#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13261	uniprotkb:P40933	intact:EBI-980354|uniprotkb:Q5JVA2|uniprotkb:Q6B0J2|uniprotkb:Q5JVA4|uniprotkb:Q7LDR4|ensembl:ENSP00000369312|uniprotkb:Q7Z609|uniprotkb:B4E2C2|uniprotkb:Q5JVA1|uniprotkb:Q3B769	intact:EBI-980274|uniprotkb:O00440|uniprotkb:O43512|uniprotkb:Q495Z8|uniprotkb:Q93058|uniprotkb:Q9UBA3|ensembl:ENSP00000296545|ensembl:ENSP00000323505|ensembl:ENSP00000435462|uniprotkb:D3DNZ2|intact:EBI-3910781|uniprotkb:Q6FGX7	psi-mi:i15ra_human(display_long)|uniprotkb:IL15RA(gene name)|psi-mi:IL15RA(display_short)	psi-mi:il15_human(display_long)|uniprotkb:IL15(gene name)|psi-mi:IL15(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6858800|imex:IM-20994-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134470(gene)|ensembl:ENST00000379977(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR042372|rcsb pdb:2ERS|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_001243694.1|refseq:NP_001230468.1|refseq:NP_002180.1|refseq:NP_751950.2	ensembl:ENSG00000164136(gene)|ensembl:ENST00000296545(transcript)|ensembl:ENST00000320650(transcript)|ensembl:ENST00000529613(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001866"(NK T cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0016607"(nuclear speck)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032819"(positive regulation of natural killer cell proliferation)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034105"(positive regulation of tissue remodeling)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045062"(extrathymic T cell selection)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0048469"(cell maturation)|go:"GO:0007165"(signal transduction)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0048535"(lymph node development)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904100"(positive regulation of protein O-linked glycosylation)|interpro:IPR003443(Interleukin 15)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR020439|interpro:IPR020466|rcsb pdb:2XQB|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_000576.1|refseq:NP_751915.1|dip:DIP-3046N	pdbe:4GS7	-	-	figure legend:Table 1, Fig. 1.|3d-resolution:2.35A|3d-r-factors:Rwork = 19.2  Rfree = 24.2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/08	2014/10/16	rogid:lwiZ6GPZs2SMjWuWJ5NoqgONVAE9606	rogid:Hjoh3ZfpRU0P+xGk7mRhRJJrqkg9606	intact-crc:E42379C4ACC32EC4|rigid:ff0QRMpdm+uE3OezzqnK7u5deP0	false	L-histidine residue:?-?|sufficient binding region:1-67	L-histidine residue:c-c|sufficient binding region:1-114	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13261	uniprotkb:P14784	intact:EBI-980354|uniprotkb:Q5JVA2|uniprotkb:Q6B0J2|uniprotkb:Q5JVA4|uniprotkb:Q7LDR4|ensembl:ENSP00000369312|uniprotkb:Q7Z609|uniprotkb:B4E2C2|uniprotkb:Q5JVA1|uniprotkb:Q3B769	intact:EBI-2866779|uniprotkb:B2R765|ensembl:ENSP00000216223	psi-mi:i15ra_human(display_long)|uniprotkb:IL15RA(gene name)|psi-mi:IL15RA(display_short)	psi-mi:il2rb_human(display_long)|uniprotkb:IL2RB(gene name)|psi-mi:IL2RB(display_short)|uniprotkb:High affinity IL-2 receptor subunit beta(gene name synonym)|uniprotkb:p70-75(gene name synonym)|uniprotkb:Interleukin-15 receptor subunit beta(gene name synonym)|uniprotkb:IL15RB(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6858800|imex:IM-20994-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134470(gene)|ensembl:ENST00000379977(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR042372|rcsb pdb:2ERS|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_001243694.1|refseq:NP_001230468.1|refseq:NP_002180.1|refseq:NP_751950.2	