#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q920F6	uniprotkb:Q8C5S7	intact:EBI-8351315|intact:MINT-4134790|ensembl:ENSMUSP00000023068	intact:EBI-8571691|ensembl:ENSMUSP00000002395|uniprotkb:Q3UIN9|intact:UNK-5513402|uniprotkb:Q9JK52	psi-mi:smc1b_mouse(display_long)|uniprotkb:Smc1b(gene name)|psi-mi:Smc1b(display_short)|uniprotkb:Smc1l2(gene name synonym)	psi-mi:rec8_mouse(display_long)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:Rec8(gene name)|psi-mi:Rec8(display_short)|uniprotkb:Mei8(gene name synonym)|uniprotkb:Rec8L1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9699344|imex:IM-23075-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536718.1|ensembl:ENSMUSG00000022432(gene)|ensembl:ENSMUST00000023068(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|mint:Q920F6	ensembl:ENSMUSG00000002324(gene)|ensembl:ENSMUST00000002395(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007141"(male meiosis I)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|go:"GO:0003682"(chromatin binding)|refseq:NP_064386.2|dip:DIP-60730N	go:"GO:0005634"(nucleus)	comment:mint|function:"Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I"	comment:mint|function:Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II	figure legend:f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:1EEeJ21AepYX9+6+xmPXaVLtZ7810090	rogid:wcsRCrbsVBKW3reh5uW+EN080oU10090	intact-crc:3F14AD47CFADE36C|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q920F6	uniprotkb:O70576	intact:EBI-8351315|intact:MINT-4134790|ensembl:ENSMUSP00000023068	intact:EBI-8571608|ensembl:ENSMUSP00000040945|ensembl:ENSMUSP00000125523|intact:UNK-5365402|uniprotkb:B2RSV0	psi-mi:smc1b_mouse(display_long)|uniprotkb:Smc1b(gene name)|psi-mi:Smc1b(display_short)|uniprotkb:Smc1l2(gene name synonym)	psi-mi:stag3_mouse(display_long)|uniprotkb:Stromalin-3(gene name synonym)|uniprotkb:Stag3(gene name)|psi-mi:Stag3(display_short)|uniprotkb:Stromal antigen 3(gene name synonym)|uniprotkb:SCC3 homolog 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9699344|imex:IM-23075-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536718.1|ensembl:ENSMUSG00000022432(gene)|ensembl:ENSMUST00000023068(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|mint:Q920F6	refseq:XP_011239250.1|ensembl:ENSMUSG00000036928(gene)|ensembl:ENSMUST00000048028(transcript)|ensembl:ENSMUST00000162245(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0034991"(nuclear meiotic cohesin complex)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:O70576|refseq:XP_006504659.1|refseq:NP_058660.2|dip:DIP-60731N	go:"GO:0005634"(nucleus)	comment:mint|function:"Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I"	function:Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I|comment:mint	figure legend:f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:1EEeJ21AepYX9+6+xmPXaVLtZ7810090	rogid:VStlV0vm44TtcEnvNQTLPTFy2ok10090	intact-crc:3F14AD47CFADE36C|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q920F6	uniprotkb:A2AU37	intact:EBI-8351315|intact:MINT-4134790|ensembl:ENSMUSP00000023068	intact:EBI-8572441|ensembl:ENSMUSP00000136918|intact:MINT-8174264|uniprotkb:F6KST0|uniprotkb:E5RTP6|intact:MINT-8174092	psi-mi:smc1b_mouse(display_long)|uniprotkb:Smc1b(gene name)|psi-mi:Smc1b(display_short)|uniprotkb:Smc1l2(gene name synonym)	psi-mi:rd21l_mouse(display_long)|uniprotkb:Rad21l1(gene name)|psi-mi:Rad21l1(display_short)|uniprotkb:Gm14160(gene name synonym)|uniprotkb:Rad21l(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9699344|imex:IM-23075-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536718.1|ensembl:ENSMUSG00000022432(gene)|ensembl:ENSMUST00000023068(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|mint:Q920F6	