#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q60809 uniprotkb:Q9ULM6 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-2104530|uniprotkb:D3DWR0|uniprotkb:A7MD46|ensembl:ENSP00000261951|ensembl:ENSP00000377024|ensembl:ENSP00000481893 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot6_human(display_long)|uniprotkb:CNOT6(gene name)|psi-mi:CNOT6(display_short)|uniprotkb:CCR4(gene name synonym)|uniprotkb:KIAA1194(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog(gene name synonym)|uniprotkb:CCR4 carbon catabolite repression 4-like(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:CCR4a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:XP_011532908.1|refseq:XP_011532909.1|refseq:NP_001290170.1|refseq:XP_005266010.1|dip:DIP-46838N|ensembl:ENSG00000113300(gene)|ensembl:ENST00000261951(transcript)|ensembl:ENST00000393356(transcript)|ensembl:ENST00000618123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034966|interpro:IPR036691|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-5617472|reactome:R-HSA-6804115 - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:zxSIU+XaCoDUIUyPz5YpQycyaj49606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:Q9UIV1 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-2105113|uniprotkb:A8MZM5|uniprotkb:Q7Z530|uniprotkb:D3DSP6|uniprotkb:B3KMP1|uniprotkb:B3KN35|uniprotkb:G3V108|ensembl:ENSP00000355279 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot7_human(display_long)|uniprotkb:CNOT7(gene name)|psi-mi:CNOT7(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:BTG1-binding factor 1(gene name synonym)|uniprotkb:Caf1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_001309026.1|refseq:NP_001309028.1|refseq:NP_001309029.1|refseq:NP_001309016.1|refseq:NP_001309017.1|refseq:NP_001309018.1|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_037486.2|refseq:NP_473367.2|refseq:XP_005273538.1|refseq:NP_001309027.1|dip:DIP-41902N|ensembl:ENSG00000198791(gene)|ensembl:ENST00000361272(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q9UIV1|rcsb pdb:2D5R|rcsb pdb:4GMJ|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:+bu5LFmE8SFVSqNkFf91SSN3kVI9606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:A5YKK6 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:Q92600 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-357079|uniprotkb:Q96IX4|uniprotkb:B2RPI0|uniprotkb:B7Z1E5|uniprotkb:B5MDQ4|ensembl:ENSP00000273064|ensembl:ENSP00000443687 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot9_human(display_long)|uniprotkb:Cell differentiation protein RQCD1 homolog(gene name synonym)|uniprotkb:RCD1(gene name synonym)|uniprotkb:RQCD1(gene name synonym)|uniprotkb:CNOT9(gene name)|psi-mi:CNOT9(display_short) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 dip:DIP-46840N|refseq:NP_005435.1|refseq:NP_001258564.1|refseq:NP_001258563.1|ensembl:ENSG00000144580(gene)|ensembl:ENST00000273064(transcript)|ensembl:ENST00000542068(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:2FV2|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:5LSW|rcsb pdb:5ONA|rcsb pdb:5ONB|rcsb pdb:6HOM|rcsb pdb:6HON|reactome:R-HSA-429947|reactome:R-HSA-5617472|reactome:R-HSA-6804115 - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:/oDjYD0axKIkLMKxmji2q+sg+K49606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:Q9NZN8 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-743033|uniprotkb:Q9H3E0|uniprotkb:Q9NSX5|uniprotkb:Q9NWR6|uniprotkb:Q9P028|ensembl:ENSP00000229195|ensembl:ENSP00000412091|ensembl:ENSP00000449260 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot2_human(display_long)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:CNOT2(gene name)|psi-mi:CNOT2(display_short)|uniprotkb:CDC36(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:HSPC131(orf name)|uniprotkb:MSTP046(orf name) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_001186231.1|refseq:NP_001186232.1|refseq:XP_011536701.1|refseq:NP_055330.1|dip:DIP-42656N|reactome:R-HSA-429947|reactome:R-HSA-6804115|rcsb pdb:5FU7|ensembl:ENSG00000111596(gene)|ensembl:ENST00000229195(transcript)|ensembl:ENST00000418359(transcript)|ensembl:ENST00000551043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001222"(transcription