#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G5ECA1 uniprotkb:G5ECA1 intact:EBI-9526485|ensemblmetazoa:C26D10.5a.1 intact:EBI-9526485|ensemblmetazoa:C26D10.5a.1 psi-mi:g5eca1_caeel(display_long)|uniprotkb:eff-1(gene name)|psi-mi:eff-1(display_short)|uniprotkb:C26D10.5(orf name)|uniprotkb:CELE_C26D10.5(orf name) psi-mi:g5eca1_caeel(display_long)|uniprotkb:eff-1(gene name)|psi-mi:eff-1(display_short)|uniprotkb:C26D10.5(orf name)|uniprotkb:CELE_C26D10.5(orf name) psi-mi:"MI:0114"(x-ray crystallography) Pérez-Vargas et al. (2014) pubmed:24725407|imex:IM-22581 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9526517|wwpdb:4oje|imex:IM-22581-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4CYL|rcsb pdb:4OJC|rcsb pdb:4OJD|rcsb pdb:4OJE|refseq:NP_001021987.1|wormbase:C26D10.5a|interpro:IPR029213|interpro:IPR043076|go:"GO:0007275"(multicellular organism development)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0090597"(nematode male tail mating organ morphogenesis)|go:"GO:0140253"(cell-cell fusion)|ensemblmetazoa:C26D10.5a.1(transcript)|ensemblmetazoa:WBGene00001159(gene)|go:"GO:0000768"(syncytium formation by plasma membrane fusion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane) rcsb pdb:4CYL|rcsb pdb:4OJC|rcsb pdb:4OJD|rcsb pdb:4OJE|refseq:NP_001021987.1|wormbase:C26D10.5a|interpro:IPR029213|interpro:IPR043076|go:"GO:0007275"(multicellular organism development)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0090597"(nematode male tail mating organ morphogenesis)|go:"GO:0140253"(cell-cell fusion)|ensemblmetazoa:C26D10.5a.1(transcript)|ensemblmetazoa:WBGene00001159(gene)|go:"GO:0000768"(syncytium formation by plasma membrane fusion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane) - - - 3d-r-factors:Rworking = 0.18 Rfree = 0.22|3d-resolution:2.6A|figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/05/16 2014/10/16 rogid:yWxIVBqBdjBwmkr0VemTJi62lek6239 rogid:yWxIVBqBdjBwmkr0VemTJi62lek6239 intact-crc:7840456F361D6625|rigid:FMXrj/vpgtVM36B8hibzFGhqluw false sufficient binding region:23-509 sufficient binding region:23-509 3 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5ECA1 uniprotkb:G5ECA1 intact:EBI-9526485|ensemblmetazoa:C26D10.5a.1 intact:EBI-9526485|ensemblmetazoa:C26D10.5a.1 psi-mi:g5eca1_caeel(display_long)|uniprotkb:eff-1(gene name)|psi-mi:eff-1(display_short)|uniprotkb:C26D10.5(orf name)|uniprotkb:CELE_C26D10.5(orf name) psi-mi:g5eca1_caeel(display_long)|uniprotkb:eff-1(gene name)|psi-mi:eff-1(display_short)|uniprotkb:C26D10.5(orf name)|uniprotkb:CELE_C26D10.5(orf name) psi-mi:"MI:0114"(x-ray crystallography) Pérez-Vargas et al. (2014) pubmed:24725407|imex:IM-22581 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9526525|wwpdb:4oje|imex:IM-22581-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4CYL|rcsb pdb:4OJC|rcsb pdb:4OJD|rcsb pdb:4OJE|refseq:NP_001021987.1|wormbase:C26D10.5a|interpro:IPR029213|interpro:IPR043076|go:"GO:0007275"(multicellular organism development)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0090597"(nematode male tail mating organ morphogenesis)|go:"GO:0140253"(cell-cell fusion)|ensemblmetazoa:C26D10.5a.1(transcript)|ensemblmetazoa:WBGene00001159(gene)|go:"GO:0000768"(syncytium formation by plasma membrane fusion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane) rcsb pdb:4CYL|rcsb pdb:4OJC|rcsb pdb:4OJD|rcsb pdb:4OJE|refseq:NP_001021987.1|wormbase:C26D10.5a|interpro:IPR029213|interpro:IPR043076|go:"GO:0007275"(multicellular organism development)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0090597"(nematode male tail mating organ morphogenesis)|go:"GO:0140253"(cell-cell fusion)|ensemblmetazoa:C26D10.5a.1(transcript)|ensemblmetazoa:WBGene00001159(gene)|go:"GO:0000768"(syncytium formation by plasma membrane fusion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane) - - - 3d-r-factors:Rworking = 0.2 Rfree = 0.22|3d-resolution:2.3A|figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/05/16 2014/10/16 rogid:yWxIVBqBdjBwmkr0VemTJi62lek6239 rogid:yWxIVBqBdjBwmkr0VemTJi62lek6239 intact-crc:764A4A9B264C3260|rigid:FMXrj/vpgtVM36B8hibzFGhqluw false sufficient binding region:23-509|mutation:321-322,260-260 sufficient binding region:23-509|mutation:321-322,260-260 3 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5ECA1 uniprotkb:G5ECA1 intact:EBI-9526485|ensemblmetazoa:C26D10.5a.1 intact:EBI-9526485|ensemblmetazoa:C26D10.5a.1 