#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P27958-PRO_0000037573	uniprotkb:P28062	intact:EBI-3649474|intact:EBI-6904428	intact:EBI-372294|uniprotkb:Q29824|uniprotkb:Q96J48|uniprotkb:Q5JNW6|uniprotkb:B0UZC0|ensembl:ENSP00000364016|ensembl:ENSP00000372723|ensembl:ENSP00000394155|ensembl:ENSP00000402406|ensembl:ENSP00000404585|ensembl:ENSP00000406797|ensembl:ENSP00000414770|intact:EBI-780761|uniprotkb:Q5QNR8	psi-mi:p27958-pro_0000037573(display_long)	psi-mi:psb8_human(display_long)|uniprotkb:PSMB8(gene name)|psi-mi:PSMB8(display_short)|uniprotkb:LMP7(gene name synonym)|uniprotkb:RING10(gene name synonym)|uniprotkb:Y2(gene name synonym)|uniprotkb:Proteasome subunit beta-5i(gene name synonym)|uniprotkb:Proteasome component C13(gene name synonym)|uniprotkb:Macropain subunit C13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C13(gene name synonym)|uniprotkb:Low molecular mass protein 7(gene name synonym)|uniprotkb:PSMB5i(gene name synonym)|uniprotkb:Really interesting new gene 10 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Khu et al. (2004)	pubmed:15303969|imex:IM-25889	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6671778|imex:IM-25889-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5L5B|ensembl:ENSG00000204264(gene)|ensembl:ENSG00000206298(gene)|ensembl:ENSG00000226201(gene)|ensembl:ENSG00000230669(gene)|ensembl:ENSG00000231631(gene)|ensembl:ENSG00000235715(gene)|ensembl:ENSG00000236443(gene)|ensembl:ENST00000374882(transcript)|ensembl:ENST00000383236(transcript)|ensembl:ENST00000421445(transcript)|ensembl:ENST00000429645(transcript)|ensembl:ENST00000438442(transcript)|ensembl:ENST00000455660(transcript)|ensembl:ENST00000457261(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035705|rcsb pdb:5L5A|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-174178|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-909733|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5687128|refseq:NP_004150.1|refseq:NP_683720.2	-	chain-seq-start:1027|chain-seq-end:1657	-	figure legend:1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2017/09/02	rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746	rogid:XSNs073UKpjwL4TejKS9mczVX9I9606	intact-crc:00E6CB079BF75767|rigid:jE/yw68Ei13Bje9KLGi2KWinCac	false	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P27958-PRO_0000037573	uniprotkb:P25789	intact:EBI-3649474|intact:EBI-6904428	intact:EBI-359310|uniprotkb:Q8TBD1|uniprotkb:Q53XP2|ensembl:ENSP00000044462|ensembl:ENSP00000453887|uniprotkb:D3DW86|uniprotkb:Q567Q5	psi-mi:p27958-pro_0000037573(display_long)	psi-mi:psa4_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)|uniprotkb:PSC9(gene name synonym)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:HC9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Khu et al. (2004)	pubmed:15303969|imex:IM-25889	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6671824|imex:IM-25889-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)|go:"GO:0070628"(proteasome binding)	refseq:NP_001096137.1|refseq:NP_002780.1|rcsb pdb:6XMJ|reactome:R-HSA-2467813|reactome:R-HSA-2871837|rcsb pdb:7AWE|reactome:R-HSA-349425|reactome:R-HSA-1169091|reactome:R-HSA-350562|reactome:R-HSA-1234176|reactome:R-HSA-382556|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-450408|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5358346|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000041357(gene)|ensembl:ENST00000044462(transcript)|ensembl:ENST00000559082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:P25789|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|refseq:NP_001096138.1|refseq:NP_001317605.1|dip:DIP-29365N|go:"GO:0000502"(proteasome complex)	-	chain-seq-start:1027|chain-seq-end:1657	-	figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2013/05/10	2017/09/02	rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746	rogid:u+wKxvIa9JKb4Zu9K+tnY3d26tw9606	intact-crc:A3B7ACB023E9C64E|rigid:Z1J6IDl6MAGIyLGGsy4ZVSLYAvI	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P27958-PRO_0000037573	uniprotkb:P28062	intact:EBI-3649474|intact:EBI-6904428	intact:EBI-372294|uniprotkb:Q29824|uniprotkb:Q96J48|uniprotkb:Q5JNW6|uniprotkb:B0UZC0|ensembl:ENSP00000364016|ensembl:ENSP00000372723|ensembl:ENSP00000394155|ensembl:ENSP00000402406|ensembl:ENSP00000404585|ensembl:ENSP00000406797|ensembl:ENSP00000414770|intact:EBI-780761|uniprotkb:Q5QNR8	psi-mi:p27958-pro_0000037573(display_long)	psi-mi:psb8_human(display_long)|uniprotkb:PSMB8(gene name)|psi-mi:PSMB8(display_short)|uniprotkb:LMP7(gene name synonym)|uniprotkb:RING10(gene name synonym)|uniprotkb:Y2(gene name synonym)|uniprotkb:Proteasome subunit beta-5i(gene name synonym)|uniprotkb:Proteasome component C13(gene name synonym)|uniprotkb:Macropain subunit C13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C13(gene name synonym)|uniprotkb:Low molecular mass protein 7(gene name synonym)|uniprotkb:PSMB5i(gene name synonym)|uniprotkb:Really interesting new gene 10 protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Khu et al. (2004)	pubmed:15303969|imex:IM-25889	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6671720|imex:IM-25889-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5L5B|ensembl:ENSG00000204264(gene)|ensembl:ENSG00000206298(gene)|ensembl:ENSG00000226201(gene)|ensembl:ENSG00000230669(gene)|ensembl:ENSG00000231631(gene)|ensembl:ENSG00000235715(gene)|ensembl:ENSG00000236443(gene)|ensembl:ENST00000374882(transcript)|ensembl:ENST00000383236(transcript)|ensembl:ENST00000421445(transcript)|ensembl:ENST00000429645(transcript)|ensembl:ENST00000438442(transcript)|ensembl:ENST00000455660(transcript)|ensembl:ENST00000457261(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035705|rcsb pdb:5L5A|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-174178|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-909733|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5687128|refseq:NP_004150.1|refseq:NP_683720.2	-	chain-seq-start:1027|chain-seq-end:1657	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2013/05/10	2014/10/16	rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746	rogid:XSNs073UKpjwL4TejKS9mczVX9I9606	intact-crc:F3700B2AC0A98784|rigid:jE/yw68Ei13Bje9KLGi2KWinCac	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P27958-PRO_0000037573	uniprotkb:P28062	intact:EBI-3649474|intact:EBI-6904428	intact:EBI-372294|uniprotkb:Q29824|uniprotkb:Q96J48|uniprotkb:Q5JNW6|uniprotkb:B0UZC0|ensembl:ENSP00000364016|ensembl:ENSP00000372723|ensembl:ENSP00000394155|ensembl:ENSP00000402406|ensembl:ENSP00000404585|ensembl:ENSP00000406797|ensembl:ENSP00000414770|intact:EBI-780761|uniprotkb:Q5QNR8	psi-mi:p27958-pro_0000037573(display_long)	psi-mi:psb8_human(display_long)|uniprotkb:PSMB8(gene name)|psi-mi:PSMB8(display_short)|uniprotkb:LMP7(gene name synonym)|uniprotkb:RING10(gene name synonym)|uniprotkb:Y2(gene name synonym)|uniprotkb:Proteasome subunit beta-5i(gene name synonym)|uniprotkb:Proteasome component C13(gene name synonym)|uniprotkb:Macropain subunit C13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C13(gene name synonym)|uniprotkb:Low molecular mass protein 7(gene name synonym)|uniprotkb:PSMB5i(gene name synonym)|uniprotkb:Really interesting new gene 10 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Khu et al. (2004)	pubmed:15303969|imex:IM-25889	