#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8C0J2 uniprotkb:Q9ESK9 intact:EBI-769195|uniprotkb:Q80U97|uniprotkb:Q80U98|uniprotkb:Q80U99|uniprotkb:Q80Y53|uniprotkb:Q9DB63|uniprotkb:Q6KAT7|ensembl:ENSMUSP00000027512 intact:EBI-647302|uniprotkb:E9QLQ2|uniprotkb:Q3TXX2|uniprotkb:Q61384|uniprotkb:Q8BRY9|uniprotkb:Q9JK14|ensembl:ENSMUSP00000027040 psi-mi:a16l1_mouse(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:Atg16l1(gene name)|psi-mi:Atg16l1(display_short)|uniprotkb:Apg16l(gene name synonym) psi-mi:rbcc1_mouse(display_long)|uniprotkb:Coiled-coil-forming protein 1(gene name synonym)|uniprotkb:LaXp180(gene name synonym)|uniprotkb:Rb1cc1(gene name)|psi-mi:Rb1cc1(display_short)|uniprotkb:Cc1(gene name synonym)|uniprotkb:Kiaa0203(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8390571|mint:MINT-8430587|imex:IM-20882-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001192320.1|refseq:NP_084122.2|dip:DIP-31966N|ensembl:ENSMUSG00000026289(gene)|ensembl:ENSMUST00000027512(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8C0J2|rcsb pdb:6SUR|rcsb pdb:6Y09|rcsb pdb:6ZAY|reactome:R-MMU-1632852|mint:MINT-8430589(identity) refseq:NP_033956.2|dip:DIP-49679N|ensembl:ENSMUSG00000025907(gene)|ensembl:ENSMUST00000027040(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q9ESK9|reactome:R-MMU-1632852|mint:MINT-8430590(identity) - - - figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/05/20 2014/10/16 rogid:gVwCDGIxRkSzS3z9wAWLdRDAZjo10090 rogid:DiOKxKS7K4NtKX4DqF9ZtpkcOcc10090 intact-crc:80F4772A249E5F55|rigid:sWoNSUyRHPqHfJchWSLPmXIlYxU false fusion protein:?-?(MINT-8430596) fusion protein:?-?(MINT-8430592) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TDY2 uniprotkb:Q676U5 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390597|mint:MINT-8430634|imex:IM-20882-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430640(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430642(identity) - - - figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:683E1B13F04966AC|rigid:d59uUG4EixNyIq9T34TuwjgEk2I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TDY2 uniprotkb:O75385 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390597|mint:MINT-8430634|imex:IM-20882-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430640(identity) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430638(identity) - - - figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 intact-crc:683E1B13F04966AC|rigid:d59uUG4EixNyIq9T34TuwjgEk2I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TDY2 uniprotkb:O75143 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390597|mint:MINT-8430634|imex:IM-20882-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430640(identity) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430636(identity) - - - figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 intact-crc:683E1B13F04966AC|rigid:d59uUG4EixNyIq9T34TuwjgEk2I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75143 uniprotkb:Q9BSB4 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 intact:EBI-2946739|ensembl:ENSP00000338990|uniprotkb:Q9HBN1|uniprotkb:Q9HAE2|intact:EBI-2949398 psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:atga1_human(display_long)|uniprotkb:ATG101(gene name)|psi-mi:ATG101(display_short)|uniprotkb:C12orf44(gene name synonym)|uniprotkb:PP894(orf name) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390684|mint:MINT-8430743|imex:IM-20882-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430751(identity) ensembl:ENSG00000123395(gene)|ensembl:ENST00000336854(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR012445(Protein of unknown function DUF1649)|rcsb pdb:4WZG|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|reactome:R-HSA-1632852|refseq:NP_001092143.1|refseq:NP_068753.2|dip:DIP-60653N|mint:MINT-8430753(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 rogid:j3WJNvGMNz8ArNPQUI20Iej5oAM9606 intact-crc:60CD72D82DBC169E|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75143 uniprotkb:Q9H1Y0 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 intact:EBI-1047414|uniprotkb:O60875|uniprotkb:Q5JVR2|uniprotkb:Q68DI4|uniprotkb:Q9H2B8|uniprotkb:Q9HCZ7|ensembl:ENSP00000343313|ensembl:ENSP00000358072 psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:atg5_human(display_long)|uniprotkb:APG5-like(gene name synonym)|uniprotkb:Apoptosis-specific protein(gene name synonym)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5L(gene name synonym)|uniprotkb:ASP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390684|mint:MINT-8430743|imex:IM-20882-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430751(identity) refseq:NP_001273035.1|refseq:NP_001273036.1|refseq:NP_001273037.1|refseq:NP_001273040.1|refseq:NP_004840.1|dip:DIP-29758N|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009620"(response to fungus)|go:"GO:0016020"(membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:4TQ1|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|ensembl:ENSG00000057663(gene)|ensembl:ENST00000343245(transcript)|ensembl:ENST00000369076(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)|mint:MINT-8431648(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 