#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0DJZ2-1 uniprotkb:Q80U96 intact:EBI-9673567 intact:EBI-9517348|ensembl:ENSRNOP00000014062 psi-mi:p0djz2-1(display_long)|uniprotkb:NS2(gene name)|psi-mi:NS2(display_short) psi-mi:xpo1_rat(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bodendorf et al. (1999) imex:IM-24162|pubmed:10438867 taxid:648235(mumip)|taxid:648235("Murine minute virus (strain MVM prototype)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9673573|imex:IM-24162-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9673535(isoform-parent) rgd:620517|refseq:NP_445942.1|refseq:XP_006251640.1|ensembl:ENSRNOG00000009935(gene)|ensembl:ENSRNOT00000014062(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3769402|reactome:R-RNO-450520|reactome:R-RNO-5663220|reactome:R-RNO-5687128|reactome:R-RNO-68877|reactome:R-RNO-69273|reactome:R-RNO-9634638|reactome:R-RNO-9648025|reactome:R-RNO-9707616 - isoform-comment:"Splicing isoform (approximately 15% of the molecules)." - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/05/02 2014/10/16 rogid:tyodmIVV/2Q4s5Wq5IrpaHtLL38648235 rogid:o0gfzDl8WvwrZ2yddF7IhyzNbtc10116 intact-crc:750906F46F91143E|rigid:ntbmU9Pwr28nQVKdASC8KPlQiDk false - sufficient binding region:447-1071 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0DJZ2-3 uniprotkb:Q80U96 intact:EBI-9673584 intact:EBI-9517348|ensembl:ENSRNOP00000014062 psi-mi:p0djz2-3(display_long)|uniprotkb:NS2(gene name)|psi-mi:NS2(display_short) psi-mi:xpo1_rat(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bodendorf et al. (1999) imex:IM-24162|pubmed:10438867 taxid:648235(mumip)|taxid:648235("Murine minute virus (strain MVM prototype)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9673579|imex:IM-24162-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9673535(isoform-parent) rgd:620517|refseq:NP_445942.1|refseq:XP_006251640.1|ensembl:ENSRNOG00000009935(gene)|ensembl:ENSRNOT00000014062(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3769402|reactome:R-RNO-450520|reactome:R-RNO-5663220|reactome:R-RNO-5687128|reactome:R-RNO-68877|reactome:R-RNO-69273|reactome:R-RNO-9634638|reactome:R-RNO-9648025|reactome:R-RNO-9707616 - isoform-comment:Minor splicing isoform. - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/05/02 2014/10/16 rogid:rVWdmfCJNMFj6gGJIAPbJ8Dgz2Y648235 rogid:o0gfzDl8WvwrZ2yddF7IhyzNbtc10116 intact-crc:5469067E6E7B145A|rigid:+c7AuGYxHATFtmZ9C38jZb8Ynoo false - sufficient binding region:447-1071 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0DJZ2-2 uniprotkb:Q80U96 intact:EBI-9673559 intact:EBI-9517348|ensembl:ENSRNOP00000014062 psi-mi:p0djz2-2(display_long)|uniprotkb:NS2(gene name)|psi-mi:NS2(display_short) psi-mi:xpo1_rat(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bodendorf et al. (1999) imex:IM-24162|pubmed:10438867 taxid:648235(mumip)|taxid:648235("Murine minute virus (strain MVM prototype)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9673549|imex:IM-24162-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9673535(isoform-parent) rgd:620517|refseq:NP_445942.1|refseq:XP_006251640.1|ensembl:ENSRNOG00000009935(gene)|ensembl:ENSRNOT00000014062(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3769402|reactome:R-RNO-450520|reactome:R-RNO-5663220|reactome:R-RNO-5687128|reactome:R-RNO-68877|reactome:R-RNO-69273|reactome:R-RNO-9634638|reactome:R-RNO-9648025|reactome:R-RNO-9707616 - isoform-comment:"Major splicing isoform (approximately 85% of the molecules)." - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/05/02 2014/10/16 rogid:wLhU7iaup//rW6YAauERVWQ0fhk648235 rogid:o0gfzDl8WvwrZ2yddF7IhyzNbtc10116 intact-crc:44D9063B6E8E1468|rigid:p5abLJl5IxyoxhN0o/orSs8srpY