#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q45666 uniprotkb:P12425 intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188 intact:EBI-6402863|ensemblbacteria:CAB13630 psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym) psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Fedorova et al. (2013) mint:MINT-8416514|mint:d-12-01944r2|pubmed:23535029 taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8507036|mint:MINT-8416519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8416521(identity) ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8416522(identity) - comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA crc64:83A5657CE1388AB0 comment:mint|figure legend:f6 sf3 taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/12 2014/10/16 rogid:3loDv98VplHW96s2wkpgsgj0CE8224308 rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308 intact-crc:F26FF6BA949FEC4C|rigid:XIgvV+aZdlViw2UBOXhMQ6I9q88 false binding-associated region:75-110(MINT-8416528)|his tag:?-?(MINT-8416525) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q45666 uniprotkb:P12425 intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188 intact:EBI-6402863|ensemblbacteria:CAB13630 psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym) psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fedorova et al. (2013) mint:MINT-8416514|mint:d-12-01944r2|pubmed:23535029 taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8507077|mint:MINT-8416560 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8416564(identity) ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8416562(identity) - comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA crc64:83A5657CE1388AB0 figure legend:f5|comment:mint taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) - 2013/03/12 2014/10/16 rogid:3loDv98VplHW96s2wkpgsgj0CE8224308 rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308 intact-crc:37E62A3A873618B2|rigid:XIgvV+aZdlViw2UBOXhMQ6I9q88 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q45666 uniprotkb:P40758 intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188 intact:EBI-8507093|intact:MINT-8145066|uniprotkb:O87101|ensemblbacteria:CAB12038 psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym) psi-mi:glnk_bacsu(display_long)|uniprotkb:glnK(gene name)|psi-mi:glnK(display_short)|uniprotkb:ycbA(gene name synonym)|uniprotkb:yzgA(gene name synonym)|uniprotkb:BSU02440(locus name)|uniprotkb:nrgB(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fedorova et al. (2013) mint:MINT-8416514|mint:d-12-01944r2|pubmed:23535029 taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8507088|mint:MINT-8416576 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8416578(identity) refseq:WP_010886394.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|refseq:NP_388126.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|mint:P40758|interpro:IPR036890|ensemblbacteria:BSU_02440(gene)|ensemblbacteria:CAB12038(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005524"(ATP binding)|mint:MINT-8416580(identity) - comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA comment:mint figure legend:f5|comment:mint taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) - 2013/03/12 2014/10/16 rogid:3loDv98VplHW96s2wkpgsgj0CE8224308 rogid:0Edtkoa0bNGzkAYyu4x1Pz8spus224308 intact-crc:C51020DA6CABC7D1|rigid:gwcZtlxdDsLMD+QzarHhXzrR3xY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q45666 uniprotkb:P12425 intact:EBI-8507041|intact:MINT-224384|ensemblbacteria:CAB13188 intact:EBI-6402863|ensemblbacteria:CAB13630 psi-mi:tnra_bacsu(display_long)|uniprotkb:tnrA(gene name)|psi-mi:tnrA(display_short)|uniprotkb:scgR(gene name synonym)|uniprotkb:BSU13310(locus name)|uniprotkb:Transcriptional nitrogen regulatory protein A(gene name synonym) psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short) psi-mi:"MI:0096"(pull down) Fedorova et al. (2013) mint:MINT-8416514|mint:d-12-01944r2|pubmed:23535029 taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8507126|mint:MINT-8416587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003232541.1|refseq:NP_389214.1|interpro:IPR009061(Putative DNA binding)|mint:Q45666|ensemblbacteria:BSU_13310(gene)|ensemblbacteria:CAB13188(transcript)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0090294"(nitrogen catabolite activation of transcription)|rcsb pdb:4S0R|interpro:IPR000551(Bacterial regulatory protein, MerR)|mint:MINT-8416589(identity) ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8416591(identity) - comment:mint|function:Regulator of transcription that activates or represses many genes during nitrogen-limited growth; among others, it activates nrgAB, nasABCDE, gabP, and represses glnRA crc64:83A5657CE1388AB0 figure legend:sf1|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/12 2014/10/16 rogid:3loDv98VplHW96s2wkpgsgj0CE8224308 rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308 intact-crc:A8C61E5E1F85AFDC|rigid:XIgvV+aZdlViw2UBOXhMQ6I9q88 false his tag:?-?(MINT-8416599)|binding-associated region:105-110(MINT-8416601) tag:?-?(MINT-8416596) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P40758 uniprotkb:P12425 intact:EBI-8507093|intact:MINT-8145066|uniprotkb:O87101|ensemblbacteria:CAB12038 intact:EBI-6402863|ensemblbacteria:CAB13630 psi-mi:glnk_bacsu(display_long)|uniprotkb:glnK(gene name)|psi-mi:glnK(display_short)|uniprotkb:ycbA(gene name synonym)|uniprotkb:yzgA(gene name synonym)|uniprotkb:BSU02440(locus name)|uniprotkb:nrgB(gene name synonym) psi-mi:gln1a_bacsu(display_long)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:BSU17460(locus name)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:glnA(gene name)|psi-mi:glnA(display_short) psi-mi:"MI:0096"(pull down) Fedorova et al. (2013) mint:MINT-8416514|mint:d-12-01944r2|pubmed:23535029 taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) taxid:224308(bacsu)|taxid:224308(Bacillus subtilis) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8507145|mint:MINT-8416604 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010886394.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|refseq:NP_388126.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|mint:P40758|interpro:IPR036890|ensemblbacteria:BSU_02440(gene)|ensemblbacteria:CAB12038(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005524"(ATP binding)|mint:MINT-8416610(identity) ensemblbacteria:BSU_17460(gene)|ensemblbacteria:CAB13630(transcript)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0043562"(cellular response to nitrogen levels)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070406"(glutamine binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904797"(negative regulation of core promoter binding)|interpro:IPR001637(Glutamine synthetase class-I, adenylation site)|interpro:IPR004809(Glutamine synthetase type I)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|rcsb pdb:2FWX|rcsb pdb:4LNF|rcsb pdb:4LNI|rcsb pdb:4LNK|rcsb pdb:4LNN|rcsb pdb:4LNO|rcsb pdb:4S0R|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|mint:P12425|refseq:NP_389628.1|refseq:WP_003231737.1|dip:DIP-29670N|mint:MINT-8416606(identity) - comment:mint crc64:83A5657CE1388AB0 figure legend:sf1|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/03/12 2014/10/16 rogid:0Edtkoa0bNGzkAYyu4x1Pz8spus224308 rogid:3GNZhSZdC/UMI1QV+D1M9Mpltdk224308 intact-crc:7B69AB06C24CF4AF|rigid:fvcVdxdPDmyhk5BZOB78sFaqDYc false his tag:?-?(MINT-8416613)|binding-associated region:371-410(MINT-8416611) tag:?-?(MINT-8416607) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot)