#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9U787 uniprotkb:Q9U787 intact:EBI-8002851|intact:MINT-8387804 intact:EBI-8002851|intact:MINT-8387804 psi-mi:q9u787_drome(display_long)|uniprotkb:Drep2(gene name)|psi-mi:Drep2(display_short)|uniprotkb:Drep-2(gene name synonym)|uniprotkb:Rep2(gene name synonym)|uniprotkb:drep2(gene name synonym)|uniprotkb:CG1975(orf name) psi-mi:q9u787_drome(display_long)|uniprotkb:Drep2(gene name)|psi-mi:Drep2(display_short)|uniprotkb:Drep-2(gene name synonym)|uniprotkb:Rep2(gene name synonym)|uniprotkb:drep2(gene name synonym)|uniprotkb:CG1975(orf name) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2013) mint:MINT-8414264|mint:d-13-00073r1|pubmed:23485826 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504909|mint:MINT-8414287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028408|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|mint:Q9U787|mint:MINT-8414295(identity) flybase:FBgn0028408|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|mint:Q9U787|mint:MINT-8414295(identity) - comment:mint|comment:"Stoichiometry: 8.0" comment:mint|comment:"Stoichiometry: 8.0" figure legend:f2|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/18 2014/10/16 rogid:xaXIToNPPDUaeY1dUv+ViY1spF47227 rogid:xaXIToNPPDUaeY1dUv+ViY1spF47227 intact-crc:BC58697E4E84C0F5|rigid:4CGfXil86v52twjM2ikdzDT/WAU false binding-associated region:1-84(MINT-8414297) binding-associated region:1-84(MINT-8414297) 8 0 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9U787 uniprotkb:O61464 intact:EBI-8002851|intact:MINT-8387804 intact:EBI-870636 psi-mi:q9u787_drome(display_long)|uniprotkb:Drep2(gene name)|psi-mi:Drep2(display_short)|uniprotkb:Drep-2(gene name synonym)|uniprotkb:Rep2(gene name synonym)|uniprotkb:drep2(gene name synonym)|uniprotkb:CG1975(orf name) psi-mi:o61464_drome(display_long)|uniprotkb:Drep1(gene name)|psi-mi:Drep1(display_short)|uniprotkb:Drep-1(gene name synonym)|uniprotkb:Rep1(gene name synonym)|uniprotkb:drep1(gene name synonym)|uniprotkb:CG8357(orf name) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2013) mint:MINT-8414264|mint:d-13-00073r1|pubmed:23485826 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504888|mint:MINT-8414282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028408|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|mint:Q9U787|mint:MINT-8414284(identity) flybase:FBgn0024732|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|mint:O61464|mint:MINT-8414285(identity) - comment:mint - figure legend:f2|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/18 2014/10/16 rogid:xaXIToNPPDUaeY1dUv+ViY1spF47227 rogid:blDkwfR4tiQTHQ5/vHJGMLpbjk87227 intact-crc:29B78DBD6817224C|rigid:qqeOQ6zBxqWPz7WYx55xIOTg/1s false mutation disrupting interaction:40-40(MINT-8414323)|binding-associated region:1-84(MINT-8414321) binding-associated region:1-90(MINT-8414328) - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9U787 uniprotkb:Q0E9B7 intact:EBI-8002851|intact:MINT-8387804 intact:EBI-97031|ensemblmetazoa:FBpp0087087|ensemblmetazoa:FBpp0087088 psi-mi:q9u787_drome(display_long)|uniprotkb:Drep2(gene name)|psi-mi:Drep2(display_short)|uniprotkb:Drep-2(gene name synonym)|uniprotkb:Rep2(gene name synonym)|uniprotkb:drep2(gene name synonym)|uniprotkb:CG1975(orf name) psi-mi:q0e9b7_drome(display_long)|uniprotkb:Drep3(gene name)|psi-mi:Drep3(display_short)|uniprotkb:Drep-3(gene name synonym)|uniprotkb:Rep3(gene name synonym)|uniprotkb:"BcDNA:AT08574"(gene name synonym)|uniprotkb:CG13187(gene name synonym)|uniprotkb:DREP-3(gene name synonym)|uniprotkb:Dmel\CG8364(gene name synonym)|uniprotkb:drep-3(gene name synonym)|uniprotkb:drep3(gene name synonym)|uniprotkb:CG8364(orf name)|uniprotkb:Dmel_CG8364(orf name)|uniprotkb:DREP3(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2013) mint:MINT-8414264|mint:d-13-00073r1|pubmed:23485826 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504933|mint:MINT-8414331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028408|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|mint:Q9U787|mint:MINT-8414337(identity) refseq:NP_610722.2|refseq:NP_610723.2|flybase:FBgn0028407|ensemblmetazoa:FBgn0028407(gene)|ensemblmetazoa:FBtr0087979(transcript)|ensemblmetazoa:FBtr0087980(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|reactome:R-DME-8964572|mint:MINT-8414333(identity) - comment:mint - figure legend:f3|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/18 2014/10/16 rogid:xaXIToNPPDUaeY1dUv+ViY1spF47227 rogid:JYbrLt+5EpSanCJXbJ9oWS+rpcM7227 intact-crc:17FFB39E22C852CD|rigid:i7aWTPuvqDTAK1Qdxy+sFGeHfmM false mutation disrupting interaction:40-40(MINT-8414338)|binding-associated region:1-84(MINT-8414340) binding-associated region:111-195(MINT-8414334) - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9U787 uniprotkb:Q9U787 