ensembl:ENSMUSG00000074704(gene)|ensembl:ENSMUST00000180195(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|refseq:XP_006500105.1|refseq:XP_006500106.1|refseq:NP_001263329.1|dip:DIP-60729N	go:"GO:0005634"(nucleus)	comment:mint|function:"Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I"	comment:mint	figure legend:f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:1EEeJ21AepYX9+6+xmPXaVLtZ7810090	rogid:z8WZFTHSHhOOfT6F/EHl3GVaFEA10090	intact-crc:3F14AD47CFADE36C|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q920F6	uniprotkb:Q61550	intact:EBI-8351315|intact:MINT-4134790|ensembl:ENSMUSP00000023068	intact:EBI-2550110|uniprotkb:Q3TQ09|uniprotkb:Q810A8|ensembl:ENSMUSP00000022927|uniprotkb:P70219|uniprotkb:Q91VB9|uniprotkb:Q9DBU4	psi-mi:smc1b_mouse(display_long)|uniprotkb:Smc1b(gene name)|psi-mi:Smc1b(display_short)|uniprotkb:Smc1l2(gene name synonym)	psi-mi:rad21_mouse(display_long)|uniprotkb:Rad21(gene name)|psi-mi:Rad21(display_short)|uniprotkb:Hr21(gene name synonym)|uniprotkb:Pokeweed agglutinin-binding protein 29(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:Scc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9699344|imex:IM-23075-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536718.1|ensembl:ENSMUSG00000022432(gene)|ensembl:ENSMUST00000023068(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|mint:Q920F6	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:Q61550|reactome:R-MMU-2467813|reactome:R-MMU-2468052|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|ensembl:ENSMUSG00000022314(gene)|ensembl:ENSMUST00000022927(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|refseq:NP_033035.3|refseq:XP_006520707.1|refseq:XP_006520708.1|dip:DIP-56655N	go:"GO:0005634"(nucleus)	comment:mint|function:"Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I"	-	figure legend:f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:1EEeJ21AepYX9+6+xmPXaVLtZ7810090	rogid:TXbWgmegqmBbcsQxxC4t7A/nc3o10090	intact-crc:3F14AD47CFADE36C|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q920F6	uniprotkb:Q9CU62	intact:EBI-8351315|intact:MINT-4134790|ensembl:ENSMUSP00000023068	intact:EBI-2550016|uniprotkb:A2AFQ5|ensembl:ENSMUSP00000044645|uniprotkb:Q3V480|uniprotkb:Q9CUX9|uniprotkb:Q9D959|uniprotkb:Q9WTU1	psi-mi:smc1b_mouse(display_long)|uniprotkb:Smc1b(gene name)|psi-mi:Smc1b(display_short)|uniprotkb:Smc1l2(gene name synonym)	psi-mi:smc1a_mouse(display_long)|uniprotkb:Smc1a(gene name)|psi-mi:Smc1a(display_short)|uniprotkb:Smc1(gene name synonym)|uniprotkb:Smc1l1(gene name synonym)|uniprotkb:Smcb(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)|uniprotkb:Chromosome segregation protein SmcB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9699344|imex:IM-23075-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536718.1|ensembl:ENSMUSG00000022432(gene)|ensembl:ENSMUST00000023068(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|mint:Q920F6	ensembl:ENSMUSG00000041133(gene)|ensembl:ENSMUST00000045312(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|go:"GO:0008278"(cohesin complex)|interpro:IPR036277|mint:Q9CU62|rcsb pdb:2WD5|reactome:R-MMU-2467813|interpro:IPR029683|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|refseq:NP_062684.2|dip:DIP-57021N	go:"GO:0005634"(nucleus)	comment:mint|function:"Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I"	-	figure legend:f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:1EEeJ21AepYX9+6+xmPXaVLtZ7810090	rogid:3TtjC4Y8krgvnUafgy2DG2XTnH810090	intact-crc:3F14AD47CFADE36C|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q920F6	uniprotkb:Q9CW03	intact:EBI-8351315|intact:MINT-4134790|ensembl:ENSMUSP00000023068	