#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-9976699	uniprotkb:P17676	-	intact:EBI-969696|intact:EBI-28973829|ensembl:ENSP00000305422|uniprotkb:Q96IH2|uniprotkb:Q9H4Z5|uniprotkb:A8K671	psi-mi:csn5_human_cebp-site_dna-probe(display_short)|psi-mi:EBI-9976699(display_long)	psi-mi:cebpb_human(display_long)|uniprotkb:CEBPB(gene name)|psi-mi:CEBPB(display_short)|uniprotkb:TCF5(gene name synonym)|uniprotkb:PP9092(orf name)|uniprotkb:Liver activator protein(gene name synonym)|uniprotkb:Nuclear factor NF-IL6(gene name synonym)|uniprotkb:Transcription factor 5(gene name synonym)|uniprotkb:Liver-enriched inhibitory protein(gene name synonym)	psi-mi:"MI:0412"(electrophoretic mobility supershift assay)	Shackleford et al. (2011)	pubmed:21689417|imex:IM-23293	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9976973|imex:IM-23293-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000121022(see-also)	refseq:NP_001272807.1|refseq:NP_001272808.1|ensembl:ENSG00000172216(gene)|ensembl:ENST00000303004(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002432"(granuloma formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006953"(acute-phase response)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007613"(memory)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0097421"(liver regeneration)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901329"(regulation of odontoblast differentiation)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P17676|rcsb pdb:1GTW|rcsb pdb:1GU4|rcsb pdb:1GU5|rcsb pdb:1H88|rcsb pdb:1H89|rcsb pdb:1H8A|rcsb pdb:1HJB|rcsb pdb:1IO4|rcsb pdb:2E42|rcsb pdb:2E43|rcsb pdb:6MG1|rcsb pdb:6MG2|rcsb pdb:6MG3|reactome:R-HSA-2559582|reactome:R-HSA-380994|reactome:R-HSA-381340|reactome:R-HSA-8853884|reactome:R-HSA-9616222|reactome:R-HSA-9633012|reactome:R-HSA-9648895|ensembl:ENSP00000305422|refseq:NP_005185.2|dip:DIP-35345N	-	-	-	figure legend:Fig. 3c|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/17	2019/01/30	-	rogid:RZKdnZRt48VZoER/NDVHSDFzqEA9606	intact-crc:30800987F1BCF830	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P15976	intact:EBI-9976970	intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858	-	psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym)	psi-mi:csn5_human_gata-site_dna-probe(display_short)|psi-mi:EBI-9976970(display_long)	psi-mi:"MI:0412"(electrophoretic mobility supershift assay)	Shackleford et al. (2011)	pubmed:21689417|imex:IM-23293	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9976991|imex:IM-23293-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N	ensembl:ENSG00000121022(see-also)	-	-	-	figure legend:Fig. 3c|caution:The sequence of the GATA-binding site probe in Fig. 3b is different from the one shown in Table 1, and neither of them matches the GATA1 site in the Jab1 promoter sequence shown in Fig. 1b. The sequence of the probe participating in this interaction was based on the GATA1 site in Fig. 1b.|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/11/17	2019/01/30	rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606	-	intact-crc:54948325C74D393D	false	-	32p radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P49715	ensembl:ENSG00000121022	intact:EBI-1172054|uniprotkb:A7LNP2|uniprotkb:Q05CA4|uniprotkb:P78319|ensembl:ENSP00000427514	intact:EBI-9977027	psi-mi:cebpa_human(display_long)|uniprotkb:CEBPA(gene name)|psi-mi:CEBPA(display_short)|uniprotkb:CEBP(gene name synonym)	psi-mi:csn5_human_gene(display_short)|psi-mi:ENSG00000121022(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Shackleford et al. (2011)	pubmed:21689417|imex:IM-23293	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9977029|imex:IM-23293-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENSG00000245848(gene)|ensembl:ENST00000498907(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048469"(cell maturation)|go:"GO:0048839"(inner ear development)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P49715|rcsb pdb:6DC0|reactome:R-HSA-381340|reactome:R-HSA-9616222|refseq:NP_004355.2|refseq:NP_001272758.1|refseq:NP_001274353.1|refseq:NP_001274364.1|dip:DIP-37882N	-	-	-	-	figure legend:Fig. 4d|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2014/11/17	2019/01/30	rogid:uo2VMV1hbdAvsRxr6yU2EVW11nY9606	-	intact-crc:7488084D086C3ACC	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000121022	uniprotkb:P17676	intact:EBI-9977027	intact:EBI-969696|intact:EBI-28973829|ensembl:ENSP00000305422|uniprotkb:Q96IH2|uniprotkb:Q9H4Z5|uniprotkb:A8K671	psi-mi:csn5_human_gene(display_short)|psi-mi:ENSG00000121022(display_long)	