#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546405|imex:IM-22923-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	rcsb pdb:4MQV	-	-	figure legend:t1 f1 sf1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:878C5CF0EDBC8F57|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:5-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:P13051	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-1025947|uniprotkb:O00637|uniprotkb:O00719|uniprotkb:Q93028|uniprotkb:A8K5M6|uniprotkb:B2R8Y1|ensembl:ENSP00000242576	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:ung_human(display_long)|uniprotkb:UNG(gene name)|psi-mi:UNG(display_short)|uniprotkb:DGU(gene name synonym)|uniprotkb:UNG15(gene name synonym)|uniprotkb:UNG1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546637|imex:IM-22923-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_003353.1|refseq:NP_550433.1|ensembl:ENSG00000076248(gene)|ensembl:ENST00000242576(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045008"(depyrimidination)|go:"GO:0045190"(isotype switching)|go:"GO:0097510"(base-excision repair, AP site formation via deaminated base removal)|interpro:IPR002043(Uracil-DNA glycosylase)|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR018085|interpro:IPR036895|rcsb pdb:1AKZ|rcsb pdb:1DPU|rcsb pdb:1EMH|rcsb pdb:1EMJ|rcsb pdb:1Q3F|rcsb pdb:1SSP|rcsb pdb:1UGH|rcsb pdb:1YUO|rcsb pdb:2HXM|rcsb pdb:2OXM|rcsb pdb:2OYT|rcsb pdb:2SSP|rcsb pdb:3FCF|rcsb pdb:3FCI|rcsb pdb:3FCK|rcsb pdb:3FCL|rcsb pdb:3TKB|rcsb pdb:4SKN|rcsb pdb:5AYR|rcsb pdb:5JK7|rcsb pdb:6VBA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|dip:DIP-24194N	-	-	-	figure legend:f5b sf4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:21.5x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:pjzUi17Vpmhp1JddThFwPvNhZCE9606	intact-crc:2488C3B53679A0D5|rigid:vau+/sZs1NYoyQbUc5aqWtakjig	false	binding-associated region:201-270	mutation decreasing interaction:76-78|binding-associated region:66-91	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9BVW5	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-2515360|ensembl:ENSP00000261881|uniprotkb:Q9NWZ6|uniprotkb:B2CW64	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:tipin_human(display_long)|uniprotkb:TIPIN(gene name)|psi-mi:TIPIN(display_short)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546671|imex:IM-22923-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	ensembl:ENSG00000075131(gene)|ensembl:ENST00000261881(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0043111"(replication fork arrest)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|reactome:R-HSA-5693607|refseq:XP_011520045.1|refseq:NP_060328.2|refseq:XP_005254578.1|refseq:XP_005254579.1|refseq:NP_001276915.1|refseq:XP_006720657.1|refseq:XP_016877879.1|dip:DIP-53658N	-	-	-	figure legend:f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:14.6x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:vNvUsnDmodQH/QQqJBYYSbjIdKo9606	intact-crc:6B947653E7301EE2|rigid:hiO+7bCxI8LSEdxvsu6tkpHlvEI	false	binding-associated region:201-270	mutation decreasing interaction:195-195|binding-associated region:195-220	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546424|imex:IM-22923-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f3 sf5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:225D1985B8563351|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:5-30|mutation decreasing interaction:17-19	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:P13051	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-1025947|uniprotkb:O00637|uniprotkb:O00719|uniprotkb:Q93028|uniprotkb:A8K5M6|uniprotkb:B2R8Y1|ensembl:ENSP00000242576	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:ung_human(display_long)|uniprotkb:UNG(gene name)|psi-mi:UNG(display_short)|uniprotkb:DGU(gene name synonym)|uniprotkb:UNG15(gene name synonym)|uniprotkb:UNG1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546580|imex:IM-22923-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_003353.1|refseq:NP_550433.1|ensembl:ENSG00000076248(gene)|ensembl:ENST00000242576(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045008"(depyrimidination)|go:"GO:0045190"(isotype switching)|go:"GO:0097510"(base-excision repair, AP site formation via deaminated base removal)|interpro:IPR002043(Uracil-DNA glycosylase)|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR018085|interpro:IPR036895|rcsb pdb:1AKZ|rcsb pdb:1DPU|rcsb pdb:1EMH|rcsb pdb:1EMJ|rcsb pdb:1Q3F|rcsb pdb:1SSP|rcsb pdb:1UGH|rcsb pdb:1YUO|rcsb pdb:2HXM|rcsb pdb:2OXM|rcsb pdb:2OYT|rcsb pdb:2SSP|rcsb pdb:3FCF|rcsb pdb:3FCI|rcsb pdb:3FCK|rcsb pdb:3FCL|rcsb pdb:3TKB|rcsb pdb:4SKN|rcsb pdb:5AYR|rcsb pdb:5JK7|rcsb pdb:6VBA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|dip:DIP-24194N	-	-	-	