#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:G5EEH9 uniprotkb:O02333 intact:EBI-6455549|ensemblmetazoa:ZK328.5b.1|uniprotkb:D1MN48|uniprotkb:H2L014 intact:EBI-328275|ensemblmetazoa:T24D1.3.1|ensemblmetazoa:T24D1.3.2 psi-mi:nup98_caeel(display_long)|uniprotkb:ZK328.5(orf name)|uniprotkb:npp-10(gene name)|psi-mi:npp-10(display_short) psi-mi:o02333_caeel(display_long)|uniprotkb:T24D1.3(orf name)|uniprotkb:CELE_T24D1.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455546|imex:IM-11985-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003796(gene)|ensemblmetazoa:ZK328.5b.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030719"(P granule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043186"(P granule)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|refseq:NP_001254934.1|refseq:NP_498309.3|refseq:NP_498310.3|wormbase:ZK328.5a|wormbase:ZK328.5b|wormbase:ZK328.5c|interpro:IPR036903|interpro:IPR037665|reactome:R-CEL-9615933|interpro:IPR037637 interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_492633.1|wormbase:T24D1.3|ensemblmetazoa:T24D1.3.1(transcript)|ensemblmetazoa:T24D1.3.2(transcript)|ensemblmetazoa:WBGene00011986(gene)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Xj7pumBXLbULLptjYCn0wOPY2zs6239 rogid:SvxznKvVTU+v7MJB9Rgh0eSW7Mg6239 intact-crc:2A20A41B3956E28C|rigid:5PslaIAERUUaequj6trpTxNwgx8 false sufficient binding region:490-981("MI:0442") sufficient binding region:51-349("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17071 uniprotkb:O17071 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455533|imex:IM-11985-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 intact-crc:0B186BEEB262ED15|rigid:uvcVIg3emySV9m6Yp8iS+TgtHpI false sufficient binding region:8-406("MI:0442") sufficient binding region:9-406("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44548 uniprotkb:Q21443 intact:EBI-2002279|ensemblmetazoa:K06A5.4.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:knl2_caeel(display_long)|uniprotkb:knl-2(gene name)|psi-mi:knl-2(display_short)|uniprotkb:K06A5.4(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455593|imex:IM-11985-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015216(SANT associated)|refseq:NP_491858.1|wormbase:K06A5.4|interpro:IPR044895|rcsb pdb:2M3A|interpro:IPR039110|ensemblmetazoa:K06A5.4.1(transcript)|ensemblmetazoa:WBGene00019432(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:75DxENUtFsHh+zV4+If5DTMKOjI6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:B4184D3C1AA200D2|rigid:AOlSuKZO0ZLCZ69/vFbSq2mzxKE false sufficient binding region:1-876("MI:0442") sufficient binding region:251-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEH9 uniprotkb:G5ECG0 intact:EBI-6455549|ensemblmetazoa:ZK328.5b.1|uniprotkb:D1MN48|uniprotkb:H2L014 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:nup98_caeel(display_long)|uniprotkb:ZK328.5(orf name)|uniprotkb:npp-10(gene name)|psi-mi:npp-10(display_short) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455567|imex:IM-11985-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003796(gene)|ensemblmetazoa:ZK328.5b.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030719"(P granule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043186"(P granule)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|refseq:NP_001254934.1|refseq:NP_498309.3|refseq:NP_498310.3|wormbase:ZK328.5a|wormbase:ZK328.5b|wormbase:ZK328.5c|interpro:IPR036903|interpro:IPR037665|reactome:R-CEL-9615933|interpro:IPR037637 interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Xj7pumBXLbULLptjYCn0wOPY2zs6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:70F3C7B5354465DF|rigid:KSqxq9o/yT1W501yuJ5fpNZFoK4 false sufficient binding region:490-981("MI:0442") sufficient binding region:34-260("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEH9 uniprotkb:Q21443 intact:EBI-6455549|ensemblmetazoa:ZK328.5b.1|uniprotkb:D1MN48|uniprotkb:H2L014 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:nup98_caeel(display_long)|uniprotkb:ZK328.5(orf name)|uniprotkb:npp-10(gene name)|psi-mi:npp-10(display_short) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455606|imex:IM-11985-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003796(gene)|ensemblmetazoa:ZK328.5b.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030719"(P granule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043186"(P granule)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|refseq:NP_001254934.1|refseq:NP_498309.3|refseq:NP_498310.3|wormbase:ZK328.5a|wormbase:ZK328.5b|wormbase:ZK328.5c|interpro:IPR036903|interpro:IPR037665|reactome:R-CEL-9615933|interpro:IPR037637 reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Xj7pumBXLbULLptjYCn0wOPY2zs6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:420AE2AFF0DAC735|rigid:SQNQyZg8ljqjp+vxM9TY2Jfzxq4 false sufficient binding region:490-981("MI:0442") sufficient binding region:251-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEH9 uniprotkb:P91457 intact:EBI-6455549|ensemblmetazoa:ZK328.5b.1|uniprotkb:D1MN48|uniprotkb:H2L014 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:nup98_caeel(display_long)|uniprotkb:ZK328.5(orf name)|uniprotkb:npp-10(gene name)|psi-mi:npp-10(display_short) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455580|imex:IM-11985-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003796(gene)|ensemblmetazoa:ZK328.5b.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030719"(P granule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043186"(P granule)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|refseq:NP_001254934.1|refseq:NP_498309.3|refseq:NP_498310.3|wormbase:ZK328.5a|wormbase:ZK328.5b|wormbase:ZK328.5c|interpro:IPR036903|interpro:IPR037665|reactome:R-CEL-9615933|interpro:IPR037637 refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Xj7pumBXLbULLptjYCn0wOPY2zs6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:62C6E58D4432DE34|rigid:1NkMDQQ/Mj2PjjHzc7vbqyNc+k8 false sufficient binding region:490-981("MI:0442") sufficient binding region:336-470("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 intact:EBI-2003647 intact:EBI-313007|ensemblmetazoa:B0547.1.1 - psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:o44487_caeel(display_short)|psi-mi:EBI-2003647(display_long)|uniprotkb:F42A6.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455632|imex:IM-11985-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 uniprotkb:O44487(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:z8Q+9aSJhEoo7St1cCL6j/FVcto6239 intact-crc:3C044AA4BDE7CD5E|rigid:wFEnUH9Oq8jc7rQ4KBRcxAjXvzw false sufficient binding region:18-368("MI:0442") sufficient binding region:1-146("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TA83 uniprotkb:G5EEH9 intact:EBI-331999|uniprotkb:P34408|uniprotkb:Q95QJ6|ensemblmetazoa:F22B7.5a.1 intact:EBI-6455549|ensemblmetazoa:ZK328.5b.1|uniprotkb:D1MN48|uniprotkb:H2L014 psi-mi:dnj10_caeel(display_long)|uniprotkb:F22B7.5(orf name)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short) psi-mi:nup98_caeel(display_long)|uniprotkb:ZK328.5(orf name)|uniprotkb:npp-10(gene name)|psi-mi:npp-10(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455645|imex:IM-11985-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498901.1|refseq:NP_498902.1|wormbase:F22B7.5a|wormbase:F22B7.5b|dip:DIP-24664N|ensemblmetazoa:F22B7.5a.1(transcript)|ensemblmetazoa:WBGene00001028(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009408"(response to heat)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 ensemblmetazoa:WBGene00003796(gene)|ensemblmetazoa:ZK328.5b.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030719"(P granule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043186"(P granule)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|refseq:NP_001254934.1|refseq:NP_498309.3|refseq:NP_498310.3|wormbase:ZK328.5a|wormbase:ZK328.5b|wormbase:ZK328.5c|interpro:IPR036903|interpro:IPR037665|reactome:R-CEL-9615933|interpro:IPR037637 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:rZSB2nN04hE44ryl282RwGo9QqQ6239 rogid:Xj7pumBXLbULLptjYCn0wOPY2zs6239 intact-crc:50D78BC110BF065D|rigid:t/oqGCZ9lz+c05iCFIMNKJIerp0 false sufficient binding region:151-294("MI:0442") sufficient binding region:490-981("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEH9 uniprotkb:P91400 intact:EBI-6455549|ensemblmetazoa:ZK328.5b.1|uniprotkb:D1MN48|uniprotkb:H2L014 intact:EBI-325226|ensemblmetazoa:M01E11.6.1|ensemblmetazoa:M01E11.6.2 psi-mi:nup98_caeel(display_long)|uniprotkb:ZK328.5(orf name)|uniprotkb:npp-10(gene name)|psi-mi:npp-10(display_short) psi-mi:p91400_caeel(display_long)|uniprotkb:klp-15(gene name)|psi-mi:klp-15(display_short)|uniprotkb:CELE_M01E11.6(orf name)|uniprotkb:M01E11.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455658|imex:IM-11985-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003796(gene)|ensemblmetazoa:ZK328.5b.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030719"(P granule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043186"(P granule)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|refseq:NP_001254934.1|refseq:NP_498309.3|refseq:NP_498310.3|wormbase:ZK328.5a|wormbase:ZK328.5b|wormbase:ZK328.5c|interpro:IPR036903|interpro:IPR037665|reactome:R-CEL-9615933|interpro:IPR037637 refseq:NP_491633.1|wormbase:M01E11.6|ensemblmetazoa:M01E11.6.1(transcript)|ensemblmetazoa:M01E11.6.2(transcript)|ensemblmetazoa:WBGene00002225(gene)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR036961|dip:DIP-25275N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Xj7pumBXLbULLptjYCn0wOPY2zs6239 rogid:v5atHG+eoQTFFJTThcN6np307kw6239 intact-crc:BF614244C268373A|rigid:26M/tNM3n/n1M+6ozvWbmq17ufQ false sufficient binding region:490-981("MI:0442") sufficient binding region:145-297("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:G5EEH9 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-6455549|ensemblmetazoa:ZK328.5b.1|uniprotkb:D1MN48|uniprotkb:H2L014 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:nup98_caeel(display_long)|uniprotkb:ZK328.5(orf name)|uniprotkb:npp-10(gene name)|psi-mi:npp-10(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455619|imex:IM-11985-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) ensemblmetazoa:WBGene00003796(gene)|ensemblmetazoa:ZK328.5b.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030719"(P granule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043186"(P granule)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|refseq:NP_001254934.1|refseq:NP_498309.3|refseq:NP_498310.3|wormbase:ZK328.5a|wormbase:ZK328.5b|wormbase:ZK328.5c|interpro:IPR036903|interpro:IPR037665|reactome:R-CEL-9615933|interpro:IPR037637 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:Xj7pumBXLbULLptjYCn0wOPY2zs6239 intact-crc:D7BA4EF12FB3E109|rigid:ZhPS9uqsWe9rsz1kRpq8OR70RT8 false sufficient binding region:207-403("MI:0442") sufficient binding region:490-981("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2003647 intact:EBI-2003647 - - psi-mi:o44487_caeel(display_short)|psi-mi:EBI-2003647(display_long)|uniprotkb:F42A6.6(orf name) psi-mi:o44487_caeel(display_short)|psi-mi:EBI-2003647(display_long)|uniprotkb:F42A6.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455723|imex:IM-11985-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O44487(uniprot-removed-ac) uniprotkb:O44487(uniprot-removed-ac) psi-mi:"MI:0469"(intact) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:z8Q+9aSJhEoo7St1cCL6j/FVcto6239 rogid:z8Q+9aSJhEoo7St1cCL6j/FVcto6239 intact-crc:8675759C063D6B63|rigid:EQnfwSAYubMBlU03p9KjPqLXCxk false sufficient binding region:1-146("MI:0442") sufficient binding region:1-146("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34331 uniprotkb:O44548 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 intact:EBI-2002279|ensemblmetazoa:K06A5.4.1 psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:knl2_caeel(display_long)|uniprotkb:knl-2(gene name)|psi-mi:knl-2(display_short)|uniprotkb:K06A5.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455710|imex:IM-11985-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N interpro:IPR015216(SANT associated)|refseq:NP_491858.1|wormbase:K06A5.4|interpro:IPR044895|rcsb pdb:2M3A|interpro:IPR039110|ensemblmetazoa:K06A5.4.1(transcript)|ensemblmetazoa:WBGene00019432(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 rogid:75DxENUtFsHh+zV4+If5DTMKOjI6239 intact-crc:30A22BCAE7D1F34D|rigid:WfUd7IiwEZAaybOtq461epBNafY false sufficient binding region:302-649("MI:0442") sufficient binding region:1-876("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76371 uniprotkb:O17071 intact:EBI-317201|ensemblmetazoa:F56H1.4.1 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 psi-mi:prs6a_caeel(display_long)|uniprotkb:rpt-5(gene name)|psi-mi:rpt-5(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 5(gene name synonym)|uniprotkb:F56H1.4(orf name) psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455697|imex:IM-11985-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_491672.1|wormbase:F56H1.4|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F56H1.4.1(transcript)|ensemblmetazoa:WBGene00004505(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-CEL-5632684|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|interpro:IPR035254 refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:JW4UPtYlusTCwjDWZOAyH30g+Sw6239 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 intact-crc:FACB61DCFD26965B|rigid:qPrgZCPwA9r+67qFvKwR+XdC2pQ false sufficient binding region:10-101("MI:0442") sufficient binding region:9-406("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEH9 uniprotkb:P90900 intact:EBI-6455549|ensemblmetazoa:ZK328.5b.1|uniprotkb:D1MN48|uniprotkb:H2L014 intact:EBI-322249|uniprotkb:Q9GYN4|ensemblmetazoa:K05B2.3.1 psi-mi:nup98_caeel(display_long)|uniprotkb:ZK328.5(orf name)|uniprotkb:npp-10(gene name)|psi-mi:npp-10(display_short) psi-mi:ifa4_caeel(display_long)|uniprotkb:ifa-4(gene name)|psi-mi:ifa-4(display_short)|uniprotkb:K05B2.3(orf name)|uniprotkb:Intermediate filament protein A4(gene name synonym)|uniprotkb:Cel IF A4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455684|imex:IM-11985-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003796(gene)|ensemblmetazoa:ZK328.5b.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030719"(P granule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043186"(P granule)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:1990893"(mitotic chromosome centromere condensation)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR025574|refseq:NP_001254934.1|refseq:NP_498309.3|refseq:NP_498310.3|wormbase:ZK328.5a|wormbase:ZK328.5b|wormbase:ZK328.5c|interpro:IPR036903|interpro:IPR037665|reactome:R-CEL-9615933|interpro:IPR037637 refseq:NP_508836.5|wormbase:K05B2.3|reactome:R-CEL-4419969|ensemblmetazoa:K05B2.3.1(transcript)|ensemblmetazoa:WBGene00002052(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|dip:DIP-24430N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Xj7pumBXLbULLptjYCn0wOPY2zs6239 rogid:WJwjqzr8cRtjh89itzktrj4T/0o6239 intact-crc:1C5683718AFE6E07|rigid:ZHj2Nak8ii2i0QY92HlNWJ354uI false sufficient binding region:490-981("MI:0442") sufficient binding region:107-575("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17071 uniprotkb:O17071 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455671|imex:IM-11985-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 intact-crc:6B3838B1D031204C|rigid:uvcVIg3emySV9m6Yp8iS+TgtHpI false sufficient binding region:9-406("MI:0442") sufficient binding region:11-406("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:O17071 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455736|imex:IM-11985-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 intact-crc:89FCA283E2F830C1|rigid:CPU0As1IfgvC2MGa2FRv8ecCU/U false - sufficient binding region:9-406("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44761 uniprotkb:Q19969 intact:EBI-2005221|ensemblmetazoa:T12F5.1.1 intact:EBI-317340|uniprotkb:O44925|ensemblmetazoa:F32E10.4.1 psi-mi:o44761_caeel(display_long)|uniprotkb:sld-2(gene name)|psi-mi:sld-2(display_short)|uniprotkb:CELE_T12F5.1(orf name)|uniprotkb:T12F5.1(orf name) psi-mi:ima3_caeel(display_long)|uniprotkb:ima-3(gene name)|psi-mi:ima-3(display_short)|uniprotkb:F32E10.4(orf name)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455796|imex:IM-11985-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491210.1|wormbase:T12F5.1|ensemblmetazoa:T12F5.1.1(transcript)|ensemblmetazoa:WBGene00020466(gene) refseq:NP_501227.1|wormbase:F32E10.4|ensemblmetazoa:F32E10.4.1(transcript)|ensemblmetazoa:WBGene00002074(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007127"(meiosis I)|go:"GO:0007276"(gamete generation)|go:"GO:0007292"(female gamete generation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|dip:DIP-26417N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aGo4EtKYh8jY3ceq8kjre/Kwqws6239 rogid:WT7vezZFUUJSBWKoQXOmUoUD+xc6239 intact-crc:93BC2C1A556196ED|rigid:Bd4WKTH3Cky6SWSs1apb61+kC7k false - sufficient binding region:96-445("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19969 uniprotkb:Q09599 intact:EBI-317340|uniprotkb:O44925|ensemblmetazoa:F32E10.4.1 intact:EBI-2004725|ensemblmetazoa:R06F6.1.1 psi-mi:ima3_caeel(display_long)|uniprotkb:ima-3(gene name)|psi-mi:ima-3(display_short)|uniprotkb:F32E10.4(orf name)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym) psi-mi:slbp_caeel(display_long)|uniprotkb:cdl-1(gene name)|psi-mi:cdl-1(display_short)|uniprotkb:Histone stem-loop-binding protein(gene name synonym)|uniprotkb:R06F6.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455786|imex:IM-11985-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501227.1|wormbase:F32E10.4|ensemblmetazoa:F32E10.4.1(transcript)|ensemblmetazoa:WBGene00002074(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007127"(meiosis I)|go:"GO:0007276"(gamete generation)|go:"GO:0007292"(female gamete generation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|dip:DIP-26417N wormbase:R06F6.1|interpro:IPR026502|reactome:R-CEL-77588|interpro:IPR029344|interpro:IPR038294|reactome:R-CEL-73856|refseq:NP_496320.4|ensemblmetazoa:R06F6.1.1(transcript)|ensemblmetazoa:WBGene00000411(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0006915"(apoptotic process)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0051028"(mRNA transport)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WT7vezZFUUJSBWKoQXOmUoUD+xc6239 rogid:2Y2MhtayRwOZm+MaK6fQEHIkzuw6239 intact-crc:E7F304C8C950278D|rigid:QS2ueAfF9pDxXfBaa42gt4KXs94 false sufficient binding region:96-445("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22799 uniprotkb:Q7K714 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 intact:EBI-2005487|ensemblmetazoa:Y38E10A.6b.1 psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:q7k714_caeel(display_long)|uniprotkb:CELE_Y38E10A.6(orf name)|uniprotkb:ceh-100(gene name)|psi-mi:ceh-100(display_short)|uniprotkb:Y38E10A.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455746|imex:IM-11985-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 refseq:NP_001022429.1|wormbase:Y38E10A.6b|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|ensemblmetazoa:WBGene00012584(gene)|ensemblmetazoa:Y38E10A.6b.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0030182"(neuron differentiation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 rogid:ZX9oR2ALyKk1dlhwQyyMwDDQOiY6239 intact-crc:13443C0FEFAC53D3|rigid:n3QkVl7Hounl+KlnBWAN6cNzaYQ false - sufficient binding region:997-1345("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91155 uniprotkb:Q19969 intact:EBI-2002784|ensemblmetazoa:C43E11.10.1 intact:EBI-317340|uniprotkb:O44925|ensemblmetazoa:F32E10.4.1 psi-mi:p91155_caeel(display_long)|uniprotkb:cdc-6(gene name)|psi-mi:cdc-6(display_short)|uniprotkb:CELE_C43E11.10(orf name)|uniprotkb:C43E11.10(orf name) psi-mi:ima3_caeel(display_long)|uniprotkb:ima-3(gene name)|psi-mi:ima-3(display_short)|uniprotkb:F32E10.4(orf name)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455776|imex:IM-11985-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491343.1|wormbase:C43E11.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR003959(AAA ATPase, core)|reactome:R-CEL-68689|reactome:R-CEL-69017|reactome:R-CEL-68949|interpro:IPR027417|reactome:R-CEL-176187|reactome:R-CEL-68962|ensemblmetazoa:C43E11.10.1(transcript)|ensemblmetazoa:WBGene00000382(gene)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division) refseq:NP_501227.1|wormbase:F32E10.4|ensemblmetazoa:F32E10.4.1(transcript)|ensemblmetazoa:WBGene00002074(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007127"(meiosis I)|go:"GO:0007276"(gamete generation)|go:"GO:0007292"(female gamete generation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|dip:DIP-26417N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PJ1dp4bmOSuhEyJm5Kq2fT80MIY6239 rogid:WT7vezZFUUJSBWKoQXOmUoUD+xc6239 intact-crc:5B58EE4D6328A14F|rigid:MMiPtMj63DeHsF5At6oce49Gt6k false - sufficient binding region:96-445("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:Q9BKT9 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-2005827|ensemblmetazoa:Y37E3.15a.1 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:q9bkt9_caeel(display_long)|uniprotkb:npp-13(gene name)|psi-mi:npp-13(display_short)|uniprotkb:CELE_Y37E3.15(orf name)|uniprotkb:Y37E3.15(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455766|imex:IM-11985-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) interpro:IPR007231(Nucleoporin interacting component)|refseq:NP_740802.1|wormbase:Y37E3.15a|ensemblmetazoa:WBGene00003799(gene)|ensemblmetazoa:Y37E3.15a.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1903379"(regulation of mitotic chromosome condensation)|go:"GO:1990893"(mitotic chromosome centromere condensation) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:KQxxaQPFCk9tycEeORD/MJg0krY6239 intact-crc:52EC188566B5FFE4|rigid:7MMNbpGZ6Ty6MmGFRKsH9tAHOKc false - sufficient binding region:97-392("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A7LPI4 uniprotkb:O02482 intact:EBI-6455851|ensemblmetazoa:F27D4.2b.1 intact:EBI-314716|uniprotkb:P91912|ensemblmetazoa:W02D3.9.1|ensemblmetazoa:W02D3.9.2 psi-mi:a7lpi4_caeel(display_long)|uniprotkb:F27D4.2(orf name)|uniprotkb:lsy-22(gene name)|psi-mi:lsy-22(display_short)|uniprotkb:CELE_F27D4.2(orf name) psi-mi:unc37_caeel(display_long)|uniprotkb:unc-37(gene name)|psi-mi:unc-37(display_short)|uniprotkb:esg(gene name synonym)|uniprotkb:W02D3.9(orf name)|uniprotkb:Uncoordinated protein 37(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455856|imex:IM-11985-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F27D4.2b.1(transcript)|ensemblmetazoa:WBGene00009188(gene)|go:"GO:0140297"(DNA-binding transcription factor binding)|refseq:NP_492147.2|wormbase:F27D4.2b reactome:R-CEL-4641265|refseq:NP_491932.1|wormbase:W02D3.9|reactome:R-CEL-3769402|ensemblmetazoa:W02D3.9.1(transcript)|ensemblmetazoa:W02D3.9.2(transcript)|ensemblmetazoa:WBGene00006773(gene)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008134"(transcription factor binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|dip:DIP-27333N|reactome:R-CEL-201722 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:T7mx7EfdGNPcYYcIHC9TZfhSnpI6239 rogid:+e4X3QH+GChhuO2oAhaNGVwnO/o6239 intact-crc:7C57CC5939C3FC7E|rigid:FFMFxBHEpz4X+TREnP7PoO8y4+I false sufficient binding region:9-291("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XU12 uniprotkb:Q8TA83 intact:EBI-325126|ensemblmetazoa:K11D9.1a.1 intact:EBI-331999|uniprotkb:P34408|uniprotkb:Q95QJ6|ensemblmetazoa:F22B7.5a.1 psi-mi:q9xu12_caeel(display_long)|uniprotkb:klp-7(gene name)|psi-mi:klp-7(display_short)|uniprotkb:CELE_K11D9.1(orf name)|uniprotkb:K11D9.1(orf name) psi-mi:dnj10_caeel(display_long)|uniprotkb:F22B7.5(orf name)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455841|imex:IM-11985-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022677.1|wormbase:K11D9.1a|ensemblmetazoa:K11D9.1a.1(transcript)|ensemblmetazoa:WBGene00002219(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010938"(cytoplasmic microtubule depolymerization)|go:"GO:0018991"(oviposition)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|dip:DIP-26934N|reactome:R-CEL-983189 refseq:NP_498901.1|refseq:NP_498902.1|wormbase:F22B7.5a|wormbase:F22B7.5b|dip:DIP-24664N|ensemblmetazoa:F22B7.5a.1(transcript)|ensemblmetazoa:WBGene00001028(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009408"(response to heat)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CHfEKYlTwlJs6zeaXZrs0KLrlSI6239 rogid:rZSB2nN04hE44ryl282RwGo9QqQ6239 intact-crc:C113172ED5E5F946|rigid:uqTz1CYzAp/xsOVOe+La2RaaCbA false - sufficient binding region:95-294("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEM5 uniprotkb:Q22137 intact:EBI-320102|ensemblmetazoa:F22B5.7.1 intact:EBI-896209|ensemblmetazoa:T04A8.7a.1 psi-mi:zyg9_caeel(display_long)|uniprotkb:zyg-9(gene name)|psi-mi:zyg-9(display_short)|uniprotkb:F22B5.7(orf name) psi-mi:q22137_caeel(display_long)|uniprotkb:T04A8.7(orf name)|uniprotkb:CELE_T04A8.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455816|imex:IM-11985-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:NP_495784.1|uniprotkb:O61442(uniprot-removed-ac)|rcsb pdb:2OF3|wormbase:F22B5.7|ensemblmetazoa:WBGene00006994(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051231"(spindle elongation)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:F22B5.7.1(transcript)|interpro:IPR034085|interpro:IPR029632 refseq:NP_497961.1|wormbase:T04A8.7a|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR037439|reactome:R-CEL-3322077|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|ensemblmetazoa:T04A8.7a.1(transcript)|ensemblmetazoa:WBGene00011409(gene)|go:"GO:0003844"(1,4-alpha-glucan branching enzyme activity)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0043169"(cation binding)|go:"GO:0102752"("1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)") psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:d5IkZ+B1AcKT1ZE2uWfbBzd9p5U6239 rogid:ZZY5kRKZqp6pXWB0i9HcFZUpI3w6239 intact-crc:B9C984C6701E4519|rigid:zuLEZfrZ+hKBZ4BWlr1pwG8MSag false sufficient binding region:957-1415("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17607 uniprotkb:P46561 intact:EBI-316213|ensemblmetazoa:C27H6.2.1 intact:EBI-316294|ensemblmetazoa:C34E10.6.1|ensemblmetazoa:C34E10.6.2|ensemblmetazoa:C34E10.6.3 psi-mi:ruvb1_caeel(display_long)|uniprotkb:ruvb-1(gene name)|psi-mi:ruvb-1(display_short)|uniprotkb:Pontin(gene name synonym)|uniprotkb:C27H6.2(orf name) psi-mi:atpb_caeel(display_long)|uniprotkb:atp-2(gene name)|psi-mi:atp-2(display_short)|uniprotkb:C34E10.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455806|imex:IM-11985-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505567.2|reactome:R-CEL-5689880|wormbase:C27H6.2|ensemblmetazoa:C27H6.2.1(transcript)|ensemblmetazoa:WBGene00007784(gene)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0002119"(nematode larval development)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|dip:DIP-25966N reactome:R-CEL-1268020|refseq:NP_498111.2|wormbase:C34E10.6|ensemblmetazoa:C34E10.6.1(transcript)|ensemblmetazoa:C34E10.6.2(transcript)|ensemblmetazoa:C34E10.6.3(transcript)|ensemblmetazoa:WBGene00000229(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005929"(cilium)|go:"GO:0007617"(mating behavior)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030421"(defecation)|go:"GO:0040024"(dauer larval development)|go:"GO:0040039"(inductive cell migration)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0097730"(non-motile cilium)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|dip:DIP-24363N|reactome:R-CEL-163210|reactome:R-CEL-8949613 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ClLKmYAiHB+gCDwvg9vaeL2MIxc6239 rogid:7NyQvjFV+TNx6et/+gylNZki55U6239 intact-crc:4A92FAF612776876|rigid:Ea6/yPH1a9f7dsi5jY2Piiobfyo false sufficient binding region:96-348("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39745-1 uniprotkb:Q8TA83 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 intact:EBI-331999|uniprotkb:P34408|uniprotkb:Q95QJ6|ensemblmetazoa:F22B7.5a.1 psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:dnj10_caeel(display_long)|uniprotkb:F22B7.5(orf name)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455826|imex:IM-11985-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) refseq:NP_498901.1|refseq:NP_498902.1|wormbase:F22B7.5a|wormbase:F22B7.5b|dip:DIP-24664N|ensemblmetazoa:F22B7.5a.1(transcript)|ensemblmetazoa:WBGene00001028(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009408"(response to heat)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 rogid:rZSB2nN04hE44ryl282RwGo9QqQ6239 intact-crc:D84390D4A2BC9B4F|rigid:81PRdkoKBj088o0twLMlGP2zLT8 false - sufficient binding region:95-352("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XQ8 uniprotkb:P34647-1 intact:EBI-2006682|ensemblmetazoa:Y39G10AR.14a.1|ensemblmetazoa:Y39G10AR.14a.2 intact:EBI-6455889|ensemblmetazoa:ZK632.1a.1 psi-mi:mcm4_caeel(display_long)|uniprotkb:mcm-4(gene name)|psi-mi:mcm-4(display_short)|uniprotkb:let-358(gene name synonym)|uniprotkb:lin-6(gene name synonym)|uniprotkb:Y39G10AR.14(orf name) psi-mi:p34647-1(display_long)|uniprotkb:ZK632.1(orf name)|uniprotkb:mcm-6(gene name)|psi-mi:mcm-6(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455886|imex:IM-11985-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y39G10AR.14a|interpro:IPR033762|reactome:R-CEL-69052|refseq:NP_490962.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-CEL-176187|interpro:IPR027417|interpro:IPR027925|interpro:IPR041562|reactome:R-CEL-68962|reactome:R-CEL-68949|ensemblmetazoa:WBGene00003156(gene)|ensemblmetazoa:Y39G10AR.14a.1(transcript)|ensemblmetazoa:Y39G10AR.14a.2(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007399"(nervous system development)|go:"GO:0008406"(gonad development)|go:"GO:0040011"(locomotion)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation) intact:EBI-2006759(isoform-parent)|ensemblmetazoa:WBGene00003158(gene)|ensemblmetazoa:ZK632.1a.1(transcript) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s3LjC/8JGa0CG7Agp7POMk9kBsA6239 rogid:Bv0Zazm8QYFQ5nW05WKMSnLzHVs6239 intact-crc:EB36155F795E9FF9|rigid:uKeNVX4NZRcUUDjzCgKJVwBDN8E false sufficient binding region:91-823("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22799 uniprotkb:C6KRN1 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 intact:EBI-323135|intact:EBI-2007498|uniprotkb:C6KRN2|uniprotkb:Q1ZXT3|uniprotkb:Q1ZXT4|ensemblmetazoa:R10D12.14c.1 psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:sao1_caeel(display_long)|uniprotkb:sao-1(gene name)|psi-mi:sao-1(display_short)|uniprotkb:R10D12.14(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455876|imex:IM-11985-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 interpro:IPR003169(GYF)|wormbase:R10D12.14c|refseq:NP_001041150.1|refseq:NP_001041151.1|refseq:NP_001256551.1|refseq:NP_001256550.1|wormbase:R10D12.14a|wormbase:R10D12.14b|wormbase:R10D12.14d|ensemblmetazoa:R10D12.14c.1(transcript)|ensemblmetazoa:WBGene00011195(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0032154"(cleavage furrow)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0060625"(regulation of protein deneddylation)|go:"GO:0071987"(WD40-repeat domain binding)|interpro:IPR035445 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 rogid:ltki1LgPEwUkjZhPQy0PvwRbBqc6239 intact-crc:0FE00780E2D2A76A|rigid:BZyCDbzN9eCRXPRtM9uNVg7J9i0 false - sufficient binding region:92-245("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21484 uniprotkb:P90916 intact:EBI-324321|ensemblmetazoa:M03C11.4.1 intact:EBI-324314|uniprotkb:A2JDY3|uniprotkb:O62411|ensemblmetazoa:K07A1.12.1 psi-mi:q21484_caeel(display_long)|uniprotkb:hat-1(gene name)|psi-mi:hat-1(display_short)|uniprotkb:M03C11.4(orf name)|uniprotkb:CELE_M03C11.4(orf name) psi-mi:lin53_caeel(display_long)|uniprotkb:lin-53(gene name)|psi-mi:lin-53(display_short)|uniprotkb:rba-2(gene name synonym)|uniprotkb:K07A1.12(orf name)|uniprotkb:Abnormal cell lineage protein 53(gene name synonym)|uniprotkb:Synthetic multivulva protein p48(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455866|imex:IM-11985-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019467|wormbase:M03C11.4|refseq:NP_499296.2|ensemblmetazoa:M03C11.4.1(transcript)|ensemblmetazoa:WBGene00044069(gene)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006348"|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|reactome:R-CEL-3214847|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR037113 refseq:NP_492552.1|wormbase:K07A1.12|reactome:R-CEL-2559580|reactome:R-CEL-3214858|ensemblmetazoa:K07A1.12.1(transcript)|ensemblmetazoa:WBGene00003036(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0070176"(DRM complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|reactome:R-CEL-3214847|dip:DIP-24440N|reactome:R-CEL-8951664|reactome:R-CEL-8943724|reactome:R-CEL-1538133|reactome:R-CEL-212300|reactome:R-CEL-3214815|reactome:R-CEL-8953750 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ItS0fmU+AsVKP9gIEM4Ag/isWe86239 rogid:v5/7m30zbtMyaxt8xomuotdJqcA6239 intact-crc:8E33E8C0B1B18114|rigid:s0lA8BKPELvV1XoJixrDkC47VK8 false sufficient binding region:92-411("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17666 uniprotkb:Q10958 intact:EBI-317257|ensemblmetazoa:C45G3.1.1 intact:EBI-6455901|ensemblmetazoa:B0353.1a.1 psi-mi:o17666_caeel(display_long)|uniprotkb:aspm-1(gene name)|psi-mi:aspm-1(display_short)|uniprotkb:C45G3.1(orf name)|uniprotkb:CELE_C45G3.1(orf name) psi-mi:yt31_caeel(display_long)|uniprotkb:B0353.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455905|imex:IM-11985-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492467.1|wormbase:C45G3.1|ensemblmetazoa:C45G3.1.1(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|ensemblmetazoa:WBGene00008107(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0051233"(spindle midzone)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051296"(establishment of meiotic spindle orientation)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|dip:DIP-24587N ensemblmetazoa:B0353.1a.1(transcript)|ensemblmetazoa:WBGene00015155(gene)|refseq:NP_497210.1|wormbase:B0353.1a psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:3HsZ5W1fxEraEGP5zR4dmX+8mo06239 rogid:VCgUbqnsBVsBTT1q7xZcvyXVk1Y6239 intact-crc:A6F2E07FDCA5B99B|rigid:cEZU4eEk7HftAm9cQXsRcpxTCuQ false - sufficient binding region:9-182("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17763 uniprotkb:H9G2T2 intact:EBI-315760|ensemblmetazoa:C06H2.1.1|ensemblmetazoa:C06H2.1.2 intact:EBI-6455925|ensemblmetazoa:M7.2b.1 psi-mi:q17763_caeel(display_long)|uniprotkb:atp-5(gene name)|psi-mi:atp-5(display_short)|uniprotkb:CELE_C06H2.1(orf name)|uniprotkb:C06H2.1(orf name) psi-mi:h9g2t2_caeel(display_long)|uniprotkb:CELE_M7.2(orf name)|uniprotkb:M7.2(orf name)|uniprotkb:klc-1(gene name)|psi-mi:klc-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455930|imex:IM-11985-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505829.1|wormbase:C06H2.1|ensemblmetazoa:C06H2.1.1(transcript)|ensemblmetazoa:C06H2.1.2(transcript)|ensemblmetazoa:WBGene00007385(gene)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|dip:DIP-24522N|reactome:R-CEL-163210|reactome:R-CEL-8949613 ensemblmetazoa:M7.2b.1(transcript)|ensemblmetazoa:WBGene00002214(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051295"(establishment of meiotic spindle localization)|wormbase:M7.2b|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:NP_001255534.1|reactome:R-CEL-983189 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+vSu1uRwJQcgMcmm0VNIfvW1Qek6239 rogid:DMS9bskwnjjUomNOe0vwmmcpXDc6239 intact-crc:A14A98EC3745EA8A|rigid:a2CRUgsK53y+kaiJB8npONr9Aes false - sufficient binding region:89-536("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02108 uniprotkb:A0A0S4XR43 intact:EBI-329675|ensemblmetazoa:W08F4.8a.1 intact:EBI-313448|ensemblmetazoa:Y37A1B.1a.1 psi-mi:cdc37_caeel(display_long)|uniprotkb:W08F4.8(orf name)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division cycle-related protein 37(gene name synonym)|uniprotkb:cdc-37(gene name)|psi-mi:cdc-37(display_short) psi-mi:a0a0s4xr43_caeel(display_long)|uniprotkb:Y37A1B.1(orf name)|uniprotkb:ccar-1(gene name)|psi-mi:ccar-1(display_short)|uniprotkb:CELE_Y37A1B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455940|imex:IM-11985-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001040820.1|wormbase:W08F4.8a|reactome:R-CEL-114608|dip:DIP-25193N|ensemblmetazoa:W08F4.8a.1(transcript)|ensemblmetazoa:WBGene00021097(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-CEL-8863795|reactome:R-CEL-9652282|reactome:R-CEL-5675482 interpro:IPR003034(DNA-binding SAP)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|refseq:NP_001305185.1|uniprotkb:G5EFJ2(uniprot-removed-ac)|ensemblmetazoa:WBGene00003085(gene)|ensemblmetazoa:Y37A1B.1a.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|wormbase:Y37A1B.1a|reactome:R-CEL-3371453|reactome:R-CEL-72163|interpro:IPR036361 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BGPUAjBwpp1jT1o4miWT7nTRwus6239 rogid:bN9ZgS0BenMNvi68x3PvK6Gw++E6239 intact-crc:6D191E334C2D4F72|rigid:1rd4ABNq/1Hr3W/FxNdCNO0MdI8 false - sufficient binding region:888-1215("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:Q20151 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-2006034|ensemblmetazoa:F38B7.3.1 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q20151_caeel(display_long)|uniprotkb:CELE_F38B7.3(orf name)|uniprotkb:F38B7.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455950|imex:IM-11985-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 refseq:NP_505929.1|wormbase:F38B7.3|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR039680|ensemblmetazoa:F38B7.3.1(transcript)|ensemblmetazoa:WBGene00009534(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045595"(regulation of cell differentiation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:3b2cVuLqSwXLt28jIMQJ9AeONkg6239 intact-crc:949E294070138E33|rigid:ynLyisS1M8biv+RjiozSkTyii+Q false - sufficient binding region:88-407("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20058 uniprotkb:Q18787 intact:EBI-318041|ensemblmetazoa:F35G12.12.1 intact:EBI-318033|ensemblmetazoa:C52E4.4.2|ensemblmetazoa:C52E4.4.1 psi-mi:q20058_caeel(display_long)|uniprotkb:F35G12.12(orf name)|uniprotkb:CELE_F35G12.12(orf name) psi-mi:prs7_caeel(display_long)|uniprotkb:C52E4.4(orf name)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:rpt-1(gene name)|psi-mi:rpt-1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455960|imex:IM-11985-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019538|refseq:NP_497932.2|wormbase:F35G12.12|ensemblmetazoa:F35G12.12.1(transcript)|ensemblmetazoa:WBGene00009445(gene)|go:"GO:0043248"(proteasome assembly)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 refseq:NP_506005.1|wormbase:C52E4.4|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|ensemblmetazoa:C52E4.4.1(transcript)|ensemblmetazoa:C52E4.4.2(transcript)|ensemblmetazoa:WBGene00004501(gene)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-CEL-5632684|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-6798695|reactome:R-CEL-68949|interpro:IPR035245|reactome:R-CEL-8932339|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WCTvWv//evJ5II2p5fBEhrbvKtA6239 rogid:9wPZ9U2T4K2dhy20UIXh0yUfbEc6239 intact-crc:FF309159098C4556|rigid:5+v7rzdk4ypTVHtPPirmZm7Q23E false sufficient binding region:85-491("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09248 uniprotkb:Q09248 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455915|imex:IM-11985-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 intact-crc:11485E46742DC4E6|rigid:x2nJf6q/6L5a+DB+dAqhSb6Ox8g false - sufficient binding region:91-227("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:O45599 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-319105|ensemblmetazoa:H02I12.1.1 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:cbd1_caeel(display_long)|uniprotkb:cbd-1(gene name)|psi-mi:cbd-1(display_short)|uniprotkb:H02I12.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455990|imex:IM-11985-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) refseq:NP_502145.2|wormbase:H02I12.1|ensemblmetazoa:H02I12.1.1(transcript)|ensemblmetazoa:WBGene00010351(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|go:"GO:0030703"(eggshell formation)|go:"GO:0071944"(cell periphery)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|dip:DIP-26633N psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:D0mH3+/FTIlBGARvBXqMOF4FHbE6239 intact-crc:E8A1F1EEE445E441|rigid:6CmGAHxmUXl3CZSoZ16JYhQ4pE0 false - sufficient binding region:831-1319("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:Q19286 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-320062|uniprotkb:Q21064|uniprotkb:Q95QM2|ensemblmetazoa:F10C1.7a.1 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:ifb2_caeel(display_long)|uniprotkb:ifb-2(gene name)|psi-mi:ifb-2(display_short)|uniprotkb:F10C1.7(orf name)|uniprotkb:Intermediate filament protein B2(gene name synonym)|uniprotkb:Cel IF B2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455980|imex:IM-11985-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) refseq:NP_495133.1|refseq:NP_495134.1|wormbase:F10C1.7a|wormbase:F10C1.7c|ensemblmetazoa:F10C1.7a.1(transcript)|ensemblmetazoa:WBGene00002054(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0030054"(cell junction)|go:"GO:0045179"(apical cortex)|go:"GO:1990357"(terminal web)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-26763N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:SIkUfQ59iJC29JoQFWYxCZdKiv86239 intact-crc:B2BF2AEC57DA745A|rigid:x3frmYxzYRSm/A7ZuvMisZxGzV0 false - sufficient binding region:83-543("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18262 uniprotkb:G5EDD8 intact:EBI-2002466|ensemblmetazoa:C27F2.7.1 intact:EBI-314583|ensemblmetazoa:F46A9.4.1 psi-mi:ypi7_caeel(display_long)|uniprotkb:C27F2.7(orf name) psi-mi:g5edd8_caeel(display_long)|uniprotkb:skr-2(gene name)|psi-mi:skr-2(display_short)|uniprotkb:CELE_F46A9.4(orf name)|uniprotkb:F46A9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456000|imex:IM-11985-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498056.2|wormbase:C27F2.7|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|ensemblmetazoa:C27F2.7.1(transcript)|ensemblmetazoa:WBGene00016169(gene) uniprotkb:Q93731(uniprot-removed-ac)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492512.1|wormbase:F46A9.4|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0097602"(cullin family protein binding)|ensemblmetazoa:F46A9.4.1(transcript)|ensemblmetazoa:WBGene00004808(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|interpro:IPR036296 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BGB1Hx3Vk0nwHjWeZ39beSwbCtQ6239 rogid:j2g9jI5SVR7+s5r1E3Pk+j/4lgo6239 intact-crc:B8BD6EB9A210AD01|rigid:UpBfhwol8ny1selMCApbp4su86k false sufficient binding region:82-185("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEM5 uniprotkb:Q09544 intact:EBI-320102|ensemblmetazoa:F22B5.7.1 intact:EBI-313923|ensemblmetazoa:F58F12.1.1 psi-mi:zyg9_caeel(display_long)|uniprotkb:zyg-9(gene name)|psi-mi:zyg-9(display_short)|uniprotkb:F22B5.7(orf name) psi-mi:atpd_caeel(display_long)|uniprotkb:F58F12.1(orf name)|uniprotkb:F-ATPase delta subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6455970|imex:IM-11985-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:NP_495784.1|uniprotkb:O61442(uniprot-removed-ac)|rcsb pdb:2OF3|wormbase:F22B5.7|ensemblmetazoa:WBGene00006994(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051231"(spindle elongation)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:F22B5.7.1(transcript)|interpro:IPR034085|interpro:IPR029632 refseq:NP_495286.1|wormbase:F58F12.1|ensemblmetazoa:F58F12.1.1(transcript)|ensemblmetazoa:WBGene00019061(gene)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|dip:DIP-27343N|reactome:R-CEL-163210|reactome:R-CEL-8949613 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:d5IkZ+B1AcKT1ZE2uWfbBzd9p5U6239 rogid:gHgBzMIAudIXQ3KuHjnnm6T4VRQ6239 intact-crc:5DBC8C2A8BE1A3D1|rigid:/wYwyY6J+x0IZ8tT+/VIPagJv9Q false sufficient binding region:841-1326("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22469 uniprotkb:G5ECL3 intact:EBI-329638|ensemblmetazoa:T13H5.4.1 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 psi-mi:q22469_caeel(display_long)|uniprotkb:T13H5.4(orf name)|uniprotkb:CELE_T13H5.4(orf name) psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456050|imex:IM-11985-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495799.1|wormbase:T13H5.4|reactome:R-CEL-72163|dip:DIP-25197N|ensemblmetazoa:T13H5.4.1(transcript)|ensemblmetazoa:WBGene00011758(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776 interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:GLuSG37nqmw6DTs2aINb+mMiwi06239 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 intact-crc:B8437F50A1B21DD3|rigid:0g1a+pB2+8Eb6fGrngE3qKHSJxY false sufficient binding region:80-148("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECU1 uniprotkb:G5EE07 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 intact:EBI-329476|ensemblmetazoa:R74.3b.1 psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:g5ee07_caeel(display_long)|uniprotkb:xbp-1(gene name)|psi-mi:xbp-1(display_short)|uniprotkb:R74.3(orf name)|uniprotkb:CELE_R74.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456040|imex:IM-11985-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 uniprotkb:Q8WRF1(uniprot-removed-ac)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|refseq:NP_001076646.1|wormbase:R74.3|ensemblmetazoa:R74.3b.1(transcript)|ensemblmetazoa:WBGene00006959(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 rogid:TIdIllD7KrmvBVi54fMg9HXkANM6239 intact-crc:9C261A65767009BC|rigid:TZhQpLh8PhXzIUnOVa0kbCpJK5o false - sufficient binding region:80-287("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECU1 uniprotkb:Q18262 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 intact:EBI-2002466|ensemblmetazoa:C27F2.7.1 psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:ypi7_caeel(display_long)|uniprotkb:C27F2.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456010|imex:IM-11985-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 refseq:NP_498056.2|wormbase:C27F2.7|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|ensemblmetazoa:C27F2.7.1(transcript)|ensemblmetazoa:WBGene00016169(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 rogid:BGB1Hx3Vk0nwHjWeZ39beSwbCtQ6239 intact-crc:38159B3929520119|rigid:v7+8GUIDV28xNVneqYfu3TOFvDs false - sufficient binding region:82-185("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91283 uniprotkb:Q20874 intact:EBI-313421|ensemblmetazoa:F27C1.7a.1|ensemblmetazoa:F27C1.7a.2|ensemblmetazoa:F27C1.7a.3|ensemblmetazoa:F27C1.7a.4|ensemblmetazoa:F27C1.7a.5 intact:EBI-2003309|ensemblmetazoa:F56D2.2.1 psi-mi:p91283_caeel(display_long)|uniprotkb:atp-3(gene name)|psi-mi:atp-3(display_short)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)|uniprotkb:CELE_F27C1.7(orf name)|uniprotkb:F27C1.7(orf name) psi-mi:q20874_caeel(display_long)|uniprotkb:F56D2.2(orf name)|uniprotkb:CELE_F56D2.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456030|imex:IM-11985-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021420.1|wormbase:F27C1.7a|ensemblmetazoa:F27C1.7a.1(transcript)|ensemblmetazoa:F27C1.7a.2(transcript)|ensemblmetazoa:F27C1.7a.3(transcript)|ensemblmetazoa:F27C1.7a.4(transcript)|ensemblmetazoa:F27C1.7a.5(transcript)|ensemblmetazoa:WBGene00000230(gene)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR026015|dip:DIP-26184N wormbase:F56D2.2|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR031127|reactome:R-CEL-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044066|refseq:NP_498200.1|ensemblmetazoa:F56D2.2.1(transcript)|ensemblmetazoa:WBGene00018964(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2020/06/18 rogid:1NTGNlc9wMqgCOORpCDkRfohA3Y6239 rogid:DWbbWEhYD+5h5suLx/UgETSGJNI6239 intact-crc:1578AF26943B8412|rigid:kRuTBGd9Le0TcRME59SqXzppZ/I false - sufficient binding region:81-256,290-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90925 uniprotkb:O01869 intact:EBI-318020|ensemblmetazoa:K08F8.4a.1|uniprotkb:I2HA98|uniprotkb:Q9XYQ5 intact:EBI-314419|ensemblmetazoa:D1007.6.1 psi-mi:ph4h_caeel(display_long)|uniprotkb:pah-1(gene name)|psi-mi:pah-1(display_short)|uniprotkb:Phe-4-monooxygenase(gene name synonym)|uniprotkb:Biogenic amine synthesis protein 2(gene name synonym)|uniprotkb:K08F8.4(orf name)|uniprotkb:bas-2(gene name synonym)|uniprotkb:Tryptophan 5-monooxygenase(gene name synonym) psi-mi:o01869_caeel(display_long)|uniprotkb:rps-10(gene name)|psi-mi:rps-10(display_short)|uniprotkb:CELE_D1007.6(orf name)|uniprotkb:D1007.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456020|imex:IM-11985-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:K08F8.4a|refseq:NP_001254185.1|ensemblmetazoa:K08F8.4a.1(transcript)|ensemblmetazoa:WBGene00000240(gene)|go:"GO:0000003"(reproduction)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0004510"(tryptophan 5-monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006571"(tyrosine biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040002"(collagen and cuticulin-based cuticle development)|go:"GO:0042438"(melanin biosynthetic process)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR005961(Phenylalanine-4-hydroxylase, tetrameric form)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041912|dip:DIP-25264N|refseq:NP_001254184.1|wormbase:K08F8.4b|reactome:R-CEL-8964208 refseq:NP_491398.1|wormbase:D1007.6|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975957|ensemblmetazoa:D1007.6.1(transcript)|ensemblmetazoa:WBGene00004479(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR036388|interpro:IPR037447|reactome:R-CEL-72649|reactome:R-CEL-975956|dip:DIP-25833N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Ceg0vwDFmdjAryQGSjHA7yBFPXc6239 rogid:RzHFVJ8zndfWCq1k0jNIKLRQTSU6239 intact-crc:61C7FB090B713839|rigid:JkRIAnTcsVz1dAG4Z6C9vabr/PA false sufficient binding region:81-457("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76258 uniprotkb:H9G2T2 intact:EBI-2002148|ensemblmetazoa:C09G12.9.1 intact:EBI-6455925|ensemblmetazoa:M7.2b.1 psi-mi:o76258_caeel(display_long)|uniprotkb:tsg-101(gene name)|psi-mi:tsg-101(display_short)|uniprotkb:CELE_C09G12.9(orf name)|uniprotkb:C09G12.9(orf name) psi-mi:h9g2t2_caeel(display_long)|uniprotkb:CELE_M7.2(orf name)|uniprotkb:M7.2(orf name)|uniprotkb:klc-1(gene name)|psi-mi:klc-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456117|imex:IM-11985-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500364.2|wormbase:C09G12.9|interpro:IPR017916|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR008883(Tumour susceptibility gene 101)|reactome:R-CEL-917729|interpro:IPR037202|ensemblmetazoa:C09G12.9.1(transcript)|ensemblmetazoa:WBGene00015658(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process) ensemblmetazoa:M7.2b.1(transcript)|ensemblmetazoa:WBGene00002214(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051295"(establishment of meiotic spindle localization)|wormbase:M7.2b|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:NP_001255534.1|reactome:R-CEL-983189 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tAhzbKmVoJZA+IwR6RLdGgDFIYI6239 rogid:DMS9bskwnjjUomNOe0vwmmcpXDc6239 intact-crc:C7B80FB3A2FCB5C5|rigid:ACdIceD6BszZVOmV9urv371ycSs false - sufficient binding region:77-536("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22799 uniprotkb:Q19816 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 intact:EBI-328360|ensemblmetazoa:F26F4.5.1|ensemblmetazoa:F26F4.5.2 psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:q19816_caeel(display_long)|uniprotkb:F26F4.5(orf name)|uniprotkb:CELE_F26F4.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456097|imex:IM-11985-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 refseq:NP_498024.1|wormbase:F26F4.5|dip:DIP-26397N|ensemblmetazoa:F26F4.5.1(transcript)|ensemblmetazoa:F26F4.5.2(transcript)|ensemblmetazoa:WBGene00017827(gene)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 rogid:thdMKNfAzVhyZRmzrDZkLU+Jg306239 intact-crc:757B0D83698BEB31|rigid:/BxCB0U2YyxouY9l0qiQkbGyKeU false - sufficient binding region:78-465("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62011 uniprotkb:Q95XY1 intact:EBI-6456084|ensemblmetazoa:B0379.3a.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:o62011_caeel(display_long)|uniprotkb:B0379.3(orf name)|uniprotkb:mut-16(gene name)|psi-mi:mut-16(display_short)|uniprotkb:CELE_B0379.3(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456081|imex:IM-11985-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:B0379.3a.1(transcript)|ensemblmetazoa:WBGene00003508(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016246"(RNA interference)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:1990633"(mutator focus)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_492660.3|wormbase:B0379.3a refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gMuLdz+fFz3VGJe/rR1zhKWvqIQ6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:5D45D76700B122C0|rigid:5/vMcJFLOFD5lmEsIuFvtCthRxk false sufficient binding region:785-1054("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22799 uniprotkb:Q18529 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 intact:EBI-314884|ensemblmetazoa:C39D10.7.2|ensemblmetazoa:C39D10.7.1 psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:q18529_caeel(display_long)|uniprotkb:C39D10.7(orf name)|uniprotkb:CELE_C39D10.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456071|imex:IM-11985-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 refseq:NP_509334.3|wormbase:C39D10.7|ensemblmetazoa:C39D10.7.2(transcript)|ensemblmetazoa:WBGene00016534(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|ensemblmetazoa:C39D10.7.1(transcript)|dip:DIP-27006N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 rogid:gnU6jSkV05zYFXSGRFYUIcPLW5Q6239 intact-crc:FA50843616D508DF|rigid:AsouAeQv2AMr0HEhYv+HyBtJpqw false - sufficient binding region:785-1171("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 intact:EBI-6456063 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-6306478 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:ebi6306478(display_short)|psi-mi:EBI-6456063(display_long)|intact:ZK328.2x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456060|imex:IM-11985-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 - intact-crc:AB69AA77DDC48445 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17868 uniprotkb:Q18529 intact:EBI-314859|ensemblmetazoa:C09G4.3.1 intact:EBI-314884|ensemblmetazoa:C39D10.7.2|ensemblmetazoa:C39D10.7.1 psi-mi:cks1_caeel(display_long)|uniprotkb:cks-1(gene name)|psi-mi:cks-1(display_short)|uniprotkb:dom-6(gene name synonym)|uniprotkb:C09G4.3(orf name) psi-mi:q18529_caeel(display_long)|uniprotkb:C39D10.7(orf name)|uniprotkb:CELE_C39D10.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456107|imex:IM-11985-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501457.1|wormbase:C09G4.3|ensemblmetazoa:C09G4.3.1(transcript)|ensemblmetazoa:WBGene00001051(gene)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR000789(Cyclin-dependent kinase, regulatory subunit)|interpro:IPR036858|dip:DIP-25964N|reactome:R-CEL-69231|reactome:R-CEL-187577 refseq:NP_509334.3|wormbase:C39D10.7|ensemblmetazoa:C39D10.7.2(transcript)|ensemblmetazoa:WBGene00016534(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|ensemblmetazoa:C39D10.7.1(transcript)|dip:DIP-27006N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OlpJM8zMwCqm6eB6A34tlx7WkrI6239 rogid:gnU6jSkV05zYFXSGRFYUIcPLW5Q6239 intact-crc:9188D24F06C507F8|rigid:Fx1J+pFlaCrsOkRoOaCG+Xqp1r4 false - sufficient binding region:783-1171("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17902-2 uniprotkb:Q22799 intact:EBI-17158122|ensemblmetazoa:C10G6.1b.1|ensemblmetazoa:C10G6.1b.2|intact:EBI-6456175 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:q17902-2(display_long)|uniprotkb:egal-1(gene name)|psi-mi:egal-1(display_short)|uniprotkb:C10G6.1(orf name) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456172|imex:IM-11985-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C10G6.1b.1(transcript)|ensemblmetazoa:C10G6.1b.2(transcript)|ensemblmetazoa:WBGene00015680(gene)|intact:EBI-328330(isoform-parent) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2018/04/06 rogid:pFlp1GCDCzirQagZNeMD4qfr0es6239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:B9D6BF823D06C113|rigid:Bafi3XwQefNZWsGdg9ESgAlAyfE false sufficient binding region:74-569("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16658 uniprotkb:H2L0K1 intact:EBI-2002051|ensemblmetazoa:C03H5.2.1 intact:EBI-316613|ensemblmetazoa:T02C5.1b.1 psi-mi:o16658_caeel(display_long)|uniprotkb:C03H5.2(orf name)|uniprotkb:nstp-4(gene name)|psi-mi:nstp-4(display_short)|uniprotkb:CELE_C03H5.2(orf name) psi-mi:h2l0k1_caeel(display_long)|uniprotkb:T02C5.1(orf name)|uniprotkb:CELE_T02C5.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456162|imex:IM-11985-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493723.3|wormbase:C03H5.2|interpro:IPR007271(Nucleotide-sugar transporter)|reactome:R-CEL-727802|ensemblmetazoa:C03H5.2.1(transcript)|ensemblmetazoa:WBGene00015404(gene)|go:"GO:0005459"(UDP-galactose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0030173"(integral component of Golgi membrane) uniprotkb:Q7YZH3(uniprot-removed-ac)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|refseq:NP_001024870.1|wormbase:T02C5.1b|ensemblmetazoa:T02C5.1b.1(transcript)|ensemblmetazoa:WBGene00020158(gene)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Wvd85LmGaCHUGMUa+I1e01qJtpE6239 rogid:ItXNa/PIXgphtRQzSx525L9DBhM6239 intact-crc:4570B07E59775B7B|rigid:eHrgGytdEHqDumfgDhM5hTEVsaA false - sufficient binding region:75-392("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55155 uniprotkb:Q22078 intact:EBI-2004953|ensemblmetazoa:K09F5.2.1 intact:EBI-323051|ensemblmetazoa:T01G9.4.1|ensemblmetazoa:T01G9.4.2 psi-mi:vit1_caeel(display_long)|uniprotkb:K09F5.2(orf name)|uniprotkb:vit-1(gene name)|psi-mi:vit-1(display_short) psi-mi:q22078_caeel(display_long)|uniprotkb:npp-2(gene name)|psi-mi:npp-2(display_short)|uniprotkb:CELE_T01G9.4(orf name)|uniprotkb:T01G9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456152|imex:IM-11985-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509305.1|wormbase:K09F5.2|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR001846(von Willebrand factor, type D)|ensemblmetazoa:K09F5.2.1(transcript)|ensemblmetazoa:WBGene00006925(gene)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0045735"(nutrient reservoir activity) refseq:NP_492256.1|wormbase:T01G9.4|interpro:IPR011502(Nucleoporin, Nup85-like)|ensemblmetazoa:T01G9.4.1(transcript)|ensemblmetazoa:T01G9.4.2(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090435"(protein localization to nuclear envelope)|ensemblmetazoa:WBGene00003788(gene)|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:IHmsBEkoN7plsNMuJhdYmx9tHz46239 rogid:zeIaeaV7GOQHaMra/3zZ7xf75q46239 intact-crc:D1B2EF585C2AE0E5|rigid:rUKMTdm+Nd5BF7Llss0nhEE8Sz0 false sufficient binding region:767-1616("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4A7-1 uniprotkb:Q9XWR1 intact:EBI-6456140|ensemblmetazoa:Y77E11A.13a.1 intact:EBI-2002612|intact:EBI-6534487|uniprotkb:A7DTF1|uniprotkb:D3NQA3|ensemblmetazoa:Y11D7A.12a.1 psi-mi:q9n4a7-1(display_long)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:Nuclear pore complex protein 20(gene name synonym)|uniprotkb:npp-20(gene name)|psi-mi:npp-20(display_short)|uniprotkb:CeSec13R(gene name synonym)|uniprotkb:sec-13(gene name synonym)|uniprotkb:Y77E11A.13(orf name) psi-mi:flh1_caeel(display_long)|uniprotkb:flh-1(gene name)|psi-mi:flh-1(display_short)|uniprotkb:Y11D7A.12(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456137|imex:IM-11985-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318290(isoform-parent)|ensemblmetazoa:WBGene00003806(gene)|ensemblmetazoa:Y77E11A.13a.1(transcript) refseq:NP_501618.2|wormbase:Y11D7A.12a|wormbase:Y11D7A.12b|wormbase:Y11D7A.12c|dip:DIP-24849N|ensemblmetazoa:WBGene00012435(gene)|ensemblmetazoa:Y11D7A.12a.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZKmmnaa7DFkQzBBKNad56Ic7GvI6239 rogid:BUwEONwxmU5dE1HyJh2inla8obA6239 intact-crc:E11A5D6BD4BF4DCB|rigid:A3BH61iOsXdFqwJbWaqq1TGZSYo false - sufficient binding region:77-507("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWR1 uniprotkb:Q95YD5 intact:EBI-2002612|intact:EBI-6534487|uniprotkb:A7DTF1|uniprotkb:D3NQA3|ensemblmetazoa:Y11D7A.12a.1 intact:EBI-313806|ensemblmetazoa:C30F8.2.1|ensemblmetazoa:C30F8.2.2|ensemblmetazoa:C30F8.2.3 psi-mi:flh1_caeel(display_long)|uniprotkb:flh-1(gene name)|psi-mi:flh-1(display_short)|uniprotkb:Y11D7A.12(orf name) psi-mi:q95yd5_caeel(display_long)|uniprotkb:vha-16(gene name)|psi-mi:vha-16(display_short)|uniprotkb:CELE_C30F8.2(orf name)|uniprotkb:C30F8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456127|imex:IM-11985-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501618.2|wormbase:Y11D7A.12a|wormbase:Y11D7A.12b|wormbase:Y11D7A.12c|dip:DIP-24849N|ensemblmetazoa:WBGene00012435(gene)|ensemblmetazoa:Y11D7A.12a.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type) refseq:NP_491515.2|wormbase:C30F8.2|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|reactome:R-CEL-77387|reactome:R-CEL-1222556|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|ensemblmetazoa:C30F8.2.1(transcript)|ensemblmetazoa:C30F8.2.2(transcript)|ensemblmetazoa:C30F8.2.3(transcript)|ensemblmetazoa:WBGene00016258(gene)|go:"GO:0005769"(early endosome)|go:"GO:0007034"(vacuolar transport)|interpro:IPR044911|interpro:IPR035067|interpro:IPR036079|reactome:R-CEL-917977|reactome:R-CEL-983712|reactome:R-CEL-9639288 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BUwEONwxmU5dE1HyJh2inla8obA6239 rogid:1GQOWcfyhwox5dRmSUc3JdSShKM6239 intact-crc:0A4721A7A6599935|rigid:9ChpVQtY4S5A7sMh6KPDfJXUwZY false sufficient binding region:77-507("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39745-1 uniprotkb:Q23463 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 intact:EBI-2002136|ensemblmetazoa:ZK328.2.1|ensemblmetazoa:ZK328.2.2 psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:q23463_caeel(display_long)|uniprotkb:eftu-2(gene name)|psi-mi:eftu-2(display_short)|uniprotkb:CELE_ZK328.2(orf name)|uniprotkb:ZK328.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456227|imex:IM-11985-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) refseq:NP_498308.1|wormbase:ZK328.2|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|reactome:R-CEL-72163|reactome:R-CEL-72165|interpro:IPR035647|interpro:IPR035655|interpro:IPR031950|interpro:IPR027417|interpro:IPR044121|ensemblmetazoa:WBGene00001166(gene)|ensemblmetazoa:ZK328.2.1(transcript)|ensemblmetazoa:ZK328.2.2(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 rogid:ZzRMbiel6fCRqPVVylLHjMXJlWA6239 intact-crc:77D8FBD17A233C58|rigid:EBNBPDjICfNSHC/730dbKk8WilM false - sufficient binding region:734-974("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02639 uniprotkb:Q23463 intact:EBI-318115|ensemblmetazoa:C09D4.5.1|ensemblmetazoa:C09D4.5.2|ensemblmetazoa:C09D4.5.3|ensemblmetazoa:C09D4.5.4 intact:EBI-2002136|ensemblmetazoa:ZK328.2.1|ensemblmetazoa:ZK328.2.2 psi-mi:rl19_caeel(display_long)|uniprotkb:rpl-19(gene name)|psi-mi:rpl-19(display_short)|uniprotkb:C09D4.5(orf name) psi-mi:q23463_caeel(display_long)|uniprotkb:eftu-2(gene name)|psi-mi:eftu-2(display_short)|uniprotkb:CELE_ZK328.2(orf name)|uniprotkb:ZK328.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456217|imex:IM-11985-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491608.1|wormbase:C09D4.5|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-975957|ensemblmetazoa:C09D4.5.1(transcript)|ensemblmetazoa:C09D4.5.2(transcript)|ensemblmetazoa:C09D4.5.3(transcript)|ensemblmetazoa:C09D4.5.4(transcript)|ensemblmetazoa:WBGene00004431(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|reactome:R-CEL-975956|reactome:R-CEL-72706|dip:DIP-25603N refseq:NP_498308.1|wormbase:ZK328.2|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|reactome:R-CEL-72163|reactome:R-CEL-72165|interpro:IPR035647|interpro:IPR035655|interpro:IPR031950|interpro:IPR027417|interpro:IPR044121|ensemblmetazoa:WBGene00001166(gene)|ensemblmetazoa:ZK328.2.1(transcript)|ensemblmetazoa:ZK328.2.2(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:kiYoetMMOagFQob4c5AO4h7LMso6239 rogid:ZzRMbiel6fCRqPVVylLHjMXJlWA6239 intact-crc:C18751600F34AC11|rigid:c1O9ajfMNII3XlcLHDR+f2mUUaA false - sufficient binding region:734-974("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61907 uniprotkb:P90916 intact:EBI-322296|ensemblmetazoa:T27C4.4a.1 intact:EBI-324314|uniprotkb:A2JDY3|uniprotkb:O62411|ensemblmetazoa:K07A1.12.1 psi-mi:o61907_caeel(display_long)|uniprotkb:lin-40(gene name)|psi-mi:lin-40(display_short)|uniprotkb:CELE_T27C4.4(orf name)|uniprotkb:T27C4.4(orf name) psi-mi:lin53_caeel(display_long)|uniprotkb:lin-53(gene name)|psi-mi:lin-53(display_short)|uniprotkb:rba-2(gene name synonym)|uniprotkb:K07A1.12(orf name)|uniprotkb:Abnormal cell lineage protein 53(gene name synonym)|uniprotkb:Synthetic multivulva protein p48(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456207|imex:IM-11985-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504031.1|wormbase:T27C4.4a|ensemblmetazoa:T27C4.4a.1(transcript)|ensemblmetazoa:WBGene00003025(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR040138|interpro:IPR043151|dip:DIP-25278N|reactome:R-CEL-8943724|reactome:R-CEL-3214815 refseq:NP_492552.1|wormbase:K07A1.12|reactome:R-CEL-2559580|reactome:R-CEL-3214858|ensemblmetazoa:K07A1.12.1(transcript)|ensemblmetazoa:WBGene00003036(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0070176"(DRM complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|reactome:R-CEL-3214847|dip:DIP-24440N|reactome:R-CEL-8951664|reactome:R-CEL-8943724|reactome:R-CEL-1538133|reactome:R-CEL-212300|reactome:R-CEL-3214815|reactome:R-CEL-8953750 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:z/4gAcNknWYtDGQPBPDOnYBV9Vc6239 rogid:v5/7m30zbtMyaxt8xomuotdJqcA6239 intact-crc:94E7CB7351A37702|rigid:c+c6LQWZQYZObrsnpzq/+l/ypEo false sufficient binding region:735-1022("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWI6 uniprotkb:P34339 intact:EBI-317365|uniprotkb:Q7K785|ensemblmetazoa:Y54E2A.11a.1|ensemblmetazoa:Y54E2A.11a.2|ensemblmetazoa:Y54E2A.11a.3 intact:EBI-2002447|ensemblmetazoa:C27D11.1.1 psi-mi:eif3b_caeel(display_long)|uniprotkb:eif-3.B(gene name)|psi-mi:eif-3.B(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:Y54E2A.11(orf name) psi-mi:eif3a_caeel(display_long)|uniprotkb:egl-45(gene name)|psi-mi:egl-45(display_short)|uniprotkb:eif-3.A(gene name synonym)|uniprotkb:Egg-laying defective protein 45(gene name synonym)|uniprotkb:C27D11.1(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456197|imex:IM-11985-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022469.2|wormbase:Y54E2A.11a|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|refseq:NP_001022470.2|wormbase:Y54E2A.11b|ensemblmetazoa:WBGene00001225(gene)|ensemblmetazoa:Y54E2A.11a.1(transcript)|ensemblmetazoa:Y54E2A.11a.2(transcript)|ensemblmetazoa:Y54E2A.11a.3(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|dip:DIP-26989N|reactome:R-CEL-72649 refseq:NP_498698.1|wormbase:C27D11.1|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-72649|interpro:IPR027512|ensemblmetazoa:C27D11.1.1(transcript)|ensemblmetazoa:WBGene00001209(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0018991"(oviposition)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045182"(translation regulator activity)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:SR037TI5QzHk7oWIA+Kc/ISHRCs6239 rogid:ikwUVKZiw9OM16kt8JEfFxV6xW86239 intact-crc:7F2CA4DED0FC1815|rigid:4GK++a6ZSvM4/NWigElFF1rLgPc false - sufficient binding region:738-869("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFV3 uniprotkb:O02217 intact:EBI-1187461|intact:EBI-1187509|uniprotkb:G5EDA1|ensemblmetazoa:Y48A6B.11b.1 intact:EBI-1187455|uniprotkb:A5Z2U4|ensemblmetazoa:C25A1.9a.1 psi-mi:rsa2_caeel(display_long)|uniprotkb:Y48A6B.11(orf name)|uniprotkb:rsa-2(gene name)|psi-mi:rsa-2(display_short) psi-mi:p2r31_caeel(display_long)|uniprotkb:rsa-1(gene name)|psi-mi:rsa-1(display_short)|uniprotkb:Regulator of spindle assembly protein 1(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A 72kDa regulatory subunit rsa-1(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'' rsa-1(gene name synonym)|uniprotkb:C25A1.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456187|imex:IM-11985-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7YSJ2(uniprot-removed-ac)|refseq:NP_001022887.1|wormbase:Y48A6B.11b|wormbase:Y48A6B.11a|refseq:NP_001022886.1|ensemblmetazoa:WBGene00012972(gene)|ensemblmetazoa:Y48A6B.11b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0048566"(embryonic digestive tract development) refseq:NP_492683.1|wormbase:C25A1.9a|interpro:IPR011992(EF-Hand type)|refseq:NP_001122424.1|wormbase:C25A1.9b|ensemblmetazoa:C25A1.9a.1(transcript)|ensemblmetazoa:WBGene00007710(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR028846 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7PBwPJFROCL8Mv1INcviVzZGFCE6239 rogid:TzkShn9bEdl1tOgz8nIXnAHZar86239 intact-crc:C64363D6E85BD7DD|rigid:9iU+XiktTbKtmYSe5X58tffejW0 false sufficient binding region:740-874("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23463 uniprotkb:Q95Y13 intact:EBI-2002136|ensemblmetazoa:ZK328.2.1|ensemblmetazoa:ZK328.2.2 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 psi-mi:q23463_caeel(display_long)|uniprotkb:eftu-2(gene name)|psi-mi:eftu-2(display_short)|uniprotkb:CELE_ZK328.2(orf name)|uniprotkb:ZK328.2(orf name) psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456237|imex:IM-11985-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498308.1|wormbase:ZK328.2|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|reactome:R-CEL-72163|reactome:R-CEL-72165|interpro:IPR035647|interpro:IPR035655|interpro:IPR031950|interpro:IPR027417|interpro:IPR044121|ensemblmetazoa:WBGene00001166(gene)|ensemblmetazoa:ZK328.2.1(transcript)|ensemblmetazoa:ZK328.2.2(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex) ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZzRMbiel6fCRqPVVylLHjMXJlWA6239 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 intact-crc:2C60DE05151A3608|rigid:duHejdMG2W4ddTTDGMhbLOi2CAo false sufficient binding region:734-974("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:Q9BKT9 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-2005827|ensemblmetazoa:Y37E3.15a.1 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:q9bkt9_caeel(display_long)|uniprotkb:npp-13(gene name)|psi-mi:npp-13(display_short)|uniprotkb:CELE_Y37E3.15(orf name)|uniprotkb:Y37E3.15(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456282|imex:IM-11985-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N interpro:IPR007231(Nucleoporin interacting component)|refseq:NP_740802.1|wormbase:Y37E3.15a|ensemblmetazoa:WBGene00003799(gene)|ensemblmetazoa:Y37E3.15a.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1903379"(regulation of mitotic chromosome condensation)|go:"GO:1990893"(mitotic chromosome centromere condensation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:KQxxaQPFCk9tycEeORD/MJg0krY6239 intact-crc:152C7469A30F8FCC|rigid:WWImkKY7zS7EvJWVkyrKSuVfD/M false sufficient binding region:2-328("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:Q23463 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-2002136|ensemblmetazoa:ZK328.2.1|ensemblmetazoa:ZK328.2.2 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:q23463_caeel(display_long)|uniprotkb:eftu-2(gene name)|psi-mi:eftu-2(display_short)|uniprotkb:CELE_ZK328.2(orf name)|uniprotkb:ZK328.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456272|imex:IM-11985-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N refseq:NP_498308.1|wormbase:ZK328.2|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|reactome:R-CEL-72163|reactome:R-CEL-72165|interpro:IPR035647|interpro:IPR035655|interpro:IPR031950|interpro:IPR027417|interpro:IPR044121|ensemblmetazoa:WBGene00001166(gene)|ensemblmetazoa:ZK328.2.1(transcript)|ensemblmetazoa:ZK328.2.2(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:ZzRMbiel6fCRqPVVylLHjMXJlWA6239 intact-crc:34B3AD14491C178F|rigid:56CMZiP68PbZavAJLzU+9Bp3tDc false - sufficient binding region:734-974("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q23463 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-2002136|ensemblmetazoa:ZK328.2.1|ensemblmetazoa:ZK328.2.2 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q23463_caeel(display_long)|uniprotkb:eftu-2(gene name)|psi-mi:eftu-2(display_short)|uniprotkb:CELE_ZK328.2(orf name)|uniprotkb:ZK328.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456262|imex:IM-11985-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) refseq:NP_498308.1|wormbase:ZK328.2|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|reactome:R-CEL-72163|reactome:R-CEL-72165|interpro:IPR035647|interpro:IPR035655|interpro:IPR031950|interpro:IPR027417|interpro:IPR044121|ensemblmetazoa:WBGene00001166(gene)|ensemblmetazoa:ZK328.2.1(transcript)|ensemblmetazoa:ZK328.2.2(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:ZzRMbiel6fCRqPVVylLHjMXJlWA6239 intact-crc:BA276C6B11237925|rigid:SN18B3ohSt9NkS7a7MAIhLVO3N0 false - sufficient binding region:734-974("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23463 uniprotkb:Q95XY1 intact:EBI-2002136|ensemblmetazoa:ZK328.2.1|ensemblmetazoa:ZK328.2.2 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:q23463_caeel(display_long)|uniprotkb:eftu-2(gene name)|psi-mi:eftu-2(display_short)|uniprotkb:CELE_ZK328.2(orf name)|uniprotkb:ZK328.2(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456252|imex:IM-11985-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498308.1|wormbase:ZK328.2|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|reactome:R-CEL-72163|reactome:R-CEL-72165|interpro:IPR035647|interpro:IPR035655|interpro:IPR031950|interpro:IPR027417|interpro:IPR044121|ensemblmetazoa:WBGene00001166(gene)|ensemblmetazoa:ZK328.2.1(transcript)|ensemblmetazoa:ZK328.2.2(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZzRMbiel6fCRqPVVylLHjMXJlWA6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:166E8B7399FD77F1|rigid:swSL+v2kCGZ3D6++E0w/H9o5EgE false sufficient binding region:734-974("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76406 uniprotkb:Q9GRY9 intact:EBI-1175918|ensemblmetazoa:T10B5.6.1 intact:EBI-320508|ensemblmetazoa:Y59A8B.10a.1|ensemblmetazoa:Y59A8B.10a.2|ensemblmetazoa:Y59A8B.10a.3 psi-mi:o76406_caeel(display_long)|uniprotkb:knl-3(gene name)|psi-mi:knl-3(display_short)|uniprotkb:CELE_T10B5.6(orf name)|uniprotkb:T10B5.6(orf name) psi-mi:q9gry9_caeel(display_long)|uniprotkb:nova-1(gene name)|psi-mi:nova-1(display_short)|uniprotkb:CELE_Y59A8B.10(orf name)|uniprotkb:Y59A8B.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456327|imex:IM-11985-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_503520.1|wormbase:T10B5.6|ensemblmetazoa:T10B5.6.1(transcript)|ensemblmetazoa:WBGene00020392(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1905561"(positive regulation of kinetochore assembly) wormbase:Y59A8B.10a|ensemblmetazoa:WBGene00013347(gene)|ensemblmetazoa:Y59A8B.10a.1(transcript)|ensemblmetazoa:Y59A8B.10a.2(transcript)|ensemblmetazoa:Y59A8B.10a.3(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|refseq:NP_001256769.1|dip:DIP-24651N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:YdVt0+9h0bkfHGwA9xNuJiWIimo6239 rogid:gInq7hxk90pbcpjxNwzmjqwdm+U6239 intact-crc:6D2F6C5377570578|rigid:pk6rnQsLxoDB+TV7YLlauyCTnSI false - sufficient binding region:70-413("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8IU00 uniprotkb:P91820 intact:EBI-6456292|ensemblmetazoa:Y73B6BL.38.1 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 psi-mi:q8iu00_caeel(display_long)|uniprotkb:Y73B6BL.38(orf name)|uniprotkb:puf-11(gene name)|psi-mi:puf-11(display_short)|uniprotkb:CELE_Y73B6BL.38(orf name) psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456297|imex:IM-11985-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022257(gene)|ensemblmetazoa:Y73B6BL.38.1(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|interpro:IPR033712|interpro:IPR033133|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_741425.1|wormbase:Y73B6BL.38 wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2018/04/06 rogid:ehoUpNZTukhqYuNTttotQ6vThvQ6239 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 intact-crc:9C46F0409FC2F61F|rigid:ZYD6F9VuJZw/FTv9BsAQUa/FMsg false - sufficient binding region:2-328("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34690 uniprotkb:G5ECL1 intact:EBI-324736|intact:EBI-2002829|uniprotkb:Q95QR1|ensemblmetazoa:C47B2.3.1|ensemblmetazoa:C47B2.3.2|ensemblmetazoa:C47B2.3.3 intact:EBI-2002824|ensemblmetazoa:M05D6.2.1 psi-mi:tba2_caeel(display_long)|uniprotkb:tba-2(gene name)|psi-mi:tba-2(display_short)|uniprotkb:C47B2.3(orf name) psi-mi:g5ecl1_caeel(display_long)|uniprotkb:M05D6.2(orf name)|uniprotkb:CELE_M05D6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456307|imex:IM-11985-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q20409(uniprot-removed-ac)|refseq:NP_001021050.1|wormbase:C47B2.3|rcsb pdb:6E88|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|ensemblmetazoa:C47B2.3.1(transcript)|ensemblmetazoa:C47B2.3.2(transcript)|ensemblmetazoa:C47B2.3.3(transcript)|ensemblmetazoa:WBGene00006529(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051642"(centrosome localization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-CEL-6807878|reactome:R-CEL-6811436|reactome:R-CEL-114608|reactome:R-CEL-5620924|reactome:R-CEL-9013407|reactome:R-CEL-3371497 uniprotkb:Q21520(uniprot-removed-ac)|interpro:IPR008862(T-complex 11)|refseq:NP_495787.2|wormbase:M05D6.2|ensemblmetazoa:M05D6.2.1(transcript)|ensemblmetazoa:WBGene00010875(gene)|go:"GO:0007165"(signal transduction) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BWnYXKv3G4Z+nHRI6GjAYPoLTuk6239 rogid:R4L5AGl+TXSchDtPx2bSZ4sGgbc6239 intact-crc:C1E1062A7AB4112E|rigid:P8vh3OAEfn8t6HyuP1GcrO7aHhg false - sufficient binding region:71-521("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18239 uniprotkb:G5ECY0 intact:EBI-314248|ensemblmetazoa:C27A2.6.1 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:q18239_caeel(display_long)|uniprotkb:dsh-2(gene name)|psi-mi:dsh-2(display_short)|uniprotkb:CELE_C27A2.6(orf name)|uniprotkb:C27A2.6(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456317|imex:IM-11985-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C27A2.6|reactome:R-CEL-201688|reactome:R-CEL-4086400|reactome:R-CEL-4641258|ensemblmetazoa:C27A2.6.1(transcript)|ensemblmetazoa:WBGene00001102(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070986"(left/right axis specification)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR026542|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|reactome:R-CEL-5663220|refseq:NP_494937.4|dip:DIP-24740N|reactome:R-CEL-5099900|reactome:R-CEL-2028269|reactome:R-CEL-4641262|reactome:R-CEL-8856825|reactome:R-CEL-8856828 uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2015/12/04 rogid:yDb25aMPWu/bsUAWs6+ZIhpWpOU6239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:A9E5EA9C97071A3F|rigid:daH/cBBPomAtyDPj4boHrLFnl24 false sufficient binding region:70->599("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NDC9 uniprotkb:P13508 intact:EBI-2004982|uniprotkb:O45742|ensemblmetazoa:T03F6.5.1 intact:EBI-319522|ensemblmetazoa:F02A9.6.1 psi-mi:lis1_caeel(display_long)|uniprotkb:pnm-1(gene name synonym)|uniprotkb:Pronuclear migration abnormal protein 1(gene name synonym)|uniprotkb:T03F6.5(orf name)|uniprotkb:lis-1(gene name)|psi-mi:lis-1(display_short) psi-mi:glp1_caeel(display_long)|uniprotkb:glp-1(gene name)|psi-mi:glp-1(display_short)|uniprotkb:emb-33(gene name synonym)|uniprotkb:F02A9.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456381|imex:IM-11985-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_499755.1|wormbase:T03F6.5|interpro:IPR017252(Dynein regulator)|interpro:IPR020472|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|reactome:R-CEL-6811436|interpro:IPR036322|interpro:IPR037190|ensemblmetazoa:T03F6.5.1(transcript)|ensemblmetazoa:WBGene00003047(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005818"(aster)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007281"(germ cell development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040011"(locomotion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070840"(dynein complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity) refseq:NP_499014.1|wormbase:F02A9.6|ensemblmetazoa:F02A9.6.1(transcript)|ensemblmetazoa:WBGene00001609(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR002110(Ankyrin)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|go:"GO:0005886"(plasma membrane)|interpro:IPR018097|interpro:IPR020683|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0012505"(endomembrane system)|interpro:IPR035993|interpro:IPR036770|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043055"(maintenance of dauer)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|dip:DIP-26562N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:QdvWBwu6LtFK8AkjBexVkZtwO1M6239 rogid:gJCULzDV99yj+GQn/Hel9r2t+lw6239 intact-crc:C33CDA87E916DA44|rigid:dT6JQRYwRoVonEEqLegTOha/BeA false - sufficient binding region:68-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P13508 uniprotkb:Q9XVP0 intact:EBI-319522|ensemblmetazoa:F02A9.6.1 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 psi-mi:glp1_caeel(display_long)|uniprotkb:glp-1(gene name)|psi-mi:glp-1(display_short)|uniprotkb:emb-33(gene name synonym)|uniprotkb:F02A9.6(orf name) psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456361|imex:IM-11985-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499014.1|wormbase:F02A9.6|ensemblmetazoa:F02A9.6.1(transcript)|ensemblmetazoa:WBGene00001609(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR002110(Ankyrin)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|go:"GO:0005886"(plasma membrane)|interpro:IPR018097|interpro:IPR020683|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0012505"(endomembrane system)|interpro:IPR035993|interpro:IPR036770|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043055"(maintenance of dauer)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|dip:DIP-26562N refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gJCULzDV99yj+GQn/Hel9r2t+lw6239 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 intact-crc:7A7E625991475D48|rigid:FAsHavSx+sO0mrn0foikhgK+3BQ false sufficient binding region:68-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7YTG9 uniprotkb:P13508 intact:EBI-2003102|ensemblmetazoa:F11A10.8.1|ensemblmetazoa:F11A10.8.2 intact:EBI-319522|ensemblmetazoa:F02A9.6.1 psi-mi:q7ytg9_caeel(display_long)|uniprotkb:cpsf-4(gene name)|psi-mi:cpsf-4(display_short)|uniprotkb:CELE_F11A10.8(orf name)|uniprotkb:F11A10.8(orf name) psi-mi:glp1_caeel(display_long)|uniprotkb:glp-1(gene name)|psi-mi:glp-1(display_short)|uniprotkb:emb-33(gene name synonym)|uniprotkb:F02A9.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456351|imex:IM-11985-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023126.1|wormbase:F11A10.8|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|interpro:IPR036855|interpro:IPR036875|reactome:R-CEL-73856|ensemblmetazoa:F11A10.8.1(transcript)|ensemblmetazoa:F11A10.8.2(transcript)|ensemblmetazoa:WBGene00044329(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation) refseq:NP_499014.1|wormbase:F02A9.6|ensemblmetazoa:F02A9.6.1(transcript)|ensemblmetazoa:WBGene00001609(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR002110(Ankyrin)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|go:"GO:0005886"(plasma membrane)|interpro:IPR018097|interpro:IPR020683|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0012505"(endomembrane system)|interpro:IPR035993|interpro:IPR036770|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043055"(maintenance of dauer)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|dip:DIP-26562N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hFzrsuwJxyQatMLkejzDei/oxYw6239 rogid:gJCULzDV99yj+GQn/Hel9r2t+lw6239 intact-crc:DD7FFF65AD9C1C8F|rigid:A6T/E2gWuDHBvYZIuMbKDeVcPvE false - sufficient binding region:68-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6456340 uniprotkb:G5ECY0 intact:EBI-6306333 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:ebi6306333(display_short)|psi-mi:EBI-6456340(display_long)|intact:B0250.7(author assigned name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456337|imex:IM-11985-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:92F7F9C08AF43A78 false - sufficient binding region:68-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XUS9 uniprotkb:P13508 intact:EBI-315948|ensemblmetazoa:K08E3.6.1|ensemblmetazoa:K08E3.6.2 intact:EBI-319522|ensemblmetazoa:F02A9.6.1 psi-mi:q9xus9_caeel(display_long)|uniprotkb:cyk-4(gene name)|psi-mi:cyk-4(display_short)|uniprotkb:CELE_K08E3.6(orf name)|uniprotkb:K08E3.6(orf name) psi-mi:glp1_caeel(display_long)|uniprotkb:glp-1(gene name)|psi-mi:glp-1(display_short)|uniprotkb:emb-33(gene name synonym)|uniprotkb:F02A9.