#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:D4A055 uniprotkb:D4A055-1 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 intact:EBI-12632876|ensembl:ENSRNOP00000056186 psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:d4a055-1(display_long)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8028397|mint:MINT-8407324|imex:IM-18759-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407326(identity) intact:EBI-8028403(isoform-parent)|ensembl:ENSRNOG00000007666(gene)|ensembl:ENSRNOT00000059430(transcript)|mint:MINT-8407329(identity) go:"GO:0005634"(nucleus) - - figure legend:f3c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2013/01/08 2016/11/30 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 rogid:aBl9lvQEYnLn+X0jYAH9Z7tL02A10116 intact-crc:9791829785B8B217|rigid:AmDeAla+kdSdQcV/W91ldHHLx7U false binding-associated region:201..201-519(MINT-8407342)|myc tag:?-?(MINT-8407340) binding-associated region:1-166(MINT-8407335)|green fluorescent protein tag:?-?(MINT-8407332) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:D4A055 uniprotkb:Q91V89 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8028443|mint:MINT-8407428|imex:IM-18759-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407430(identity) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407436(identity) go:"GO:0005634"(nucleus) - comment:mint|comment:homomint comment:mint|figure legend:sf3c sf3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2013/01/08 2016/11/30 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 intact-crc:793A4120404D0D09|rigid:f3z8NpZ6y0Z1sEUTnBDef+P9+dc false binding-associated region:483..483-519(MINT-8407433)|green fluorescent protein tag:?-?(MINT-8407431) myc tag:?-?(MINT-8407437) - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:D4A055 uniprotkb:D4A055-2 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 intact:EBI-12685908 psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:d4a055-2(display_long)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8028493|mint:MINT-8407349|imex:IM-18759-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407352(identity) intact:EBI-8028403(isoform-parent)|mint:MINT-8407358(identity) - - - comment:mint|figure legend:f3d f3f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2013/01/08 2016/12/12 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 intact-crc:1B711AF6ECEE3B3F|rigid:dzPIx7qv27jGKFjYHlbLuki7wSk false myc tag:?-?(MINT-8407355)|binding-associated region:201..201-519(MINT-8407353) green fluorescent protein tag:?-?(MINT-8407361)|mutation disrupting interaction strength:125-125(MINT-8407367)|binding-associated region:1..1-134..134(MINT-8407359) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91V89 uniprotkb:P54287 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 intact:EBI-8028596|intact:MINT-8407486|ensembl:ENSRNOP00000073026 psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:cacb3_rat(display_long)|uniprotkb:Cacnb3(gene name)|psi-mi:Cacnb3(display_short)|uniprotkb:Cacnlb3(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8028622|mint:MINT-8407461|imex:IM-18759-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407463(identity) refseq:NP_036960.1|rgd:2248|dip:DIP-59370N|ensembl:ENSRNOG00000054274(gene)|ensembl:ENSRNOT00000081206(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902630"(regulation of membrane hyperpolarization)|go:"GO:1905788"(negative regulation of detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008079(Voltage-dependent calcium channel, L-type, beta-3 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035760|interpro:IPR036028|mint:P54287|rcsb pdb:1VYT|rcsb pdb:1VYU|reactome:R-RNO-112308|reactome:R-RNO-422356|mint:MINT-8407467(identity) - comment:mint|comment:homomint comment:mint figure legend:f4c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/01/08 2014/10/16 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 rogid:qioxo4m/B/2M8vhhTS2urRHOmO010116 intact-crc:31E51DFCDC1691FB|rigid:4ExzFk241J0mIH3cRMi1DdWQT+M false fusion protein:?-?(MINT-8407464) fusion protein:?-?