figure legend:f5a t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:14.6x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:pjzUi17Vpmhp1JddThFwPvNhZCE9606	intact-crc:BDDF9BB8E51F89A2|rigid:vau+/sZs1NYoyQbUc5aqWtakjig	false	binding-associated region:201-270	mutation decreasing interaction:88-88|binding-associated region:66-91	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546515|imex:IM-22923-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:18.2x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:650947DCDFAB7C49|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:5-30|mutation decreasing interaction:5-5	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546489|imex:IM-22923-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:17.4x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:989D9F3363DF6434|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:5-30|mutation decreasing interaction:27-27	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546476|imex:IM-22923-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:25.6x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:F2AE5046899A30AD|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	mutation decreasing interaction:16-17|binding-associated region:5-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546463|imex:IM-22923-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:14.5x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:9C6F372AA42041AF|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:5-30|mutation decreasing interaction:17-19	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546452|imex:IM-22923-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:46.3x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:00609BFB61CA42CE|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:12-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546528|imex:IM-22923-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:23.1x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:E1CF2DCF0A67C279|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:5-30|mutation decreasing interaction:20-21	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546502|imex:IM-22923-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:22.3x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:59C22EDDBD73BBC6|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	mutation decreasing interaction:12-13|binding-associated region:5-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:P13051	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-1025947|uniprotkb:O00637|uniprotkb:O00719|uniprotkb:Q93028|uniprotkb:A8K5M6|uniprotkb:B2R8Y1|ensembl:ENSP00000242576	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:ung_human(display_long)|uniprotkb:UNG(gene name)|psi-mi:UNG(display_short)|uniprotkb:DGU(gene name synonym)|uniprotkb:UNG15(gene name synonym)|uniprotkb:UNG1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546567|imex:IM-22923-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_003353.1|refseq:NP_550433.1|ensembl:ENSG00000076248(gene)|ensembl:ENST00000242576(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045008"(depyrimidination)|go:"GO:0045190"(isotype switching)|go:"GO:0097510"(base-excision repair, AP site formation via deaminated base removal)|interpro:IPR002043(Uracil-DNA glycosylase)|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR018085|interpro:IPR036895|rcsb pdb:1AKZ|rcsb pdb:1DPU|rcsb pdb:1EMH|rcsb pdb:1EMJ|rcsb pdb:1Q3F|rcsb pdb:1SSP|rcsb pdb:1UGH|rcsb pdb:1YUO|rcsb pdb:2HXM|rcsb pdb:2OXM|rcsb pdb:2OYT|rcsb pdb:2SSP|rcsb pdb:3FCF|rcsb pdb:3FCI|rcsb pdb:3FCK|rcsb pdb:3FCL|rcsb pdb:3TKB|rcsb pdb:4SKN|rcsb pdb:5AYR|rcsb pdb:5JK7|rcsb pdb:6VBA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|dip:DIP-24194N	-	-	-	figure legend:f5a t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:21.5x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:pjzUi17Vpmhp1JddThFwPvNhZCE9606	intact-crc:032DB7A55BFEACA3|rigid:vau+/sZs1NYoyQbUc5aqWtakjig	false	binding-associated region:201-270	binding-associated region:66-91|mutation decreasing interaction:76-78	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9BVW5	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-2515360|ensembl:ENSP00000261881|uniprotkb:Q9NWZ6|uniprotkb:B2CW64	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:tipin_human(display_long)|uniprotkb:TIPIN(gene name)|psi-mi:TIPIN(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546593|imex:IM-22923-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	ensembl:ENSG00000075131(gene)|ensembl:ENST00000261881(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0043111"(replication fork