#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9FR53 uniprotkb:P42818 intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 intact:EBI-8107038|intact:MINT-8050626|uniprotkb:Q8LFC1|ensemblplants:AT3G08730.1|ensemblplants:AT3G08730.2 psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:kpk1_arath(display_long)|uniprotkb:Ribosomal-protein S6 kinase homolog 1(gene name synonym)|uniprotkb:S6K1(gene name synonym)|uniprotkb:F17O14.20(orf name)|uniprotkb:At3g08730(locus name)|uniprotkb:ATPK1(gene name)|psi-mi:ATPK1(display_short)|uniprotkb:ATPK6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792715|imex:IM-21549-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 go:"GO:0009409"(response to cold)|refseq:NP_001326081.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_187485.1|interpro:IPR017892|mint:P42818|interpro:IPR000961(Protein kinase, C-terminal)|ensemblplants:AT3G08730(gene)|ensemblplants:AT3G08730.1(transcript)|ensemblplants:AT3G08730.2(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" - - comment:mint figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 rogid:w7t4MHgZQDU4WhS0EKEqYWg2Gdo3702 intact-crc:FE22A740D29545A6|rigid:fU6Dxzz8Wj+ImgKkOgT23AYz3yI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9FR53 uniprotkb:O49160 intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 intact:EBI-1635551|uniprotkb:Q9LYM6|ensemblplants:AT3G56150.1|ensemblplants:AT3G56150.2 psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:eif3c_arath(display_long)|uniprotkb:TIF3C1(gene name)|psi-mi:TIF3C1(display_short)|uniprotkb:F18O21_110(orf name)|uniprotkb:At3g56150(locus name)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792715|imex:IM-21549-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 refseq:NP_001190102.1|refseq:NP_191174.1|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:O49160|ensemblplants:AT3G56150(gene)|ensemblplants:AT3G56150.1(transcript)|ensemblplants:AT3G56150.2(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex) - - - figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 rogid:laFzSPmmN9/qmho9rBOCeb6oREQ3702 intact-crc:FE22A740D29545A6|rigid:fU6Dxzz8Wj+ImgKkOgT23AYz3yI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42818 uniprotkb:O49160 intact:EBI-8107038|intact:MINT-8050626|uniprotkb:Q8LFC1|ensemblplants:AT3G08730.1|ensemblplants:AT3G08730.2 intact:EBI-1635551|uniprotkb:Q9LYM6|ensemblplants:AT3G56150.1|ensemblplants:AT3G56150.2 psi-mi:kpk1_arath(display_long)|uniprotkb:Ribosomal-protein S6 kinase homolog 1(gene name synonym)|uniprotkb:S6K1(gene name synonym)|uniprotkb:F17O14.20(orf name)|uniprotkb:At3g08730(locus name)|uniprotkb:ATPK1(gene name)|psi-mi:ATPK1(display_short)|uniprotkb:ATPK6(gene name synonym) psi-mi:eif3c_arath(display_long)|uniprotkb:TIF3C1(gene name)|psi-mi:TIF3C1(display_short)|uniprotkb:F18O21_110(orf name)|uniprotkb:At3g56150(locus name)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8792730|imex:IM-21549-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009409"(response to cold)|refseq:NP_001326081.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_187485.1|interpro:IPR017892|mint:P42818|interpro:IPR000961(Protein kinase, C-terminal)|ensemblplants:AT3G08730(gene)|ensemblplants:AT3G08730.1(transcript)|ensemblplants:AT3G08730.2(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001190102.1|refseq:NP_191174.1|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:O49160|ensemblplants:AT3G56150(gene)|ensemblplants:AT3G56150.1(transcript)|ensemblplants:AT3G56150.2(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex) - comment:mint - figure legend:f1c|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:w7t4MHgZQDU4WhS0EKEqYWg2Gdo3702 rogid:laFzSPmmN9/qmho9rBOCeb6oREQ3702 intact-crc:B340CA5FC3D525B2|rigid:2lqBDxZAXkLBtUBIT6Hzvv6pJIc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42818 uniprotkb:Q9FR53 intact:EBI-8107038|intact:MINT-8050626|uniprotkb:Q8LFC1|ensemblplants:AT3G08730.1|ensemblplants:AT3G08730.2 intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 psi-mi:kpk1_arath(display_long)|uniprotkb:Ribosomal-protein S6 kinase homolog 1(gene name synonym)|uniprotkb:S6K1(gene name synonym)|uniprotkb:F17O14.20(orf name)|uniprotkb:At3g08730(locus name)|uniprotkb:ATPK1(gene name)|psi-mi:ATPK1(display_short)|uniprotkb:ATPK6(gene name synonym) psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792760|imex:IM-21549-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009409"(response to cold)|refseq:NP_001326081.