intact:EBI-2550068|ensembl:ENSMUSP00000025930|uniprotkb:O35667|uniprotkb:Q9QUS3	psi-mi:smc1b_mouse(display_long)|uniprotkb:Smc1b(gene name)|psi-mi:Smc1b(display_short)|uniprotkb:Smc1l2(gene name synonym)	psi-mi:smc3_mouse(display_long)|uniprotkb:Smc3(gene name)|psi-mi:Smc3(display_short)|uniprotkb:Bam(gene name synonym)|uniprotkb:Bmh(gene name synonym)|uniprotkb:Cspg6(gene name synonym)|uniprotkb:Mmip1(gene name synonym)|uniprotkb:Smc3l1(gene name synonym)|uniprotkb:Smcd(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome segregation protein SmcD(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:Mad member-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9699344|imex:IM-23075-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_536718.1|ensembl:ENSMUSG00000022432(gene)|ensembl:ENSMUST00000023068(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|mint:Q920F6	ensembl:ENSMUSG00000024974(gene)|ensembl:ENSMUST00000025930(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9CW03|rcsb pdb:2WD5|reactome:R-MMU-2467813|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|refseq:NP_031816.2|dip:DIP-57028N	go:"GO:0005634"(nucleus)	comment:mint|function:"Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I"	-	figure legend:f5d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:1EEeJ21AepYX9+6+xmPXaVLtZ7810090	rogid:9tJqVTJ2k3viYrJVtDfH2TekFIg10090	intact-crc:3F14AD47CFADE36C|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2AU37	uniprotkb:O70576	intact:EBI-8572441|ensembl:ENSMUSP00000136918|intact:MINT-8174264|uniprotkb:F6KST0|uniprotkb:E5RTP6|intact:MINT-8174092	intact:EBI-8571608|ensembl:ENSMUSP00000040945|ensembl:ENSMUSP00000125523|intact:UNK-5365402|uniprotkb:B2RSV0	psi-mi:rd21l_mouse(display_long)|uniprotkb:Rad21l1(gene name)|psi-mi:Rad21l1(display_short)|uniprotkb:Gm14160(gene name synonym)|uniprotkb:Rad21l(gene name synonym)	psi-mi:stag3_mouse(display_long)|uniprotkb:Stromalin-3(gene name synonym)|uniprotkb:Stag3(gene name)|psi-mi:Stag3(display_short)|uniprotkb:Stromal antigen 3(gene name synonym)|uniprotkb:SCC3 homolog 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9700378|imex:IM-23075-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000074704(gene)|ensembl:ENSMUST00000180195(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|refseq:XP_006500105.1|refseq:XP_006500106.1|refseq:NP_001263329.1|dip:DIP-60729N	refseq:XP_011239250.1|ensembl:ENSMUSG00000036928(gene)|ensembl:ENSMUST00000048028(transcript)|ensembl:ENSMUST00000162245(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0000802"(transverse filament)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007065"(male meiosis sister chromatid cohesion)|go:"GO:0007066"(female meiosis sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0034991"(nuclear meiotic cohesin complex)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:O70576|refseq:XP_006504659.1|refseq:NP_058660.2|dip:DIP-60731N	go:"GO:0005634"(nucleus)	comment:mint	function:Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I|comment:mint	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:z8WZFTHSHhOOfT6F/EHl3GVaFEA10090	rogid:VStlV0vm44TtcEnvNQTLPTFy2ok10090	intact-crc:4BA17CDFD75BCC91|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2AU37	uniprotkb:Q920F6	intact:EBI-8572441|ensembl:ENSMUSP00000136918|intact:MINT-8174264|uniprotkb:F6KST0|uniprotkb:E5RTP6|intact:MINT-8174092	intact:EBI-8351315|intact:MINT-4134790|ensembl:ENSMUSP00000023068	psi-mi:rd21l_mouse(display_long)|uniprotkb:Rad21l1(gene name)|psi-mi:Rad21l1(display_short)|uniprotkb:Gm14160(gene name synonym)|uniprotkb:Rad21l(gene name synonym)	psi-mi:smc1b_mouse(display_long)|uniprotkb:Smc1b(gene name)|psi-mi:Smc1b(display_short)|uniprotkb:Smc1l2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9700378|imex:IM-23075-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000074704(gene)|ensembl:ENSMUST00000180195(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|refseq:XP_006500105.1|refseq:XP_006500106.1|refseq:NP_001263329.1|dip:DIP-60729N	refseq:NP_536718.1|ensembl:ENSMUSG00000022432(gene)|ensembl:ENSMUST00000023068(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|mint:Q920F6	go:"GO:0005634"(nucleus)	comment:mint	comment:mint|function:"Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I"	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:z8WZFTHSHhOOfT6F/EHl3GVaFEA10090	rogid:1EEeJ21AepYX9+6+xmPXaVLtZ7810090	intact-crc:4BA17CDFD75BCC91|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2AU37	uniprotkb:Q8C5S7	intact:EBI-8572441|ensembl:ENSMUSP00000136918|intact:MINT-8174264|uniprotkb:F6KST0|uniprotkb:E5RTP6|intact:MINT-8174092	intact:EBI-8571691|ensembl:ENSMUSP00000002395|uniprotkb:Q3UIN9|intact:UNK-5513402|uniprotkb:Q9JK52	psi-mi:rd21l_mouse(display_long)|uniprotkb:Rad21l1(gene name)|psi-mi:Rad21l1(display_short)|uniprotkb:Gm14160(gene name synonym)|uniprotkb:Rad21l(gene name synonym)	psi-mi:rec8_mouse(display_long)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:Rec8(gene name)|psi-mi:Rec8(display_short)|uniprotkb:Mei8(gene name synonym)|uniprotkb:Rec8L1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9700378|imex:IM-23075-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000074704(gene)|ensembl:ENSMUST00000180195(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|refseq:XP_006500105.1|refseq:XP_006500106.1|refseq:NP_001263329.1|dip:DIP-60729N	ensembl:ENSMUSG00000002324(gene)|ensembl:ENSMUST00000002395(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007141"(male meiosis I)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|go:"GO:0003682"(chromatin binding)|refseq:NP_064386.2|dip:DIP-60730N	go:"GO:0005634"(nucleus)	comment:mint	comment:mint|function:Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:z8WZFTHSHhOOfT6F/EHl3GVaFEA10090	rogid:wcsRCrbsVBKW3reh5uW+EN080oU10090	intact-crc:4BA17CDFD75BCC91|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2AU37	uniprotkb:Q9CU62	intact:EBI-8572441|ensembl:ENSMUSP00000136918|intact:MINT-8174264|uniprotkb:F6KST0|uniprotkb:E5RTP6|intact:MINT-8174092	intact:EBI-2550016|uniprotkb:A2AFQ5|ensembl:ENSMUSP00000044645|uniprotkb:Q3V480|uniprotkb:Q9CUX9|uniprotkb:Q9D959|uniprotkb:Q9WTU1	psi-mi:rd21l_mouse(display_long)|uniprotkb:Rad21l1(gene name)|psi-mi:Rad21l1(display_short)|uniprotkb:Gm14160(gene name synonym)|uniprotkb:Rad21l(gene name synonym)	psi-mi:smc1a_mouse(display_long)|uniprotkb:Smc1a(gene name)|psi-mi:Smc1a(display_short)|uniprotkb:Smc1(gene name synonym)|uniprotkb:Smc1l1(gene name synonym)|uniprotkb:Smcb(gene name synonym)|uniprotkb:Sb1.8(gene name synonym)|uniprotkb:Chromosome segregation protein SmcB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9700378|imex:IM-23075-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000074704(gene)|ensembl:ENSMUST00000180195(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|refseq:XP_006500105.1|refseq:XP_006500106.1|refseq:NP_001263329.1|dip:DIP-60729N	ensembl:ENSMUSG00000041133(gene)|ensembl:ENSMUST00000045312(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|go:"GO:0008278"(cohesin complex)|interpro:IPR036277|mint:Q9CU62|rcsb pdb:2WD5|reactome:R-MMU-2467813|interpro:IPR029683|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|refseq:NP_062684.2|dip:DIP-57021N	go:"GO:0005634"(nucleus)	comment:mint	-	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:z8WZFTHSHhOOfT6F/EHl3GVaFEA10090	