#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:F1QVN7 uniprotkb:Q7T2E1 intact:EBI-9992961|ensembl:ENSDARP00000101727 intact:EBI-9993558|ensembl:ENSDARP00000071531 psi-mi:f1qvn7_danre(display_long)|uniprotkb:ift88(gene name)|psi-mi:ift88(display_short) psi-mi:q7t2e1_danre(display_long)|uniprotkb:Protein SEC13 homolog(gene name synonym)|uniprotkb:sec13(gene name)|psi-mi:sec13(display_short)|uniprotkb:sec13l1(gene name synonym)|uniprotkb:DKEY-72G22.2-001(orf name) psi-mi:"MI:0813"(proximity ligation assay) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9993539|imex:IM-23508-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005167586.1|ensembl:ENSDARG00000027234(gene)|ensembl:ENSDART00000110943(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007369"(gastrulation)|go:"GO:0019894"(kinesin binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0072019"(proximal convoluted tubule development)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-DRE-5610787|reactome:R-DRE-5620924|reactome:R-DRE-9646399 ensembl:ENSDARG00000054807(gene)|ensembl:ENSDART00000077063(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0010842"(retina layer formation)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0036372"(opsin transport)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0051028"(mRNA transport)|go:"GO:0055123"(digestive system development)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|go:"GO:0051216"(cartilage development)|refseq:NP_998500.1 go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0044297"(cell body) - - figure legend:5C,M,W|comment:The interaction was much reduced in cells not expressing ift88 or cdh23|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:QlsY9Zd04b1DKhN5950Bf3/Ray47955 rogid:h/eIIIRXB8BbR0izMEOrLzVJysc7955 intact-crc:ADFA760FB3F7D312|rigid:7R8qQ+6IdFJXxE2BpcUNMsr5DcY false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q6QQE1 uniprotkb:F1QVN7 intact:EBI-9992880 intact:EBI-9992961|ensembl:ENSDARP00000101727 psi-mi:q6qqe1_danre(display_long)|uniprotkb:cdh23(gene name)|psi-mi:cdh23(display_short) psi-mi:f1qvn7_danre(display_long)|uniprotkb:ift88(gene name)|psi-mi:ift88(display_short) psi-mi:"MI:0813"(proximity ligation assay) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9993146|imex:IM-23508-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|refseq:NP_999974.1|interpro:IPR033030|go:"GO:0005509"(calcium ion binding)|go:"GO:0005929"(cilium)|go:"GO:0006897"(endocytosis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030030"(cell projection organization)|go:"GO:0032420"(stereocilium)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035678"(neuromast hair cell morphogenesis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050957"(equilibrioception)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules) refseq:XP_005167586.1|ensembl:ENSDARG00000027234(gene)|ensembl:ENSDART00000110943(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007369"(gastrulation)|go:"GO:0019894"(kinesin binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0072019"(proximal convoluted tubule development)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-DRE-5610787|reactome:R-DRE-5620924|reactome:R-DRE-9646399 go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0044297"(cell body) - - figure legend:3B, H|comment:Labeling was greatly reduced or lost when any one protein was not expressed; the exception being for the mutant not expressing cdh23, as some signal remained for Cdh23-Harmonin,Cdh23-Ift88 and Harmonin-Ift88 protein pairs.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:1dvJx7emPY30Fw0IjfhSjl08IO87955 rogid:QlsY9Zd04b1DKhN5950Bf3/Ray47955 intact-crc:3EE1127466CC96A3|rigid:XTLpHChYuGANqPV2Fc4WjXyh4T4 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:F1QVN7 uniprotkb:Q29RC0 intact:EBI-9992961|ensembl:ENSDARP00000101727 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 psi-mi:f1qvn7_danre(display_long)|uniprotkb:ift88(gene name)|psi-mi:ift88(display_short) psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:"MI:0813"(proximity ligation assay) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9993118|imex:IM-23508-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005167586.1|ensembl:ENSDARG00000027234(gene)|ensembl:ENSDART00000110943(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007369"(gastrulation)|go:"GO:0019894"(kinesin binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0072019"(proximal convoluted tubule development)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-DRE-5610787|reactome:R-DRE-5620924|reactome:R-DRE-9646399 refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:3C,I|comment:Labeling was greatly reduced or lost when any one protein was not expressed; the exception being for the mutant not expressing cdh23, as some signal remained for Cdh23-Harmonin,Cdh23-Ift88 and Harmonin-Ift88 protein pairs.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:QlsY9Zd04b1DKhN5950Bf3/Ray47955 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 intact-crc:08C75E2D5A6BEFFE|rigid:4DfBNIINF8Fr5MOBzwLhKEZOZ2o false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q6QQE1 uniprotkb:Q29RC0 intact:EBI-9992880 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 psi-mi:q6qqe1_danre(display_long)|uniprotkb:cdh23(gene name)|psi-mi:cdh23(display_short) psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:"MI:0813"(proximity ligation assay) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9993121|imex:IM-23508-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|refseq:NP_999974.1|interpro:IPR033030|go:"GO:0005509"(calcium ion binding)|go:"GO:0005929"(cilium)|go:"GO:0006897"(endocytosis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030030"(cell projection organization)|go:"GO:0032420"(stereocilium)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035678"(neuromast hair cell morphogenesis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050957"(equilibrioception)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules) refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:3A,G, Supp 7|comment:Labeling was greatly reduced or lost when any one protein was not expressed; the exception being for the mutant not expressing cdh23, as some signal remained for Cdh23-Harmonin,Cdh23-Ift88 and Harmonin-Ift88 protein pairs.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:1dvJx7emPY30Fw0IjfhSjl08IO87955 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 intact-crc:79111E0E8F032AD3|rigid:dZYXjv9YSMqU+na4EOtH7GYYaAQ false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:B3DJQ7 uniprotkb:F1QVN7 intact:EBI-9992997 intact:EBI-9992961|ensembl:ENSDARP00000101727 psi-mi:b3djq7_danre(display_long)|uniprotkb:myo7aa(gene name)|psi-mi:myo7aa(display_short)|uniprotkb:myo7a(gene name synonym) psi-mi:f1qvn7_danre(display_long)|uniprotkb:ift88(gene name)|psi-mi:ift88(display_short) psi-mi:"MI:0813"(proximity ligation assay) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9993167|imex:IM-23508-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036961|interpro:IPR041793|interpro:IPR041794|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001452(Src homology-3)|interpro:IPR029071|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR038185|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106 refseq:XP_005167586.1|ensembl:ENSDARG00000027234(gene)|ensembl:ENSDART00000110943(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007369"(gastrulation)|go:"GO:0019894"(kinesin binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0072019"(proximal convoluted tubule development)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-DRE-5610787|reactome:R-DRE-5620924|reactome:R-DRE-9646399 go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:c60HuKi2spSRG8Xfa+A3cSMQJU47955 rogid:QlsY9Zd04b1DKhN5950Bf3/Ray47955 intact-crc:438489555CA174D3|rigid:kF0skwMQ01bhH6dsErHNbeMvng8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:B3DJQ7 uniprotkb:Q6QQE1 intact:EBI-9992997 intact:EBI-9992880 psi-mi:b3djq7_danre(display_long)|uniprotkb:myo7aa(gene name)|psi-mi:myo7aa(display_short)|uniprotkb:myo7a(gene name synonym) psi-mi:q6qqe1_danre(display_long)|uniprotkb:cdh23(gene name)|psi-mi:cdh23(display_short) psi-mi:"MI:0813"(proximity ligation assay) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9993162|imex:IM-23508-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036961|interpro:IPR041793|interpro:IPR041794|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001452(Src homology-3)|interpro:IPR029071|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR038185|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106 interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|refseq:NP_999974.1|interpro:IPR033030|go:"GO:0005509"(calcium ion binding)|go:"GO:0005929"(cilium)|go:"GO:0006897"(endocytosis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030030"(cell projection organization)|go:"GO:0032420"(stereocilium)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035678"(neuromast hair cell morphogenesis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050957"(equilibrioception)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules) go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0044297"(cell body) - - figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:c60HuKi2spSRG8Xfa+A3cSMQJU47955 rogid:1dvJx7emPY30Fw0IjfhSjl08IO87955 intact-crc:0FF6166C7A622547|rigid:fSMrMMc/jMYLw7pfmARLz1xTHdE false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q29RC0 uniprotkb:B3DJQ7 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 intact:EBI-9992997 psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:b3djq7_danre(display_long)|uniprotkb:myo7aa(gene