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_187485.1|interpro:IPR017892|mint:P42818|interpro:IPR000961(Protein kinase, C-terminal)|ensemblplants:AT3G08730(gene)|ensemblplants:AT3G08730.1(transcript)|ensemblplants:AT3G08730.2(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 - comment:mint - figure legend:f6h|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:w7t4MHgZQDU4WhS0EKEqYWg2Gdo3702 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 intact-crc:5FE5DFA6C5CC8DE1|rigid:mIHi2cjpoUbQ6qQX/a2wT3UWYbo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42818 uniprotkb:Q9C5Z2 intact:EBI-8107038|intact:MINT-8050626|uniprotkb:Q8LFC1|ensemblplants:AT3G08730.1|ensemblplants:AT3G08730.2 intact:EBI-3387106|ensemblplants:AT1G10840.1|uniprotkb:Q9SAB9|uniprotkb:F4I5Y8 psi-mi:kpk1_arath(display_long)|uniprotkb:Ribosomal-protein S6 kinase homolog 1(gene name synonym)|uniprotkb:S6K1(gene name synonym)|uniprotkb:F17O14.20(orf name)|uniprotkb:At3g08730(locus name)|uniprotkb:ATPK1(gene name)|psi-mi:ATPK1(display_short)|uniprotkb:ATPK6(gene name synonym) psi-mi:eif3h_arath(display_long)|uniprotkb:TIF3H1(gene name)|psi-mi:TIF3H1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p38 subunit(gene name synonym)|uniprotkb:T16B5.2(orf name)|uniprotkb:At1g10840(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792760|imex:IM-21549-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009409"(response to cold)|refseq:NP_001326081.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_187485.1|interpro:IPR017892|mint:P42818|interpro:IPR000961(Protein kinase, C-terminal)|ensemblplants:AT3G08730(gene)|ensemblplants:AT3G08730.1(transcript)|ensemblplants:AT3G08730.2(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensemblplants:AT1G10840(gene)|ensemblplants:AT1G10840.1(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009733"(response to auxin)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009744"(response to sucrose)|go:"GO:0009749"(response to glucose)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034286"(response to maltose)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0070122"(isopeptidase activity)|refseq:NP_563880.1|interpro:IPR037518|interpro:IPR000555(Mov34/MPN/PAD-1)|refseq:NP_973808.1|mint:Q9C5Z2|interpro:IPR027524 - comment:mint - figure legend:f6h|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:w7t4MHgZQDU4WhS0EKEqYWg2Gdo3702 rogid:oj1OwZDF7WLF4beHxkMKhxTmfOo3702 intact-crc:5FE5DFA6C5CC8DE1|rigid:mIHi2cjpoUbQ6qQX/a2wT3UWYbo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O49160 uniprotkb:Q9FR53 intact:EBI-1635551|uniprotkb:Q9LYM6|ensemblplants:AT3G56150.1|ensemblplants:AT3G56150.2 intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 psi-mi:eif3c_arath(display_long)|uniprotkb:TIF3C1(gene name)|psi-mi:TIF3C1(display_short)|uniprotkb:F18O21_110(orf name)|uniprotkb:At3g56150(locus name)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym) psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8792723|imex:IM-21549-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190102.1|refseq:NP_191174.1|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:O49160|ensemblplants:AT3G56150(gene)|ensemblplants:AT3G56150.1(transcript)|ensemblplants:AT3G56150.2(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex) refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 - - - figure legend:f1c|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:laFzSPmmN9/qmho9rBOCeb6oREQ3702 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 intact-crc:88FF54885B038843|rigid:C4KFyp24xNaJlQT6JoNc8OADe1E false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9FR53 uniprotkb:P42818 intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 intact:EBI-8107038|intact:MINT-8050626|uniprotkb:Q8LFC1|ensemblplants:AT3G08730.1|ensemblplants:AT3G08730.2 psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:kpk1_arath(display_long)|uniprotkb:Ribosomal-protein S6 kinase homolog 1(gene name synonym)|uniprotkb:S6K1(gene name synonym)|uniprotkb:F17O14.20(orf name)|uniprotkb:At3g08730(locus name)|uniprotkb:ATPK1(gene name)|psi-mi:ATPK1(display_short)|uniprotkb:ATPK6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792754|imex:IM-21549-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 go:"GO:0009409"(response to cold)|refseq:NP_001326081.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_187485.1|interpro:IPR017892|mint:P42818|interpro:IPR000961(Protein kinase, C-terminal)|ensemblplants:AT3G08730(gene)|ensemblplants:AT3G08730.1(transcript)|ensemblplants:AT3G08730.2(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" - - comment:mint figure legend:f6h|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 rogid:w7t4MHgZQDU4WhS0EKEqYWg2Gdo3702 intact-crc:0D5BB163F898A823|rigid:mIHi2cjpoUbQ6qQX/a2wT3UWYbo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9FR53 uniprotkb:Q9C5Z2 intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 intact:EBI-3387106|ensemblplants:AT1G10840.1|uniprotkb:Q9SAB9|uniprotkb:F4I5Y8 psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:eif3h_arath(display_long)|uniprotkb:TIF3H1(gene name)|psi-mi:TIF3H1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p38 subunit(gene name synonym)|uniprotkb:T16B5.2(orf name)|uniprotkb:At1g10840(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792754|imex:IM-21549-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 ensemblplants:AT1G10840(gene)|ensemblplants:AT1G10840.1(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009733"(response to auxin)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009744"(response to sucrose)|go:"GO:0009749"(response to glucose)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034286"(response to maltose)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0070122"(isopeptidase activity)|refseq:NP_563880.1|interpro:IPR037518|interpro:IPR000555(Mov34/MPN/PAD-1)|refseq:NP_973808.1|mint:Q9C5Z2|interpro:IPR027524 - - - figure legend:f6h|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 rogid:oj1OwZDF7WLF4beHxkMKhxTmfOo3702 intact-crc:0D5BB163F898A823|rigid:mIHi2cjpoUbQ6qQX/a2wT3UWYbo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9C5Z2 uniprotkb:P42818 intact:EBI-3387106|ensemblplants:AT1G10840.1|uniprotkb:Q9SAB9|uniprotkb:F4I5Y8 intact:EBI-8107038|intact:MINT-8050626|uniprotkb:Q8LFC1|ensemblplants:AT3G08730.1|ensemblplants:AT3G08730.2 psi-mi:eif3h_arath(display_long)|uniprotkb:TIF3H1(gene name)|psi-mi:TIF3H1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p38 subunit(gene name synonym)|uniprotkb:T16B5.2(orf name)|uniprotkb:At1g10840(locus name) psi-mi:kpk1_arath(display_long)|uniprotkb:Ribosomal-protein S6 kinase homolog 1(gene name synonym)|uniprotkb:S6K1(gene name synonym)|uniprotkb:F17O14.20(orf name)|uniprotkb:At3g08730(locus name)|uniprotkb:ATPK1(gene name)|psi-mi:ATPK1(display_short)|uniprotkb:ATPK6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792747|imex:IM-21549-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblplants:AT1G10840(gene)|ensemblplants:AT1G10840.1(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009733"(response to auxin)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009744"(response to sucrose)|go:"GO:0009749"(response to glucose)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034286"(response to maltose)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0070122"(isopeptidase activity)|refseq:NP_563880.1|interpro:IPR037518|interpro:IPR000555(Mov34/MPN/PAD-1)|refseq:NP_973808.1|mint:Q9C5Z2|interpro:IPR027524 go:"GO:0009409"(response to cold)|refseq:NP_001326081.