#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:79045" uniprotkb:O95470 intact:EBI-9635161 intact:EBI-1046170|uniprotkb:Q7Z732|uniprotkb:Q9ULG8|uniprotkb:Q9UN89|uniprotkb:B2RBD4|ensembl:ENSP00000362298 psi-mi:compound_31(display_short)|psi-mi:"CHEBI:79045"(display_long) psi-mi:sgpl1_human(display_long)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:SGPL1(gene name)|psi-mi:SGPL1(display_short)|uniprotkb:KIAA1252(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Weiler et al. (2014) imex:IM-22906|pubmed:24809814 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-9548328|pdbe:4q6r|imex:IM-22906-1 - - psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_003892.2|refseq:XP_011538618.1|refseq:XP_011538619.1|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|ensembl:ENSG00000166224(gene)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENST00000373202(transcript)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|go:"GO:0001553"(luteinization)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:4Q6R|reactome:R-HSA-1660661|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:XP_005270320.1 - - - figure legend:Fig 4a/ Table 4|3d-resolution:2.40 A|3d-r-factors:"R-factor: 0.179, R-free: 0.206"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/06/10 2019/01/30 - rogid:hGut7nnomGA7QJhsV4lHBNm+kEE9606 intact-crc:7E29A9F23567C11A false - sufficient binding region:62-568(IPR015424)|N6-pyridoxal phosphate-L-lysine:353-353 - 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)