#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSG00000124766 uniprotkb:P17535 intact:EBI-10044447 intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 psi-mi:sox4_human_gene(display_short)|psi-mi:ENSG00000124766(display_long) psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Higuchi et al. (2013) pubmed:23482931|imex:IM-23573 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10044449|imex:IM-23573-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N - - - figure legend:Fig. 2e|comment:This interaction occurred in activated CD4+ T cells but not in normal resting CD4+ T cells.|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-t cells cd 4+)|taxid:9606(Homo sapiens) - 2014/12/16 2019/01/30 - rogid:npmTGULvlKr4hC8HfmK19GUopf49606 intact-crc:1FEAD583492EC326 false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000124766 uniprotkb:P15408 intact:EBI-10044447 intact:EBI-3893419|uniprotkb:B2RD58|uniprotkb:B3KP27|uniprotkb:B4DYV4|uniprotkb:Q6FG46|ensembl:ENSP00000264716 psi-mi:sox4_human_gene(display_short)|psi-mi:ENSG00000124766(display_long) psi-mi:fosl2_human(display_long)|uniprotkb:FOSL2(gene name)|psi-mi:FOSL2(display_short)|uniprotkb:FRA2(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Higuchi et al. (2013) pubmed:23482931|imex:IM-23573 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10044471|imex:IM-23573-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_016859226.1|refseq:NP_005244.1|dip:DIP-48788N|ensembl:ENSG00000075426(gene)|ensembl:ENST00000264716(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008219"(cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029814 - - - figure legend:Fig. 2e|causality statement:P15408 increases expression at RNA level of ENSG00000124766|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hut102)|taxid:9606(Homo sapiens peripheral blood cutaneous T-cell lymphoma cell line HuT 102) - 2014/12/16 2019/01/30 - rogid:+iPQyqskvPskPMg378TYKhOJ86s9606 intact-crc:A5E56802A4F5D701 false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000124766 uniprotkb:P17535 intact:EBI-10044447 intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 psi-mi:sox4_human_gene(display_short)|psi-mi:ENSG00000124766(display_long) psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Higuchi et al. (2013) pubmed:23482931|imex:IM-23573 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10044477|imex:IM-23573-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N - - - figure legend:Fig. 2e|causality statement:P17535 increases expression at RNA level of ENSG00000124766|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hut102)|taxid:9606(Homo sapiens peripheral blood cutaneous T-cell lymphoma cell line HuT 102) - 2014/12/16 2014/12/16 - rogid:npmTGULvlKr4hC8HfmK19GUopf49606 intact-crc:F38B3C5C35F96103 false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) uniprotkb:P17535 ensembl:ENSG00000124766 intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 intact:EBI-10044447 psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:sox4_human_gene(display_short)|psi-mi:ENSG00000124766(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Higuchi et al. (2013) pubmed:23482931|imex:IM-23573 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10044500|imex:IM-23573-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N - - - - figure legend:Fig. 2e|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-st1)|taxid:9606(Homo sapiens adult T cell lymphoma cell line ST1) - 2014/12/16 2014/12/16 rogid:npmTGULvlKr4hC8HfmK19GUopf49606 - intact-crc:FBCA6A858399AC82 false - binding-associated region:?-? - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr) ensembl:ENSG00000124766 uniprotkb:P15408 intact:EBI-10044447 intact:EBI-3893419|uniprotkb:B2RD58|uniprotkb:B3KP27|uniprotkb:B4DYV4|uniprotkb:Q6FG46|ensembl:ENSP00000264716 psi-mi:sox4_human_gene(display_short)|psi-mi:ENSG00000124766(display_long) psi-mi:fosl2_human(display_long)|uniprotkb:FOSL2(gene name)|psi-mi:FOSL2(display_short)|uniprotkb:FRA2(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Higuchi et al. (2013) pubmed:23482931|imex:IM-23573 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-10044506|imex:IM-23573-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:XP_016859226.1|refseq:NP_005244.1|dip:DIP-48788N|ensembl:ENSG00000075426(gene)|ensembl:ENST00000264716(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008219"(cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029814 - - - figure legend:Fig. 2e|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-st1)|taxid:9606(Homo sapiens adult T cell lymphoma cell line ST1) - 2014/12/16 2014/12/16 - rogid:+iPQyqskvPskPMg378TYKhOJ86s9606 intact-crc:036A9D8A6E2CBC8F false binding-associated region:?-? - - - psi-mi:"MI:1195"(quantitative pcr) psi-mi:"MI:1195"(quantitative pcr)