rogid:YqK4btJDQmY/dGxrmYxQmL+iAzc9606 intact-crc:60CD72D82DBC169E|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75143 uniprotkb:Q8TDY2 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390684|mint:MINT-8430743|imex:IM-20882-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430751(identity) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430747(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 intact-crc:60CD72D82DBC169E|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75143 uniprotkb:Q676U5 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390684|mint:MINT-8430743|imex:IM-20882-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430751(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430745(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:60CD72D82DBC169E|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75143 uniprotkb:O75385 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390684|mint:MINT-8430743|imex:IM-20882-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430751(identity) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430749(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 intact-crc:60CD72D82DBC169E|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TDY2 uniprotkb:Q676U5 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390636|mint:MINT-8430695|imex:IM-20882-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430699(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430697(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:AA135AF0061961AD|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TDY2 uniprotkb:O75385 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390636|mint:MINT-8430695|imex:IM-20882-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430699(identity) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430701(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 intact-crc:AA135AF0061961AD|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TDY2 uniprotkb:O75143 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390636|mint:MINT-8430695|imex:IM-20882-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430699(identity) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430703(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 intact-crc:AA135AF0061961AD|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TDY2 uniprotkb:Q9H1Y0 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 intact:EBI-1047414|uniprotkb:O60875|uniprotkb:Q5JVR2|uniprotkb:Q68DI4|uniprotkb:Q9H2B8|uniprotkb:Q9HCZ7|ensembl:ENSP00000343313|ensembl:ENSP00000358072 psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:atg5_human(display_long)|uniprotkb:APG5-like(gene name synonym)|uniprotkb:Apoptosis-specific protein(gene name synonym)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5L(gene name synonym)|uniprotkb:ASP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390636|mint:MINT-8430695|imex:IM-20882-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430699(identity) refseq:NP_001273035.1|refseq:NP_001273036.1|refseq:NP_001273037.1|refseq:NP_001273040.1|refseq:NP_004840.1|dip:DIP-29758N|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009620"(response to fungus)|go:"GO:0016020"(membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:4TQ1|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|ensembl:ENSG00000057663(gene)|ensembl:ENST00000343245(transcript)|ensembl:ENST00000369076(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)|mint:MINT-8431628(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rogid:YqK4btJDQmY/dGxrmYxQmL+iAzc9606 intact-crc:AA135AF0061961AD|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TDY2 uniprotkb:Q9BSB4 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 intact:EBI-2946739|ensembl:ENSP00000338990|uniprotkb:Q9HBN1|uniprotkb:Q9HAE2|intact:EBI-2949398 psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:atga1_human(display_long)|uniprotkb:ATG101(gene name)|psi-mi:ATG101(display_short)|uniprotkb:C12orf44(gene name synonym)|uniprotkb:PP894(orf name) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390636|mint:MINT-8430695|imex:IM-20882-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430699(identity) ensembl:ENSG00000123395(gene)|ensembl:ENST00000336854(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR012445(Protein of unknown function DUF1649)|rcsb pdb:4WZG|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|reactome:R-HSA-1632852|refseq:NP_001092143.1|refseq:NP_068753.2|dip:DIP-60653N|mint:MINT-8430720(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rogid:j3WJNvGMNz8ArNPQUI20Iej5oAM9606 intact-crc:AA135AF0061961AD|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75385 uniprotkb:Q8TDY2 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390660|mint:MINT-8430728|imex:IM-20882-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430734(identity) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430736(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 intact-crc:1AE7D5FB756EBB13|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75385 uniprotkb:Q676U5 