refseq:NP_000869.1|refseq:NP_001333151.1|refseq:NP_001333152.1|dip:DIP-43N|ensembl:ENSG00000100385(gene)|ensembl:ENST00000216223(transcript)|go:"GO:0004911"(interleukin-2 receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005893"(interleukin-2 receptor complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019976"(interleukin-2 binding)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040951|rcsb pdb:1ILM|rcsb pdb:1ILN|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3QAZ|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6E8K|reactome:R-HSA-5673001|reactome:R-HSA-8983432|reactome:R-HSA-9020558|reactome:R-HSA-912526	pdbe:4GS7	-	-	figure legend:Table 1, Fig. 1.|3d-resolution:2.35A|3d-r-factors:Rwork = 19.2  Rfree = 24.2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/08	2014/10/16	rogid:lwiZ6GPZs2SMjWuWJ5NoqgONVAE9606	rogid:fIx5nlom1q65wGMoXZ2SZl3Y4nc9606	intact-crc:E42379C4ACC32EC4|rigid:ff0QRMpdm+uE3OezzqnK7u5deP0	false	L-histidine residue:?-?|sufficient binding region:1-67	sufficient binding region:1-214|mutation:3-3,17-17,45-45|his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13261	uniprotkb:P31785	intact:EBI-980354|uniprotkb:Q5JVA2|uniprotkb:Q6B0J2|uniprotkb:Q5JVA4|uniprotkb:Q7LDR4|ensembl:ENSP00000369312|uniprotkb:Q7Z609|uniprotkb:B4E2C2|uniprotkb:Q5JVA1|uniprotkb:Q3B769	intact:EBI-80475|ensembl:ENSP00000363318|uniprotkb:Q5FC12	psi-mi:i15ra_human(display_long)|uniprotkb:IL15RA(gene name)|psi-mi:IL15RA(display_short)	psi-mi:il2rg_human(display_long)|uniprotkb:IL2RG(gene name)|psi-mi:IL2RG(display_short)|uniprotkb:p64(gene name synonym)|uniprotkb:gammaC(gene name synonym)|uniprotkb:Interleukin-2 receptor subunit gamma(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6858800|imex:IM-20994-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134470(gene)|ensembl:ENST00000379977(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR042372|rcsb pdb:2ERS|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_001243694.1|refseq:NP_001230468.1|refseq:NP_002180.1|refseq:NP_751950.2	ensembl:ENSG00000147168(gene)|ensembl:ENST00000374202(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0019976"(interleukin-2 binding)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0038111"(interleukin-7-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0043235"(receptor complex)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|rcsb pdb:1ILL|rcsb pdb:1ILM|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:1ILN|rcsb pdb:1ITE|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3BPL|rcsb pdb:3QAZ|rcsb pdb:3QB7|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6OEL|reactome:R-HSA-1266695|reactome:R-HSA-5673001|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|reactome:R-HSA-6785807|reactome:R-HSA-8983432|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020958|reactome:R-HSA-912526|refseq:NP_000197.1|dip:DIP-173N	pdbe:4GS7	-	-	figure legend:Table 1, Fig. 1.|3d-resolution:2.35A|3d-r-factors:Rwork = 19.2  Rfree = 24.2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/08	2014/10/16	rogid:lwiZ6GPZs2SMjWuWJ5NoqgONVAE9606	rogid:Fz1gJI4Qk1jAguOQqWXbAWUb/8o9606	intact-crc:E42379C4ACC32EC4|rigid:ff0QRMpdm+uE3OezzqnK7u5deP0	false	L-histidine residue:?-?