corepressor binding)|rcsb pdb:5FU6|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|mint:Q9NZN8|rcsb pdb:4C0D|rcsb pdb:4C0F - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:EuftUgW57O3LzzkQmgktP/V+eQk9606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:Q9UKZ1 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:Q96LI5 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-1046635|ensembl:ENSP00000424896|intact:EBI-2562020|uniprotkb:Q9UF92 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cno6l_human(display_long)|uniprotkb:CCR4B(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog B(gene name synonym)|uniprotkb:CNOT6L(gene name)|psi-mi:CNOT6L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_653172.2|ensembl:ENSG00000138767(gene)|ensembl:ENST00000504123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034967|interpro:IPR036691|rcsb pdb:3NGN|rcsb pdb:3NGO|rcsb pdb:3NGQ|rcsb pdb:5DV2|rcsb pdb:5DV4|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_001273719.1|dip:DIP-46837N - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:2Y605zw41TOo2ATkUM/7ToUb6449606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:P52907 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231 - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:O75175 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:Q9H9A5 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-1054261|uniprotkb:Q9BU30|uniprotkb:Q9H5J7|uniprotkb:Q9H8X1|uniprotkb:Q9H9W0|uniprotkb:Q9HAH3|uniprotkb:Q9UFJ2|uniprotkb:B7Z7L1|uniprotkb:F8WAF2|intact:EBI-2562025|ensembl:ENSP00000330060 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cno10_human(display_long)|uniprotkb:CNOT10(gene name)|psi-mi:CNOT10(display_short) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502960 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_001243670.1|refseq:NP_056257.1|refseq:NP_001243671.1|ensembl:ENSG00000182973(gene)|ensembl:ENST00000328834(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039740|mint:Q9H9A5|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-46839N - - - figure legend:1, supplemt. table I|comment:Beta-tubulin was also found associated but cannot be mapped to UniProt AcNo. Association of CAPZA1 is probably unspecific.|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:92BjBXGyxALldfF9AVpP+EFN38k9606 intact-crc:967652D7D0B8BA4A|rigid:EWCMlaWiYg+vmTI2cotEjdgR5s8 false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UKZ1 uniprotkb:A5YKK6 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949 psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502998 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:3B|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606 intact-crc:6F16D80556430640|rigid:0TGlunwEhofQ1WqK/Hb9oX57Viw false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UKZ1 uniprotkb:Q9H9A5 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 intact:EBI-1054261|uniprotkb:Q9BU30|uniprotkb:Q9H5J7|uniprotkb:Q9H8X1|uniprotkb:Q9H9W0|uniprotkb:Q9HAH3|uniprotkb:Q9UFJ2|uniprotkb:B7Z7L1|uniprotkb:F8WAF2|intact:EBI-2562025|ensembl:ENSP00000330060 psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:cno10_human(display_long)|uniprotkb:CNOT10(gene name)|psi-mi:CNOT10(display_short) psi-mi:"MI:0676"(tandem affinity purification) Mauxion et al. (2012) pubmed:23232451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502998 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 refseq:NP_001243670.1|refseq:NP_056257.1|refseq:NP_001243671.1|ensembl:ENSG00000182973(gene)|ensembl:ENST00000328834(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039740|mint:Q9H9A5|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-46839N - - - figure legend:3B|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 rogid:92BjBXGyxALldfF9AVpP+EFN38k9606 intact-crc:6F16D80556430640|rigid:0TGlunwEhofQ1WqK/Hb9oX57Viw false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60809 uniprotkb:Q9UKZ1 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:"MI:0096"(pull down) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6502994 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:3A and supplemt. 1A|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 intact-crc:650A75BA8A4EB7BE|rigid:PFzQ0Iv/UE9VCqmGeRpVRZnZzUg false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q60809 uniprotkb:Q9ULM6 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-2104530|uniprotkb:D3DWR0|uniprotkb:A7MD46|ensembl:ENSP00000261951|ensembl:ENSP00000377024|ensembl:ENSP00000481893 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot6_human(display_long)|uniprotkb:CNOT6(gene name)|psi-mi:CNOT6(display_short)|uniprotkb:CCR4(gene name synonym)|uniprotkb:KIAA1194(gene name synonym)|uniprotkb:Carbon catabolite repressor protein 4 homolog(gene name synonym)|uniprotkb:CCR4 carbon catabolite repression 4-like(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:CCR4a(gene name synonym) psi-mi:"MI:0096"(pull down) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503017 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:XP_011532908.1|refseq:XP_011532909.1|refseq:NP_001290170.1|refseq:XP_005266010.1|dip:DIP-46838N|ensembl:ENSG00000113300(gene)|ensembl:ENST00000261951(transcript)|ensembl:ENST00000393356(transcript)|ensembl:ENST00000618123(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR032675|interpro:IPR034966|interpro:IPR036691|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-5617472|reactome:R-HSA-6804115 - - - figure legend:4|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:zxSIU+XaCoDUIUyPz5YpQycyaj49606 intact-crc:EADFFF6A0E936A49|rigid:Un4SpYwbNGRYUAPPPKbcW0iqgqs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60809 uniprotkb:Q9NZN8 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-743033|uniprotkb:Q9H3E0|uniprotkb:Q9NSX5|uniprotkb:Q9NWR6|uniprotkb:Q9P028|ensembl:ENSP00000229195|ensembl:ENSP00000412091|ensembl:ENSP00000449260 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot2_human(display_long)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:CNOT2(gene name)|psi-mi:CNOT2(display_short)|uniprotkb:CDC36(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:HSPC131(orf name)|uniprotkb:MSTP046(orf name) psi-mi:"MI:0096"(pull down) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503017 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_001186231.1|refseq:NP_001186232.1|refseq:XP_011536701.1|refseq:NP_055330.1|dip:DIP-42656N|reactome:R-HSA-429947|reactome:R-HSA-6804115|rcsb pdb:5FU7|ensembl:ENSG00000111596(gene)|ensembl:ENST00000229195(transcript)|ensembl:ENST00000418359(transcript)|ensembl:ENST00000551043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001222"(transcription corepressor binding)|rcsb pdb:5FU6|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|mint:Q9NZN8|rcsb pdb:4C0D|rcsb pdb:4C0F - - - figure legend:4|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:EuftUgW57O3LzzkQmgktP/V+eQk9606 intact-crc:EADFFF6A0E936A49|rigid:Un4SpYwbNGRYUAPPPKbcW0iqgqs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60809 uniprotkb:Q92600 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-357079|uniprotkb:Q96IX4|uniprotkb:B2RPI0|uniprotkb:B7Z1E5|uniprotkb:B5MDQ4|ensembl:ENSP00000273064|ensembl:ENSP00000443687 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot9_human(display_long)|uniprotkb:Cell differentiation protein RQCD1 homolog(gene name synonym)|uniprotkb:RCD1(gene name synonym)|uniprotkb:RQCD1(gene name synonym)|uniprotkb:CNOT9(gene name)|psi-mi:CNOT9(display_short) psi-mi:"MI:0096"(pull down) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503017 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 dip:DIP-46840N|refseq:NP_005435.1|refseq:NP_001258564.1|refseq:NP_001258563.1|ensembl:ENSG00000144580(gene)|ensembl:ENST00000273064(transcript)|ensembl:ENST00000542068(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:2FV2|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:5LSW|rcsb pdb:5ONA|rcsb pdb:5ONB|rcsb pdb:6HOM|rcsb pdb:6HON|reactome:R-HSA-429947|reactome:R-HSA-5617472|reactome:R-HSA-6804115 - - - figure legend:4|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:/oDjYD0axKIkLMKxmji2q+sg+K49606 intact-crc:EADFFF6A0E936A49|rigid:Un4SpYwbNGRYUAPPPKbcW0iqgqs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60809 uniprotkb:Q9H9A5 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-1054261|uniprotkb:Q9BU30|uniprotkb:Q9H5J7|uniprotkb:Q9H8X1|uniprotkb:Q9H9W0|uniprotkb:Q9HAH3|uniprotkb:Q9UFJ2|uniprotkb:B7Z7L1|uniprotkb:F8WAF2|intact:EBI-2562025|ensembl:ENSP00000330060 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cno10_human(display_long)|uniprotkb:CNOT10(gene name)|psi-mi:CNOT10(display_short) psi-mi:"MI:0096"(pull down) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503017 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_001243670.1|refseq:NP_056257.1|refseq:NP_001243671.1|ensembl:ENSG00000182973(gene)|ensembl:ENST00000328834(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039740|mint:Q9H9A5|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-46839N - - - figure legend:4|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:92BjBXGyxALldfF9AVpP+EFN38k9606 intact-crc:EADFFF6A0E936A49|rigid:Un4SpYwbNGRYUAPPPKbcW0iqgqs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60809 uniprotkb:Q9UKZ1 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:"MI:0096"(pull down) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503017 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:4|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 intact-crc:EADFFF6A0E936A49|rigid:Un4SpYwbNGRYUAPPPKbcW0iqgqs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60809 uniprotkb:O75175 intact:EBI-2104739|ensembl:ENSMUSP00000034012|ensembl:ENSMUSP00000117304|ensembl:ENSMUSP00000122933 intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867 psi-mi:cnot7_mouse(display_long)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:Cnot7(gene name)|psi-mi:Cnot7(display_short)|uniprotkb:Caf1(gene name synonym) psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym) psi-mi:"MI:0096"(pull down) Mauxion et al. (2012) pubmed:23232451 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503017 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011240485.1|refseq:NP_001258471.1|refseq:NP_035265.1|dip:DIP-46843N|ensembl:ENSMUSG00000031601(gene)|ensembl:ENSMUST00000034012(transcript)|ensembl:ENSMUST00000132032(transcript)|ensembl:ENSMUST00000149992(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q60809|reactome:R-MMU-429947|reactome:R-MMU-6804115 ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N - - - figure legend:4|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:99jca+XuNmn13TTgOG/bfAEbt4E10090 rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606 intact-crc:EADFFF6A0E936A49|rigid:Un4SpYwbNGRYUAPPPKbcW0iqgqs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UKZ1 uniprotkb:Q9H9A5 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 intact:EBI-1054261|uniprotkb:Q9BU30|uniprotkb:Q9H5J7|uniprotkb:Q9H8X1|uniprotkb:Q9H9W0|uniprotkb:Q9HAH3|uniprotkb:Q9UFJ2|uniprotkb:B7Z7L1|uniprotkb:F8WAF2|intact:EBI-2562025|ensembl:ENSP00000330060 psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:cno10_human(display_long)|uniprotkb:CNOT10(gene name)|psi-mi:CNOT10(display_short) psi-mi:"MI:0096"(pull down) Mauxion et al. (2012) pubmed:23232451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503055 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 refseq:NP_001243670.1|refseq:NP_056257.1|refseq:NP_001243671.1|ensembl:ENSG00000182973(gene)|ensembl:ENST00000328834(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039740|mint:Q9H9A5|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-46839N - - - figure legend:supplement. 