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_187485.1|interpro:IPR017892|mint:P42818|interpro:IPR000961(Protein kinase, C-terminal)|ensemblplants:AT3G08730(gene)|ensemblplants:AT3G08730.1(transcript)|ensemblplants:AT3G08730.2(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" - - comment:mint figure legend:f6h|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:oj1OwZDF7WLF4beHxkMKhxTmfOo3702 rogid:w7t4MHgZQDU4WhS0EKEqYWg2Gdo3702 intact-crc:871A49413A6D6888|rigid:mIHi2cjpoUbQ6qQX/a2wT3UWYbo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9C5Z2 uniprotkb:Q9FR53 intact:EBI-3387106|ensemblplants:AT1G10840.1|uniprotkb:Q9SAB9|uniprotkb:F4I5Y8 intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 psi-mi:eif3h_arath(display_long)|uniprotkb:TIF3H1(gene name)|psi-mi:TIF3H1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p38 subunit(gene name synonym)|uniprotkb:T16B5.2(orf name)|uniprotkb:At1g10840(locus name) psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792747|imex:IM-21549-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblplants:AT1G10840(gene)|ensemblplants:AT1G10840.1(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009733"(response to auxin)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009744"(response to sucrose)|go:"GO:0009749"(response to glucose)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034286"(response to maltose)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0070122"(isopeptidase activity)|refseq:NP_563880.1|interpro:IPR037518|interpro:IPR000555(Mov34/MPN/PAD-1)|refseq:NP_973808.1|mint:Q9C5Z2|interpro:IPR027524 refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 - - - figure legend:f6h|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:oj1OwZDF7WLF4beHxkMKhxTmfOo3702 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 intact-crc:871A49413A6D6888|rigid:mIHi2cjpoUbQ6qQX/a2wT3UWYbo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O49160 uniprotkb:P42818 intact:EBI-1635551|uniprotkb:Q9LYM6|ensemblplants:AT3G56150.1|ensemblplants:AT3G56150.2 intact:EBI-8107038|intact:MINT-8050626|uniprotkb:Q8LFC1|ensemblplants:AT3G08730.1|ensemblplants:AT3G08730.2 psi-mi:eif3c_arath(display_long)|uniprotkb:TIF3C1(gene name)|psi-mi:TIF3C1(display_short)|uniprotkb:F18O21_110(orf name)|uniprotkb:At3g56150(locus name)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym) psi-mi:kpk1_arath(display_long)|uniprotkb:Ribosomal-protein S6 kinase homolog 1(gene name synonym)|uniprotkb:S6K1(gene name synonym)|uniprotkb:F17O14.20(orf name)|uniprotkb:At3g08730(locus name)|uniprotkb:ATPK1(gene name)|psi-mi:ATPK1(display_short)|uniprotkb:ATPK6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792710|imex:IM-21549-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190102.1|refseq:NP_191174.1|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:O49160|ensemblplants:AT3G56150(gene)|ensemblplants:AT3G56150.1(transcript)|ensemblplants:AT3G56150.2(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex) go:"GO:0009409"(response to cold)|refseq:NP_001326081.