#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P50461	uniprotkb:P50461	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:"MI:0047"(far western blotting)	Vafiadaki et al. (2014)	pubmed:24860983|imex:IM-22917	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9539785|imex:IM-22917-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	-	-	-	figure legend:f5b|comment:"blot overlay assays with the GST-MLP-b were performed. Western blot analysis with the GST antibody determined that  the isoform does not bind to MyoD or Myogenin (Fig. 5B), although it can directly  bind MLP, as detected by its interaction with MBP-MLP-a recombinant protein (Fig.  5B). In a parallel set of blot overlay assays we confirmed previous reports on the  direct interaction of full length MLP with MyoD and Myogenin (Fig. 5C)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/23	2016/11/30	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	intact-crc:40BCBAA9044BDCEE|rigid:BlssdV9SFuVAmAUZUZgjnagfpyU	false	maltose binding protein tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P50461	uniprotkb:P15173	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	intact:EBI-3906629|uniprotkb:Q53XW6|ensembl:ENSP00000241651	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:myog_human(display_long)|uniprotkb:MYOG(gene name)|psi-mi:MYOG(display_short)|uniprotkb:BHLHC3(gene name synonym)|uniprotkb:MYF4(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 3(gene name synonym)|uniprotkb:Myogenic factor 4(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Vafiadaki et al. (2014)	pubmed:24860983|imex:IM-22917	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9539806|imex:IM-22917-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	refseq:NP_002470.2|ensembl:ENSG00000122180(gene)|ensembl:ENST00000241651(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009629"(response to gravity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014873"(response to muscle activity involved in regulation of muscle adaptation)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0071259"(cellular response to magnetism)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|dip:DIP-159N	-	-	-	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/23	2014/10/16	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	rogid:7r8zPLBvho1GRHTAr7SVXjDXRxg9606	intact-crc:1AD8DCEA995C0650|rigid:yyHb4nKne1vztmC/J2mAnmfdcA0	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15172	uniprotkb:P50461	intact:EBI-488878|uniprotkb:O75321|ensembl:ENSP00000250003	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	psi-mi:myod1_human(display_long)|uniprotkb:Myogenic factor 3(gene name synonym)|uniprotkb:MYOD1(gene name)|psi-mi:MYOD1(display_short)|uniprotkb:MYF3(gene name synonym)|uniprotkb:MYOD(gene name synonym)|uniprotkb:BHLHC1(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 1(gene name synonym)	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:"MI:0047"(far western blotting)	Vafiadaki et al. (2014)	pubmed:24860983|imex:IM-22917	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9539796|imex:IM-22917-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002469.2|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007517"(muscle organ development)|go:"GO:0007518"(myoblast fate determination)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0014904"(myotube cell development)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030016"(myofibril)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000129152(gene)|ensembl:ENST00000250003(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000818"(negative regulation of myoblast proliferation)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR022032|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|dip:DIP-704N	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	-	-	-	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/23	2014/10/16	rogid:3VTNivTUfx8OwYeE2scVTkN11oY9606	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	intact-crc:10D71B4874F8D6F4|rigid:IFis9RguCQUm98oF7iAhkV8/XYc	false	his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P50461	uniprotkb:Q9Y281	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Vafiadaki et al. (2014)	pubmed:24860983|imex:IM-22917	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9539964|imex:IM-22917-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281	-	-	-	figure legend:f6h f6i|comment:"we performed competition assays by blot overlay using His-CFL2  and MBP-MLP-a in the presence or absence of the GST-MLP-b. The MLP/CFL2 interaction remained unaffected by the presence of the MLP-b,  indicating that the latter does not compete with CFL2 for binding to full length MLP  (Fig. 6H-I)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/23	2014/10/16	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	intact-crc:D5609FD4BD315E86|rigid:eA8QUHdtGYSsMTZVScFblic896M	false	maltose binding protein tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50461	uniprotkb:P50461	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:"MI:0047"(far western blotting)	Vafiadaki et al. (2014)	pubmed:24860983|imex:IM-22917	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9539925|imex:IM-22917-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	-	-	-	figure legend:f6e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/23	2016/11/30	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	intact-crc:93DDF23068FE092C|rigid:BlssdV9SFuVAmAUZUZgjnagfpyU	false	glutathione s tranferase tag:?-?	binding-associated region:64-117|maltose binding protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y281	uniprotkb:P50461	intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym)	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:"MI:0047"(far western blotting)	Vafiadaki et al. (2014)	pubmed:24860983|imex:IM-22917	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9539951|imex:IM-22917-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	-	-	-	figure legend:f6g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/23	2014/10/16	rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	intact-crc:9128EC55DFE204E9|rigid:eA8QUHdtGYSsMTZVScFblic896M	false	glutathione s tranferase tag:?-?	maltose binding protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50461	uniprotkb:P35609	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	intact:EBI-77797|uniprotkb:Q86TF4|ensembl:ENSP00000355537|uniprotkb:Q86TI8|uniprotkb:B1ANE4|intact:EBI-928705|uniprotkb:B2RCS5	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:actn2_human(display_long)|uniprotkb:ACTN2(gene name)|psi-mi:ACTN2(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 2(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vafiadaki et al. (2014)	pubmed:24860983|imex:IM-22917	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9539852|imex:IM-22917-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	refseq:NP_001094.1|ensembl:ENSG00000077522(gene)|ensembl:ENST00000366578(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:0030374"(nuclear receptor coactivator activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:P35609|rcsb pdb:1H8B|rcsb pdb:1HCI|rcsb pdb:1QUU|rcsb pdb:4D1E|rcsb pdb:5A36|rcsb pdb:5A37|rcsb pdb:5A38|rcsb pdb:5A4B|rcsb pdb:6SWT|rcsb pdb:6TS3|rcsb pdb:7A8T|rcsb pdb:7A8U|reactome:R-HSA-114608|go:"GO:2001259"(positive regulation of cation channel activity)|reactome:R-HSA-373753|reactome:R-HSA-390522|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|refseq:NP_001265272.1|refseq:NP_001265273.1|dip:DIP-383N	-	-	-	figure legend:f6c|comment:"In parallel, we performed pull down assays using GST-MLP-a, which served  as a positive control for these experiments (Fig. 6B). Western blot analysis of the pull  down samples determined that MLP-b can bind both to α-actinin and Tcap  (Fig. 6C)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/23	2014/10/16	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	rogid:9jws8DZxpttkzqPfDxEzORNnwcE9606	intact-crc:B29F5B0FD98B6F7A|rigid:hbDT7k8HMRasGCu+i6nSAkibgdE	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P50461	uniprotkb:O15273	intact:EBI-5658719|uniprotkb:Q9P131|intact:EBI-9540516|uniprotkb:S4S7M7|ensembl:ENSP00000265968|ensembl:ENSP00000431813|ensembl:ENSP00000497388	intact:EBI-954089|ensembl:ENSP00000312624|uniprotkb:Q96L27	psi-mi:csrp3_human(display_long)|uniprotkb:CLP(gene name synonym)|uniprotkb:Cardiac LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:MLP(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:CSRP3(gene name)|psi-mi:CSRP3(display_short)	psi-mi:telt_human(display_long)|uniprotkb:Titin cap protein(gene name synonym)|uniprotkb:TCAP(gene name)|psi-mi:TCAP(display_short)	psi-mi:"MI:0096"(pull down)	Vafiadaki et al. (2014)	pubmed:24860983|imex:IM-22917	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9539852|imex:IM-22917-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003467.1|ensembl:ENSG00000129170(gene)|ensembl:ENST00000265968(transcript)|ensembl:ENST00000533783(transcript)|ensembl:ENST00000649235(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2O10|rcsb pdb:2O13	ensembl:ENSG00000173991(gene)|ensembl:ENST00000309889(transcript)|go:"GO:0001756"(somitogenesis)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005829"(cytosol)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0031432"(titin binding)|go:"GO:0031674"(I band)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036122"(BMP binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051373"(FATZ binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070080"(titin Z domain binding)|interpro:IPR015667(Telethonin)|interpro:IPR023111|mint:O15273|rcsb pdb:1YA5|rcsb pdb:2F8V|reactome:R-HSA-390522|refseq:NP_003664.1|dip:DIP-35730N	-	-	-	figure legend:f6c|comment:"In parallel, we performed pull down assays using GST-MLP-a, which served  as a positive control for these experiments (Fig. 6B). Western blot analysis of the pull  down samples determined that MLP-b can bind both to α-actinin and Tcap  (Fig. 6C)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/05/23	2014/10/16	rogid:END0H7Mm0BQlKb0pQ3cEUoqXFmA9606	rogid:2Dfb7mWswRzoRh/YwYCWfzfTEu09606	intact-crc:B29F5B0FD98B6F7A|rigid:hbDT7k8HMRasGCu+i6nSAkibgdE	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)