#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75161 uniprotkb:Q68CZ1-2 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-9356215|ensembl:ENSP00000262135 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9356324|imex:IM-22582-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) go:"GO:0005813"(centrosome) - isoform-comment:No experimental confirmation available. figure legend:3e, Supplement. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2014/04/10 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 intact-crc:82F0666985574A25|rigid:maDoEuXnHhbtHYXKR05nqX4ozvo false enhanced green fluorescent protein tag:n-n sufficient binding region:591-1235|red fluorescent protein tag:n-n - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:O75161 uniprotkb:Q68CZ1-2 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-9356215|ensembl:ENSP00000262135 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9356484|imex:IM-22582-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) omim:606966(see-also)|omim:611560(see-also) - isoform-comment:No experimental confirmation available. figure legend:S6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/04/10 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 intact-crc:36B7CEC947534E56|rigid:maDoEuXnHhbtHYXKR05nqX4ozvo false sufficient binding region:591-1093 mutation decreasing interaction:615-615(611560)|necessary binding region:684-1235 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68CZ1-2 uniprotkb:O75161 intact:EBI-9356215|ensembl:ENSP00000262135 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9526725|imex:IM-22582-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 omim:606966(see-also)|omim:611560(see-also) isoform-comment:No experimental confirmation available. - figure legend:S6b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/04/10 2014/10/16 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 intact-crc:9127156234551600|rigid:maDoEuXnHhbtHYXKR05nqX4ozvo false necessary binding region:684-1235|mutation decreasing interaction:615-615(611560) sufficient binding region:591-1093 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68CZ1-2 uniprotkb:O75161 intact:EBI-9356215|ensembl:ENSP00000262135 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9356294|imex:IM-22582-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 omim:606966(see-also)|omim:611560(see-also) isoform-comment:No experimental confirmation available. - figure legend:2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/04/10 2014/10/16 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 intact-crc:A9E38158CD9CF90D|rigid:maDoEuXnHhbtHYXKR05nqX4ozvo false sufficient binding region:771-926 mutation decreasing interaction:754-754(606966)|necessary binding region:779-1093 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q68CZ1-2 uniprotkb:Q68CZ1-2 intact:EBI-9356215|ensembl:ENSP00000262135 intact:EBI-9356215|ensembl:ENSP00000262135 psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9356239|imex:IM-22582-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/10 2014/10/16 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 intact-crc:86D02086487013F2|rigid:eZJKjGMNAUfimp//UPk0g4EKCM4 false glutathione s tranferase tag:n-n|sufficient binding region:771-926 flag tag:n-n|sufficient binding region:591-1235 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q68CZ1-2 uniprotkb:O75161 intact:EBI-9356215|ensembl:ENSP00000262135 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:"MI:0096"(pull down) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9356227|imex:IM-22582-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 - isoform-comment:No experimental confirmation available. - figure legend:2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/10 2014/10/16 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 intact-crc:F887C4D13100D691|rigid:maDoEuXnHhbtHYXKR05nqX4ozvo false glutathione s tranferase tag:n-n|sufficient binding region:771-926 flag tag:?-?|sufficient binding region:591-1093 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75161 uniprotkb:Q68CZ1-2 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-9356215|ensembl:ENSP00000262135 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9356564|imex:IM-22582-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) - - isoform-comment:No experimental confirmation available. figure legend:S1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/04/10 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 intact-crc:3D240466699FAE9E|rigid:maDoEuXnHhbtHYXKR05nqX4ozvo false glutathione s tranferase tag:?-?|sufficient binding region:591-1093 sufficient binding region:771-926|flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75161 uniprotkb:Q68CZ1-2 intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0 intact:EBI-9356215|ensembl:ENSP00000262135 psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym) psi-mi:q68cz1-2(display_long)|uniprotkb:RPGRIP1L(gene name)|psi-mi:RPGRIP1L(display_short)|uniprotkb:FTM(gene name synonym)|uniprotkb:KIAA1005(gene name synonym)|uniprotkb:NPHP8(gene name synonym)|uniprotkb:Nephrocystin-8(gene name synonym)|uniprotkb:RPGR-interacting protein 1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9356262|imex:IM-22582-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1 intact:EBI-5235485(isoform-parent)|ensembl:ENSG00000103494(gene)|ensembl:ENST00000262135(transcript) - - isoform-comment:No experimental confirmation available. figure legend:2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2014/04/10 2014/10/16 rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606 rogid:x7LFks08Dro4OL3bI9rtRufu+xI9606 intact-crc:6B8D873EEB4A0B44|rigid:maDoEuXnHhbtHYXKR05nqX4ozvo false ha tag:n-n flag tag:n-n|sufficient binding region:591-1235 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q32Q04 uniprotkb:D3Z8G3 intact:EBI-9527028 intact:EBI-9526991|ensembl:ENSRNOP00000015876 psi-mi:q32q04_rat(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short) psi-mi:d3z8g3_rat(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:RGD1311099_predicted(gene name synonym)|uniprotkb:rCG_44299(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9527026|imex:IM-22582-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029775|go:"GO:0005856"(cytoskeleton)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097730"(non-motile cilium) refseq:XP_017456772.1|rgd:1311099|refseq:NP_001100884.1|ensembl:ENSRNOG00000011829(gene)|ensembl:ENSRNOT00000015876(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-RNO-5610787|reactome:R-RNO-5620912 - - - figure legend:Supplement. 5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-retina)|taxid:10116(Rattus norvegicus) - 2014/04/10 2014/10/16 rogid:dO9JB0K+8qXnCOAHsh7qpWDHe7810116 rogid:4HxxvS2MTZz8ztnHbyt0WfhnxK810116 intact-crc:CBF9039A072ABB30|rigid:anv83Lsl/RIGcOyzNvvdckkLNms false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:D3Z8G3 uniprotkb:Q32Q04 intact:EBI-9526991|ensembl:ENSRNOP00000015876 intact:EBI-9527028 psi-mi:d3z8g3_rat(display_long)|uniprotkb:Rpgrip1l(gene name)|psi-mi:Rpgrip1l(display_short)|uniprotkb:RGD1311099_predicted(gene name synonym)|uniprotkb:rCG_44299(orf name) psi-mi:q32q04_rat(display_long)|uniprotkb:Nphp4(gene name)|psi-mi:Nphp4(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Arts et al. (2007) pubmed:17558407|imex:IM-22582 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-9527046|imex:IM-22582-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017456772.1|rgd:1311099|refseq:NP_001100884.1|ensembl:ENSRNOG00000011829(gene)|ensembl:ENSRNOT00000015876(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005879"(axonemal microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0031870"(thromboxane A2 receptor binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043584"(nose development)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0060039"(pericardium development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0090102"(cochlea development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031136|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|reactome:R-RNO-5610787|reactome:R-RNO-5620912 interpro:IPR029775|go:"GO:0005856"(cytoskeleton)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097730"(non-motile cilium) go:"GO:0036064"(ciliary basal body) - - figure legend:5o|comment:Colocalization in renal tubules|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-kidney)|taxid:10116(Rat kidney) - 2014/04/10 2014/10/16 rogid:4HxxvS2MTZz8ztnHbyt0WfhnxK810116 rogid:dO9JB0K+8qXnCOAHsh7qpWDHe7810116 intact-crc:C08E1BF8808053F3|rigid:anv83Lsl/RIGcOyzNvvdckkLNms false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)