intact:EBI-8002851|intact:MINT-8387804 intact:EBI-8002851|intact:MINT-8387804 psi-mi:q9u787_drome(display_long)|uniprotkb:Drep2(gene name)|psi-mi:Drep2(display_short)|uniprotkb:Drep-2(gene name synonym)|uniprotkb:Rep2(gene name synonym)|uniprotkb:drep2(gene name synonym)|uniprotkb:CG1975(orf name) psi-mi:q9u787_drome(display_long)|uniprotkb:Drep2(gene name)|psi-mi:Drep2(display_short)|uniprotkb:Drep-2(gene name synonym)|uniprotkb:Rep2(gene name synonym)|uniprotkb:drep2(gene name synonym)|uniprotkb:CG1975(orf name) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2013) mint:MINT-8414264|mint:d-13-00073r1|pubmed:23485826 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504921|mint:MINT-8414308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028408|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|mint:Q9U787|mint:MINT-8414310(identity) flybase:FBgn0028408|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|mint:Q9U787|mint:MINT-8414310(identity) - comment:mint|comment:"Stoichiometry: 10.0" comment:mint|comment:"Stoichiometry: 10.0" figure legend:f2|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/18 2014/10/16 rogid:xaXIToNPPDUaeY1dUv+ViY1spF47227 rogid:xaXIToNPPDUaeY1dUv+ViY1spF47227 intact-crc:02FF05EE128802DA|rigid:4CGfXil86v52twjM2ikdzDT/WAU false binding-associated region:1-84(MINT-8414311) binding-associated region:1-84(MINT-8414311) 10 0 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9U787 uniprotkb:O61464 intact:EBI-8002851|intact:MINT-8387804 intact:EBI-870636 psi-mi:q9u787_drome(display_long)|uniprotkb:Drep2(gene name)|psi-mi:Drep2(display_short)|uniprotkb:Drep-2(gene name synonym)|uniprotkb:Rep2(gene name synonym)|uniprotkb:drep2(gene name synonym)|uniprotkb:CG1975(orf name) psi-mi:o61464_drome(display_long)|uniprotkb:Drep1(gene name)|psi-mi:Drep1(display_short)|uniprotkb:Drep-1(gene name synonym)|uniprotkb:Rep1(gene name synonym)|uniprotkb:drep1(gene name synonym)|uniprotkb:CG8357(orf name) psi-mi:"MI:0276"(blue native page) Lee et al. (2013) mint:MINT-8414264|mint:d-13-00073r1|pubmed:23485826 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504961|mint:MINT-8414348 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028408|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|mint:Q9U787|mint:MINT-8414354(identity) flybase:FBgn0024732|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045476"(nurse cell apoptotic process)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|mint:O61464|mint:MINT-8414350(identity) - comment:mint - figure legend:f4|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/18 2014/10/16 rogid:xaXIToNPPDUaeY1dUv+ViY1spF47227 rogid:blDkwfR4tiQTHQ5/vHJGMLpbjk87227 intact-crc:8B585279DC131895|rigid:qqeOQ6zBxqWPz7WYx55xIOTg/1s false mutation disrupting interaction:40-40(MINT-8414355)|binding-associated region:1-84(MINT-8414357) binding-associated region:1-90(MINT-8414351) - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9U787 uniprotkb:Q0E9B7 intact:EBI-8002851|intact:MINT-8387804 intact:EBI-97031|ensemblmetazoa:FBpp0087087|ensemblmetazoa:FBpp0087088 psi-mi:q9u787_drome(display_long)|uniprotkb:Drep2(gene name)|psi-mi:Drep2(display_short)|uniprotkb:Drep-2(gene name synonym)|uniprotkb:Rep2(gene name synonym)|uniprotkb:drep2(gene name synonym)|uniprotkb:CG1975(orf name) psi-mi:q0e9b7_drome(display_long)|uniprotkb:Drep3(gene name)|psi-mi:Drep3(display_short)|uniprotkb:Drep-3(gene name synonym)|uniprotkb:Rep3(gene name synonym)|uniprotkb:"BcDNA:AT08574"(gene name synonym)|uniprotkb:CG13187(gene name synonym)|uniprotkb:DREP-3(gene name synonym)|uniprotkb:Dmel\CG8364(gene name synonym)|uniprotkb:drep-3(gene name synonym)|uniprotkb:drep3(gene name synonym)|uniprotkb:CG8364(orf name)|uniprotkb:Dmel_CG8364(orf name)|uniprotkb:DREP3(gene name synonym) psi-mi:"MI:0276"(blue native page) Lee et al. (2013) mint:MINT-8414264|mint:d-13-00073r1|pubmed:23485826 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8504982|mint:MINT-8414364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0028408|go:"GO:0006915"(apoptotic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|mint:Q9U787|mint:MINT-8414370(identity) refseq:NP_610722.2|refseq:NP_610723.2|flybase:FBgn0028407|ensemblmetazoa:FBgn0028407(gene)|ensemblmetazoa:FBtr0087979(transcript)|ensemblmetazoa:FBtr0087980(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|reactome:R-DME-8964572|mint:MINT-8414366(identity) - comment:mint - figure legend:f4|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/02/18 2014/10/16 rogid:xaXIToNPPDUaeY1dUv+ViY1spF47227 rogid:JYbrLt+5EpSanCJXbJ9oWS+rpcM7227 intact-crc:73A861412AE41882|rigid:i7aWTPuvqDTAK1Qdxy+sFGeHfmM false binding-associated region:1-84(MINT-8414371)|mutation decreasing interaction:40-40(MINT-8414373) binding-associated region:111-195(MINT-8414367) - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining)