#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q61169	uniprotkb:P46152	intact:EBI-8065049|uniprotkb:Q9QZK3|intact:MINT-1782188|uniprotkb:Q3UQJ2|uniprotkb:P97729|ensembl:ENSMUSP00000041774	intact:EBI-9257939|ensembl:ENSRNOP00000014320	psi-mi:gata6_mouse(display_long)|uniprotkb:Gata6(gene name)|psi-mi:Gata6(display_short)|uniprotkb:GATA-binding factor 6(gene name synonym)	psi-mi:gata4_rat(display_long)|uniprotkb:Gata4(gene name)|psi-mi:Gata4(display_short)|uniprotkb:DNA-binding protein GATA-GT2(gene name synonym)|uniprotkb:GATA-binding factor 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kee et al. (2014)	pubmed:24662306|imex:IM-22555	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9255098|imex:IM-22555-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034388.2|go:"GO:0032526"(response to retinoic acid)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007493"(endodermal cell fate determination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032912"(negative regulation of transforming growth factor beta2 production)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031016"(pancreas development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048645"(animal organ formation)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070848"(response to growth factor)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0098773"(skin epidermis development)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1901390"(positive regulation of transforming growth factor beta activation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1904003"(negative regulation of sebum secreting cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR028437|interpro:IPR039355|reactome:R-MMU-5683826|reactome:R-MMU-983231|ensembl:ENSMUSG00000005836(gene)|ensembl:ENSMUST00000047762(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001949"(sebaceous gland cell differentiation)|go:"GO:0002759"(regulation of antimicrobial humoral response)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)	rgd:2665|refseq:NP_653331.1|dip:DIP-60791N|ensembl:ENSRNOG00000010708(gene)|ensembl:ENSRNOT00000014320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001706"(endoderm formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0033189"(response to vitamin A)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035054"(embryonic heart tube anterior/posterior pattern specification)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060464"(lung lobe formation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0072148"(epithelial cell fate commitment)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1905204"(negative regulation of connective tissue replacement)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016375(Transcription factor GATA-4/5/6)|interpro:IPR039355|reactome:R-RNO-983231	-	comment:mint|function:Transcriptional activator. Involved in gene regulation specifically in the gastric epithelium	-	figure legend:f4e f4f|comment:"We further investigated whether the potentiation of GATA4/GATA6-mediated  transactivation of the ANP promoter was attributable to binding of GATA4 to GATA6.  Immunoprecipitation revealed that GATA4 physically interacted with GATA6 in 293T cells  11  (Fig. 4E). Treatment of piceatannol in 293T cells co-transfected with GATA4 and GATA6  reduced the interaction between GATA4 and GATA6 (Fig. 4F)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/03/10	2014/10/16	rogid:+/EaZWnNKhcYt9x7ugHoBDbKg3Q10090	rogid:/Eioiv9DiqnhUGqX6wsmHZDSpf810116	intact-crc:8C9EDC821BCD5CA9|rigid:EYqTGTEmiViIgzZc5ZqmHupVHb8	false	v5 tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)