#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q15075	uniprotkb:Q9H6Y7	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	intact:EBI-1055214|uniprotkb:Q6XYE0|uniprotkb:Q8NDC1|uniprotkb:Q9Y3V1|uniprotkb:D3DTK8|ensembl:ENSP00000262482|ensembl:ENSP00000458794|ensembl:ENSP00000459324|ensembl:ENSP00000460190	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:rn167_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF167(gene name synonym)|uniprotkb:RING finger protein 167(gene name synonym)|uniprotkb:RING105(gene name synonym)|uniprotkb:RNF167(gene name)|psi-mi:RNF167(display_short)|uniprotkb:LP2254(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Yamazaki et al. (2013)	imex:IM-22099|pubmed:23353890	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9101742|imex:IM-22099-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	refseq:NP_056343.1|refseq:NP_001307285.1|refseq:NP_001307286.1|refseq:NP_001307287.1|refseq:NP_001307288.1|refseq:NP_001307289.1|refseq:NP_001307290.1|refseq:NP_001307291.1|refseq:NP_001307292.1|refseq:NP_001307293.1|refseq:NP_001307294.1|ensembl:ENSG00000108523(gene)|ensembl:ENST00000262482(transcript)|ensembl:ENST00000571816(transcript)|ensembl:ENST00000572430(transcript)|ensembl:ENST00000575111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|refseq:XP_016879916.1	go:"GO:0005769"(early endosome)	-	-	figure legend:f6a|comment:"Consistent with this we found that expression of human RNF167 also led to the accumulation of giant endosomes that were positive for EEA1, FK2 and VAMP3, with a concomitant loss of Rab11‐positive recycling endosomes (Figure 6A and B)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/01/13	2014/10/16	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	rogid:IHiUNkyGVw8fPM9DqsAd3JC/eRM9606	intact-crc:533747CCC33D1C73|rigid:Nr4S35ixIcJqXgH2k3jg3owufDI	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q15836	uniprotkb:Q9VI20	intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666	intact:EBI-135970|ensemblmetazoa:FBpp0081217|ensemblmetazoa:FBpp0081218|ensemblmetazoa:FBpp0081219|ensemblmetazoa:FBpp0112110	psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym)	psi-mi:q9vi20_drome(display_long)|uniprotkb:gzl(gene name)|psi-mi:gzl(display_short)|uniprotkb:CG10277-RD(gene name synonym)|uniprotkb:Dmel\CG10277(gene name synonym)|uniprotkb:godzilla(gene name synonym)|uniprotkb:godzilla[CG10277](gene name synonym)|uniprotkb:CG10277(orf name)|uniprotkb:Dmel_CG10277(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Yamazaki et al. (2013)	imex:IM-22099|pubmed:23353890	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9100028|imex:IM-22099-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004772.1|dip:DIP-56422N|ensembl:ENSG00000049245(gene)|ensembl:ENST00000054666(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|ensemblmetazoa:FBgn0037442(gene)|ensemblmetazoa:FBtr0081720(transcript)|ensemblmetazoa:FBtr0081721(transcript)|ensemblmetazoa:FBtr0081722(transcript)|ensemblmetazoa:FBtr0113198(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|flybase:FBgn0037442|refseq:NP_001097695.1|refseq:NP_649653.1|refseq:NP_731079.1|refseq:NP_731080.1	go:"GO:0005768"(endosome)	-	-	figure legend:f5c|comment:"In order to confirm whether VAMP3 is a potential target of Godzilla, we investigated VAMP3 localization in Godzilla‐transfected HEK293 cells. VAMP3 is known to localize on both early and recycling endosomes and is involved in endocytic recycling (McMahon et al, 1993; Galli et al, 1994). In both control and ligase‐dead Godzilla‐transfected cells, VAMP3 displays a similar intracellular distribution, partially overlapping with ligase‐dead Godzilla; suggesting an early and recycling endosome distribution (Figure 5C). In contrast, in cells expressing wild‐type Godzilla VAMP3 is found on enlarged endosomes, where it colocalizes with Godzilla (Figure 5C)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/01/13	2014/10/16	rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606	rogid:7AUkd/GKVLSbWZqpse0Zz5X3Z+87227	intact-crc:48EF781FD3FE83DE|rigid:t77eTV/IzI++ewmu6uX5hHI7qWE	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q06003	uniprotkb:Q15075	intact:EBI-3497279|uniprotkb:Q8T0M7|uniprotkb:Q9W0W3|uniprotkb:E1JGX0|ensemblmetazoa:FBpp0072361	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	psi-mi:goli_drome(display_long)|uniprotkb:gol(gene name)|psi-mi:gol(display_short)|uniprotkb:g1(gene name synonym)|uniprotkb:GL(gene name synonym)|uniprotkb:Protein g1(gene name synonym)|uniprotkb:CG2679(orf name)	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Yamazaki et al. (2013)	imex:IM-22099|pubmed:23353890	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9099973|imex:IM-22099-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001163300.1|refseq:NP_523864.3|refseq:NP_726508.1|flybase:FBgn0004919|refseq:NP_001246517.1|ensemblmetazoa:FBgn0004919(gene)|ensemblmetazoa:FBtr0072459(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-983168	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	go:"GO:0005769"(early endosome)	-	-	figure legend:sf3|comment:"A significant amount of Godzilla clearly colocalizes with endosomal markers, such as EEA1, upon overexpression (Figure 1D; Supplementary Figure S2). While less extensive than that observed with Godzilla, overlap with EEA1 is also observed with the related Goliath (Figures 1D and 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/01/13	2014/10/16	rogid:eSLswqfMmSk+0TwKytRycgI1F807227	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	intact-crc:45406F5BDEB45EA0|rigid:gqRPW5hI8miir3n6H20XGCOnMTk	false	ha tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q15075	uniprotkb:Q9VI20	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	intact:EBI-135970|ensemblmetazoa:FBpp0081217|ensemblmetazoa:FBpp0081218|ensemblmetazoa:FBpp0081219|ensemblmetazoa:FBpp0112110	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:q9vi20_drome(display_long)|uniprotkb:gzl(gene name)|psi-mi:gzl(display_short)|uniprotkb:CG10277-RD(gene name synonym)|uniprotkb:Dmel\CG10277(gene name synonym)|uniprotkb:godzilla(gene name synonym)|uniprotkb:godzilla[CG10277](gene name synonym)|uniprotkb:CG10277(orf name)|uniprotkb:Dmel_CG10277(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Yamazaki et al. (2013)	imex:IM-22099|pubmed:23353890	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9099424|imex:IM-22099-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|ensemblmetazoa:FBgn0037442(gene)|ensemblmetazoa:FBtr0081720(transcript)|ensemblmetazoa:FBtr0081721(transcript)|ensemblmetazoa:FBtr0081722(transcript)|ensemblmetazoa:FBtr0113198(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|flybase:FBgn0037442|refseq:NP_001097695.1|refseq:NP_649653.1|refseq:NP_731079.1|refseq:NP_731080.1	go:"GO:0005769"(early endosome)	-	-	figure legend:f1d f2a|comment:"A significant amount of Godzilla clearly colocalizes with endosomal markers, such as EEA1, upon overexpression (Figure 1D; Supplementary Figure S2). While less extensive than that observed with Godzilla, overlap with EEA1 is also observed with the related Goliath (Figures 1D and 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/01/13	2014/10/16	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	rogid:7AUkd/GKVLSbWZqpse0Zz5X3Z+87227	intact-crc:9158E7F8376D925C|rigid:4OM04gSkkZKFfi9HbD1T9wkJ6ew	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9VI20	uniprotkb:Q15836	intact:EBI-135970|ensemblmetazoa:FBpp0081217|ensemblmetazoa:FBpp0081218|ensemblmetazoa:FBpp0081219|ensemblmetazoa:FBpp0112110	intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666	psi-mi:q9vi20_drome(display_long)|uniprotkb:gzl(gene name)|psi-mi:gzl(display_short)|uniprotkb:CG10277-RD(gene name synonym)|uniprotkb:Dmel\CG10277(gene name synonym)|uniprotkb:godzilla(gene name synonym)|uniprotkb:godzilla[CG10277](gene name synonym)|uniprotkb:CG10277(orf name)|uniprotkb:Dmel_CG10277(orf name)	psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Yamazaki et al. (2013)	imex:IM-22099|pubmed:23353890	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9099981|imex:IM-22099-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|ensemblmetazoa:FBgn0037442(gene)|ensemblmetazoa:FBtr0081720(transcript)|ensemblmetazoa:FBtr0081721(transcript)|ensemblmetazoa:FBtr0081722(transcript)|ensemblmetazoa:FBtr0113198(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|flybase:FBgn0037442|refseq:NP_001097695.1|refseq:NP_649653.1|refseq:NP_731079.1|refseq:NP_731080.1	refseq:NP_004772.1|dip:DIP-56422N|ensembl:ENSG00000049245(gene)|ensembl:ENST00000054666(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034	go:"GO:0005769"(early endosome)|go:"GO:0055037"(recycling endosome)	-	-	figure legend:f5c|comment:"In order to confirm whether VAMP3 