arrest)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|reactome:R-HSA-5693607|refseq:XP_011520045.1|refseq:NP_060328.2|refseq:XP_005254578.1|refseq:XP_005254579.1|refseq:NP_001276915.1|refseq:XP_006720657.1|refseq:XP_016877879.1|dip:DIP-53658N	-	-	-	figure legend:f5c t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.1x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:vNvUsnDmodQH/QQqJBYYSbjIdKo9606	intact-crc:259BCFDE63D9C7E6|rigid:hiO+7bCxI8LSEdxvsu6tkpHlvEI	false	binding-associated region:201-270	binding-associated region:195-220	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9BVW5	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-2515360|ensembl:ENSP00000261881|uniprotkb:Q9NWZ6|uniprotkb:B2CW64	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:tipin_human(display_long)|uniprotkb:TIPIN(gene name)|psi-mi:TIPIN(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546608|imex:IM-22923-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	ensembl:ENSG00000075131(gene)|ensembl:ENST00000261881(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|go:"GO:0043111"(replication fork arrest)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|interpro:IPR012923(Replication fork protection component Swi3)|interpro:IPR040038|reactome:R-HSA-5693607|refseq:XP_011520045.1|refseq:NP_060328.2|refseq:XP_005254578.1|refseq:XP_005254579.1|refseq:NP_001276915.1|refseq:XP_006720657.1|refseq:XP_016877879.1|dip:DIP-53658N	-	-	-	figure legend:f5c t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:14.6x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:vNvUsnDmodQH/QQqJBYYSbjIdKo9606	intact-crc:1D624034F0E82A07|rigid:hiO+7bCxI8LSEdxvsu6tkpHlvEI	false	binding-associated region:201-270	binding-associated region:195-220|mutation decreasing interaction:195-195	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:P13051	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-1025947|uniprotkb:O00637|uniprotkb:O00719|uniprotkb:Q93028|uniprotkb:A8K5M6|uniprotkb:B2R8Y1|ensembl:ENSP00000242576	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:ung_human(display_long)|uniprotkb:UNG(gene name)|psi-mi:UNG(display_short)|uniprotkb:DGU(gene name synonym)|uniprotkb:UNG15(gene name synonym)|uniprotkb:UNG1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546554|imex:IM-22923-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_003353.1|refseq:NP_550433.1|ensembl:ENSG00000076248(gene)|ensembl:ENST00000242576(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045008"(depyrimidination)|go:"GO:0045190"(isotype switching)|go:"GO:0097510"(base-excision repair, AP site formation via deaminated base removal)|interpro:IPR002043(Uracil-DNA glycosylase)|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR018085|interpro:IPR036895|rcsb pdb:1AKZ|rcsb pdb:1DPU|rcsb pdb:1EMH|rcsb pdb:1EMJ|rcsb pdb:1Q3F|rcsb pdb:1SSP|rcsb pdb:1UGH|rcsb pdb:1YUO|rcsb pdb:2HXM|rcsb pdb:2OXM|rcsb pdb:2OYT|rcsb pdb:2SSP|rcsb pdb:3FCF|rcsb pdb:3FCI|rcsb pdb:3FCK|rcsb pdb:3FCL|rcsb pdb:3TKB|rcsb pdb:4SKN|rcsb pdb:5AYR|rcsb pdb:5JK7|rcsb pdb:6VBA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|dip:DIP-24194N	-	-	-	figure legend:f5a t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:6.6x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:pjzUi17Vpmhp1JddThFwPvNhZCE9606	intact-crc:DBFA0BCE6887B249|rigid:vau+/sZs1NYoyQbUc5aqWtakjig	false	binding-associated region:201-270	binding-associated region:66-91	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546541|imex:IM-22923-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:15.9x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:BFF12D650C7609F7|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	mutation decreasing interaction:9-9|binding-associated region:5-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546441|imex:IM-22923-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	-	-	-	figure legend:f4 t2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.9x10^-6(molar)	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:F29EC288DC5AB11F|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:5-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)
uniprotkb:P15927	uniprotkb:Q9NZC9	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Xie et al. (2014)	pubmed:24910198|imex:IM-22923	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9546692|imex:IM-22923-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N	refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation)	rcsb pdb:4MQV	-	-	figure legend:sf2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/06/06	2014/10/16	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	rogid:sUz7fctEmC8ajY7I9H474RGxhag9606	intact-crc:E860BF21B44D9F77|rigid:3lcTGyz/3yh1zSBskFxQrFTWLNI	false	binding-associated region:201-270	binding-associated region:5-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0083"(peptide synthesis)