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456371|imex:IM-11985-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-983189|refseq:NP_499845.1|wormbase:K08E3.6|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|ensemblmetazoa:K08E3.6.1(transcript)|ensemblmetazoa:K08E3.6.2(transcript)|ensemblmetazoa:WBGene00000875(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990386"(mitotic cleavage furrow ingression)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-25057N refseq:NP_499014.1|wormbase:F02A9.6|ensemblmetazoa:F02A9.6.1(transcript)|ensemblmetazoa:WBGene00001609(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR002110(Ankyrin)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|go:"GO:0005886"(plasma membrane)|interpro:IPR018097|interpro:IPR020683|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0012505"(endomembrane system)|interpro:IPR035993|interpro:IPR036770|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043055"(maintenance of dauer)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|dip:DIP-26562N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KHkQNZBkhUbn2rQE9+8+uvbQrzo6239 rogid:gJCULzDV99yj+GQn/Hel9r2t+lw6239 intact-crc:D1C96B88B2B7E091|rigid:AF+ALd2uGlo4tCFjB301UEdpkJM false - sufficient binding region:68-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P13508 uniprotkb:Q95QC4 intact:EBI-319522|ensemblmetazoa:F02A9.6.1 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 psi-mi:glp1_caeel(display_long)|uniprotkb:glp-1(gene name)|psi-mi:glp-1(display_short)|uniprotkb:emb-33(gene name synonym)|uniprotkb:F02A9.6(orf name) psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456406|imex:IM-11985-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499014.1|wormbase:F02A9.6|ensemblmetazoa:F02A9.6.1(transcript)|ensemblmetazoa:WBGene00001609(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR002110(Ankyrin)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|go:"GO:0005886"(plasma membrane)|interpro:IPR018097|interpro:IPR020683|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0012505"(endomembrane system)|interpro:IPR035993|interpro:IPR036770|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043055"(maintenance of dauer)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|dip:DIP-26562N refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gJCULzDV99yj+GQn/Hel9r2t+lw6239 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 intact-crc:4046B1A15F7C1CD6|rigid:WkqFxNctLBeDh6qfMb3anjb9RHk false sufficient binding region:68-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10039 uniprotkb:P13508 intact:EBI-326683|ensemblmetazoa:T10F2.1a.1 intact:EBI-319522|ensemblmetazoa:F02A9.6.1 psi-mi:gars_caeel(display_long)|uniprotkb:gars-1(gene name)|psi-mi:gars-1(display_short)|uniprotkb:Diadenosine tetraphosphate synthetase(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase(gene name synonym)|uniprotkb:grs-1(gene name synonym)|uniprotkb:T10F2.1(orf name) psi-mi:glp1_caeel(display_long)|uniprotkb:glp-1(gene name)|psi-mi:glp-1(display_short)|uniprotkb:emb-33(gene name synonym)|uniprotkb:F02A9.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456416|imex:IM-11985-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498093.1|wormbase:T10F2.1a|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004154(Anticodon-binding)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR002315(Glycyl-tRNA synthetase, alpha2 dimer)|interpro:IPR000738(WHEP-TRS)|ensemblmetazoa:WBGene00001744(gene)|go:"GO:0004820"(glycine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006426"(glycyl-tRNA aminoacylation)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016740"(transferase activity)|go:"GO:0030424"(axon)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070150"(mitochondrial glycyl-tRNA aminoacylation)|ensemblmetazoa:T10F2.1a.1(transcript)|interpro:IPR027031|interpro:IPR033731|interpro:IPR036621 refseq:NP_499014.1|wormbase:F02A9.6|ensemblmetazoa:F02A9.6.1(transcript)|ensemblmetazoa:WBGene00001609(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR002110(Ankyrin)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|go:"GO:0005886"(plasma membrane)|interpro:IPR018097|interpro:IPR020683|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0012505"(endomembrane system)|interpro:IPR035993|interpro:IPR036770|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043055"(maintenance of dauer)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|dip:DIP-26562N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WZxYG3trmRoGa3x5OKWLW1p4bfw6239 rogid:gJCULzDV99yj+GQn/Hel9r2t+lw6239 intact-crc:C19004D9F8A4FE93|rigid:LphO0fVP/iud1KIdvZPSoYja7kE false - sufficient binding region:68-336("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BKT9 uniprotkb:P91457 intact:EBI-2005827|ensemblmetazoa:Y37E3.15a.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:q9bkt9_caeel(display_long)|uniprotkb:npp-13(gene name)|psi-mi:npp-13(display_short)|uniprotkb:CELE_Y37E3.15(orf name)|uniprotkb:Y37E3.15(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456426|imex:IM-11985-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007231(Nucleoporin interacting component)|refseq:NP_740802.1|wormbase:Y37E3.15a|ensemblmetazoa:WBGene00003799(gene)|ensemblmetazoa:Y37E3.15a.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1903379"(regulation of mitotic chromosome condensation)|go:"GO:1990893"(mitotic chromosome centromere condensation) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KQxxaQPFCk9tycEeORD/MJg0krY6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:B5FED8FA65587A31|rigid:VuyQUONwRvjDY1wme1WU/d2glZI false - sufficient binding region:68-336("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34278 uniprotkb:P34286 intact:EBI-313751|ensemblmetazoa:C02F5.1.1 intact:EBI-313778|uniprotkb:Q9BMU3|ensemblmetazoa:C02F5.9.1 psi-mi:knl1_caeel(display_long)|uniprotkb:C02F5.1(orf name)|uniprotkb:knl-1(gene name)|psi-mi:knl-1(display_short) psi-mi:psb1_caeel(display_long)|uniprotkb:pbs-6(gene name)|psi-mi:pbs-6(display_short)|uniprotkb:C02F5.9(orf name)|uniprotkb:Proteasome subunit beta 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456436|imex:IM-11985-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498811.1|wormbase:C02F5.1|ensemblmetazoa:C02F5.1.1(transcript)|ensemblmetazoa:WBGene00002231(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005694"(chromosome)|go:"GO:0005938"(cell cortex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051301"(cell division)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|dip:DIP-25115N reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_498806.1|wormbase:C02F5.9|reactome:R-CEL-5632684|ensemblmetazoa:C02F5.9.1(transcript)|ensemblmetazoa:WBGene00003952(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-24619N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:3DFBj4SOezj3CRsizwC0biCAfUQ6239 rogid:g54+kg5aHsaQMTBH6xZ9h0/20XQ6239 intact-crc:E103132C05305A90|rigid:faFuDoMswFFzewq3nF83C3MIUtw false sufficient binding region:68-273("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P13508 uniprotkb:Q8I711 intact:EBI-319522|ensemblmetazoa:F02A9.6.1 intact:EBI-6456394|ensemblmetazoa:T10F2.1b.1 psi-mi:glp1_caeel(display_long)|uniprotkb:glp-1(gene name)|psi-mi:glp-1(display_short)|uniprotkb:emb-33(gene name synonym)|uniprotkb:F02A9.6(orf name) psi-mi:q8i711_caeel(display_long)|uniprotkb:gars-1(gene name)|psi-mi:gars-1(display_short)|uniprotkb:Glycine--tRNA ligase(gene name synonym)|uniprotkb:CELE_T10F2.1(orf name)|uniprotkb:T10F2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456391|imex:IM-11985-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499014.1|wormbase:F02A9.6|ensemblmetazoa:F02A9.6.1(transcript)|ensemblmetazoa:WBGene00001609(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR002110(Ankyrin)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|go:"GO:0005886"(plasma membrane)|interpro:IPR018097|interpro:IPR020683|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0012505"(endomembrane system)|interpro:IPR035993|interpro:IPR036770|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043055"(maintenance of dauer)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|dip:DIP-26562N ensemblmetazoa:T10F2.1b.1(transcript)|ensemblmetazoa:WBGene00001744(gene)|go:"GO:0004820"(glycine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006426"(glycyl-tRNA aminoacylation)|go:"GO:0016740"(transferase activity)|interpro:IPR033731|interpro:IPR027031|interpro:IPR000738(WHEP-TRS)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002315(Glycyl-tRNA synthetase, alpha2 dimer)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|refseq:NP_871640.1|wormbase:T10F2.1b|interpro:IPR036621 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gJCULzDV99yj+GQn/Hel9r2t+lw6239 rogid:gkHJId9s+GIJ2kCoYrSi93i34BY6239 intact-crc:F98F337549E2D2B9|rigid:rLget1Dj9bSiNBMoi5jfmrn5PZA false sufficient binding region:68-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91918 uniprotkb:Q09248 intact:EBI-895974|ensemblmetazoa:W08E3.1.1 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 psi-mi:rsmb_caeel(display_long)|uniprotkb:snr-2(gene name)|psi-mi:snr-2(display_short)|uniprotkb:W08E3.1(orf name)|uniprotkb:Sm protein B(gene name synonym) psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456481|imex:IM-11985-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493348.1|wormbase:W08E3.1|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|reactome:R-CEL-72163|reactome:R-CEL-72165|reactome:R-CEL-111367|reactome:R-CEL-191859|reactome:R-CEL-73856|reactome:R-CEL-77588|ensemblmetazoa:W08E3.1.1(transcript)|ensemblmetazoa:WBGene00004915(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome) refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:AI8EhTdY6yoN4nhakXh2/TT73nY6239 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 intact-crc:6F7696916B225B43|rigid:S47bmqQN4JpArpQSfy7yc6uMwQI false - sufficient binding region:67-227("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EG29 uniprotkb:Q9XVU8 intact:EBI-2005638|ensemblmetazoa:C06C3.1d.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:g5eg29_caeel(display_long)|uniprotkb:CELE_C06C3.1(orf name)|uniprotkb:mel-11(gene name)|psi-mi:mel-11(display_short)|uniprotkb:C06C3.1(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456471|imex:IM-11985-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6BEV7(uniprot-removed-ac)|interpro:IPR031775|interpro:IPR002110(Ankyrin)|interpro:IPR020683|refseq:NP_001021929.1|wormbase:C06C3.1d|interpro:IPR036770|ensemblmetazoa:C06C3.1d.1(transcript)|ensemblmetazoa:WBGene00003196(gene)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0048598"(embryonic morphogenesis) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ITF19tp2RcqCUs9em/i5J5LzDaU6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:0EA9D5ECA637F4CA|rigid:8BP0y3ATlrt1Zfsie1ILtFoFvps false sufficient binding region:672-968("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:Q18076 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-2921846|ensemblmetazoa:C18B2.5a.1 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:q18076_caeel(display_long)|uniprotkb:C18B2.5(orf name)|uniprotkb:CELE_C18B2.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456461|imex:IM-11985-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 ensemblmetazoa:C18B2.5a.1(transcript)|ensemblmetazoa:WBGene00015956(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|interpro:IPR027417|refseq:NP_741750.1|wormbase:C18B2.5a|dip:DIP-25136N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:mcd3NaSPJ6tU4fMyCuPRAuL4QOw6239 intact-crc:43FC62ABF05F4AA7|rigid:QZQuRsKiyCQRecPodbA7A1CJlMc false - sufficient binding region:67-673("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34331-2 uniprotkb:P91870 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 intact:EBI-320962|ensemblmetazoa:F32H2.3.1|ensemblmetazoa:F32H2.3.2 psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:spd2_caeel(display_long)|uniprotkb:F32H2.3(orf name)|uniprotkb:spd-2(gene name)|psi-mi:spd-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456451|imex:IM-11985-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) refseq:NP_492414.1|wormbase:F32H2.3|ensemblmetazoa:F32H2.3.1(transcript)|ensemblmetazoa:F32H2.3.2(transcript)|ensemblmetazoa:WBGene00004953(gene)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019901"(protein kinase binding)|go:"GO:0040025"(vulval development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR039103|dip:DIP-25500N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:u830S0jdkV753ilx7DbxmhPocv86239 rogid:GBGtZRHVbrFLFhWQy/m9+L17Etk6239 intact-crc:F0B3FCF4D6A516CB|rigid:prGr0hRqAYE/kS7EEPesLZh5TUM false - sufficient binding region:68-269("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09248 uniprotkb:O76258 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 intact:EBI-2002148|ensemblmetazoa:C09G12.9.1 psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:o76258_caeel(display_long)|uniprotkb:tsg-101(gene name)|psi-mi:tsg-101(display_short)|uniprotkb:CELE_C09G12.9(orf name)|uniprotkb:C09G12.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456521|imex:IM-11985-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 refseq:NP_500364.2|wormbase:C09G12.9|interpro:IPR017916|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR008883(Tumour susceptibility gene 101)|reactome:R-CEL-917729|interpro:IPR037202|ensemblmetazoa:C09G12.9.1(transcript)|ensemblmetazoa:WBGene00015658(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 rogid:tAhzbKmVoJZA+IwR6RLdGgDFIYI6239 intact-crc:A43FD21BA827A6F2|rigid:QZYUsa3TnVb7Ka2o1BOxHA+Xbck false sufficient binding region:67-192("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18282 uniprotkb:P34331-2 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456511|imex:IM-11985-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 rogid:u830S0jdkV753ilx7DbxmhPocv86239 intact-crc:06F605A0A13E0AC8|rigid:KJu0dndH6EQdgPSAeLM6kyI14O0 false sufficient binding region:67-193("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93233 uniprotkb:Q95XY1 intact:EBI-313525|ensemblmetazoa:C17E4.5.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:q93233_caeel(display_long)|uniprotkb:pabp-2(gene name)|psi-mi:pabp-2(display_short)|uniprotkb:CELE_C17E4.5(orf name)|uniprotkb:C17E4.5(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456501|imex:IM-11985-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|refseq:NP_492504.1|wormbase:C17E4.5|ensemblmetazoa:C17E4.5.1(transcript)|ensemblmetazoa:WBGene00003904(gene)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|dip:DIP-26233N|reactome:R-CEL-73856 refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:UQ8eYmFDtdGomnt6MTsw6TJaLno6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:F9C8058B6D40501C|rigid:KfK6CcnR4gZTs5NEHSpgqBB529I false sufficient binding region:67-205("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21735 uniprotkb:P91457 intact:EBI-2004567|ensemblmetazoa:R05D11.3.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:ntf2_caeel(display_long)|uniprotkb:ran-4(gene name)|psi-mi:ran-4(display_short)|uniprotkb:R05D11.3(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456531|imex:IM-11985-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492322.1|wormbase:R05D11.3|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|ensemblmetazoa:R05D11.3.1(transcript)|ensemblmetazoa:WBGene00004305(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0044613"(nuclear pore central transport channel) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:MO3nF45y4Qnv1bnk707RFa3N6hU6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:C1D02BD9F550DCB4|rigid:b+/zs+8UwaU1lbAtMbYuOTn9VJQ false - sufficient binding region:671-805("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93233 uniprotkb:Q93233 intact:EBI-313525|ensemblmetazoa:C17E4.5.1 intact:EBI-313525|ensemblmetazoa:C17E4.5.1 psi-mi:q93233_caeel(display_long)|uniprotkb:pabp-2(gene name)|psi-mi:pabp-2(display_short)|uniprotkb:CELE_C17E4.5(orf name)|uniprotkb:C17E4.5(orf name) psi-mi:q93233_caeel(display_long)|uniprotkb:pabp-2(gene name)|psi-mi:pabp-2(display_short)|uniprotkb:CELE_C17E4.5(orf name)|uniprotkb:C17E4.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456491|imex:IM-11985-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|refseq:NP_492504.1|wormbase:C17E4.5|ensemblmetazoa:C17E4.5.1(transcript)|ensemblmetazoa:WBGene00003904(gene)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|dip:DIP-26233N|reactome:R-CEL-73856 reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|refseq:NP_492504.1|wormbase:C17E4.5|ensemblmetazoa:C17E4.5.1(transcript)|ensemblmetazoa:WBGene00003904(gene)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|dip:DIP-26233N|reactome:R-CEL-73856 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:UQ8eYmFDtdGomnt6MTsw6TJaLno6239 rogid:UQ8eYmFDtdGomnt6MTsw6TJaLno6239 intact-crc:FED8221D07A2ED91|rigid:1GXZpCwzfDLGj6Xj3cyk8AyPwDg false sufficient binding region:67-205("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17607 uniprotkb:Q8WT44 intact:EBI-316213|ensemblmetazoa:C27H6.2.1 intact:EBI-2002025|uniprotkb:G5EDU8|ensemblmetazoa:ZK328.1b.1 psi-mi:ruvb1_caeel(display_long)|uniprotkb:ruvb-1(gene name)|psi-mi:ruvb-1(display_short)|uniprotkb:Pontin(gene name synonym)|uniprotkb:C27H6.2(orf name) psi-mi:ubph_caeel(display_long)|uniprotkb:CeUBP130(gene name synonym)|uniprotkb:Cytokinesis defective protein 3(gene name synonym)|uniprotkb:uch-1(gene name synonym)|uniprotkb:ZK328.1(orf name)|uniprotkb:cyk-3(gene name)|psi-mi:cyk-3(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456571|imex:IM-11985-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505567.2|reactome:R-CEL-5689880|wormbase:C27H6.2|ensemblmetazoa:C27H6.2.1(transcript)|ensemblmetazoa:WBGene00007784(gene)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0002119"(nematode larval development)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|dip:DIP-25966N refseq:NP_001022992.1|wormbase:ZK328.1b|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|refseq:NP_498311.2|interpro:IPR035927|interpro:IPR038765|wormbase:ZK328.1a|reactome:R-CEL-5689880|ensemblmetazoa:WBGene00000874(gene)|ensemblmetazoa:ZK328.1b.1(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904785"(regulation of asymmetric protein localization involved in cell fate determination)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ClLKmYAiHB+gCDwvg9vaeL2MIxc6239 rogid:LbOi5WL6TFO24ZC3+KhxtzJ/8ZY6239 intact-crc:A9029BD03E5E2150|rigid:SbBqnbrMsR+84TeMJcfE2ljOQLM false - sufficient binding region:662-867("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:Q18529 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-314884|ensemblmetazoa:C39D10.7.2|ensemblmetazoa:C39D10.7.1 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q18529_caeel(display_long)|uniprotkb:C39D10.7(orf name)|uniprotkb:CELE_C39D10.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456561|imex:IM-11985-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 refseq:NP_509334.3|wormbase:C39D10.7|ensemblmetazoa:C39D10.7.2(transcript)|ensemblmetazoa:WBGene00016534(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|ensemblmetazoa:C39D10.7.1(transcript)|dip:DIP-27006N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:gnU6jSkV05zYFXSGRFYUIcPLW5Q6239 intact-crc:59BC87904BE77C23|rigid:Nl5YOHUJ2gQYYBl3oOw5d8JDiQ8 false - sufficient binding region:668-1171("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P20163 uniprotkb:Q9GYK4 intact:EBI-327420|uniprotkb:O02085|ensemblmetazoa:F43E2.8a.1|ensemblmetazoa:F43E2.8a.2 intact:EBI-2003638|ensemblmetazoa:T27F7.1.1|ensemblmetazoa:T27F7.1.2|ensemblmetazoa:T27F7.1.3 psi-mi:bibh_caeel(display_long)|uniprotkb:hsp-4(gene name)|psi-mi:hsp-4(display_short)|uniprotkb:hsp70d(gene name synonym)|uniprotkb:F43E2.8(orf name)|uniprotkb:Heat shock 70 kDa protein D(gene name synonym) psi-mi:q9gyk4_caeel(display_long)|uniprotkb:vps-24(gene name)|psi-mi:vps-24(display_short)|uniprotkb:CELE_T27F7.1(orf name)|uniprotkb:T27F7.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456551|imex:IM-11985-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495536.1|wormbase:F43E2.8a|ensemblmetazoa:F43E2.8a.1(transcript)|ensemblmetazoa:F43E2.8a.2(transcript)|ensemblmetazoa:WBGene00002008(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|rcsb pdb:2OP6|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|dip:DIP-26704N refseq:NP_494919.1|wormbase:T27F7.1|interpro:IPR005024(Snf7)|reactome:R-CEL-1632852|reactome:R-CEL-917729|reactome:R-CEL-9668328|ensemblmetazoa:T27F7.1.1(transcript)|ensemblmetazoa:T27F7.1.2(transcript)|ensemblmetazoa:T27F7.1.3(transcript)|ensemblmetazoa:WBGene00020866(gene)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005771"(multivesicular body)|go:"GO:0015031"(protein transport)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:1OTImKHWwZAUWM6xI9ePrkRSAks6239 rogid:ELGMjkMWI4cJudS5glpo7hzI/ak6239 intact-crc:0DC7A5C41DFED1BE|rigid:aqyd7ZjnuJbaGkL2U6eM9S/W+Ws false - sufficient binding region:67-166("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XU12 uniprotkb:Q9XVH6 intact:EBI-325126|ensemblmetazoa:K11D9.1a.1 intact:EBI-2005572|ensemblmetazoa:W01G7.3.1|ensemblmetazoa:W01G7.3.2 psi-mi:q9xu12_caeel(display_long)|uniprotkb:klp-7(gene name)|psi-mi:klp-7(display_short)|uniprotkb:CELE_K11D9.1(orf name)|uniprotkb:K11D9.1(orf name) psi-mi:rpb11_caeel(display_long)|uniprotkb:DNA-directed RNA polymerase II subunit J(gene name synonym)|uniprotkb:W01G7.3(orf name)|uniprotkb:rpb-11(gene name)|psi-mi:rpb-11(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456541|imex:IM-11985-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022677.1|wormbase:K11D9.1a|ensemblmetazoa:K11D9.1a.1(transcript)|ensemblmetazoa:WBGene00002219(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010938"(cytoplasmic microtubule depolymerization)|go:"GO:0018991"(oviposition)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|dip:DIP-26934N|reactome:R-CEL-983189 reactome:R-CEL-9018519|refseq:NP_496942.1|wormbase:W01G7.3|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR037685|reactome:R-CEL-113418|reactome:R-CEL-674695|reactome:R-CEL-72086|reactome:R-CEL-72163|reactome:R-CEL-72165|reactome:R-CEL-73776|reactome:R-CEL-73779|reactome:R-CEL-75953|reactome:R-CEL-76042|reactome:R-CEL-77075|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-5578749|reactome:R-CEL-75955|reactome:R-CEL-6796648|reactome:R-CEL-6803529|reactome:R-CEL-6807505|interpro:IPR036603|reactome:R-CEL-112382|ensemblmetazoa:W01G7.3.1(transcript)|ensemblmetazoa:W01G7.3.2(transcript)|ensemblmetazoa:WBGene00012187(gene)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0046983"(protein dimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CHfEKYlTwlJs6zeaXZrs0KLrlSI6239 rogid:PFQWLQzg4Z6p3Qt6OHD15MaZ9B46239 intact-crc:8F33B4214346C606|rigid:+Yfieka0ciwXLN+LekWV0ztR44E false sufficient binding region:671-747("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:P91820 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456611|imex:IM-11985-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2018/04/06 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 intact-crc:D27F1F11408AF48E|rigid:XoncJYOF1+GoIy0LLXDd7H1M/OM false - sufficient binding region:13-328("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:G5ECY0 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456581|imex:IM-11985-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:53D7C1877BF13252|rigid:SJLUL3xbPfOHGX97gYrRt9nWJPI false sufficient binding region:?-?("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:P39745-1 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456591|imex:IM-11985-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 intact-crc:392CAD2A99355A92|rigid:51TiReSFd2zyN58/OsBurn7iTPA false sufficient binding region:13-328("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91820 uniprotkb:O62333 intact:EBI-313618|ensemblmetazoa:T22A3.3a.1 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 psi-mi:p91820_caeel(display_long)|uniprotkb:lst-1(gene name)|psi-mi:lst-1(display_short)|uniprotkb:CELE_T22A3.3(orf name)|uniprotkb:T22A3.3(orf name) psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456601|imex:IM-11985-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:T22A3.3a|ensemblmetazoa:T22A3.3a.1(transcript)|ensemblmetazoa:WBGene00003083(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|rcsb pdb:6PUN|dip:DIP-25421N interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2018/04/06 rogid:Um/IKRKN6GsC9fV0JfSSs7+15w06239 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 intact-crc:F52744BC452B94F2|rigid:r9AXbnbI8gicTij+XrgV6WqqxN0 false sufficient binding region:13-328("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17836 uniprotkb:Q23539 intact:EBI-2003258|ensemblmetazoa:F25H5.3a.1 intact:EBI-2003265|ensemblmetazoa:ZK593.1a.1 psi-mi:o17836_caeel(display_long)|uniprotkb:F25H5.3(orf name)|uniprotkb:pyk-1(gene name)|psi-mi:pyk-1(display_short)|uniprotkb:CELE_F25H5.3(orf name) psi-mi:q23539_caeel(display_long)|uniprotkb:pyk-2(gene name)|psi-mi:pyk-2(display_short)|uniprotkb:CELE_ZK593.1(orf name)|uniprotkb:ZK593.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456621|imex:IM-11985-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492458.1|wormbase:F25H5.3a|dip:DIP-25767N|ensemblmetazoa:F25H5.3a.1(transcript)|ensemblmetazoa:WBGene00009126(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006096"(glycolytic process)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442 wormbase:ZK593.1a|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|refseq:NP_001255515.1|reactome:R-CEL-6798695|reactome:R-CEL-70171|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918|ensemblmetazoa:WBGene00014001(gene)|ensemblmetazoa:ZK593.1a.1(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006096"(glycolytic process)|go:"GO:0016301"(kinase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030955"(potassium ion binding)|go:"GO:0055120"(striated muscle dense body) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LUf9wjXVVkAmu62ya7lOivnWkkk6239 rogid:RcZfldAHb42t/xBD07CpZMdGf8M6239 intact-crc:A71B26FF7BD3E54C|rigid:grWJT6OkRBbwIZw3xjfEAg8seyQ false - sufficient binding region:6-515("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:O76406 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-1175918|ensemblmetazoa:T10B5.6.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:o76406_caeel(display_long)|uniprotkb:knl-3(gene name)|psi-mi:knl-3(display_short)|uniprotkb:CELE_T10B5.6(orf name)|uniprotkb:T10B5.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456651|imex:IM-11985-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_503520.1|wormbase:T10B5.6|ensemblmetazoa:T10B5.6.1(transcript)|ensemblmetazoa:WBGene00020392(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1905561"(positive regulation of kinetochore assembly) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:YdVt0+9h0bkfHGwA9xNuJiWIimo6239 intact-crc:517E3EEC3FD95E0A|rigid:R0ammEZyhSa+OiRYvJf4SXLSrMo false sufficient binding region:645-774("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23539 uniprotkb:Q7JL40 intact:EBI-2003265|ensemblmetazoa:ZK593.1a.1 intact:EBI-2003280|ensemblmetazoa:F25H5.3c.1|ensemblmetazoa:F25H5.3c.2 psi-mi:q23539_caeel(display_long)|uniprotkb:pyk-2(gene name)|psi-mi:pyk-2(display_short)|uniprotkb:CELE_ZK593.1(orf name)|uniprotkb:ZK593.1(orf name) psi-mi:q7jl40_caeel(display_long)|uniprotkb:F25H5.3(orf name)|uniprotkb:pyk-1(gene name)|psi-mi:pyk-1(display_short)|uniprotkb:CELE_F25H5.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456641|imex:IM-11985-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:ZK593.1a|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|refseq:NP_001255515.1|reactome:R-CEL-6798695|reactome:R-CEL-70171|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918|ensemblmetazoa:WBGene00014001(gene)|ensemblmetazoa:ZK593.1a.1(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006096"(glycolytic process)|go:"GO:0016301"(kinase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030955"(potassium ion binding)|go:"GO:0055120"(striated muscle dense body) refseq:NP_001021411.1|wormbase:F25H5.3c|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918|ensemblmetazoa:F25H5.3c.1(transcript)|ensemblmetazoa:F25H5.3c.2(transcript)|ensemblmetazoa:WBGene00009126(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006096"(glycolytic process)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:RcZfldAHb42t/xBD07CpZMdGf8M6239 rogid:qY9iMmQxHnIJzgtfHMkwT0nCMvM6239 intact-crc:64E9CCC4B41C43E6|rigid:WWBxZtTyxZ5av1vsW6S3qpuPj1U false sufficient binding region:6-515("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17835 uniprotkb:Q23539 intact:EBI-320466|ensemblmetazoa:F25H5.3b.1 intact:EBI-2003265|ensemblmetazoa:ZK593.1a.1 psi-mi:o17835_caeel(display_long)|uniprotkb:pyk-1(gene name)|psi-mi:pyk-1(display_short)|uniprotkb:F25H5.3(orf name)|uniprotkb:CELE_F25H5.3(orf name) psi-mi:q23539_caeel(display_long)|uniprotkb:pyk-2(gene name)|psi-mi:pyk-2(display_short)|uniprotkb:CELE_ZK593.1(orf name)|uniprotkb:ZK593.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456631|imex:IM-11985-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492459.1|wormbase:F25H5.3b|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:0006096"(glycolytic process)|ensemblmetazoa:F25H5.3b.1(transcript)|ensemblmetazoa:WBGene00009126(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918|interpro:IPR040442 wormbase:ZK593.1a|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|refseq:NP_001255515.1|reactome:R-CEL-6798695|reactome:R-CEL-70171|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918|ensemblmetazoa:WBGene00014001(gene)|ensemblmetazoa:ZK593.1a.1(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006096"(glycolytic process)|go:"GO:0016301"(kinase activity)|go:"GO:0030017"(sarcomere)|go:"GO:0030955"(potassium ion binding)|go:"GO:0055120"(striated muscle dense body) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LujAWov/j9CHjyAhZ7lOpiA++IY6239 rogid:RcZfldAHb42t/xBD07CpZMdGf8M6239 intact-crc:4F8881E1C26E164F|rigid:CxneAs0ozhOYLfX4mdS269laXlA false - sufficient binding region:6-515("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95005 uniprotkb:Q09560 intact:EBI-316796|ensemblmetazoa:C36B1.4.1|ensemblmetazoa:C36B1.4.2 intact:EBI-316394|ensemblmetazoa:F36G3.1.1|ensemblmetazoa:F36G3.1.2 psi-mi:psa7_caeel(display_long)|uniprotkb:pas-4(gene name)|psi-mi:pas-4(display_short)|uniprotkb:C36B1.4(orf name)|uniprotkb:Proteasome subunit alpha 4(gene name synonym) psi-mi:yqy1_caeel(display_long)|uniprotkb:F36G3.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456661|imex:IM-11985-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5689603|reactome:R-CEL-5689880|refseq:NP_492360.1|wormbase:C36B1.4|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:C36B1.4.1(transcript)|ensemblmetazoa:C36B1.4.2(transcript)|ensemblmetazoa:WBGene00003925(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_509642.1|wormbase:F36G3.1|ensemblmetazoa:F36G3.1.1(transcript)|ensemblmetazoa:F36G3.1.2(transcript)|ensemblmetazoa:WBGene00009482(gene)|dip:DIP-27493N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WWXt5jeuKRCX9WomT3Wqk45PRIc6239 rogid:37oYxe8ZMYfNgmwEx7RUcIR3nAw6239 intact-crc:E7B1F8AD47031C5A|rigid:gYvhkcJ7rCdUB+x+DkMRHvflnd8 false - sufficient binding region:643-964("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2S6 uniprotkb:P91175 intact:EBI-2002562|ensemblmetazoa:Y116A8C.34a.1|ensemblmetazoa:Y116A8C.34a.2 intact:EBI-2415020|ensemblmetazoa:C50F2.3.1 psi-mi:q9u2s6_caeel(display_long)|uniprotkb:cyn-13(gene name)|psi-mi:cyn-13(display_short)|uniprotkb:CELE_Y116A8C.34(orf name)|uniprotkb:Y116A8C.34(orf name) psi-mi:p91175_caeel(display_long)|uniprotkb:syf-1(gene name)|psi-mi:syf-1(display_short)|uniprotkb:C50F2.3(orf name)|uniprotkb:CELE_C50F2.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456706|imex:IM-11985-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y116A8C.34a|interpro:IPR020892|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001255925.1|interpro:IPR034168|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-6798695|reactome:R-CEL-72163|interpro:IPR029000|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:WBGene00000889(gene)|ensemblmetazoa:Y116A8C.34a.1(transcript)|ensemblmetazoa:Y116A8C.34a.2(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding) refseq:NP_491250.1|wormbase:C50F2.3|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-72163|ensemblmetazoa:C50F2.3.1(transcript)|ensemblmetazoa:WBGene00016837(gene)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WJWGjueqBvYodqE61PXj1P+oICg6239 rogid:TJCW0aRExDbLbOr1D0eUTR8CTO86239 intact-crc:B9DAC6B37867D801|rigid:+eCrxocNO57d6qKrnpTuE48YlwI false sufficient binding region:6-331("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16297 uniprotkb:Q9XVR7 intact:EBI-2001978|ensemblmetazoa:F32D1.10.1 intact:EBI-318007|ensemblmetazoa:C25D7.6.1 psi-mi:o16297_caeel(display_long)|uniprotkb:MCM7(gene name synonym)|uniprotkb:CELE_F32D1.10(orf name)|uniprotkb:F32D1.10(orf name)|uniprotkb:mcm-7(gene name)|psi-mi:mcm-7(display_short) psi-mi:q9xvr7_caeel(display_long)|uniprotkb:mcm-3(gene name)|psi-mi:mcm-3(display_short)|uniprotkb:C25D7.6(orf name)|uniprotkb:CELE_C25D7.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456681|imex:IM-11985-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504199.1|wormbase:F32D1.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|interpro:IPR033762|reactome:R-CEL-69052|reactome:R-CEL-68949|interpro:IPR027417|interpro:IPR027925|reactome:R-CEL-176187|interpro:IPR041562|reactome:R-CEL-68962|ensemblmetazoa:F32D1.10.1(transcript)|ensemblmetazoa:WBGene00003159(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0042555"(MCM complex)|go:"GO:0072689"(MCM complex assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity) refseq:NP_506706.1|wormbase:C25D7.6|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0045120"(pronucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|ensemblmetazoa:C25D7.6.1(transcript)|ensemblmetazoa:WBGene00003155(gene)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-27417N|reactome:R-CEL-176187|reactome:R-CEL-69052|reactome:R-CEL-68962|reactome:R-CEL-68949 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:9dqqgCZyTEtUWKwBDmXDCgX6Ko86239 rogid:UWz3c+ZT3842l3k9yzTMzKo2Q/w6239 intact-crc:8FDF379F8D68834D|rigid:EK1oVXE2fq31BPoYLSNcP5IFN74 false sufficient binding region:63-730("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09560 uniprotkb:Q95ZQ3 intact:EBI-316394|ensemblmetazoa:F36G3.1.1|ensemblmetazoa:F36G3.1.2 intact:EBI-2004972|ensemblmetazoa:T02G5.9b.1 psi-mi:yqy1_caeel(display_long)|uniprotkb:F36G3.1(orf name) psi-mi:q95zq3_caeel(display_long)|uniprotkb:kars-1(gene name)|psi-mi:kars-1(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:CELE_T02G5.9(orf name)|uniprotkb:T02G5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456671|imex:IM-11985-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509642.1|wormbase:F36G3.1|ensemblmetazoa:F36G3.1.1(transcript)|ensemblmetazoa:F36G3.1.2(transcript)|ensemblmetazoa:WBGene00009482(gene)|dip:DIP-27493N refseq:NP_495454.1|wormbase:T02G5.9b|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR044136|ensemblmetazoa:T02G5.9b.1(transcript)|ensemblmetazoa:WBGene00002238(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006430"(lysyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:37oYxe8ZMYfNgmwEx7RUcIR3nAw6239 rogid:iQvw4aeBips00raW7AoVlOjdpXU6239 intact-crc:4436AF2345024896|rigid:+hBKZp55thxmMjzl4x01/NRofNw false sufficient binding region:643-964("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09293 uniprotkb:O61955-1 intact:EBI-2001908|uniprotkb:Q9BMU5|ensemblmetazoa:EEED8.1.1|ensemblmetazoa:EEED8.1.2 intact:EBI-6456691|ensemblmetazoa:B0348.6b.1|ensemblmetazoa:B0348.6b.2 psi-mi:tofu6_caeel(display_long)|uniprotkb:tofu-6(gene name)|psi-mi:tofu-6(display_short)|uniprotkb:21U-RNA biogenesis fouled up protein 6(gene name synonym)|uniprotkb:Maternal effect lethal protein 47(gene name synonym)|uniprotkb:mel-47(gene name synonym)|uniprotkb:EEED8.1(orf name) psi-mi:o61955-1(display_long)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:B0348.6(orf name)|uniprotkb:ife-3(gene name)|psi-mi:ife-3(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456696|imex:IM-11985-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:EEED8.1|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001293507.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:EEED8.1.1(transcript)|ensemblmetazoa:EEED8.1.2(transcript)|ensemblmetazoa:WBGene00017132(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:1990511"(piRNA biosynthetic process) intact:EBI-330119(isoform-parent)|ensemblmetazoa:B0348.6b.1(transcript)|ensemblmetazoa:B0348.6b.2(transcript)|ensemblmetazoa:WBGene00002061(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Cm2HAo45aqy6PjSygRlS40QKsr46239 rogid:444BHWm5Eiqg+MUqKRgLhbVaxUo6239 intact-crc:6454C248043747A2|rigid:rt31Wsun8d2QBY8Swkct8BDQybI false sufficient binding region:63-367("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19130 uniprotkb:P34509 intact:EBI-331451|ensemblmetazoa:F07A11.2a.1|ensemblmetazoa:F07A11.2a.2|ensemblmetazoa:F07A11.2a.3|ensemblmetazoa:F07A11.2a.4 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 psi-mi:q19130_caeel(display_long)|uniprotkb:gfat-1(gene name)|psi-mi:gfat-1(display_short)|uniprotkb:CELE_F07A11.2(orf name)|uniprotkb:F07A11.2(orf name) psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456731|imex:IM-11985-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-446210|refseq:NP_496480.1|wormbase:F07A11.2a|dip:DIP-26050N|ensemblmetazoa:F07A11.2a.1(transcript)|ensemblmetazoa:F07A11.2a.2(transcript)|ensemblmetazoa:F07A11.2a.3(transcript)|ensemblmetazoa:F07A11.2a.4(transcript)|ensemblmetazoa:WBGene00008546(gene)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490 refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:EXxUvmcQTTl6qV61gXGgFNAZHAo6239 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 intact-crc:65CECDB702A942B8|rigid:teDqVfBSSFW8OTAE/B7YjopzWY8 false sufficient binding region:61-725("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19130 uniprotkb:O45926 intact:EBI-331451|ensemblmetazoa:F07A11.2a.1|ensemblmetazoa:F07A11.2a.2|ensemblmetazoa:F07A11.2a.3|ensemblmetazoa:F07A11.2a.4 intact:EBI-330800|ensemblmetazoa:Y43E12A.1.1 psi-mi:q19130_caeel(display_long)|uniprotkb:gfat-1(gene name)|psi-mi:gfat-1(display_short)|uniprotkb:CELE_F07A11.2(orf name)|uniprotkb:F07A11.2(orf name) psi-mi:o45926_caeel(display_long)|uniprotkb:cyb-2.1(gene name)|psi-mi:cyb-2.1(display_short)|uniprotkb:Y43E12A.1(orf name)|uniprotkb:CELE_Y43E12A.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456741|imex:IM-11985-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-446210|refseq:NP_496480.1|wormbase:F07A11.2a|dip:DIP-26050N|ensemblmetazoa:F07A11.2a.1(transcript)|ensemblmetazoa:F07A11.2a.2(transcript)|ensemblmetazoa:F07A11.2a.3(transcript)|ensemblmetazoa:F07A11.2a.4(transcript)|ensemblmetazoa:WBGene00008546(gene)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490 refseq:NP_502047.1|wormbase:Y43E12A.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|reactome:R-CEL-176408|reactome:R-CEL-2500257|reactome:R-CEL-6804114|reactome:R-CEL-69273|reactome:R-CEL-69478|interpro:IPR039361|interpro:IPR036915|go:"GO:0044772"(mitotic cell cycle phase transition)|ensemblmetazoa:WBGene00000866(gene)|ensemblmetazoa:Y43E12A.1.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|reactome:R-CEL-2565942|reactome:R-CEL-4419969|reactome:R-CEL-8878166|reactome:R-CEL-2299718 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:EXxUvmcQTTl6qV61gXGgFNAZHAo6239 rogid:3utXAZnYQvOH6Y+iPVRSIB8dqPw6239 intact-crc:74277DC5D91406CF|rigid:KcbnOIgMqhCN4Vk7dj1op0Cvgfo false sufficient binding region:61-725("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01576 uniprotkb:Q21295 intact:EBI-318147|ensemblmetazoa:F53F10.5.1|ensemblmetazoa:F53F10.5.2 intact:EBI-2004307|uniprotkb:Q21296|ensemblmetazoa:K07F5.13a.1 psi-mi:o01576_caeel(display_long)|uniprotkb:npp-11(gene name)|psi-mi:npp-11(display_short)|uniprotkb:F53F10.5(orf name)|uniprotkb:CELE_F53F10.5(orf name) psi-mi:q21295_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456751|imex:IM-11985-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F53F10.5|refseq:NP_491232.1|ensemblmetazoa:F53F10.5.1(transcript)|ensemblmetazoa:F53F10.5.2(transcript)|ensemblmetazoa:WBGene00003797(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25053N refseq:NP_501772.1|wormbase:K07F5.13a|interpro:IPR024864|interpro:IPR025712|ensemblmetazoa:K07F5.13a.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:MI7h0vaxVjYQ8SIw1bMVdk5rCl06239 rogid:CgqZPl+7gsTQJxOMbCCLLuEiUh46239 intact-crc:0BFB76703775A85F|rigid:ffhAIWeelSw8PBhjTHHOYbXTENs false sufficient binding region:604-731("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86S28 uniprotkb:P90916 intact:EBI-6456716|ensemblmetazoa:T27C4.4d.1 intact:EBI-324314|uniprotkb:A2JDY3|uniprotkb:O62411|ensemblmetazoa:K07A1.12.1 psi-mi:q86s28_caeel(display_long)|uniprotkb:T27C4.4(orf name)|uniprotkb:lin-40(gene name)|psi-mi:lin-40(display_short)|uniprotkb:CELE_T27C4.4(orf name) psi-mi:lin53_caeel(display_long)|uniprotkb:lin-53(gene name)|psi-mi:lin-53(display_short)|uniprotkb:rba-2(gene name synonym)|uniprotkb:K07A1.12(orf name)|uniprotkb:Abnormal cell lineage protein 53(gene name synonym)|uniprotkb:Synthetic multivulva protein p48(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456721|imex:IM-11985-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T27C4.4d.1(transcript)|ensemblmetazoa:WBGene00003025(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR040138|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|refseq:NP_872124.1|wormbase:T27C4.4d|interpro:IPR043151 refseq:NP_492552.1|wormbase:K07A1.12|reactome:R-CEL-2559580|reactome:R-CEL-3214858|ensemblmetazoa:K07A1.12.1(transcript)|ensemblmetazoa:WBGene00003036(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0070176"(DRM complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|reactome:R-CEL-3214847|dip:DIP-24440N|reactome:R-CEL-8951664|reactome:R-CEL-8943724|reactome:R-CEL-1538133|reactome:R-CEL-212300|reactome:R-CEL-3214815|reactome:R-CEL-8953750 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XQSbrHibBD6liMLx0WK299rOARk6239 rogid:v5/7m30zbtMyaxt8xomuotdJqcA6239 intact-crc:006C9FDE49DB4246|rigid:4rsz/zG6mA/u0HnVgpArd6SIEaE false sufficient binding region:630-870("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09543 uniprotkb:Q9GZH6 intact:EBI-322806|ensemblmetazoa:F48E8.5.1|ensemblmetazoa:F48E8.5.2 intact:EBI-2003817|ensemblmetazoa:T22D1.5.1 psi-mi:2aaa_caeel(display_long)|uniprotkb:F48E8.5(orf name)|uniprotkb:Protein phosphatase PP2A regulatory subunit A(gene name synonym)|uniprotkb:paa-1(gene name)|psi-mi:paa-1(display_short) psi-mi:q9gzh6_caeel(display_long)|uniprotkb:T22D1.5(orf name)|uniprotkb:CELE_T22D1.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456791|imex:IM-11985-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498162.2|wormbase:F48E8.5|reactome:R-CEL-69231|reactome:R-CEL-198753|reactome:R-CEL-202670|reactome:R-CEL-2995383|reactome:R-CEL-69273|ensemblmetazoa:F48E8.5.1(transcript)|ensemblmetazoa:F48E8.5.2(transcript)|ensemblmetazoa:WBGene00003901(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043186"(P granule)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|reactome:R-CEL-195253|dip:DIP-26927N|reactome:R-CEL-196299|reactome:R-CEL-975957|reactome:R-CEL-5673000|reactome:R-CEL-5675221|reactome:R-CEL-389513|reactome:R-CEL-6811558 refseq:NP_501063.1|wormbase:T22D1.5|interpro:IPR011992(EF-Hand type)|ensemblmetazoa:T22D1.5.1(transcript)|ensemblmetazoa:WBGene00020684(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:9aApJ05VzQgGuaJ65kMPqQRBEb06239 rogid:CLKPg/U4RH1rurftm+JSLnau00g6239 intact-crc:F966AE94BABD42F1|rigid:B25sFRYp+3HsoQJMeufchXmO0aM false - sufficient binding region:60-391("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30642 uniprotkb:O61708 intact:EBI-311981|ensemblmetazoa:R08D7.3.1 intact:EBI-315255|ensemblmetazoa:R119.4.1 psi-mi:eif3d_caeel(display_long)|uniprotkb:R08D7.3(orf name)|uniprotkb:eif-3.D(gene name)|psi-mi:eif-3.D(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym) psi-mi:o61708_caeel(display_long)|uniprotkb:pqn-59(gene name)|psi-mi:pqn-59(display_short)|uniprotkb:CELE_R119.4(orf name)|uniprotkb:R119.