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390660|mint:MINT-8430728|imex:IM-20882-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430734(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430738(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:1AE7D5FB756EBB13|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75385 uniprotkb:O75143 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390660|mint:MINT-8430728|imex:IM-20882-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430734(identity) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430732(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 intact-crc:1AE7D5FB756EBB13|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75385 uniprotkb:Q9BSB4 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 intact:EBI-2946739|ensembl:ENSP00000338990|uniprotkb:Q9HBN1|uniprotkb:Q9HAE2|intact:EBI-2949398 psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:atga1_human(display_long)|uniprotkb:ATG101(gene name)|psi-mi:ATG101(display_short)|uniprotkb:C12orf44(gene name synonym)|uniprotkb:PP894(orf name) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390660|mint:MINT-8430728|imex:IM-20882-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430734(identity) ensembl:ENSG00000123395(gene)|ensembl:ENST00000336854(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR012445(Protein of unknown function DUF1649)|rcsb pdb:4WZG|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|reactome:R-HSA-1632852|refseq:NP_001092143.1|refseq:NP_068753.2|dip:DIP-60653N|mint:MINT-8430730(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 rogid:j3WJNvGMNz8ArNPQUI20Iej5oAM9606 intact-crc:1AE7D5FB756EBB13|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O75385 uniprotkb:Q9H1Y0 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 intact:EBI-1047414|uniprotkb:O60875|uniprotkb:Q5JVR2|uniprotkb:Q68DI4|uniprotkb:Q9H2B8|uniprotkb:Q9HCZ7|ensembl:ENSP00000343313|ensembl:ENSP00000358072 psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:atg5_human(display_long)|uniprotkb:APG5-like(gene name synonym)|uniprotkb:Apoptosis-specific protein(gene name synonym)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5L(gene name synonym)|uniprotkb:ASP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390660|mint:MINT-8430728|imex:IM-20882-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430734(identity) refseq:NP_001273035.1|refseq:NP_001273036.1|refseq:NP_001273037.1|refseq:NP_001273040.1|refseq:NP_004840.1|dip:DIP-29758N|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009620"(response to fungus)|go:"GO:0016020"(membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:4TQ1|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|ensembl:ENSG00000057663(gene)|ensembl:ENST00000343245(transcript)|ensembl:ENST00000369076(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)|mint:MINT-8431645(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 rogid:YqK4btJDQmY/dGxrmYxQmL+iAzc9606 intact-crc:1AE7D5FB756EBB13|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q676U5 uniprotkb:Q8TDY2 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8390732|mint:MINT-8430779|imex:IM-20882-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430781(identity) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430783(identity) - - - comment:homomint|comment:mint|figure legend:f1f sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 intact-crc:3F14CF14233175B2|rigid:6U18Mbc4SpAEZ6BK5KaO4uR68x4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BSB4 uniprotkb:Q676U5 intact:EBI-2946739|ensembl:ENSP00000338990|uniprotkb:Q9HBN1|uniprotkb:Q9HAE2|intact:EBI-2949398 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:atga1_human(display_long)|uniprotkb:ATG101(gene name)|psi-mi:ATG101(display_short)|uniprotkb:C12orf44(gene name synonym)|uniprotkb:PP894(orf name) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390708|mint:MINT-8430758|imex:IM-20882-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123395(gene)|ensembl:ENST00000336854(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR012445(Protein of unknown function DUF1649)|rcsb pdb:4WZG|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|reactome:R-HSA-1632852|refseq:NP_001092143.1|refseq:NP_068753.2|dip:DIP-60653N|mint:MINT-8430760(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430768(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:j3WJNvGMNz8ArNPQUI20Iej5oAM9606 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:54C8354454D5680C|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BSB4 uniprotkb:Q9H1Y0 intact:EBI-2946739|ensembl:ENSP00000338990|uniprotkb:Q9HBN1|uniprotkb:Q9HAE2|intact:EBI-2949398 intact:EBI-1047414|uniprotkb:O60875|uniprotkb:Q5JVR2|uniprotkb:Q68DI4|uniprotkb:Q9H2B8|uniprotkb:Q9HCZ7|ensembl:ENSP00000343313|ensembl:ENSP00000358072 psi-mi:atga1_human(display_long)|uniprotkb:ATG101(gene name)|psi-mi:ATG101(display_short)|uniprotkb:C12orf44(gene name synonym)|uniprotkb:PP894(orf name) psi-mi:atg5_human(display_long)|uniprotkb:APG5-like(gene name synonym)|uniprotkb:Apoptosis-specific protein(gene name