#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6Q788	uniprotkb:P11151	intact:EBI-3936819|uniprotkb:B0YIV9|uniprotkb:Q6UWK9|uniprotkb:Q9UBJ3|uniprotkb:Q3MIK6|ensembl:ENSP00000227665|ensembl:ENSP00000399701|ensembl:ENSP00000445002	intact:EBI-8794090|ensembl:ENSBTAP00000017086|uniprotkb:Q17R03	psi-mi:apoa5_human(display_long)|uniprotkb:APOA5(gene name)|psi-mi:APOA5(display_short)|uniprotkb:RAP3(gene name synonym)|uniprotkb:Apolipoprotein A5(gene name synonym)|uniprotkb:Regeneration-associated protein 3(gene name synonym)|uniprotkb:UNQ411/PRO773(orf name)	psi-mi:lipl_bovin(display_long)|uniprotkb:LPL(gene name)|psi-mi:LPL(display_short)|uniprotkb:Phospholipase A1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Fruchart-Najib et al. (2004)	imex:IM-23099|pubmed:15178420	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9256330|imex:IM-23099-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008047"(enzyme activator activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010902"(positive regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0035473"(lipase binding)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050996"(positive regulation of lipid catabolic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055090"(acylglycerol homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060229"(lipase activator activity)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|interpro:IPR000074(Apolipoprotein A1/A4/E)|reactome:R-HSA-1989781|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-8963889|reactome:R-HSA-8963901|go:"GO:0006869"(lipid transport)|ensembl:ENSG00000110243(gene)|ensembl:ENST00000227665(transcript)|ensembl:ENST00000433069(transcript)|ensembl:ENST00000542499(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006641"(triglyceride metabolic process)|refseq:NP_001160070.1|refseq:NP_443200.2|refseq:XP_016872658.1	go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008201"(heparin binding)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009749"(response to glucose)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0042627"(chylomicron)|ensembl:ENSBTAG00000012855(gene)|ensembl:ENSBTAT00000017086(transcript)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|refseq:NP_001068588.1|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002330(Lipoprotein lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|rcsb pdb:6U7M|reactome:R-BTA-8963889|interpro:IPR000734(Lipase)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071813"(lipoprotein particle binding)|dip:DIP-61310N	-	-	-	figure legend:Fig. 4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/10	2014/10/16	rogid:csQ+VFmaGt/8iBV1c3fDYCjqCcI9606	rogid:JxcczPmiAYmUUlp3jiDZub+qEAo9913	intact-crc:C4673B063891E733|rigid:T7StipewfIXUEcMzK3Y2wljg7LE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6Q788	uniprotkb:P06858	intact:EBI-3936819|uniprotkb:B0YIV9|uniprotkb:Q6UWK9|uniprotkb:Q9UBJ3|uniprotkb:Q3MIK6|ensembl:ENSP00000227665|ensembl:ENSP00000399701|ensembl:ENSP00000445002	intact:EBI-715909|uniprotkb:Q16282|uniprotkb:Q16283|uniprotkb:Q96FC4|uniprotkb:B2R5T9|ensembl:ENSP00000497642	psi-mi:apoa5_human(display_long)|uniprotkb:APOA5(gene name)|psi-mi:APOA5(display_short)|uniprotkb:RAP3(gene name synonym)|uniprotkb:Apolipoprotein A5(gene name synonym)|uniprotkb:Regeneration-associated protein 3(gene name synonym)|uniprotkb:UNQ411/PRO773(orf name)	psi-mi:lipl_human(display_long)|uniprotkb:LPL(gene name)|psi-mi:LPL(display_short)|uniprotkb:LIPD(gene name synonym)|uniprotkb:Phospholipase A1(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Fruchart-Najib et al. (2004)	imex:IM-23099|pubmed:15178420	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1332"(bhf-ucl)	intact:EBI-9980672|imex:IM-23099-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008047"(enzyme activator activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010902"(positive regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0035473"(lipase binding)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050996"(positive regulation of lipid catabolic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055090"(acylglycerol homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060229"(lipase activator activity)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|interpro:IPR000074(Apolipoprotein A1/A4/E)|reactome:R-HSA-1989781|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-8963889|reactome:R-HSA-8963901|go:"GO:0006869"(lipid transport)|ensembl:ENSG00000110243(gene)|ensembl:ENST00000227665(transcript)|ensembl:ENST00000433069(transcript)|ensembl:ENST00000542499(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006641"(triglyceride metabolic process)|refseq:NP_001160070.1|refseq:NP_443200.2|refseq:XP_016872658.1	refseq:NP_000228.1|ensembl:ENSG00000175445(gene)|ensembl:ENST00000650287(transcript)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008201"(heparin binding)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009409"(response to cold)|go:"GO:0009749"(response to glucose)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0017129"(triglyceride binding)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002330(Lipoprotein lipase)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|mint:P06858|rcsb pdb:6E7K|rcsb pdb:6OAU|rcsb pdb:6OAZ|rcsb pdb:6OB0|rcsb pdb:6WN4|reactome:R-HSA-381340|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634	-	-	-	figure legend:Fig.4|dataset:Cardiac - Interactions involving cardiac related proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/03/10	2014/11/19	rogid:csQ+VFmaGt/8iBV1c3fDYCjqCcI9606	rogid:PM82k8/f6nyAUhaTSvIUvjVkbYU9606	intact-crc:86845B7BEAF5BFA0|rigid:7ewT1PdhOU8QPAuGWyikQAE6q10	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)