#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O75663	uniprotkb:P63330	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	intact:EBI-397144|uniprotkb:O88591|uniprotkb:P13353|uniprotkb:Q5SNY5|ensembl:ENSMUSP00000020608	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:pp2aa_mouse(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673120|imex:IM-22136-1|mint:MINT-8434215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G|mint:MINT-8434217(identity)	refseq:NP_062284.1|ensembl:ENSMUSG00000020349(gene)|ensembl:ENSMUST00000020608(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P63330|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2995383|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-9648025|reactome:R-MMU-975957|mint:MINT-8434240(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f2a f2d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rogid:gpR5Fal3vi6O6cteeGwW72EuctY10090	intact-crc:9FB05E5DBC8F0EA6|rigid:P1EX/8gGr8AXGrWaeQnSJCILP/g	false	ha tag:?-?(MINT-8434245)	mutation disrupting interaction:307-307(MINT-8434735)|flag tag:?-?(MINT-8434241)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P63331	uniprotkb:Q76MZ3	intact:EBI-7050205|ensembl:ENSRNOP00000007621|ensembl:ENSRNOP00000071286|intact:MINT-199689|uniprotkb:O88591|uniprotkb:P13353	intact:EBI-400413|ensembl:ENSMUSP00000007708	psi-mi:pp2aa_rat(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short)	psi-mi:2aaa_mouse(display_long)|uniprotkb:Ppp2r1a(gene name)|psi-mi:Ppp2r1a(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673141|imex:IM-22136-2|mint:MINT-8434775	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008772116.1|ensembl:ENSRNOG00000005389(gene)|ensembl:ENSRNOG00000056485(gene)|ensembl:ENSRNOT00000007621(transcript)|ensembl:ENSRNOT00000079985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-RNO-1295596|reactome:R-RNO-141444|reactome:R-RNO-180024|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-198753|reactome:R-RNO-202670|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2995383|reactome:R-RNO-389513|reactome:R-RNO-4641262|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5675221|reactome:R-RNO-6804757|reactome:R-RNO-6811558|reactome:R-RNO-68877|reactome:R-RNO-69231|reactome:R-RNO-69273|reactome:R-RNO-9648025|reactome:R-RNO-975957|mint:P63331|reactome:R-RNO-113501|refseq:NP_058735.1|rgd:3380|mint:MINT-8434778(identity)	refseq:NP_058587.1|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:Q76MZ3|rcsb pdb:2IAE|rcsb pdb:2PF4|rcsb pdb:3FGA|rcsb pdb:6EF4|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2995383|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-8854518|reactome:R-MMU-9648025|reactome:R-MMU-975957|ensembl:ENSMUSG00000007564(gene)|ensembl:ENSMUST00000007708(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051232"(meiotic spindle elongation)|dip:DIP-29429N|mint:MINT-8434777(identity)	-	function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint	-	figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:gpR5Fal3vi6O6cteeGwW72EuctY10116	rogid:0tnO11U1SNOOT46j23f7dim8O8k10090	intact-crc:FC30896EBF91BB4B|rigid:r+8KUPz4nxtpVZ6Kd1DqdCNPzuI	false	flag tag:?-?(MINT-8434784)	ha tag:?-?(MINT-8434780)	-	-	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P63331	uniprotkb:P30153	intact:EBI-7050205|ensembl:ENSRNOP00000007621|ensembl:ENSRNOP00000071286|intact:MINT-199689|uniprotkb:O88591|uniprotkb:P13353	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:pp2aa_rat(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673175|imex:IM-22136-4|mint:MINT-8434801	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008772116.1|ensembl:ENSRNOG00000005389(gene)|ensembl:ENSRNOG00000056485(gene)|ensembl:ENSRNOT00000007621(transcript)|ensembl:ENSRNOT00000079985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-RNO-1295596|reactome:R-RNO-141444|reactome:R-RNO-180024|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-198753|reactome:R-RNO-202670|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2995383|reactome:R-RNO-389513|reactome:R-RNO-4641262|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5675221|reactome:R-RNO-6804757|reactome:R-RNO-6811558|reactome:R-RNO-68877|reactome:R-RNO-69231|reactome:R-RNO-69273|reactome:R-RNO-9648025|reactome:R-RNO-975957|mint:P63331|reactome:R-RNO-113501|refseq:NP_058735.1|rgd:3380|mint:MINT-8434804(identity)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N|mint:MINT-8434805(identity)	-	function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint	-	figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:gpR5Fal3vi6O6cteeGwW72EuctY10116	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:C4654FD7D8FB868A|rigid:skNwNQcVE47qpW8h0b3+ckEfMIQ	false	flag tag:?-?(MINT-8434807)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63331	uniprotkb:O75663	intact:EBI-7050205|ensembl:ENSRNOP00000007621|ensembl:ENSRNOP00000071286|intact:MINT-199689|uniprotkb:O88591|uniprotkb:P13353	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:pp2aa_rat(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673175|imex:IM-22136-4|mint:MINT-8434801	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008772116.1|ensembl:ENSRNOG00000005389(gene)|ensembl:ENSRNOG00000056485(gene)|ensembl:ENSRNOT00000007621(transcript)|ensembl:ENSRNOT00000079985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-RNO-1295596|reactome:R-RNO-141444|reactome:R-RNO-180024|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-198753|reactome:R-RNO-202670|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2995383|reactome:R-RNO-389513|reactome:R-RNO-4641262|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5675221|reactome:R-RNO-6804757|reactome:R-RNO-6811558|reactome:R-RNO-68877|reactome:R-RNO-69231|reactome:R-RNO-69273|reactome:R-RNO-9648025|reactome:R-RNO-975957|mint:P63331|reactome:R-RNO-113501|refseq:NP_058735.1|rgd:3380|mint:MINT-8434804(identity)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G|mint:MINT-8434803(identity)	-	function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint	-	figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:gpR5Fal3vi6O6cteeGwW72EuctY10116	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	intact-crc:C4654FD7D8FB868A|rigid:skNwNQcVE47qpW8h0b3+ckEfMIQ	false	flag tag:?-?(MINT-8434807)	ha tag:?-?