|sufficient binding region:1-67	sufficient binding region:34-232|mutation:53-53|his tag:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14784	uniprotkb:P40933	intact:EBI-2866779|uniprotkb:B2R765|ensembl:ENSP00000216223	intact:EBI-980274|uniprotkb:O00440|uniprotkb:O43512|uniprotkb:Q495Z8|uniprotkb:Q93058|uniprotkb:Q9UBA3|ensembl:ENSP00000296545|ensembl:ENSP00000323505|ensembl:ENSP00000435462|uniprotkb:D3DNZ2|intact:EBI-3910781|uniprotkb:Q6FGX7	psi-mi:il2rb_human(display_long)|uniprotkb:IL2RB(gene name)|psi-mi:IL2RB(display_short)|uniprotkb:High affinity IL-2 receptor subunit beta(gene name synonym)|uniprotkb:p70-75(gene name synonym)|uniprotkb:Interleukin-15 receptor subunit beta(gene name synonym)|uniprotkb:IL15RB(gene name synonym)	psi-mi:il15_human(display_long)|uniprotkb:IL15(gene name)|psi-mi:IL15(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6858834|imex:IM-20994-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000869.1|refseq:NP_001333151.1|refseq:NP_001333152.1|dip:DIP-43N|ensembl:ENSG00000100385(gene)|ensembl:ENST00000216223(transcript)|go:"GO:0004911"(interleukin-2 receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005893"(interleukin-2 receptor complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019976"(interleukin-2 binding)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040951|rcsb pdb:1ILM|rcsb pdb:1ILN|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3QAZ|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6E8K|reactome:R-HSA-5673001|reactome:R-HSA-8983432|reactome:R-HSA-9020558|reactome:R-HSA-912526	ensembl:ENSG00000164136(gene)|ensembl:ENST00000296545(transcript)|ensembl:ENST00000320650(transcript)|ensembl:ENST00000529613(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001866"(NK T cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0016607"(nuclear speck)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032819"(positive regulation of natural killer cell proliferation)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034105"(positive regulation of tissue remodeling)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045062"(extrathymic T cell selection)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0048469"(cell maturation)|go:"GO:0007165"(signal transduction)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0048535"(lymph node development)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904100"(positive regulation of protein O-linked glycosylation)|interpro:IPR003443(Interleukin 15)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR020439|interpro:IPR020466|rcsb pdb:2XQB|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_000576.1|refseq:NP_751915.1|dip:DIP-3046N	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:438.0x10^-9(molar)	2013/06/08	2015/03/25	rogid:fIx5nlom1q65wGMoXZ2SZl3Y4nc9606	rogid:Hjoh3ZfpRU0P+xGk7mRhRJJrqkg9606	intact-crc:346874F07A435B25|rigid:gQtEyyLHMevirejqqcMZ59Tmprk	false	biotin tag:c-c|sufficient binding region:1-133	his tag:c-c|sufficient binding region:1-114	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14784	uniprotkb:P40933	intact:EBI-2866779|uniprotkb:B2R765|ensembl:ENSP00000216223	intact:EBI-980274|uniprotkb:O00440|uniprotkb:O43512|uniprotkb:Q495Z8|uniprotkb:Q93058|uniprotkb:Q9UBA3|ensembl:ENSP00000296545|ensembl:ENSP00000323505|ensembl:ENSP00000435462|uniprotkb:D3DNZ2|intact:EBI-3910781|uniprotkb:Q6FGX7	psi-mi:il2rb_human(display_long)|uniprotkb:IL2RB(gene name)|psi-mi:IL2RB(display_short)|uniprotkb:High affinity IL-2 receptor subunit beta(gene name synonym)|uniprotkb:p70-75(gene name synonym)|uniprotkb:Interleukin-15 receptor subunit beta(gene name synonym)|uniprotkb:IL15RB(gene name synonym)	psi-mi:il15_human(display_long)|uniprotkb:IL15(gene name)|psi-mi:IL15(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6858840|imex:IM-20994-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000869.1|refseq:NP_001333151.1|refseq:NP_001333152.1|dip:DIP-43N|ensembl:ENSG00000100385(gene)|ensembl:ENST00000216223(transcript)|go:"GO:0004911"(interleukin-2 receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005893"(interleukin-2 receptor complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019976"(interleukin-2 binding)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040951|rcsb pdb:1ILM|rcsb pdb:1ILN|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3QAZ|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6E8K|reactome:R-HSA-5673001|reactome:R-HSA-8983432|reactome:R-HSA-9020558|reactome:R-HSA-912526	ensembl:ENSG00000164136(gene)|ensembl:ENST00000296545(transcript)|ensembl:ENST00000320650(transcript)|ensembl:ENST00000529613(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001866"(NK T cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0016607"(nuclear speck)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032819"(positive regulation of natural killer cell proliferation)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034105"(positive regulation of tissue remodeling)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045062"(extrathymic T cell selection)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0048469"(cell maturation)|go:"GO:0007165"(signal transduction)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0048535"(lymph node development)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904100"(positive regulation of protein O-linked glycosylation)|interpro:IPR003443(Interleukin 15)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR020439|interpro:IPR020466|rcsb pdb:2XQB|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_000576.1|refseq:NP_751915.1|dip:DIP-3046N	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.0x10^-9(molar)	2013/06/08	2015/03/25	rogid:fIx5nlom1q65wGMoXZ2SZl3Y4nc9606	rogid:Hjoh3ZfpRU0P+xGk7mRhRJJrqkg9606	intact-crc:F04448153FF97CED|rigid:MGfvL+GQFodYvOexUTaWwY2lVGY	false	biotin tag:c-c|sufficient binding region:1-133	sufficient binding region:1-114|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P14784	uniprotkb:Q13261	intact:EBI-2866779|uniprotkb:B2R765|ensembl:ENSP00000216223	intact:EBI-980354|uniprotkb:Q5JVA2|uniprotkb:Q6B0J2|uniprotkb:Q5JVA4|uniprotkb:Q7LDR4|ensembl:ENSP00000369312|uniprotkb:Q7Z609|uniprotkb:B4E2C2|uniprotkb:Q5JVA1|uniprotkb:Q3B769	psi-mi:il2rb_human(display_long)|uniprotkb:IL2RB(gene name)|psi-mi:IL2RB(display_short)|uniprotkb:High affinity IL-2 receptor subunit beta(gene name synonym)|uniprotkb:p70-75(gene name synonym)|uniprotkb:Interleukin-15 receptor subunit beta(gene name synonym)|uniprotkb:IL15RB(gene name synonym)	psi-mi:i15ra_human(display_long)|uniprotkb:IL15RA(gene name)|psi-mi:IL15RA(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6858840|imex:IM-20994-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000869.1|refseq:NP_001333151.1|refseq:NP_001333152.1|dip:DIP-43N|ensembl:ENSG00000100385(gene)|ensembl:ENST00000216223(transcript)|go:"GO:0004911"(interleukin-2 receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005893"(interleukin-2 receptor complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019976"(interleukin-2 binding)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040951|rcsb pdb:1ILM|rcsb pdb:1ILN|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3QAZ|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6E8K|reactome:R-HSA-5673001|reactome:R-HSA-8983432|reactome:R-HSA-9020558|reactome:R-HSA-912526	ensembl:ENSG00000134470(gene)|ensembl:ENST00000379977(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR042372|rcsb pdb:2ERS|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_001243694.1|refseq:NP_001230468.1|refseq:NP_002180.1|refseq:NP_751950.2	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.0x10^-9(molar)	2013/06/08	2015/03/25	rogid:fIx5nlom1q65wGMoXZ2SZl3Y4nc9606	rogid:lwiZ6GPZs2SMjWuWJ5NoqgONVAE9606	intact-crc:F04448153FF97CED|rigid:MGfvL+GQFodYvOexUTaWwY2lVGY	false	biotin tag:c-c|sufficient binding region:1-133	sufficient binding region:1-67|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13261	uniprotkb:P40933	intact:EBI-980354|uniprotkb:Q5JVA2|uniprotkb:Q6B0J2|uniprotkb:Q5JVA4|uniprotkb:Q7LDR4|ensembl:ENSP00000369312|uniprotkb:Q7Z609|uniprotkb:B4E2C2|uniprotkb:Q5JVA1|uniprotkb:Q3B769	intact:EBI-980274|uniprotkb:O00440|uniprotkb:O43512|uniprotkb:Q495Z8|uniprotkb:Q93058|uniprotkb:Q9UBA3|ensembl:ENSP00000296545|ensembl:ENSP00000323505|ensembl:ENSP00000435462|uniprotkb:D3DNZ2|intact:EBI-3910781|uniprotkb:Q6FGX7	psi-mi:i15ra_human(display_long)|uniprotkb:IL15RA(gene name)|psi-mi:IL15RA(display_short)	psi-mi:il15_human(display_long)|uniprotkb:IL15(gene name)|psi-mi:IL15(display_short)	psi-mi:"MI:0071"(molecular sieving)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-8699433|imex:IM-20994-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134470(gene)|ensembl:ENST00000379977(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR042372|rcsb pdb:2ERS|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_001243694.1|refseq:NP_001230468.1|refseq:NP_002180.1|refseq:NP_751950.2	ensembl:ENSG00000164136(gene)|ensembl:ENST00000296545(transcript)|ensembl:ENST00000320650(transcript)|ensembl:ENST00000529613(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001866"(NK T cell proliferation)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0016607"(nuclear speck)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032819"(positive regulation of natural killer cell proliferation)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0034105"(positive regulation of tissue remodeling)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045062"(extrathymic T cell selection)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0048469"(cell maturation)|go:"GO:0007165"(signal transduction)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0048535"(lymph node development)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904100"(positive regulation of protein O-linked glycosylation)|interpro:IPR003443(Interleukin 15)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR020439|interpro:IPR020466|rcsb pdb:2XQB|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_000576.1|refseq:NP_751915.1|dip:DIP-3046N	-	-	-	figure legend:Fig. S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/08	2014/10/16	rogid:lwiZ6GPZs2SMjWuWJ5NoqgONVAE9606	rogid:Hjoh3ZfpRU0P+xGk7mRhRJJrqkg9606	intact-crc:8023F19FCDEF93BD|rigid:ff0QRMpdm+uE3OezzqnK7u5deP0	false	L-histidine residue:c-c|sufficient binding region:1-67	L-histidine residue:c-c|sufficient binding region:1-114	1	1	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q13261	uniprotkb:P14784	intact:EBI-980354|uniprotkb:Q5JVA2|uniprotkb:Q6B0J2|uniprotkb:Q5JVA4|uniprotkb:Q7LDR4|ensembl:ENSP00000369312|uniprotkb:Q7Z609|uniprotkb:B4E2C2|uniprotkb:Q5JVA1|uniprotkb:Q3B769	intact:EBI-2866779|uniprotkb:B2R765|ensembl:ENSP00000216223	psi-mi:i15ra_human(display_long)|uniprotkb:IL15RA(gene name)|psi-mi:IL15RA(display_short)	psi-mi:il2rb_human(display_long)|uniprotkb:IL2RB(gene name)|psi-mi:IL2RB(display_short)|uniprotkb:High affinity IL-2 receptor subunit beta(gene name synonym)|uniprotkb:p70-75(gene name synonym)|uniprotkb:Interleukin-15 receptor subunit beta(gene name synonym)|uniprotkb:IL15RB(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-8699433|imex:IM-20994-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134470(gene)|ensembl:ENST00000379977(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR042372|rcsb