#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
ensembl:ENSG00000105398	uniprotkb:P35398	intact:EBI-9874505	intact:EBI-748689|uniprotkb:P45445|uniprotkb:Q96H83|uniprotkb:P35397|uniprotkb:P35399|uniprotkb:Q495X4|ensembl:ENSP00000335087	psi-mi:st2a1_human_gene(display_short)|psi-mi:ENSG00000105398(display_long)	psi-mi:rora_human(display_long)|uniprotkb:Retinoid-related orphan receptor-alpha(gene name synonym)|uniprotkb:Nuclear receptor RZR-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 1(gene name synonym)|uniprotkb:RORA(gene name)|psi-mi:RORA(display_short)|uniprotkb:NR1F1(gene name synonym)|uniprotkb:RZRA(gene name synonym)|uniprotkb:RAR-related orphan receptor A(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Ou et al. (2013)	imex:IM-23249|pubmed:23211525	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9874507|imex:IM-23249-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002934.1|refseq:NP_599022.1|refseq:NP_599023.1|refseq:NP_599024.1|ensembl:ENSG00000069667(gene)|ensembl:ENST00000335670(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046068"(cGMP metabolic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|rcsb pdb:1N83|rcsb pdb:1S0X|rcsb pdb:4S15|reactome:R-HSA-1368082|reactome:R-HSA-1989781|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-6785807|reactome:R-HSA-9707616|dip:DIP-29938N	-	-	-	figure legend:Fig. 3a|causality statement:P35398 increases expression at RNA level of ENSG00000105398|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2014/10/29	2019/01/30	-	rogid:T0D9Nky64l6I78rJh0EL459qKk49606	intact-crc:46747F4F0021CF1D	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000105398	uniprotkb:P51449	intact:EBI-9874505	intact:EBI-3908771|uniprotkb:Q8NCY8|uniprotkb:Q5SZR9|uniprotkb:Q8N5V7|ensembl:ENSP00000327025	psi-mi:st2a1_human_gene(display_short)|psi-mi:ENSG00000105398(display_long)	psi-mi:rorg_human(display_long)|uniprotkb:RORC(gene name)|psi-mi:RORC(display_short)|uniprotkb:NR1F3(gene name synonym)|uniprotkb:RORG(gene name synonym)|uniprotkb:RZRG(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Ou et al. (2013)	imex:IM-23249|pubmed:23211525	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9874513|imex:IM-23249-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001001523.1|refseq:NP_005051.2|dip:DIP-60622N|ensembl:ENST00000318247(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048535"(lymph node development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101|rcsb pdb:3B0W|rcsb pdb:3KYT|rcsb pdb:3L0J|rcsb pdb:3L0L|rcsb pdb:4NB6|rcsb pdb:4NIE|rcsb pdb:4QM0|rcsb pdb:4S14|rcsb pdb:4WLB|rcsb pdb:4WPF|rcsb pdb:4WQP|rcsb pdb:4XT9|rcsb pdb:4YMQ|rcsb pdb:4YPQ|rcsb pdb:4ZJR|rcsb pdb:4ZJW|rcsb pdb:4ZOM|rcsb pdb:5APH|rcsb pdb:5APJ|rcsb pdb:5APK|rcsb pdb:5AYG|rcsb pdb:5C4O|rcsb pdb:5C4S|rcsb pdb:5C4T|rcsb pdb:5C4U|rcsb pdb:5EJV|rcsb pdb:5ETH|rcsb pdb:5G42|rcsb pdb:5G43|rcsb pdb:5G44|rcsb pdb:5G45|rcsb pdb:5G46|rcsb pdb:5IXK|rcsb pdb:5IZ0|rcsb pdb:5K38|rcsb pdb:5K3L|ensembl:ENSG00000143365(gene)|rcsb pdb:5K3M|rcsb pdb:5K3N|rcsb pdb:5K6E|rcsb pdb:5K74|rcsb pdb:5LWP|rcsb pdb:5M96|rcsb pdb:5NI5|rcsb pdb:5NI7|rcsb pdb:5NI8|rcsb pdb:5NIB|rcsb pdb:5NTI|rcsb pdb:5NTK|rcsb pdb:5NTN|rcsb pdb:5NTP|rcsb pdb:5NTQ|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:5UFO|rcsb pdb:5UFR|rcsb pdb:5UHI|rcsb pdb:5VB3|rcsb pdb:5VB5|rcsb pdb:5VB6|rcsb pdb:5VB7|rcsb pdb:5VQK|rcsb pdb:5VQL|rcsb pdb:5W4R|rcsb pdb:5W4V|rcsb pdb:5X8Q|rcsb pdb:5YP5|rcsb pdb:5YP6|rcsb pdb:5ZA1|rcsb pdb:6A22|rcsb pdb:6B30|rcsb pdb:6B31|rcsb pdb:6B33|rcsb pdb:6BN6|rcsb pdb:6BR2|rcsb pdb:6BR3|rcsb pdb:6CN5|rcsb pdb:6CN6|rcsb pdb:6CVH|rcsb pdb:6E3E|rcsb pdb:6E3G|rcsb pdb:6ESN|rcsb pdb:6FGQ|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|rcsb pdb:6IVX|rcsb pdb:6J1L|rcsb pdb:6J3N|rcsb pdb:6LO9|rcsb pdb:6LOA|rcsb pdb:6LOB|rcsb pdb:6LOC|rcsb pdb:6NAD|rcsb pdb:6NWS|rcsb pdb:6NWT|rcsb pdb:6NWU|rcsb pdb:6O3Z|rcsb pdb:6O98|rcsb pdb:6P9F|rcsb pdb:6Q2W|rcsb pdb:6Q6M|rcsb pdb:6Q6O|rcsb pdb:6Q7A|rcsb pdb:6Q7H|rcsb pdb:6R7A|rcsb pdb:6R7J|rcsb pdb:6R7K|rcsb pdb:6SAL|rcsb pdb:6SLZ|rcsb pdb:6T4G|rcsb pdb:6T4I|rcsb pdb:6T4J|rcsb pdb:6T4K|rcsb pdb:6T4T|rcsb pdb:6T4U|rcsb pdb:6T4W|rcsb pdb:6T4X|rcsb pdb:6T4Y|rcsb pdb:6T50|rcsb pdb:6TLM|rcsb pdb:6TLQ|rcsb pdb:6TLT|rcsb pdb:6U25|rcsb pdb:6UCG|rcsb pdb:6VQF|rcsb pdb:6VSW|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XAE|rcsb pdb:6XFV|rcsb pdb:7JH2|rcsb pdb:7JTM|rcsb pdb:7JYM|rcsb pdb:7KCO|rcsb pdb:7KQJ|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|rcsb pdb:7LUK|rcsb pdb:7NEC|rcsb pdb:7NP5|rcsb pdb:7NP6|rcsb pdb:7NPC|reactome:R-HSA-383280|reactome:R-HSA-6785807|reactome:R-HSA-8949275	-	-	-	figure legend:Fig. 3a|causality statement:P51449 increases expression at RNA level of ENSG00000105398|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2014/10/29	2019/01/30	-	rogid:qkQ5csU6qSSESXrjWjdZ4zthECU9606	intact-crc:53CEF5F701EC3B39	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q14994	ensembl:ENSG00000105398	intact:EBI-960794|uniprotkb:E9PB75|uniprotkb:E9PC13|uniprotkb:E9PDU3|uniprotkb:E9PHC8|uniprotkb:Q6GZ76|uniprotkb:Q6GZ79|uniprotkb:Q6GZ82|uniprotkb:Q6GZ89|uniprotkb:E9PGH6|uniprotkb:E9PH10|uniprotkb:Q5VTW5|uniprotkb:Q5VTW6|uniprotkb:E9PHN4|uniprotkb:Q6GZ77|uniprotkb:Q6GZ78|uniprotkb:Q6GZ83|uniprotkb:F1D8Q0|uniprotkb:F1D8Q1|uniprotkb:Q0VAC9|uniprotkb:Q6GZ68|uniprotkb:Q6GZ84|uniprotkb:Q6GZ87|uniprotkb:Q6GZ85|uniprotkb:Q4U0F0|ensembl:ENSP00000356961	intact:EBI-9874505	psi-mi:nr1i3_human(display_long)|uniprotkb:NR1I3(gene name)|psi-mi:NR1I3(display_short)|uniprotkb:CAR(gene name synonym)|uniprotkb:Constitutive androstane receptor(gene name synonym)|uniprotkb:Constitutive activator of retinoid response(gene name synonym)|uniprotkb:Orphan nuclear receptor MB67(gene name synonym)	psi-mi:st2a1_human_gene(display_short)|psi-mi:ENSG00000105398(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Ou et al. (2013)	imex:IM-23249|pubmed:23211525	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9874519|imex:IM-23249-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001070941.1|refseq:NP_001070944.1|refseq:NP_001070945.1|refseq:NP_001070948.1|refseq:NP_005113.1|refseq:NP_001070937.1|refseq:NP_001070942.1|refseq:NP_001070943.1|refseq:NP_001070946.1|refseq:NP_001070938.1|refseq:NP_001070940.1|refseq:NP_001070947.1|refseq:NP_001070949.1|refseq:NP_001070950.1|refseq:NP_001070939.1|ensembl:ENSG00000143257(gene)|ensembl:ENST00000367982(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1XV9|rcsb pdb:1XVP|reactome:R-HSA-383280	-	-	-	-	figure legend:Fig. 3a|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2014/10/29	2019/01/30	rogid:O7jzKsV+T6ebbQQTaZq0xYiqls89606	-	intact-crc:47A46DDB420E7EAD	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)