rogid:3TtjC4Y8krgvnUafgy2DG2XTnH810090	intact-crc:4BA17CDFD75BCC91|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2AU37	uniprotkb:Q9CW03	intact:EBI-8572441|ensembl:ENSMUSP00000136918|intact:MINT-8174264|uniprotkb:F6KST0|uniprotkb:E5RTP6|intact:MINT-8174092	intact:EBI-2550068|ensembl:ENSMUSP00000025930|uniprotkb:O35667|uniprotkb:Q9QUS3	psi-mi:rd21l_mouse(display_long)|uniprotkb:Rad21l1(gene name)|psi-mi:Rad21l1(display_short)|uniprotkb:Gm14160(gene name synonym)|uniprotkb:Rad21l(gene name synonym)	psi-mi:smc3_mouse(display_long)|uniprotkb:Smc3(gene name)|psi-mi:Smc3(display_short)|uniprotkb:Bam(gene name synonym)|uniprotkb:Bmh(gene name synonym)|uniprotkb:Cspg6(gene name synonym)|uniprotkb:Mmip1(gene name synonym)|uniprotkb:Smc3l1(gene name synonym)|uniprotkb:Smcd(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome segregation protein SmcD(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:Mad member-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9700378|imex:IM-23075-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000074704(gene)|ensembl:ENSMUST00000180195(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|refseq:XP_006500105.1|refseq:XP_006500106.1|refseq:NP_001263329.1|dip:DIP-60729N	ensembl:ENSMUSG00000024974(gene)|ensembl:ENSMUST00000025930(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9CW03|rcsb pdb:2WD5|reactome:R-MMU-2467813|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|refseq:NP_031816.2|dip:DIP-57028N	go:"GO:0005634"(nucleus)	comment:mint	-	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:z8WZFTHSHhOOfT6F/EHl3GVaFEA10090	rogid:9tJqVTJ2k3viYrJVtDfH2TekFIg10090	intact-crc:4BA17CDFD75BCC91|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2AU37	uniprotkb:Q61550	intact:EBI-8572441|ensembl:ENSMUSP00000136918|intact:MINT-8174264|uniprotkb:F6KST0|uniprotkb:E5RTP6|intact:MINT-8174092	intact:EBI-2550110|uniprotkb:Q3TQ09|uniprotkb:Q810A8|ensembl:ENSMUSP00000022927|uniprotkb:P70219|uniprotkb:Q91VB9|uniprotkb:Q9DBU4	psi-mi:rd21l_mouse(display_long)|uniprotkb:Rad21l1(gene name)|psi-mi:Rad21l1(display_short)|uniprotkb:Gm14160(gene name synonym)|uniprotkb:Rad21l(gene name synonym)	psi-mi:rad21_mouse(display_long)|uniprotkb:Rad21(gene name)|psi-mi:Rad21(display_short)|uniprotkb:Hr21(gene name synonym)|uniprotkb:Pokeweed agglutinin-binding protein 29(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:Scc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fukuda et al. (2014)	pubmed:24797475|imex:IM-23075	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9700378|imex:IM-23075-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000074704(gene)|ensembl:ENSMUST00000180195(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0070197"(meiotic attachment of telomere to nuclear envelope)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|refseq:XP_006500105.1|refseq:XP_006500106.1|refseq:NP_001263329.1|dip:DIP-60729N	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:Q61550|reactome:R-MMU-2467813|reactome:R-MMU-2468052|go:"GO:0003682"(chromatin binding)|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|ensembl:ENSMUSG00000022314(gene)|ensembl:ENSMUST00000022927(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|refseq:NP_033035.3|refseq:XP_006520707.1|refseq:XP_006520708.1|dip:DIP-56655N	go:"GO:0005634"(nucleus)	comment:mint	-	figure legend:f5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-spermatocyte)|taxid:10090(Mus musculus)	-	2014/09/08	2014/10/16	rogid:z8WZFTHSHhOOfT6F/EHl3GVaFEA10090	rogid:TXbWgmegqmBbcsQxxC4t7A/nc3o10090	intact-crc:4BA17CDFD75BCC91|rigid:VRwaHMKJQ31o4fWs1gZdbRFkSD8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)