false - sufficient binding region:447-1071 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0DJZ2-2 uniprotkb:Q80U96 intact:EBI-9673559 intact:EBI-9517348|ensembl:ENSRNOP00000014062 psi-mi:p0djz2-2(display_long)|uniprotkb:NS2(gene name)|psi-mi:NS2(display_short) psi-mi:xpo1_rat(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bodendorf et al. (1999) imex:IM-24162|pubmed:10438867 taxid:648235(mumip)|taxid:648235("Murine minute virus (strain MVM prototype)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9517346|imex:IM-24162-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9673535(isoform-parent) rgd:620517|refseq:NP_445942.1|refseq:XP_006251640.1|ensembl:ENSRNOG00000009935(gene)|ensembl:ENSRNOT00000014062(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3769402|reactome:R-RNO-450520|reactome:R-RNO-5663220|reactome:R-RNO-5687128|reactome:R-RNO-68877|reactome:R-RNO-69273|reactome:R-RNO-9634638|reactome:R-RNO-9648025|reactome:R-RNO-9707616 - isoform-comment:"Major splicing isoform (approximately 85% of the molecules)." - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2014/05/02 2014/10/16 rogid:wLhU7iaup//rW6YAauERVWQ0fhk648235 rogid:o0gfzDl8WvwrZ2yddF7IhyzNbtc10116 intact-crc:1C79CBAFC1F90B6B|rigid:p5abLJl5IxyoxhN0o/orSs8srpY false - sufficient binding region:447-1071 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0DJZ2 uniprotkb:Q80U96 intact:EBI-9673535 intact:EBI-9517348|ensembl:ENSRNOP00000014062 psi-mi:ns2_mumip(display_long)|uniprotkb:NS2(gene name)|psi-mi:NS2(display_short) psi-mi:xpo1_rat(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Bodendorf et al. (1999) imex:IM-24162|pubmed:10438867 taxid:648235(mumip)|taxid:648235("Murine minute virus (strain MVM prototype)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9673600|imex:IM-24162-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|go:"GO:0039675"(exit of virus from host cell nucleus through nuclear pore)|go:"GO:0042025"(host cell nucleus) rgd:620517|refseq:NP_445942.1|refseq:XP_006251640.1|ensembl:ENSRNOG00000009935(gene)|ensembl:ENSRNOT00000014062(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3769402|reactome:R-RNO-450520|reactome:R-RNO-5663220|reactome:R-RNO-5687128|reactome:R-RNO-68877|reactome:R-RNO-69273|reactome:R-RNO-9634638|reactome:R-RNO-9648025|reactome:R-RNO-9707616 - - - figure legend:4A and B|comment:14-3-3 proteins have also been precipitated but cannot be mapped to specific proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-frej4)|taxid:10116(Rattus norvegicus FREJ4 cell line, ras-transformed FR3T3 derivative) - 2014/05/02 2014/10/16 rogid:tyodmIVV/2Q4s5Wq5IrpaHtLL38648235 rogid:o0gfzDl8WvwrZ2yddF7IhyzNbtc10116 intact-crc:4EE453D26B4C5E5F|rigid:ntbmU9Pwr28nQVKdASC8KPlQiDk false - 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P0DJZ2 uniprotkb:Q80U96 intact:EBI-9673535 intact:EBI-9517348|ensembl:ENSRNOP00000014062 psi-mi:ns2_mumip(display_long)|uniprotkb:NS2(gene name)|psi-mi:NS2(display_short) psi-mi:xpo1_rat(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Bodendorf et al. (1999) imex:IM-24162|pubmed:10438867 taxid:648235(mumip)|taxid:648235("Murine minute virus (strain MVM prototype)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9673608|imex:IM-24162-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|go:"GO:0039675"(exit of virus from host cell nucleus through nuclear pore)|go:"GO:0042025"(host cell nucleus) rgd:620517|refseq:NP_445942.1|refseq:XP_006251640.1|ensembl:ENSRNOG00000009935(gene)|ensembl:ENSRNOT00000014062(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3769402|reactome:R-RNO-450520|reactome:R-RNO-5663220|reactome:R-RNO-5687128|reactome:R-RNO-68877|reactome:R-RNO-69273|reactome:R-RNO-9634638|reactome:R-RNO-9648025|reactome:R-RNO-9707616 - - - figure legend:4B|comment:14-3-3 proteins have also been precipitated but cannot be mapped to specific proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-frej4)|taxid:10116(Rattus norvegicus FREJ4 cell line, ras-transformed FR3T3 derivative) - 2014/05/02 2015/05/15 rogid:tyodmIVV/2Q4s5Wq5IrpaHtLL38648235 rogid:o0gfzDl8WvwrZ2yddF7IhyzNbtc10116 intact-crc:37387257BC419BC4|rigid:ntbmU9Pwr28nQVKdASC8KPlQiDk false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q6P5F9 uniprotkb:P0DJZ2 intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178 intact:EBI-9673535 psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:ns2_mumip(display_long)|uniprotkb:NS2(gene name)|psi-mi:NS2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Bodendorf et al. (1999) imex:IM-24162|pubmed:10438867 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:648235(mumip)|taxid:648235("Murine minute virus (strain MVM prototype)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9673662|imex:IM-24162-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|go:"GO:0039675"(exit of virus from host cell nucleus through nuclear pore)|go:"GO:0042025"(host cell nucleus) - - - figure legend:5A and B|comment:"Infection with NS2 thr149ala mutant (impaired phosohorylation) also interacted."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-a9)|taxid:10090(Mus musculus A9 fibroblasts) - 2014/05/02 2014/10/16 rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090 rogid:tyodmIVV/2Q4s5Wq5IrpaHtLL38648235 intact-crc:63A423EB137B86DC|rigid:nNRpaww9X7459J/jywg9vQu4Vj0 false 35s radiolabel:?-? - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q6P5F9 uniprotkb:P0DJZ2 intact:EBI-2550236|ensembl:ENSMUSP00000020538|ensembl:ENSMUSP00000099933|ensembl:ENSMUSP00000099934|ensembl:ENSMUSP00000105178 intact:EBI-9673535 psi-mi:xpo1_mouse(display_long)|uniprotkb:Xpo1(gene name)|psi-mi:Xpo1(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:ns2_mumip(display_long)|uniprotkb:NS2(gene name)|psi-mi:NS2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Bodendorf et al. (1999) imex:IM-24162|pubmed:10438867 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:648235(mumip)|taxid:648235("Murine minute virus (strain MVM prototype)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-9673679|imex:IM-24162-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3NC0|rcsb pdb:3NC1|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3769402|reactome:R-MMU-450520|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-68877|reactome:R-MMU-69273|reactome:R-MMU-9634638|reactome:R-MMU-9648025|reactome:R-MMU-9707616|rcsb pdb:3NBZ|ensembl:ENSMUSG00000020290(gene)|ensembl:ENSMUST00000020538(transcript)|ensembl:ENSMUST00000102869(transcript)|ensembl:ENSMUST00000102870(transcript)|ensembl:ENSMUST00000109551(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0042176"(regulation of protein catabolic process)|rcsb pdb:3GJX|rcsb pdb:3NBY|refseq:NP_001030303.1|refseq:NP_598775.2|refseq:XP_006514493.1|dip:DIP-48612N rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|go:"GO:0039675"(exit of virus from host cell nucleus through nuclear pore)|go:"GO:0042025"(host cell nucleus) - - comment:NS2 non-phosphorylated form detected figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-a9)|taxid:10090(Mus musculus A9 fibroblasts) - 2014/05/02 2014/10/16 rogid:k02EX8YlQCgjt5EyEXvTFHQNPCI10090 rogid:tyodmIVV/2Q4s5Wq5IrpaHtLL38648235 intact-crc:CE66336BC43F4561|rigid:nNRpaww9X7459J/jywg9vQu4Vj0 false - 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)