(MINT-8407470) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91V89 uniprotkb:D4A055 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:"MI:0018"(two hybrid) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8028572|mint:MINT-8407379|imex:IM-18759-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407381(identity) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407389(identity) - comment:mint|comment:homomint - comment:mint|figure legend:f4a f4d f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/01/08 2016/11/30 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 intact-crc:176686A1C2577B07|rigid:f3z8NpZ6y0Z1sEUTnBDef+P9+dc false fusion protein:?-?(MINT-8407384) mutation disrupting interaction:125-125(MINT-8407425)|fusion protein:?-?(MINT-8407390)|binding-associated region:483..483-519(MINT-8407392) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63058 uniprotkb:D4A055 intact:EBI-6935292|ensembl:ENSMUSP00000068281|uniprotkb:Q99146|uniprotkb:P10685|uniprotkb:P15827|uniprotkb:P16416|intact:UNK-5501365|intact:MINT-3374329|uniprotkb:Q63196|uniprotkb:Q542U8|uniprotkb:Q63107|uniprotkb:Q63195|uniprotkb:P37241|uniprotkb:Q80Y90|uniprotkb:A3KFN4 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 psi-mi:tha_mouse(display_long)|uniprotkb:Thra(gene name)|psi-mi:Thra(display_short)|uniprotkb:C-erba-alpha(gene name synonym)|uniprotkb:Nr1a1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:c-erbA-1(gene name synonym)|uniprotkb:c-erbA-alpha(gene name synonym) psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:"MI:0018"(two hybrid) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8028666|mint:MINT-8407557|imex:IM-18759-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300912.1|ensembl:ENSMUSG00000058756(gene)|ensembl:ENSMUST00000064187(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009409"(response to cold)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033032"(regulation of myeloid cell apoptotic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2000143"(negative regulation of DNA-templated transcription, initiation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P63058|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|refseq:NP_835161.1|dip:DIP-43752N|mint:MINT-8407559(identity) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407563(identity) - comment:mint|function:Nuclear hormone receptor. High affinity receptor for triiodothyronine - figure legend:f6e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2013/01/08 2016/11/30 rogid:NQpld9X5hOSWJSyhClyYt/u12AY10090 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 intact-crc:7F4440FF964F3F2A|rigid:MO38mwXmymK0HSCfZDcaunLfmxc false fusion protein:?-?(MINT-8407560) fusion protein:?-?(MINT-8407566) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91V89 uniprotkb:D4A055 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8028933|mint:MINT-8407400|imex:IM-18759-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407402(identity) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407406(identity) - comment:mint|comment:homomint - comment:mint|figure legend:f4b f5e sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/08 2016/11/30 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 intact-crc:6BF7DF4C4E04F138|rigid:f3z8NpZ6y0Z1sEUTnBDef+P9+dc false myc tag:?-?(MINT-8407403) green fluorescent protein tag:?-?(MINT-8407407)|binding-associated region:483..483-519(MINT-8407409) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91V89 uniprotkb:D4A055 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8029041|mint:MINT-8407517|imex:IM-18759-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407523(identity) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407521(identity) - comment:mint|comment:homomint - comment:mint|figure legend:f5b f5g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/08 2016/11/30 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 intact-crc:B8E7C3DD98A33A4E|rigid:nUnScCRP8e13ExX+zRs0dM3KF40 false green fluorescent protein tag:?-?(MINT-8407540) myc tag:?-?(MINT-8407537) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q91V89 uniprotkb:P62715 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 intact:EBI-8028975|uniprotkb:P11082|intact:UNK-5382027|ensembl:ENSMUSP00000009774 psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:pp2ab_mouse(display_long)|uniprotkb:Ppp2cb(gene name)|psi-mi:Ppp2cb(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8029041|mint:MINT-8407517|imex:IM-18759-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407523(identity) refseq:NP_059070.1|ensembl:ENSMUSG00000009630(gene)|ensembl:ENSMUST00000009774(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P62715|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-9648025|mint:MINT-8407519(identity) - comment:mint|comment:homomint function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint comment:mint|figure legend:f5b f5g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/08 2016/11/30 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U10090 intact-crc:B8E7C3DD98A33A4E|rigid:nUnScCRP8e13ExX+zRs0dM3KF40 false green fluorescent protein tag:?-?(MINT-8407540) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:D4A055 uniprotkb:P63058 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 intact:EBI-6935292|ensembl:ENSMUSP00000068281|uniprotkb:Q99146|uniprotkb:P10685|uniprotkb:P15827|uniprotkb:P16416|intact:UNK-5501365|intact:MINT-3374329|uniprotkb:Q63196|uniprotkb:Q542U8|uniprotkb:Q63107|uniprotkb:Q63195|uniprotkb:P37241|uniprotkb:Q80Y90|uniprotkb:A3KFN4 psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:tha_mouse(display_long)|uniprotkb:Thra(gene name)|psi-mi:Thra(display_short)|uniprotkb:C-erba-alpha(gene name synonym)|uniprotkb:Nr1a1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group A member 1(gene name synonym)|uniprotkb:c-erbA-1(gene name synonym)|uniprotkb:c-erbA-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8029297|mint:MINT-8407585|imex:IM-18759-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407591(identity) refseq:NP_001300912.1|ensembl:ENSMUSG00000058756(gene)|ensembl:ENSMUST00000064187(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009409"(response to cold)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033032"(regulation of myeloid cell apoptotic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2000143"(negative regulation of DNA-templated transcription, initiation)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P63058|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|refseq:NP_835161.1|dip:DIP-43752N|mint:MINT-8407587(identity) - - comment:mint|function:Nuclear hormone receptor. High affinity receptor for triiodothyronine figure legend:f6f|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/08 2016/11/30 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 rogid:NQpld9X5hOSWJSyhClyYt/u12AY10090 intact-crc:6734F0B7F18D52A8|rigid:MO38mwXmymK0HSCfZDcaunLfmxc false myc tag:?-?(MINT-8407592) green fluorescent protein tag:?-?(MINT-8407588) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q91V89 uniprotkb:Q8R0S4 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 intact:EBI-3647752|uniprotkb:Q3UHK2|uniprotkb:Q8BRN6|uniprotkb:Q8CAJ9|ensembl:ENSMUSP00000077438 psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:cacb4_mouse(display_long)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short)|uniprotkb:Cacnlb4(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8029218|mint:MINT-8407526|imex:IM-18759-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407532(identity) refseq:NP_001272356.1|refseq:XP_011237317.1|refseq:NP_001032176.1|refseq:NP_666235.1|refseq:XP_006497704.1|go:"GO:0045202"(synapse)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|reactome:R-MMU-112308|go:"GO:0042391"(regulation of membrane potential)|ensembl:ENSMUSG00000017412(gene)|ensembl:ENSMUST00000078324(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|refseq:XP_017170652.1|mint:MINT-8407530(identity) - comment:mint|comment:homomint - figure legend:f5f|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/08 2014/10/16 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 rogid:a2B9SMgAy84Ou3mK3Q6aniE71vQ10090 intact-crc:77C0DB0683D6EADD|rigid:6PaE5jo8tAmT8ryX3RztjRaa1q8 false green fluorescent protein tag:?-?(MINT-8407549) myc tag:?-?