psi-mi:cebpb_human(display_long)|uniprotkb:CEBPB(gene name)|psi-mi:CEBPB(display_short)|uniprotkb:TCF5(gene name synonym)|uniprotkb:PP9092(orf name)|uniprotkb:Liver activator protein(gene name synonym)|uniprotkb:Nuclear factor NF-IL6(gene name synonym)|uniprotkb:Transcription factor 5(gene name synonym)|uniprotkb:Liver-enriched inhibitory protein(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Shackleford et al. (2011)	pubmed:21689417|imex:IM-23293	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9977035|imex:IM-23293-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001272807.1|refseq:NP_001272808.1|ensembl:ENSG00000172216(gene)|ensembl:ENST00000303004(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002432"(granuloma formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006953"(acute-phase response)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007613"(memory)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0097421"(liver regeneration)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901329"(regulation of odontoblast differentiation)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P17676|rcsb pdb:1GTW|rcsb pdb:1GU4|rcsb pdb:1GU5|rcsb pdb:1H88|rcsb pdb:1H89|rcsb pdb:1H8A|rcsb pdb:1HJB|rcsb pdb:1IO4|rcsb pdb:2E42|rcsb pdb:2E43|rcsb pdb:6MG1|rcsb pdb:6MG2|rcsb pdb:6MG3|reactome:R-HSA-2559582|reactome:R-HSA-380994|reactome:R-HSA-381340|reactome:R-HSA-8853884|reactome:R-HSA-9616222|reactome:R-HSA-9633012|reactome:R-HSA-9648895|ensembl:ENSP00000305422|refseq:NP_005185.2|dip:DIP-35345N	-	-	-	figure legend:Fig. 4d|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2014/11/17	2019/01/30	-	rogid:RZKdnZRt48VZoER/NDVHSDFzqEA9606	intact-crc:A3198EAA7DC52515	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000121022	uniprotkb:P15976	intact:EBI-9977027	intact:EBI-3909284|uniprotkb:Q96GB8|ensembl:ENSP00000365858	psi-mi:csn5_human_gene(display_short)|psi-mi:ENSG00000121022(display_long)	psi-mi:gata1_human(display_long)|uniprotkb:GATA1(gene name)|psi-mi:GATA1(display_short)|uniprotkb:ERYF1(gene name synonym)|uniprotkb:GF1(gene name synonym)|uniprotkb:Eryf1(gene name synonym)|uniprotkb:GATA-binding factor 1(gene name synonym)|uniprotkb:NF-E1 DNA-binding protein(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Shackleford et al. (2011)	pubmed:21689417|imex:IM-23293	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9977041|imex:IM-23293-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_002040.1|ensembl:ENSG00000102145(gene)|ensembl:ENST00000376670(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0010559"(regulation of glycoprotein biosynthetic process)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0010725"(regulation of primitive erythrocyte differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030221"(basophil differentiation)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035854"(eosinophil fate commitment)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0097028"(dendritic cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR029524|interpro:IPR039355|mint:P15976|rcsb pdb:6G0Q|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-983231|dip:DIP-41431N	-	-	-	figure legend:Fig. 4d|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2014/11/17	2019/01/30	-	rogid:Y/36ySlvsXrGtNSXa4y3Vl7iaJk9606	intact-crc:7FF39DD697D52B33	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000121022	uniprotkb:P40763	intact:EBI-9977027	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3	psi-mi:csn5_human_gene(display_short)|psi-mi:ENSG00000121022(display_long)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Shackleford et al. (2011)	pubmed:21689417|imex:IM-23293	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-9977057|imex:IM-23293-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N	-	-	crc64:6C00632211C8012D	figure legend:Fig. 5c|stimulant:P21272-2|comment:"More CSN5/JAB1 promoter DNA co-precipitated with anti-Stat3 antibody from cells transfected with Rat C/EBP-beta2 (P21272-2) compared to cells transfected with empty control vector."|causality statement:P40763 increases expression at RNA level of ENSG00000121022|causality statement:P40763 increases expression at protein level of ENSG00000121022|causality statement:P21272-2 increases binding of P40763 to ENSG00000121022|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma)	-	2014/11/17	2019/01/30	-	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	intact-crc:9A10792256E19A82	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)