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6671795|imex:IM-25889-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5L5B|ensembl:ENSG00000204264(gene)|ensembl:ENSG00000206298(gene)|ensembl:ENSG00000226201(gene)|ensembl:ENSG00000230669(gene)|ensembl:ENSG00000231631(gene)|ensembl:ENSG00000235715(gene)|ensembl:ENSG00000236443(gene)|ensembl:ENST00000374882(transcript)|ensembl:ENST00000383236(transcript)|ensembl:ENST00000421445(transcript)|ensembl:ENST00000429645(transcript)|ensembl:ENST00000438442(transcript)|ensembl:ENST00000455660(transcript)|ensembl:ENST00000457261(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035705|rcsb pdb:5L5A|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-174178|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-909733|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5687128|refseq:NP_004150.1|refseq:NP_683720.2	-	chain-seq-start:1027|chain-seq-end:1657	-	figure legend:2|comment:"NS3 N-terminal protease region (aa1-245) interact with LMP7 (fig 2B).  LMP7 N-terminal pro-sequence region (aa1-40) interact with NS3 (fig 3C)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/05/10	2017/09/02	rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746	rogid:XSNs073UKpjwL4TejKS9mczVX9I9606	intact-crc:A20158561FAA6C84|rigid:jE/yw68Ei13Bje9KLGi2KWinCac	false	necessary binding region:1-180|flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P27958-PRO_0000037573	uniprotkb:P28062	intact:EBI-3649474|intact:EBI-6904428	intact:EBI-372294|uniprotkb:Q29824|uniprotkb:Q96J48|uniprotkb:Q5JNW6|uniprotkb:B0UZC0|ensembl:ENSP00000364016|ensembl:ENSP00000372723|ensembl:ENSP00000394155|ensembl:ENSP00000402406|ensembl:ENSP00000404585|ensembl:ENSP00000406797|ensembl:ENSP00000414770|intact:EBI-780761|uniprotkb:Q5QNR8	psi-mi:p27958-pro_0000037573(display_long)	psi-mi:psb8_human(display_long)|uniprotkb:PSMB8(gene name)|psi-mi:PSMB8(display_short)|uniprotkb:LMP7(gene name synonym)|uniprotkb:RING10(gene name synonym)|uniprotkb:Y2(gene name synonym)|uniprotkb:Proteasome subunit beta-5i(gene name synonym)|uniprotkb:Proteasome component C13(gene name synonym)|uniprotkb:Macropain subunit C13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C13(gene name synonym)|uniprotkb:Low molecular mass protein 7(gene name synonym)|uniprotkb:PSMB5i(gene name synonym)|uniprotkb:Really interesting new gene 10 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Khu et al. (2004)	pubmed:15303969|imex:IM-25889	taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-6677851|imex:IM-25889-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-706378(chain-parent)	rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5L5B|ensembl:ENSG00000204264(gene)|ensembl:ENSG00000206298(gene)|ensembl:ENSG00000226201(gene)|ensembl:ENSG00000230669(gene)|ensembl:ENSG00000231631(gene)|ensembl:ENSG00000235715(gene)|ensembl:ENSG00000236443(gene)|ensembl:ENST00000374882(transcript)|ensembl:ENST00000383236(transcript)|ensembl:ENST00000421445(transcript)|ensembl:ENST00000429645(transcript)|ensembl:ENST00000438442(transcript)|ensembl:ENST00000455660(transcript)|ensembl:ENST00000457261(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035705|rcsb pdb:5L5A|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-174178|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-909733|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5687128|refseq:NP_004150.1|refseq:NP_683720.2	-	chain-seq-start:1027|chain-seq-end:1657	-	figure legend:3|comment:"NS3 N-terminal protease region (aa1-245) interact with LMP7 (fig 2B).  LMP7 N-terminal pro-sequence region (aa1-40) interact with NS3 (fig 3C)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2013/05/10	2014/10/16	rogid:LZKhRVu6emlYHQVy91L9hPlY9Mw63746	rogid:XSNs073UKpjwL4TejKS9mczVX9I9606	intact-crc:38513AE06404EFF5|rigid:jE/yw68Ei13Bje9KLGi2KWinCac	false	flag tag:?-?	myc tag:?-?|necessary binding region:1-40	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)