(MINT-8434813)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P63331	uniprotkb:O75663	intact:EBI-7050205|ensembl:ENSRNOP00000007621|ensembl:ENSRNOP00000071286|intact:MINT-199689|uniprotkb:O88591|uniprotkb:P13353	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:pp2aa_rat(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673158|imex:IM-22136-3|mint:MINT-8434788	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008772116.1|ensembl:ENSRNOG00000005389(gene)|ensembl:ENSRNOG00000056485(gene)|ensembl:ENSRNOT00000007621(transcript)|ensembl:ENSRNOT00000079985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-RNO-1295596|reactome:R-RNO-141444|reactome:R-RNO-180024|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-198753|reactome:R-RNO-202670|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2995383|reactome:R-RNO-389513|reactome:R-RNO-4641262|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5675221|reactome:R-RNO-6804757|reactome:R-RNO-6811558|reactome:R-RNO-68877|reactome:R-RNO-69231|reactome:R-RNO-69273|reactome:R-RNO-9648025|reactome:R-RNO-975957|mint:P63331|reactome:R-RNO-113501|refseq:NP_058735.1|rgd:3380|mint:MINT-8434791(identity)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G|mint:MINT-8434790(identity)	-	function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint	-	figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:gpR5Fal3vi6O6cteeGwW72EuctY10116	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	intact-crc:72F826F855752970|rigid:SrpfMY0MtAerRbI4q4XgtuF7qvY	false	flag tag:?-?(MINT-8434797)	tandem tag:?-?(MINT-8434793)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P63331	uniprotkb:O75663	intact:EBI-7050205|ensembl:ENSRNOP00000007621|ensembl:ENSRNOP00000071286|intact:MINT-199689|uniprotkb:O88591|uniprotkb:P13353	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:pp2aa_rat(display_long)|uniprotkb:Ppp2ca(gene name)|psi-mi:Ppp2ca(display_short)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673195|imex:IM-22136-5|mint:MINT-8434817	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008772116.1|ensembl:ENSRNOG00000005389(gene)|ensembl:ENSRNOG00000056485(gene)|ensembl:ENSRNOT00000007621(transcript)|ensembl:ENSRNOT00000079985(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1990405"(protein antigen binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|reactome:R-RNO-1295596|reactome:R-RNO-141444|reactome:R-RNO-180024|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-198753|reactome:R-RNO-202670|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2995383|reactome:R-RNO-389513|reactome:R-RNO-4641262|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5675221|reactome:R-RNO-6804757|reactome:R-RNO-6811558|reactome:R-RNO-68877|reactome:R-RNO-69231|reactome:R-RNO-69273|reactome:R-RNO-9648025|reactome:R-RNO-975957|mint:P63331|reactome:R-RNO-113501|refseq:NP_058735.1|rgd:3380|mint:MINT-8434819(identity)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G|mint:MINT-8434823(identity)	-	function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint	-	figure legend:f4a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:gpR5Fal3vi6O6cteeGwW72EuctY10116	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	intact-crc:125C5228527EC7C9|rigid:SrpfMY0MtAerRbI4q4XgtuF7qvY	false	flag tag:?-?(MINT-8434820)	ha tag:?-?(MINT-8434824)|mutation disrupting interaction:71-71(MINT-8434829)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P78318	uniprotkb:P67775	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673247|imex:IM-22136-8|mint:MINT-8434766	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1|mint:MINT-8434770(identity)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N|mint:MINT-8434768(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f2c sf1b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:B44B6C56A9F1B2B1|rigid:ol5mQbq8IFEuUVHNJaVQdM5aZIc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P78318	uniprotkb:O75663	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673258|imex:IM-22136-9|mint:MINT-8434835	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1|mint:MINT-8434837(identity)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G|mint:MINT-8434839(identity)	-	-	-	figure legend:sf1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	intact-crc:E07573C2ACE643A3|rigid:VZzDswAF2NChxKjMBWqNyzuRDwk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P67775	uniprotkb:O75663	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673225|imex:IM-22136-6|mint:MINT-8434742	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N|mint:MINT-8434744(identity)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G|mint:MINT-8434745(identity)	-	-	-	figure legend:f2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	intact-crc:D359A61D2687706E|rigid:t4QCYvPsdEXTDWRZbBrSSD4xusk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P67775	uniprotkb:O75663	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673236|imex:IM-22136-7|mint:MINT-8434751	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N|mint:MINT-8434755(identity)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G|mint:MINT-8434753(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f2b f2c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	intact-crc:813C3565F53D4DA6|rigid:t4QCYvPsdEXTDWRZbBrSSD4xusk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O75663	uniprotkb:P78318	intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807	intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661	psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym)	psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nakashima et al. (2013)	mint:MINT-8434208|pubmed:23892082|imex:IM-22136	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8673269|imex:IM-22136-10|mint:MINT-8434844	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G|mint:MINT-8434846(identity)	refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1|mint:MINT-8434848(identity)	-	-	-	figure legend:sf1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2013/08/22	2014/10/16	rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606	rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606	intact-crc:D3E6EDE2ACE06B85|rigid:VZzDswAF2NChxKjMBWqNyzuRDwk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)