flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N1E6 uniprotkb:O95863 intact:EBI-6425532|ensembl:ENSP00000344855 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:fxl14_human(display_long)|uniprotkb:FBXL14(gene name)|psi-mi:FBXL14(display_short)|uniprotkb:F-box and leucine-rich repeat protein 14(gene name synonym)|uniprotkb:FBL14(gene name synonym) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-10952763|imex:IM-23299-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171823(gene)|ensembl:ENST00000339235(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR036047|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_689654.1 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:Supp 2K|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2015/08/03 rogid:H8Gc4/0VTyLxX8UBNy6g0k5m1Qk9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rigid:wApSiYCI0jQONQHrXFy3N0Zes0A false v5 tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86XK2 uniprotkb:O95863 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9869641|imex:IM-23299-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:2B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma) - 2014/10/22 2015/08/06 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:BB4624EFEEBAD229|rigid:bK33mgWeiaoCamHfPjkvgpk5kwc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:O95863 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980334|imex:IM-23299-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:Supp 1J, 6A|antagonist:"alkaline phosphatase (calf intestinal phosphatase [CIP])"|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2014/11/19 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:5692F6098968BD4D|rigid:bK33mgWeiaoCamHfPjkvgpk5kwc false ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95863 uniprotkb:O14543 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 intact:EBI-714146|uniprotkb:O14509|ensembl:ENSP00000330341 psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:socs3_human(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:STAT-induced STAT inhibitor 3(gene name synonym)|uniprotkb:SOCS3(gene name)|psi-mi:SOCS3(display_short)|uniprotkb:CIS3(gene name synonym)|uniprotkb:SSI3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980340|imex:IM-23299-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O14543|reactome:R-HSA-1059683|reactome:R-HSA-2586552|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8849474|reactome:R-HSA-8939242|reactome:R-HSA-8951664|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-983168|go:"GO:0050728"(negative regulation of inflammatory response)|ensembl:ENSG00000184557(gene)|ensembl:ENST00000330871(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|refseq:NP_003946.3 - - - figure legend:Supp 1J|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2014/11/19 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rogid:8HnU9EL52BGdud2WFZwYsv5R22I9606 intact-crc:9067912F999A7CFE|rigid:pwJBN6TuqxRzhITq5MUG+1Q1sis false - ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86XK2 uniprotkb:O95863 intact:EBI-1047804|uniprotkb:Q9H9L1|uniprotkb:Q9NR14|uniprotkb:Q9UFK1|uniprotkb:Q52ZP1|uniprotkb:Q53EP7|uniprotkb:Q8IXG3|uniprotkb:Q96E90|uniprotkb:Q9H6V8|uniprotkb:Q9UHI1|uniprotkb:Q9UKC2|uniprotkb:Q53RT5|uniprotkb:A1L491|ensembl:ENSP00000384823 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:fbx11_human(display_long)|uniprotkb:Vitiligo-associated protein 1(gene name synonym)|uniprotkb:FBXO11(gene name)|psi-mi:FBXO11(display_short)|uniprotkb:FBX11(gene name synonym)|uniprotkb:VIT1(gene name synonym)|uniprotkb:PRMT9(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 9(gene name synonym)|uniprotkb:UG063H01(orf name) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980408|imex:IM-23299-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177203.1|refseq:XP_016860506.1|refseq:NP_079409.3|refseq:XP_005264629.1|dip:DIP-35680N|ensembl:ENSG00000138081(gene)|ensembl:ENST00000403359(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR006633(Carbohydrate-binding and sugar hydrolysis)|interpro:IPR007742(Periplasmic copper-binding)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR022441|interpro:IPR029799|interpro:IPR036047|interpro:IPR039448|rcsb pdb:5VMD|reactome:R-HSA-8951664|reactome:R-HSA-983168 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:6D, 7B, supp 6B/D|antagonist:"The PKD1 (protein kinase D1) inhibitor CID755673, as well as the dominant-negative PKD1-KW mutant, disrupted the interaction between SNAIL and FBXO11 protein."|comment:"Co-Ip experiments using several SNAIL mutants, (including the 6SA mutant, which can no longer be phosphorylated by GSK-3beta) did not disrupt the interaction between SNAIL and FBXO11 protein."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2014/11/19 rogid:7tSKElIYe8osUxG4NtKI0lWkLak9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:E555CE9A4A687B82|rigid:bK33mgWeiaoCamHfPjkvgpk5kwc false ha tag:n-n mutation disrupting interaction strength:6-6|mutation increasing interaction strength:11-11|mutation disrupting interaction strength:11-11|flag tag:?