(MINT-8407552) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:D4A055 uniprotkb:P23198 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 intact:EBI-78162|uniprotkb:Q921C4 psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:cbx3_mouse(display_long)|uniprotkb:Cbx3(gene name)|psi-mi:Cbx3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:M32(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8029386|mint:MINT-8407601|imex:IM-18759-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407603(identity) go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|reactome:R-MMU-73772|reactome:R-MMU-8953750|dip:DIP-28136N|mint:P23198|mint:MINT-8407607(identity) - - - comment:mint|figure legend:f7f f7m|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/08 2016/11/30 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 rogid:mD/Ut3JqLl3k0Ut98GxlstErEGs10090 intact-crc:CFBD012105CF71E8|rigid:yQ5/5MrTXXGjM9qGmniHPbcvMKw false myc tag:?-?(MINT-8407604)|mutation disrupting interaction:222-222(MINT-8407648)|mutation disrupting interaction strength:220-220(MINT-8407645) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:D4A055 uniprotkb:P62806 intact:EBI-8028403|intact:EBI-11620036|intact:MINT-8407327 intact:EBI-299632|ensembl:ENSMUSP00000085006|ensembl:ENSMUSP00000100029|ensembl:ENSMUSP00000100030|ensembl:ENSMUSP00000100032|ensembl:ENSMUSP00000100033|ensembl:ENSMUSP00000100036|ensembl:ENSMUSP00000100037|ensembl:ENSMUSP00000100042|ensembl:ENSMUSP00000100044|ensembl:ENSMUSP00000100048|ensembl:ENSMUSP00000100546|ensembl:ENSMUSP00000129930|ensembl:ENSMUSP00000136357|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q2M2Q5|intact:EBI-302111|uniprotkb:Q6PDS7|uniprotkb:Q811M0|uniprotkb:A0AUM5|uniprotkb:A4FUP8|uniprotkb:A4QMY0|uniprotkb:Q0VDL9|uniprotkb:Q9D0C9|uniprotkb:Q9D6Q8|uniprotkb:Q5T006 psi-mi:cacb4_rat(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short) psi-mi:h4_mouse(display_long)|uniprotkb:H4c11(gene name)|psi-mi:H4c11(display_short)|uniprotkb:H4c12(gene name)|psi-mi:H4c12(display_short)|uniprotkb:H4c14(gene name)|psi-mi:H4c14(display_short)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4c3(gene name)|psi-mi:H4c3(display_short)|uniprotkb:H4c4(gene name)|psi-mi:H4c4(display_short)|uniprotkb:H4c6(gene name)|psi-mi:H4c6(display_short)|uniprotkb:H4c8(gene name)|psi-mi:H4c8(display_short)|uniprotkb:H4c9(gene name)|psi-mi:H4c9(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist1h4a(gene name synonym)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist1h4c(gene name synonym)|uniprotkb:Hist1h4d(gene name synonym)|uniprotkb:Hist1h4f(gene name synonym)|uniprotkb:Hist1h4h(gene name synonym)|uniprotkb:Hist1h4i(gene name synonym)|uniprotkb:Hist1h4j(gene name synonym)|uniprotkb:Hist1h4k(gene name synonym)|uniprotkb:Hist2h4a(gene name synonym)|uniprotkb:Hist2h4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4-53(gene name synonym)|uniprotkb:H4-12(gene name synonym)|uniprotkb:H4c1(gene name)|psi-mi:H4c1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8029475|mint:MINT-8407615|imex:IM-18759-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6HW2|refseq:NP_001099203.1|rgd:68385|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|rcsb pdb:1VYV|reactome:R-RNO-112308|refseq:XP_017447488.1|interpro:IPR036028|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8407621(identity) ensembl:ENSMUSG00000060093(gene)|ensembl:ENSMUSG00000060639(gene)|ensembl:ENSMUSG00000060678(gene)|ensembl:ENSMUSG00000060981(gene)|ensembl:ENSMUSG00000061482(gene)|ensembl:ENSMUSG00000064288(gene)|ensembl:ENSMUSG00000067455(gene)|ensembl:ENSMUSG00000069266(gene)|ensembl:ENSMUSG00000069274(gene)|ensembl:ENSMUSG00000069305(gene)|ensembl:ENSMUSG00000069306(gene)|ensembl:ENSMUSG00000091405(gene)|ensembl:ENSMUST00000087714(transcript)|ensembl:ENSMUST00000102964(transcript)|ensembl:ENSMUST00000102965(transcript)|ensembl:ENSMUST00000102967(transcript)|ensembl:ENSMUST00000102968(transcript)|ensembl:ENSMUST00000102971(transcript)|ensembl:ENSMUST00000102972(transcript)|ensembl:ENSMUST00000102977(transcript)|ensembl:ENSMUST00000102979(transcript)|ensembl:ENSMUST00000102983(transcript)|ensembl:ENSMUST00000104941(transcript)|ensembl:ENSMUST00000171473(transcript)|ensembl:ENSMUST00000179285(transcript)|go:"GO:0000228"(nuclear chromosome)|ensembl:ENSMUSG00000096010(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62806|rcsb