is a potential target of Godzilla, we investigated VAMP3 localization in Godzilla‐transfected HEK293 cells. VAMP3 is known to localize on both early and recycling endosomes and is involved in endocytic recycling (McMahon et al, 1993; Galli et al, 1994). In both control and ligase‐dead Godzilla‐transfected cells, VAMP3 displays a similar intracellular distribution, partially overlapping with ligase‐dead Godzilla; suggesting an early and recycling endosome distribution (Figure 5C). In contrast, in cells expressing wild‐type Godzilla VAMP3 is found on enlarged endosomes, where it colocalizes with Godzilla (Figure 5C)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/01/13	2014/10/16	rogid:7AUkd/GKVLSbWZqpse0Zz5X3Z+87227	rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606	intact-crc:7B8B09E467220E6D|rigid:t77eTV/IzI++ewmu6uX5hHI7qWE	false	green fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q15075	uniprotkb:Q06003	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	intact:EBI-3497279|uniprotkb:Q8T0M7|uniprotkb:Q9W0W3|uniprotkb:E1JGX0|ensemblmetazoa:FBpp0072361	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:goli_drome(display_long)|uniprotkb:gol(gene name)|psi-mi:gol(display_short)|uniprotkb:g1(gene name synonym)|uniprotkb:GL(gene name synonym)|uniprotkb:Protein g1(gene name synonym)|uniprotkb:CG2679(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Yamazaki et al. (2013)	imex:IM-22099|pubmed:23353890	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9099432|imex:IM-22099-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	refseq:NP_001163300.1|refseq:NP_523864.3|refseq:NP_726508.1|flybase:FBgn0004919|refseq:NP_001246517.1|ensemblmetazoa:FBgn0004919(gene)|ensemblmetazoa:FBtr0072459(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|reactome:R-DME-5689880|reactome:R-DME-5689896|reactome:R-DME-983168	go:"GO:0005769"(early endosome)	-	-	figure legend:f1d f2a|comment:"A significant amount of Godzilla clearly colocalizes with endosomal markers, such as EEA1, upon overexpression (Figure 1D; Supplementary Figure S2). While less extensive than that observed with Godzilla, overlap with EEA1 is also observed with the related Goliath (Figures 1D and 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/01/13	2014/10/16	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	rogid:eSLswqfMmSk+0TwKytRycgI1F807227	intact-crc:0C6BDA314AC005BE|rigid:gqRPW5hI8miir3n6H20XGCOnMTk	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9VI20	uniprotkb:Q15075	intact:EBI-135970|ensemblmetazoa:FBpp0081217|ensemblmetazoa:FBpp0081218|ensemblmetazoa:FBpp0081219|ensemblmetazoa:FBpp0112110	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	psi-mi:q9vi20_drome(display_long)|uniprotkb:gzl(gene name)|psi-mi:gzl(display_short)|uniprotkb:CG10277-RD(gene name synonym)|uniprotkb:Dmel\CG10277(gene name synonym)|uniprotkb:godzilla(gene name synonym)|uniprotkb:godzilla[CG10277](gene name synonym)|uniprotkb:CG10277(orf name)|uniprotkb:Dmel_CG10277(orf name)	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Yamazaki et al. (2013)	imex:IM-22099|pubmed:23353890	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9099965|imex:IM-22099-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|ensemblmetazoa:FBgn0037442(gene)|ensemblmetazoa:FBtr0081720(transcript)|ensemblmetazoa:FBtr0081721(transcript)|ensemblmetazoa:FBtr0081722(transcript)|ensemblmetazoa:FBtr0113198(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|flybase:FBgn0037442|refseq:NP_001097695.1|refseq:NP_649653.1|refseq:NP_731079.1|refseq:NP_731080.1	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	go:"GO:0005769"(early endosome)	-	-	figure legend:sf3|comment:"A significant amount of Godzilla clearly colocalizes with endosomal markers, such as EEA1, upon overexpression (Figure 1D; Supplementary Figure S2). While less extensive than that observed with Godzilla, overlap with EEA1 is also observed with the related Goliath (Figures 1D and 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2014/01/13	2014/10/16	rogid:7AUkd/GKVLSbWZqpse0Zz5X3Z+87227	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	intact-crc:98EDF8B9298ED8E6|rigid:4OM04gSkkZKFfi9HbD1T9wkJ6ew	false	ha tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9V3I2	uniprotkb:Q9VI20	