name)|psi-mi:myo7aa(display_short)|uniprotkb:myo7a(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-9993124|imex:IM-23508-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 interpro:IPR036961|interpro:IPR041793|interpro:IPR041794|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001452(Src homology-3)|interpro:IPR029071|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR038185|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106 go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm) - - figure legend:3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 rogid:c60HuKi2spSRG8Xfa+A3cSMQJU47955 intact-crc:F395C1082D68DF18|rigid:jzIkDImz8j39rmE6miZKngCjMew false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q6QQE1 uniprotkb:Q29RC0 intact:EBI-9992880 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 psi-mi:q6qqe1_danre(display_long)|uniprotkb:cdh23(gene name)|psi-mi:cdh23(display_short) psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:"MI:0663"(confocal microscopy) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9992878|imex:IM-23508-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|refseq:NP_999974.1|interpro:IPR033030|go:"GO:0005509"(calcium ion binding)|go:"GO:0005929"(cilium)|go:"GO:0006897"(endocytosis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030030"(cell projection organization)|go:"GO:0032420"(stereocilium)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035678"(neuromast hair cell morphogenesis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050957"(equilibrioception)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules) refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 go:"GO:0044297"(cell body) - - figure legend:1G, S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:1dvJx7emPY30Fw0IjfhSjl08IO87955 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 intact-crc:B1F9A8BC618B84C4|rigid:dZYXjv9YSMqU+na4EOtH7GYYaAQ false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:F1QVN7 uniprotkb:Q29RC0 intact:EBI-9992961|ensembl:ENSDARP00000101727 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 psi-mi:f1qvn7_danre(display_long)|uniprotkb:ift88(gene name)|psi-mi:ift88(display_short) psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:"MI:0663"(confocal microscopy) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9992950|imex:IM-23508-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005167586.1|ensembl:ENSDARG00000027234(gene)|ensembl:ENSDART00000110943(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007369"(gastrulation)|go:"GO:0019894"(kinesin binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0072019"(proximal convoluted tubule development)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097546"(ciliary base)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-DRE-5610787|reactome:R-DRE-5620924|reactome:R-DRE-9646399 refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 go:"GO:0044297"(cell body) - - figure legend:1F, S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:QlsY9Zd04b1DKhN5950Bf3/Ray47955 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 intact-crc:F215647D51CC3FA5|rigid:4DfBNIINF8Fr5MOBzwLhKEZOZ2o false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:B3DJQ7 uniprotkb:Q29RC0 intact:EBI-9992997 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 psi-mi:b3djq7_danre(display_long)|uniprotkb:myo7aa(gene name)|psi-mi:myo7aa(display_short)|uniprotkb:myo7a(gene name synonym) psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:"MI:0663"(confocal microscopy) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9992991|imex:IM-23508-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036961|interpro:IPR041793|interpro:IPR041794|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR000857(Unconventional myosin/plant kinesin-like protein/non-motor protein conserved region MyTH4)|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001452(Src homology-3)|interpro:IPR029071|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007423"(sensory organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR038185|interpro:IPR035963|interpro:IPR036028|interpro:IPR036106 refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 go:"GO:0044297"(cell body) - - figure legend:1H, S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7955(danre-larvae)|taxid:7955(Danio rerio) - 2014/12/01 2014/12/01 rogid:c60HuKi2spSRG8Xfa+A3cSMQJU47955 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 intact-crc:13ECCD34BB4CB66B|rigid:jzIkDImz8j39rmE6miZKngCjMew false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q29RC0 uniprotkb:Q6QQE1 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 intact:EBI-9992880 psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:q6qqe1_danre(display_long)|uniprotkb:cdh23(gene name)|psi-mi:cdh23(display_short) psi-mi:"MI:0663"(confocal microscopy) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9993753|imex:IM-23508-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|refseq:NP_999974.1|interpro:IPR033030|go:"GO:0005509"(calcium