#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P03372	uniprotkb:P35222	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kouzmenko et al. (2004)	imex:IM-22202|pubmed:15304487	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9087597|imex:IM-22202-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1	-	-	-	figure legend:Fig. 1A, B|agonist:estrogen|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hct116)|taxid:9606(Human colon carcinoma HCT116 cells)	-	2014/01/17	2014/10/16	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	intact-crc:74BFB439B91668BF|rigid:gHtqRvXpU5h0vE+CUO8ljp0mxTg	false	sufficient binding region:1-396|flag tag:?-?	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
ensembl:ENSG00000160182	uniprotkb:P03372	intact:EBI-5590876	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	psi-mi:tff1_human_gene(display_short)|psi-mi:ENSG00000160182(display_long)	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Kouzmenko et al. (2004)	imex:IM-22202|pubmed:15304487	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9120267|imex:IM-22202-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	-	-	-	figure legend:Fig. 2C|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2014/01/17	2014/10/16	-	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	intact-crc:8D9779EEECF168C1	false	binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000160182	uniprotkb:P35222	intact:EBI-5590876	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563	psi-mi:tff1_human_gene(display_short)|psi-mi:ENSG00000160182(display_long)	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Kouzmenko et al. (2004)	imex:IM-22202|pubmed:15304487	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9087617|imex:IM-22202-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1	-	-	-	figure legend:Fig. 2C|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2014/01/17	2014/10/16	-	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	intact-crc:09D8618F27D51773	false	binding-associated region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000168646	uniprotkb:P03372	intact:EBI-5237192	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	psi-mi:axin2_human_gene(display_short)|psi-mi:ENSG00000168646(display_long)	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Kouzmenko et al. (2004)	imex:IM-22202|pubmed:15304487	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9120279|imex:IM-22202-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	-	-	-	figure legend:Fig. 2D|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2014/01/17	2014/10/16	-	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	intact-crc:190C7A70B2970FB5	false	binding-associated region:?-?	flag tag:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P35222	ensembl:ENSG00000168646	intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563	intact:EBI-5237192	psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym)	psi-mi:axin2_human_gene(display_short)|psi-mi:ENSG00000168646(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Kouzmenko et al. (2004)	imex:IM-22202|pubmed:15304487	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9087653|imex:IM-22202-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1	-	-	-	-	figure legend:Fig. 2D|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw480)|taxid:9606(Human SW480 adenocarcinoma cell line)	-	2014/01/17	2014/10/16	rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606	-	intact-crc:C267B48C483A53A6	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)