intact:EBI-150687|ensemblmetazoa:FBpp0077470|ensemblmetazoa:FBpp0077471|ensemblmetazoa:FBpp0077472|ensemblmetazoa:FBpp0077473|ensemblmetazoa:FBpp0077474|ensemblmetazoa:FBpp0077475|ensemblmetazoa:FBpp0303518|ensemblmetazoa:FBpp0303519|ensemblmetazoa:FBpp0303520	intact:EBI-135970|ensemblmetazoa:FBpp0081217|ensemblmetazoa:FBpp0081218|ensemblmetazoa:FBpp0081219|ensemblmetazoa:FBpp0112110	psi-mi:q9v3i2_drome(display_long)|uniprotkb:Rab5(gene name)|psi-mi:Rab5(display_short)|uniprotkb:Drab5(gene name synonym)|uniprotkb:AAF51265(gene name synonym)|uniprotkb:BAA88244(gene name synonym)|uniprotkb:DRab5(gene name synonym)|uniprotkb:Dm Rab5(gene name synonym)|uniprotkb:DmRab5(gene name synonym)|uniprotkb:Dmel\CG3664(gene name synonym)|uniprotkb:RAB5(gene name synonym)|uniprotkb:RAB5a(gene name synonym)|uniprotkb:Rab(gene name synonym)|uniprotkb:Rab-5(gene name synonym)|uniprotkb:dRab5(gene name synonym)|uniprotkb:drab5(gene name synonym)|uniprotkb:"l(2)k08232"(gene name synonym)|uniprotkb:rab5(gene name synonym)|uniprotkb:Dmel_CG3664(orf name)|uniprotkb:CG3664(orf name)	psi-mi:q9vi20_drome(display_long)|uniprotkb:gzl(gene name)|psi-mi:gzl(display_short)|uniprotkb:CG10277-RD(gene name synonym)|uniprotkb:Dmel\CG10277(gene name synonym)|uniprotkb:godzilla(gene name synonym)|uniprotkb:godzilla[CG10277](gene name synonym)|uniprotkb:CG10277(orf name)|uniprotkb:Dmel_CG10277(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Yamazaki et al. (2013)	imex:IM-22099|pubmed:23353890	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9099955|imex:IM-22099-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523457.1|refseq:NP_722795.1|refseq:NP_722796.1|refseq:NP_722797.1|refseq:NP_722798.1|refseq:NP_722799.1|flybase:FBgn0014010|refseq:NP_001259925.1|refseq:NP_001259926.1|refseq:NP_001259927.1|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0035220"(wing disc development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048477"(oogenesis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048675"(axon extension)|go:"GO:0048803"(imaginal disc-derived male genitalia morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0061883"(clathrin-dependent endocytosis involved in vitellogenesis)|go:"GO:0098793"(presynapse)|go:"GO:0099532"(synaptic vesicle endosomal processing)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-432722|reactome:R-DME-6798695|reactome:R-DME-8854214|reactome:R-DME-8856828|reactome:R-DME-8873719|reactome:R-DME-8876198|reactome:R-DME-983231|go:"GO:0007349"(cellularization)|ensemblmetazoa:FBgn0014010(gene)|ensemblmetazoa:FBtr0077793(transcript)|ensemblmetazoa:FBtr0077794(transcript)|ensemblmetazoa:FBtr0077795(transcript)|ensemblmetazoa:FBtr0077796(transcript)|ensemblmetazoa:FBtr0077797(transcript)|ensemblmetazoa:FBtr0077798(transcript)|ensemblmetazoa:FBtr0330668(transcript)|ensemblmetazoa:FBtr0330669(transcript)|ensemblmetazoa:FBtr0330670(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0007298"(border follicle cell migration)	interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003137(Protease-associated PA)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044744|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|ensemblmetazoa:FBgn0037442(gene)|ensemblmetazoa:FBtr0081720(transcript)|ensemblmetazoa:FBtr0081721(transcript)|ensemblmetazoa:FBtr0081722(transcript)|ensemblmetazoa:FBtr0113198(transcript)|go:"GO:0005768"(endosome)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|flybase:FBgn0037442|refseq:NP_001097695.1|refseq:NP_649653.1|refseq:NP_731079.1|refseq:NP_731080.1	go:"GO:0005768"(endosome)	-	-	figure legend:f1e sf1e-g|comment:"in agreement with these results, endogenous Godzilla protein in Drosophila tissues displays a vesicle localization overlapping with endosomes (Supplementary Figure S1E–G). To confirm the presence of endogenous Godzilla protein in the endosomal compartment, we expressed activated Rab5—Rab5Q88LYFP (Stenmark et al, 1994) to produce enlarged endosomes in a number of tissues. Expression of activated Rab5–Rab5Q88LYFP in the wing disc leads to the accumulation of endogenous Godzilla protein on the resulting enlarged endosomes (Figure 1E)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-wing disc)|taxid:7227(Drosophila melanogaster wing disc)	-	2014/01/13	2014/10/16	rogid:wTcCiL+f9QaG1AiHXhGX8PXHwr47227	rogid:7AUkd/GKVLSbWZqpse0Zz5X3Z+87227	intact-crc:7928A93F425E0B6E|rigid:fAa82gdjp94/T37sMh7jFFV8X+I	false	yellow fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0422"(immunostaining)