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456771|imex:IM-11985-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72649|ensemblmetazoa:R08D7.3.1(transcript)|ensemblmetazoa:WBGene00001227(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|refseq:NP_498984.1|wormbase:R08D7.3|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|dip:DIP-25819N refseq:NP_490727.1|wormbase:R119.4|ensemblmetazoa:R119.4.1(transcript)|ensemblmetazoa:WBGene00004143(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR009060(UBA-like)|dip:DIP-25020N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CvW4IPXX62lvTWXOvGSZttuD3cs6239 rogid:K83JJthOIli1KrkmuKJbMtYpX7I6239 intact-crc:2F0640EF0A3DAA94|rigid:tjhFK/UDiAoe5AbHgnsUttkmbIw false - sufficient binding region:604-712("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01576 uniprotkb:Q9U3C1 intact:EBI-318147|ensemblmetazoa:F53F10.5.1|ensemblmetazoa:F53F10.5.2 intact:EBI-2004353|ensemblmetazoa:K07F5.13b.1 psi-mi:o01576_caeel(display_long)|uniprotkb:npp-11(gene name)|psi-mi:npp-11(display_short)|uniprotkb:F53F10.5(orf name)|uniprotkb:CELE_F53F10.5(orf name) psi-mi:q9u3c1_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456761|imex:IM-11985-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F53F10.5|refseq:NP_491232.1|ensemblmetazoa:F53F10.5.1(transcript)|ensemblmetazoa:F53F10.5.2(transcript)|ensemblmetazoa:WBGene00003797(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25053N refseq:NP_501771.1|wormbase:K07F5.13b|interpro:IPR024864|interpro:IPR025712|interpro:IPR025574|ensemblmetazoa:K07F5.13b.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:MI7h0vaxVjYQ8SIw1bMVdk5rCl06239 rogid:PBUFj0HXUAAcVEWkwfLNogGoZNQ6239 intact-crc:553BC1AD33011475|rigid:6I21QUKnWD253BPNHE85/ZybchI false sufficient binding region:604-731("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44144 uniprotkb:Q21735 intact:EBI-319794|ensemblmetazoa:C44B12.5.1 intact:EBI-2004567|ensemblmetazoa:R05D11.3.1 psi-mi:o44144_caeel(display_long)|uniprotkb:perm-4(gene name)|psi-mi:perm-4(display_short)|uniprotkb:C44B12.5(orf name)|uniprotkb:CELE_C44B12.5(orf name) psi-mi:ntf2_caeel(display_long)|uniprotkb:ran-4(gene name)|psi-mi:ran-4(display_short)|uniprotkb:R05D11.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456781|imex:IM-11985-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C44B12.5|ensemblmetazoa:C44B12.5.1(transcript)|ensemblmetazoa:WBGene00016638(gene)|refseq:NP_500041.2|dip:DIP-26823N refseq:NP_492322.1|wormbase:R05D11.3|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|ensemblmetazoa:R05D11.3.1(transcript)|ensemblmetazoa:WBGene00004305(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0044613"(nuclear pore central transport channel) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:MSVIEajq6XpoEVL4RehbFBS4z6c6239 rogid:MO3nF45y4Qnv1bnk707RFa3N6hU6239 intact-crc:CDEC96ABA21F7EB8|rigid:3FlmIafboMnl3puA3Z2egvcxSo4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22798 uniprotkb:Q9U3C8 intact:EBI-2005444|ensemblmetazoa:T26A5.8.1 intact:EBI-323766|uniprotkb:Q9U3C9|ensemblmetazoa:H38K22.2a.1 psi-mi:q22798_caeel(display_long)|uniprotkb:CELE_T26A5.8(orf name)|uniprotkb:T26A5.8(orf name) psi-mi:dcn1_caeel(display_long)|uniprotkb:dcn-1(gene name)|psi-mi:dcn-1(display_short)|uniprotkb:H38K22.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456831|imex:IM-11985-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498421.1|wormbase:T26A5.8|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-CEL-110314|reactome:R-CEL-5651801|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-68952|reactome:R-CEL-68962|ensemblmetazoa:T26A5.8.1(transcript)|ensemblmetazoa:WBGene00020823(gene)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_497866.2|refseq:NP_497867.2|wormbase:H38K22.2a|wormbase:H38K22.2b|interpro:IPR014764(Defective in cullin neddylation)|interpro:IPR005176(Protein of unknown function DUF298)|interpro:IPR009060(UBA-like)|ensemblmetazoa:H38K22.2a.1(transcript)|ensemblmetazoa:WBGene00010428(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032182"(ubiquitin-like protein binding)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0097602"(cullin family protein binding)|reactome:R-CEL-8951664|interpro:IPR042460 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:VFOXgR2bz3rlMgUZQp2wn0cGSqE6239 rogid:X+LaD4EiIe/k1JZ2eCvPnfrGc0g6239 intact-crc:D7B4755F3F30CF23|rigid:/Q4k1JdW0MNWKJZ8U9iS4Tq9N5o false - sufficient binding region:60-193("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WT44 uniprotkb:P90868 intact:EBI-2002025|uniprotkb:G5EDU8|ensemblmetazoa:ZK328.1b.1 intact:EBI-317074|ensemblmetazoa:F39H11.5.1 psi-mi:ubph_caeel(display_long)|uniprotkb:CeUBP130(gene name synonym)|uniprotkb:Cytokinesis defective protein 3(gene name synonym)|uniprotkb:uch-1(gene name synonym)|uniprotkb:ZK328.1(orf name)|uniprotkb:cyk-3(gene name)|psi-mi:cyk-3(display_short) psi-mi:p90868_caeel(display_long)|uniprotkb:pbs-7(gene name)|psi-mi:pbs-7(display_short)|uniprotkb:F39H11.5(orf name)|uniprotkb:CELE_F39H11.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456801|imex:IM-11985-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022992.1|wormbase:ZK328.1b|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|refseq:NP_498311.2|interpro:IPR035927|interpro:IPR038765|wormbase:ZK328.1a|reactome:R-CEL-5689880|ensemblmetazoa:WBGene00000874(gene)|ensemblmetazoa:ZK328.1b.1(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904785"(regulation of asymmetric protein localization involved in cell fate determination)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization) reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_492354.1|wormbase:F39H11.5|ensemblmetazoa:F39H11.5.1(transcript)|ensemblmetazoa:WBGene00003953(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR029055|reactome:R-CEL-5632684|reactome:R-CEL-8932339|dip:DIP-26967N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LbOi5WL6TFO24ZC3+KhxtzJ/8ZY6239 rogid:b0ur9kPZL37Eqp8qt6e41061Zc06239 intact-crc:72363B372725DDE0|rigid:VxSfoQDuTga9+c8Kab1LDejZrb8 false sufficient binding region:603-1072("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01585 uniprotkb:G5ECG0 intact:EBI-2004403|ensemblmetazoa:K09H11.3.1 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:o01585_caeel(display_long)|uniprotkb:CELE_K09H11.3(orf name)|uniprotkb:rga-3(gene name)|psi-mi:rga-3(display_short)|uniprotkb:K09H11.3(orf name) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456821|imex:IM-11985-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504503.1|wormbase:K09H11.3|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR042869|ensemblmetazoa:K09H11.3.1(transcript)|ensemblmetazoa:WBGene00019600(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OmLo3eyH9KRRr+1RpDnLNNzl2Zs6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:76369C2286E46E8D|rigid:THSWosbauapbf4Ac+u9HxXBHl6Q false - sufficient binding region:60-260("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19749 uniprotkb:G5ECG0 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456811|imex:IM-11985-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:9776705A21908194|rigid:+YWUDVKUMblU7T7/kb6gZYdvml8 false - sufficient binding region:60-260("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34509 uniprotkb:P34342-1 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 intact:EBI-6456879|ensemblmetazoa:C29E4.3a.1 psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:p34342-1(display_long)|uniprotkb:RanGAP(gene name synonym)|uniprotkb:C29E4.3(orf name)|uniprotkb:Ran nuclear import/export-related protein 2(gene name synonym)|uniprotkb:ran-2(gene name)|psi-mi:ran-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456876|imex:IM-11985-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) ensemblmetazoa:C29E4.3a.1(transcript)|ensemblmetazoa:WBGene00004303(gene)|intact:EBI-6499769(isoform-parent) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 rogid:1uQylfSmaggjWNAEbOKcvb6nj/c6239 intact-crc:FFC7395BF5AAC644|rigid:8tscL1GK+GSOLilHtyF6xPgk/E0 false sufficient binding region:59-166("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23179 uniprotkb:Q2V0X4 intact:EBI-327224|ensemblmetazoa:W05H9.1a.1 intact:EBI-6456854 psi-mi:q23179_caeel(display_long)|uniprotkb:W05H9.1(orf name)|uniprotkb:CELE_W05H9.1(orf name) psi-mi:q2v0x4_caeel(display_long)|uniprotkb:cogc-3(gene name)|psi-mi:cogc-3(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456851|imex:IM-11985-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509050.1|wormbase:W05H9.1a|ensemblmetazoa:W05H9.1a.1(transcript)|ensemblmetazoa:WBGene00021048(gene)|go:"GO:0016021"(integral component of membrane)|mint:Q23179|dip:DIP-25576N go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007265(Sec34-like protein) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0UrY5KcZbO+e3veSNe2PthHeeaI6239 rogid:G/tGsp4WwyIUGdFnfOzoBMkgOrM6239 intact-crc:F9327A22F3101ED8|rigid:vSxDLTwvGb7ngcFzZqe5ORfg23w false sufficient binding region:59-414("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22799 uniprotkb:O45599 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 intact:EBI-319105|ensemblmetazoa:H02I12.1.1 psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:cbd1_caeel(display_long)|uniprotkb:cbd-1(gene name)|psi-mi:cbd-1(display_short)|uniprotkb:H02I12.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456841|imex:IM-11985-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 refseq:NP_502145.2|wormbase:H02I12.1|ensemblmetazoa:H02I12.1.1(transcript)|ensemblmetazoa:WBGene00010351(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|go:"GO:0030703"(eggshell formation)|go:"GO:0071944"(cell periphery)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|dip:DIP-26633N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 rogid:D0mH3+/FTIlBGARvBXqMOF4FHbE6239 intact-crc:78C986CED4C42020|rigid:XJ4jdUFxOt+WZrRJuTuErUkocl8 false - sufficient binding region:597-1319("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34509 uniprotkb:Q23670 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 intact:EBI-323996|uniprotkb:Q27509|ensemblmetazoa:K12D12.1.1 psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:top2_caeel(display_long)|uniprotkb:top-2(gene name)|psi-mi:top-2(display_short)|uniprotkb:DNA topoisomerase II(gene name synonym)|uniprotkb:K12D12.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456866|imex:IM-11985-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) refseq:NP_496536.1|wormbase:K12D12.1|ensemblmetazoa:K12D12.1.1(transcript)|ensemblmetazoa:WBGene00010785(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006265"(DNA topological change)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR034157|interpro:IPR036890|interpro:IPR031660|reactome:R-CEL-4615885|dip:DIP-27416N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 rogid:mMVe6/tBKCkNlRfJ3X08lsDKthg6239 intact-crc:923C74020A758A38|rigid:Dn92OkDUNP4hR8Ba0Emx3j88BQg false sufficient binding region:59-267("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:P55853 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456907|imex:IM-11985-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:0D037357A8CB2980|rigid:+XhWuNrbf1k9eSRivYfRY9n19E0 false sufficient binding region:5-91("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94420 uniprotkb:P55853 intact:EBI-320790|uniprotkb:Q94139|ensemblmetazoa:ZK858.4a.1 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:mel26_caeel(display_long)|uniprotkb:ZK858.4(orf name)|uniprotkb:mel-26(gene name)|psi-mi:mel-26(display_short) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456927|imex:IM-11985-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492449.2|wormbase:ZK858.4a|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|ensemblmetazoa:WBGene00003209(gene)|ensemblmetazoa:ZK858.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031674"(I band)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-27179N|reactome:R-CEL-5632684 reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LdD7Fd/bItR1N1LukujfPZi0MqI6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:537D74086855D245|rigid:paO4wmmNRPlCK23OVJcME8YbwxE false - sufficient binding region:5-91("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:Q17353-1 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-6456891|ensemblmetazoa:F54E7.3b.1|ensemblmetazoa:F54E7.3b.2 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:q17353-1(display_long)|uniprotkb:Abnormal embryonic partitioning of cytoplasm protein 3(gene name synonym)|uniprotkb:F54E7.3(orf name)|uniprotkb:par-3(gene name)|psi-mi:par-3(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456897|imex:IM-11985-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 ensemblmetazoa:F54E7.3b.1(transcript)|ensemblmetazoa:F54E7.3b.2(transcript)|ensemblmetazoa:WBGene00003918(gene)|intact:EBI-321762(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:tg0WlCFGzovNQANMPpSWW1riAAY6239 intact-crc:6F8716ED95E8DD26|rigid:FguPNr/UwfQouW4g6BfPzO/C5Yk false sufficient binding region:5-91("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:Q9XVU8 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456917|imex:IM-11985-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:70BA5A9B08A5E748|rigid:3S51uMCXDnausUUU1D7te7xp20o false sufficient binding region:5-91("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30642 uniprotkb:Q22799 intact:EBI-311981|ensemblmetazoa:R08D7.3.1 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:eif3d_caeel(display_long)|uniprotkb:R08D7.3(orf name)|uniprotkb:eif-3.D(gene name)|psi-mi:eif-3.D(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456967|imex:IM-11985-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72649|ensemblmetazoa:R08D7.3.1(transcript)|ensemblmetazoa:WBGene00001227(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|refseq:NP_498984.1|wormbase:R08D7.3|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|dip:DIP-25819N refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CvW4IPXX62lvTWXOvGSZttuD3cs6239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:C46FC6E6CF0AEC3B|rigid:PX1zPtB3W8PcHNi5zJ9za1/LXdE false - sufficient binding region:5-89("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XTU6 uniprotkb:Q9N4G9 intact:EBI-330975|ensemblmetazoa:Y49E10.15.1 intact:EBI-2411974|ensemblmetazoa:Y71F9B.4.1 psi-mi:ruxe_caeel(display_long)|uniprotkb:snr-6(gene name)|psi-mi:snr-6(display_short)|uniprotkb:Y49E10.15(orf name)|uniprotkb:Sm protein E(gene name synonym) psi-mi:ruxg_caeel(display_long)|uniprotkb:Y71F9B.4(orf name)|uniprotkb:snr-7(gene name)|psi-mi:snr-7(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456937|imex:IM-11985-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499620.1|wormbase:Y49E10.15|reactome:R-CEL-72163|reactome:R-CEL-72165|dip:DIP-24866N|ensemblmetazoa:WBGene00004919(gene)|ensemblmetazoa:Y49E10.15.1(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0043186"(P granule)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|reactome:R-CEL-111367|reactome:R-CEL-191859|reactome:R-CEL-73856|reactome:R-CEL-77588 refseq:NP_491032.1|wormbase:Y71F9B.4|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|reactome:R-CEL-72163|reactome:R-CEL-72165|interpro:IPR034098|reactome:R-CEL-111367|reactome:R-CEL-191859|reactome:R-CEL-73856|reactome:R-CEL-77588|interpro:IPR044641|ensemblmetazoa:WBGene00004920(gene)|ensemblmetazoa:Y71F9B.4.1(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043186"(P granule)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b9dK8vRJrMwefCpta28kv+7RgkM6239 rogid:NBc301PkpVImlVz5VuQ9cLa2vQY6239 intact-crc:F432608BC4C6FB3D|rigid:WlKZ2//9t56T8Va8q/G8gkznqPc false sufficient binding region:5-90("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18194 uniprotkb:Q22799 intact:EBI-2002421|ensemblmetazoa:C26B2.1.1 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:q18194_caeel(display_long)|uniprotkb:dnc-4(gene name)|psi-mi:dnc-4(display_short)|uniprotkb:CELE_C26B2.1(orf name)|uniprotkb:C26B2.1(orf name) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456947|imex:IM-11985-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501344.1|wormbase:C26B2.1|interpro:IPR008603(Dynactin p62)|reactome:R-CEL-6811436|reactome:R-CEL-3371497|reactome:R-CEL-6807878|ensemblmetazoa:C26B2.1.1(transcript)|ensemblmetazoa:WBGene00016124(gene)|go:"GO:0005869"(dynactin complex) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XgXybdcDeIC6UEGYvvS5eSemoiE6239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:7BFCFC3949B29DD8|rigid:w1ctB2yNojcUSHgW06vZlV52Q0U false - sufficient binding region:5-89("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46502 uniprotkb:Q22799 intact:EBI-312846|ensemblmetazoa:F23F12.6.1|ensemblmetazoa:F23F12.6.2 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:prs6b_caeel(display_long)|uniprotkb:F23F12.6(orf name)|uniprotkb:rpt-3(gene name)|psi-mi:rpt-3(display_short) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456957|imex:IM-11985-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498429.1|wormbase:F23F12.6|reactome:R-CEL-8932339|ensemblmetazoa:F23F12.6.1(transcript)|ensemblmetazoa:F23F12.6.2(transcript)|ensemblmetazoa:WBGene00004503(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|reactome:R-CEL-5632684|dip:DIP-24412N|reactome:R-CEL-68949|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:DhM99pdwdpe4k+W2+mURYee+T/Q6239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:8C1309BDCA488541|rigid:7dgK01xfxJ64tBJvm3ra7ZY2PMA false - sufficient binding region:5-89("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45935 uniprotkb:Q18282 intact:EBI-330817|ensemblmetazoa:Y43F4B.6.1 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 psi-mi:o45935_caeel(display_long)|uniprotkb:klp-19(gene name)|psi-mi:klp-19(display_short)|uniprotkb:Y43F4B.6(orf name)|uniprotkb:CELE_Y43F4B.6(orf name) psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457007|imex:IM-11985-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499742.1|wormbase:Y43F4B.6|dip:DIP-24548N|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|ensemblmetazoa:WBGene00002229(gene)|ensemblmetazoa:Y43F4B.6.1(transcript) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0EfxMO51oKtHwI6M887Ixy/1dho6239 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 intact-crc:FDD7F6795F00C479|rigid:imbpalNf2ZHd0UfPNeto71qMKYM false sufficient binding region:574-738("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22799 uniprotkb:Q22799 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456977|imex:IM-11985-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:D31592D9474DBC2E|rigid:94YmunXzdvSvdP7I2fZiniBHwT4 false - sufficient binding region:5-89("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFV3 uniprotkb:Q22799 intact:EBI-1187461|intact:EBI-1187509|uniprotkb:G5EDA1|ensemblmetazoa:Y48A6B.11b.1 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:rsa2_caeel(display_long)|uniprotkb:Y48A6B.11(orf name)|uniprotkb:rsa-2(gene name)|psi-mi:rsa-2(display_short) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456987|imex:IM-11985-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7YSJ2(uniprot-removed-ac)|refseq:NP_001022887.1|wormbase:Y48A6B.11b|wormbase:Y48A6B.11a|refseq:NP_001022886.1|ensemblmetazoa:WBGene00012972(gene)|ensemblmetazoa:Y48A6B.11b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0048566"(embryonic digestive tract development) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2016/09/27 rogid:7PBwPJFROCL8Mv1INcviVzZGFCE6239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:1E4AB7A808A3B593|rigid:wSpli7xmYxzLC69Kaf09hmfoqVk false - sufficient binding region:5-89("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49197 uniprotkb:P46769 intact:EBI-313268|ensemblmetazoa:F37C12.11.1 intact:EBI-313262|ensemblmetazoa:B0393.1.1|ensemblmetazoa:B0393.1.2 psi-mi:rs21_caeel(display_long)|uniprotkb:rps-21(gene name)|psi-mi:rps-21(display_short)|uniprotkb:F37C12.11(orf name) psi-mi:rssa_caeel(display_long)|uniprotkb:B0393.1(orf name)|uniprotkb:rps-0(gene name)|psi-mi:rps-0(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6456997|imex:IM-11985-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498579.2|wormbase:F37C12.11|ensemblmetazoa:F37C12.11.1(transcript)|ensemblmetazoa:WBGene00004490(gene)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000461"("endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR001931(Ribosomal protein S21e)|interpro:IPR018279|interpro:IPR038579|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975957|reactome:R-CEL-72649|reactome:R-CEL-975956|dip:DIP-25541N refseq:NP_497978.1|wormbase:B0393.1|ensemblmetazoa:B0393.1.1(transcript)|ensemblmetazoa:B0393.1.2(transcript)|ensemblmetazoa:WBGene00004469(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975957|reactome:R-CEL-72649|reactome:R-CEL-975956|dip:DIP-26217N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ohoHPIQSeNMf2So+gKPi8ohMWSI6239 rogid:7tsgt7UcrNPsyTZQBzoRlcA/hvw6239 intact-crc:70194A21DF4E6C0F|rigid:psK3DEGNRSU+WwFnxYiuNcEmMMs false sufficient binding region:5-88("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01488 uniprotkb:E2JKZ0 intact:EBI-320537|ensemblmetazoa:C13F10.2.1 intact:EBI-6457030|ensemblmetazoa:ZK593.5b.1 psi-mi:o01488_caeel(display_long)|uniprotkb:kxd-1(gene name)|psi-mi:kxd-1(display_short)|uniprotkb:C13F10.2(orf name)|uniprotkb:CELE_C13F10.2(orf name) psi-mi:e2jkz0_caeel(display_long)|uniprotkb:ZK593.5(orf name)|uniprotkb:dnc-1(gene name)|psi-mi:dnc-1(display_short)|uniprotkb:CELE_ZK593.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457053|imex:IM-11985-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504831.1|wormbase:C13F10.2|ensemblmetazoa:C13F10.2.1(transcript)|ensemblmetazoa:WBGene00015742(gene)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|dip:DIP-27148N ensemblmetazoa:WBGene00001017(gene)|ensemblmetazoa:ZK593.5b.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005869"(dynactin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035047"(centrosomal and pronuclear rotation)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0035046"(pronuclear migration)|reactome:R-CEL-3371497|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|refseq:NP_001255521.1|wormbase:ZK593.5b|interpro:IPR036859|reactome:R-CEL-6807878|reactome:R-CEL-6811436 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZX/rck9tSHblPGJKegKAjZiqxeA6239 rogid:rgH3mdKlbsoIrE4c92pnEVoEjQQ6239 intact-crc:A9CB302A592EDF43|rigid:72nA8iA5yXsOQChDBkpZgj5m6Ok false - sufficient binding region:562-629("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93572 uniprotkb:P91913 intact:EBI-319283|ensemblmetazoa:F25H2.10.1 intact:EBI-316877|uniprotkb:Q9GR59|ensemblmetazoa:Y37E3.7.3|ensemblmetazoa:Y37E3.7.2|ensemblmetazoa:Y37E3.7.1 psi-mi:rla0_caeel(display_long)|uniprotkb:rla-0(gene name)|psi-mi:rla-0(display_short)|uniprotkb:rpa-0(gene name synonym)|uniprotkb:F25H2.10(orf name) psi-mi:rla1_caeel(display_long)|uniprotkb:rla-1(gene name)|psi-mi:rla-1(display_short)|uniprotkb:Y37E3.7(orf name)|uniprotkb:rpa-1(gene name synonym)|uniprotkb:Ribosomal protein large subunit P1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457017|imex:IM-11985-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492766.1|wormbase:F25H2.10|ensemblmetazoa:F25H2.10.1(transcript)|ensemblmetazoa:WBGene00004408(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|go:"GO:0070180"(large ribosomal subunit rRNA binding)|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-975957|reactome:R-CEL-975956|reactome:R-CEL-72706|dip:DIP-26018N interpro:IPR027534|refseq:NP_740801.1|wormbase:Y37E3.7|interpro:IPR001859(Ribosomal protein P2)|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-975957|reactome:R-CEL-72706|interpro:IPR038716|ensemblmetazoa:Y37E3.7.2(transcript)|ensemblmetazoa:Y37E3.7.3(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|ensemblmetazoa:WBGene00004409(gene)|ensemblmetazoa:Y37E3.7.1(transcript)|reactome:R-CEL-975956 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:trt7AQUJlZ8KHRDNlR9RTZ94nFc6239 rogid:WDBWJpk/M8F2b6aUJez0jkBGrPU6239 intact-crc:4B7C04B96A96A2EC|rigid:LCHhkx4iAjUINe4GXDm4q/Tw2Ig false - sufficient binding region:5-63("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91283 uniprotkb:E2JKZ0 intact:EBI-313421|ensemblmetazoa:F27C1.7a.1|ensemblmetazoa:F27C1.7a.2|ensemblmetazoa:F27C1.7a.3|ensemblmetazoa:F27C1.7a.4|ensemblmetazoa:F27C1.7a.5 intact:EBI-6457030|ensemblmetazoa:ZK593.5b.1 psi-mi:p91283_caeel(display_long)|uniprotkb:atp-3(gene name)|psi-mi:atp-3(display_short)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)|uniprotkb:CELE_F27C1.7(orf name)|uniprotkb:F27C1.7(orf name) psi-mi:e2jkz0_caeel(display_long)|uniprotkb:ZK593.5(orf name)|uniprotkb:dnc-1(gene name)|psi-mi:dnc-1(display_short)|uniprotkb:CELE_ZK593.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457027|imex:IM-11985-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021420.1|wormbase:F27C1.7a|ensemblmetazoa:F27C1.7a.1(transcript)|ensemblmetazoa:F27C1.7a.2(transcript)|ensemblmetazoa:F27C1.7a.3(transcript)|ensemblmetazoa:F27C1.7a.4(transcript)|ensemblmetazoa:F27C1.7a.5(transcript)|ensemblmetazoa:WBGene00000230(gene)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR026015|dip:DIP-26184N ensemblmetazoa:WBGene00001017(gene)|ensemblmetazoa:ZK593.5b.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005869"(dynactin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035047"(centrosomal and pronuclear rotation)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0035046"(pronuclear migration)|reactome:R-CEL-3371497|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|refseq:NP_001255521.1|wormbase:ZK593.5b|interpro:IPR036859|reactome:R-CEL-6807878|reactome:R-CEL-6811436 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:1NTGNlc9wMqgCOORpCDkRfohA3Y6239 rogid:rgH3mdKlbsoIrE4c92pnEVoEjQQ6239 intact-crc:F1609A422B0D377A|rigid:3iCFgjXSWRadH7ypCOLmdjVsM8w false - sufficient binding region:562-696("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:E2JKZ0 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-6457030|ensemblmetazoa:ZK593.5b.1 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:e2jkz0_caeel(display_long)|uniprotkb:ZK593.5(orf name)|uniprotkb:dnc-1(gene name)|psi-mi:dnc-1(display_short)|uniprotkb:CELE_ZK593.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457043|imex:IM-11985-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N ensemblmetazoa:WBGene00001017(gene)|ensemblmetazoa:ZK593.5b.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005869"(dynactin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035047"(centrosomal and pronuclear rotation)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0035046"(pronuclear migration)|reactome:R-CEL-3371497|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|refseq:NP_001255521.1|wormbase:ZK593.5b|interpro:IPR036859|reactome:R-CEL-6807878|reactome:R-CEL-6811436 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:rgH3mdKlbsoIrE4c92pnEVoEjQQ6239 intact-crc:E0BB10A1FBC4F2FF|rigid:QUUCrsMiGB5/1XmWNXK5yHseYW0 false - sufficient binding region:562-696("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:Q9XWK3 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457093|imex:IM-11985-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 intact-crc:B789BEF2168CA8E1|rigid:rhlygZE16Dr5+pO3PYTyISWwQU0 false - sufficient binding region:5-538("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q18529 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-314884|ensemblmetazoa:C39D10.7.2|ensemblmetazoa:C39D10.7.1 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q18529_caeel(display_long)|uniprotkb:C39D10.7(orf name)|uniprotkb:CELE_C39D10.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457063|imex:IM-11985-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) refseq:NP_509334.3|wormbase:C39D10.7|ensemblmetazoa:C39D10.7.2(transcript)|ensemblmetazoa:WBGene00016534(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0008061"(chitin binding)|interpro:IPR002557(Chitin binding protein, peritrophin-A)|interpro:IPR036508|ensemblmetazoa:C39D10.7.1(transcript)|dip:DIP-27006N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:gnU6jSkV05zYFXSGRFYUIcPLW5Q6239 intact-crc:818653DE33508319|rigid:gr9s1vT0ehLCswq0dAyrQshLbxM false - sufficient binding region:557-1171("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19207 uniprotkb:Q22799 intact:EBI-323336|ensemblmetazoa:F08F8.2.1 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:q19207_caeel(display_long)|uniprotkb:hmgr-1(gene name)|psi-mi:hmgr-1(display_short)|uniprotkb:F08F8.2(orf name)|uniprotkb:CELE_F08F8.2(orf name) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457073|imex:IM-11985-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498626.2|wormbase:F08F8.2|ensemblmetazoa:F08F8.2.1(transcript)|ensemblmetazoa:WBGene00017268(gene)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|dip:DIP-25409N|reactome:R-CEL-191273 refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:n+mz8S2n9i40K01p7ZmGHnh/Bu86239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:8464CC8BF7C70AE0|rigid:8aEsrWS8A/Cc8w1cXFe68wJPHHo false sufficient binding region:5-550("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17915 uniprotkb:Q86G90 intact:EBI-324099|ensemblmetazoa:K01G5.4.1 intact:EBI-313076|ensemblmetazoa:F59A2.1b.1|ensemblmetazoa:F59A2.1b.2|ensemblmetazoa:F59A2.1b.3 psi-mi:ran_caeel(display_long)|uniprotkb:ran-1(gene name)|psi-mi:ran-1(display_short)|uniprotkb:K01G5.4(orf name)|uniprotkb:Ras-related nuclear protein 1(gene name synonym) psi-mi:q86g90_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:F59A2.1(orf name)|uniprotkb:CELE_F59A2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457083|imex:IM-11985-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499369.1|wormbase:K01G5.4|ensemblmetazoa:K01G5.4.1(transcript)|ensemblmetazoa:WBGene00004302(gene)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CEL-1655829|dip:DIP-25217N|reactome:R-CEL-9615933 refseq:NP_871701.1|wormbase:F59A2.1b|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|ensemblmetazoa:F59A2.1b.1(transcript)|ensemblmetazoa:F59A2.1b.2(transcript)|ensemblmetazoa:F59A2.1b.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:yo75CoWqaTF5xYXAujyoTXXvRw86239 rogid:Y88l3qNpgk4xZvcOCx6msJeOHbo6239 intact-crc:F8C2438530A47F53|rigid:4dswB4HqGycRj9coHjDZiqTgSnY false - sufficient binding region:554-884("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18255 uniprotkb:Q19969 intact:EBI-314520|ensemblmetazoa:C27D9.1.1 intact:EBI-317340|uniprotkb:O44925|ensemblmetazoa:F32E10.4.1 psi-mi:q18255_caeel(display_long)|uniprotkb:C27D9.1(orf name)|uniprotkb:CELE_C27D9.1(orf name) psi-mi:ima3_caeel(display_long)|uniprotkb:ima-3(gene name)|psi-mi:ima-3(display_short)|uniprotkb:F32E10.4(orf name)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457123|imex:IM-11985-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009497(Protein of unknown function DUF1114)|wormbase:C27D9.1|refseq:NP_494851.2|ensemblmetazoa:C27D9.1.1(transcript)|ensemblmetazoa:WBGene00016163(gene)|go:"GO:0006486"(protein glycosylation)|go:"GO:0016020"(membrane)|go:"GO:0036065"(fucosylation)|go:"GO:0046920"("alpha-(1->3)-fucosyltransferase activity")|interpro:IPR001503(Glycosyl transferase, family 10)|reactome:R-CEL-9037629|reactome:R-CEL-975578 refseq:NP_501227.1|wormbase:F32E10.4|ensemblmetazoa:F32E10.4.1(transcript)|ensemblmetazoa:WBGene00002074(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007127"(meiosis I)|go:"GO:0007276"(gamete generation)|go:"GO:0007292"(female gamete generation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|dip:DIP-26417N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:2CAJcTLTMmwKH9AtJ6AH8xQxGK06239 rogid:WT7vezZFUUJSBWKoQXOmUoUD+xc6239 intact-crc:4F43F8EDA21F3E69|rigid:94rqleo/i5Rabb5wIB27/h3gnzc false - sufficient binding region:5-514("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16658 uniprotkb:Q22095 intact:EBI-2002051|ensemblmetazoa:C03H5.2.1 intact:EBI-2002048|ensemblmetazoa:T02C5.1a.1 psi-mi:o16658_caeel(display_long)|uniprotkb:C03H5.2(orf name)|uniprotkb:nstp-4(gene name)|psi-mi:nstp-4(display_short)|uniprotkb:CELE_C03H5.2(orf name) psi-mi:q22095_caeel(display_long)|uniprotkb:T02C5.1(orf name)|uniprotkb:CELE_T02C5.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457103|imex:IM-11985-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493723.3|wormbase:C03H5.2|interpro:IPR007271(Nucleotide-sugar transporter)|reactome:R-CEL-727802|ensemblmetazoa:C03H5.2.1(transcript)|ensemblmetazoa:WBGene00015404(gene)|go:"GO:0005459"(UDP-galactose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0030173"(integral component of Golgi membrane) refseq:NP_001024869.1|wormbase:T02C5.1a|dip:DIP-27184N|ensemblmetazoa:T02C5.1a.1(transcript)|ensemblmetazoa:WBGene00020158(gene)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Wvd85LmGaCHUGMUa+I1e01qJtpE6239 rogid:/+6KBtDRbAsCZ/jJaHA9GKzTuak6239 intact-crc:2F7780FD8C8FECAC|rigid:8UpidHCluDmpiNsZ+fHEf23iKqc false - sufficient binding region:55-375("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01488 uniprotkb:Q95QJ7 intact:EBI-320537|ensemblmetazoa:C13F10.2.1 intact:EBI-316069|uniprotkb:P34408|ensemblmetazoa:F22B7.13.1 psi-mi:o01488_caeel(display_long)|uniprotkb:kxd-1(gene name)|psi-mi:kxd-1(display_short)|uniprotkb:C13F10.2(orf name)|uniprotkb:CELE_C13F10.2(orf name) psi-mi:gpr1_caeel(display_long)|uniprotkb:F22B7.13(orf name)|uniprotkb:gpr-1(gene name)|psi-mi:gpr-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457113|imex:IM-11985-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504831.1|wormbase:C13F10.2|ensemblmetazoa:C13F10.2.1(transcript)|ensemblmetazoa:WBGene00015742(gene)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|dip:DIP-27148N refseq:NP_498900.1|wormbase:F22B7.13|ensemblmetazoa:F22B7.13.1(transcript)|ensemblmetazoa:WBGene00001688(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005818"(aster)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|dip:DIP-26900N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZX/rck9tSHblPGJKegKAjZiqxeA6239 rogid:O0UXQO2lBqcHpE5oqnCZ7mojj5g6239 intact-crc:516000BE8D9E95A0|rigid:loR0NLv11ROC9HDDFt9vwyYH67I false - sufficient binding region:5-525("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91349 uniprotkb:P91349 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457171|imex:IM-11985-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 intact-crc:7B165E7C91A9DBC8|rigid:txjo5TNwpZOK7I3+f9Wxn8QaaYc false - sufficient binding region:545-1198("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6457133 uniprotkb:Q19969 intact:EBI-6306363 intact:EBI-317340|uniprotkb:O44925|ensemblmetazoa:F32E10.4.1 psi-mi:ebi6306363(display_short)|psi-mi:EBI-6457133(display_long)|intact:F39H11.2x(author assigned name) psi-mi:ima3_caeel(display_long)|uniprotkb:ima-3(gene name)|psi-mi:ima-3(display_short)|uniprotkb:F32E10.4(orf name)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457137|imex:IM-11985-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_501227.1|wormbase:F32E10.4|ensemblmetazoa:F32E10.4.1(transcript)|ensemblmetazoa:WBGene00002074(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007127"(meiosis I)|go:"GO:0007276"(gamete generation)|go:"GO:0007292"(female gamete generation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|dip:DIP-26417N psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:WT7vezZFUUJSBWKoQXOmUoUD+xc6239 intact-crc:3FEA8333FABDDA58 false - sufficient binding region:5-514("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDE7 uniprotkb:G5EDL3 intact:EBI-324390|ensemblmetazoa:Y39G10AR.12a.1 intact:EBI-324340|ensemblmetazoa:K07C11.2.1|ensemblmetazoa:K07C11.2.2 psi-mi:g5ede7_caeel(display_long)|uniprotkb:tpxl-1(gene name)|psi-mi:tpxl-1(display_short)|uniprotkb:Y39G10AR.12(orf name)|uniprotkb:1C866(orf name)|uniprotkb:CELE_Y39G10AR.12(orf name) psi-mi:g5edl3_caeel(display_long)|uniprotkb:AIR-1(gene name synonym)|uniprotkb:air-1(gene name)|psi-mi:air-1(display_short)|uniprotkb:K07C11.2(orf name)|uniprotkb:CELE_K07C11.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457147|imex:IM-11985-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740805.1|uniprotkb:Q95XR5(uniprot-removed-ac)|wormbase:Y39G10AR.12a|ensemblmetazoa:WBGene00021470(gene)|go:"GO:0000235"(astral microtubule)|ensemblmetazoa:Y39G10AR.12a.1(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly) uniprotkb:Q21271(uniprot-removed-ac)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_505119.1|wormbase:K07C11.2|interpro:IPR030616|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904781"(positive regulation of protein localization to centrosome)|ensemblmetazoa:K07C11.2.1(transcript)|ensemblmetazoa:K07C11.2.2(transcript)|ensemblmetazoa:WBGene00000098(gene)|go:"GO:0000235"(astral microtubule) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:L8qyImbTKWJWTK7yRTb2pY3sJ1s6239 rogid:WWa/rjtXe6RruL7Ui72IJ5OJXxw6239 intact-crc:265BDDD4339D0DBA|rigid:bK0kpZh12QZOCeRU2FFWfMEJbT0 false sufficient binding region:5-507("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21774-1 uniprotkb:Q21774 intact:EBI-6457160|ensemblmetazoa:R06C7.5a.1|ensemblmetazoa:R06C7.5a.2 intact:EBI-2004707|uniprotkb:Q8I4G8|ensemblmetazoa:R06C7.5a.1|ensemblmetazoa:R06C7.5a.2 psi-mi:q21774-1(display_long)|uniprotkb:adsl-1(gene name)|psi-mi:adsl-1(display_short)|uniprotkb:Adenylosuccinase(gene name synonym)|uniprotkb:R06C7.5(orf name) psi-mi:pur8_caeel(display_long)|uniprotkb:adsl-1(gene name)|psi-mi:adsl-1(display_short)|uniprotkb:Adenylosuccinase(gene name synonym)|uniprotkb:R06C7.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457157|imex:IM-11985-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004707(isoform-parent)|ensemblmetazoa:R06C7.5a.1(transcript)|ensemblmetazoa:R06C7.5a.2(transcript)|ensemblmetazoa:WBGene00011064(gene) refseq:NP_492049.1|refseq:NP_871850.1|wormbase:R06C7.5a|wormbase:R06C7.5b|interpro:IPR019468|interpro:IPR000362(Fumarate lyase)|interpro:IPR020557|interpro:IPR008948(L-Aspartase-like)|interpro:IPR022761|rcsb pdb:1YIS|reactome:R-CEL-73817|ensemblmetazoa:R06C7.5a.1(transcript)|ensemblmetazoa:R06C7.5a.2(transcript)|ensemblmetazoa:WBGene00011064(gene)|go:"GO:0004018"("N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0070626"("(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity") psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:nsxIVDy+CvOUNUEFIYHsvkrV+wA6239 rogid:nsxIVDy+CvOUNUEFIYHsvkrV+wA6239 intact-crc:B630A7E1E7B2E4C7|rigid:Ju81BzJfapQcmYgBJ/5kqjZsGYI false - sufficient binding region:5-478("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23529 uniprotkb:Q9U2Z1 intact:EBI-1570263|uniprotkb:Q2V4T6|uniprotkb:Q7JPD4|ensemblmetazoa:ZK546.1b.1 intact:EBI-2006699|ensemblmetazoa:Y113G7A.3.1 psi-mi:hook_caeel(display_long)|uniprotkb:zyg-12(gene name)|psi-mi:zyg-12(display_short)|uniprotkb:ber-1(gene name synonym)|uniprotkb:ZK546.1(orf name) psi-mi:q9u2z1_caeel(display_long)|uniprotkb:sec-23(gene name)|psi-mi:sec-23(display_short)|uniprotkb:CELE_Y113G7A.3(orf name)|uniprotkb:Y113G7A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457211|imex:IM-11985-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:ZK546.1a|wormbase:ZK546.1b|wormbase:ZK546.1c|wormbase:ZK546.1d|refseq:NP_001293518.1|refseq:NP_001293519.1|refseq:NP_001293520.1|refseq:NP_001293521.1|interpro:IPR043936|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|ensemblmetazoa:WBGene00006997(gene)|ensemblmetazoa:ZK546.1b.1(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043621"(protein self-association)|go:"GO:0051642"(centrosome localization)|go:"GO:0051647"(nucleus localization)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport) reactome:R-CEL-983170|reactome:R-CEL-5694530|reactome:R-CEL-204005|refseq:NP_507877.1|wormbase:Y113G7A.3|interpro:IPR007123(Gelsolin region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|ensemblmetazoa:WBGene00004754(gene)|ensemblmetazoa:Y113G7A.3.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:TwBw0eaA5zYjRQ2ZA6oH2bSbLvs6239 rogid:TNoDPnGPQZoy+YFLVjfOYicIfls6239 intact-crc:1D249E8E1C9A8853|rigid:2f1SJs6cjrxI02caFiRnE15CplE false sufficient binding region:537-777("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:O62333 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457181|imex:IM-11985-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 intact-crc:FF95C20CB7047072|rigid:DDjGXte53DvuNi2qM6uxB0uQQIE false - sufficient binding region:5-419("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76371 uniprotkb:O17071 intact:EBI-317201|ensemblmetazoa:F56H1.4.1 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 psi-mi:prs6a_caeel(display_long)|uniprotkb:rpt-5(gene name)|psi-mi:rpt-5(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 5(gene name synonym)|uniprotkb:F56H1.4(orf name) psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457191|imex:IM-11985-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_491672.1|wormbase:F56H1.4|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F56H1.4.1(transcript)|ensemblmetazoa:WBGene00004505(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-CEL-5632684|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|interpro:IPR035254 refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:JW4UPtYlusTCwjDWZOAyH30g+Sw6239 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 intact-crc:B14E3BF5FCDDB8D4|rigid:qPrgZCPwA9r+67qFvKwR+XdC2pQ false - sufficient binding region:5-406("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23529 uniprotkb:P91409 intact:EBI-1570263|uniprotkb:Q2V4T6|uniprotkb:Q7JPD4|ensemblmetazoa:ZK546.1b.1 intact:EBI-326499|ensemblmetazoa:T01B11.3.1 psi-mi:hook_caeel(display_long)|uniprotkb:zyg-12(gene name)|psi-mi:zyg-12(display_short)|uniprotkb:ber-1(gene name synonym)|uniprotkb:ZK546.1(orf name) psi-mi:stx4_caeel(display_long)|uniprotkb:syx-4(gene name)|psi-mi:syx-4(display_short)|uniprotkb:syn-4(gene name synonym)|uniprotkb:T01B11.