psi-mi:g5eca1_caeel(display_long)|uniprotkb:eff-1(gene name)|psi-mi:eff-1(display_short)|uniprotkb:C26D10.5(orf name)|uniprotkb:CELE_C26D10.5(orf name) psi-mi:g5eca1_caeel(display_long)|uniprotkb:eff-1(gene name)|psi-mi:eff-1(display_short)|uniprotkb:C26D10.5(orf name)|uniprotkb:CELE_C26D10.5(orf name) psi-mi:"MI:0114"(x-ray crystallography) Pérez-Vargas et al. (2014) pubmed:24725407|imex:IM-22581 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9526508|wwpdb:4ojc|imex:IM-22581-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4CYL|rcsb pdb:4OJC|rcsb pdb:4OJD|rcsb pdb:4OJE|refseq:NP_001021987.1|wormbase:C26D10.5a|interpro:IPR029213|interpro:IPR043076|go:"GO:0007275"(multicellular organism development)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0090597"(nematode male tail mating organ morphogenesis)|go:"GO:0140253"(cell-cell fusion)|ensemblmetazoa:C26D10.5a.1(transcript)|ensemblmetazoa:WBGene00001159(gene)|go:"GO:0000768"(syncytium formation by plasma membrane fusion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane) rcsb pdb:4CYL|rcsb pdb:4OJC|rcsb pdb:4OJD|rcsb pdb:4OJE|refseq:NP_001021987.1|wormbase:C26D10.5a|interpro:IPR029213|interpro:IPR043076|go:"GO:0007275"(multicellular organism development)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0090597"(nematode male tail mating organ morphogenesis)|go:"GO:0140253"(cell-cell fusion)|ensemblmetazoa:C26D10.5a.1(transcript)|ensemblmetazoa:WBGene00001159(gene)|go:"GO:0000768"(syncytium formation by plasma membrane fusion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane) - - - 3d-r-factors:Rworking = 0.22 Rfree = 0.28|3d-resolution:2.9A|figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/05/16 2014/10/16 rogid:yWxIVBqBdjBwmkr0VemTJi62lek6239 rogid:yWxIVBqBdjBwmkr0VemTJi62lek6239 intact-crc:B549F8AD8B7D662C|rigid:FMXrj/vpgtVM36B8hibzFGhqluw false sufficient binding region:23-561 sufficient binding region:23-561 3 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:G5ECA1 uniprotkb:G5ECA1 intact:EBI-9526485|ensemblmetazoa:C26D10.5a.1 intact:EBI-9526485|ensemblmetazoa:C26D10.5a.1 psi-mi:g5eca1_caeel(display_long)|uniprotkb:eff-1(gene name)|psi-mi:eff-1(display_short)|uniprotkb:C26D10.5(orf name)|uniprotkb:CELE_C26D10.5(orf name) psi-mi:g5eca1_caeel(display_long)|uniprotkb:eff-1(gene name)|psi-mi:eff-1(display_short)|uniprotkb:C26D10.5(orf name)|uniprotkb:CELE_C26D10.5(orf name) psi-mi:"MI:0071"(molecular sieving) Pérez-Vargas et al. (2014) pubmed:24725407|imex:IM-22581 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-9526555|imex:IM-22581-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4CYL|rcsb pdb:4OJC|rcsb pdb:4OJD|rcsb pdb:4OJE|refseq:NP_001021987.1|wormbase:C26D10.5a|interpro:IPR029213|interpro:IPR043076|go:"GO:0007275"(multicellular organism development)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0090597"(nematode male tail mating organ morphogenesis)|go:"GO:0140253"(cell-cell fusion)|ensemblmetazoa:C26D10.5a.1(transcript)|ensemblmetazoa:WBGene00001159(gene)|go:"GO:0000768"(syncytium formation by plasma membrane fusion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane) rcsb pdb:4CYL|rcsb pdb:4OJC|rcsb pdb:4OJD|rcsb pdb:4OJE|refseq:NP_001021987.1|wormbase:C26D10.5a|interpro:IPR029213|interpro:IPR043076|go:"GO:0007275"(multicellular organism development)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0040011"(locomotion)|go:"GO:0040025"(vulval development)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0090597"(nematode male tail mating organ morphogenesis)|go:"GO:0140253"(cell-cell fusion)|ensemblmetazoa:C26D10.5a.1(transcript)|ensemblmetazoa:WBGene00001159(gene)|go:"GO:0000768"(syncytium formation by plasma membrane fusion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane) - - - figure legend:Fig. 4B, Supp 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/05/16 2014/10/16 rogid:yWxIVBqBdjBwmkr0VemTJi62lek6239 rogid:yWxIVBqBdjBwmkr0VemTJi62lek6239 intact-crc:E30DA26D31CF6636|rigid:FMXrj/vpgtVM36B8hibzFGhqluw false mutation disrupting interaction strength:260-260,321-322|mutation decreasing interaction strength:321-322|sufficient binding region:23-509|mutation decreasing interaction strength:260-260 mutation disrupting interaction strength:260-260,321-322|mutation decreasing interaction strength:321-322|sufficient binding region:23-509|mutation decreasing interaction strength:260-260 3 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)