1B|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/24 2014/10/16 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 rogid:92BjBXGyxALldfF9AVpP+EFN38k9606 intact-crc:E584A9637F16C2F0|rigid:ie3MPAhRrd4yEUGEj5ugNoMlV0U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UKZ1 uniprotkb:Q9UKZ1 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:"MI:0018"(two hybrid) Mauxion et al. (2012) pubmed:23232451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503035 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:5|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/01/24 2014/10/16 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 intact-crc:71CF011410373E8A|rigid:vC1LlX5+pIO6FsPqwcSHI5O73Vk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UKZ1 uniprotkb:Q9H9A5 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 intact:EBI-1054261|uniprotkb:Q9BU30|uniprotkb:Q9H5J7|uniprotkb:Q9H8X1|uniprotkb:Q9H9W0|uniprotkb:Q9HAH3|uniprotkb:Q9UFJ2|uniprotkb:B7Z7L1|uniprotkb:F8WAF2|intact:EBI-2562025|ensembl:ENSP00000330060 psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:cno10_human(display_long)|uniprotkb:CNOT10(gene name)|psi-mi:CNOT10(display_short) psi-mi:"MI:0018"(two hybrid) Mauxion et al. (2012) pubmed:23232451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503039 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 refseq:NP_001243670.1|refseq:NP_056257.1|refseq:NP_001243671.1|ensembl:ENSG00000182973(gene)|ensembl:ENST00000328834(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039740|mint:Q9H9A5|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-46839N - - - figure legend:5|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/01/24 2014/10/16 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 rogid:92BjBXGyxALldfF9AVpP+EFN38k9606 intact-crc:EABCD90FF5ACCDB7|rigid:ie3MPAhRrd4yEUGEj5ugNoMlV0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5YKK6 uniprotkb:Q9UKZ1 intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name) psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:"MI:0018"(two hybrid) Mauxion et al. (2012) pubmed:23232451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503043 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115 refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:5|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/01/24 2014/10/16 rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 intact-crc:924654C8C9730CE6|rigid:c/Tc2CZ8+CG0sqpSjHv6nXMlVS0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9A5 uniprotkb:Q9UKZ1 intact:EBI-1054261|uniprotkb:Q9BU30|uniprotkb:Q9H5J7|uniprotkb:Q9H8X1|uniprotkb:Q9H9W0|uniprotkb:Q9HAH3|uniprotkb:Q9UFJ2|uniprotkb:B7Z7L1|uniprotkb:F8WAF2|intact:EBI-2562025|ensembl:ENSP00000330060 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 psi-mi:cno10_human(display_long)|uniprotkb:CNOT10(gene name)|psi-mi:CNOT10(display_short) psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:"MI:0018"(two hybrid) Mauxion et al. (2012) pubmed:23232451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503047 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243670.1|refseq:NP_056257.1|refseq:NP_001243671.1|ensembl:ENSG00000182973(gene)|ensembl:ENST00000328834(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039740|mint:Q9H9A5|reactome:R-HSA-429947|reactome:R-HSA-6804115|dip:DIP-46839N refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:5|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/01/24 2014/10/16 rogid:92BjBXGyxALldfF9AVpP+EFN38k9606 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 intact-crc:28B18CCBF040E4D8|rigid:ie3MPAhRrd4yEUGEj5ugNoMlV0U false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A5YKK6 uniprotkb:Q9UKZ1 intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949 intact:EBI-2562014|uniprotkb:Q6P2M9|uniprotkb:Q8N681|ensembl:ENSP00000289382 psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name) psi-mi:cno11_human(display_long)|uniprotkb:CNOT11(gene name)|psi-mi:CNOT11(display_short)|uniprotkb:C2orf29(gene name synonym)|uniprotkb:C40(orf name) psi-mi:"MI:0018"(two hybrid) Mauxion et al. (2012) pubmed:23232451 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6503051 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115 refseq:NP_060016.3|ensembl:ENSG00000158435(gene)|ensembl:ENST00000289382(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR019312|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:5|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/01/24 2014/10/16 rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606 rogid:9OFx7KNPG5R3qVmB8cWCi8VrzKY9606 intact-crc:504B010CCC9F2589|rigid:c/Tc2CZ8+CG0sqpSjHv6nXMlVS0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)