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457201|imex:IM-11985-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:ZK546.1a|wormbase:ZK546.1b|wormbase:ZK546.1c|wormbase:ZK546.1d|refseq:NP_001293518.1|refseq:NP_001293519.1|refseq:NP_001293520.1|refseq:NP_001293521.1|interpro:IPR043936|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|ensemblmetazoa:WBGene00006997(gene)|ensemblmetazoa:ZK546.1b.1(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043621"(protein self-association)|go:"GO:0051642"(centrosome localization)|go:"GO:0051647"(nucleus localization)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport) refseq:NP_501439.2|wormbase:T01B11.3|ensemblmetazoa:T01B11.3.1(transcript)|ensemblmetazoa:WBGene00006374(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|dip:DIP-26921N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:TwBw0eaA5zYjRQ2ZA6oH2bSbLvs6239 rogid:z2eki+gXRtD55A+1ho+rZvSSb9k6239 intact-crc:AB85B09EA90649DA|rigid:EeYNTUfNI4glvsMYGo8Vp87WId4 false sufficient binding region:537-777("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10986 uniprotkb:O45815 intact:EBI-321916|uniprotkb:Q7YSY2|ensemblmetazoa:M03F4.2a.1 intact:EBI-314481|ensemblmetazoa:T25C8.2.1|ensemblmetazoa:T25C8.2.2|ensemblmetazoa:T25C8.2.3 psi-mi:act4_caeel(display_long)|uniprotkb:act-4(gene name)|psi-mi:act-4(display_short)|uniprotkb:M03F4.2(orf name) psi-mi:o45815_caeel(display_long)|uniprotkb:act-5(gene name)|psi-mi:act-5(display_short)|uniprotkb:CELE_T25C8.2(orf name)|uniprotkb:T25C8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457251|imex:IM-11985-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508841.1|wormbase:M03F4.2a|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|ensemblmetazoa:M03F4.2a.1(transcript)|ensemblmetazoa:WBGene00000066(gene)|go:"GO:0000281"(mitotic cytokinesis)|dip:DIP-27204N refseq:NP_499809.1|wormbase:T25C8.2|ensemblmetazoa:T25C8.2.1(transcript)|ensemblmetazoa:T25C8.2.2(transcript)|ensemblmetazoa:T25C8.2.3(transcript)|ensemblmetazoa:WBGene00000067(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0035148"(tube formation)|go:"GO:0097516"(microvillar actin bundle)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:1990357"(terminal web)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-24432N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zehthX6Qo/gSO5k1j5Epcffr8Sc6239 rogid:sH4WCAz2hAFWd90um5at7FhG98Y6239 intact-crc:7429D8E78B9FEBF6|rigid:wMtz+L0ihqyHIvJs+XWmRbfhspk false - sufficient binding region:5-375("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:O61708 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-315255|ensemblmetazoa:R119.4.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:o61708_caeel(display_long)|uniprotkb:pqn-59(gene name)|psi-mi:pqn-59(display_short)|uniprotkb:CELE_R119.4(orf name)|uniprotkb:R119.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457221|imex:IM-11985-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_490727.1|wormbase:R119.4|ensemblmetazoa:R119.4.1(transcript)|ensemblmetazoa:WBGene00004143(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR009060(UBA-like)|dip:DIP-25020N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:K83JJthOIli1KrkmuKJbMtYpX7I6239 intact-crc:41D641CE46B426E4|rigid:PWvTJOh9ux1SIuC6SpbblVKQ1Qs false - sufficient binding region:537-712("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45970 uniprotkb:Q95QJ7 intact:EBI-320134|ensemblmetazoa:T09A5.10.1|ensemblmetazoa:T09A5.10.2 intact:EBI-316069|uniprotkb:P34408|ensemblmetazoa:F22B7.13.1 psi-mi:lin5_caeel(display_long)|uniprotkb:lin-5(gene name)|psi-mi:lin-5(display_short)|uniprotkb:T09A5.10(orf name)|uniprotkb:Abnormal cell lineage protein 5(gene name synonym) psi-mi:gpr1_caeel(display_long)|uniprotkb:F22B7.13(orf name)|uniprotkb:gpr-1(gene name)|psi-mi:gpr-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457231|imex:IM-11985-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495654.1|wormbase:T09A5.10|ensemblmetazoa:T09A5.10.1(transcript)|ensemblmetazoa:T09A5.10.2(transcript)|ensemblmetazoa:WBGene00002994(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0008406"(gonad development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0040011"(locomotion)|go:"GO:0051233"(spindle midzone)|go:"GO:0051296"(establishment of meiotic spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|dip:DIP-24397N refseq:NP_498900.1|wormbase:F22B7.13|ensemblmetazoa:F22B7.13.1(transcript)|ensemblmetazoa:WBGene00001688(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005818"(aster)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|dip:DIP-26900N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:P55+FcFiYu1Or6aQZkef89JaIE86239 rogid:O0UXQO2lBqcHpE5oqnCZ7mojj5g6239 intact-crc:05022323C97AC2DA|rigid:7ne7ooYz4/+dTfDseKma8UoMNxk false sufficient binding region:537-671("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10983 uniprotkb:P10983 intact:EBI-312653|uniprotkb:P10985 intact:EBI-312653|uniprotkb:P10985 psi-mi:act1_caeel(display_long)|uniprotkb:act-1(gene name)|psi-mi:act-1(display_short)|uniprotkb:T04C12.4(orf name)|uniprotkb:act-3(gene name)|psi-mi:act-3(display_short)|uniprotkb:T04C12.6(orf name) psi-mi:act1_caeel(display_long)|uniprotkb:act-1(gene name)|psi-mi:act-1(display_short)|uniprotkb:T04C12.4(orf name)|uniprotkb:act-3(gene name)|psi-mi:act-3(display_short)|uniprotkb:T04C12.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457241|imex:IM-11985-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005524"(ATP binding)|go:"GO:0007517"(muscle organ development)|refseq:NP_505817.1|refseq:NP_505819.1|wormbase:T04C12.4|wormbase:T04C12.6|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|rcsb pdb:1D4X|go:"GO:0009790"(embryo development)|go:"GO:0030036"(actin cytoskeleton organization) go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005524"(ATP binding)|go:"GO:0007517"(muscle organ development)|refseq:NP_505817.1|refseq:NP_505819.1|wormbase:T04C12.4|wormbase:T04C12.6|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|rcsb pdb:1D4X|go:"GO:0009790"(embryo development)|go:"GO:0030036"(actin cytoskeleton organization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:FfocOk3zTuKPi2M4G/gWUnYn5Dc6239 rogid:FfocOk3zTuKPi2M4G/gWUnYn5Dc6239 intact-crc:FE5C50D3EC550679|rigid:DVQ8HdBM2+WrKFqElC5WlWuGPj0 false sufficient binding region:5-376("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94392 uniprotkb:Q27488 intact:EBI-316816|ensemblmetazoa:H15N14.2a.1 intact:EBI-318271|ensemblmetazoa:D1054.2.1|ensemblmetazoa:D1054.2.2 psi-mi:nsf_caeel(display_long)|uniprotkb:H15N14.2(orf name)|uniprotkb:nsf-1(gene name)|psi-mi:nsf-1(display_short)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym) psi-mi:psa2_caeel(display_long)|uniprotkb:pas-2(gene name)|psi-mi:pas-2(display_short)|uniprotkb:D1054.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457291|imex:IM-11985-170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6807878|reactome:R-CEL-204005|refseq:NP_001076603.1|wormbase:H15N14.2a|reactome:R-CEL-6811438|reactome:R-CEL-6811440|ensemblmetazoa:H15N14.2a.1(transcript)|ensemblmetazoa:WBGene00003818(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005795"(Golgi stack)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|dip:DIP-24326N|reactome:R-CEL-6811434 refseq:NP_505750.1|wormbase:D1054.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034644|reactome:R-CEL-5687128|interpro:IPR029055|reactome:R-CEL-187577|ensemblmetazoa:D1054.2.1(transcript)|ensemblmetazoa:D1054.2.2(transcript)|ensemblmetazoa:WBGene00003923(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aRp2HvXAWW2KJuimcz+d4XfBEVI6239 rogid:oxMITWZNzWRcUpGSL6T7pKrm+Xs6239 intact-crc:1CA9129959117222|rigid:VxP26g7ZZpjsosu1HkgkiacTBNk false sufficient binding region:536-824("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10984 uniprotkb:O45815 intact:EBI-316166|uniprotkb:O45744|ensemblmetazoa:T04C12.5.1|ensemblmetazoa:T04C12.5.2|ensemblmetazoa:T04C12.5.3 intact:EBI-314481|ensemblmetazoa:T25C8.2.1|ensemblmetazoa:T25C8.2.2|ensemblmetazoa:T25C8.2.3 psi-mi:act2_caeel(display_long)|uniprotkb:act-2(gene name)|psi-mi:act-2(display_short)|uniprotkb:T04C12.5(orf name) psi-mi:o45815_caeel(display_long)|uniprotkb:act-5(gene name)|psi-mi:act-5(display_short)|uniprotkb:CELE_T25C8.2(orf name)|uniprotkb:T25C8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457261|imex:IM-11985-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505818.1|wormbase:T04C12.5|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|ensemblmetazoa:T04C12.5.1(transcript)|ensemblmetazoa:T04C12.5.2(transcript)|ensemblmetazoa:T04C12.5.3(transcript)|ensemblmetazoa:WBGene00000064(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040011"(locomotion)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-25116N refseq:NP_499809.1|wormbase:T25C8.2|ensemblmetazoa:T25C8.2.1(transcript)|ensemblmetazoa:T25C8.2.2(transcript)|ensemblmetazoa:T25C8.2.3(transcript)|ensemblmetazoa:WBGene00000067(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0035148"(tube formation)|go:"GO:0097516"(microvillar actin bundle)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:1990357"(terminal web)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-24432N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pqXk6IfTnhM0CgPVRlu+EK57pDs6239 rogid:sH4WCAz2hAFWd90um5at7FhG98Y6239 intact-crc:3CDBFDDB78501317|rigid:oipg53Ji2EHpfhqUxkZBNKqQXug false - sufficient binding region:5-375("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10983 uniprotkb:O45815 intact:EBI-312653|uniprotkb:P10985 intact:EBI-314481|ensemblmetazoa:T25C8.2.1|ensemblmetazoa:T25C8.2.2|ensemblmetazoa:T25C8.2.3 psi-mi:act1_caeel(display_long)|uniprotkb:act-1(gene name)|psi-mi:act-1(display_short)|uniprotkb:T04C12.4(orf name)|uniprotkb:act-3(gene name)|psi-mi:act-3(display_short)|uniprotkb:T04C12.6(orf name) psi-mi:o45815_caeel(display_long)|uniprotkb:act-5(gene name)|psi-mi:act-5(display_short)|uniprotkb:CELE_T25C8.2(orf name)|uniprotkb:T25C8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457271|imex:IM-11985-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005524"(ATP binding)|go:"GO:0007517"(muscle organ development)|refseq:NP_505817.1|refseq:NP_505819.1|wormbase:T04C12.4|wormbase:T04C12.6|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|rcsb pdb:1D4X|go:"GO:0009790"(embryo development)|go:"GO:0030036"(actin cytoskeleton organization) refseq:NP_499809.1|wormbase:T25C8.2|ensemblmetazoa:T25C8.2.1(transcript)|ensemblmetazoa:T25C8.2.2(transcript)|ensemblmetazoa:T25C8.2.3(transcript)|ensemblmetazoa:WBGene00000067(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0035148"(tube formation)|go:"GO:0097516"(microvillar actin bundle)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:1990357"(terminal web)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-24432N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:FfocOk3zTuKPi2M4G/gWUnYn5Dc6239 rogid:sH4WCAz2hAFWd90um5at7FhG98Y6239 intact-crc:19B4800015E7E644|rigid:bPfXrG2UYJ1AUw6AIpz4Y37jwxE false - sufficient binding region:5-375("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WT44 uniprotkb:P34286 intact:EBI-2002025|uniprotkb:G5EDU8|ensemblmetazoa:ZK328.1b.1 intact:EBI-313778|uniprotkb:Q9BMU3|ensemblmetazoa:C02F5.9.1 psi-mi:ubph_caeel(display_long)|uniprotkb:CeUBP130(gene name synonym)|uniprotkb:Cytokinesis defective protein 3(gene name synonym)|uniprotkb:uch-1(gene name synonym)|uniprotkb:ZK328.1(orf name)|uniprotkb:cyk-3(gene name)|psi-mi:cyk-3(display_short) psi-mi:psb1_caeel(display_long)|uniprotkb:pbs-6(gene name)|psi-mi:pbs-6(display_short)|uniprotkb:C02F5.9(orf name)|uniprotkb:Proteasome subunit beta 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457281|imex:IM-11985-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022992.1|wormbase:ZK328.1b|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|refseq:NP_498311.2|interpro:IPR035927|interpro:IPR038765|wormbase:ZK328.1a|reactome:R-CEL-5689880|ensemblmetazoa:WBGene00000874(gene)|ensemblmetazoa:ZK328.1b.1(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904785"(regulation of asymmetric protein localization involved in cell fate determination)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization) reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_498806.1|wormbase:C02F5.9|reactome:R-CEL-5632684|ensemblmetazoa:C02F5.9.1(transcript)|ensemblmetazoa:WBGene00003952(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-24619N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LbOi5WL6TFO24ZC3+KhxtzJ/8ZY6239 rogid:g54+kg5aHsaQMTBH6xZ9h0/20XQ6239 intact-crc:79BAD6E19F52F5F3|rigid:8pDK/0r2sMbMTWdK9T5K/St6xAo false sufficient binding region:537-1004("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19371 uniprotkb:Q9U2Z1 intact:EBI-2005696|ensemblmetazoa:F12F6.6.1 intact:EBI-2006699|ensemblmetazoa:Y113G7A.3.1 psi-mi:q19371_caeel(display_long)|uniprotkb:sec-24.1(gene name)|psi-mi:sec-24.1(display_short)|uniprotkb:CELE_F12F6.6(orf name)|uniprotkb:F12F6.6(orf name) psi-mi:q9u2z1_caeel(display_long)|uniprotkb:sec-23(gene name)|psi-mi:sec-23(display_short)|uniprotkb:CELE_Y113G7A.3(orf name)|uniprotkb:Y113G7A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457321|imex:IM-11985-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502178.1|wormbase:F12F6.6|interpro:IPR007123(Gelsolin region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|reactome:R-CEL-204005|reactome:R-CEL-5694530|reactome:R-CEL-983170|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|ensemblmetazoa:F12F6.6.1(transcript)|ensemblmetazoa:WBGene00004755(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) reactome:R-CEL-983170|reactome:R-CEL-5694530|reactome:R-CEL-204005|refseq:NP_507877.1|wormbase:Y113G7A.3|interpro:IPR007123(Gelsolin region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|ensemblmetazoa:WBGene00004754(gene)|ensemblmetazoa:Y113G7A.3.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:dg1hd9LmcymwnqpcxF0TbE37fZA6239 rogid:TNoDPnGPQZoy+YFLVjfOYicIfls6239 intact-crc:2BAD78C0158E2246|rigid:4C0aMK60sDe9d7oM9sgVQ0wuw6w false sufficient binding region:531-735("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94392 uniprotkb:Q94392 intact:EBI-316816|ensemblmetazoa:H15N14.2a.1 intact:EBI-316816|ensemblmetazoa:H15N14.2a.1 psi-mi:nsf_caeel(display_long)|uniprotkb:H15N14.2(orf name)|uniprotkb:nsf-1(gene name)|psi-mi:nsf-1(display_short)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym) psi-mi:nsf_caeel(display_long)|uniprotkb:H15N14.2(orf name)|uniprotkb:nsf-1(gene name)|psi-mi:nsf-1(display_short)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457301|imex:IM-11985-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6807878|reactome:R-CEL-204005|refseq:NP_001076603.1|wormbase:H15N14.2a|reactome:R-CEL-6811438|reactome:R-CEL-6811440|ensemblmetazoa:H15N14.2a.1(transcript)|ensemblmetazoa:WBGene00003818(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005795"(Golgi stack)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|dip:DIP-24326N|reactome:R-CEL-6811434 reactome:R-CEL-6807878|reactome:R-CEL-204005|refseq:NP_001076603.1|wormbase:H15N14.2a|reactome:R-CEL-6811438|reactome:R-CEL-6811440|ensemblmetazoa:H15N14.2a.1(transcript)|ensemblmetazoa:WBGene00003818(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005795"(Golgi stack)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|dip:DIP-24326N|reactome:R-CEL-6811434 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aRp2HvXAWW2KJuimcz+d4XfBEVI6239 rogid:aRp2HvXAWW2KJuimcz+d4XfBEVI6239 intact-crc:F4385DA72608C434|rigid:dnHe45BBER+7P1c1SkIDD64VksA false sufficient binding region:536-824("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22253 uniprotkb:P53016 intact:EBI-326317|ensemblmetazoa:T06D8.8.1|ensemblmetazoa:T06D8.8.2 intact:EBI-318155|ensemblmetazoa:F31E3.3.1 psi-mi:q22253_caeel(display_long)|uniprotkb:rpn-9(gene name)|psi-mi:rpn-9(display_short)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:CELE_T06D8.8(orf name)|uniprotkb:T06D8.8(orf name) psi-mi:rfc4_caeel(display_long)|uniprotkb:F31E3.3(orf name)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:rfc-4(gene name)|psi-mi:rfc-4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457311|imex:IM-11985-172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_496405.1|wormbase:T06D8.8|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-1234176|reactome:R-CEL-1236978|ensemblmetazoa:T06D8.8.1(transcript)|ensemblmetazoa:T06D8.8.2(transcript)|ensemblmetazoa:WBGene00004465(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043248"(proteasome assembly)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR035298|interpro:IPR036390|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-8932339 refseq:NP_498521.1|wormbase:F31E3.3|ensemblmetazoa:F31E3.3.1(transcript)|ensemblmetazoa:WBGene00004340(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|dip:DIP-24293N|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-110320|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-69091 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:AS9yH/PgziWyyFfsUDf2NE1M4iw6239 rogid:17GeJI7eKmB2+zqvOLntNT/n4eo6239 intact-crc:50C7426B35824A0E|rigid:2F6suogm3JwhPHtdhuQoez5F3mk false - sufficient binding region:5-334("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 uniprotkb:P91082 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 intact:EBI-2002373|uniprotkb:A0A0K3AWT5|ensemblmetazoa:C23H3.1a.1 psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:egl26_caeel(display_long)|uniprotkb:egl-26(gene name)|psi-mi:egl-26(display_short)|uniprotkb:Putative acyltransferase egl-26(gene name synonym)|uniprotkb:cog-4(gene name synonym)|uniprotkb:egl-48(gene name synonym)|uniprotkb:C23H3.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457361|imex:IM-11985-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) refseq:NP_493652.1|wormbase:C23H3.1a|interpro:IPR007053(NC)|wormbase:C23H3.1b|ensemblmetazoa:C23H3.1a.1(transcript)|ensemblmetazoa:WBGene00001193(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002119"(nematode larval development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:TEM2NJQmEPUiCvqWHItpREWKEII6239 intact-crc:0989CCEB1DC41320|rigid:9e02t1JAg75kCBz6CKtHmie9n9Y false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:Q21021 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457331|imex:IM-11985-174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 intact-crc:FD8BD831A51AD9A0|rigid:X0ilTVEUuelQ6YmmvfDbvNj+qm4 false sufficient binding region:530-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18688 uniprotkb:Q18688 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457341|imex:IM-11985-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 intact-crc:4E9A6A1494D0FF92|rigid:q6hElnoEycKZouK9tgxpKqfmeVk false sufficient binding region:528-702("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 uniprotkb:O61955-1 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 intact:EBI-6456691|ensemblmetazoa:B0348.6b.1|ensemblmetazoa:B0348.6b.2 psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:o61955-1(display_long)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:B0348.6(orf name)|uniprotkb:ife-3(gene name)|psi-mi:ife-3(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457351|imex:IM-11985-176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) intact:EBI-330119(isoform-parent)|ensemblmetazoa:B0348.6b.1(transcript)|ensemblmetazoa:B0348.6b.2(transcript)|ensemblmetazoa:WBGene00002061(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:444BHWm5Eiqg+MUqKRgLhbVaxUo6239 intact-crc:7F65CF2C00BBCC88|rigid:9BvbpakeT8+caMoOC8OFXMwfiqo false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFA9 uniprotkb:Q1ZXS5-2 intact:EBI-6457394|ensemblmetazoa:C52D10.7.1 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:g5efa9_caeel(display_long)|uniprotkb:C52D10.7(orf name)|uniprotkb:skr-9(gene name)|psi-mi:skr-9(display_short)|uniprotkb:CELE_C52D10.7(orf name) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457391|imex:IM-11985-180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C52D10.7.1(transcript)|ensemblmetazoa:WBGene00004815(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_503043.1|wormbase:C52D10.7|interpro:IPR036296 intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:TCdjs4T6zXW+/6oX4z3lFH4hBKQ6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:AA86EB92563C78F4|rigid:1j2ZSnPSxZhEsX19oBPc9lTvRpA false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 uniprotkb:Q95YD5 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 intact:EBI-313806|ensemblmetazoa:C30F8.2.1|ensemblmetazoa:C30F8.2.2|ensemblmetazoa:C30F8.2.3 psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:q95yd5_caeel(display_long)|uniprotkb:vha-16(gene name)|psi-mi:vha-16(display_short)|uniprotkb:CELE_C30F8.2(orf name)|uniprotkb:C30F8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457371|imex:IM-11985-178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) refseq:NP_491515.2|wormbase:C30F8.2|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|reactome:R-CEL-77387|reactome:R-CEL-1222556|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|ensemblmetazoa:C30F8.2.1(transcript)|ensemblmetazoa:C30F8.2.2(transcript)|ensemblmetazoa:C30F8.2.3(transcript)|ensemblmetazoa:WBGene00016258(gene)|go:"GO:0005769"(early endosome)|go:"GO:0007034"(vacuolar transport)|interpro:IPR044911|interpro:IPR035067|interpro:IPR036079|reactome:R-CEL-917977|reactome:R-CEL-983712|reactome:R-CEL-9639288 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:1GQOWcfyhwox5dRmSUc3JdSShKM6239 intact-crc:1AAEFD87FD820AC3|rigid:rtLd2LEGFyKZdCFettgVs0Utb8M false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46561 uniprotkb:Q1ZXS5-2 intact:EBI-316294|ensemblmetazoa:C34E10.6.1|ensemblmetazoa:C34E10.6.2|ensemblmetazoa:C34E10.6.3 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:atpb_caeel(display_long)|uniprotkb:atp-2(gene name)|psi-mi:atp-2(display_short)|uniprotkb:C34E10.6(orf name) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457381|imex:IM-11985-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-1268020|refseq:NP_498111.2|wormbase:C34E10.6|ensemblmetazoa:C34E10.6.1(transcript)|ensemblmetazoa:C34E10.6.2(transcript)|ensemblmetazoa:C34E10.6.3(transcript)|ensemblmetazoa:WBGene00000229(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005929"(cilium)|go:"GO:0007617"(mating behavior)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030421"(defecation)|go:"GO:0040024"(dauer larval development)|go:"GO:0040039"(inductive cell migration)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043050"(pharyngeal pumping)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0097730"(non-motile cilium)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|dip:DIP-24363N|reactome:R-CEL-163210|reactome:R-CEL-8949613 intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:7NyQvjFV+TNx6et/+gylNZki55U6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:C012827FB99ACDB3|rigid:tYW9qPRlSQXqhDd7fCfaVK9SnYc false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 intact:EBI-2007111 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 - psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:q19924_caeel(display_short)|psi-mi:EBI-2007111(display_long)|uniprotkb:F31A9.2(orf name)|uniprotkb:CELE_F31A9.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457436|imex:IM-11985-184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) uniprotkb:Q19924(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:yzla4mtsMhA90GSQWCQ2tRvsJuE6239 intact-crc:29BFCFFDFEE560DF|rigid:I8d8WbH55sVSKEYRAg/vd8+DopU false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09510 uniprotkb:Q1ZXS5-2 intact:EBI-316980|ensemblmetazoa:C56G7.1.1 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:mlrh_caeel(display_long)|uniprotkb:mlc-4(gene name)|psi-mi:mlc-4(display_short)|uniprotkb:Non-muscle myosin regulatory light chain(gene name synonym)|uniprotkb:C56G7.1(orf name) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457406|imex:IM-11985-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497700.1|wormbase:C56G7.1|reactome:R-CEL-5627123|reactome:R-CEL-3928664|reactome:R-CEL-445355|ensemblmetazoa:C56G7.1.1(transcript)|ensemblmetazoa:WBGene00003372(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0002119"(nematode larval development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031941"(filamentous actin)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|go:"GO:0007110"(meiosis I cytokinesis)|dip:DIP-25307N intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:oj5E0iY1pIPNm+i1bRJbphNTWFc6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:00BD14929515BC51|rigid:jTynYlk0EkxFCMFiQxJpukUG1Fo false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54412 uniprotkb:Q1ZXS5-2 intact:EBI-313179|uniprotkb:Q2PJ76|uniprotkb:Q8I4K9|ensemblmetazoa:F17C11.9a.1|ensemblmetazoa:F17C11.9a.2 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:ef1g_caeel(display_long)|uniprotkb:eef-1G(gene name)|psi-mi:eef-1G(display_short)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:F17C11.9(orf name) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457416|imex:IM-11985-182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F17C11.9b|wormbase:F17C11.9c|refseq:NP_505800.1|wormbase:F17C11.9a|ensemblmetazoa:F17C11.9a.1(transcript)|ensemblmetazoa:F17C11.9a.2(transcript)|ensemblmetazoa:WBGene00008920(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006414"(translational elongation)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|refseq:NP_001041100.1|refseq:NP_872125.1|interpro:IPR036282|interpro:IPR036433|dip:DIP-24841N intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:2BIJ7hlPD7CoxwYAi/JViA0QK4M6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:D73491898F299191|rigid:docMu3F5XNo/2hkbwP2WJW/Lswk false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 uniprotkb:G5EDR3 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 intact:EBI-2003301|ensemblmetazoa:F26E4.1.1 psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:2ab1_caeel(display_long)|uniprotkb:sur-6(gene name)|psi-mi:sur-6(display_short)|uniprotkb:Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit sur-6(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B sur-6(gene name synonym)|uniprotkb:F26E4.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457426|imex:IM-11985-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) uniprotkb:P90851(uniprot-removed-ac)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_492591.1|wormbase:F26E4.1|reactome:R-CEL-69231|reactome:R-CEL-2995383|reactome:R-CEL-69273|interpro:IPR036322|reactome:R-CEL-975957|ensemblmetazoa:F26E4.1.1(transcript)|ensemblmetazoa:WBGene00006352(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0002119"(nematode larval development)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0070262"(peptidyl-serine dephosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:vgojL7SRpj6x34AcKSzU5qCBHIs6239 intact-crc:B57560F44489FFD9|rigid:Z7VuKa31Lin7DWDlPUD6RFhb6es false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 uniprotkb:G5ED39 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 intact:EBI-326265|ensemblmetazoa:Y47G6A.12.1|ensemblmetazoa:Y47G6A.12.2 psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:sep1_caeel(display_long)|uniprotkb:sep-1(gene name)|psi-mi:sep-1(display_short)|uniprotkb:Separase(gene name synonym)|uniprotkb:Y47G6A.12(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457466|imex:IM-11985-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) uniprotkb:Q9N3T9(uniprot-removed-ac)|wormbase:Y47G6A.12|reactome:R-CEL-2467813|interpro:IPR030397|ensemblmetazoa:WBGene00004775(gene)|ensemblmetazoa:Y47G6A.12.1(transcript)|ensemblmetazoa:Y47G6A.12.2(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005938"(cell cortex)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0016485"(protein processing)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0030703"(eggshell formation)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0061062"(regulation of nematode larval development)|go:"GO:0070090"(metaphase plate)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0048609"(multicellular organismal reproductive process)|interpro:IPR005314(Peptidase C50, separase)|refseq:NP_491160.1|rcsb pdb:5MZ6 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:qq5TbHApz1ewXGjRURnd2HAtNaI6239 intact-crc:B2B014921C140441|rigid:QCXl4z2snpFmxrmv7LiHMj1INdI false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EGK8 uniprotkb:Q1ZXS5-2 intact:EBI-319655|ensemblmetazoa:F38H4.9.1|ensemblmetazoa:F38H4.9.2|ensemblmetazoa:F38H4.9.3 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:pp2a_caeel(display_long)|uniprotkb:let-92(gene name)|psi-mi:let-92(display_short)|uniprotkb:F38H4.9(orf name) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457446|imex:IM-11985-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q27498(uniprot-removed-ac)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_502247.1|ensemblmetazoa:F38H4.9.1(transcript)|ensemblmetazoa:F38H4.9.2(transcript)|ensemblmetazoa:F38H4.9.3(transcript)|ensemblmetazoa:WBGene00002363(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0018985"(pronuclear envelope synthesis)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046872"(metal ion binding)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0106306"|go:"GO:0106307"|wormbase:F38H4.9|reactome:R-CEL-389513|reactome:R-CEL-6811558|interpro:IPR029052|reactome:R-CEL-5673000|reactome:R-CEL-5675221|reactome:R-CEL-69231|reactome:R-CEL-195253|reactome:R-CEL-198753|reactome:R-CEL-202670|reactome:R-CEL-2995383|reactome:R-CEL-69273|reactome:R-CEL-196299|reactome:R-CEL-975957 intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:d5e/T74YELePZOaa8rUlLe8oWw86239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:5CE9D91E746F9BA2|rigid:oJEmHkNf5Ck48TRyIDHOuy9FedY false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5U1 uniprotkb:Q1ZXS5-2 intact:EBI-2005375|ensemblmetazoa:T22F3.3a.1 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:q9n5u1_caeel(display_long)|uniprotkb:pygl-1(gene name)|psi-mi:pygl-1(display_short)|uniprotkb:CELE_T22F3.3(orf name)|uniprotkb:T22F3.3(orf name) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457456|imex:IM-11985-186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504007.1|wormbase:T22F3.3a|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|reactome:R-CEL-70221|interpro:IPR035090|ensemblmetazoa:T22F3.3a.1(transcript)|ensemblmetazoa:WBGene00020696(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:hxlfa3e+4GTuwc4kabxrVxbDecs6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:C74E76BF0D8321AE|rigid:hK0nTeUJV+5z1OZ/rNn+egH3/ls false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 uniprotkb:Q9N4I0 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 intact:EBI-2421498|ensemblmetazoa:Y71F9AL.16.1 psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:arp3_caeel(display_long)|uniprotkb:Actin-like protein 3(gene name synonym)|uniprotkb:Y71F9AL.16(orf name)|uniprotkb:arx-1(gene name)|psi-mi:arx-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457476|imex:IM-11985-188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) interpro:IPR015623(Actin-related protein 3)|refseq:NP_491066.1|wormbase:Y71F9AL.16|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|reactome:R-CEL-8856828|reactome:R-CEL-2029482|reactome:R-CEL-5663213|interpro:IPR043129|reactome:R-CEL-3928662|ensemblmetazoa:WBGene00000199(gene)|ensemblmetazoa:Y71F9AL.16.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0007369"(gastrulation)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0031252"(cell leading edge)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:irFvd00QXHsUpZgZ2DlicyVun306239 intact-crc:6DE6888F9526F399|rigid:pcrrdbENPKGa1HbiXSYN3MF0AgI false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4G9 uniprotkb:Q1ZXS5-2 intact:EBI-2411974|ensemblmetazoa:Y71F9B.4.1 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:ruxg_caeel(display_long)|uniprotkb:Y71F9B.4(orf name)|uniprotkb:snr-7(gene name)|psi-mi:snr-7(display_short)|uniprotkb:Sm protein G(gene name synonym) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457486|imex:IM-11985-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491032.1|wormbase:Y71F9B.4|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|reactome:R-CEL-72163|reactome:R-CEL-72165|interpro:IPR034098|reactome:R-CEL-111367|reactome:R-CEL-191859|reactome:R-CEL-73856|reactome:R-CEL-77588|interpro:IPR044641|ensemblmetazoa:WBGene00004920(gene)|ensemblmetazoa:Y71F9B.4.1(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043186"(P granule)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990904"(ribonucleoprotein complex) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:NBc301PkpVImlVz5VuQ9cLa2vQY6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:92832C5315EE2A99|rigid:HLcoL1oQGqEGQVWF4x31ZqSXyLg false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4A7-1 uniprotkb:Q1ZXS5-2 intact:EBI-6456140|ensemblmetazoa:Y77E11A.13a.1 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:q9n4a7-1(display_long)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:Nuclear pore complex protein 20(gene name synonym)|uniprotkb:npp-20(gene name)|psi-mi:npp-20(display_short)|uniprotkb:CeSec13R(gene name synonym)|uniprotkb:sec-13(gene name synonym)|uniprotkb:Y77E11A.13(orf name) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457496|imex:IM-11985-190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318290(isoform-parent)|ensemblmetazoa:WBGene00003806(gene)|ensemblmetazoa:Y77E11A.13a.1(transcript) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:ZKmmnaa7DFkQzBBKNad56Ic7GvI6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:B3FF36DA814E7825|rigid:55VZPlWsVoPBFoFTU/BIM6xaJds false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 uniprotkb:G5EF02 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 intact:EBI-2006627|ensemblmetazoa:ZC404.8.1|ensemblmetazoa:ZC404.8.2 psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:g5ef02_caeel(display_long)|uniprotkb:spn-4(gene name)|psi-mi:spn-4(display_short)|uniprotkb:pip-1(gene name synonym)|uniprotkb:CELE_ZC404.8(orf name)|uniprotkb:ZC404.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457506|imex:IM-11985-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) refseq:NP_504717.1|interpro:IPR000504(RNA recognition motif, RNP-1)|uniprotkb:Q23287(uniprot-removed-ac)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|wormbase:ZC404.8|interpro:IPR035979|ensemblmetazoa:WBGene00004984(gene)|ensemblmetazoa:ZC404.8.1(transcript)|ensemblmetazoa:ZC404.8.2(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0043186"(P granule) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:ZNS95NnjE22x50ovVVqCar1ExxE6239 intact-crc:1172EB2EF857F7B6|rigid:axQTYwfK8/cexFgqxeGBPmalgMw false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q1ZXS5-2 uniprotkb:Q23680 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 intact:EBI-329074|ensemblmetazoa:ZK970.4.1|ensemblmetazoa:ZK970.4.2 psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:vatf_caeel(display_long)|uniprotkb:ZK970.4(orf name)|uniprotkb:Vacuolar proton pump subunit F(gene name synonym)|uniprotkb:vha-9(gene name)|psi-mi:vha-9(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457541|imex:IM-11985-194 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) refseq:NP_496217.1|wormbase:ZK970.4|reactome:R-CEL-1222556|reactome:R-CEL-77387|dip:DIP-25749N|ensemblmetazoa:WBGene00006918(gene)|ensemblmetazoa:ZK970.4.1(transcript)|ensemblmetazoa:ZK970.4.2(transcript)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016020"(membrane)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0042625"(ATPase-coupled ion transmembrane transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR005772(ATPase, V1 complex, subunit F, eukaryotic)|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|interpro:IPR036906|reactome:R-CEL-9639288|reactome:R-CEL-917977|reactome:R-CEL-983712 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 rogid:PW1um9kr3M14YyjWUHwmpeITSKc6239 intact-crc:68AE7A670D9EDF47|rigid:A5aw2NkwHiV7vEt9fU4Ia/qW8zg false sufficient binding region:526-923("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23312 uniprotkb:Q1ZXS5-2 intact:EBI-312733|ensemblmetazoa:ZC434.2.1 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:rs7_caeel(display_long)|uniprotkb:ZC434.2(orf name)|uniprotkb:rps-7(gene name)|psi-mi:rps-7(display_short) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457516|imex:IM-11985-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492708.1|wormbase:ZC434.2|reactome:R-CEL-6791226|ensemblmetazoa:WBGene00004476(gene)|ensemblmetazoa:ZC434.2.1(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR000554(Ribosomal protein S7e)|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975957|reactome:R-CEL-975956|reactome:R-CEL-72649|dip:DIP-26439N intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:gnd5rFG34vp8piSiNoTt+PbQvyo6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:A32D31465FA1A96D|rigid:LhtVIL9vOGfNv5e6SQdjOH4N1ZE false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MPS6 uniprotkb:Q1ZXS5-2 intact:EBI-6457529|ensemblmetazoa:ZK742.1b.1|ensemblmetazoa:ZK742.1b.2|ensemblmetazoa:ZK742.1b.3 intact:EBI-16491075|ensemblmetazoa:T08G5.5a.1 psi-mi:q8mps6_caeel(display_long)|uniprotkb:ZK742.1(orf name)|uniprotkb:xpo-1(gene name)|psi-mi:xpo-1(display_short)|uniprotkb:CELE_ZK742.1(orf name) psi-mi:q1zxs5-2(display_long)|uniprotkb:vps-39(gene name)|psi-mi:vps-39(display_short)|uniprotkb:T08G5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457526|imex:IM-11985-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00002078(gene)|ensemblmetazoa:ZK742.1b.1(transcript)|ensemblmetazoa:ZK742.1b.2(transcript)|ensemblmetazoa:ZK742.1b.3(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_741568.1|wormbase:ZK742.1b intact:EBI-318975(isoform-parent)|ensemblmetazoa:T08G5.5a.1(transcript)|ensemblmetazoa:WBGene00011625(gene)|uniprotkb:Q1ZXS5(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/10/20 rogid:RNDp87iDe63C67Ef2THc2ppRDDY6239 rogid:bV95kVyB4dSQQ2UM4gm8+OlWfoU6239 intact-crc:5B75484258868B4D|rigid:WC32MWMMHFcx+mcKYT7675cJuSk false - sufficient binding region:526-923("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95008 uniprotkb:Q95005 intact:EBI-320441|ensemblmetazoa:F25H2.9.1 intact:EBI-316796|ensemblmetazoa:C36B1.4.1|ensemblmetazoa:C36B1.4.2 psi-mi:psa5_caeel(display_long)|uniprotkb:pas-5(gene name)|psi-mi:pas-5(display_short)|uniprotkb:F25H2.9(orf name) psi-mi:psa7_caeel(display_long)|uniprotkb:pas-4(gene name)|psi-mi:pas-4(display_short)|uniprotkb:C36B1.4(orf name)|uniprotkb:Proteasome subunit alpha 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457571|imex:IM-11985-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492765.1|wormbase:F25H2.9|ensemblmetazoa:F25H2.9.1(transcript)|ensemblmetazoa:WBGene00003926(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-6798695|reactome:R-CEL-5632684|dip:DIP-24675N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 reactome:R-CEL-5689603|reactome:R-CEL-5689880|refseq:NP_492360.1|wormbase:C36B1.4|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:C36B1.4.1(transcript)|ensemblmetazoa:C36B1.4.2(transcript)|ensemblmetazoa:WBGene00003925(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bCIpCQ1H7EOMauSeXBTk7dzlrTw6239 rogid:WWXt5jeuKRCX9WomT3Wqk45PRIc6239 intact-crc:DFFB1D0B4B48077D|rigid:3O4GukQbXou/B7zxybu3DzEEyUk false - sufficient binding region:5-253("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02365 uniprotkb:Q2V0X4 intact:EBI-322131|ensemblmetazoa:W10G6.3.1 intact:EBI-6456854 psi-mi:ifa2_caeel(display_long)|uniprotkb:mua-6(gene name)|psi-mi:mua-6(display_short)|uniprotkb:Cel IF A2(gene name synonym)|uniprotkb:Intermediate filament protein A2(gene name synonym)|uniprotkb:ifa-2(gene name synonym)|uniprotkb:W10G6.3(orf name) psi-mi:q2v0x4_caeel(display_long)|uniprotkb:cogc-3(gene name)|psi-mi:cogc-3(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457551|imex:IM-11985-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_510648.1|wormbase:W10G6.3|reactome:R-CEL-4419969|ensemblmetazoa:W10G6.3.1(transcript)|ensemblmetazoa:WBGene00003485(gene)|go:"GO:0005882"(intermediate filament)|go:"GO:0030056"(hemidesmosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR036415|interpro:IPR039008|dip:DIP-26450N go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007265(Sec34-like protein) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pdWSrp+seluBAT//FOdDkdlq7786239 rogid:G/tGsp4WwyIUGdFnfOzoBMkgOrM6239 intact-crc:F258DC924D220842|rigid:ocP/Y3BTwQyXIZS8STXoe2mo+y4 false sufficient binding region:52-581("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17979 uniprotkb:Q09436 intact:EBI-317575|ensemblmetazoa:C14C11.2.1|ensemblmetazoa:C14C11.2.2 intact:EBI-300562|ensemblmetazoa:AH6.5.1 psi-mi:q17979_caeel(display_long)|uniprotkb:C14C11.2(orf name)|uniprotkb:CELE_C14C11.2(orf name) psi-mi:mex6_caeel(display_long)|uniprotkb:mex-6(gene name)|psi-mi:mex-6(display_short)|uniprotkb:AH6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457561|imex:IM-11985-196 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504491.1|wormbase:C14C11.2|ensemblmetazoa:C14C11.2.1(transcript)|ensemblmetazoa:C14C11.2.2(transcript)|ensemblmetazoa:WBGene00015766(gene)|dip:DIP-25962N ensemblmetazoa:AH6.5.1(transcript)|ensemblmetazoa:WBGene00003231(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0005829"(cytosol)|refseq:NP_496043.1|wormbase:AH6.5|reactome:R-CEL-450385|dip:DIP-26165N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0E7xDeyfOOahXnabDt9VZez17TY6239 rogid:oVKWJRS2uVN3eOW+qihqknx3WJM6239 intact-crc:CDAB493FAADB4BD4|rigid:/Xc8AIxj9SU6raIoFgAi0E/7rq8 false sufficient binding region:52-574("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09583 uniprotkb:Q09583 intact:EBI-315406|ensemblmetazoa:ZK945.2.1|ensemblmetazoa:ZK945.2.2 intact:EBI-315406|ensemblmetazoa:ZK945.2.1|ensemblmetazoa:ZK945.2.2 psi-mi:psa3_caeel(display_long)|uniprotkb:pas-7(gene name)|psi-mi:pas-7(display_short)|uniprotkb:ZK945.2(orf name)|uniprotkb:Proteasome subunit alpha 7(gene name synonym) psi-mi:psa3_caeel(display_long)|uniprotkb:pas-7(gene name)|psi-mi:pas-7(display_short)|uniprotkb:ZK945.2(orf name)|uniprotkb:Proteasome subunit alpha 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457601|imex:IM-11985-200 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496177.2|wormbase:ZK945.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:WBGene00003928(gene)|ensemblmetazoa:ZK945.2.1(transcript)|ensemblmetazoa:ZK945.2.2(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|interpro:IPR037555|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 refseq:NP_496177.2|wormbase:ZK945.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:WBGene00003928(gene)|ensemblmetazoa:ZK945.2.1(transcript)|ensemblmetazoa:ZK945.2.2(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|interpro:IPR037555|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OOdurA40PpJd/0X3BA8Z5ZWqCuM6239 rogid:OOdurA40PpJd/0X3BA8Z5ZWqCuM6239 intact-crc:23BE5CC11591CE7C|rigid:r7iszOM/6eTWw/wJqfy7WmKMub0 false - sufficient binding region:5-250("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44156 uniprotkb:Q09583 intact:EBI-318264|ensemblmetazoa:CD4.6.1 intact:EBI-315406|ensemblmetazoa:ZK945.2.1|ensemblmetazoa:ZK945.2.2 psi-mi:psa1_caeel(display_long)|uniprotkb:pas-6(gene name)|psi-mi:pas-6(display_short)|uniprotkb:CD4.6(orf name)|uniprotkb:Proteasome subunit alpha 6(gene name synonym) psi-mi:psa3_caeel(display_long)|uniprotkb:pas-7(gene name)|psi-mi:pas-7(display_short)|uniprotkb:ZK945.2(orf name)|uniprotkb:Proteasome subunit alpha 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457581|imex:IM-11985-198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504472.1|wormbase:CD4.6|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:CD4.6.1(transcript)|ensemblmetazoa:WBGene00003927(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR035144|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_496177.2|wormbase:ZK945.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:WBGene00003928(gene)|ensemblmetazoa:ZK945.2.1(transcript)|ensemblmetazoa:ZK945.2.2(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|interpro:IPR037555|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:D/OFB0z6DBE6ohjjHkvLHgK9jCI6239 rogid:OOdurA40PpJd/0X3BA8Z5ZWqCuM6239 intact-crc:C527AD9D707EA499|rigid:BC67rxYKEdka+p+NICpehIhMNTo false - sufficient binding region:5-250("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09583 uniprotkb:Q20351 intact:EBI-315406|ensemblmetazoa:ZK945.2.1|ensemblmetazoa:ZK945.2.2 intact:EBI-2003656|uniprotkb:Q8T8N1|ensemblmetazoa:F42G9.8.1 psi-mi:psa3_caeel(display_long)|uniprotkb:pas-7(gene name)|psi-mi:pas-7(display_short)|uniprotkb:ZK945.2(orf name)|uniprotkb:Proteasome subunit alpha 7(gene name synonym) psi-mi:tpstb_caeel(display_long)|uniprotkb:Tyrosylprotein sulfotransferase(gene name synonym)|uniprotkb:F42G9.8(orf name)|uniprotkb:tpst-2(gene name)|psi-mi:tpst-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457591|imex:IM-11985-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496177.2|wormbase:ZK945.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:WBGene00003928(gene)|ensemblmetazoa:ZK945.2.1(transcript)|ensemblmetazoa:ZK945.2.2(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|interpro:IPR037555|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 refseq:NP_497256.1|wormbase:F42G9.8|interpro:IPR026634|interpro:IPR027417|ensemblmetazoa:F42G9.8.1(transcript)|ensemblmetazoa:WBGene00018365(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006478"(peptidyl-tyrosine sulfation)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0008476"(protein-tyrosine sulfotransferase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OOdurA40PpJd/0X3BA8Z5ZWqCuM6239 rogid:S6qylnnMtTn+mWQWGCSzFCCY4/s6239 intact-crc:C2851B2748CD2826|rigid:lCK18KntCRqYdir3ZItRJ/p9UyU false sufficient binding region:5-250("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TA83 uniprotkb:P91457 intact:EBI-331999|uniprotkb:P34408|uniprotkb:Q95QJ6|ensemblmetazoa:F22B7.5a.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:dnj10_caeel(display_long)|uniprotkb:F22B7.5(orf name)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457631|imex:IM-11985-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498901.1|refseq:NP_498902.1|wormbase:F22B7.5a|wormbase:F22B7.5b|dip:DIP-24664N|ensemblmetazoa:F22B7.5a.1(transcript)|ensemblmetazoa:WBGene00001028(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009408"(response to heat)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:rZSB2nN04hE44ryl282RwGo9QqQ6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:1F695051FA46E9FB|rigid:KRfm9TN9JQVzxxuDeEhTNrHhaGs false sufficient binding region:52-401("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TA83 uniprotkb:Q8TA83-2 intact:EBI-331999|uniprotkb:P34408|uniprotkb:Q95QJ6|ensemblmetazoa:F22B7.5a.1 intact:EBI-680063|ensemblmetazoa:F22B7.5b.1 psi-mi:dnj10_caeel(display_long)|uniprotkb:F22B7.5(orf name)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short) psi-mi:q8ta83-2(display_long)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:F22B7.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457611|imex:IM-11985-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498901.1|refseq:NP_498902.1|wormbase:F22B7.5a|wormbase:F22B7.5b|dip:DIP-24664N|ensemblmetazoa:F22B7.5a.1(transcript)|ensemblmetazoa:WBGene00001028(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009408"(response to heat)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 intact:EBI-331999(dnj10_caeel)|ensemblmetazoa:F22B7.5b.1(transcript)|ensemblmetazoa:WBGene00001028(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:rZSB2nN04hE44ryl282RwGo9QqQ6239 rogid:ZpgWCeAeWbLWXJuhUSVyjnUmraw6239 intact-crc:2E5CF63687F46DB2|rigid:v22vn3HrfTlXv9YS0gM6tmDCDPE false sufficient binding region:52-401("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XU12 uniprotkb:Q8TA83 intact:EBI-325126|ensemblmetazoa:K11D9.1a.1 intact:EBI-331999|uniprotkb:P34408|uniprotkb:Q95QJ6|ensemblmetazoa:F22B7.5a.1 psi-mi:q9xu12_caeel(display_long)|uniprotkb:klp-7(gene name)|psi-mi:klp-7(display_short)|uniprotkb:CELE_K11D9.1(orf name)|uniprotkb:K11D9.1(orf name) psi-mi:dnj10_caeel(display_long)|uniprotkb:F22B7.5(orf name)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457621|imex:IM-11985-202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022677.1|wormbase:K11D9.1a|ensemblmetazoa:K11D9.1a.1(transcript)|ensemblmetazoa:WBGene00002219(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010938"(cytoplasmic microtubule depolymerization)|go:"GO:0018991"(oviposition)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|dip:DIP-26934N|reactome:R-CEL-983189 refseq:NP_498901.1|refseq:NP_498902.1|wormbase:F22B7.5a|wormbase:F22B7.5b|dip:DIP-24664N|ensemblmetazoa:F22B7.5a.1(transcript)|ensemblmetazoa:WBGene00001028(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009408"(response to heat)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CHfEKYlTwlJs6zeaXZrs0KLrlSI6239 rogid:rZSB2nN04hE44ryl282RwGo9QqQ6239 intact-crc:6DE9FFF47C4D8638|rigid:uqTz1CYzAp/xsOVOe+La2RaaCbA false - sufficient binding region:52-401("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q27488 uniprotkb:O44156 intact:EBI-318271|ensemblmetazoa:D1054.2.1|ensemblmetazoa:D1054.2.2 intact:EBI-318264|ensemblmetazoa:CD4.6.1 psi-mi:psa2_caeel(display_long)|uniprotkb:pas-2(gene name)|psi-mi:pas-2(display_short)|uniprotkb:D1054.2(orf name) psi-mi:psa1_caeel(display_long)|uniprotkb:pas-6(gene name)|psi-mi:pas-6(display_short)|uniprotkb:CD4.6(orf name)|uniprotkb:Proteasome subunit alpha 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457671|imex:IM-11985-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505750.1|wormbase:D1054.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034644|reactome:R-CEL-5687128|interpro:IPR029055|reactome:R-CEL-187577|ensemblmetazoa:D1054.2.1(transcript)|ensemblmetazoa:D1054.2.2(transcript)|ensemblmetazoa:WBGene00003923(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_504472.1|wormbase:CD4.6|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:CD4.6.1(transcript)|ensemblmetazoa:WBGene00003927(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR035144|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oxMITWZNzWRcUpGSL6T7pKrm+Xs6239 rogid:D/OFB0z6DBE6ohjjHkvLHgK9jCI6239 intact-crc:44521552D6EC049C|rigid:BahDNsWfuTRX534jiKr8QAAunlQ false sufficient binding region:5-231("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49197 uniprotkb:P46769 intact:EBI-313268|ensemblmetazoa:F37C12.11.1 intact:EBI-313262|ensemblmetazoa:B0393.1.1|ensemblmetazoa:B0393.1.2 psi-mi:rs21_caeel(display_long)|uniprotkb:rps-21(gene name)|psi-mi:rps-21(display_short)|uniprotkb:F37C12.11(orf name) psi-mi:rssa_caeel(display_long)|uniprotkb:B0393.1(orf name)|uniprotkb:rps-0(gene name)|psi-mi:rps-0(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457641|imex:IM-11985-204 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498579.2|wormbase:F37C12.11|ensemblmetazoa:F37C12.11.1(transcript)|ensemblmetazoa:WBGene00004490(gene)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000461"("endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR001931(Ribosomal protein S21e)|interpro:IPR018279|interpro:IPR038579|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975957|reactome:R-CEL-72649|reactome:R-CEL-975956|dip:DIP-25541N refseq:NP_497978.1|wormbase:B0393.1|ensemblmetazoa:B0393.1.1(transcript)|ensemblmetazoa:B0393.1.2(transcript)|ensemblmetazoa:WBGene00004469(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975957|reactome:R-CEL-72649|reactome:R-CEL-975956|dip:DIP-26217N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ohoHPIQSeNMf2So+gKPi8ohMWSI6239 rogid:7tsgt7UcrNPsyTZQBzoRlcA/hvw6239 intact-crc:C11D8332909018BF|rigid:psK3DEGNRSU+WwFnxYiuNcEmMMs false - sufficient binding region:5-232("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4E9 uniprotkb:Q9XW79 intact:EBI-331766|ensemblmetazoa:Y71H2B.3.1 intact:EBI-331742|uniprotkb:Q966Q4|ensemblmetazoa:Y75B8A.30.1 psi-mi:pp4rs_caeel(display_long)|uniprotkb:ppfr-4(gene name)|psi-mi:ppfr-4(display_short)|uniprotkb:Y71H2B.3(orf name) psi-mi:pp4c1_caeel(display_long)|uniprotkb:pph-4.1(gene name)|psi-mi:pph-4.1(display_short)|uniprotkb:Y75B8A.30(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457651|imex:IM-11985-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497591.1|wormbase:Y71H2B.3|dip:DIP-27072N|ensemblmetazoa:WBGene00022193(gene)|ensemblmetazoa:Y71H2B.3.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511 refseq:NP_499603.1|wormbase:Y75B8A.30|dip:DIP-24807N|ensemblmetazoa:WBGene00004085(gene)|ensemblmetazoa:Y75B8A.30.1(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016311"(dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1905261"(regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:DmlEnJ9TsnA4eRRlzusNPoTeDy46239 rogid:2W4T4LTMeuxTZrZu2Y2gg7bUAXE6239 intact-crc:D6A921E51CBA3FBE|rigid:ZOY20JZO6twew3qL273PZ4UwG30 false sufficient binding region:5-232("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95005 uniprotkb:Q27488 intact:EBI-316796|ensemblmetazoa:C36B1.4.1|ensemblmetazoa:C36B1.4.2 intact:EBI-318271|ensemblmetazoa:D1054.2.1|ensemblmetazoa:D1054.2.2 psi-mi:psa7_caeel(display_long)|uniprotkb:pas-4(gene name)|psi-mi:pas-4(display_short)|uniprotkb:C36B1.4(orf name)|uniprotkb:Proteasome subunit alpha 4(gene name synonym) psi-mi:psa2_caeel(display_long)|uniprotkb:pas-2(gene name)|psi-mi:pas-2(display_short)|uniprotkb:D1054.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457661|imex:IM-11985-206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5689603|reactome:R-CEL-5689880|refseq:NP_492360.1|wormbase:C36B1.4|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:C36B1.4.1(transcript)|ensemblmetazoa:C36B1.4.2(transcript)|ensemblmetazoa:WBGene00003925(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_505750.1|wormbase:D1054.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034644|reactome:R-CEL-5687128|interpro:IPR029055|reactome:R-CEL-187577|ensemblmetazoa:D1054.2.1(transcript)|ensemblmetazoa:D1054.2.2(transcript)|ensemblmetazoa:WBGene00003923(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WWXt5jeuKRCX9WomT3Wqk45PRIc6239 rogid:oxMITWZNzWRcUpGSL6T7pKrm+Xs6239 intact-crc:E13644ED03EF8220|rigid:ORMzlDIfTbUazv7yYHY59fMpvio false - sufficient binding region:5-231("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91303 uniprotkb:Q95X44 intact:EBI-2003781|ensemblmetazoa:F46F11.5.1|ensemblmetazoa:F46F11.5.2 intact:EBI-320484|ensemblmetazoa:C17H12.14.1 psi-mi:vatg_caeel(display_long)|uniprotkb:vha-10(gene name)|psi-mi:vha-10(display_short)|uniprotkb:Vacuolar proton pump subunit G(gene name synonym)|uniprotkb:F46F11.5(orf name) psi-mi:q95x44_caeel(display_long)|uniprotkb:vha-8(gene name)|psi-mi:vha-8(display_short)|uniprotkb:CELE_C17H12.14(orf name)|uniprotkb:C17H12.14(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457701|imex:IM-11985-210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491641.1|wormbase:F46F11.5|interpro:IPR005124("Vacuolar (H+)-ATPase G subunit")|reactome:R-CEL-77387|reactome:R-CEL-1222556|reactome:R-CEL-9639288|reactome:R-CEL-917977|reactome:R-CEL-983712|ensemblmetazoa:F46F11.5.1(transcript)|ensemblmetazoa:F46F11.5.2(transcript)|ensemblmetazoa:WBGene00006919(gene)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:1902600"(proton transmembrane transport) refseq:NP_501040.1|wormbase:C17H12.14|ensemblmetazoa:C17H12.14.1(transcript)|ensemblmetazoa:WBGene00006917(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|interpro:IPR038495|reactome:R-CEL-1222556|reactome:R-CEL-77387|dip:DIP-24784N|reactome:R-CEL-917977|reactome:R-CEL-983712|reactome:R-CEL-9639288 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OMpOGFcK/AAhQmddyXeqyfPQ48k6239 rogid:mBB4i2zR6qIyGppEueZ3Gi9v+2w6239 intact-crc:877A256402551F03|rigid:QZcPnzWhUrwP8xztdtP0Vj/xyKo false - sufficient binding region:5-226("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q27488 uniprotkb:Q27488 intact:EBI-318271|ensemblmetazoa:D1054.2.1|ensemblmetazoa:D1054.2.2 intact:EBI-318271|ensemblmetazoa:D1054.2.1|ensemblmetazoa:D1054.2.2 psi-mi:psa2_caeel(display_long)|uniprotkb:pas-2(gene name)|psi-mi:pas-2(display_short)|uniprotkb:D1054.2(orf name) psi-mi:psa2_caeel(display_long)|uniprotkb:pas-2(gene name)|psi-mi:pas-2(display_short)|uniprotkb:D1054.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457681|imex:IM-11985-208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505750.1|wormbase:D1054.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034644|reactome:R-CEL-5687128|interpro:IPR029055|reactome:R-CEL-187577|ensemblmetazoa:D1054.2.1(transcript)|ensemblmetazoa:D1054.2.2(transcript)|ensemblmetazoa:WBGene00003923(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_505750.1|wormbase:D1054.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034644|reactome:R-CEL-5687128|interpro:IPR029055|reactome:R-CEL-187577|ensemblmetazoa:D1054.2.1(transcript)|ensemblmetazoa:D1054.2.2(transcript)|ensemblmetazoa:WBGene00003923(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oxMITWZNzWRcUpGSL6T7pKrm+Xs6239 rogid:oxMITWZNzWRcUpGSL6T7pKrm+Xs6239 intact-crc:260ADA9CAFAAD639|rigid:WTihNYFgti4+8hgGbnPDi1cpPEA false sufficient binding region:5-231("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94392 uniprotkb:Q27488 intact:EBI-316816|ensemblmetazoa:H15N14.2a.1 intact:EBI-318271|ensemblmetazoa:D1054.2.1|ensemblmetazoa:D1054.2.2 psi-mi:nsf_caeel(display_long)|uniprotkb:H15N14.2(orf name)|uniprotkb:nsf-1(gene name)|psi-mi:nsf-1(display_short)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym) psi-mi:psa2_caeel(display_long)|uniprotkb:pas-2(gene name)|psi-mi:pas-2(display_short)|uniprotkb:D1054.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457691|imex:IM-11985-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6807878|reactome:R-CEL-204005|refseq:NP_001076603.1|wormbase:H15N14.2a|reactome:R-CEL-6811438|reactome:R-CEL-6811440|ensemblmetazoa:H15N14.2a.1(transcript)|ensemblmetazoa:WBGene00003818(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005795"(Golgi stack)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|dip:DIP-24326N|reactome:R-CEL-6811434 refseq:NP_505750.1|wormbase:D1054.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034644|reactome:R-CEL-5687128|interpro:IPR029055|reactome:R-CEL-187577|ensemblmetazoa:D1054.2.1(transcript)|ensemblmetazoa:D1054.2.2(transcript)|ensemblmetazoa:WBGene00003923(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aRp2HvXAWW2KJuimcz+d4XfBEVI6239 rogid:oxMITWZNzWRcUpGSL6T7pKrm+Xs6239 intact-crc:DAC68DC74D5EBB3D|rigid:VxP26g7ZZpjsosu1HkgkiacTBNk false - sufficient binding region:5-231("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34808 uniprotkb:O44740 intact:EBI-323248|intact:EBI-521368|uniprotkb:Q8I4G6|ensemblmetazoa:T01G9.5a.1 intact:EBI-323243|ensemblmetazoa:F57B10.12.1 psi-mi:ktna1_caeel(display_long)|uniprotkb:mei-1(gene name)|psi-mi:mei-1(display_short)|uniprotkb:Katanin p60 ATPase-containing subunit A1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:T01G9.5(orf name) psi-mi:mei2_caeel(display_long)|uniprotkb:mei-2(gene name)|psi-mi:mei-2(display_short)|uniprotkb:F57B10.12(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457741|imex:IM-11985-214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492257.1|refseq:NP_871793.1|wormbase:T01G9.5a|wormbase:T01G9.5b|ensemblmetazoa:T01G9.5a.1(transcript)|ensemblmetazoa:WBGene00003183(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000785"(chromatin)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051013"(microtubule severing)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0005813"(centrosome)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0090736"(MATH domain binding)|go:"GO:1902120"(negative regulation of meiotic spindle elongation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR028596|interpro:IPR041569|rcsb pdb:5WC0|rcsb pdb:5WC1|rcsb pdb:5WCB|rcsb pdb:6B5D|go:"GO:0005819"(spindle)|rcsb pdb:6UGD|rcsb pdb:6UGE|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|rcsb pdb:6UGF|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008017"(microtubule binding)|go:"GO:0008352"(katanin complex)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|dip:DIP-25343N refseq:NP_491894.1|wormbase:F57B10.12|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008352"(katanin complex)|ensemblmetazoa:F57B10.12.1(transcript)|ensemblmetazoa:WBGene00003184(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001940"(male pronucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051013"(microtubule severing)|go:"GO:0051301"(cell division)|interpro:IPR028021|dip:DIP-27215N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W8dzUByepgfcMfSsWiLQdK+/pus6239 rogid:HkLWJzdRNw3NMipE4Q42A4cT7ks6239 intact-crc:170CAA58ECF123B8|rigid:vzxBsu4jJ8pZCX+WflSL9sgsDIk false sufficient binding region:5-194("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17915 uniprotkb:Q21021 intact:EBI-324099|ensemblmetazoa:K01G5.4.1 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 psi-mi:ran_caeel(display_long)|uniprotkb:ran-1(gene name)|psi-mi:ran-1(display_short)|uniprotkb:K01G5.4(orf name)|uniprotkb:Ras-related nuclear protein 1(gene name synonym) psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457711|imex:IM-11985-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499369.1|wormbase:K01G5.4|ensemblmetazoa:K01G5.4.1(transcript)|ensemblmetazoa:WBGene00004302(gene)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CEL-1655829|dip:DIP-25217N|reactome:R-CEL-9615933 refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:yo75CoWqaTF5xYXAujyoTXXvRw86239 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 intact-crc:5EC76379714E599C|rigid:fyKnoNfHQd8QDN2YB9ieWLprel4 false sufficient binding region:5-215("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23237 uniprotkb:O62102 intact:EBI-314040|ensemblmetazoa:Y38A8.2.1 intact:EBI-317386|ensemblmetazoa:C47B2.4.1 psi-mi:psb3_caeel(display_long)|uniprotkb:pbs-3(gene name)|psi-mi:pbs-3(display_short)|uniprotkb:Y38A8.2(orf name) psi-mi:o62102_caeel(display_long)|uniprotkb:pbs-2(gene name)|psi-mi:pbs-2(display_short)|uniprotkb:C47B2.4(orf name)|uniprotkb:CELE_C47B2.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457721|imex:IM-11985-212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8932339|refseq:NP_494913.1|wormbase:Y38A8.2|reactome:R-CEL-5632684|ensemblmetazoa:WBGene00003949(gene)|ensemblmetazoa:Y38A8.2.1(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-25063N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 reactome:R-CEL-187577|refseq:NP_493271.1|wormbase:C47B2.4|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023333|interpro:IPR029055|ensemblmetazoa:C47B2.4.1(transcript)|ensemblmetazoa:WBGene00003948(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5632684|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-6798695|reactome:R-CEL-8932339|reactome:R-CEL-68949|interpro:IPR035216|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XDQsAOH8E9LxVDloQ25KGEoFB6c6239 rogid:eg9h7mVfM8t5rvzr+jiN2fsj8Tw6239 intact-crc:27D15B7AA39B9DC8|rigid:Rg2WYsxbobHOW9d85j0Sz4/WWHc false sufficient binding region:5-204("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20168 uniprotkb:Q9XW17 intact:EBI-895887|ensemblmetazoa:F38E11.5.1 intact:EBI-329782|ensemblmetazoa:Y18D10A.17.1 psi-mi:copb2_caeel(display_long)|uniprotkb:copb-2(gene name)|psi-mi:copb-2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:F38E11.5(orf name) psi-mi:q9xw17_caeel(display_long)|uniprotkb:car-1(gene name)|psi-mi:car-1(display_short)|uniprotkb:Y18D10A.17(orf name)|uniprotkb:CELE_Y18D10A.17(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457731|imex:IM-11985-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501671.1|wormbase:F38E11.5|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|reactome:R-CEL-6807878|reactome:R-CEL-6811434|ensemblmetazoa:F38E11.5.1(transcript)|ensemblmetazoa:WBGene00009542(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048599"(oocyte development) refseq:NP_493254.1|wormbase:Y18D10A.17|dip:DIP-26312N|ensemblmetazoa:WBGene00012484(gene)|ensemblmetazoa:Y18D10A.17.1(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000932"(P-body)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043186"(P granule)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|go:"GO:0072686"(mitotic spindle)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|rcsb pdb:6F9S psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:3SJ6S3Htfpx07drbV+B3WtohNNs6239 rogid:DnydGOElf2VvxV3JEWypoxJq60c6239 intact-crc:D106F6DA13AAB575|rigid:t9YBgv0TwIANbuC/yZN0NNWQ1Js false - sufficient binding region:5-202("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDD8 uniprotkb:Q18255 intact:EBI-314583|ensemblmetazoa:F46A9.4.1 intact:EBI-314520|ensemblmetazoa:C27D9.1.1 psi-mi:g5edd8_caeel(display_long)|uniprotkb:skr-2(gene name)|psi-mi:skr-2(display_short)|uniprotkb:CELE_F46A9.4(orf name)|uniprotkb:F46A9.4(orf name) psi-mi:q18255_caeel(display_long)|uniprotkb:C27D9.1(orf name)|uniprotkb:CELE_C27D9.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457771|imex:IM-11985-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q93731(uniprot-removed-ac)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492512.1|wormbase:F46A9.4|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0097602"(cullin family protein binding)|ensemblmetazoa:F46A9.4.1(transcript)|ensemblmetazoa:WBGene00004808(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|interpro:IPR036296 interpro:IPR009497(Protein of unknown function DUF1114)|wormbase:C27D9.1|refseq:NP_494851.2|ensemblmetazoa:C27D9.1.1(transcript)|ensemblmetazoa:WBGene00016163(gene)|go:"GO:0006486"(protein glycosylation)|go:"GO:0016020"(membrane)|go:"GO:0036065"(fucosylation)|go:"GO:0046920"("alpha-(1->3)-fucosyltransferase activity")|interpro:IPR001503(Glycosyl transferase, family 10)|reactome:R-CEL-9037629|reactome:R-CEL-975578 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:j2g9jI5SVR7+s5r1E3Pk+j/4lgo6239 rogid:2CAJcTLTMmwKH9AtJ6AH8xQxGK06239 intact-crc:04D222A819F61F15|rigid:+H/4DwbIia07JW8/TpElysnKW7w false sufficient binding region:5-174("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECU1 uniprotkb:G5EGT6 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 intact:EBI-323609|ensemblmetazoa:H02I12.8.1 psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:g5egt6_caeel(display_long)|uniprotkb:cyp-31a2(gene name)|psi-mi:cyp-31a2(display_short)|uniprotkb:cyp-31A2(gene name synonym)|uniprotkb:H02I12.8(orf name)|uniprotkb:CELE_H02I12.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457761|imex:IM-11985-216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 wormbase:H02I12.8|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|refseq:NP_502152.3|uniprotkb:O45605(uniprot-removed-ac)|ensemblmetazoa:H02I12.8.1(transcript)|ensemblmetazoa:WBGene00010354(gene)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0030703"(eggshell formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0048598"(embryonic morphogenesis)|interpro:IPR036396|reactome:R-CEL-193144|reactome:R-CEL-196791|reactome:R-CEL-211916|reactome:R-CEL-211976|reactome:R-CEL-211935|reactome:R-CEL-211958|reactome:R-CEL-211979|reactome:R-CEL-2142691|reactome:R-CEL-2142816 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 rogid:rFBca9MqzVl/AAexNGFIAdU82t06239 intact-crc:D0AC5D36F4656C6D|rigid:PteuC8J7pH4+MsQFZ+iqpWwAY2Y false sufficient binding region:5-176("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECU1 uniprotkb:Q18255 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 intact:EBI-314520|ensemblmetazoa:C27D9.1.1 psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:q18255_caeel(display_long)|uniprotkb:C27D9.1(orf name)|uniprotkb:CELE_C27D9.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457751|imex:IM-11985-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 interpro:IPR009497(Protein of unknown function DUF1114)|wormbase:C27D9.1|refseq:NP_494851.2|ensemblmetazoa:C27D9.1.1(transcript)|ensemblmetazoa:WBGene00016163(gene)|go:"GO:0006486"(protein glycosylation)|go:"GO:0016020"(membrane)|go:"GO:0036065"(fucosylation)|go:"GO:0046920"("alpha-(1->3)-fucosyltransferase activity")|interpro:IPR001503(Glycosyl transferase, family 10)|reactome:R-CEL-9037629|reactome:R-CEL-975578 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 rogid:2CAJcTLTMmwKH9AtJ6AH8xQxGK06239 intact-crc:6BF53D75C2BBA96D|rigid:GNzvLSyuPWEU08o7EANlOtNX5sg false sufficient binding region:5-176("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09436 uniprotkb:Q09436 intact:EBI-300562|ensemblmetazoa:AH6.5.1 intact:EBI-300562|ensemblmetazoa:AH6.5.1 psi-mi:mex6_caeel(display_long)|uniprotkb:mex-6(gene name)|psi-mi:mex-6(display_short)|uniprotkb:AH6.5(orf name) psi-mi:mex6_caeel(display_long)|uniprotkb:mex-6(gene name)|psi-mi:mex-6(display_short)|uniprotkb:AH6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457801|imex:IM-11985-220 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:AH6.5.1(transcript)|ensemblmetazoa:WBGene00003231(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0005829"(cytosol)|refseq:NP_496043.1|wormbase:AH6.5|reactome:R-CEL-450385|dip:DIP-26165N ensemblmetazoa:AH6.5.1(transcript)|ensemblmetazoa:WBGene00003231(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0005829"(cytosol)|refseq:NP_496043.1|wormbase:AH6.5|reactome:R-CEL-450385|dip:DIP-26165N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oVKWJRS2uVN3eOW+qihqknx3WJM6239 rogid:oVKWJRS2uVN3eOW+qihqknx3WJM6239 intact-crc:73CC6EA59DF2D319|rigid:lXbq8zxFn+KgNq+a8FlLuc9zfZ8 false sufficient binding region:51-437("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23670 uniprotkb:Q21993 intact:EBI-323996|uniprotkb:Q27509|ensemblmetazoa:K12D12.1.1 intact:EBI-323701|ensemblmetazoa:R151.9.1 psi-mi:top2_caeel(display_long)|uniprotkb:top-2(gene name)|psi-mi:top-2(display_short)|uniprotkb:DNA topoisomerase II(gene name synonym)|uniprotkb:K12D12.1(orf name) psi-mi:pfd5_caeel(display_long)|uniprotkb:R151.9(orf name)|uniprotkb:pfd-5(gene name)|psi-mi:pfd-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457781|imex:IM-11985-218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496536.1|wormbase:K12D12.1|ensemblmetazoa:K12D12.1.1(transcript)|ensemblmetazoa:WBGene00010785(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006265"(DNA topological change)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR034157|interpro:IPR036890|interpro:IPR031660|reactome:R-CEL-4615885|dip:DIP-27416N refseq:NP_498582.1|wormbase:R151.9|ensemblmetazoa:WBGene00020112(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|ensemblmetazoa:R151.9.1(transcript)|dip:DIP-25712N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mMVe6/tBKCkNlRfJ3X08lsDKthg6239 rogid:vpZze2rqh9a2h5G80I7F5Xn2Css6239 intact-crc:2F5A2662C5945A76|rigid:P/N9iP9/9JoMsS0d7dDIO/4XYk4 false - sufficient binding region:5-152("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34342-1 uniprotkb:Q19969 intact:EBI-6456879|ensemblmetazoa:C29E4.3a.1 intact:EBI-317340|uniprotkb:O44925|ensemblmetazoa:F32E10.4.1 psi-mi:p34342-1(display_long)|uniprotkb:RanGAP(gene name synonym)|uniprotkb:C29E4.3(orf name)|uniprotkb:Ran nuclear import/export-related protein 2(gene name synonym)|uniprotkb:ran-2(gene name)|psi-mi:ran-2(display_short) psi-mi:ima3_caeel(display_long)|uniprotkb:ima-3(gene name)|psi-mi:ima-3(display_short)|uniprotkb:F32E10.4(orf name)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457791|imex:IM-11985-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C29E4.3a.1(transcript)|ensemblmetazoa:WBGene00004303(gene)|intact:EBI-6499769(isoform-parent) refseq:NP_501227.1|wormbase:F32E10.4|ensemblmetazoa:F32E10.4.1(transcript)|ensemblmetazoa:WBGene00002074(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007127"(meiosis I)|go:"GO:0007276"(gamete generation)|go:"GO:0007292"(female gamete generation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|dip:DIP-26417N psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:1uQylfSmaggjWNAEbOKcvb6nj/c6239 rogid:WT7vezZFUUJSBWKoQXOmUoUD+xc6239 intact-crc:55881A3C6D5471E5|rigid:pchDHaNZWZpYxiXvW/fZSSa/q70 false - sufficient binding region:51-445("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91482 uniprotkb:Q11183 intact:EBI-315371|ensemblmetazoa:T20F5.6.1 intact:EBI-2002064|ensemblmetazoa:C05D11.3.1 psi-mi:p91482_caeel(display_long)|uniprotkb:T20F5.6(orf name)|uniprotkb:CELE_T20F5.6(orf name) psi-mi:txnd9_caeel(display_long)|uniprotkb:txdc-9(gene name)|psi-mi:txdc-9(display_short)|uniprotkb:tag-170(gene name synonym)|uniprotkb:C05D11.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457836|imex:IM-11985-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491266.1|wormbase:T20F5.6|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|ensemblmetazoa:T20F5.6.1(transcript)|ensemblmetazoa:WBGene00020628(gene)|go:"GO:0046872"(metal ion binding) refseq:NP_498410.1|wormbase:C05D11.3|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|ensemblmetazoa:C05D11.3.1(transcript)|ensemblmetazoa:WBGene00006515(gene)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XgUfhY6bbYdTU31B8yVQiDR2+KA6239 rogid:/4qbqIRbra8evDuEO3f+4tYzVH06239 intact-crc:4E6DA5C161D98F65|rigid:wz+iGJqhVsJUmYAuLXrbZyjDx14 false sufficient binding region:513-794("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6457133 uniprotkb:Q6BEV5 intact:EBI-6306363 intact:EBI-2002318|intact:EBI-2923757|intact:EBI-2924015|ensemblmetazoa:R06F6.12.1 psi-mi:ebi6306363(display_short)|psi-mi:EBI-6457133(display_long)|intact:F39H11.2x(author assigned name) psi-mi:yrmc_caeel(display_long)|uniprotkb:R06F6.12(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457811|imex:IM-11985-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001022277.1|wormbase:R06F6.12|ensemblmetazoa:R06F6.12.1(transcript)|ensemblmetazoa:WBGene00023418(gene) psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:jP7TZCce2muoY78Ruk/qCSELK5M6239 intact-crc:56F62405A8BC70C1 false - sufficient binding region:51-417("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01501-1 uniprotkb:G5EEG9 intact:EBI-6457824|ensemblmetazoa:C37A2.4a.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:o01501-1(display_long)|uniprotkb:C37A2.4(orf name)|uniprotkb:cye-1(gene name)|psi-mi:cye-1(display_short) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457821|imex:IM-11985-222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C37A2.4a.1(transcript)|ensemblmetazoa:WBGene00000871(gene)|intact:EBI-6499833(isoform-parent) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:THl5Hcv1lfLuT3xEXRZhEQm1+886239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:D6F19C5B9597BF3F|rigid:4jrlUxdsK/l9t29z9jKSJ3g9xJ8 false - sufficient binding region:51-399("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P20163 uniprotkb:P46550 intact:EBI-327420|uniprotkb:O02085|ensemblmetazoa:F43E2.8a.1|ensemblmetazoa:F43E2.8a.2 intact:EBI-2007049|ensemblmetazoa:F01F1.8a.1|ensemblmetazoa:F01F1.8a.2 psi-mi:bibh_caeel(display_long)|uniprotkb:hsp-4(gene name)|psi-mi:hsp-4(display_short)|uniprotkb:hsp70d(gene name synonym)|uniprotkb:F43E2.8(orf name)|uniprotkb:Heat shock 70 kDa protein D(gene name synonym) psi-mi:tcpz_caeel(display_long)|uniprotkb:cct-6(gene name)|psi-mi:cct-6(display_short)|uniprotkb:CCT-zeta(gene name synonym)|uniprotkb:F01F1.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457866|imex:IM-11985-226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495536.1|wormbase:F43E2.8a|ensemblmetazoa:F43E2.8a.1(transcript)|ensemblmetazoa:F43E2.8a.2(transcript)|ensemblmetazoa:WBGene00002008(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|rcsb pdb:2OP6|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|dip:DIP-26704N interpro:IPR027410|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|reactome:R-CEL-390471|reactome:R-CEL-6814122|refseq:NP_741153.1|wormbase:F01F1.8a|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR027409|interpro:IPR027413|ensemblmetazoa:F01F1.8a.1(transcript)|ensemblmetazoa:F01F1.8a.2(transcript)|ensemblmetazoa:WBGene00000381(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:1OTImKHWwZAUWM6xI9ePrkRSAks6239 rogid:kn1OW8zNtUYRKCirQKY/Ofad6v86239 intact-crc:6F3081065DDAEFB0|rigid:1Pgjou+NJKEhkYtP09dGzbGb3N4 false - sufficient binding region:51-204("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q966L6 uniprotkb:G5EBE3 intact:EBI-2002434|ensemblmetazoa:E01A2.4.1|ensemblmetazoa:E01A2.4.2 intact:EBI-2003873|ensemblmetazoa:F55F8.4.1|ensemblmetazoa:F55F8.4.2 psi-mi:q966l6_caeel(display_long)|uniprotkb:let-504(gene name)|psi-mi:let-504(display_short)|uniprotkb:E01A2.4(orf name)|uniprotkb:CELE_E01A2.4(orf name) psi-mi:g5ebe3_caeel(display_long)|uniprotkb:cir-1(gene name)|psi-mi:cir-1(display_short)|uniprotkb:CELE_F55F8.4(orf name)|uniprotkb:F55F8.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457846|imex:IM-11985-224 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009269(Protein of unknown function DUF926)|refseq:NP_491301.1|wormbase:E01A2.4|interpro:IPR040466|ensemblmetazoa:E01A2.4.1(transcript)|ensemblmetazoa:E01A2.4.2(transcript)|ensemblmetazoa:WBGene00002696(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression) uniprotkb:P91342(uniprot-removed-ac)|interpro:IPR040014|interpro:IPR019339|refseq:NP_491654.1|wormbase:F55F8.4|ensemblmetazoa:F55F8.4.1(transcript)|ensemblmetazoa:F55F8.4.2(transcript)|ensemblmetazoa:WBGene00018892(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:uFgJEqUfLjbmqnMplarxE6vk+Ck6239 rogid:WLmi45oz5gYwR5X4PaJ9/kUom1o6239 intact-crc:6C817CE488B91443|rigid:MBl7Z6PZC9EvGvZCttZwRrTYq4Q false sufficient binding region:51-353("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5V3 uniprotkb:Q20010 intact:EBI-320898|ensemblmetazoa:C53D5.6.1 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 psi-mi:q9n5v3_caeel(display_long)|uniprotkb:imb-3(gene name)|psi-mi:imb-3(display_short)|uniprotkb:CELE_C53D5.6(orf name)|uniprotkb:C53D5.6(orf name) psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457856|imex:IM-11985-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490715.1|wormbase:C53D5.6|ensemblmetazoa:C53D5.6.1(transcript)|ensemblmetazoa:WBGene00002077(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|interpro:IPR041389|interpro:IPR041653|dip:DIP-26917N refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+DZB8n7UfeEeXcLYSkOaYJ0YUNI6239 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 intact-crc:1AC0024511431909|rigid:S7MXJIGLHTN7vF9eSlMQ8vtjZFM false - sufficient binding region:51-301("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5V3 uniprotkb:Q9XWK3 intact:EBI-320898|ensemblmetazoa:C53D5.6.1 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 psi-mi:q9n5v3_caeel(display_long)|uniprotkb:imb-3(gene name)|psi-mi:imb-3(display_short)|uniprotkb:CELE_C53D5.6(orf name)|uniprotkb:C53D5.6(orf name) psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457876|imex:IM-11985-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490715.1|wormbase:C53D5.6|ensemblmetazoa:C53D5.6.1(transcript)|ensemblmetazoa:WBGene00002077(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|interpro:IPR041389|interpro:IPR041653|dip:DIP-26917N refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+DZB8n7UfeEeXcLYSkOaYJ0YUNI6239 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 intact-crc:6CD200AEC750BB68|rigid:2Jq5FDYZiX4uHR+9B9xNWZn3Ws0 false - sufficient binding region:51-201("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BKS1 uniprotkb:G5ECR7 intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1 intact:EBI-330567|ensemblmetazoa:Y41C4A.10.1 psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name) psi-mi:g5ecr7_caeel(display_long)|uniprotkb:3L686(gene name synonym)|uniprotkb:elb-1(gene name)|psi-mi:elb-1(display_short)|uniprotkb:Y41C4A.10(orf name)|uniprotkb:CELE_Y41C4A.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457886|imex:IM-11985-228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N uniprotkb:Q9XWU4(uniprot-removed-ac)|refseq:NP_499517.1|reactome:R-CEL-674695|reactome:R-CEL-6796648|wormbase:Y41C4A.10|interpro:IPR039049|interpro:IPR029071|reactome:R-CEL-1234176|reactome:R-CEL-983168|reactome:R-CEL-8951664|ensemblmetazoa:WBGene00001235(gene)|ensemblmetazoa:Y41C4A.10.1(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|reactome:R-CEL-75955|reactome:R-CEL-112382 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239 rogid:nd6q1xH1t5OIdfLT3hHtTS3gTqU6239 intact-crc:228F801DA406266F|rigid:5RYNpxrxzTZrh9A5wAfdEXUt04I false - sufficient binding region:5-118("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18255 uniprotkb:G5ECU1 intact:EBI-314520|ensemblmetazoa:C27D9.1.1 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 psi-mi:q18255_caeel(display_long)|uniprotkb:C27D9.1(orf name)|uniprotkb:CELE_C27D9.1(orf name) psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457916|imex:IM-11985-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009497(Protein of unknown function DUF1114)|wormbase:C27D9.1|refseq:NP_494851.2|ensemblmetazoa:C27D9.1.1(transcript)|ensemblmetazoa:WBGene00016163(gene)|go:"GO:0006486"(protein glycosylation)|go:"GO:0016020"(membrane)|go:"GO:0036065"(fucosylation)|go:"GO:0046920"("alpha-(1->3)-fucosyltransferase activity")|interpro:IPR001503(Glycosyl transferase, family 10)|reactome:R-CEL-9037629|reactome:R-CEL-975578 interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:2CAJcTLTMmwKH9AtJ6AH8xQxGK06239 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 intact-crc:FBF75F1A78BC7F88|rigid:GNzvLSyuPWEU08o7EANlOtNX5sg false sufficient binding region:5-101("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02108 uniprotkb:Q9TVL3 intact:EBI-329675|ensemblmetazoa:W08F4.8a.1 intact:EBI-2004141|uniprotkb:Q9XTH5|ensemblmetazoa:H25P06.2b.1 psi-mi:cdc37_caeel(display_long)|uniprotkb:W08F4.8(orf name)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division cycle-related protein 37(gene name synonym)|uniprotkb:cdc-37(gene name)|psi-mi:cdc-37(display_short) psi-mi:cdk9_caeel(display_long)|uniprotkb:cdk-9(gene name)|psi-mi:cdk-9(display_short)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:H25P06.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457896|imex:IM-11985-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001040820.1|wormbase:W08F4.8a|reactome:R-CEL-114608|dip:DIP-25193N|ensemblmetazoa:W08F4.8a.1(transcript)|ensemblmetazoa:WBGene00021097(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-CEL-8863795|reactome:R-CEL-9652282|reactome:R-CEL-5675482 reactome:R-CEL-9018519|refseq:NP_492906.2|refseq:NP_492907.2|wormbase:H25P06.2a|wormbase:H25P06.2b|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-CEL-674695|reactome:R-CEL-75955|reactome:R-CEL-6796648|reactome:R-CEL-6807505|reactome:R-CEL-112382|reactome:R-CEL-2173796|ensemblmetazoa:H25P06.2b.1(transcript)|ensemblmetazoa:WBGene00000410(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007281"(germ cell development)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016592"(mediator complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2001253"(regulation of histone H3-K36 trimethylation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BGPUAjBwpp1jT1o4miWT7nTRwus6239 rogid:XKhjFrQeV0F116KJvfjHvqeijvE6239 intact-crc:145E15C494375D0E|rigid:xcI86rJLrPSKboAKyQBQD5Dnieg false - sufficient binding region:51-140("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18255 uniprotkb:G5EDD8 intact:EBI-314520|ensemblmetazoa:C27D9.1.1 intact:EBI-314583|ensemblmetazoa:F46A9.4.1 psi-mi:q18255_caeel(display_long)|uniprotkb:C27D9.1(orf name)|uniprotkb:CELE_C27D9.1(orf name) psi-mi:g5edd8_caeel(display_long)|uniprotkb:skr-2(gene name)|psi-mi:skr-2(display_short)|uniprotkb:CELE_F46A9.4(orf name)|uniprotkb:F46A9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457906|imex:IM-11985-230 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009497(Protein of unknown function DUF1114)|wormbase:C27D9.1|refseq:NP_494851.2|ensemblmetazoa:C27D9.1.1(transcript)|ensemblmetazoa:WBGene00016163(gene)|go:"GO:0006486"(protein glycosylation)|go:"GO:0016020"(membrane)|go:"GO:0036065"(fucosylation)|go:"GO:0046920"("alpha-(1->3)-fucosyltransferase activity")|interpro:IPR001503(Glycosyl transferase, family 10)|reactome:R-CEL-9037629|reactome:R-CEL-975578 uniprotkb:Q93731(uniprot-removed-ac)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492512.1|wormbase:F46A9.4|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0097602"(cullin family protein binding)|ensemblmetazoa:F46A9.4.1(transcript)|ensemblmetazoa:WBGene00004808(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|interpro:IPR036296 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:2CAJcTLTMmwKH9AtJ6AH8xQxGK06239 rogid:j2g9jI5SVR7+s5r1E3Pk+j/4lgo6239 intact-crc:5E77D458D4A49CD3|rigid:+H/4DwbIia07JW8/TpElysnKW7w false sufficient binding region:5-101("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDE7 uniprotkb:G5EDL3 intact:EBI-324390|ensemblmetazoa:Y39G10AR.12a.1 intact:EBI-324340|ensemblmetazoa:K07C11.2.1|ensemblmetazoa:K07C11.2.2 psi-mi:g5ede7_caeel(display_long)|uniprotkb:tpxl-1(gene name)|psi-mi:tpxl-1(display_short)|uniprotkb:Y39G10AR.12(orf name)|uniprotkb:1C866(orf name)|uniprotkb:CELE_Y39G10AR.12(orf name) psi-mi:g5edl3_caeel(display_long)|uniprotkb:AIR-1(gene name synonym)|uniprotkb:air-1(gene name)|psi-mi:air-1(display_short)|uniprotkb:K07C11.2(orf name)|uniprotkb:CELE_K07C11.