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_187485.1|interpro:IPR017892|mint:P42818|interpro:IPR000961(Protein kinase, C-terminal)|ensemblplants:AT3G08730(gene)|ensemblplants:AT3G08730.1(transcript)|ensemblplants:AT3G08730.2(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" - - comment:mint figure legend:f1a f1c|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:laFzSPmmN9/qmho9rBOCeb6oREQ3702 rogid:w7t4MHgZQDU4WhS0EKEqYWg2Gdo3702 intact-crc:F62A63AEF7F4EB34|rigid:fU6Dxzz8Wj+ImgKkOgT23AYz3yI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O49160 uniprotkb:Q9FR53 intact:EBI-1635551|uniprotkb:Q9LYM6|ensemblplants:AT3G56150.1|ensemblplants:AT3G56150.2 intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 psi-mi:eif3c_arath(display_long)|uniprotkb:TIF3C1(gene name)|psi-mi:TIF3C1(display_short)|uniprotkb:F18O21_110(orf name)|uniprotkb:At3g56150(locus name)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:p105(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym) psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8792710|imex:IM-21549-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190102.1|refseq:NP_191174.1|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:O49160|ensemblplants:AT3G56150(gene)|ensemblplants:AT3G56150.1(transcript)|ensemblplants:AT3G56150.2(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex) refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 - - - figure legend:f1a f1c|comment:"TOR was present in eIF3c immunoprecipitates only when suspension cultures were treated with auxin (Figure 1C). In contrast, S6K1 accumulated in the eIF3c pellet after a 6h incubation with Torin-1, but no S6K1 precipitation was seen 6 h after NAA treatment. Overall, these results suggest that eIF3 associates with S6K1 upon Torin-1 treatment, and with TOR in the presence of auxin."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath-cell-culture)|taxid:3702(Arabidopsis thaliana cell culture) - 2013/10/10 2014/10/16 rogid:laFzSPmmN9/qmho9rBOCeb6oREQ3702 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 intact-crc:F62A63AEF7F4EB34|rigid:fU6Dxzz8Wj+ImgKkOgT23AYz3yI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42818 uniprotkb:Q9C5Z2 intact:EBI-8107038|intact:MINT-8050626|uniprotkb:Q8LFC1|ensemblplants:AT3G08730.1|ensemblplants:AT3G08730.2 intact:EBI-3387106|ensemblplants:AT1G10840.1|uniprotkb:Q9SAB9|uniprotkb:F4I5Y8 psi-mi:kpk1_arath(display_long)|uniprotkb:Ribosomal-protein S6 kinase homolog 1(gene name synonym)|uniprotkb:S6K1(gene name synonym)|uniprotkb:F17O14.20(orf name)|uniprotkb:At3g08730(locus name)|uniprotkb:ATPK1(gene name)|psi-mi:ATPK1(display_short)|uniprotkb:ATPK6(gene name synonym) psi-mi:eif3h_arath(display_long)|uniprotkb:TIF3H1(gene name)|psi-mi:TIF3H1(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p38 subunit(gene name synonym)|uniprotkb:T16B5.2(orf name)|uniprotkb:At1g10840(locus name) psi-mi:"MI:0018"(two hybrid) Schepetilnikov et al. (2013) pubmed:23524850|imex:IM-21549 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8792797|imex:IM-21549-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009409"(response to cold)|refseq:NP_001326081.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|refseq:NP_187485.1|interpro:IPR017892|mint:P42818|interpro:IPR000961(Protein kinase, C-terminal)|ensemblplants:AT3G08730(gene)|ensemblplants:AT3G08730.1(transcript)|ensemblplants:AT3G08730.2(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensemblplants:AT1G10840(gene)|ensemblplants:AT1G10840.1(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009733"(response to auxin)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009738"(abscisic acid-activated signaling pathway)|go:"GO:0009744"(response to sucrose)|go:"GO:0009749"(response to glucose)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034286"(response to maltose)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0070122"(isopeptidase activity)|refseq:NP_563880.1|interpro:IPR037518|interpro:IPR000555(Mov34/MPN/PAD-1)|refseq:NP_973808.1|mint:Q9C5Z2|interpro:IPR027524 - comment:mint - figure legend:sf6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/10/10 2014/10/16 rogid:w7t4MHgZQDU4WhS0EKEqYWg2Gdo3702 rogid:oj1OwZDF7WLF4beHxkMKhxTmfOo3702 intact-crc:941EB7AE1B1EDA58|rigid:hbCsSkLHJLFAYGuL64cjfMLghXM false fusion protein:?-?|binding-associated region:1-465 binding-associated region:1-337|fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)