-?|mutation disrupting interaction strength:8-8|mutation disrupting interaction strength:11-11 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9C035 uniprotkb:O95863 intact:EBI-924214|uniprotkb:Q2MLV4|uniprotkb:Q2MLV8|uniprotkb:Q2MLV9|uniprotkb:Q2MLW1|uniprotkb:Q2MLW3|uniprotkb:Q2MLW4|uniprotkb:A6NGQ1|uniprotkb:Q2MLW6|uniprotkb:Q2MLW7|uniprotkb:Q2MLX1|uniprotkb:Q2MLX2|uniprotkb:Q2MLX3|uniprotkb:Q2MLX5|uniprotkb:Q2MLY3|uniprotkb:Q2MLY4|uniprotkb:Q2V6Q6|uniprotkb:Q6GX26|uniprotkb:Q8WU46|uniprotkb:Q96SR5|uniprotkb:Q9C031|uniprotkb:Q9C032|uniprotkb:Q9C033|uniprotkb:Q9C034|uniprotkb:A8WFA8|uniprotkb:D3DQS8|uniprotkb:D3DQS9|uniprotkb:G3GJY1|ensembl:ENSP00000369373|ensembl:ENSP00000507420 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:trim5_human(display_long)|uniprotkb:TRIM5(gene name)|psi-mi:TRIM5(display_short)|uniprotkb:RNF88(gene name synonym)|uniprotkb:RING finger protein 88(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM5(gene name synonym) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980330|imex:IM-23299-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149023.2|refseq:NP_149083.2|refseq:NP_149084.2|refseq:XP_011518729.1|refseq:XP_005253240.1|refseq:XP_005253241.1|ensembl:ENSG00000132256(gene)|ensembl:ENST00000380034(transcript)|ensembl:ENST00000684655(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031664"(regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR027370|interpro:IPR043136|rcsb pdb:2ECV|rcsb pdb:2YRG|reactome:R-HSA-877300 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:Supp 1J|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2014/11/19 rogid:t0YqhaJC8oQcwot7oks1LgMxdNc9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:4E76DAE9E08D3481|rigid:uy5MFEfH/2PRJd3O/3+k5aQ0iBg false ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8N1E6 uniprotkb:O95863 intact:EBI-6425532|ensembl:ENSP00000344855 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 psi-mi:fxl14_human(display_long)|uniprotkb:FBXL14(gene name)|psi-mi:FBXL14(display_short)|uniprotkb:F-box and leucine-rich repeat protein 14(gene name synonym)|uniprotkb:FBL14(gene name synonym) psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980632|imex:IM-23299-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171823(gene)|ensembl:ENST00000339235(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR036047|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_689654.1 refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N - - - figure legend:Supp 7G|antagonist:C3 Transferase -a RhoA inhibitor|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2014/11/19 rogid:H8Gc4/0VTyLxX8UBNy6g0k5m1Qk9606 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 intact-crc:1C729020D64A59CA|rigid:wApSiYCI0jQONQHrXFy3N0Zes0A false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95863 uniprotkb:Q96BD6 intact:EBI-1045459|uniprotkb:Q9P113|uniprotkb:Q9UBP7|uniprotkb:Q9UHH7|ensembl:ENSP00000244050|uniprotkb:B2R842 intact:EBI-2659201|uniprotkb:Q9BRY9|uniprotkb:Q59FA1|uniprotkb:Q5TIH9|uniprotkb:A2A275|uniprotkb:Q9H6C5|intact:EBI-28985495|ensembl:ENSP00000330221|ensembl:ENSP00000350573|ensembl:ENSP00000366616 psi-mi:snai1_human(display_long)|uniprotkb:Protein snail homolog 1(gene name synonym)|uniprotkb:SNAI1(gene name)|psi-mi:SNAI1(display_short)|uniprotkb:SNAH(gene name synonym) psi-mi:spsb1_human(display_long)|uniprotkb:SSB1(gene name synonym)|uniprotkb:SPSB1(gene name)|psi-mi:SPSB1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zheng et al. (2014) pubmed:25203322|imex:IM-23299 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9980326|imex:IM-23299-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005976.2|ensembl:ENSG00000124216(gene)|ensembl:ENST00000244050(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060536"(cartilage morphogenesis)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060806"(negative regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0060972"(left/right pattern formation)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070888"(E-box binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95863|rcsb pdb:2Y48|rcsb pdb:3W5K|rcsb pdb:3ZMT|rcsb pdb:4QLI|reactome:R-HSA-8943724|dip:DIP-50870N refseq:NP_079382.2|ensembl:ENSP00000330221|ensembl:ENSP00000350573|ensembl:ENSP00000366616|ensembl:ENSG00000171621(gene)|ensembl:ENST00000328089(transcript)|ensembl:ENST00000357898(transcript)|ensembl:ENST00000377399(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q96BD6|rcsb pdb:2JK9|rcsb pdb:3F2O|reactome:R-HSA-8951664|reactome:R-HSA-983168 - - - figure legend:Supp 1J|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2014/10/22 2014/11/19 rogid:HEYVT7IhYT1jTPJTYFPYfosBmmo9606 rogid:oILuoZD3/R7RwvYVRHWDTXMHctE9606 intact-crc:CBAB450F50BC19DE|rigid:cUtbecHBPlT/Tpo2dMhYQSCe5Mw false - ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)