synonym)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5L(gene name synonym)|uniprotkb:ASP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390708|mint:MINT-8430758|imex:IM-20882-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123395(gene)|ensembl:ENST00000336854(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR012445(Protein of unknown function DUF1649)|rcsb pdb:4WZG|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|reactome:R-HSA-1632852|refseq:NP_001092143.1|refseq:NP_068753.2|dip:DIP-60653N|mint:MINT-8430760(identity) refseq:NP_001273035.1|refseq:NP_001273036.1|refseq:NP_001273037.1|refseq:NP_001273040.1|refseq:NP_004840.1|dip:DIP-29758N|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009620"(response to fungus)|go:"GO:0016020"(membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:4TQ1|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|ensembl:ENSG00000057663(gene)|ensembl:ENST00000343245(transcript)|ensembl:ENST00000369076(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)|mint:MINT-8431652(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:j3WJNvGMNz8ArNPQUI20Iej5oAM9606 rogid:YqK4btJDQmY/dGxrmYxQmL+iAzc9606 intact-crc:54C8354454D5680C|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BSB4 uniprotkb:Q8TDY2 intact:EBI-2946739|ensembl:ENSP00000338990|uniprotkb:Q9HBN1|uniprotkb:Q9HAE2|intact:EBI-2949398 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 psi-mi:atga1_human(display_long)|uniprotkb:ATG101(gene name)|psi-mi:ATG101(display_short)|uniprotkb:C12orf44(gene name synonym)|uniprotkb:PP894(orf name) psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390708|mint:MINT-8430758|imex:IM-20882-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123395(gene)|ensembl:ENST00000336854(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR012445(Protein of unknown function DUF1649)|rcsb pdb:4WZG|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|reactome:R-HSA-1632852|refseq:NP_001092143.1|refseq:NP_068753.2|dip:DIP-60653N|mint:MINT-8430760(identity) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8430766(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:j3WJNvGMNz8ArNPQUI20Iej5oAM9606 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 intact-crc:54C8354454D5680C|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BSB4 uniprotkb:O75385 intact:EBI-2946739|ensembl:ENSP00000338990|uniprotkb:Q9HBN1|uniprotkb:Q9HAE2|intact:EBI-2949398 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 psi-mi:atga1_human(display_long)|uniprotkb:ATG101(gene name)|psi-mi:ATG101(display_short)|uniprotkb:C12orf44(gene name synonym)|uniprotkb:PP894(orf name) psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390708|mint:MINT-8430758|imex:IM-20882-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123395(gene)|ensembl:ENST00000336854(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR012445(Protein of unknown function DUF1649)|rcsb pdb:4WZG|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|reactome:R-HSA-1632852|refseq:NP_001092143.1|refseq:NP_068753.2|dip:DIP-60653N|mint:MINT-8430760(identity) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430764(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:j3WJNvGMNz8ArNPQUI20Iej5oAM9606 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 intact-crc:54C8354454D5680C|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BSB4 uniprotkb:O75143 intact:EBI-2946739|ensembl:ENSP00000338990|uniprotkb:Q9HBN1|uniprotkb:Q9HAE2|intact:EBI-2949398 intact:EBI-2798775|ensembl:ENSP00000352500|ensembl:ENSP00000431974|uniprotkb:Q9BRL3|uniprotkb:Q9H8B0|uniprotkb:D3DQQ1|uniprotkb:D3DQQ2|uniprotkb:B4DFI4|uniprotkb:E9PQZ8|uniprotkb:Q53EN6|intact:EBI-28977728 psi-mi:atga1_human(display_long)|uniprotkb:ATG101(gene name)|psi-mi:ATG101(display_short)|uniprotkb:C12orf44(gene name synonym)|uniprotkb:PP894(orf name) psi-mi:atg13_human(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:KIAA0652(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390708|mint:MINT-8430758|imex:IM-20882-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123395(gene)|ensembl:ENST00000336854(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR012445(Protein of unknown function DUF1649)|rcsb pdb:4WZG|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|reactome:R-HSA-1632852|refseq:NP_001092143.1|refseq:NP_068753.2|dip:DIP-60653N|mint:MINT-8430760(identity) ensembl:ENSG00000175224(gene)|ensembl:ENST00000359513(transcript)|ensembl:ENST00000526508(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|mint:O75143|refseq:NP_001333240.1|refseq:NP_001333241.1|refseq:NP_001333242.1|refseq:NP_001333243.1|refseq:NP_001333244.1|refseq:NP_001333245.1|refseq:NP_001333248.1|refseq:NP_001333249.1|refseq:NP_001333250.1|ensembl:ENSP00000352500|ensembl:ENST00000524625|ensembl:ENSP00000433543|ensembl:ENSP00000431974|ensembl:ENST00000528494|ensembl:ENSP00000432412|ensembl:ENST00000529655|ensembl:ENSP00000433756|ensembl:ENST00000530500|ensembl:ENSP00000434390|ensembl:ENST00000683050|ensembl:ENSP00000507809|refseq:NP_001333251.1|refseq:XP_011518795.1|refseq:XP_011518798.1|refseq:XP_011518801.1|refseq:NP_001136145.1|refseq:NP_001192048.1|refseq:NP_001192049.1|refseq:NP_001192050.1|refseq:NP_001192051.1|refseq:NP_055556.2|refseq:NP_001333271.1|refseq:XP_016874088.1|refseq:XP_016874092.1|refseq:XP_016874096.1|refseq:NP_001333252.1|refseq:NP_001333253.1|refseq:NP_001333254.1|refseq:NP_001333255.1|refseq:NP_001333256.1|refseq:NP_001333257.1|refseq:NP_001333258.1|refseq:NP_001333259.1|refseq:NP_001333260.1|refseq:NP_001333261.1|refseq:XP_006718459.1|refseq:XP_005253322.1|refseq:XP_005253323.1|refseq:XP_005253325.1|refseq:NP_001333273.1|refseq:NP_001333275.1|refseq:NP_001333277.1|refseq:NP_001333278.1|refseq:NP_001333279.1|refseq:NP_001333280.1|refseq:NP_001333281.1|refseq:NP_001333282.1|refseq:NP_001333283.1|dip:DIP-60540N|rcsb