#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62942 uniprotkb:Q90984 intact:EBI-1027571|uniprotkb:P20071|uniprotkb:Q4VC47|uniprotkb:Q6FGD9|uniprotkb:Q6LEU3|uniprotkb:Q9H103|uniprotkb:Q9H566|uniprotkb:D3DVW6|ensembl:ENSP00000371138|ensembl:ENSP00000371143|ensembl:ENSP00000383003|ensembl:ENSP00000503033|ensembl:ENSP00000503152 intact:EBI-6661884 psi-mi:fkb1a_human(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym) psi-mi:q90984_chick(display_long)|uniprotkb:RyR1(gene name)|psi-mi:RyR1(display_short) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6656585|imex:IM-26050-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088832(gene)|ensembl:ENST00000381719(transcript)|ensembl:ENST00000381724(transcript)|ensembl:ENST00000400137(transcript)|ensembl:ENST00000677335(transcript)|ensembl:ENST00000678408(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005527"(macrolide binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1A7X|rcsb pdb:1B6C|rcsb pdb:1BKF|rcsb pdb:1BL4|rcsb pdb:1D6O|rcsb pdb:1D7H|rcsb pdb:1D7I|rcsb pdb:1D7J|rcsb pdb:1EYM|rcsb pdb:1F40|rcsb pdb:1FAP|rcsb pdb:1FKB|rcsb pdb:1FKD|rcsb pdb:1FKF|rcsb pdb:1FKG|rcsb pdb:1FKH|rcsb pdb:1FKI|rcsb pdb:2DG4|rcsb pdb:2DG9|rcsb pdb:2FAP|rcsb pdb:2FKE|rcsb pdb:2ND5|rcsb pdb:2PPN|rcsb pdb:2PPO|rcsb pdb:2PPP|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:1FKJ|rcsb pdb:3H9R|rcsb pdb:3MDY|rcsb pdb:4DH0|rcsb pdb:4FAP|rcsb pdb:1FKR|rcsb pdb:4IPX|rcsb pdb:4N19|rcsb pdb:4ODP|rcsb pdb:4ODQ|rcsb pdb:4ODR|rcsb pdb:5I7P|rcsb pdb:5I7Q|rcsb pdb:6I1S|rcsb pdb:1FKS|rcsb pdb:6M4U|rcsb pdb:6OQA|rcsb pdb:6VCU|rcsb pdb:6YF0|rcsb pdb:6YF1|rcsb pdb:6YF2|rcsb pdb:6YF3|reactome:R-HSA-166208|rcsb pdb:1FKT|reactome:R-HSA-2025928|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3656535|rcsb pdb:1J4H|rcsb pdb:1J4I|reactome:R-HSA-9679191|rcsb pdb:1J4R|rcsb pdb:1NSG|rcsb pdb:1QPF|rcsb pdb:1QPL|rcsb pdb:2DG3|refseq:NP_000792.1|refseq:NP_463460.1|dip:DIP-29710N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity) interpro:IPR033215|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6) - - - figure legend:Table 2, 3 and 4. Figure 4|comment:Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle RYR1 contains 4 binding sites for FKBP12|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2017/09/02 rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9606 rogid:Ov9RnZkDk8++0ko2WdLrW7BJyts9031 intact-crc:69032BD159EE4E8A|rigid:SkVAivii4FA2X3mpf1dHDoR2aBE false radiolabel:?-? - 4 4 psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P62942 intact:EBI-6676479 intact:EBI-1027571|uniprotkb:P20071|uniprotkb:Q4VC47|uniprotkb:Q6FGD9|uniprotkb:Q6LEU3|uniprotkb:Q9H103|uniprotkb:Q9H566|uniprotkb:D3DVW6|ensembl:ENSP00000371138|ensembl:ENSP00000371143|ensembl:ENSP00000383003|ensembl:ENSP00000503033|ensembl:ENSP00000503152 - psi-mi:fkb1a_human(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym) psi-mi:f7e4c0_xentr(display_short)|psi-mi:EBI-6676479(display_long)|uniprotkb:dtwd1(gene name synonym)|uniprotkb:ryr1(gene name)|psi-mi:ryr1(display_short) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6676451|imex:IM-26050-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088832(gene)|ensembl:ENST00000381719(transcript)|ensembl:ENST00000381724(transcript)|ensembl:ENST00000400137(transcript)|ensembl:ENST00000677335(transcript)|ensembl:ENST00000678408(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005527"(macrolide binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1A7X|rcsb pdb:1B6C|rcsb pdb:1BKF|rcsb pdb:1BL4|rcsb pdb:1D6O|rcsb pdb:1D7H|rcsb pdb:1D7I|rcsb pdb:1D7J|rcsb pdb:1EYM|rcsb pdb:1F40|rcsb pdb:1FAP|rcsb pdb:1FKB|rcsb pdb:1FKD|rcsb pdb:1FKF|rcsb pdb:1FKG|rcsb pdb:1FKH|rcsb pdb:1FKI|rcsb pdb:2DG4|rcsb pdb:2DG9|rcsb pdb:2FAP|rcsb pdb:2FKE|rcsb pdb:2ND5|rcsb pdb:2PPN|rcsb pdb:2PPO|rcsb pdb:2PPP|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:1FKJ|rcsb pdb:3H9R|rcsb pdb:3MDY|rcsb pdb:4DH0|rcsb pdb:4FAP|rcsb pdb:1FKR|rcsb pdb:4IPX|rcsb pdb:4N19|rcsb pdb:4ODP|rcsb pdb:4ODQ|rcsb pdb:4ODR|rcsb pdb:5I7P|rcsb pdb:5I7Q|rcsb pdb:6I1S|rcsb pdb:1FKS|rcsb pdb:6M4U|rcsb pdb:6OQA|rcsb pdb:6VCU|rcsb pdb:6YF0|rcsb pdb:6YF1|rcsb pdb:6YF2|rcsb pdb:6YF3|reactome:R-HSA-166208|rcsb pdb:1FKT|reactome:R-HSA-2025928|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3656535|rcsb pdb:1J4H|rcsb pdb:1J4I|reactome:R-HSA-9679191|rcsb pdb:1J4R|rcsb pdb:1NSG|rcsb pdb:1QPF|rcsb pdb:1QPL|rcsb pdb:2DG3|refseq:NP_000792.1|refseq:NP_463460.1|dip:DIP-29710N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity) reactome:R-XTR-5578775|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005509"(calcium ion binding)|reactome:R-XTR-2672351|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0048763"(calcium-induced calcium release activity)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033215|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR011992(EF-Hand type)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|ensembl:ENSXETP00000006174|go:"GO:0005623"(obsolete cell)|ensembl:ENSXETG00000008787|ensembl:ENSXETT00000031675 - - no-uniprot-update:no candidate replacement found figure legend:Table 2, 3 and 4. Figure 4|comment:Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle RYR1 contains 4 binding sites for FKBP12|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2020/01/08 rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9606 rogid:RWclkHfI+8l1Is2tDFeV3Ln3RuQ8364 intact-crc:01BA3524F8210DE8|rigid:S7gheYSWlHucJUSsDVohv/1qHrU false radiolabel:?-? - 4 4 psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P11716 uniprotkb:P62942 intact:EBI-6477441 intact:EBI-1027571|uniprotkb:P20071|uniprotkb:Q4VC47|uniprotkb:Q6FGD9|uniprotkb:Q6LEU3|uniprotkb:Q9H103|uniprotkb:Q9H566|uniprotkb:D3DVW6|ensembl:ENSP00000371138|ensembl:ENSP00000371143|ensembl:ENSP00000383003|ensembl:ENSP00000503033|ensembl:ENSP00000503152 psi-mi:ryr1_rabit(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym) psi-mi:fkb1a_human(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6662027|imex:IM-26050-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:2BCX|rcsb pdb:2XOA|rcsb pdb:3HSM|rcsb pdb:3ILA|rcsb pdb:3J8H|rcsb pdb:3RQR|rcsb pdb:4ERT|rcsb pdb:4ESU|rcsb pdb:4ETT|go:"GO:0035381"(ATP-gated ion channel activity)|rcsb pdb:4ETU|rcsb pdb:4I0Y|rcsb pdb:4I1E|go:"GO:0042802"(identical protein binding)|rcsb pdb:4I2S|rcsb pdb:4I37|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|rcsb pdb:4I3N|rcsb pdb:4I6I|rcsb pdb:4I7I|rcsb pdb:4I8M|rcsb pdb:4I96|rcsb pdb:4P9J|rcsb pdb:4UWA|go:"GO:0044325"(transmembrane transporter binding)|rcsb pdb:4UWE|rcsb pdb:5C30|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|rcsb pdb:5J8V|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6FG3|rcsb pdb:6FOO|rcsb pdb:6M2W|rcsb pdb:6WOT|rcsb pdb:7CF9|refseq:NP_001095188.1|dip:DIP-41872N ensembl:ENSG00000088832(gene)|ensembl:ENST00000381719(transcript)|ensembl:ENST00000381724(transcript)|ensembl:ENST00000400137(transcript)|ensembl:ENST00000677335(transcript)|ensembl:ENST00000678408(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005527"(macrolide binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1A7X|rcsb pdb:1B6C|rcsb pdb:1BKF|rcsb pdb:1BL4|rcsb pdb:1D6O|rcsb pdb:1D7H|rcsb pdb:1D7I|rcsb pdb:1D7J|rcsb pdb:1EYM|rcsb pdb:1F40|rcsb pdb:1FAP|rcsb pdb:1FKB|rcsb pdb:1FKD|rcsb pdb:1FKF|rcsb pdb:1FKG|rcsb pdb:1FKH|rcsb