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457926|imex:IM-11985-232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740805.1|uniprotkb:Q95XR5(uniprot-removed-ac)|wormbase:Y39G10AR.12a|ensemblmetazoa:WBGene00021470(gene)|go:"GO:0000235"(astral microtubule)|ensemblmetazoa:Y39G10AR.12a.1(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly) uniprotkb:Q21271(uniprot-removed-ac)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_505119.1|wormbase:K07C11.2|interpro:IPR030616|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904781"(positive regulation of protein localization to centrosome)|ensemblmetazoa:K07C11.2.1(transcript)|ensemblmetazoa:K07C11.2.2(transcript)|ensemblmetazoa:WBGene00000098(gene)|go:"GO:0000235"(astral microtubule) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:L8qyImbTKWJWTK7yRTb2pY3sJ1s6239 rogid:WWa/rjtXe6RruL7Ui72IJ5OJXxw6239 intact-crc:293B553A835C1C74|rigid:bK0kpZh12QZOCeRU2FFWfMEJbT0 false sufficient binding region:5-101("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E0R7K7 uniprotkb:P91918 intact:EBI-6457956|ensemblmetazoa:Y59A8B.10b.1 intact:EBI-895974|ensemblmetazoa:W08E3.1.1 psi-mi:e0r7k7_caeel(display_long)|uniprotkb:nova-1(gene name)|psi-mi:nova-1(display_short)|uniprotkb:CELE_Y59A8B.10(orf name)|uniprotkb:Y59A8B.10(orf name) psi-mi:rsmb_caeel(display_long)|uniprotkb:snr-2(gene name)|psi-mi:snr-2(display_short)|uniprotkb:W08E3.1(orf name)|uniprotkb:Sm protein B(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457960|imex:IM-11985-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00013347(gene)|ensemblmetazoa:Y59A8B.10b.1(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|refseq:NP_001256770.1|wormbase:Y59A8B.10b|interpro:IPR036612 refseq:NP_493348.1|wormbase:W08E3.1|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|reactome:R-CEL-72163|reactome:R-CEL-72165|reactome:R-CEL-111367|reactome:R-CEL-191859|reactome:R-CEL-73856|reactome:R-CEL-77588|ensemblmetazoa:W08E3.1.1(transcript)|ensemblmetazoa:WBGene00004915(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:QVaBd4MSeHKx8oQFDhK9MhOhdTA6239 rogid:AI8EhTdY6yoN4nhakXh2/TT73nY6239 intact-crc:C325451AF1E37AD4|rigid:WOCWbH7AZtR0vqH6p86RFiihpoU false sufficient binding region:49-312("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:G5EBL8 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-2003045|ensemblmetazoa:T07C4.10.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:g5ebl8_caeel(display_long)|uniprotkb:sas-7(gene name)|psi-mi:sas-7(display_short)|uniprotkb:CELE_T07C4.10(orf name)|uniprotkb:T07C4.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457936|imex:IM-11985-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) uniprotkb:Q5CZ46(uniprot-removed-ac)|refseq:NP_001022754.1|wormbase:T07C4.10|ensemblmetazoa:T07C4.10.1(transcript)|ensemblmetazoa:WBGene00011562(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:Gq35TiipmRPRgKhoiWP8t59nUK86239 intact-crc:037E8DA3D400E7E3|rigid:ffPbh7lRpjZWxCD5VRkeSCU/WYY false - sufficient binding region:495-1013("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17139 uniprotkb:Q65XX1 intact:EBI-319671|uniprotkb:Q6LAD0|ensemblmetazoa:K04H4.1a.1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:co4a1_caeel(display_long)|uniprotkb:emb-9(gene name)|psi-mi:emb-9(display_short)|uniprotkb:clb-2(gene name synonym)|uniprotkb:K04H4.1(orf name) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457946|imex:IM-11985-234 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|refseq:NP_001022663.1|wormbase:K04H4.1a|wormbase:K04H4.1b|refseq:NP_001022662.2|ensemblmetazoa:K04H4.1a.1(transcript)|ensemblmetazoa:WBGene00001263(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR036954 refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PAygwwh1z4+A+1x0KmF3LiN6qKw6239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:B85B01927781C63D|rigid:yUccmOdVsUEDOc1BvkMVH5mQjgg false sufficient binding region:494-1759("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21952 uniprotkb:Q17635 intact:EBI-326288|ensemblmetazoa:R12B2.4.1 intact:EBI-314429|uniprotkb:Q23107|ensemblmetazoa:W01B6.9.1 psi-mi:nuf2_caeel(display_long)|uniprotkb:R12B2.4(orf name)|uniprotkb:Kinetochore protein him-10(gene name synonym)|uniprotkb:Protein high incidence of males 10(gene name synonym)|uniprotkb:him-10(gene name)|psi-mi:him-10(display_short) psi-mi:ndc80_caeel(display_long)|uniprotkb:ndc-80(gene name)|psi-mi:ndc-80(display_short)|uniprotkb:W01B6.9(orf name)|uniprotkb:Hec1 homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457990|imex:IM-11985-238 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498253.1|wormbase:R12B2.4|ensemblmetazoa:R12B2.4.1(transcript)|ensemblmetazoa:WBGene00001869(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|dip:DIP-25404N refseq:NP_501830.1|wormbase:W01B6.9|ensemblmetazoa:W01B6.9.1(transcript)|ensemblmetazoa:WBGene00003576(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|go:"GO:0030334"(regulation of cell migration)|dip:DIP-25850N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:jGq4E8mXj7wTqWnEvuhDvjX2FxQ6239 rogid:VqbUclU7wKvfpUfmJTQj3SosKtg6239 intact-crc:FFEA17BAC40F7002|rigid:eQ/v7LvX6T23ARRMMktRrL9TObY false - sufficient binding region:48-201("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62332 uniprotkb:P91457 intact:EBI-317758|ensemblmetazoa:R06A4.4a.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:o62332_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:R06A4.4(orf name)|uniprotkb:CELE_R06A4.4(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457970|imex:IM-11985-236 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496987.1|wormbase:R06A4.4a|ensemblmetazoa:R06A4.4a.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|dip:DIP-25178N refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vmad0aGDqxNwqAZYykq3lZt5zUs6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:B93A1BFF44D4E4FA|rigid:BwMcVe72WExa1ANdM9/P7D9Onek false sufficient binding region:484-883("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01512 uniprotkb:Q95005 intact:EBI-316803|ensemblmetazoa:C48B6.3.1 intact:EBI-316796|ensemblmetazoa:C36B1.4.1|ensemblmetazoa:C36B1.4.2 psi-mi:o01512_caeel(display_long)|uniprotkb:C48B6.3(orf name)|uniprotkb:CELE_C48B6.3(orf name) psi-mi:psa7_caeel(display_long)|uniprotkb:pas-4(gene name)|psi-mi:pas-4(display_short)|uniprotkb:C36B1.4(orf name)|uniprotkb:Proteasome subunit alpha 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6457980|imex:IM-11985-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491971.1|wormbase:C48B6.3|ensemblmetazoa:C48B6.3.1(transcript)|ensemblmetazoa:WBGene00016741(gene)|interpro:IPR029196|interpro:IPR040308 reactome:R-CEL-5689603|reactome:R-CEL-5689880|refseq:NP_492360.1|wormbase:C36B1.4|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:C36B1.4.1(transcript)|ensemblmetazoa:C36B1.4.2(transcript)|ensemblmetazoa:WBGene00003925(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Qcn8ejgZlEib9/98VmiZlC3VLHg6239 rogid:WWXt5jeuKRCX9WomT3Wqk45PRIc6239 intact-crc:EA24AF2178C0966D|rigid:bVcY1Uabvnu9oe7sRvcwSu7F1eY false sufficient binding region:48-206("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76258 uniprotkb:Q8MQ04 intact:EBI-2002148|ensemblmetazoa:C09G12.9.1 intact:EBI-313218|ensemblmetazoa:M03D4.1c.1 psi-mi:o76258_caeel(display_long)|uniprotkb:tsg-101(gene name)|psi-mi:tsg-101(display_short)|uniprotkb:CELE_C09G12.9(orf name)|uniprotkb:C09G12.9(orf name) psi-mi:q8mq04_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:M03D4.1(orf name)|uniprotkb:CELE_M03D4.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458020|imex:IM-11985-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500364.2|wormbase:C09G12.9|interpro:IPR017916|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR008883(Tumour susceptibility gene 101)|reactome:R-CEL-917729|interpro:IPR037202|ensemblmetazoa:C09G12.9.1(transcript)|ensemblmetazoa:WBGene00015658(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process) refseq:NP_001023311.1|wormbase:M03D4.1c|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR032384|ensemblmetazoa:M03D4.1c.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR027417|interpro:IPR038105|interpro:IPR027640 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tAhzbKmVoJZA+IwR6RLdGgDFIYI6239 rogid:qAci4uz+7AlWxi0T8ZVymtdA6WU6239 intact-crc:CA2B30951B3DEEC0|rigid:U17Vo4n+xIrnep28gljoRFKrU9g false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45087 uniprotkb:Q22799 intact:EBI-313406|ensemblmetazoa:C17H12.1.1 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:o45087_caeel(display_long)|uniprotkb:dyci-1(gene name)|psi-mi:dyci-1(display_short)|uniprotkb:C17H12.1(orf name)|uniprotkb:CELE_C17H12.1(orf name) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458000|imex:IM-11985-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501038.1|ensemblmetazoa:C17H12.1.1(transcript)|ensemblmetazoa:WBGene00015927(gene)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0010970"(transport along microtubule)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-CEL-6811436|wormbase:C17H12.1a|reactome:R-CEL-9646399|dip:DIP-25870N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CpgxxRfSkDSDUCfcxsooWU8jsv06239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:ED05D8A4C267CE33|rigid:xls2Jfh6UJuAmUSCRfRA8872iVQ false sufficient binding region:48-151("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86D01 uniprotkb:P34331-2 intact:EBI-2002309|ensemblmetazoa:ZK809.5b.1 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 psi-mi:q86d01_caeel(display_long)|uniprotkb:ZK809.5(orf name)|uniprotkb:CELE_ZK809.5(orf name) psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458010|imex:IM-11985-240 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023625.1|wormbase:ZK809.5b|ensemblmetazoa:WBGene00014087(gene)|ensemblmetazoa:ZK809.5b.1(transcript) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:uLinzbAGdgl/UL8Bi1WoXYZMMcI6239 rogid:u830S0jdkV753ilx7DbxmhPocv86239 intact-crc:4989C78B63B2011A|rigid:sLAzNYCO1PjM3EGiZW1EIAU9Z8U false sufficient binding region:474-708("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19371 uniprotkb:Q17796 intact:EBI-2005696|ensemblmetazoa:F12F6.6.1 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 psi-mi:q19371_caeel(display_long)|uniprotkb:sec-24.1(gene name)|psi-mi:sec-24.1(display_short)|uniprotkb:CELE_F12F6.6(orf name)|uniprotkb:F12F6.6(orf name) psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458050|imex:IM-11985-244 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502178.1|wormbase:F12F6.6|interpro:IPR007123(Gelsolin region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|reactome:R-CEL-204005|reactome:R-CEL-5694530|reactome:R-CEL-983170|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|ensemblmetazoa:F12F6.6.1(transcript)|ensemblmetazoa:WBGene00004755(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:dg1hd9LmcymwnqpcxF0TbE37fZA6239 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 intact-crc:7FA38CBBDA79585E|rigid:Bwy4ClJOrLbU+LKIMJI2MOcM9hY false - sufficient binding region:467-729("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34331-2 uniprotkb:Q21776 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 intact:EBI-331300|ensemblmetazoa:R06C7.8.1 psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:bub1_caeel(display_long)|uniprotkb:bub-1(gene name)|psi-mi:bub-1(display_short)|uniprotkb:Budding uninhibited by benzimidazole 1(gene name synonym)|uniprotkb:R06C7.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458030|imex:IM-11985-242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) refseq:NP_492051.1|wormbase:R06C7.8|dip:DIP-27465N|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensemblmetazoa:R06C7.8.1(transcript)|ensemblmetazoa:WBGene00000275(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000280"(nuclear division)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008406"(gonad development)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0051316"(attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR000719(Protein kinase, core)|reactome:R-CEL-141430 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:u830S0jdkV753ilx7DbxmhPocv86239 rogid:vCA2zo1b4B9goXwPJfQDrOZhHjY6239 intact-crc:CA783DDD57E52933|rigid:SiWBrX35BIKaJ6fma3pmkKeHkmw false - sufficient binding region:470-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:Q94361-2 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-1459355|ensemblmetazoa:W10D5.3f.1|ensemblmetazoa:W10D5.3f.2|ensemblmetazoa:W10D5.3f.3|ensemblmetazoa:W10D5.3f.4 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:q94361-2(display_long)|uniprotkb:E3 SUMO-protein transferase gei-17(gene name synonym)|uniprotkb:f(isoform synonym)|uniprotkb:gei-17(gene name)|psi-mi:gei-17(display_short)|uniprotkb:Gex-3-interacting protein 17(gene name synonym)|uniprotkb:W10D5.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458040|imex:IM-11985-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 intact:EBI-323258(isoform-parent)|ensemblmetazoa:W10D5.3f.1(transcript)|ensemblmetazoa:W10D5.3f.2(transcript)|ensemblmetazoa:W10D5.3f.3(transcript)|ensemblmetazoa:W10D5.3f.4(transcript)|ensemblmetazoa:WBGene00001574(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:aex9HUd1bSXGSobKUMDhc+0FZTQ6239 intact-crc:B161EA1E746F0955|rigid:lPCca09RsgfncX6OaTJyz+E0dCQ false - sufficient binding region:455-753("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01501-1 uniprotkb:O01541 intact:EBI-6457824|ensemblmetazoa:C37A2.4a.1 intact:EBI-2002688|uniprotkb:Q17371|ensemblmetazoa:F28H1.3.1|ensemblmetazoa:F28H1.3.2|ensemblmetazoa:F28H1.3.3|ensemblmetazoa:F28H1.3.4 psi-mi:o01501-1(display_long)|uniprotkb:C37A2.4(orf name)|uniprotkb:cye-1(gene name)|psi-mi:cye-1(display_short) psi-mi:syac_caeel(display_long)|uniprotkb:ars-2(gene name synonym)|uniprotkb:AlaRS A(gene name synonym)|uniprotkb:aars-2(gene name)|psi-mi:aars-2(display_short)|uniprotkb:F28H1.3(orf name)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458080|imex:IM-11985-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C37A2.4a.1(transcript)|ensemblmetazoa:WBGene00000871(gene)|intact:EBI-6499833(isoform-parent) interpro:IPR018162|interpro:IPR018165|interpro:IPR018164|interpro:IPR023033|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR018163|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|refseq:NP_491281.1|wormbase:F28H1.3|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|ensemblmetazoa:F28H1.3.1(transcript)|ensemblmetazoa:F28H1.3.2(transcript)|ensemblmetazoa:F28H1.3.3(transcript)|ensemblmetazoa:F28H1.3.4(transcript)|ensemblmetazoa:WBGene00000197(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:THl5Hcv1lfLuT3xEXRZhEQm1+886239 rogid:t0FAfpVq+yvdlPawKsc0Iuhyn8Q6239 intact-crc:3D080C5433B7C1C4|rigid:G1sf2ReE5hwtBiXAKrUDFoxjOew false - sufficient binding region:464-596("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDA3 uniprotkb:Q18282 intact:EBI-1000576|ensemblmetazoa:T03F1.9.1|ensemblmetazoa:T03F1.9.2 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 psi-mi:g5eda3_caeel(display_long)|uniprotkb:hcp-4(gene name)|psi-mi:hcp-4(display_short)|uniprotkb:CELE_T03F1.9(orf name)|uniprotkb:T03F1.9(orf name) psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458060|imex:IM-11985-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T03F1.9.1(transcript)|ensemblmetazoa:T03F1.9.2(transcript)|ensemblmetazoa:WBGene00001832(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0046603"(negative regulation of mitotic centrosome separation)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070199"(establishment of protein localization to chromosome)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098813"(nuclear chromosome segregation)|uniprotkb:P91426(uniprot-removed-ac)|refseq:NP_491244.1|wormbase:T03F1.9 refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:xNd7rm0fgMYgB7DPhWZLMSdR5RA6239 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 intact-crc:81C3F354847230F2|rigid:q6Ey5L7whxgqHvyUb6AVuupHFvg false sufficient binding region:467-599("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21341 uniprotkb:Q20168 intact:EBI-1811800|ensemblmetazoa:K08E7.3.1 intact:EBI-895887|ensemblmetazoa:F38E11.5.1 psi-mi:let99_caeel(display_long)|uniprotkb:let-99(gene name)|psi-mi:let-99(display_short)|uniprotkb:Lethal protein 99(gene name synonym)|uniprotkb:K08E7.3(orf name) psi-mi:copb2_caeel(display_long)|uniprotkb:copb-2(gene name)|psi-mi:copb-2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:F38E11.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458070|imex:IM-11985-246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502407.1|wormbase:K08E7.3|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9013424|reactome:R-CEL-9035034|interpro:IPR036388|interpro:IPR036390|ensemblmetazoa:K08E7.3.1(transcript)|ensemblmetazoa:WBGene00002368(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005938"(cell cortex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051301"(cell division) refseq:NP_501671.1|wormbase:F38E11.5|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|reactome:R-CEL-6807878|reactome:R-CEL-6811434|ensemblmetazoa:F38E11.5.1(transcript)|ensemblmetazoa:WBGene00009542(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048599"(oocyte development) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:rARdgvl4l+tXuawwY+bTaTRQNBg6239 rogid:3SJ6S3Htfpx07drbV+B3WtohNNs6239 intact-crc:DFAA1C81030E48F4|rigid:YDP0usy0ZclIL+Hs1ZmVKptSJts false - sufficient binding region:465-598("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE37 uniprotkb:O01427 intact:EBI-312981|ensemblmetazoa:Y39G10AR.13a.1|ensemblmetazoa:Y39G10AR.13a.2 intact:EBI-312947|ensemblmetazoa:B0207.4.1 psi-mi:g5ee37_caeel(display_long)|uniprotkb:icp-1(gene name)|psi-mi:icp-1(display_short)|uniprotkb:Y39G10AR.13(orf name)|uniprotkb:CELE_Y39G10AR.13(orf name) psi-mi:air2_caeel(display_long)|uniprotkb:stu-7(gene name synonym)|uniprotkb:B0207.4(orf name)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym)|uniprotkb:air-2(gene name)|psi-mi:air-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458110|imex:IM-11985-250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9GSQ0(uniprot-removed-ac)|wormbase:Y39G10AR.13a|interpro:IPR039130|ensemblmetazoa:WBGene00002047(gene)|ensemblmetazoa:Y39G10AR.13a.1(transcript)|ensemblmetazoa:Y39G10AR.13a.2(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030496"(midbody)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098813"(nuclear chromosome segregation)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1990385"(meiotic spindle midzone)|interpro:IPR005635(Inner centromere protein, ARK binding region)|refseq:NP_490956.1 refseq:NP_491714.1|wormbase:B0207.4|ensemblmetazoa:B0207.4.1(transcript)|ensemblmetazoa:WBGene00000099(gene)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR030616|dip:DIP-25477N|reactome:R-CEL-8854050 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:wOoAvytoIzGSkKwLIoJM+rc5pa46239 rogid:YZlndh7GD6pSNdkb4miBUf335Sc6239 intact-crc:17002B8518E7D4D6|rigid:qX4VLERR0c2nNfCAldASS6sMyQs false sufficient binding region:451-622("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBX2 uniprotkb:Q8TA83-2 intact:EBI-316840|ensemblmetazoa:R07B7.2a.1 intact:EBI-680063|ensemblmetazoa:F22B7.5b.1 psi-mi:g5ebx2_caeel(display_long)|uniprotkb:R07B7.2(orf name)|uniprotkb:CELE_R07B7.2(orf name) psi-mi:q8ta83-2(display_long)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:F22B7.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458090|imex:IM-11985-248 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q95QM1(uniprot-removed-ac)|refseq:NP_001256397.1|wormbase:R07B7.2a|ensemblmetazoa:R07B7.2a.1(transcript)|ensemblmetazoa:WBGene00011087(gene) intact:EBI-331999(dnj10_caeel)|ensemblmetazoa:F22B7.5b.1(transcript)|ensemblmetazoa:WBGene00001028(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:GHq1/JUFM5JRxCdgOQ/xbXUQB7I6239 rogid:ZpgWCeAeWbLWXJuhUSVyjnUmraw6239 intact-crc:B6472BAE94CAB4D2|rigid:i7y44GzZWUNBXmAiuWyxPoOTrzw false sufficient binding region:45-636("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94361-4 uniprotkb:P55853 intact:EBI-1459365|ensemblmetazoa:W10D5.3e.1|ensemblmetazoa:W10D5.3e.2|ensemblmetazoa:W10D5.3e.3|ensemblmetazoa:W10D5.3e.4 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:q94361-4(display_long)|uniprotkb:E3 SUMO-protein transferase gei-17(gene name synonym)|uniprotkb:e(isoform synonym)|uniprotkb:gei-17(gene name)|psi-mi:gei-17(display_short)|uniprotkb:Gex-3-interacting protein 17(gene name synonym)|uniprotkb:W10D5.3(orf name) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458100|imex:IM-11985-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-323258(isoform-parent)|ensemblmetazoa:W10D5.3e.1(transcript)|ensemblmetazoa:W10D5.3e.2(transcript)|ensemblmetazoa:W10D5.3e.3(transcript)|ensemblmetazoa:W10D5.3e.4(transcript)|ensemblmetazoa:WBGene00001574(gene) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:9DTWFqcU+3HYxp39NMfnH70uqZs6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:F0C37A239B3C6E09|rigid:o0IcEl9d32JzKnXGbu/jv87OEtw false sufficient binding region:440-663("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEG8 uniprotkb:Q09599 intact:EBI-329812|ensemblmetazoa:ZK270.2d.1 intact:EBI-2004725|ensemblmetazoa:R06F6.1.1 psi-mi:g5eeg8_caeel(display_long)|uniprotkb:frm-1(gene name)|psi-mi:frm-1(display_short)|uniprotkb:ZK270.2(orf name)|uniprotkb:CELE_ZK270.2(orf name) psi-mi:slbp_caeel(display_long)|uniprotkb:cdl-1(gene name)|psi-mi:cdl-1(display_short)|uniprotkb:Histone stem-loop-binding protein(gene name synonym)|uniprotkb:R06F6.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458130|imex:IM-11985-252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|refseq:NP_493601.2|uniprotkb:Q9TVI9(uniprot-removed-ac)|interpro:IPR014847("FERM adjacent (FA)")|wormbase:ZK270.2d|interpro:IPR029071|reactome:R-CEL-6794361|interpro:IPR035963|ensemblmetazoa:WBGene00001488(gene)|ensemblmetazoa:ZK270.2d.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0031032"(actomyosin structure organization) wormbase:R06F6.1|interpro:IPR026502|reactome:R-CEL-77588|interpro:IPR029344|interpro:IPR038294|reactome:R-CEL-73856|refseq:NP_496320.4|ensemblmetazoa:R06F6.1.1(transcript)|ensemblmetazoa:WBGene00000411(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0006915"(apoptotic process)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0051028"(mRNA transport)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:RghSgD3sbqRSrqX0KA/QfCPaFn86239 rogid:2Y2MhtayRwOZm+MaK6fQEHIkzuw6239 intact-crc:F82978B68031A00C|rigid:NYbjQ0n1O6ncreZWxZLIwMy0PvU false sufficient binding region:4497-4648("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44761 uniprotkb:P91276 intact:EBI-2005221|ensemblmetazoa:T12F5.1.1 intact:EBI-324490|ensemblmetazoa:F26B1.3.1 psi-mi:o44761_caeel(display_long)|uniprotkb:sld-2(gene name)|psi-mi:sld-2(display_short)|uniprotkb:CELE_T12F5.1(orf name)|uniprotkb:T12F5.1(orf name) psi-mi:ima2_caeel(display_long)|uniprotkb:ima-2(gene name)|psi-mi:ima-2(display_short)|uniprotkb:F26B1.3(orf name)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458140|imex:IM-11985-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491210.1|wormbase:T12F5.1|ensemblmetazoa:T12F5.1.1(transcript)|ensemblmetazoa:WBGene00020466(gene) refseq:NP_491824.1|wormbase:F26B1.3|ensemblmetazoa:F26B1.3.1(transcript)|ensemblmetazoa:WBGene00002073(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|dip:DIP-26785N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aGo4EtKYh8jY3ceq8kjre/Kwqws6239 rogid:p8jH6WIdh8iihdRyH6tbz2yqDxQ6239 intact-crc:20DCB830D5FCC1CF|rigid:GPWPzLt+Jll6dnNZPH4BLv/mdtM false - sufficient binding region:44-531("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QC4 uniprotkb:Q04908 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 intact:EBI-312239|ensemblmetazoa:C30C11.2.1|ensemblmetazoa:C30C11.2.2 psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:psmd3_caeel(display_long)|uniprotkb:rpn-3(gene name)|psi-mi:rpn-3(display_short)|uniprotkb:C30C11.2(orf name)|uniprotkb:26S proteasome regulatory subunit rpn-3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458120|imex:IM-11985-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 ensemblmetazoa:C30C11.2.1(transcript)|ensemblmetazoa:C30C11.2.2(transcript)|ensemblmetazoa:WBGene00004460(gene)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|reactome:R-CEL-8932339|refseq:NP_498869.1|wormbase:C30C11.2|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|dip:DIP-25350N|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 rogid:BqkDfwgUOBB10iU30JSY8C123tU6239 intact-crc:BD12933A678A1C23|rigid:6LIvs0yISM4hkgRHu4Ir9Rg77vY false - sufficient binding region:451-481("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:O76258 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2002148|ensemblmetazoa:C09G12.9.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:o76258_caeel(display_long)|uniprotkb:tsg-101(gene name)|psi-mi:tsg-101(display_short)|uniprotkb:CELE_C09G12.9(orf name)|uniprotkb:C09G12.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458175|imex:IM-11985-256 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_500364.2|wormbase:C09G12.9|interpro:IPR017916|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR008883(Tumour susceptibility gene 101)|reactome:R-CEL-917729|interpro:IPR037202|ensemblmetazoa:C09G12.9.1(transcript)|ensemblmetazoa:WBGene00015658(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:tAhzbKmVoJZA+IwR6RLdGgDFIYI6239 intact-crc:C779DC529D41D036|rigid:/MRv/SLSW+yk2A4BxJder15BmWA false sufficient binding region:444-645("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23237 uniprotkb:Q9XVU8 intact:EBI-314040|ensemblmetazoa:Y38A8.2.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:psb3_caeel(display_long)|uniprotkb:pbs-3(gene name)|psi-mi:pbs-3(display_short)|uniprotkb:Y38A8.2(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458150|imex:IM-11985-254 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8932339|refseq:NP_494913.1|wormbase:Y38A8.2|reactome:R-CEL-5632684|ensemblmetazoa:WBGene00003949(gene)|ensemblmetazoa:Y38A8.2.1(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-25063N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XDQsAOH8E9LxVDloQ25KGEoFB6c6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:7EA25CB6821F0EEF|rigid:Lrova72kiVhL/1aS/+Us+Y+o3hc false - sufficient binding region:444-894("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q9XTF3-3 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-6458160|ensemblmetazoa:F49E11.1c.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q9xtf3-3(display_long)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:F49E11.1(orf name)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458165|imex:IM-11985-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 intact:EBI-2005616(isoform-parent)|ensemblmetazoa:F49E11.1c.1(transcript)|ensemblmetazoa:WBGene00003150(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:q+r0vN0DzQfPQs5H4lzQOgECK1k6239 intact-crc:B6F618505DDF4D5D|rigid:wpIeSTGuKrez5V48R4u8TnT26Ck false sufficient binding region:444-774("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:Q9XVU8 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458210|imex:IM-11985-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:C847891448D3EDB1|rigid:XS5yDD07duCJn5hd+1DGguD68Jk false - sufficient binding region:444-571("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q21295 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2004307|uniprotkb:Q21296|ensemblmetazoa:K07F5.13a.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q21295_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458185|imex:IM-11985-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_501772.1|wormbase:K07F5.13a|interpro:IPR024864|interpro:IPR025712|ensemblmetazoa:K07F5.13a.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:CgqZPl+7gsTQJxOMbCCLLuEiUh46239 intact-crc:F0BA54A077412C43|rigid:IyQ8k6NQjDTpQGPM/4KOW69Y6x4 false sufficient binding region:444-645("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EG38 uniprotkb:G4RT11 intact:EBI-311807|ensemblmetazoa:F10B5.6.1 intact:EBI-6458195|ensemblmetazoa:B0511.9c.1|uniprotkb:A9D8E6|uniprotkb:G4RT06|uniprotkb:H2KYB5 psi-mi:cdc16_caeel(display_long)|uniprotkb:emb-27(gene name)|psi-mi:emb-27(display_short)|uniprotkb:Abnormal embryogenesis protein 27(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:apc-6(gene name synonym)|uniprotkb:pod-6(gene name synonym)|uniprotkb:F10B5.6(orf name) psi-mi:cdc26_caeel(display_long)|uniprotkb:Cell division cycle protein 26 homolog(gene name synonym)|uniprotkb:mat-4(gene name synonym)|uniprotkb:tag-265(gene name synonym)|uniprotkb:B0511.9(orf name)|uniprotkb:cdc-26(gene name)|psi-mi:cdc-26(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458200|imex:IM-11985-258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q09536(uniprot-removed-ac)|ensemblmetazoa:F10B5.6.1(transcript)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|ensemblmetazoa:WBGene00001281(gene)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030703"(eggshell formation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:NP_495712.1|wormbase:F10B5.6|reactome:R-CEL-983168 ensemblmetazoa:B0511.9c.1(transcript)|ensemblmetazoa:WBGene00015235(gene)|go:"GO:0005634"(nucleus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:B0511.9a|wormbase:B0511.9b|wormbase:B0511.9d|refseq:NP_001251445.1|refseq:NP_740913.3|refseq:NP_740914.2|refseq:NP_001251447.1|wormbase:B0511.9c|dip:DIP-26086N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:m3yOdVjLNJWITbYs0dThwJzPRf86239 rogid:4EiUm/eby0CTOnoyalmBYdJZmOE6239 intact-crc:3FE917D110195CF3|rigid:ivCnfVM6NCgb+JSxo63DSKR2rAg false sufficient binding region:444-595("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TA83-2 uniprotkb:Q9U389 intact:EBI-680063|ensemblmetazoa:F22B7.5b.1 intact:EBI-312154|ensemblmetazoa:R102.5b.1|uniprotkb:Q21891 psi-mi:q8ta83-2(display_long)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:F22B7.5(orf name) psi-mi:allo1_caeel(display_long)|uniprotkb:allo-1(gene name)|psi-mi:allo-1(display_short)|uniprotkb:R102.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458220|imex:IM-11985-260 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-331999(dnj10_caeel)|ensemblmetazoa:F22B7.5b.1(transcript)|ensemblmetazoa:WBGene00001028(gene) refseq:NP_501980.2|wormbase:R102.5b|ensemblmetazoa:R102.5b.1(transcript)|ensemblmetazoa:WBGene00011292(gene)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0030017"(sarcomere)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055120"(striated muscle dense body)|dip:DIP-26223N|wormbase:R102.5a|refseq:NP_501981.2 psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZpgWCeAeWbLWXJuhUSVyjnUmraw6239 rogid:d3u/aMOFCEfGCM+om3aqhTSaf9Q6239 intact-crc:B3C0F02C51DFDFB9|rigid:0NatK12OVEsIzS4skJ8dZONg+0s false - sufficient binding region:44-402("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34685 uniprotkb:P34686 intact:EBI-2002971|ensemblmetazoa:D2024.6.1|ensemblmetazoa:D2024.6.2 intact:EBI-332095|ensemblmetazoa:M106.5.1 psi-mi:capza_caeel(display_long)|uniprotkb:cap-1(gene name)|psi-mi:cap-1(display_short)|uniprotkb:D2024.6(orf name) psi-mi:capzb_caeel(display_long)|uniprotkb:cap-2(gene name)|psi-mi:cap-2(display_short)|uniprotkb:M106.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458230|imex:IM-11985-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501145.1|wormbase:D2024.6|interpro:IPR017865|interpro:IPR002189(F-actin capping protein, alpha subunit)|reactome:R-CEL-983231|reactome:R-CEL-6807878|reactome:R-CEL-6811436|interpro:IPR042276|interpro:IPR037282|reactome:R-CEL-3371497|interpro:IPR042489|ensemblmetazoa:D2024.6.1(transcript)|ensemblmetazoa:D2024.6.2(transcript)|ensemblmetazoa:WBGene00000292(gene)|go:"GO:0005869"(dynactin complex)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping) reactome:R-CEL-983231|refseq:NP_496336.1|wormbase:M106.5|dip:DIP-26957N|reactome:R-CEL-6807878|reactome:R-CEL-6811436|ensemblmetazoa:M106.5.1(transcript)|ensemblmetazoa:WBGene00000293(gene)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005869"(dynactin complex)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|reactome:R-CEL-3371497|reactome:R-CEL-9013405|reactome:R-CEL-9035034 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:urC1b2UVDhFAvuluH5tTQnF6WjY6239 rogid:Cf9jJYjl454AP1EP38emiQ++rTA6239 intact-crc:AB6BFE390FF8433B|rigid:0mgh5ts2c0UYN3zm+DFiszTM/Xg false - sufficient binding region:44-270("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34540 uniprotkb:O44781 intact:EBI-315657|ensemblmetazoa:R05D3.7.1 intact:EBI-331944|ensemblmetazoa:F33D11.10.1 psi-mi:kinh_caeel(display_long)|uniprotkb:unc-116(gene name)|psi-mi:unc-116(display_short)|uniprotkb:R05D3.7(orf name)|uniprotkb:Uncoordinated protein 116(gene name synonym)|uniprotkb:khc-1(gene name synonym) psi-mi:o44781_caeel(display_long)|uniprotkb:F33D11.10(orf name)|uniprotkb:CELE_F33D11.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458260|imex:IM-11985-264 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498842.1|wormbase:R05D3.7|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|ensemblmetazoa:R05D3.7.1(transcript)|ensemblmetazoa:WBGene00006840(gene)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016938"(kinesin I complex)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0040011"(locomotion)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051296"(establishment of meiotic spindle orientation)|go:"GO:0098957"(anterograde axonal transport of mitochondrion)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR036961|reactome:R-CEL-983189 refseq:NP_491703.1|wormbase:F33D11.10|dip:DIP-27243N|ensemblmetazoa:F33D11.10.1(transcript)|ensemblmetazoa:WBGene00018007(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071048"|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0016787"(hydrolase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:O8CqRBiCNZOLtMJb7Y0TtQC9ZeM6239 rogid:yl7i4pfqQXlZ+Z90Bssucpen6UQ6239 intact-crc:F3278F3DA0E6A06D|rigid:RsdmWv3kuKIHVwJg6En+v+huZH0 false sufficient binding region:433-815("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8ITV6 uniprotkb:Q09601-1 intact:EBI-319717|ensemblmetazoa:Y44E3A.6b.1|ensemblmetazoa:Y44E3A.6b.2 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:q8itv6_caeel(display_long)|uniprotkb:edc-4(gene name)|psi-mi:edc-4(display_short)|uniprotkb:CELE_Y44E3A.6(orf name)|uniprotkb:Y44E3A.6(orf name) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458240|imex:IM-11985-262 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740828.1|wormbase:Y44E3A.6b|interpro:IPR000253(Forkhead-associated)|ensemblmetazoa:WBGene00021551(gene)|ensemblmetazoa:Y44E3A.6b.1(transcript)|ensemblmetazoa:Y44E3A.6b.2(transcript)|go:"GO:0000932"(P-body)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|reactome:R-CEL-430039|interpro:IPR032401 intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:AmO3iQKS9B88Xq2SgMlDJE4JCfs6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:D19EC16ED616A0A1|rigid:u2bz/3/9ZEzkYGGTq8ChZMbo4B4 false sufficient binding region:436-843("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95X44 uniprotkb:O62305 intact:EBI-320484|ensemblmetazoa:C17H12.14.1 intact:EBI-313095|uniprotkb:A5JYT0|uniprotkb:A7LPH2|uniprotkb:B3GWC8|uniprotkb:O62304|uniprotkb:Q21431|uniprotkb:Q7JLT8|uniprotkb:Q9NG91|uniprotkb:Q9NH55|uniprotkb:Q9NH56|uniprotkb:Q9NH57|uniprotkb:Q9NH58|uniprotkb:Q9NH59|uniprotkb:Q9NH60|uniprotkb:Q9U6Q0 psi-mi:q95x44_caeel(display_long)|uniprotkb:vha-8(gene name)|psi-mi:vha-8(display_short)|uniprotkb:CELE_C17H12.14(orf name)|uniprotkb:C17H12.14(orf name) psi-mi:kcc2d_caeel(display_long)|uniprotkb:unc-43(gene name)|psi-mi:unc-43(display_short)|uniprotkb:Uncoordinated protein 43(gene name synonym)|uniprotkb:K11E8.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458250|imex:IM-11985-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501040.1|wormbase:C17H12.14|ensemblmetazoa:C17H12.14.1(transcript)|ensemblmetazoa:WBGene00006917(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|interpro:IPR038495|reactome:R-CEL-1222556|reactome:R-CEL-77387|dip:DIP-24784N|reactome:R-CEL-917977|reactome:R-CEL-983712|reactome:R-CEL-9639288 refseq:NP_001023293.2|refseq:NP_001023294.1|refseq:NP_001023296.1|refseq:NP_001023297.1|refseq:NP_001023298.1|refseq:NP_001023299.1|refseq:NP_001023300.1|refseq:NP_001023301.1|refseq:NP_001023302.1|refseq:NP_001023303.1|refseq:NP_001023304.1|refseq:NP_001122788.1|refseq:NP_001122789.1|refseq:NP_001129863.1|wormbase:K11E8.1a|wormbase:K11E8.1b|wormbase:K11E8.1d|wormbase:K11E8.1e|wormbase:K11E8.1f|wormbase:K11E8.1g|wormbase:K11E8.1h|wormbase:K11E8.1i|wormbase:K11E8.1k|wormbase:K11E8.1l|wormbase:K11E8.1m|wormbase:K11E8.1n|wormbase:K11E8.1o|wormbase:K11E8.1p|go:"GO:0000165"(MAPK cascade)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042427"(serotonin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072375"(medium-term memory)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2BDW|rcsb pdb:2F86|rcsb pdb:3KK8|rcsb pdb:3KK9|rcsb pdb:3KL8|dip:DIP-25971N|dip:DIP-58986N|reactome:R-CEL-3371571|reactome:R-CEL-4086398|reactome:R-CEL-438066|reactome:R-CEL-5578775|reactome:R-CEL-936837 psi-mi:"MI:0469"(intact) - caution:This sequence has been withdrawn from Uniprot.|crc64:3231366FFF81A695 figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mBB4i2zR6qIyGppEueZ3Gi9v+2w6239 rogid:C4NFZBXWJlS7vjsWwkCSwnf76zM6239 intact-crc:8B55656B10D67ED5|rigid:S9zarQy1QSXKaRiVxgsa6iP84kk false - sufficient binding region:435-720("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34808-1 uniprotkb:P34808 intact:EBI-6458290|ensemblmetazoa:T01G9.5a.1 intact:EBI-323248|intact:EBI-521368|uniprotkb:Q8I4G6|ensemblmetazoa:T01G9.5a.1 psi-mi:p34808-1(display_long)|uniprotkb:Katanin p60 ATPase-containing subunit A1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:T01G9.5(orf name)|uniprotkb:mei-1(gene name)|psi-mi:mei-1(display_short) psi-mi:ktna1_caeel(display_long)|uniprotkb:mei-1(gene name)|psi-mi:mei-1(display_short)|uniprotkb:Katanin p60 ATPase-containing subunit A1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:T01G9.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458295|imex:IM-11985-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T01G9.5a.1(transcript)|ensemblmetazoa:WBGene00003183(gene)|intact:EBI-323248(isoform-parent) refseq:NP_492257.1|refseq:NP_871793.1|wormbase:T01G9.5a|wormbase:T01G9.5b|ensemblmetazoa:T01G9.5a.1(transcript)|ensemblmetazoa:WBGene00003183(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000785"(chromatin)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051013"(microtubule severing)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0005813"(centrosome)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0090736"(MATH domain binding)|go:"GO:1902120"(negative regulation of meiotic spindle elongation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR028596|interpro:IPR041569|rcsb pdb:5WC0|rcsb pdb:5WC1|rcsb pdb:5WCB|rcsb pdb:6B5D|go:"GO:0005819"(spindle)|rcsb pdb:6UGD|rcsb pdb:6UGE|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|rcsb pdb:6UGF|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008017"(microtubule binding)|go:"GO:0008352"(katanin complex)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|dip:DIP-25343N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W8dzUByepgfcMfSsWiLQdK+/pus6239 rogid:W8dzUByepgfcMfSsWiLQdK+/pus6239 intact-crc:0DEA207CC7504788|rigid:wlgQ4B7KwlJrkdPEh625PoLr4eI false - sufficient binding region:42-472("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5U1 uniprotkb:Q9NES7 intact:EBI-2005375|ensemblmetazoa:T22F3.3a.1 intact:EBI-312701|ensemblmetazoa:Y39B6A.1.1 psi-mi:q9n5u1_caeel(display_long)|uniprotkb:pygl-1(gene name)|psi-mi:pygl-1(display_short)|uniprotkb:CELE_T22F3.3(orf name)|uniprotkb:T22F3.3(orf name) psi-mi:q9nes7_caeel(display_long)|uniprotkb:Y39B6A.1(orf name)|uniprotkb:CELE_Y39B6A.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458270|imex:IM-11985-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504007.1|wormbase:T22F3.3a|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|reactome:R-CEL-70221|interpro:IPR035090|ensemblmetazoa:T22F3.3a.1(transcript)|ensemblmetazoa:WBGene00020696(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity) refseq:NP_741698.1|wormbase:Y39B6A.1|ensemblmetazoa:WBGene00012664(gene)|ensemblmetazoa:Y39B6A.1.1(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|dip:DIP-25463N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hxlfa3e+4GTuwc4kabxrVxbDecs6239 rogid:6zMeRngB/ofLajp54qhQGJW0o+86239 intact-crc:921F6061FEBE890A|rigid:SIBb84x9YB/r6+8Ndwr/rY6teKQ false - sufficient binding region:428-735("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18194 uniprotkb:Q9NES7 intact:EBI-2002421|ensemblmetazoa:C26B2.1.1 intact:EBI-312701|ensemblmetazoa:Y39B6A.1.1 psi-mi:q18194_caeel(display_long)|uniprotkb:dnc-4(gene name)|psi-mi:dnc-4(display_short)|uniprotkb:CELE_C26B2.1(orf name)|uniprotkb:C26B2.1(orf name) psi-mi:q9nes7_caeel(display_long)|uniprotkb:Y39B6A.1(orf name)|uniprotkb:CELE_Y39B6A.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458280|imex:IM-11985-266 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501344.1|wormbase:C26B2.1|interpro:IPR008603(Dynactin p62)|reactome:R-CEL-6811436|reactome:R-CEL-3371497|reactome:R-CEL-6807878|ensemblmetazoa:C26B2.1.1(transcript)|ensemblmetazoa:WBGene00016124(gene)|go:"GO:0005869"(dynactin complex) refseq:NP_741698.1|wormbase:Y39B6A.1|ensemblmetazoa:WBGene00012664(gene)|ensemblmetazoa:Y39B6A.1.1(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|dip:DIP-25463N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XgXybdcDeIC6UEGYvvS5eSemoiE6239 rogid:6zMeRngB/ofLajp54qhQGJW0o+86239 intact-crc:2725541CDE6BFA1B|rigid:/tuocJiiIObYubi2ethwA/Lu/AM false - sufficient binding region:427-735("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBL8 uniprotkb:P91870 intact:EBI-2003045|ensemblmetazoa:T07C4.10.1 intact:EBI-320962|ensemblmetazoa:F32H2.3.1|ensemblmetazoa:F32H2.3.2 psi-mi:g5ebl8_caeel(display_long)|uniprotkb:sas-7(gene name)|psi-mi:sas-7(display_short)|uniprotkb:CELE_T07C4.10(orf name)|uniprotkb:T07C4.10(orf name) psi-mi:spd2_caeel(display_long)|uniprotkb:F32H2.3(orf name)|uniprotkb:spd-2(gene name)|psi-mi:spd-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458305|imex:IM-11985-268 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5CZ46(uniprot-removed-ac)|refseq:NP_001022754.1|wormbase:T07C4.10|ensemblmetazoa:T07C4.10.1(transcript)|ensemblmetazoa:WBGene00011562(gene) refseq:NP_492414.1|wormbase:F32H2.3|ensemblmetazoa:F32H2.3.1(transcript)|ensemblmetazoa:F32H2.3.2(transcript)|ensemblmetazoa:WBGene00004953(gene)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019901"(protein kinase binding)|go:"GO:0040025"(vulval development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR039103|dip:DIP-25500N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Gq35TiipmRPRgKhoiWP8t59nUK86239 rogid:GBGtZRHVbrFLFhWQy/m9+L17Etk6239 intact-crc:8B19CCBD38384A5F|rigid:aZKHYKWOGOBBJQvMM4dZXuvvkRU false sufficient binding region:424-1013("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBL8 uniprotkb:P91457 intact:EBI-2003045|ensemblmetazoa:T07C4.10.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:g5ebl8_caeel(display_long)|uniprotkb:sas-7(gene name)|psi-mi:sas-7(display_short)|uniprotkb:CELE_T07C4.10(orf name)|uniprotkb:T07C4.10(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458315|imex:IM-11985-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5CZ46(uniprot-removed-ac)|refseq:NP_001022754.1|wormbase:T07C4.10|ensemblmetazoa:T07C4.10.1(transcript)|ensemblmetazoa:WBGene00011562(gene) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Gq35TiipmRPRgKhoiWP8t59nUK86239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:3586516FB7F65854|rigid:VARxI1r0vfEDS9ItogRWqhFW+rU false sufficient binding region:424-1013("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61955-1 uniprotkb:G5EDU4 intact:EBI-6456691|ensemblmetazoa:B0348.6b.1|ensemblmetazoa:B0348.6b.2 intact:EBI-322274|ensemblmetazoa:R11E3.6a.1 psi-mi:o61955-1(display_long)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:B0348.6(orf name)|uniprotkb:ife-3(gene name)|psi-mi:ife-3(display_short) psi-mi:g5edu4_caeel(display_long)|uniprotkb:eor-1(gene name)|psi-mi:eor-1(display_short)|uniprotkb:CELE_R11E3.6(orf name)|uniprotkb:R11E3.