pdb:3WAO|rcsb pdb:3WAP|rcsb pdb:5C50|rcsb pdb:5XUY|rcsb pdb:5XV1|rcsb pdb:5XV3|rcsb pdb:5XV4|rcsb pdb:5XV6|rcsb pdb:6HYN|reactome:R-HSA-1632852|rcsb pdb:3WAN|mint:MINT-8430762(identity) - - - figure legend:f1e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:j3WJNvGMNz8ArNPQUI20Iej5oAM9606 rogid:xlABwrglkoQu3OSb/8yLTQVxN8o9606 intact-crc:54C8354454D5680C|rigid:VVf1lQvpjnmFVJO/TfeONyrKiFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ESK9 uniprotkb:Q8C0J2 intact:EBI-647302|uniprotkb:E9QLQ2|uniprotkb:Q3TXX2|uniprotkb:Q61384|uniprotkb:Q8BRY9|uniprotkb:Q9JK14|ensembl:ENSMUSP00000027040 intact:EBI-769195|uniprotkb:Q80U97|uniprotkb:Q80U98|uniprotkb:Q80U99|uniprotkb:Q80Y53|uniprotkb:Q9DB63|uniprotkb:Q6KAT7|ensembl:ENSMUSP00000027512 psi-mi:rbcc1_mouse(display_long)|uniprotkb:Coiled-coil-forming protein 1(gene name synonym)|uniprotkb:LaXp180(gene name synonym)|uniprotkb:Rb1cc1(gene name)|psi-mi:Rb1cc1(display_short)|uniprotkb:Cc1(gene name synonym)|uniprotkb:Kiaa0203(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:a16l1_mouse(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:Atg16l1(gene name)|psi-mi:Atg16l1(display_short)|uniprotkb:Apg16l(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8390752|mint:MINT-8430794|imex:IM-20882-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033956.2|dip:DIP-49679N|ensembl:ENSMUSG00000025907(gene)|ensembl:ENSMUST00000027040(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q9ESK9|reactome:R-MMU-1632852|mint:MINT-8430796(identity) refseq:NP_001192320.1|refseq:NP_084122.2|dip:DIP-31966N|ensembl:ENSMUSG00000026289(gene)|ensembl:ENSMUST00000027512(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8C0J2|rcsb pdb:6SUR|rcsb pdb:6Y09|rcsb pdb:6ZAY|reactome:R-MMU-1632852|mint:MINT-8430800(identity) - - - figure legend:f1g|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:DiOKxKS7K4NtKX4DqF9ZtpkcOcc10090 rogid:gVwCDGIxRkSzS3z9wAWLdRDAZjo10090 intact-crc:E540381F624621CF|rigid:sWoNSUyRHPqHfJchWSLPmXIlYxU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ESK9 uniprotkb:O70405 intact:EBI-647302|uniprotkb:E9QLQ2|uniprotkb:Q3TXX2|uniprotkb:Q61384|uniprotkb:Q8BRY9|uniprotkb:Q9JK14|ensembl:ENSMUSP00000027040 intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2 psi-mi:rbcc1_mouse(display_long)|uniprotkb:Coiled-coil-forming protein 1(gene name synonym)|uniprotkb:LaXp180(gene name synonym)|uniprotkb:Rb1cc1(gene name)|psi-mi:Rb1cc1(display_short)|uniprotkb:Cc1(gene name synonym)|uniprotkb:Kiaa0203(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390765|mint:MINT-8431023|imex:IM-20882-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033956.2|dip:DIP-49679N|ensembl:ENSMUSG00000025907(gene)|ensembl:ENSMUST00000027040(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q9ESK9|reactome:R-MMU-1632852|mint:MINT-8431027(identity) refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:MINT-8431031(identity) - - comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells figure legend:sf2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:DiOKxKS7K4NtKX4DqF9ZtpkcOcc10090 rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090 intact-crc:5F428068242F75A4|rigid:AdJ5vpImgGtqYyhAz1k4OwpZKws false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ESK9 uniprotkb:Q8C0J2 intact:EBI-647302|uniprotkb:E9QLQ2|uniprotkb:Q3TXX2|uniprotkb:Q61384|uniprotkb:Q8BRY9|uniprotkb:Q9JK14|ensembl:ENSMUSP00000027040 intact:EBI-769195|uniprotkb:Q80U97|uniprotkb:Q80U98|uniprotkb:Q80U99|uniprotkb:Q80Y53|uniprotkb:Q9DB63|uniprotkb:Q6KAT7|ensembl:ENSMUSP00000027512 psi-mi:rbcc1_mouse(display_long)|uniprotkb:Coiled-coil-forming protein 1(gene name synonym)|uniprotkb:LaXp180(gene name synonym)|uniprotkb:Rb1cc1(gene name)|psi-mi:Rb1cc1(display_short)|uniprotkb:Cc1(gene name synonym)|uniprotkb:Kiaa0203(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:a16l1_mouse(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:Atg16l1(gene name)|psi-mi:Atg16l1(display_short)|uniprotkb:Apg16l(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390765|mint:MINT-8431023|imex:IM-20882-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033956.2|dip:DIP-49679N|ensembl:ENSMUSG00000025907(gene)|ensembl:ENSMUST00000027040(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q9ESK9|reactome:R-MMU-1632852|mint:MINT-8431027(identity) refseq:NP_001192320.1|refseq:NP_084122.2|dip:DIP-31966N|ensembl:ENSMUSG00000026289(gene)|ensembl:ENSMUST00000027512(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8C0J2|rcsb pdb:6SUR|rcsb pdb:6Y09|rcsb pdb:6ZAY|reactome:R-MMU-1632852|mint:MINT-8431025(identity) - - - figure legend:sf2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:DiOKxKS7K4NtKX4DqF9ZtpkcOcc10090 rogid:gVwCDGIxRkSzS3z9wAWLdRDAZjo10090 intact-crc:5F428068242F75A4|rigid:AdJ5vpImgGtqYyhAz1k4OwpZKws false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q676U5 uniprotkb:Q676U5 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8390849|mint:MINT-8430835|imex:IM-20882-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430837(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430838(identity) - - - figure legend:f3c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:275F1155D5A4EA7F|rigid:JUF828Ujn0aM76fm3nrbuzes9Gs false ha tag:?-?(MINT-8430839) binding-associated region:78-230(MINT-8430848)|flag tag:?-?(MINT-8430845) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q676U5 uniprotkb:Q9H1Y0 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 intact:EBI-1047414|uniprotkb:O60875|uniprotkb:Q5JVR2|uniprotkb:Q68DI4|uniprotkb:Q9H2B8|uniprotkb:Q9HCZ7|ensembl:ENSP00000343313|ensembl:ENSP00000358072 psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:atg5_human(display_long)|uniprotkb:APG5-like(gene name synonym)|uniprotkb:Apoptosis-specific protein(gene name synonym)|uniprotkb:ATG5(gene name)|psi-mi:ATG5(display_short)|uniprotkb:APG5L(gene name synonym)|uniprotkb:ASP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390871|mint:MINT-8431568|imex:IM-20882-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8431570(identity) refseq:NP_001273035.1|refseq:NP_001273036.1|refseq:NP_001273037.1|refseq:NP_001273040.1|refseq:NP_004840.1|dip:DIP-29758N|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0009620"(response to fungus)|go:"GO:0016020"(membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034274"(Atg12-Atg5-Atg16 complex)|go:"GO:0035973"(aggrephagy)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0048840"(otolith development)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060047"(heart contraction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|interpro:IPR007239(Autophagy protein 5)|interpro:IPR042526|interpro:IPR042527|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:4TQ1|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8934903|reactome:R-HSA-936440|ensembl:ENSG00000057663(gene)|ensembl:ENST00000343245(transcript)|ensembl:ENST00000369076(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002718"(regulation of cytokine production involved in immune response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006501"(C-terminal protein lipidation)|mint:MINT-8431576(identity) - - - comment:homomint|comment:mint|figure legend:sf4b f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 rogid:YqK4btJDQmY/dGxrmYxQmL+iAzc9606 intact-crc:B48E39DC05D55755|rigid:yQ+lTsc5kot5/PgRkYjTzA5n9WE false flag tag:?-?(MINT-8431587) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q676U5 uniprotkb:Q8TDY2 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8390871|mint:MINT-8431568|imex:IM-20882-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8431570(identity) refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N|mint:MINT-8431572(identity) - - - comment:homomint|comment:mint|figure legend:sf4b f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/05/20 2014/10/16 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 intact-crc:B48E39DC05D55755|rigid:yQ+lTsc5kot5/PgRkYjTzA5n9WE false flag tag:?-?(MINT-8431587) ha tag:?-?(MINT-8431591) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q64337 uniprotkb:Q676U5 intact:EBI-645025|uniprotkb:Q99JM8|ensembl:ENSMUSP00000099835 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:sqstm_mouse(display_long)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:STONE14(gene name synonym)|uniprotkb:Sqstm1(gene name)|psi-mi:Sqstm1(display_short)|uniprotkb:A170(gene name synonym)|uniprotkb:STAP(gene name synonym) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8390920|mint:MINT-8430937|imex:IM-20882-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001277698.1|refseq:NP_035148.1|ensembl:ENSMUSG00000015837(gene)|ensembl:ENSMUST00000102774(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR033741|interpro:IPR034866|interpro:IPR043145|mint:Q64337|rcsb pdb:2RRU|rcsb pdb:2ZJD|rcsb pdb:3ADE|rcsb pdb:3B0F|rcsb pdb:3WDZ|reactome:R-MMU-205043|reactome:R-MMU-209543|reactome:R-MMU-209560|reactome:R-MMU-5205685|reactome:R-MMU-9020702|reactome:R-MMU-9664873|dip:DIP-38490N|mint:MINT-8430943(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430947(identity) go:"GO:0000421"(autophagosome membrane) - - figure legend:f5d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:/BktZPkmiLsU1fKVqPSQ8ae2+SY10090 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:4AEC81902231AF52|rigid:QMbSrBFehE40aF6YB2jTbKJ76pc false - cyan fluorescent protein tag:?-?(MINT-8430998)|binding-associated region:1-230(MINT-8431000) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q676U5 uniprotkb:Q9CQV6 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 intact:EBI-7942066|uniprotkb:Q3U9W5|intact:UNK-5540201|uniprotkb:Q9D1R0|ensembl:ENSMUSP00000034270 psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:mlp3b_mouse(display_long)|uniprotkb:Map1lc3b(gene name)|psi-mi:Map1lc3b(display_short)|uniprotkb:Map1alc3(gene name synonym)|uniprotkb:Map1lc3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8390901|mint:MINT-8430856|imex:IM-20882-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430858(identity) refseq:NP_080436.1|dip:DIP-61580N|go:"GO:0012505"(endomembrane system)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044754"(autolysosome)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:5WRD|rcsb pdb:5YIQ|rcsb pdb:5YIS|reactome:R-MMU-1632852|reactome:R-MMU-5205685|reactome:R-MMU-8854214|reactome:R-MMU-8934903|reactome:R-MMU-9664873|go:"GO:0009267"(cellular response to starvation)|ensembl:ENSMUSG00000031812(gene)|ensembl:ENSMUST00000034270(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|mint:MINT-8430914(identity) go:"GO:0005768"(endosome) - comment:mint|function:"Probably involved in formation of autophagosomal vacuoles (autophagosomes)" figure legend:f4b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 rogid:i7XYb/AU0h/HmGBNN0hFhJJ/GEw10090 intact-crc:EC3E3C4572790728|rigid:+SEbUG5mAVJc4L+oKPJI//raN3Q false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q676U5 uniprotkb:O75385 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8390901|mint:MINT-8430856|imex:IM-20882-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8430858(identity) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8430862(identity) go:"GO:0005768"(endosome) - - figure legend:f4b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 intact-crc:EC3E3C4572790728|rigid:+SEbUG5mAVJc4L+oKPJI//raN3Q false - green fluorescent protein tag:?-?(MINT-8430907) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O75385 uniprotkb:Q676U5 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8390980|mint:MINT-8431602|imex:IM-20882-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8431608(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8431612(identity) go:"GO:0005768"(endosome) - - comment:homomint|comment:mint|figure legend:sf6 sf7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:1804B9A4D8D95325|rigid:89L4318LTsSlcx/9YaVOimjRqhY false green fluorescent protein tag:?-?(MINT-8431609) flag tag:?-?(MINT-8431618) - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q68FE2 uniprotkb:Q676U5 intact:EBI-7091482|ensembl:ENSMUSP00000159170|intact:UNK-5419756|intact:EBI-8390940|intact:UNK-5468806|uniprotkb:Q3ZAQ4 intact:EBI-535909|uniprotkb:Q6IPN1|uniprotkb:Q6UXW4|uniprotkb:Q6ZVZ5|uniprotkb:Q8NCY2|uniprotkb:Q96JV5|uniprotkb:Q9H619|uniprotkb:A3EXK9|uniprotkb:A3EXL0|uniprotkb:B6ZDH0|ensembl:ENSP00000375872|ensembl:ENSP00000487542 psi-mi:atg9a_mouse(display_long)|uniprotkb:Atg9a(gene name)|psi-mi:Atg9a(display_short)|uniprotkb:Apg9l1(gene name synonym)|uniprotkb:APG9-like 1(gene name synonym) psi-mi:a16l1_human(display_long)|uniprotkb:APG16-like 1(gene name synonym)|uniprotkb:UNQ9393/PRO34307(orf name)|uniprotkb:ATG16L1(gene name)|psi-mi:ATG16L1(display_short)|uniprotkb:APG16L(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8390961|mint:MINT-8431007|imex:IM-20882-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001275541.1|ensembl:ENSMUSG00000033124(gene)|ensembl:ENSMUST00000239085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|reactome:R-MMU-1632852|mint:Q68FE2|refseq:NP_001003917.2|mint:MINT-8431010(identity) refseq:NP_001177195.1|refseq:NP_001177196.1|refseq:NP_060444.3|refseq:NP_110430.5|refseq:NP_942593.2|dip:DIP-27552N|dip:DIP-50290N|ensembl:ENSG00000085978(gene)|ensembl:ENSG00000281089(gene)|ensembl:ENST00000392017(transcript)|ensembl:ENST00000625501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0061739"(protein lipidation involved in autophagosome assembly)|go:"GO:0098792"(xenophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|interpro:IPR001680(WD40 repeat)|interpro:IPR013923(Autophagy protein 16)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q676U5|rcsb pdb:4GDK|rcsb pdb:4GDL|rcsb pdb:4NAW|rcsb pdb:4TQ0|rcsb pdb:5D7G|rcsb pdb:5NPV|rcsb pdb:5NPW|rcsb pdb:5NUV|rcsb pdb:5ZYX|reactome:R-HSA-1632852|mint:MINT-8431012(identity) go:"GO:0000421"(autophagosome membrane) comment:mint - figure legend:f5c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2021/12/01 rogid:JXXrkgG3yJQKPuDs4y5dzrYh2w010090 rogid:rLwpmIwMwd/GgPJA+7OKYTnn73E9606 intact-crc:529B8D9328FD5998|rigid:WLTL0VwzuDLuj7WdYm5sUL9eYj0 false - cyan fluorescent protein tag:?-?