pdb:2ERS|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_001243694.1|refseq:NP_001230468.1|refseq:NP_002180.1|refseq:NP_751950.2	refseq:NP_000869.1|refseq:NP_001333151.1|refseq:NP_001333152.1|dip:DIP-43N|ensembl:ENSG00000100385(gene)|ensembl:ENST00000216223(transcript)|go:"GO:0004911"(interleukin-2 receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005893"(interleukin-2 receptor complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019976"(interleukin-2 binding)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040951|rcsb pdb:1ILM|rcsb pdb:1ILN|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3QAZ|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6E8K|reactome:R-HSA-5673001|reactome:R-HSA-8983432|reactome:R-HSA-9020558|reactome:R-HSA-912526	-	-	-	figure legend:Fig. S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/08	2014/10/16	rogid:lwiZ6GPZs2SMjWuWJ5NoqgONVAE9606	rogid:fIx5nlom1q65wGMoXZ2SZl3Y4nc9606	intact-crc:8023F19FCDEF93BD|rigid:ff0QRMpdm+uE3OezzqnK7u5deP0	false	L-histidine residue:c-c|sufficient binding region:1-67	sufficient binding region:1-214|his tag:c-c|mutation:3-3,17-17,45-45	1	1	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q13261	uniprotkb:P31785	intact:EBI-980354|uniprotkb:Q5JVA2|uniprotkb:Q6B0J2|uniprotkb:Q5JVA4|uniprotkb:Q7LDR4|ensembl:ENSP00000369312|uniprotkb:Q7Z609|uniprotkb:B4E2C2|uniprotkb:Q5JVA1|uniprotkb:Q3B769	intact:EBI-80475|ensembl:ENSP00000363318|uniprotkb:Q5FC12	psi-mi:i15ra_human(display_long)|uniprotkb:IL15RA(gene name)|psi-mi:IL15RA(display_short)	psi-mi:il2rg_human(display_long)|uniprotkb:IL2RG(gene name)|psi-mi:IL2RG(display_short)|uniprotkb:p64(gene name synonym)|uniprotkb:gammaC(gene name synonym)|uniprotkb:Interleukin-2 receptor subunit gamma(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Ring et al. (2012)	imex:IM-20994|pubmed:23104097	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-8699433|imex:IM-20994-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134470(gene)|ensembl:ENST00000379977(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR042372|rcsb pdb:2ERS|rcsb pdb:2Z3Q|rcsb pdb:2Z3R|rcsb pdb:4GS7|reactome:R-HSA-8983432|refseq:NP_001243694.1|refseq:NP_001230468.1|refseq:NP_002180.1|refseq:NP_751950.2	ensembl:ENSG00000147168(gene)|ensembl:ENST00000374202(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0019976"(interleukin-2 binding)|go:"GO:0035723"(interleukin-15-mediated signaling pathway)|go:"GO:0035771"(interleukin-4-mediated signaling pathway)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0038111"(interleukin-7-mediated signaling pathway)|go:"GO:0042010"(interleukin-15 receptor activity)|go:"GO:0043235"(receptor complex)|go:"GO:0050766"(positive regulation of phagocytosis)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|rcsb pdb:1ILL|rcsb pdb:1ILM|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:1ILN|rcsb pdb:1ITE|rcsb pdb:2B5I|rcsb pdb:2ERJ|rcsb pdb:3BPL|rcsb pdb:3QAZ|rcsb pdb:3QB7|rcsb pdb:4GS7|rcsb pdb:5M5E|rcsb pdb:6OEL|reactome:R-HSA-1266695|reactome:R-HSA-5673001|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|reactome:R-HSA-6785807|reactome:R-HSA-8983432|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020958|reactome:R-HSA-912526|refseq:NP_000197.1|dip:DIP-173N	-	-	-	figure legend:Fig. S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/06/08	2014/10/16	rogid:lwiZ6GPZs2SMjWuWJ5NoqgONVAE9606	rogid:Fz1gJI4Qk1jAguOQqWXbAWUb/8o9606	intact-crc:8023F19FCDEF93BD|rigid:ff0QRMpdm+uE3OezzqnK7u5deP0	false	L-histidine residue:c-c|sufficient binding region:1-67	sufficient binding region:34-232|his tag:c-c|mutation:53-53	1	1	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)