pdb:1F66|rcsb pdb:1U35|rcsb pdb:2WP2|go:"GO:0003677"(DNA binding)|rcsb pdb:4AU7|rcsb pdb:4DOW|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-110330|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214842|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-4551638|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_001182350.1|refseq:NP_291074.1|refseq:NP_694813.1|refseq:NP_783583.1|refseq:NP_783585.1|refseq:NP_783586.1|refseq:NP_783587.1|refseq:NP_783588.1|refseq:NP_835499.1|refseq:NP_835500.1|refseq:NP_835515.1|refseq:NP_835582.1|refseq:NP_835583.1|dip:DIP-45837N|mint:MINT-8407617(identity) - - - comment:mint|figure legend:f7i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/08 2016/11/30 rogid:Gy0N9rFnPBvVLHHW+hoShxAhyqA10116 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10090 intact-crc:64770ED037428DB1|rigid:I3JvRGjzpwD3soJ9u18Gfb1aLyo false myc tag:?-?(MINT-8407622) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q91V89 uniprotkb:P62806 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 intact:EBI-299632|ensembl:ENSMUSP00000085006|ensembl:ENSMUSP00000100029|ensembl:ENSMUSP00000100030|ensembl:ENSMUSP00000100032|ensembl:ENSMUSP00000100033|ensembl:ENSMUSP00000100036|ensembl:ENSMUSP00000100037|ensembl:ENSMUSP00000100042|ensembl:ENSMUSP00000100044|ensembl:ENSMUSP00000100048|ensembl:ENSMUSP00000100546|ensembl:ENSMUSP00000129930|ensembl:ENSMUSP00000136357|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q2M2Q5|intact:EBI-302111|uniprotkb:Q6PDS7|uniprotkb:Q811M0|uniprotkb:A0AUM5|uniprotkb:A4FUP8|uniprotkb:A4QMY0|uniprotkb:Q0VDL9|uniprotkb:Q9D0C9|uniprotkb:Q9D6Q8|uniprotkb:Q5T006 psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:h4_mouse(display_long)|uniprotkb:H4c11(gene name)|psi-mi:H4c11(display_short)|uniprotkb:H4c12(gene name)|psi-mi:H4c12(display_short)|uniprotkb:H4c14(gene name)|psi-mi:H4c14(display_short)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4c3(gene name)|psi-mi:H4c3(display_short)|uniprotkb:H4c4(gene name)|psi-mi:H4c4(display_short)|uniprotkb:H4c6(gene name)|psi-mi:H4c6(display_short)|uniprotkb:H4c8(gene name)|psi-mi:H4c8(display_short)|uniprotkb:H4c9(gene name)|psi-mi:H4c9(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist1h4a(gene name synonym)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist1h4c(gene name synonym)|uniprotkb:Hist1h4d(gene name synonym)|uniprotkb:Hist1h4f(gene name synonym)|uniprotkb:Hist1h4h(gene name synonym)|uniprotkb:Hist1h4i(gene name synonym)|uniprotkb:Hist1h4j(gene name synonym)|uniprotkb:Hist1h4k(gene name synonym)|uniprotkb:Hist2h4a(gene name synonym)|uniprotkb:Hist2h4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4-53(gene name synonym)|uniprotkb:H4-12(gene name synonym)|uniprotkb:H4c1(gene name)|psi-mi:H4c1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8029507|mint:MINT-8407629|imex:IM-18759-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407633(identity) ensembl:ENSMUSG00000060093(gene)|ensembl:ENSMUSG00000060639(gene)|ensembl:ENSMUSG00000060678(gene)|ensembl:ENSMUSG00000060981(gene)|ensembl:ENSMUSG00000061482(gene)|ensembl:ENSMUSG00000064288(gene)|ensembl:ENSMUSG00000067455(gene)|ensembl:ENSMUSG00000069266(gene)|ensembl:ENSMUSG00000069274(gene)|ensembl:ENSMUSG00000069305(gene)|ensembl:ENSMUSG00000069306(gene)|ensembl:ENSMUSG00000091405(gene)|ensembl:ENSMUST00000087714(transcript)|ensembl:ENSMUST00000102964(transcript)|ensembl:ENSMUST00000102965(transcript)|ensembl:ENSMUST00000102967(transcript)|ensembl:ENSMUST00000102968(transcript)|ensembl:ENSMUST00000102971(transcript)|ensembl:ENSMUST00000102972(transcript)|ensembl:ENSMUST00000102977(transcript)|ensembl:ENSMUST00000102979(transcript)|ensembl:ENSMUST00000102983(transcript)|ensembl:ENSMUST00000104941(transcript)|ensembl:ENSMUST00000171473(transcript)|ensembl:ENSMUST00000179285(transcript)|go:"GO:0000228"(nuclear chromosome)|ensembl:ENSMUSG00000096010(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62806|rcsb pdb:1F66|rcsb pdb:1U35|rcsb pdb:2WP2|go:"GO:0003677"(DNA binding)|rcsb pdb:4AU7|rcsb