#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9Y2D8	uniprotkb:Q15154	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hori et al. (2014)	imex:IM-22217|pubmed:24397932	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9214110|imex:IM-22217-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N	-	-	-	figure legend:sf1h sf3b|comment:Note that hMsd1 binds to γ-tubulin during the whole cell cycle,  whilst binding to PCM1 is not detected during mitosis. hMsd1 appears to interact with  Plk1 in a mitosis specific manner, the mechanism of which remains to be addressed.|comment:"On the other  hand, the hMsd1 mutant lacking the C-terminal half (hMsd1-N, 1–  373 aa) was capable of interacting with PCM1, but not c-tubulin  (Fig 3A and supplementary Fig S3)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/24	2018/04/06	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606	intact-crc:61577BA3EF0E40DE|rigid:6e8dAA/RLYankT7+Nz8AXKbsJfQ	false	binding-associated region:1-373|green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y2D8	uniprotkb:Q15154	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hori et al. (2014)	imex:IM-22217|pubmed:24397932	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9214031|imex:IM-22217-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N	-	-	-	figure legend:F1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/24	2018/04/06	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606	intact-crc:B71481E2409C391B|rigid:lKrENPWm5f4O+5THoIo402AYH/c	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y2D8	uniprotkb:P80162	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-9214033|uniprotkb:B2R4X3|uniprotkb:Q4W5D4|ensembl:ENSP00000226317	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:cxcl6_human(display_long)|uniprotkb:CXCL6(gene name)|psi-mi:CXCL6(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:SCYB6(gene name synonym)|uniprotkb:Chemokine alpha 3(gene name synonym)|uniprotkb:Granulocyte chemotactic protein 2(gene name synonym)|uniprotkb:Small-inducible cytokine B6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hori et al. (2014)	imex:IM-22217|pubmed:24397932	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9214031|imex:IM-22217-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	refseq:NP_002984.1|ensembl:ENSG00000124875(gene)|ensembl:ENST00000226317(transcript)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0008201"(heparin binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032642"(regulation of chemokine production)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045236"(CXCR chemokine receptor binding)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070951"(regulation of neutrophil mediated killing of gram-negative bacterium)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR001089(Small chemokine, C-X-C)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR018048|interpro:IPR033899|interpro:IPR036048|reactome:R-HSA-380108|reactome:R-HSA-418594	-	-	-	figure legend:F1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/24	2018/04/06	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:z0kZUQZ7yjE5mkKOlPF+AuzcQBw9606	intact-crc:B71481E2409C391B|rigid:lKrENPWm5f4O+5THoIo402AYH/c	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y2D8	uniprotkb:Q96CW5	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-1046278|ensembl:ENSP00000261965|uniprotkb:O43631|uniprotkb:O60852|uniprotkb:O60853|uniprotkb:Q7Z4K1|uniprotkb:Q96I79|uniprotkb:Q5T8L2	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:gcp3_human(display_long)|uniprotkb:Spindle pole body protein Spc98 homolog(gene name synonym)|uniprotkb:TUBGCP3(gene name)|psi-mi:TUBGCP3(display_short)|uniprotkb:GCP3(gene name synonym)|uniprotkb:Gamma-ring complex protein 104 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hori et al. (2014)	imex:IM-22217|pubmed:24397932	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9214031|imex:IM-22217-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007338"(single fertilization)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q96CW5|rcsb pdb:6V6B|go:"GO:0000930"(gamma-tubulin complex)|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|ensembl:ENSG00000126216(gene)|ensembl:ENST00000261965(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000923"(equatorial microtubule organizing center)|refseq:NP_006313.1|refseq:NP_001273207.1|refseq:NP_001273208.1|refseq:NP_001273206.1	-	-	-	figure legend:F1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/24	2018/04/06	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:xt+Ngo2s/4djh2PnyMEaxgDyLrs9606	intact-crc:B71481E2409C391B|rigid:lKrENPWm5f4O+5THoIo402AYH/c	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P53350	uniprotkb:Q9Y2D8	intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hori et al. (2014)	imex:IM-22217|pubmed:24397932	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9214117|imex:IM-22217-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	-	-	-	figure legend:sf1h|comment:Note that hMsd1 binds to γ-tubulin during the whole cell cycle,  whilst binding to PCM1 is not detected during mitosis. hMsd1 appears to interact with  Plk1 in a mitosis specific manner, the mechanism of which remains to be addressed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/24	2014/10/16	rogid:fBOK366hV6mDprx9IWhz43gPcJE9606	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:1D0A7FEA5B128FA7|rigid:WCX0fDSdIsOyuhp/qjwF2vXTO4s	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15154	uniprotkb:Q9Y2D8	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Hori et al. (2014)	imex:IM-22217|pubmed:24397932	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9214077|imex:IM-22217-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	go:"GO:0005813"(centrosome)	-	-	figure legend:f1d sf1b|comment:"Immunofluorescence microscopy in both HeLa and U2OS cells  showed that hMsd1/SSX2IP localised to the centrosome and numerous  pericentrosomal foci (Fig 1C and supplementary Fig S1A–C).  The appearance of discrete multiple foci around the centrosome is  reminiscent of centriolar satellites [3]. Indeed, as recently reported  [12], these foci (~70%, n > 500) colocalised with PCM1, the firstmolecule to be identified as a satellite component [3] (Fig 1D and  supplementary Fig S1B and C)."|comment:The same occurs in U2OS cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2014/02/24	2018/04/06	rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	intact-crc:76AD96CBA5271981|rigid:6e8dAA/RLYankT7+Nz8AXKbsJfQ	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9Y2D8	uniprotkb:Q15154	intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279	intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691	psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)	psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Hori et al. (2014)	imex:IM-22217|pubmed:24397932	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9540638|imex:IM-22217-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8	refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N	go:"GO:0005813"(centrosome)	-	-	figure legend:sf1c|comment:"Immunofluorescence microscopy in both HeLa and U2OS cells  showed that hMsd1/SSX2IP localised to the centrosome and numerous  pericentrosomal foci (Fig 1C and supplementary Fig S1A–C).  The appearance of discrete multiple foci around the centrosome is  reminiscent of centriolar satellites [3]. Indeed, as recently reported  [12], these foci (~70%, n > 500) colocalised with PCM1, the firstmolecule to be identified as a satellite component [3] (Fig 1D and  supplementary Fig S1B and C)."|comment:The same occurs in U2OS cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2014/02/24	2018/04/06	rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606	rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606	intact-crc:788D9EC379BFC88A|rigid:6e8dAA/RLYankT7+Nz8AXKbsJfQ	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0422"(immunostaining)