#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:G7P3K6	uniprotkb:F7CYH8	intact:EBI-9844247	intact:EBI-9844295|ensembl:ENSMMUP00000018834	psi-mi:g7p3k6_macfa(display_long)|uniprotkb:EGM_13830(orf name)	psi-mi:f7cyh8_macmu(display_long)|uniprotkb:DRD2(gene name)|psi-mi:DRD2(display_short)|uniprotkb:Dopamine D2 receptor(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Bonaventura et al. (2014)	imex:IM-23232|pubmed:24230991	taxid:9541(macfa)|taxid:9541("Macaca fascicularis (Crab-eating macaque)")	taxid:9544(macmu)|taxid:9544("Macaca mulatta (Rhesus macaque)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844330|imex:IM-23232-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005552444.1|refseq:XP_005552445.1|refseq:XP_005552447.1|interpro:IPR000810(Cannabinoid receptor, type 1)|interpro:IPR002230(Cannabinoid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:"GO:0004949"(cannabinoid receptor activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030426"(growth cone)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0098921"(retrograde trans-synaptic signaling by endocannabinoid)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)	refseq:XP_001085571.1|ensembl:ENSMMUG00000014334(gene)|ensembl:ENSMMUT00000020122(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001591"(dopamine neurotransmitter receptor activity, coupled via Gi/Go)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000929(Dopamine receptor)|interpro:IPR001922(Dopamine D2 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)	-	-	-	figure legend:1,4,5|comment:"The number of positive cells (receptor heteromers) was significantly reduced  in Putamen slices compared with the caudate nucleus."|antagonist:The expression of heteromers was reduced in caudate nucleus slices from l-DOPA treated monkeys  as compared with control and  monkeys with induced  Parkinsons Disease.|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9541(macfa-brain_striatum)|taxid:9541(M. fascicularis striatum)	-	2014/10/10	2014/10/16	rogid:lqrlYa5VAmUZyZnutQlhneY1jLc9541	rogid:4vVcg1TgdSajPi3UFasspUJhyYs9544	intact-crc:B202C36F7B8FB9EA|rigid:iUJ2WClldtf7tZP78WrE2mupaTg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:F7CYH8	uniprotkb:F6X9C0	intact:EBI-9844295|ensembl:ENSMMUP00000018834	intact:EBI-9844264|uniprotkb:G7N3F5|ensembl:ENSMMUP00000000354	psi-mi:f7cyh8_macmu(display_long)|uniprotkb:DRD2(gene name)|psi-mi:DRD2(display_short)|uniprotkb:Dopamine D2 receptor(gene name synonym)	psi-mi:f6x9c0_macmu(display_long)|uniprotkb:ADORA2A(gene name)|psi-mi:ADORA2A(display_short)	psi-mi:"MI:0813"(proximity ligation assay)	Bonaventura et al. (2014)	imex:IM-23232|pubmed:24230991	taxid:9544(macmu)|taxid:9544("Macaca mulatta (Rhesus macaque)")	taxid:9544(macmu)|taxid:9544("Macaca mulatta (Rhesus macaque)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844324|imex:IM-23232-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_001085571.1|ensembl:ENSMMUG00000014334(gene)|ensembl:ENSMMUT00000020122(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001591"(dopamine neurotransmitter receptor activity, coupled via Gi/Go)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000929(Dopamine receptor)|interpro:IPR001922(Dopamine D2 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)	refseq:XP_015005399.1|refseq:XP_015005400.1|refseq:XP_015005401.1|refseq:XP_001095531.1|ensembl:ENSMMUG00000008516(gene)|ensembl:ENSMMUT00000000381(transcript)|go:"GO:0001609"(G protein-coupled adenosine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001513(Adenosine A2A receptor)|interpro:IPR001634(Adenosine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)	-	-	-	figure legend:1,4,5|comment:"The number of positive cells (receptor heteromers) was significantly reduced  in Putamen slices compared with the caudate nucleus."|antagonist:The expression of heteromers was reduced in caudate nucleus slices from l-DOPA treated monkeys  as compared with control and  monkeys with induced  Parkinsons Disease.|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9541(macfa-brain_striatum)|taxid:9541(M. fascicularis striatum)	-	2014/10/10	2014/10/16	rogid:4vVcg1TgdSajPi3UFasspUJhyYs9544	rogid:atDZRWd54Gxs0PwiJ4cvdRkooR89544	intact-crc:04B4C836ADC1E15B|rigid:jL7AtfrjPVS7Ypubl8EMwKn4K8Q	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:F6X9C0	uniprotkb:G7P3K6	intact:EBI-9844264|uniprotkb:G7N3F5|ensembl:ENSMMUP00000000354	intact:EBI-9844247	psi-mi:f6x9c0_macmu(display_long)|uniprotkb:ADORA2A(gene name)|psi-mi:ADORA2A(display_short)	psi-mi:g7p3k6_macfa(display_long)|uniprotkb:EGM_13830(orf name)	psi-mi:"MI:0813"(proximity ligation assay)	Bonaventura et al. (2014)	imex:IM-23232|pubmed:24230991	taxid:9544(macmu)|taxid:9544("Macaca mulatta (Rhesus macaque)")	taxid:9541(macfa)|taxid:9541("Macaca fascicularis (Crab-eating macaque)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9844232|imex:IM-23232-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015005399.1|refseq:XP_015005400.1|refseq:XP_015005401.1|refseq:XP_001095531.1|ensembl:ENSMMUG00000008516(gene)|ensembl:ENSMMUT00000000381(transcript)|go:"GO:0001609"(G protein-coupled adenosine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001513(Adenosine A2A receptor)|interpro:IPR001634(Adenosine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)	refseq:XP_005552444.1|refseq:XP_005552445.1|refseq:XP_005552447.1|interpro:IPR000810(Cannabinoid receptor, type 1)|interpro:IPR002230(Cannabinoid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:"GO:0004949"(cannabinoid receptor activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030426"(growth cone)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0098921"(retrograde trans-synaptic signaling by endocannabinoid)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)	-	-	-	figure legend:1,4,5|comment:"The number of positive cells (receptor heteromers) was significantly reduced  in Putamen slices compared with the caudate nucleus."|antagonist:The expression of heteromers was reduced in caudate nucleus slices from l-DOPA treated monkeys  as compared with control and  monkeys with induced  Parkinsons Disease.|dataset:Affinomics - Interactions curated for the Affinomics consortium.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9541(macfa-brain_striatum)|taxid:9541(M. fascicularis striatum)	-	2014/10/10	2014/10/16	rogid:atDZRWd54Gxs0PwiJ4cvdRkooR89544	rogid:lqrlYa5VAmUZyZnutQlhneY1jLc9541	intact-crc:7EF6CFACC85E825B|rigid:qSMYnxaCNLl0VN1NbixGizxhKek	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)