#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0C045 uniprotkb:Q9UHV9 intact:EBI-9351969 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:f_hcv77(display_long)|uniprotkb:Alternate reading frame protein/F-protein(gene name synonym)|uniprotkb:Frameshifted protein(gene name synonym)|uniprotkb:p16(gene name synonym)|uniprotkb:p17(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Tsao et al. (2006) imex:IM-23812|pubmed:16876117 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:1335"(HPIDb) intact:EBI-10685314|imex:IM-23812-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002522(Hepatitis C virus capsid protein)|go:"GO:0001848"(complement binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035375"(zymogen binding)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0051494"(negative regulation of cytoskeleton organization)|go:"GO:0097655"(serpin family protein binding) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N go:"GO:0042025"(host cell nucleus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm) - - figure legend:2B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2014/04/13 2015/02/25 rogid:UBoCmCg80GlVxpcs3q93gqjcUGk63746 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 intact-crc:16835D27B06E7187|rigid:J+rYG2iuOF3YLwrdM52L3gtribY false green fluorescent protein tag:n-n v5 tag:c-c - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9UHV9 uniprotkb:O60925 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 intact:EBI-356919|uniprotkb:Q53F95|uniprotkb:Q96EX6|uniprotkb:B2RD02|ensembl:ENSP00000261813 psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:pfd1_human(display_long)|uniprotkb:PFDN1(gene name)|psi-mi:PFDN1(display_short)|uniprotkb:PFD1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsao et al. (2006) imex:IM-23812|pubmed:16876117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10685333|imex:IM-23812-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N refseq:NP_002613.2|ensembl:ENSG00000113068(gene)|ensembl:ENST00000261813(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O60925|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - - figure legend:3B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/04/13 2015/02/25 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 rogid:repqo0hQgD7XgRAZll8ucK2jwz49606 intact-crc:EA125172FCC84EFE|rigid:Nx7VxHGscLRewIuh9jZhIYosteE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHV9 uniprotkb:P0C045 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 intact:EBI-9351969 psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:f_hcv77(display_long)|uniprotkb:Alternate reading frame protein/F-protein(gene name synonym)|uniprotkb:Frameshifted protein(gene name synonym)|uniprotkb:p16(gene name synonym)|uniprotkb:p17(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsao et al. (2006) imex:IM-23812|pubmed:16876117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10685333|imex:IM-23812-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N interpro:IPR002522(Hepatitis C virus capsid protein)|go:"GO:0001848"(complement binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035375"(zymogen binding)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0051494"(negative regulation of cytoskeleton organization)|go:"GO:0097655"(serpin family protein binding) - - - figure legend:3B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/04/13 2015/02/25 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 rogid:UBoCmCg80GlVxpcs3q93gqjcUGk63746 intact-crc:EA125172FCC84EFE|rigid:Nx7VxHGscLRewIuh9jZhIYosteE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHV9 uniprotkb:O60925 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 intact:EBI-356919|uniprotkb:Q53F95|uniprotkb:Q96EX6|uniprotkb:B2RD02|ensembl:ENSP00000261813 psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:pfd1_human(display_long)|uniprotkb:PFDN1(gene name)|psi-mi:PFDN1(display_short)|uniprotkb:PFD1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsao et al. (2006) imex:IM-23812|pubmed:16876117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10685338|imex:IM-23812-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N refseq:NP_002613.2|ensembl:ENSG00000113068(gene)|ensembl:ENST00000261813(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O60925|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - - figure legend:3B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/04/13 2015/02/25 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 rogid:repqo0hQgD7XgRAZll8ucK2jwz49606 intact-crc:1FD5150029655944|rigid:ySllMot4hJX8Gp1haHEdN3JTSEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UHV9 uniprotkb:P0C045 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 intact:EBI-9351969 psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:f_hcv77(display_long)|uniprotkb:Alternate reading frame protein/F-protein(gene name synonym)|uniprotkb:Frameshifted protein(gene name synonym)|uniprotkb:p16(gene name synonym)|uniprotkb:p17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsao et al. (2006) imex:IM-23812|pubmed:16876117 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-10685298|imex:IM-23812-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N interpro:IPR002522(Hepatitis C virus capsid protein)|go:"GO:0001848"(complement binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035375"(zymogen binding)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0051494"(negative regulation of cytoskeleton organization)|go:"GO:0097655"(serpin family protein binding) - - - figure legend:1B|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2014/04/13 2015/02/25 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 rogid:UBoCmCg80GlVxpcs3q93gqjcUGk63746 intact-crc:B1A10268672CA4FF|rigid:J+rYG2iuOF3YLwrdM52L3gtribY false v5 tag:c-c enhanced green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P0C045 uniprotkb:Q9UHV9 intact:EBI-9351969 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:f_hcv77(display_long)|uniprotkb:Alternate reading frame protein/F-protein(gene name synonym)|uniprotkb:Frameshifted protein(gene name synonym)|uniprotkb:p16(gene name synonym)|uniprotkb:p17(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsao et al. (2006) imex:IM-23812|pubmed:16876117 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-9392220|imex:IM-23812-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002522(Hepatitis C virus capsid protein)|go:"GO:0001848"(complement binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035375"(zymogen binding)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0051494"(negative regulation of cytoskeleton organization)|go:"GO:0097655"(serpin family protein binding) refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N - - - figure legend:No figure|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/04/13 2015/02/25 rogid:UBoCmCg80GlVxpcs3q93gqjcUGk63746 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 intact-crc:DCCD6E0AEA0B77D9|rigid:J+rYG2iuOF3YLwrdM52L3gtribY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)