(MINT-8431015)|binding-associated region:1-230(MINT-8431013) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q91YI1 uniprotkb:Q9ESK9 intact:EBI-8391007|uniprotkb:A2AH18|uniprotkb:Q80TU9|intact:MINT-8431155|ensembl:ENSMUSP00000028678 intact:EBI-647302|uniprotkb:E9QLQ2|uniprotkb:Q3TXX2|uniprotkb:Q61384|uniprotkb:Q8BRY9|uniprotkb:Q9JK14|ensembl:ENSMUSP00000027040 psi-mi:atg13_mouse(display_long)|uniprotkb:Atg13(gene name)|psi-mi:Atg13(display_short)|uniprotkb:D2Ertd391e(gene name synonym)|uniprotkb:Kiaa0652(gene name synonym) psi-mi:rbcc1_mouse(display_long)|uniprotkb:Coiled-coil-forming protein 1(gene name synonym)|uniprotkb:LaXp180(gene name synonym)|uniprotkb:Rb1cc1(gene name)|psi-mi:Rb1cc1(display_short)|uniprotkb:Cc1(gene name synonym)|uniprotkb:Kiaa0203(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8391027|mint:MINT-8431174|imex:IM-20882-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_663503.1|refseq:XP_006499953.1|dip:DIP-60542N|ensembl:ENSMUSG00000027244(gene)|ensembl:ENSMUST00000028678(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|reactome:R-MMU-1632852|mint:MINT-8431176(identity) refseq:NP_033956.2|dip:DIP-49679N|ensembl:ENSMUSG00000025907(gene)|ensembl:ENSMUST00000027040(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q9ESK9|reactome:R-MMU-1632852|mint:MINT-8431189(identity) - comment:mint|comment:homomint - figure legend:sf3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2014/10/16 rogid:S3Y59Y3/qczjHpiwUtWlEdmzkvA10090 rogid:DiOKxKS7K4NtKX4DqF9ZtpkcOcc10090 intact-crc:FCD8E5DC0FAB445A|rigid:N8KJbIX0NVyAWlB9KhPOrzkCGxY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q91YI1 uniprotkb:O70405 intact:EBI-8391007|uniprotkb:A2AH18|uniprotkb:Q80TU9|intact:MINT-8431155|ensembl:ENSMUSP00000028678 intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2 psi-mi:atg13_mouse(display_long)|uniprotkb:Atg13(gene name)|psi-mi:Atg13(display_short)|uniprotkb:D2Ertd391e(gene name synonym)|uniprotkb:Kiaa0652(gene name synonym) psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8391027|mint:MINT-8431174|imex:IM-20882-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_663503.1|refseq:XP_006499953.1|dip:DIP-60542N|ensembl:ENSMUSG00000027244(gene)|ensembl:ENSMUST00000028678(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|reactome:R-MMU-1632852|mint:MINT-8431176(identity) refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:MINT-8431180(identity) - comment:mint|comment:homomint comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells figure legend:sf3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/05/20 2014/10/16 rogid:S3Y59Y3/qczjHpiwUtWlEdmzkvA10090 rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090 intact-crc:FCD8E5DC0FAB445A|rigid:N8KJbIX0NVyAWlB9KhPOrzkCGxY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ESK9 uniprotkb:O70405 intact:EBI-647302|uniprotkb:E9QLQ2|uniprotkb:Q3TXX2|uniprotkb:Q61384|uniprotkb:Q8BRY9|uniprotkb:Q9JK14|ensembl:ENSMUSP00000027040 intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2 psi-mi:rbcc1_mouse(display_long)|uniprotkb:Coiled-coil-forming protein 1(gene name synonym)|uniprotkb:LaXp180(gene name synonym)|uniprotkb:Rb1cc1(gene name)|psi-mi:Rb1cc1(display_short)|uniprotkb:Cc1(gene name synonym)|uniprotkb:Kiaa0203(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8391050|mint:MINT-8431441|imex:IM-20882-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033956.2|dip:DIP-49679N|ensembl:ENSMUSG00000025907(gene)|ensembl:ENSMUST00000027040(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q9ESK9|reactome:R-MMU-1632852|mint:MINT-8431443(identity) refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:MINT-8431445(identity) - - comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells figure legend:sf3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:DiOKxKS7K4NtKX4DqF9ZtpkcOcc10090 rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090 intact-crc:3464FE5F5DF5264F|rigid:N8KJbIX0NVyAWlB9KhPOrzkCGxY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ESK9 uniprotkb:Q91YI1 intact:EBI-647302|uniprotkb:E9QLQ2|uniprotkb:Q3TXX2|uniprotkb:Q61384|uniprotkb:Q8BRY9|uniprotkb:Q9JK14|ensembl:ENSMUSP00000027040 intact:EBI-8391007|uniprotkb:A2AH18|uniprotkb:Q80TU9|intact:MINT-8431155|ensembl:ENSMUSP00000028678 psi-mi:rbcc1_mouse(display_long)|uniprotkb:Coiled-coil-forming protein 1(gene name synonym)|uniprotkb:LaXp180(gene name synonym)|uniprotkb:Rb1cc1(gene name)|psi-mi:Rb1cc1(display_short)|uniprotkb:Cc1(gene name synonym)|uniprotkb:Kiaa0203(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:atg13_mouse(display_long)|uniprotkb:Atg13(gene name)|psi-mi:Atg13(display_short)|uniprotkb:D2Ertd391e(gene name synonym)|uniprotkb:Kiaa0652(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nishimura et al. (2013) pubmed:23392225|imex:IM-20882|mint:MINT-8428476 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8391050|mint:MINT-8431441|imex:IM-20882-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033956.2|dip:DIP-49679N|ensembl:ENSMUSG00000025907(gene)|ensembl:ENSMUST00000027040(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q9ESK9|reactome:R-MMU-1632852|mint:MINT-8431443(identity) refseq:NP_663503.1|refseq:XP_006499953.1|dip:DIP-60542N|ensembl:ENSMUSG00000027244(gene)|ensembl:ENSMUST00000028678(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|reactome:R-MMU-1632852|mint:MINT-8431447(identity) - - comment:mint|comment:homomint figure legend:sf3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2013/05/20 2014/10/16 rogid:DiOKxKS7K4NtKX4DqF9ZtpkcOcc10090 rogid:S3Y59Y3/qczjHpiwUtWlEdmzkvA10090 intact-crc:3464FE5F5DF5264F|rigid:N8KJbIX0NVyAWlB9KhPOrzkCGxY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)