pdb:1FKI|rcsb pdb:2DG4|rcsb pdb:2DG9|rcsb pdb:2FAP|rcsb pdb:2FKE|rcsb pdb:2ND5|rcsb pdb:2PPN|rcsb pdb:2PPO|rcsb pdb:2PPP|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:1FKJ|rcsb pdb:3H9R|rcsb pdb:3MDY|rcsb pdb:4DH0|rcsb pdb:4FAP|rcsb pdb:1FKR|rcsb pdb:4IPX|rcsb pdb:4N19|rcsb pdb:4ODP|rcsb pdb:4ODQ|rcsb pdb:4ODR|rcsb pdb:5I7P|rcsb pdb:5I7Q|rcsb pdb:6I1S|rcsb pdb:1FKS|rcsb pdb:6M4U|rcsb pdb:6OQA|rcsb pdb:6VCU|rcsb pdb:6YF0|rcsb pdb:6YF1|rcsb pdb:6YF2|rcsb pdb:6YF3|reactome:R-HSA-166208|rcsb pdb:1FKT|reactome:R-HSA-2025928|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3656535|rcsb pdb:1J4H|rcsb pdb:1J4I|reactome:R-HSA-9679191|rcsb pdb:1J4R|rcsb pdb:1NSG|rcsb pdb:1QPF|rcsb pdb:1QPL|rcsb pdb:2DG3|refseq:NP_000792.1|refseq:NP_463460.1|dip:DIP-29710N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity) - - - figure legend:Table 2, 3 and 4. Figure 4|comment:Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle RYR1 contains 4 binding sites for FKBP12|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2017/09/02 rogid:QUlch7kTlopwGM10g+OXd4rODXo9986 rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9606 intact-crc:04B4985B9955EC13|rigid:MKTmqferWrt3wA0OLQL9UJMrvH0 false - radiolabel:?-? 4 4 psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P62942 intact:EBI-6692507 intact:EBI-1027571|uniprotkb:P20071|uniprotkb:Q4VC47|uniprotkb:Q6FGD9|uniprotkb:Q6LEU3|uniprotkb:Q9H103|uniprotkb:Q9H566|uniprotkb:D3DVW6|ensembl:ENSP00000371138|ensembl:ENSP00000371143|ensembl:ENSP00000383003|ensembl:ENSP00000503033|ensembl:ENSP00000503152 - psi-mi:fkb1a_human(display_long)|uniprotkb:FKBP1A(gene name)|psi-mi:FKBP1A(display_short)|uniprotkb:FKBP1(gene name synonym)|uniprotkb:FKBP12(gene name synonym)|uniprotkb:FK506-binding protein 1A(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP12(gene name synonym)|uniprotkb:12 kDa FK506-binding protein(gene name synonym)|uniprotkb:Calstabin-1(gene name synonym) psi-mi:ryr1_oncmy_protein(display_short)|psi-mi:EBI-6692507(display_long) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:8022(oncmy)|taxid:8022("Oncorhynchus mykiss (Rainbow trout)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6838589|imex:IM-26050-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000088832(gene)|ensembl:ENST00000381719(transcript)|ensembl:ENST00000381724(transcript)|ensembl:ENST00000400137(transcript)|ensembl:ENST00000677335(transcript)|ensembl:ENST00000678408(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005527"(macrolide binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0014802"(terminal cisterna)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031312"(extrinsic component of organelle membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0042026"(protein refolding)|go:"GO:0042110"(T cell activation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0048185"(activin binding)|go:"GO:0050776"(regulation of immune response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0098562"(cytoplasmic side of membrane)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1A7X|rcsb pdb:1B6C|rcsb pdb:1BKF|rcsb pdb:1BL4|rcsb pdb:1D6O|rcsb pdb:1D7H|rcsb pdb:1D7I|rcsb pdb:1D7J|rcsb pdb:1EYM|rcsb pdb:1F40|rcsb pdb:1FAP|rcsb pdb:1FKB|rcsb pdb:1FKD|rcsb pdb:1FKF|rcsb pdb:1FKG|rcsb pdb:1FKH|rcsb pdb:1FKI|rcsb pdb:2DG4|rcsb pdb:2DG9|rcsb pdb:2FAP|rcsb pdb:2FKE|rcsb pdb:2ND5|rcsb pdb:2PPN|rcsb pdb:2PPO|rcsb pdb:2PPP|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:1FKJ|rcsb pdb:3H9R|rcsb pdb:3MDY|rcsb pdb:4DH0|rcsb pdb:4FAP|rcsb pdb:1FKR|rcsb pdb:4IPX|rcsb pdb:4N19|rcsb pdb:4ODP|rcsb pdb:4ODQ|rcsb pdb:4ODR|rcsb pdb:5I7P|rcsb pdb:5I7Q|rcsb pdb:6I1S|rcsb pdb:1FKS|rcsb pdb:6M4U|rcsb pdb:6OQA|rcsb pdb:6VCU|rcsb pdb:6YF0|rcsb pdb:6YF1|rcsb pdb:6YF2|rcsb pdb:6YF3|reactome:R-HSA-166208|rcsb pdb:1FKT|reactome:R-HSA-2025928|reactome:R-HSA-2173789|reactome:R-HSA-2173791|reactome:R-HSA-3656535|rcsb pdb:1J4H|rcsb pdb:1J4I|reactome:R-HSA-9679191|rcsb pdb:1J4R|rcsb pdb:1NSG|rcsb pdb:1QPF|rcsb pdb:1QPL|rcsb pdb:2DG3|refseq:NP_000792.1|refseq:NP_463460.1|dip:DIP-29710N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity) - - - comment:Similar to O13054 figure legend:Table 2, 3 and 4. Figure 4|comment:Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle RYR1 contains 4 binding sites for FKBP12|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2017/09/02 rogid:3eikHNIIVs8AFM7PYVWurI/9KUY9606 - intact-crc:C8ACB52110CF3EF5 false radiolabel:?-? - 5 5 psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q90984 uniprotkb:P68106 intact:EBI-6661884 intact:EBI-6693977|uniprotkb:Q13664|uniprotkb:Q16645|uniprotkb:Q53TM2|uniprotkb:Q9BQ40|ensembl:ENSP00000370373 psi-mi:q90984_chick(display_long)|uniprotkb:RyR1(gene name)|psi-mi:RyR1(display_short) psi-mi:fkb1b_human(display_long)|uniprotkb:FKBP1B(gene name)|psi-mi:FKBP1B(display_short)|uniprotkb:FKBP12.6(gene name synonym)|uniprotkb:FKBP1L(gene name synonym)|uniprotkb:FKBP9(gene name synonym)|uniprotkb:OTK4(gene name synonym)|uniprotkb:12.6 kDa FK506-binding protein(gene name synonym)|uniprotkb:FK506-binding protein 1B(gene name synonym)|uniprotkb:Immunophilin FKBP12.6(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:h-FKBP-12(gene name synonym) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6661996|imex:IM-26050-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033215|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6) refseq:NP_004107.1|refseq:NP_473374.1|ensembl:ENSG00000119782(gene)|ensembl:ENST00000380986(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0009749"(response to glucose)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042026"(protein refolding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051775"(response to redox state)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1C9H|rcsb pdb:4C02|rcsb pdb:4IQ2|rcsb pdb:4IQC|rcsb pdb:5HKG|rcsb pdb:5L1D|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6JGZ|rcsb pdb:6JH6|rcsb pdb:6JHN|rcsb pdb:6JI0|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRR|rcsb pdb:6JRS|rcsb pdb:6M2W|rcsb pdb:6W1N|rcsb pdb:6WOT|rcsb pdb:6WOU|rcsb pdb:6WOV|rcsb pdb:6X32|rcsb pdb:6X33|rcsb pdb:6X34|rcsb pdb:6X35|rcsb pdb:6X36|rcsb pdb:7CF9|rcsb pdb:7JMF|rcsb pdb:7JMG|rcsb pdb:6PV6|rcsb pdb:7JMH|rcsb pdb:7JMI|rcsb pdb:7JMJ|reactome:R-HSA-2672351|reactome:R-HSA-5578775|dip:DIP-48796N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity) - - - figure legend:Table 2, 3 and 4. Figure 4|comment:Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle RYR1 contains 4 binding sites for FKBP12.6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2017/09/02 rogid:Ov9RnZkDk8++0ko2WdLrW7BJyts9031 rogid:n8ztvcTI/NJmcWSVyVusxO2BEXY9606 intact-crc:EC2C8BD08AE14EC3|rigid:NYKUmMjhsymqXeDLokp38AA5lE8 false - radiolabel:?-? 4 4 psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P68106 intact:EBI-6692507 intact:EBI-6693977|uniprotkb:Q13664|uniprotkb:Q16645|uniprotkb:Q53TM2|uniprotkb:Q9BQ40|ensembl:ENSP00000370373 - psi-mi:fkb1b_human(display_long)|uniprotkb:FKBP1B(gene name)|psi-mi:FKBP1B(display_short)|uniprotkb:FKBP12.6(gene name synonym)|uniprotkb:FKBP1L(gene name synonym)|uniprotkb:FKBP9(gene name synonym)|uniprotkb:OTK4(gene name synonym)|uniprotkb:12.6 kDa FK506-binding protein(gene name synonym)|uniprotkb:FK506-binding protein 1B(gene name synonym)|uniprotkb:Immunophilin FKBP12.6(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:h-FKBP-12(gene name synonym) psi-mi:ryr1_oncmy_protein(display_short)|psi-mi:EBI-6692507(display_long) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:8022(oncmy)|taxid:8022("Oncorhynchus mykiss (Rainbow trout)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6838609|imex:IM-26050-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004107.1|refseq:NP_473374.1|ensembl:ENSG00000119782(gene)|ensembl:ENST00000380986(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0009749"(response to glucose)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042026"(protein refolding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051775"(response to redox state)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1C9H|rcsb pdb:4C02|rcsb pdb:4IQ2|rcsb pdb:4IQC|rcsb pdb:5HKG|rcsb pdb:5L1D|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6JGZ|rcsb pdb:6JH6|rcsb pdb:6JHN|rcsb pdb:6JI0|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRR|rcsb pdb:6JRS|rcsb pdb:6M2W|rcsb pdb:6W1N|rcsb pdb:6WOT|rcsb pdb:6WOU|rcsb pdb:6WOV|rcsb pdb:6X32|rcsb pdb:6X33|rcsb pdb:6X34|rcsb pdb:6X35|rcsb pdb:6X36|rcsb pdb:7CF9|rcsb pdb:7JMF|rcsb pdb:7JMG|rcsb pdb:6PV6|rcsb pdb:7JMH|rcsb pdb:7JMI|rcsb pdb:7JMJ|reactome:R-HSA-2672351|reactome:R-HSA-5578775|dip:DIP-48796N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity) - - - comment:Similar to O13054 figure legend:Table 2, 3 and 4. Figure 4|comment:Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle RYR1 contains 4 binding sites for FKBP12.6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2017/09/02 rogid:n8ztvcTI/NJmcWSVyVusxO2BEXY9606 - intact-crc:A454542C62FAB2ED false radiolabel:?-? - 4 4 psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) intact:EBI-6676479 uniprotkb:P68106 - intact:EBI-6693977|uniprotkb:Q13664|uniprotkb:Q16645|uniprotkb:Q53TM2|uniprotkb:Q9BQ40|ensembl:ENSP00000370373 psi-mi:f7e4c0_xentr(display_short)|psi-mi:EBI-6676479(display_long)|uniprotkb:dtwd1(gene name synonym)|uniprotkb:ryr1(gene name)|psi-mi:ryr1(display_short) psi-mi:fkb1b_human(display_long)|uniprotkb:FKBP1B(gene name)|psi-mi:FKBP1B(display_short)|uniprotkb:FKBP12.6(gene name synonym)|uniprotkb:FKBP1L(gene name synonym)|uniprotkb:FKBP9(gene name synonym)|uniprotkb:OTK4(gene name synonym)|uniprotkb:12.6 kDa FK506-binding protein(gene name synonym)|uniprotkb:FK506-binding protein 1B(gene name synonym)|uniprotkb:Immunophilin FKBP12.6(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:h-FKBP-12(gene name synonym) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6676448|imex:IM-26050-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-XTR-5578775|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005509"(calcium ion binding)|reactome:R-XTR-2672351|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0048763"(calcium-induced calcium release activity)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033215|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR011992(EF-Hand type)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|ensembl:ENSXETP00000006174|go:"GO:0005623"(obsolete cell)|ensembl:ENSXETG00000008787|ensembl:ENSXETT00000031675 refseq:NP_004107.1|refseq:NP_473374.1|ensembl:ENSG00000119782(gene)|ensembl:ENST00000380986(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0009749"(response to glucose)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042026"(protein refolding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051775"(response to redox state)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1C9H|rcsb pdb:4C02|rcsb pdb:4IQ2|rcsb pdb:4IQC|rcsb pdb:5HKG|rcsb pdb:5L1D|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6JGZ|rcsb pdb:6JH6|rcsb pdb:6JHN|rcsb pdb:6JI0|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRR|rcsb pdb:6JRS|rcsb pdb:6M2W|rcsb pdb:6W1N|rcsb pdb:6WOT|rcsb pdb:6WOU|rcsb pdb:6WOV|rcsb pdb:6X32|rcsb pdb:6X33|rcsb pdb:6X34|rcsb pdb:6X35|rcsb pdb:6X36|rcsb pdb:7CF9|rcsb pdb:7JMF|rcsb pdb:7JMG|rcsb pdb:6PV6|rcsb pdb:7JMH|rcsb pdb:7JMI|rcsb pdb:7JMJ|reactome:R-HSA-2672351|reactome:R-HSA-5578775|dip:DIP-48796N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity) - no-uniprot-update:no candidate replacement found - figure legend:Table 2, 3 and 4. Figure 4|comment:Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle RYR1 contains 4 binding sites for FKBP12.6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2020/01/08 rogid:RWclkHfI+8l1Is2tDFeV3Ln3RuQ8364 rogid:n8ztvcTI/NJmcWSVyVusxO2BEXY9606 intact-crc:4CBAF4E483AEC1BA|rigid:t/qB/X50vc5l2JL5t/Ha4S/qX/w false - radiolabel:?-? 4 4 psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P68106 uniprotkb:P11716 intact:EBI-6693977|uniprotkb:Q13664|uniprotkb:Q16645|uniprotkb:Q53TM2|uniprotkb:Q9BQ40|ensembl:ENSP00000370373 intact:EBI-6477441 psi-mi:fkb1b_human(display_long)|uniprotkb:FKBP1B(gene name)|psi-mi:FKBP1B(display_short)|uniprotkb:FKBP12.6(gene name synonym)|uniprotkb:FKBP1L(gene name synonym)|uniprotkb:FKBP9(gene name synonym)|uniprotkb:OTK4(gene name synonym)|uniprotkb:12.6 kDa FK506-binding protein(gene name synonym)|uniprotkb:FK506-binding protein 1B(gene name synonym)|uniprotkb:Immunophilin FKBP12.6(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:h-FKBP-12(gene name synonym) psi-mi:ryr1_rabit(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6662024|imex:IM-26050-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004107.1|refseq:NP_473374.1|ensembl:ENSG00000119782(gene)|ensembl:ENST00000380986(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0009749"(response to glucose)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033197"(response to vitamin E)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042026"(protein refolding)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051775"(response to redox state)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1C9H|rcsb pdb:4C02|rcsb pdb:4IQ2|rcsb pdb:4IQC|rcsb pdb:5HKG|rcsb pdb:5L1D|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6JGZ|rcsb pdb:6JH6|rcsb pdb:6JHN|rcsb pdb:6JI0|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRR|rcsb pdb:6JRS|rcsb pdb:6M2W|rcsb pdb:6W1N|rcsb pdb:6WOT|rcsb pdb:6WOU|rcsb pdb:6WOV|rcsb pdb:6X32|rcsb pdb:6X33|rcsb pdb:6X34|rcsb pdb:6X35|rcsb pdb:6X36|rcsb pdb:7CF9|rcsb pdb:7JMF|rcsb pdb:7JMG|rcsb pdb:6PV6|rcsb pdb:7JMH|rcsb pdb:7JMI|rcsb pdb:7JMJ|reactome:R-HSA-2672351|reactome:R-HSA-5578775|dip:DIP-48796N|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity) go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:2BCX|rcsb pdb:2XOA|rcsb pdb:3HSM|rcsb pdb:3ILA|rcsb pdb:3J8H|rcsb pdb:3RQR|rcsb pdb:4ERT|rcsb pdb:4ESU|rcsb pdb:4ETT|go:"GO:0035381"(ATP-gated ion channel activity)|rcsb pdb:4ETU|rcsb pdb:4I0Y|rcsb pdb:4I1E|go:"GO:0042802"(identical protein binding)|rcsb pdb:4I2S|rcsb pdb:4I37|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|rcsb pdb:4I3N|rcsb pdb:4I6I|rcsb pdb:4I7I|rcsb pdb:4I8M|rcsb pdb:4I96|rcsb pdb:4P9J|rcsb pdb:4UWA|go:"GO:0044325"(transmembrane transporter binding)|rcsb pdb:4UWE|rcsb pdb:5C30|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|rcsb pdb:5J8V|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6FG3|rcsb pdb:6FOO|rcsb pdb:6M2W|rcsb pdb:6WOT|rcsb pdb:7CF9|refseq:NP_001095188.1|dip:DIP-41872N - - - figure legend:Table 2, 3 and 4. Figure 4|comment:Tissue- Terminal cisternae of sarcoplasmic reticulum of skeletal muscle RYR1 contains 4 binding sites for FKBP12.6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2017/09/02 rogid:n8ztvcTI/NJmcWSVyVusxO2BEXY9606 rogid:QUlch7kTlopwGM10g+OXd4rODXo9986 intact-crc:7C8924E9AC5FBE42|rigid:/SOFMheQr+df7cxPGA5ARKXSJpo false radiolabel:?-? - 3 3 psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:8925" intact:EBI-6676479 intact:EBI-6857858 - psi-mi:ryanodine(display_short)|psi-mi:"CHEBI:8925"(display_long) psi-mi:f7e4c0_xentr(display_short)|psi-mi:EBI-6676479(display_long)|uniprotkb:dtwd1(gene name synonym)|uniprotkb:ryr1(gene name)|psi-mi:ryr1(display_short) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:8364(xentr)|taxid:8364("Xenopus tropicalis (Western clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6857883|imex:IM-26050-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - reactome:R-XTR-5578775|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005509"(calcium ion binding)|reactome:R-XTR-2672351|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0048763"(calcium-induced calcium release activity)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033215|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR011992(EF-Hand type)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|ensembl:ENSXETP00000006174|go:"GO:0005623"(obsolete cell)|ensembl:ENSXETG00000008787|ensembl:ENSXETT00000031675 - - no-uniprot-update:no candidate replacement found figure legend:2 and table 2,3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2020/01/08 - rogid:RWclkHfI+8l1Is2tDFeV3Ln3RuQ8364 intact-crc:2F8AC8410AC2C749 false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:8925" uniprotkb:P11716 intact:EBI-6857858 intact:EBI-6477441 psi-mi:ryanodine(display_short)|psi-mi:"CHEBI:8925"(display_long) psi-mi:ryr1_rabit(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6857875|imex:IM-26050-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:2BCX|rcsb pdb:2XOA|rcsb pdb:3HSM|rcsb pdb:3ILA|rcsb pdb:3J8H|rcsb pdb:3RQR|rcsb pdb:4ERT|rcsb pdb:4ESU|rcsb pdb:4ETT|go:"GO:0035381"(ATP-gated ion channel activity)|rcsb pdb:4ETU|rcsb pdb:4I0Y|rcsb pdb:4I1E|go:"GO:0042802"(identical protein binding)|rcsb pdb:4I2S|rcsb pdb:4I37|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|rcsb pdb:4I3N|rcsb pdb:4I6I|rcsb pdb:4I7I|rcsb pdb:4I8M|rcsb pdb:4I96|rcsb pdb:4P9J|rcsb pdb:4UWA|go:"GO:0044325"(transmembrane transporter binding)|rcsb pdb:4UWE|rcsb pdb:5C30|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|rcsb pdb:5J8V|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6FG3|rcsb pdb:6FOO|rcsb pdb:6M2W|rcsb pdb:6WOT|rcsb pdb:7CF9|refseq:NP_001095188.1|dip:DIP-41872N - - - figure legend:2 and table 2,3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2019/01/30 - rogid:QUlch7kTlopwGM10g+OXd4rODXo9986 intact-crc:403E2341AF07C339 false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:8925" uniprotkb:P11716 intact:EBI-6857858 intact:EBI-6477441 psi-mi:ryanodine(display_short)|psi-mi:"CHEBI:8925"(display_long) psi-mi:ryr1_rabit(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6857875|imex:IM-26050-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:2BCX|rcsb pdb:2XOA|rcsb pdb:3HSM|rcsb pdb:3ILA|rcsb pdb:3J8H|rcsb pdb:3RQR|rcsb pdb:4ERT|rcsb pdb:4ESU|rcsb pdb:4ETT|go:"GO:0035381"(ATP-gated ion channel activity)|rcsb pdb:4ETU|rcsb pdb:4I0Y|rcsb pdb:4I1E|go:"GO:0042802"(identical protein binding)|rcsb pdb:4I2S|rcsb pdb:4I37|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|rcsb pdb:4I3N|rcsb pdb:4I6I|rcsb pdb:4I7I|rcsb pdb:4I8M|rcsb pdb:4I96|rcsb pdb:4P9J|rcsb pdb:4UWA|go:"GO:0044325"(transmembrane transporter binding)|rcsb pdb:4UWE|rcsb pdb:5C30|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|rcsb pdb:5J8V|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6FG3|rcsb pdb:6FOO|rcsb pdb:6M2W|rcsb pdb:6WOT|rcsb pdb:7CF9|refseq:NP_001095188.1|dip:DIP-41872N - - - figure legend:2 and table 2,3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2019/01/30 - rogid:QUlch7kTlopwGM10g+OXd4rODXo9986 intact-crc:403E2341AF07C339 false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:8925" uniprotkb:Q90984 intact:EBI-6857858 intact:EBI-6661884 psi-mi:ryanodine(display_short)|psi-mi:"CHEBI:8925"(display_long) psi-mi:q90984_chick(display_long)|uniprotkb:RyR1(gene name)|psi-mi:RyR1(display_short) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6857854|imex:IM-26050-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - interpro:IPR033215|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6) - - - figure legend:2 and table 2,3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2019/01/30 - rogid:Ov9RnZkDk8++0ko2WdLrW7BJyts9031 intact-crc:79EF3EF44D7B88D0 false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q90984 uniprotkb:P11716 intact:EBI-6661884 intact:EBI-6477441 psi-mi:q90984_chick(display_long)|uniprotkb:RyR1(gene name)|psi-mi:RyR1(display_short) psi-mi:ryr1_rabit(display_long)|uniprotkb:RYR1(gene name)|psi-mi:RYR1(display_short)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6857854|imex:IM-26050-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR033215|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6) go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|rcsb pdb:2BCX|rcsb pdb:2XOA|rcsb pdb:3HSM|rcsb pdb:3ILA|rcsb pdb:3J8H|rcsb pdb:3RQR|rcsb pdb:4ERT|rcsb pdb:4ESU|rcsb pdb:4ETT|go:"GO:0035381"(ATP-gated ion channel activity)|rcsb pdb:4ETU|rcsb pdb:4I0Y|rcsb pdb:4I1E|go:"GO:0042802"(identical protein binding)|rcsb pdb:4I2S|rcsb pdb:4I37|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|rcsb pdb:4I3N|rcsb pdb:4I6I|rcsb pdb:4I7I|rcsb pdb:4I8M|rcsb pdb:4I96|rcsb pdb:4P9J|rcsb pdb:4UWA|go:"GO:0044325"(transmembrane transporter binding)|rcsb pdb:4UWE|rcsb pdb:5C30|rcsb pdb:5GKY|rcsb pdb:5GKZ|rcsb pdb:5GL0|rcsb pdb:5GL1|rcsb pdb:5J8V|rcsb pdb:5T15|rcsb pdb:5T9M|rcsb pdb:5T9N|rcsb pdb:5T9R|rcsb pdb:5T9S|rcsb pdb:5T9V|rcsb pdb:5TA3|rcsb pdb:5TAL|rcsb pdb:5TAM|rcsb pdb:5TAN|rcsb pdb:5TAP|rcsb pdb:5TAQ|rcsb pdb:5TAS|rcsb pdb:5TAT|rcsb pdb:5TAU|rcsb pdb:5TAV|rcsb pdb:5TAW|rcsb pdb:5TAX|rcsb pdb:5TAY|rcsb pdb:5TAZ|rcsb pdb:5TB0|rcsb pdb:5TB1|rcsb pdb:5TB2|rcsb pdb:5TB3|rcsb pdb:5TB4|rcsb pdb:6FG3|rcsb pdb:6FOO|rcsb pdb:6M2W|rcsb pdb:6WOT|rcsb pdb:7CF9|refseq:NP_001095188.1|dip:DIP-41872N - - - figure legend:2 and table 2,3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2019/01/30 rogid:Ov9RnZkDk8++0ko2WdLrW7BJyts9031 rogid:QUlch7kTlopwGM10g+OXd4rODXo9986 intact-crc:79EF3EF44D7B88D0 false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) chebi:"CHEBI:8925" intact:EBI-6692507 intact:EBI-6857858 - psi-mi:ryanodine(display_short)|psi-mi:"CHEBI:8925"(display_long) psi-mi:ryr1_oncmy_protein(display_short)|psi-mi:EBI-6692507(display_long) psi-mi:"MI:0405"(competition binding) Qi et al. (1998) pubmed:9857007|imex:IM-26050 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:8022(oncmy)|taxid:8022("Oncorhynchus mykiss (Rainbow trout)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:1335"(HPIDb) intact:EBI-6857867|imex:IM-26050-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - - - - comment:Similar to O13054 figure legend:2 and table 2,3 and 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2013/04/29 2019/01/30 - - intact-crc:91CAB95AE1AA4135 false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)