ion binding)|go:"GO:0005929"(cilium)|go:"GO:0006897"(endocytosis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030030"(cell projection organization)|go:"GO:0032420"(stereocilium)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035678"(neuromast hair cell morphogenesis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050957"(equilibrioception)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules) - - - figure legend:Supp 10A|comment:"The synCAM2 tag is made up from the signal peptide from human CD33 joined with the extracellular domain of human IGSF4D (Ala 21-Asp 335) fused with a 6X histidine tag at the C-terminus. It functions as a membrane tether for the cdh23 intracellular domain."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2014/12/01 2014/12/02 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 rogid:1dvJx7emPY30Fw0IjfhSjl08IO87955 intact-crc:0E6DBF5E5302E9B2|rigid:dZYXjv9YSMqU+na4EOtH7GYYaAQ false ha tag:c-c tag:n-n|green fluorescent protein tag:c-c|sufficient binding region:3086..3086-3366..3366 - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q29RC0 uniprotkb:Q6QQE1 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 intact:EBI-9992880 psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:q6qqe1_danre(display_long)|uniprotkb:cdh23(gene name)|psi-mi:cdh23(display_short) psi-mi:"MI:0663"(confocal microscopy) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-9993484|imex:IM-23508-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|refseq:NP_999974.1|interpro:IPR033030|go:"GO:0005509"(calcium ion binding)|go:"GO:0005929"(cilium)|go:"GO:0006897"(endocytosis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030030"(cell projection organization)|go:"GO:0032420"(stereocilium)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035678"(neuromast hair cell morphogenesis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050957"(equilibrioception)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules) - - - figure legend:4B|comment:"The intracellular Cdh23 domain, without membrane tethering (the syncam2 tag), did not co-precipitate with Harmonin. (The synCAM2 tag is made up from the signal peptide from human CD33 joined with the extracellular domain of human IGSF4D (Ala 21-Asp 335) fused with a 6X histidine tag at the C-terminus.)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2014/12/01 2014/12/01 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 rogid:1dvJx7emPY30Fw0IjfhSjl08IO87955 intact-crc:AB70B95355B6B2A4|rigid:dZYXjv9YSMqU+na4EOtH7GYYaAQ false ha tag:c-c green fluorescent protein tag:c-c|sufficient binding region:3086..3086-3366..3366|tag:n-n - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q29RC0 uniprotkb:Q6QQE1 intact:EBI-9992907|uniprotkb:E7FD99|ensembl:ENSDARP00000104974 intact:EBI-9992880 psi-mi:q29rc0_danre(display_long)|uniprotkb:ush1c(gene name)|psi-mi:ush1c(display_short) psi-mi:q6qqe1_danre(display_long)|uniprotkb:cdh23(gene name)|psi-mi:cdh23(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Blanco-Sánchez et al. (2014) pubmed:24626987|imex:IM-23508 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9993304|imex:IM-23508-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035018.1|ensembl:ENSDARG00000051876(gene)|ensembl:ENSDART00000121791(transcript)|go:"GO:0001964"(startle response)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032426"(stereocilium tip)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030237|interpro:IPR036034 interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|refseq:NP_999974.1|interpro:IPR033030|go:"GO:0005509"(calcium ion binding)|go:"GO:0005929"(cilium)|go:"GO:0006897"(endocytosis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030030"(cell projection organization)|go:"GO:0032420"(stereocilium)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035678"(neuromast hair cell morphogenesis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0050957"(equilibrioception)|go:"GO:0050974"(detection of mechanical stimulus involved in sensory perception)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules) - - - figure legend:4A|comment:"The intracellular Cdh23 domain, without membrane tethering (the syncam2 tag), did not co-precipitate with Harmonin. (The synCAM2 tag is made up from the signal peptide from human CD33 joined with the extracellular domain of human IGSF4D (Ala 21-Asp 335) fused with a 6X histidine tag at the C-terminus.)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2014/12/01 2014/12/01 rogid:RB0gYsCgMe4PuU6jPPh4K5XQhVg7955 rogid:1dvJx7emPY30Fw0IjfhSjl08IO87955 intact-crc:BB098FA75654CDF2|rigid:dZYXjv9YSMqU+na4EOtH7GYYaAQ false ha tag:c-c sufficient binding region:3086..3086-3366..3366|green fluorescent protein tag:c-c|tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)