#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8N2Z9 uniprotkb:A8MT69 intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583 intact:EBI-5529694|uniprotkb:O00281|uniprotkb:O00282|uniprotkb:Q96DD4|uniprotkb:Q96F51|ensembl:ENSP00000376168 psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym) psi-mi:cenpx_human(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:FAAP10(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 2(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 2(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 10 kDa(gene name synonym)|uniprotkb:MHF2(gene name synonym)|uniprotkb:Retinoic acid-inducible gene D9 protein homolog(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Wang et al. (2013) mint:MINT-8434262|imex:IM-21318|pubmed:23886707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8670867|imex:IM-21318-1|mint:MINT-8434303 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025|mint:MINT-8434639(identity) refseq:NP_659435.2|refseq:NP_001257935.1|refseq:NP_001257936.1|refseq:NP_001317465.1|ensembl:ENSG00000169689(gene)|ensembl:ENST00000392359(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR018552|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-606279|reactome:R-HSA-6783310|mint:MINT-8434637(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" figure legend:f1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606 rogid:CwD7kVdQX6u8LJVlcqL/SbDxOg09606 intact-crc:63C78AA4993482A7|rigid:BV6PnUBcvAgw6NNDHbk9gpzXqno false - - 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N2Z9 uniprotkb:Q8IYD8 intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583 intact:EBI-3957237|ensembl:ENSP00000267430|uniprotkb:Q3YFH9|uniprotkb:Q8N9X6|uniprotkb:Q9HCH6|uniprotkb:B2RTQ9|intact:EBI-10977447|intact:EBI-14204029|intact:EBI-12869570 psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym) psi-mi:fancm_human(display_long)|uniprotkb:FANCM(gene name)|psi-mi:FANCM(display_short)|uniprotkb:KIAA1596(gene name synonym)|uniprotkb:ATP-dependent RNA helicase FANCM(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 250 kDa(gene name synonym)|uniprotkb:Protein Hef ortholog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Wang et al. (2013) mint:MINT-8434262|imex:IM-21318|pubmed:23886707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8670867|imex:IM-21318-1|mint:MINT-8434303 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025|mint:MINT-8434639(identity) ensembl:ENSG00000187790(gene)|ensembl:ENST00000267430(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0071821"(FANCM-MHF complex)|go:"GO:0071932"(replication fork reversal)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031879|interpro:IPR039686|interpro:IPR044749|mint:Q8IYD8|rcsb pdb:4DAY|rcsb pdb:4DRB|rcsb pdb:4E45|rcsb pdb:4M6W|reactome:R-HSA-6783310|rcsb pdb:4BXO|refseq:NP_001295062.1|refseq:NP_001295063.1|refseq:NP_065988.1|dip:DIP-43972N|mint:MINT-8434305(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 1.0" figure legend:f1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606 rogid:APU9Ya2dfdgJgIwZPl5Z8/QMbgM9606 intact-crc:63C78AA4993482A7|rigid:BV6PnUBcvAgw6NNDHbk9gpzXqno false - binding-associated region:661-800(MINT-8434641) 2 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A8MT69 uniprotkb:Q8N2Z9 intact:EBI-5529694|uniprotkb:O00281|uniprotkb:O00282|uniprotkb:Q96DD4|uniprotkb:Q96F51|ensembl:ENSP00000376168 intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583 psi-mi:cenpx_human(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:FAAP10(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 2(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 2(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 10 kDa(gene name synonym)|uniprotkb:MHF2(gene name synonym)|uniprotkb:Retinoic acid-inducible gene D9 protein homolog(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein homolog(gene name synonym) psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Wang et al. (2013) mint:MINT-8434262|imex:IM-21318|pubmed:23886707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8670887|imex:IM-21318-2|mint:MINT-8434649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659435.2|refseq:NP_001257935.1|refseq:NP_001257936.1|refseq:NP_001317465.1|ensembl:ENSG00000169689(gene)|ensembl:ENST00000392359(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR018552|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-606279|reactome:R-HSA-6783310|mint:MINT-8434657(identity) refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025|mint:MINT-8434655(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" figure legend:f1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:CwD7kVdQX6u8LJVlcqL/SbDxOg09606 rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606 intact-crc:00721B84CFEBD4F5|rigid:pIs6AihU6lR7jzlIocKUJFLwLJQ false - - 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N2Z9 uniprotkb:A8MT69 intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583 intact:EBI-5529694|uniprotkb:O00281|uniprotkb:O00282|uniprotkb:Q96DD4|uniprotkb:Q96F51|ensembl:ENSP00000376168 psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym) psi-mi:cenpx_human(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:FAAP10(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 2(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 2(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 10 kDa(gene name synonym)|uniprotkb:MHF2(gene name synonym)|uniprotkb:Retinoic acid-inducible gene D9 protein homolog(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein homolog(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Wang et al. (2013) mint:MINT-8434262|imex:IM-21318|pubmed:23886707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8670909|imex:IM-21318-3|mint:MINT-8434669 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025|mint:MINT-8434673(identity) refseq:NP_659435.2|refseq:NP_001257935.1|refseq:NP_001257936.1|refseq:NP_001317465.1|ensembl:ENSG00000169689(gene)|ensembl:ENST00000392359(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR018552|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-606279|reactome:R-HSA-6783310|mint:MINT-8434671(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" comment:homomint|comment:mint|figure legend:f2b t1 f4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606 rogid:CwD7kVdQX6u8LJVlcqL/SbDxOg09606 intact-crc:6A07C1467E924F71|rigid:BV6PnUBcvAgw6NNDHbk9gpzXqno false - - 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N2Z9 uniprotkb:Q8IYD8 intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583 intact:EBI-3957237|ensembl:ENSP00000267430|uniprotkb:Q3YFH9|uniprotkb:Q8N9X6|uniprotkb:Q9HCH6|uniprotkb:B2RTQ9|intact:EBI-10977447|intact:EBI-14204029|intact:EBI-12869570 psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym) psi-mi:fancm_human(display_long)|uniprotkb:FANCM(gene name)|psi-mi:FANCM(display_short)|uniprotkb:KIAA1596(gene name synonym)|uniprotkb:ATP-dependent RNA helicase FANCM(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 250 kDa(gene name synonym)|uniprotkb:Protein Hef ortholog(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Wang et al. (2013) mint:MINT-8434262|imex:IM-21318|pubmed:23886707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8670909|imex:IM-21318-3|mint:MINT-8434669 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025|mint:MINT-8434673(identity) ensembl:ENSG00000187790(gene)|ensembl:ENST00000267430(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0071821"(FANCM-MHF complex)|go:"GO:0071932"(replication fork reversal)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031879|interpro:IPR039686|interpro:IPR044749|mint:Q8IYD8|rcsb pdb:4DAY|rcsb pdb:4DRB|rcsb pdb:4E45|rcsb pdb:4M6W|reactome:R-HSA-6783310|rcsb pdb:4BXO|refseq:NP_001295062.1|refseq:NP_001295063.1|refseq:NP_065988.1|dip:DIP-43972N|mint:MINT-8434675(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint|figure legend:f2b t1 f4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606 rogid:APU9Ya2dfdgJgIwZPl5Z8/QMbgM9606 intact-crc:6A07C1467E924F71|rigid:BV6PnUBcvAgw6NNDHbk9gpzXqno false - binding-associated region:661-800(MINT-8434676) 2 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N2Z9 uniprotkb:A8MT69 intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583 intact:EBI-5529694|uniprotkb:O00281|uniprotkb:O00282|uniprotkb:Q96DD4|uniprotkb:Q96F51|ensembl:ENSP00000376168 psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym) psi-mi:cenpx_human(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:FAAP10(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 2(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 2(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 10 kDa(gene name synonym)|uniprotkb:MHF2(gene name synonym)|uniprotkb:Retinoic acid-inducible gene D9 protein homolog(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein homolog(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Wang et al. (2013) mint:MINT-8434262|imex:IM-21318|pubmed:23886707 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8670929|imex:IM-21318-4|mint:MINT-8434686 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025|mint:MINT-8434688(identity) refseq:NP_659435.2|refseq:NP_001257935.1|refseq:NP_001257936.1|refseq:NP_001317465.1|ensembl:ENSG00000169689(gene)|ensembl:ENST00000392359(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR018552|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-606279|reactome:R-HSA-6783310|mint:MINT-8434690(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" comment:homomint|comment:mint|figure legend:f2a t1 f4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606 rogid:CwD7kVdQX6u8LJVlcqL/SbDxOg09606 intact-crc:43621BFE81F9DA28|rigid:pIs6AihU6lR7jzlIocKUJFLwLJQ false - - 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)