#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P12815-2 uniprotkb:P12815-2 intact:EBI-9117858|ensembl:ENSMUSP00000152458 intact:EBI-9117858|ensembl:ENSMUSP00000152458 psi-mi:p12815-2(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,1(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:p12815-2(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,1(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tarabykina et al. (2000) pubmed:10744743|imex:IM-20986 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6900195|imex:IM-20986-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000222759(transcript) intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000222759(transcript) - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/07/23 2014/10/16 rogid:6eA7l1QjdIieCz6pOUr9w0bwmN410090 rogid:6eA7l1QjdIieCz6pOUr9w0bwmN410090 intact-crc:D6059163A0FAC235|rigid:o208zqeYzc7l7jhk1tY6NnmEeiU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12815-1 uniprotkb:Q9WU78 intact:EBI-9247374|ensembl:ENSMUSP00000022060 intact:EBI-641897|uniprotkb:Q3TED2|uniprotkb:O88695|uniprotkb:O89014|uniprotkb:Q8BSL8|uniprotkb:Q8R0H5|uniprotkb:Q99LR3|uniprotkb:Q9QZN8|ensembl:ENSMUSP00000035086 psi-mi:p12815-1(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,5(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:pdc6i_mouse(display_long)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tarabykina et al. (2000) pubmed:10744743|imex:IM-20986 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9247391|imex:IM-20986-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript) refseq:NP_001158149.1|refseq:NP_001158150.1|refseq:NP_035182.2|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:0043209"(myelin sheath)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q9WU78|reactome:R-MMU-5213460|reactome:R-MMU-5675482|dip:DIP-41418N - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/07/23 2014/10/16 rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 intact-crc:96AF9C18AFB15F7F|rigid:8dW1tFKJMD4S6On/k0a9XK9z6xY false - sufficient binding region:467-869 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12815-1 uniprotkb:P12815-1 intact:EBI-9247374|ensembl:ENSMUSP00000022060 intact:EBI-9247374|ensembl:ENSMUSP00000022060 psi-mi:p12815-1(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,5(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:p12815-1(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,5(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tarabykina et al. (2000) pubmed:10744743|imex:IM-20986 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6900199|imex:IM-20986-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript) intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript) - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/07/23 2014/10/16 rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090 rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090 intact-crc:C2D6979DAED7C9E5|rigid:+OsFsMk0ErcAG7eFb4nOc8j1HzI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12815-1 uniprotkb:P12815-2 intact:EBI-9247374|ensembl:ENSMUSP00000022060 intact:EBI-9117858|ensembl:ENSMUSP00000152458 psi-mi:p12815-1(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,5(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:p12815-2(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,1(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tarabykina et al. (2000) pubmed:10744743|imex:IM-20986 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6900203|imex:IM-20986-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript) intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000222759(transcript) - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2013/07/23 2014/10/16 rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090 rogid:6eA7l1QjdIieCz6pOUr9w0bwmN410090 intact-crc:AD5BE50D51E59446|rigid:myi4Jqs3dosTcTVCWBcy4x06HZQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) chebi:"CHEBI:29108" uniprotkb:P12815-1 intact:EBI-1169353 intact:EBI-9247374|ensembl:ENSMUSP00000022060 psi-mi:"calcium(2+)"(display_short)|psi-mi:"CHEBI:29108"(display_long) psi-mi:p12815-1(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,5(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:"MI:1086"(equilibrium dialysis) Tarabykina et al. (2000) pubmed:10744743|imex:IM-20986 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6900376|imex:IM-20986-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000022060(transcript) - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.2x10^-6(molar) 2013/07/23 2020/02/18 - rogid:JgwCqMEgIZ12mnBk898EvUlOQOc10090 intact-crc:D3EB0853567C6170 false - - 3 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:29108" uniprotkb:P12815-2 intact:EBI-1169353 intact:EBI-9117858|ensembl:ENSMUSP00000152458 psi-mi:"calcium(2+)"(display_short)|psi-mi:"CHEBI:29108"(display_long) psi-mi:p12815-2(display_long)|uniprotkb:Apoptosis-linked gene 2 protein(gene name synonym)|uniprotkb:ALG-2,1(isoform synonym)|uniprotkb:Pdcd6(gene name)|psi-mi:Pdcd6(display_short)|uniprotkb:Alg2(gene name synonym)|uniprotkb:ALG-257(gene name synonym)|uniprotkb:PMP41(gene name synonym) psi-mi:"MI:1086"(equilibrium dialysis) Tarabykina et al. (2000) pubmed:10744743|imex:IM-20986 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6900482|imex:IM-20986-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-309164(isoform-parent)|ensembl:ENSMUSG00000021576(gene)|ensembl:ENSMUST00000222759(transcript) - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.1x10^-6(molar) 2013/07/23 2020/02/18 - rogid:6eA7l1QjdIieCz6pOUr9w0bwmN410090 intact-crc:C268543666DBD9E3 false - - 3 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)