#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8A3A5	uniprotkb:Q8A3A5	intact:EBI-9633303|ensemblbacteria:AAO78155	intact:EBI-9633303|ensemblbacteria:AAO78155	psi-mi:q8a3a5_bactn(display_long)|uniprotkb:BT_3049(locus name)	psi-mi:q8a3a5_bactn(display_long)|uniprotkb:BT_3049(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Zhang et al. (2014)	imex:IM-22940|pubmed:24995510	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9633296|imex:IM-22940-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_011108607.1|interpro:IPR011006(CheY-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR018062|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_811961.1|rcsb pdb:3V9F|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|ensemblbacteria:AAO78155(transcript)|ensemblbacteria:BT_3049(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005887"(integral component of plasma membrane)	interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_011108607.1|interpro:IPR011006(CheY-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR018062|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_811961.1|rcsb pdb:3V9F|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|ensemblbacteria:AAO78155(transcript)|ensemblbacteria:BT_3049(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005887"(integral component of plasma membrane)	rcsb pdb:3V9F	-	-	figure legend:t2 f1c f5 f6a f6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/25	2014/10/16	rogid:kkmfb7bMxggC9g4nF8x0yCnSvBg226186	rogid:kkmfb7bMxggC9g4nF8x0yCnSvBg226186	intact-crc:E9F57425DC1EA42F|rigid:93RvrpxX7mBi5BaX+A9xzrvzQ24	false	tandem tag:?-?	tandem tag:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q89YQ8	uniprotkb:Q89YQ8	intact:EBI-9633266|ensemblbacteria:AAO79778	intact:EBI-9633266|ensemblbacteria:AAO79778	psi-mi:q89yq8_bactn(display_long)|uniprotkb:BT_4673(locus name)	psi-mi:q89yq8_bactn(display_long)|uniprotkb:BT_4673(locus name)	psi-mi:"MI:0071"(molecular sieving)	Zhang et al. (2014)	imex:IM-22940|pubmed:24995510	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9633336|imex:IM-22940-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_813584.1|rcsb pdb:3OTT|rcsb pdb:3VA6|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:AAO79778(transcript)|ensemblbacteria:BT_4673(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)	interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_813584.1|rcsb pdb:3OTT|rcsb pdb:3VA6|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:AAO79778(transcript)|ensemblbacteria:BT_4673(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)	-	-	-	figure legend:F4B|comment:"Size-exclusion chromatography coupled with static light  scattering indicates that both sensor proteins appear to be in equilibrium among  monomers, dimers and higher-order oligomers in aqueous solution of 20 mM Tris-HCl,  pH8.5 (Figure 4A and 4B)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/25	2014/10/16	rogid:Cg0Rv25TQZhSreeC4bQ7sspyCmA226186	rogid:Cg0Rv25TQZhSreeC4bQ7sspyCmA226186	intact-crc:4C52A201B2DB7342|rigid:XaCGHSNvD2iP5jU/w5GL0Mbnx4Y	false	his tag:?-?	his tag:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8A3A5	uniprotkb:Q8A3A5	intact:EBI-9633303|ensemblbacteria:AAO78155	intact:EBI-9633303|ensemblbacteria:AAO78155	psi-mi:q8a3a5_bactn(display_long)|uniprotkb:BT_3049(locus name)	psi-mi:q8a3a5_bactn(display_long)|uniprotkb:BT_3049(locus name)	psi-mi:"MI:0071"(molecular sieving)	Zhang et al. (2014)	imex:IM-22940|pubmed:24995510	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9633345|imex:IM-22940-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_011108607.1|interpro:IPR011006(CheY-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR018062|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_811961.1|rcsb pdb:3V9F|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|ensemblbacteria:AAO78155(transcript)|ensemblbacteria:BT_3049(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005887"(integral component of plasma membrane)	interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_011108607.1|interpro:IPR011006(CheY-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR018062|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_811961.1|rcsb pdb:3V9F|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|ensemblbacteria:AAO78155(transcript)|ensemblbacteria:BT_3049(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005887"(integral component of plasma membrane)	-	-	-	figure legend:F4A|comment:"Size-exclusion chromatography coupled with static light scattering indicates that both sensor proteins appear to be in equilibrium among monomers, dimers and higher-order oligomers in aqueous solution of 20 mM Tris-HCl, pH8.5 (Figure 4A and 4B)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/25	2014/10/16	rogid:kkmfb7bMxggC9g4nF8x0yCnSvBg226186	rogid:kkmfb7bMxggC9g4nF8x0yCnSvBg226186	intact-crc:59408E4F4D905671|rigid:93RvrpxX7mBi5BaX+A9xzrvzQ24	false	tandem tag:?-?	tandem tag:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8A3A5	uniprotkb:Q8A3A5	intact:EBI-9633303|ensemblbacteria:AAO78155	intact:EBI-9633303|ensemblbacteria:AAO78155	psi-mi:q8a3a5_bactn(display_long)|uniprotkb:BT_3049(locus name)	psi-mi:q8a3a5_bactn(display_long)|uniprotkb:BT_3049(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Zhang et al. (2014)	imex:IM-22940|pubmed:24995510	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9633360|imex:IM-22940-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_011108607.1|interpro:IPR011006(CheY-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR018062|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_811961.1|rcsb pdb:3V9F|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|ensemblbacteria:AAO78155(transcript)|ensemblbacteria:BT_3049(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005887"(integral component of plasma membrane)	interpro:IPR013783(Immunoglobulin-like fold)|refseq:WP_011108607.1|interpro:IPR011006(CheY-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR018062|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_811961.1|rcsb pdb:3V9F|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0009927"(histidine phosphotransfer kinase activity)|ensemblbacteria:AAO78155(transcript)|ensemblbacteria:BT_3049(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005887"(integral component of plasma membrane)	-	-	-	figure legend:F4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/25	2014/10/16	rogid:kkmfb7bMxggC9g4nF8x0yCnSvBg226186	rogid:kkmfb7bMxggC9g4nF8x0yCnSvBg226186	intact-crc:C8340AFA3EA74027|rigid:93RvrpxX7mBi5BaX+A9xzrvzQ24	false	tandem tag:?-?	tandem tag:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q89YQ8	uniprotkb:Q89YQ8	intact:EBI-9633266|ensemblbacteria:AAO79778	intact:EBI-9633266|ensemblbacteria:AAO79778	psi-mi:q89yq8_bactn(display_long)|uniprotkb:BT_4673(locus name)	psi-mi:q89yq8_bactn(display_long)|uniprotkb:BT_4673(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Zhang et al. (2014)	imex:IM-22940|pubmed:24995510	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	taxid:226186(bactn)|taxid:226186("Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9633366|imex:IM-22940-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_813584.1|rcsb pdb:3OTT|rcsb pdb:3VA6|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:AAO79778(transcript)|ensemblbacteria:BT_4673(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)	interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR009057(Homeodomain-like)|interpro:IPR018060|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011110(Two component regulator propeller)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011123(Two component regulator three Y)|refseq:NP_813584.1|rcsb pdb:3OTT|rcsb pdb:3VA6|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036097|interpro:IPR036890|ensemblbacteria:AAO79778(transcript)|ensemblbacteria:BT_4673(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)	-	-	-	figure legend:F4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/25	2014/10/16	rogid:Cg0Rv25TQZhSreeC4bQ7sspyCmA226186	rogid:Cg0Rv25TQZhSreeC4bQ7sspyCmA226186	intact-crc:6233E133B6EAF172|rigid:XaCGHSNvD2iP5jU/w5GL0Mbnx4Y	false	his tag:?-?	his tag:?-?	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)