pdb:4DOW|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-110330|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214842|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-4551638|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_001182350.1|refseq:NP_291074.1|refseq:NP_694813.1|refseq:NP_783583.1|refseq:NP_783585.1|refseq:NP_783586.1|refseq:NP_783587.1|refseq:NP_783588.1|refseq:NP_835499.1|refseq:NP_835500.1|refseq:NP_835515.1|refseq:NP_835582.1|refseq:NP_835583.1|dip:DIP-45837N|mint:MINT-8407631(identity) - comment:mint|comment:homomint - comment:homomint|comment:mint|figure legend:f7k|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2013/01/08 2014/10/16 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10090 intact-crc:F1E46FB4AB02F908|rigid:/H/CSnKPO2PfybwIfLTPazIIF44 false myc tag:?-?(MINT-8407634) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8R0S4 uniprotkb:Q91V89 intact:EBI-3647752|uniprotkb:Q3UHK2|uniprotkb:Q8BRN6|uniprotkb:Q8CAJ9|ensembl:ENSMUSP00000077438 intact:EBI-8028449|intact:MINT-4120882|ensembl:ENSMUSP00000002839 psi-mi:cacb4_mouse(display_long)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short)|uniprotkb:Cacnlb4(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym) psi-mi:q91v89_mouse(display_long)|uniprotkb:Ppp2r5d(gene name)|psi-mi:Ppp2r5d(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8029571|mint:MINT-8407497|imex:IM-18759-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272356.1|refseq:XP_011237317.1|refseq:NP_001032176.1|refseq:NP_666235.1|refseq:XP_006497704.1|go:"GO:0045202"(synapse)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|reactome:R-MMU-112308|go:"GO:0042391"(regulation of membrane potential)|ensembl:ENSMUSG00000017412(gene)|ensembl:ENSMUST00000078324(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|refseq:XP_017170652.1|mint:MINT-8407499(identity) refseq:NP_033384.2|ensembl:ENSMUSG00000059409(gene)|ensembl:ENSMUST00000002839(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q91V89|mint:MINT-8407505(identity) - - comment:mint|comment:homomint figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2013/01/08 2014/10/16 rogid:a2B9SMgAy84Ou3mK3Q6aniE71vQ10090 rogid:Z7/tVWPmOXI1gR+X3Q5EktUJRz810090 intact-crc:8C7F70616189CD4C|rigid:XKWZDSyTPwwprWZbpBQm89nanHg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8R0S4 uniprotkb:P62715 intact:EBI-3647752|uniprotkb:Q3UHK2|uniprotkb:Q8BRN6|uniprotkb:Q8CAJ9|ensembl:ENSMUSP00000077438 intact:EBI-8028975|uniprotkb:P11082|intact:UNK-5382027|ensembl:ENSMUSP00000009774 psi-mi:cacb4_mouse(display_long)|uniprotkb:Cacnb4(gene name)|psi-mi:Cacnb4(display_short)|uniprotkb:Cacnlb4(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 4(gene name synonym) psi-mi:pp2ab_mouse(display_long)|uniprotkb:Ppp2cb(gene name)|psi-mi:Ppp2cb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tadmouri et al. (2012) pubmed:22892567|imex:IM-18759|mint:MINT-8407318 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8029571|mint:MINT-8407497|imex:IM-18759-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272356.1|refseq:XP_011237317.1|refseq:NP_001032176.1|refseq:NP_666235.1|refseq:XP_006497704.1|go:"GO:0045202"(synapse)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050877"(nervous system process)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0055001"(muscle cell development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|reactome:R-MMU-112308|go:"GO:0042391"(regulation of membrane potential)|ensembl:ENSMUSG00000017412(gene)|ensembl:ENSMUST00000078324(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0016607"(nuclear speck)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035249"(synaptic transmission, glutamatergic)|refseq:XP_017170652.1|mint:MINT-8407499(identity) refseq:NP_059070.1|ensembl:ENSMUSG00000009630(gene)|ensembl:ENSMUST00000009774(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P62715|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-9648025|mint:MINT-8407510(identity) - - function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint figure legend:f5a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2013/01/08 2014/10/16 rogid:a2B9SMgAy84Ou3mK3Q6aniE71vQ10090 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U10090 intact-crc:8C7F70616189CD4C|rigid:XKWZDSyTPwwprWZbpBQm89nanHg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)