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458345|imex:IM-11985-272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-330119(isoform-parent)|ensemblmetazoa:B0348.6b.1(transcript)|ensemblmetazoa:B0348.6b.2(transcript)|ensemblmetazoa:WBGene00002061(gene) uniprotkb:Q9TYX3(uniprot-removed-ac)|wormbase:R11E3.6a|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0051402"(neuron apoptotic process)|ensemblmetazoa:R11E3.6a.1(transcript)|ensemblmetazoa:WBGene00001324(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0001764"(neuron migration)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0040011"(locomotion)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_500645.1|interpro:IPR036236 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:444BHWm5Eiqg+MUqKRgLhbVaxUo6239 rogid:4fbu9MLnmcZfILL8uzg37Rl5vnk6239 intact-crc:F86E2BD159520390|rigid:kdLpNYBEMkWU1DkQAbv8RIYQI4A false - sufficient binding region:415-909("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22799 uniprotkb:G5EBL8 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 intact:EBI-2003045|ensemblmetazoa:T07C4.10.1 psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:g5ebl8_caeel(display_long)|uniprotkb:sas-7(gene name)|psi-mi:sas-7(display_short)|uniprotkb:CELE_T07C4.10(orf name)|uniprotkb:T07C4.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458325|imex:IM-11985-270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 uniprotkb:Q5CZ46(uniprot-removed-ac)|refseq:NP_001022754.1|wormbase:T07C4.10|ensemblmetazoa:T07C4.10.1(transcript)|ensemblmetazoa:WBGene00011562(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 rogid:Gq35TiipmRPRgKhoiWP8t59nUK86239 intact-crc:8ACCA007BC9BE001|rigid:7jer91/sh3H2r9pcl/ZWrBkl/cs false - sufficient binding region:424-1013("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09599 uniprotkb:G5EEG8 intact:EBI-2004725|ensemblmetazoa:R06F6.1.1 intact:EBI-329812|ensemblmetazoa:ZK270.2d.1 psi-mi:slbp_caeel(display_long)|uniprotkb:cdl-1(gene name)|psi-mi:cdl-1(display_short)|uniprotkb:Histone stem-loop-binding protein(gene name synonym)|uniprotkb:R06F6.1(orf name) psi-mi:g5eeg8_caeel(display_long)|uniprotkb:frm-1(gene name)|psi-mi:frm-1(display_short)|uniprotkb:ZK270.2(orf name)|uniprotkb:CELE_ZK270.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458335|imex:IM-11985-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:R06F6.1|interpro:IPR026502|reactome:R-CEL-77588|interpro:IPR029344|interpro:IPR038294|reactome:R-CEL-73856|refseq:NP_496320.4|ensemblmetazoa:R06F6.1.1(transcript)|ensemblmetazoa:WBGene00000411(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0006915"(apoptotic process)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0051028"(mRNA transport)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding) interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|refseq:NP_493601.2|uniprotkb:Q9TVI9(uniprot-removed-ac)|interpro:IPR014847("FERM adjacent (FA)")|wormbase:ZK270.2d|interpro:IPR029071|reactome:R-CEL-6794361|interpro:IPR035963|ensemblmetazoa:WBGene00001488(gene)|ensemblmetazoa:ZK270.2d.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0031032"(actomyosin structure organization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:2Y2MhtayRwOZm+MaK6fQEHIkzuw6239 rogid:RghSgD3sbqRSrqX0KA/QfCPaFn86239 intact-crc:2AF6F8B10F58A00E|rigid:NYbjQ0n1O6ncreZWxZLIwMy0PvU false - sufficient binding region:4223-4648("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:G5ECB9 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-300536|ensemblmetazoa:W03C9.7a.1|ensemblmetazoa:W03C9.7a.2|ensemblmetazoa:W03C9.7a.3|ensemblmetazoa:W03C9.7a.4 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:g5ecb9_caeel(display_long)|uniprotkb:mex-1(gene name)|psi-mi:mex-1(display_short)|uniprotkb:W03C9.7(orf name)|uniprotkb:CELE_W03C9.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458375|imex:IM-11985-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) uniprotkb:Q9XTB3(uniprot-removed-ac)|ensemblmetazoa:W03C9.7a.1(transcript)|ensemblmetazoa:W03C9.7a.2(transcript)|ensemblmetazoa:W03C9.7a.3(transcript)|ensemblmetazoa:W03C9.7a.4(transcript)|ensemblmetazoa:WBGene00003228(gene)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001708"(cell fate specification)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|wormbase:W03C9.7a|reactome:R-CEL-450385|interpro:IPR000571(Zinc finger, CCCH-type)|refseq:NP_001254325.1|interpro:IPR036855 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:XAmsta4QDpGql4LbxtPSjYQlNeY6239 intact-crc:346391F91F4E1D2B|rigid:+okpkK0zveYbE+DFcIkBXZII+Gc false - sufficient binding region:41-494("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22560 uniprotkb:P54811 intact:EBI-2002088|uniprotkb:O44926|ensemblmetazoa:T19B10.7.1|ensemblmetazoa:T19B10.7.2 intact:EBI-320245|ensemblmetazoa:C06A1.1.1 psi-mi:ima1_caeel(display_long)|uniprotkb:ima-1(gene name)|psi-mi:ima-1(display_short)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:T19B10.7(orf name) psi-mi:tera1_caeel(display_long)|uniprotkb:C06A1.1(orf name)|uniprotkb:Cell division cycle-related protein 48.1(gene name synonym)|uniprotkb:p97/CDC48 homolog 1(gene name synonym)|uniprotkb:cdc-48.1(gene name)|psi-mi:cdc-48.1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458355|imex:IM-11985-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505854.1|wormbase:T19B10.7|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR032413|reactome:R-CEL-909733|ensemblmetazoa:T19B10.7.1(transcript)|ensemblmetazoa:T19B10.7.2(transcript)|ensemblmetazoa:WBGene00002072(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity) refseq:NP_496273.1|wormbase:C06A1.1|ensemblmetazoa:C06A1.1.1(transcript)|ensemblmetazoa:WBGene00007352(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|dip:DIP-26650N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:8me8vMoriaCWdhK+Iy5x7AHOOAs6239 rogid:VgGB6CuL6hJaCop1MLkdaQAjhCE6239 intact-crc:E800F2933380366E|rigid:NpJQmai5sXlhBDP55ucxlhAVBr4 false sufficient binding region:41-524("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:G5ECB9 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-300536|ensemblmetazoa:W03C9.7a.1|ensemblmetazoa:W03C9.7a.2|ensemblmetazoa:W03C9.7a.3|ensemblmetazoa:W03C9.7a.4 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:g5ecb9_caeel(display_long)|uniprotkb:mex-1(gene name)|psi-mi:mex-1(display_short)|uniprotkb:W03C9.7(orf name)|uniprotkb:CELE_W03C9.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458365|imex:IM-11985-274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 uniprotkb:Q9XTB3(uniprot-removed-ac)|ensemblmetazoa:W03C9.7a.1(transcript)|ensemblmetazoa:W03C9.7a.2(transcript)|ensemblmetazoa:W03C9.7a.3(transcript)|ensemblmetazoa:W03C9.7a.4(transcript)|ensemblmetazoa:WBGene00003228(gene)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001708"(cell fate specification)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|wormbase:W03C9.7a|reactome:R-CEL-450385|interpro:IPR000571(Zinc finger, CCCH-type)|refseq:NP_001254325.1|interpro:IPR036855 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:XAmsta4QDpGql4LbxtPSjYQlNeY6239 intact-crc:982A76E1979013FF|rigid:lqyHHS4qZqdkd39VDLvJ9j/LmBk false - sufficient binding region:41-494("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34647-1 uniprotkb:O77469-2 intact:EBI-6455889|ensemblmetazoa:ZK632.1a.1 intact:EBI-321071|ensemblmetazoa:F56H11.1a.1 psi-mi:p34647-1(display_long)|uniprotkb:ZK632.1(orf name)|uniprotkb:mcm-6(gene name)|psi-mi:mcm-6(display_short) psi-mi:o77469-2(display_long)|uniprotkb:C(isoform synonym)|uniprotkb:fbl-1(gene name)|psi-mi:fbl-1(display_short)|uniprotkb:fbln1(gene name synonym)|uniprotkb:F56H11.1(orf name)|uniprotkb:Fibulin-1C(isoform synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458385|imex:IM-11985-276 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2006759(isoform-parent)|ensemblmetazoa:WBGene00003158(gene)|ensemblmetazoa:ZK632.1a.1(transcript) intact:EBI-321052(fbln1_caeel)|ensemblmetazoa:F56H11.1a.1(transcript)|ensemblmetazoa:WBGene00001403(gene) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Bv0Zazm8QYFQ5nW05WKMSnLzHVs6239 rogid:07Am1b+2gKUbgJSdoVZvFWqnYrs6239 intact-crc:F13F4E244A0F39BA|rigid:3NV2Gm1y4Oh5YnFK+8oXBMEc79k false - sufficient binding region:414-712("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFV3 uniprotkb:O02217 intact:EBI-1187461|intact:EBI-1187509|uniprotkb:G5EDA1|ensemblmetazoa:Y48A6B.11b.1 intact:EBI-1187455|uniprotkb:A5Z2U4|ensemblmetazoa:C25A1.9a.1 psi-mi:rsa2_caeel(display_long)|uniprotkb:Y48A6B.11(orf name)|uniprotkb:rsa-2(gene name)|psi-mi:rsa-2(display_short) psi-mi:p2r31_caeel(display_long)|uniprotkb:rsa-1(gene name)|psi-mi:rsa-1(display_short)|uniprotkb:Regulator of spindle assembly protein 1(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A 72kDa regulatory subunit rsa-1(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'' rsa-1(gene name synonym)|uniprotkb:C25A1.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458395|imex:IM-11985-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7YSJ2(uniprot-removed-ac)|refseq:NP_001022887.1|wormbase:Y48A6B.11b|wormbase:Y48A6B.11a|refseq:NP_001022886.1|ensemblmetazoa:WBGene00012972(gene)|ensemblmetazoa:Y48A6B.11b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0048566"(embryonic digestive tract development) refseq:NP_492683.1|wormbase:C25A1.9a|interpro:IPR011992(EF-Hand type)|refseq:NP_001122424.1|wormbase:C25A1.9b|ensemblmetazoa:C25A1.9a.1(transcript)|ensemblmetazoa:WBGene00007710(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR028846 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7PBwPJFROCL8Mv1INcviVzZGFCE6239 rogid:TzkShn9bEdl1tOgz8nIXnAHZar86239 intact-crc:AFB77FBCBA054CA6|rigid:9iU+XiktTbKtmYSe5X58tffejW0 false sufficient binding region:40-949("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:Q9XTF3-3 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-6458160|ensemblmetazoa:F49E11.1c.1 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:q9xtf3-3(display_long)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:F49E11.1(orf name)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458425|imex:IM-11985-280 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) intact:EBI-2005616(isoform-parent)|ensemblmetazoa:F49E11.1c.1(transcript)|ensemblmetazoa:WBGene00003150(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:q+r0vN0DzQfPQs5H4lzQOgECK1k6239 intact-crc:F9420E8838E512ED|rigid:pBWpF37Gvz31LsSyDs3MntXtuE4 false sufficient binding region:403-671("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91349 uniprotkb:G5EFV3 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 intact:EBI-1187461|intact:EBI-1187509|uniprotkb:G5EDA1|ensemblmetazoa:Y48A6B.11b.1 psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:rsa2_caeel(display_long)|uniprotkb:Y48A6B.11(orf name)|uniprotkb:rsa-2(gene name)|psi-mi:rsa-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458405|imex:IM-11985-278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N uniprotkb:Q7YSJ2(uniprot-removed-ac)|refseq:NP_001022887.1|wormbase:Y48A6B.11b|wormbase:Y48A6B.11a|refseq:NP_001022886.1|ensemblmetazoa:WBGene00012972(gene)|ensemblmetazoa:Y48A6B.11b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0048566"(embryonic digestive tract development) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2016/09/27 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rogid:7PBwPJFROCL8Mv1INcviVzZGFCE6239 intact-crc:4C7187A4D0FD6BD3|rigid:mnDJRH/ys3V7eXBvum5wE50tG0k false sufficient binding region:406-470("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45950 uniprotkb:G5ECL3 intact:EBI-2007505|ensemblmetazoa:Y48E1B.7.1 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 psi-mi:o45950_caeel(display_long)|uniprotkb:Y48E1B.7(orf name)|uniprotkb:lin-38(gene name)|psi-mi:lin-38(display_short)|uniprotkb:CELE_Y48E1B.7(orf name) psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458415|imex:IM-11985-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496852.3|wormbase:Y48E1B.7|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:WBGene00013006(gene)|ensemblmetazoa:Y48E1B.7.1(transcript)|go:"GO:0040027"(negative regulation of vulval development) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:52wNg7ZYV6jZV1YON0rZnJQwsII6239 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 intact-crc:AA58C695822171BE|rigid:Ae2vnlsNs8ejJLPH+tcwZ/tf0Q8 false sufficient binding region:403-700("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91349 uniprotkb:O01902 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 intact:EBI-317316|ensemblmetazoa:F59E12.11.1 psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:o01902_caeel(display_long)|uniprotkb:sam-4(gene name)|psi-mi:sam-4(display_short)|uniprotkb:CELE_F59E12.11(orf name)|uniprotkb:F59E12.11(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458455|imex:IM-11985-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N refseq:NP_495102.1|ensemblmetazoa:F59E12.11.1(transcript)|ensemblmetazoa:WBGene00019126(gene)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903746"(positive regulation of pharyngeal pumping)|interpro:IPR018780|go:"GO:0099078"(BORC complex)|wormbase:F59E12.11|dip:DIP-26735N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rogid:CYh19fO/xuev1wnk3G7FjIjp+Dg6239 intact-crc:EDB5855317C863BA|rigid:aWzLoJfLMN9EDflCwT+NFvUSh0A false sufficient binding region:403-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N359 uniprotkb:P34643 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 intact:EBI-324902|uniprotkb:M1ZK05|ensemblmetazoa:ZK512.5a.1 psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:sc161_caeel(display_long)|uniprotkb:sec-16A.1(gene name)|psi-mi:sec-16A.1(display_short)|uniprotkb:Secretory cargo traffic protein sec-16A.1(gene name synonym)|uniprotkb:sec-16(gene name synonym)|uniprotkb:ZK512.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458435|imex:IM-11985-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 refseq:NP_499022.1|wormbase:ZK512.5a|wormbase:ZK512.5b|ensemblmetazoa:WBGene00013985(gene)|ensemblmetazoa:ZK512.5a.1(transcript)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|refseq:NP_001293651.1|dip:DIP-25929N|reactome:R-CEL-204005 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 rogid:MNubI0LLX2Ewt6rjY5w88MQajIo6239 intact-crc:4F52ADD0CD14377A|rigid:YwczQFlbigkrQKPQsaJcuTfdqqE false - sufficient binding region:403-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:Q9N5V3 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-320898|ensemblmetazoa:C53D5.6.1 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:q9n5v3_caeel(display_long)|uniprotkb:imb-3(gene name)|psi-mi:imb-3(display_short)|uniprotkb:CELE_C53D5.6(orf name)|uniprotkb:C53D5.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458445|imex:IM-11985-282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_490715.1|wormbase:C53D5.6|ensemblmetazoa:C53D5.6.1(transcript)|ensemblmetazoa:WBGene00002077(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|interpro:IPR041389|interpro:IPR041653|dip:DIP-26917N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:+DZB8n7UfeEeXcLYSkOaYJ0YUNI6239 intact-crc:D3C6A5AD75E4368A|rigid:qS4XrrOea3t9y35XFxtw21gbz1Q false sufficient binding region:403-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:O17915 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-324099|ensemblmetazoa:K01G5.4.1 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:ran_caeel(display_long)|uniprotkb:ran-1(gene name)|psi-mi:ran-1(display_short)|uniprotkb:K01G5.4(orf name)|uniprotkb:Ras-related nuclear protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458465|imex:IM-11985-284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_499369.1|wormbase:K01G5.4|ensemblmetazoa:K01G5.4.1(transcript)|ensemblmetazoa:WBGene00004302(gene)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CEL-1655829|dip:DIP-25217N|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:yo75CoWqaTF5xYXAujyoTXXvRw86239 intact-crc:957C94F0E8376AB9|rigid:pgwmh5AogclSJTynR5EYnoXxB90 false sufficient binding region:403-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:Q21735 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-2004567|ensemblmetazoa:R05D11.3.1 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:ntf2_caeel(display_long)|uniprotkb:ran-4(gene name)|psi-mi:ran-4(display_short)|uniprotkb:R05D11.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458475|imex:IM-11985-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_492322.1|wormbase:R05D11.3|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|ensemblmetazoa:R05D11.3.1(transcript)|ensemblmetazoa:WBGene00004305(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0044613"(nuclear pore central transport channel) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:MO3nF45y4Qnv1bnk707RFa3N6hU6239 intact-crc:31911727A84BB963|rigid:OirxF0LosKJvusKKT7GAj9G7gsU false sufficient binding region:403-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22747 uniprotkb:Q9U2Z1 intact:EBI-324189|ensemblmetazoa:T24F1.2.1 intact:EBI-2006699|ensemblmetazoa:Y113G7A.3.1 psi-mi:tm201_caeel(display_long)|uniprotkb:Spindle-associated membrane protein homolog(gene name synonym)|uniprotkb:T24F1.2(orf name)|uniprotkb:samp-1(gene name)|psi-mi:samp-1(display_short) psi-mi:q9u2z1_caeel(display_long)|uniprotkb:sec-23(gene name)|psi-mi:sec-23(display_short)|uniprotkb:CELE_Y113G7A.3(orf name)|uniprotkb:Y113G7A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458511|imex:IM-11985-288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496416.1|wormbase:T24F1.2|ensemblmetazoa:T24F1.2.1(transcript)|ensemblmetazoa:WBGene00011994(gene)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR018617|interpro:IPR040041|go:"GO:0005639"(integral component of nuclear inner membrane)|dip:DIP-24366N reactome:R-CEL-983170|reactome:R-CEL-5694530|reactome:R-CEL-204005|refseq:NP_507877.1|wormbase:Y113G7A.3|interpro:IPR007123(Gelsolin region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|ensemblmetazoa:WBGene00004754(gene)|ensemblmetazoa:Y113G7A.3.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:QdowhtFqJuhARa50QbUTk2GlgDw6239 rogid:TNoDPnGPQZoy+YFLVjfOYicIfls6239 intact-crc:5AD3AE85BDBBEA78|rigid:DcnxZYTUuhs85Uk3YL4wzqGuLMY false sufficient binding region:401-497("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:Q9N5U1 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-2005375|ensemblmetazoa:T22F3.3a.1 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:q9n5u1_caeel(display_long)|uniprotkb:pygl-1(gene name)|psi-mi:pygl-1(display_short)|uniprotkb:CELE_T22F3.3(orf name)|uniprotkb:T22F3.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458485|imex:IM-11985-286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_504007.1|wormbase:T22F3.3a|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|reactome:R-CEL-70221|interpro:IPR035090|ensemblmetazoa:T22F3.3a.1(transcript)|ensemblmetazoa:WBGene00020696(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:hxlfa3e+4GTuwc4kabxrVxbDecs6239 intact-crc:59300BA624A1E66F|rigid:8orRRXCzlbsws+vjS3UNSYG0VpY false sufficient binding region:403-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:Q20818 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-6458495|ensemblmetazoa:F55C5.4.1 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:q20818_caeel(display_long)|uniprotkb:F55C5.4(orf name)|uniprotkb:capg-2(gene name)|psi-mi:capg-2(display_short)|uniprotkb:CELE_F55C5.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458501|imex:IM-11985-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) ensemblmetazoa:F55C5.4.1(transcript)|ensemblmetazoa:WBGene00010093(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|reactome:R-CEL-2299718|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024741|refseq:NP_506080.1|wormbase:F55C5.4 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:znPR3oBwbnIIg6O5HlM4gCxAOSE6239 intact-crc:970EB714533CD23E|rigid:5Z5pTEiI8Txj9pwR1o223t2el/U false sufficient binding region:403-468("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30640 uniprotkb:Q18318 intact:EBI-2002595|ensemblmetazoa:R08D7.1.1 intact:EBI-326762|ensemblmetazoa:C30B5.4.1 psi-mi:bud13_caeel(display_long)|uniprotkb:R08D7.1(orf name) psi-mi:q18318_caeel(display_long)|uniprotkb:rbmx-2(gene name)|psi-mi:rbmx-2(display_short)|uniprotkb:C30B5.4(orf name)|uniprotkb:CELE_C30B5.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458521|imex:IM-11985-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498982.1|wormbase:R08D7.1|interpro:IPR018609|ensemblmetazoa:R08D7.1.1(transcript)|ensemblmetazoa:WBGene00011142(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0070274"(RES complex) refseq:NP_495237.1|wormbase:C30B5.4|ensemblmetazoa:WBGene00016245(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C30B5.4.1(transcript)|dip:DIP-26943N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:dLP4vgxP5KCPHP9rJDHEVQLHMyw6239 rogid:hnPi4Q/Z/uSY1xDRSQwr2mDxfjQ6239 intact-crc:4747D3ABE4094031|rigid:u1yYIttQ5YzNzTXArtTXaiM4H5c false sufficient binding region:401-458("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23368 uniprotkb:Q9U2Z1 intact:EBI-2005715|ensemblmetazoa:ZC518.2.1 intact:EBI-2006699|ensemblmetazoa:Y113G7A.3.1 psi-mi:q23368_caeel(display_long)|uniprotkb:sec-24.2(gene name)|psi-mi:sec-24.2(display_short)|uniprotkb:CELE_ZC518.2(orf name)|uniprotkb:ZC518.2(orf name) psi-mi:q9u2z1_caeel(display_long)|uniprotkb:sec-23(gene name)|psi-mi:sec-23(display_short)|uniprotkb:CELE_Y113G7A.3(orf name)|uniprotkb:Y113G7A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458531|imex:IM-11985-290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502354.2|wormbase:ZC518.2|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|reactome:R-CEL-204005|reactome:R-CEL-5694530|reactome:R-CEL-983170|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|ensemblmetazoa:WBGene00004756(gene)|ensemblmetazoa:ZC518.2.1(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) reactome:R-CEL-983170|reactome:R-CEL-5694530|reactome:R-CEL-204005|refseq:NP_507877.1|wormbase:Y113G7A.3|interpro:IPR007123(Gelsolin region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|ensemblmetazoa:WBGene00004754(gene)|ensemblmetazoa:Y113G7A.3.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:JsItDGj2camp6kG40w0YugYNrlY6239 rogid:TNoDPnGPQZoy+YFLVjfOYicIfls6239 intact-crc:798A36272E66015B|rigid:68quwHsH+7Ha13VOM9X9aLC2C+g false sufficient binding region:400-671("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2D9 uniprotkb:Q95Y13 intact:EBI-313125|ensemblmetazoa:Y46G5A.31.1 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 psi-mi:gys_caeel(display_long)|uniprotkb:Y46G5A.31(orf name)|uniprotkb:gsy-1(gene name)|psi-mi:gsy-1(display_short) psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458561|imex:IM-11985-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496736.1|wormbase:Y46G5A.31|reactome:R-CEL-3322077|ensemblmetazoa:WBGene00001793(gene)|ensemblmetazoa:Y46G5A.31.1(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:4QLB|dip:DIP-26557N ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b+SLtpyJP/vLcnk35dGAJgRcz946239 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 intact-crc:20CC85E981BA6FDC|rigid:4CLo3s7410EIdBhSykJAmwQJE1s false sufficient binding region:400-598("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20351 uniprotkb:Q9U2D9 intact:EBI-2003656|uniprotkb:Q8T8N1|ensemblmetazoa:F42G9.8.1 intact:EBI-313125|ensemblmetazoa:Y46G5A.31.1 psi-mi:tpstb_caeel(display_long)|uniprotkb:Tyrosylprotein sulfotransferase(gene name synonym)|uniprotkb:F42G9.8(orf name)|uniprotkb:tpst-2(gene name)|psi-mi:tpst-2(display_short) psi-mi:gys_caeel(display_long)|uniprotkb:Y46G5A.31(orf name)|uniprotkb:gsy-1(gene name)|psi-mi:gsy-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458541|imex:IM-11985-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497256.1|wormbase:F42G9.8|interpro:IPR026634|interpro:IPR027417|ensemblmetazoa:F42G9.8.1(transcript)|ensemblmetazoa:WBGene00018365(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006478"(peptidyl-tyrosine sulfation)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0008476"(protein-tyrosine sulfotransferase activity) refseq:NP_496736.1|wormbase:Y46G5A.31|reactome:R-CEL-3322077|ensemblmetazoa:WBGene00001793(gene)|ensemblmetazoa:Y46G5A.31.1(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:4QLB|dip:DIP-26557N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:S6qylnnMtTn+mWQWGCSzFCCY4/s6239 rogid:b+SLtpyJP/vLcnk35dGAJgRcz946239 intact-crc:5A36A8667035C899|rigid:X2vrCeUsFOB73TVYWp3gYbvXogo false - sufficient binding region:400-598("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2D9 uniprotkb:G5EFA2 intact:EBI-313125|ensemblmetazoa:Y46G5A.31.1 intact:EBI-328435|ensemblmetazoa:T27F2.3.1 psi-mi:gys_caeel(display_long)|uniprotkb:Y46G5A.31(orf name)|uniprotkb:gsy-1(gene name)|psi-mi:gsy-1(display_short) psi-mi:bir1_caeel(display_long)|uniprotkb:bir-1(gene name)|psi-mi:bir-1(display_short)|uniprotkb:Baculoviral IAP repeat-containing protein bir-1(gene name synonym)|uniprotkb:T27F2.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458551|imex:IM-11985-292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496736.1|wormbase:Y46G5A.31|reactome:R-CEL-3322077|ensemblmetazoa:WBGene00001793(gene)|ensemblmetazoa:Y46G5A.31.1(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:4QLB|dip:DIP-26557N uniprotkb:Q22837(uniprot-removed-ac)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|refseq:NP_505949.1|ensemblmetazoa:T27F2.3.1(transcript)|ensemblmetazoa:WBGene00000249(gene)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016573"(histone acetylation)|go:"GO:0018991"(oviposition)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030496"(midbody)|wormbase:T27F2.3|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040039"(inductive cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b+SLtpyJP/vLcnk35dGAJgRcz946239 rogid:UuKWa2EfGH/bNR+k86799sBFhrI6239 intact-crc:C253507E32E9191F|rigid:AOn4CXriNKm5r0qWbz4m1s3Xd4I false sufficient binding region:400-598("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ04 uniprotkb:Q95005 intact:EBI-313218|ensemblmetazoa:M03D4.1c.1 intact:EBI-316796|ensemblmetazoa:C36B1.4.1|ensemblmetazoa:C36B1.4.2 psi-mi:q8mq04_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:M03D4.1(orf name)|uniprotkb:CELE_M03D4.1(orf name) psi-mi:psa7_caeel(display_long)|uniprotkb:pas-4(gene name)|psi-mi:pas-4(display_short)|uniprotkb:C36B1.4(orf name)|uniprotkb:Proteasome subunit alpha 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458591|imex:IM-11985-296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023311.1|wormbase:M03D4.1c|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR032384|ensemblmetazoa:M03D4.1c.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR027417|interpro:IPR038105|interpro:IPR027640 reactome:R-CEL-5689603|reactome:R-CEL-5689880|refseq:NP_492360.1|wormbase:C36B1.4|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:C36B1.4.1(transcript)|ensemblmetazoa:C36B1.4.2(transcript)|ensemblmetazoa:WBGene00003925(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:qAci4uz+7AlWxi0T8ZVymtdA6WU6239 rogid:WWXt5jeuKRCX9WomT3Wqk45PRIc6239 intact-crc:CB404424A3A1C794|rigid:5dAuCAJfrMvS0+j5HtmDbgYvXh0 false sufficient binding region:399-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2D9 uniprotkb:P34286 intact:EBI-313125|ensemblmetazoa:Y46G5A.31.1 intact:EBI-313778|uniprotkb:Q9BMU3|ensemblmetazoa:C02F5.9.1 psi-mi:gys_caeel(display_long)|uniprotkb:Y46G5A.31(orf name)|uniprotkb:gsy-1(gene name)|psi-mi:gsy-1(display_short) psi-mi:psb1_caeel(display_long)|uniprotkb:pbs-6(gene name)|psi-mi:pbs-6(display_short)|uniprotkb:C02F5.9(orf name)|uniprotkb:Proteasome subunit beta 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458571|imex:IM-11985-294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496736.1|wormbase:Y46G5A.31|reactome:R-CEL-3322077|ensemblmetazoa:WBGene00001793(gene)|ensemblmetazoa:Y46G5A.31.1(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:4QLB|dip:DIP-26557N reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_498806.1|wormbase:C02F5.9|reactome:R-CEL-5632684|ensemblmetazoa:C02F5.9.1(transcript)|ensemblmetazoa:WBGene00003952(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-24619N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b+SLtpyJP/vLcnk35dGAJgRcz946239 rogid:g54+kg5aHsaQMTBH6xZ9h0/20XQ6239 intact-crc:C915A5756AF1B4C0|rigid:4DmjAFxwf7s88jrcKtL+DXHjf2I false sufficient binding region:400-532("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ04 uniprotkb:Q95YF3 intact:EBI-313218|ensemblmetazoa:M03D4.1c.1 intact:EBI-314525|ensemblmetazoa:C07H6.5.1 psi-mi:q8mq04_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:M03D4.1(orf name)|uniprotkb:CELE_M03D4.1(orf name) psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458581|imex:IM-11985-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023311.1|wormbase:M03D4.1c|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR032384|ensemblmetazoa:M03D4.1c.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR027417|interpro:IPR038105|interpro:IPR027640 refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:qAci4uz+7AlWxi0T8ZVymtdA6WU6239 rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239 intact-crc:14F7E975AAF1D142|rigid:Os/5rn7h0raKe9h/Ep8oYTwz6T0 false sufficient binding region:399-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17796 uniprotkb:O62333 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458621|imex:IM-11985-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 intact-crc:53E233288117036F|rigid:MqbaWG6eGr1Zm5nhuO00+OQavxE false sufficient binding region:398-537("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8MQ04 uniprotkb:Q8MQ04 intact:EBI-313218|ensemblmetazoa:M03D4.1c.1 intact:EBI-313218|ensemblmetazoa:M03D4.1c.1 psi-mi:q8mq04_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:M03D4.1(orf name)|uniprotkb:CELE_M03D4.1(orf name) psi-mi:q8mq04_caeel(display_long)|uniprotkb:zen-4(gene name)|psi-mi:zen-4(display_short)|uniprotkb:M03D4.1(orf name)|uniprotkb:CELE_M03D4.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458601|imex:IM-11985-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023311.1|wormbase:M03D4.1c|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR032384|ensemblmetazoa:M03D4.1c.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR027417|interpro:IPR038105|interpro:IPR027640 refseq:NP_001023311.1|wormbase:M03D4.1c|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR032384|ensemblmetazoa:M03D4.1c.1(transcript)|ensemblmetazoa:WBGene00006974(gene)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031991"(regulation of actomyosin contractile ring contraction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR027417|interpro:IPR038105|interpro:IPR027640 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:qAci4uz+7AlWxi0T8ZVymtdA6WU6239 rogid:qAci4uz+7AlWxi0T8ZVymtdA6WU6239 intact-crc:0500FA7A000B106D|rigid:1TnaAL5BSM4jccEXINfIvpmCpJg false - sufficient binding region:399-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:G5ECY0 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458611|imex:IM-11985-298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:81EB214A1E0C3F83|rigid:0E1pze79xFA5aB7nu/5YTevZX/Q false - sufficient binding region:399-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21831 uniprotkb:Q09996 intact:EBI-360213|ensemblmetazoa:R07E5.3.1 intact:EBI-2004870|ensemblmetazoa:R74.1.1|ensemblmetazoa:R74.1.2 psi-mi:q21831_caeel(display_long)|uniprotkb:snfc-5(gene name)|psi-mi:snfc-5(display_short)|uniprotkb:CELE_R07E5.3(orf name)|uniprotkb:R07E5.3(orf name) psi-mi:sylc_caeel(display_long)|uniprotkb:lars-1(gene name)|psi-mi:lars-1(display_short)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)|uniprotkb:lrs-1(gene name synonym)|uniprotkb:R74.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458631|imex:IM-11985-300 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:R07E5.3.1(transcript)|ensemblmetazoa:WBGene00011111(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|refseq:NP_497890.1|wormbase:R07E5.3|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|reactome:R-CEL-8939243 refseq:NP_497837.1|wormbase:R74.1|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR004493(Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|ensemblmetazoa:R74.1.1(transcript)|ensemblmetazoa:R74.1.2(transcript)|ensemblmetazoa:WBGene00003073(gene)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006412"(translation)|go:"GO:0006429"(leucyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:xJdCCAUyt1lmFvLa0ZpqfBxhlLQ6239 rogid:JbipRvy0JQkpJnJ3wUi7wutqjQE6239 intact-crc:97198956198FCE16|rigid:GLzbDqVZ43ZKH/6YiIYIUNOSWc0 false - sufficient binding region:398-534("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XTF3-3 uniprotkb:P55853 intact:EBI-6458160|ensemblmetazoa:F49E11.1c.1 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:q9xtf3-3(display_long)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:F49E11.1(orf name)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458641|imex:IM-11985-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2005616(isoform-parent)|ensemblmetazoa:F49E11.1c.1(transcript)|ensemblmetazoa:WBGene00003150(gene) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:q+r0vN0DzQfPQs5H4lzQOgECK1k6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:8451C7A68EB61CD2|rigid:7iE50wUMwLDIUhlV/MurG8c07nA false - sufficient binding region:3-91("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4P2 uniprotkb:P55853 intact:EBI-6458671|ensemblmetazoa:ZK121.1a.1 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:q9n4p2_caeel(display_long)|uniprotkb:ZK121.1(orf name)|uniprotkb:glrx-21(gene name)|psi-mi:glrx-21(display_short)|uniprotkb:CELE_ZK121.1(orf name) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458676|imex:IM-11985-304 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022663(gene)|ensemblmetazoa:ZK121.1a.1(transcript)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR014025(Glutaredoxin subgroup)|refseq:NP_001040891.1|wormbase:ZK121.1a|interpro:IPR036249 reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:grf21uXIxxiGjrIKh9vZSesGxTI6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:C6A7B370EE94EB3F|rigid:MAaFFSKAlSA6trYJY3k4c3ZhSns false - sufficient binding region:3-91("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21021 uniprotkb:P55853 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458651|imex:IM-11985-302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:309C3F76196BCAC1|rigid:pETVU2jTih2UPF+GMdjkaEmlB0A false - sufficient binding region:3-91("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:Q9N5U1 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-2005375|ensemblmetazoa:T22F3.3a.1 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:q9n5u1_caeel(display_long)|uniprotkb:pygl-1(gene name)|psi-mi:pygl-1(display_short)|uniprotkb:CELE_T22F3.3(orf name)|uniprotkb:T22F3.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458661|imex:IM-11985-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 refseq:NP_504007.1|wormbase:T22F3.3a|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|reactome:R-CEL-70221|interpro:IPR035090|ensemblmetazoa:T22F3.3a.1(transcript)|ensemblmetazoa:WBGene00020696(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:hxlfa3e+4GTuwc4kabxrVxbDecs6239 intact-crc:1620E5F391BCEE44|rigid:7akuTo5twez5XAox+xTaYu/uzyc false sufficient binding region:3-91("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEK3 uniprotkb:Q9NAN2-1 intact:EBI-325994|ensemblmetazoa:T09E8.1c.1|intact:EBI-2918134|uniprotkb:A0A0M3UPV7|uniprotkb:G5EBN2|uniprotkb:G5EBP7|uniprotkb:G5EC74|uniprotkb:G5EE58|uniprotkb:N1NSE8|uniprotkb:Q8I4G1|uniprotkb:Q9XVL5 intact:EBI-6458686|ensemblmetazoa:T26E3.3a.1|ensemblmetazoa:T26E3.3a.2 psi-mi:noca1_caeel(display_long)|uniprotkb:T09E8.1(orf name)|uniprotkb:noca-1(gene name)|psi-mi:noca-1(display_short) psi-mi:q9nan2-1(display_long)|uniprotkb:T26E3.3(orf name)|uniprotkb:par-6(gene name)|psi-mi:par-6(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458691|imex:IM-11985-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8I0T9(uniprot-removed-ac)|wormbase:T09E8.1c|refseq:NP_872199.2|ensemblmetazoa:T09E8.1c.1(transcript)|ensemblmetazoa:WBGene00011647(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0007281"(germ cell development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031122"(cytoplasmic microtubule organization)|refseq:NP_001041165.1|refseq:NP_001294691.1|refseq:NP_001303706.1|refseq:NP_506274.1|refseq:NP_506275.2|refseq:NP_506276.2|refseq:NP_872200.1|refseq:NP_872201.2|wormbase:T09E8.1a|wormbase:T09E8.1b|wormbase:T09E8.1d|wormbase:T09E8.1e|wormbase:T09E8.1f|wormbase:T09E8.1g|wormbase:T09E8.1h|wormbase:T09E8.1i intact:EBI-318782(isoform-parent)|ensemblmetazoa:T26E3.3a.1(transcript)|ensemblmetazoa:T26E3.3a.2(transcript)|ensemblmetazoa:WBGene00003921(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:DghE2eZm+hdv+gkEe/DOmgzhYgk6239 rogid:CWjdm5DAUzsqFaqTydp1Q/EJobU6239 intact-crc:B2E8C77B012736C1|rigid:GWcOdRI4ss/2E/DoUuBUMa8sv3o false sufficient binding region:384-922("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6458701 uniprotkb:Q9NES7 intact:EBI-6306432 intact:EBI-312701|ensemblmetazoa:Y39B6A.1.1 psi-mi:ebi6306432(display_short)|psi-mi:EBI-6458701(display_long)|intact:Y57A10A.24x(author assigned name) psi-mi:q9nes7_caeel(display_long)|uniprotkb:Y39B6A.1(orf name)|uniprotkb:CELE_Y39B6A.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458705|imex:IM-11985-306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_741698.1|wormbase:Y39B6A.1|ensemblmetazoa:WBGene00012664(gene)|ensemblmetazoa:Y39B6A.1.1(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|dip:DIP-25463N psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:6zMeRngB/ofLajp54qhQGJW0o+86239 intact-crc:2B1C1DF09D52A4D8 false - sufficient binding region:382-735("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q7JNG1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2003312|ensemblmetazoa:F27C1.7b.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q7jng1_caeel(display_long)|uniprotkb:atp-3(gene name)|psi-mi:atp-3(display_short)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)|uniprotkb:CELE_F27C1.7(orf name)|uniprotkb:F27C1.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458735|imex:IM-11985-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_001021421.1|wormbase:F27C1.7b|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR026015|reactome:R-CEL-163210|reactome:R-CEL-8949613|ensemblmetazoa:F27C1.7b.1(transcript)|ensemblmetazoa:WBGene00000230(gene)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:48H/lbO1bvZYUSNsQeH1aMGLJJw6239 intact-crc:2CC0ADAEBE38BC86|rigid:y0+jn022HkskLKKjuhuvSdnR5cg false sufficient binding region:377-645("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91175 uniprotkb:Q9XVU8 intact:EBI-2415020|ensemblmetazoa:C50F2.3.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:p91175_caeel(display_long)|uniprotkb:syf-1(gene name)|psi-mi:syf-1(display_short)|uniprotkb:C50F2.3(orf name)|uniprotkb:CELE_C50F2.3(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458715|imex:IM-11985-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491250.1|wormbase:C50F2.3|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-72163|ensemblmetazoa:C50F2.3.1(transcript)|ensemblmetazoa:WBGene00016837(gene)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:TJCW0aRExDbLbOr1D0eUTR8CTO86239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:3D147C9A7201A6BC|rigid:dYtj/PpQFxs1JvGsJe/UrfqMqtI false - sufficient binding region:377-645("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:P91283 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-313421|ensemblmetazoa:F27C1.7a.1|ensemblmetazoa:F27C1.7a.2|ensemblmetazoa:F27C1.7a.3|ensemblmetazoa:F27C1.7a.4|ensemblmetazoa:F27C1.7a.5 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:p91283_caeel(display_long)|uniprotkb:atp-3(gene name)|psi-mi:atp-3(display_short)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)|uniprotkb:CELE_F27C1.7(orf name)|uniprotkb:F27C1.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458725|imex:IM-11985-308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_001021420.1|wormbase:F27C1.7a|ensemblmetazoa:F27C1.7a.1(transcript)|ensemblmetazoa:F27C1.7a.2(transcript)|ensemblmetazoa:F27C1.7a.3(transcript)|ensemblmetazoa:F27C1.7a.4(transcript)|ensemblmetazoa:F27C1.7a.5(transcript)|ensemblmetazoa:WBGene00000230(gene)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR026015|dip:DIP-26184N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:1NTGNlc9wMqgCOORpCDkRfohA3Y6239 intact-crc:C8378035F22E0D29|rigid:4WfWBUJC2EpqT6p3/JIxP5/c0WU false sufficient binding region:377-645("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6457133 uniprotkb:Q9XVU8 intact:EBI-6306363 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:ebi6306363(display_short)|psi-mi:EBI-6457133(display_long)|intact:F39H11.2x(author assigned name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458745|imex:IM-11985-310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:2D8A4FE592274936 false - sufficient binding region:377-645("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q9U3C1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2004353|ensemblmetazoa:K07F5.13b.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q9u3c1_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458755|imex:IM-11985-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_501771.1|wormbase:K07F5.13b|interpro:IPR024864|interpro:IPR025712|interpro:IPR025574|ensemblmetazoa:K07F5.13b.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:PBUFj0HXUAAcVEWkwfLNogGoZNQ6239 intact-crc:4262106F9E1C8E0A|rigid:tcPI7oZJAEx0tuTLOBVn1Dr54QE false sufficient binding region:377-645("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20052 uniprotkb:P34514 intact:EBI-314913|ensemblmetazoa:F35G12.9.1|ensemblmetazoa:F35G12.9.2 intact:EBI-321211|uniprotkb:P34513|ensemblmetazoa:K06H7.6.1 psi-mi:apc11_caeel(display_long)|uniprotkb:apc-11(gene name)|psi-mi:apc-11(display_short)|uniprotkb:F35G12.9(orf name) psi-mi:anc2_caeel(display_long)|uniprotkb:apc-2(gene name)|psi-mi:apc-2(display_short)|uniprotkb:K06H7.6/K06H7.5(orf name)|uniprotkb:Cyclosome subunit 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458785|imex:IM-11985-314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497937.1|wormbase:F35G12.9|ensemblmetazoa:F35G12.9.1(transcript)|ensemblmetazoa:F35G12.9.2(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|ensemblmetazoa:WBGene00000145(gene)|dip:DIP-24995N|reactome:R-CEL-983168 refseq:NP_498762.2|wormbase:K06H7.6|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|ensemblmetazoa:K06H7.6.1(transcript)|interpro:IPR014786(Anaphase promoting complex subunit 2)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|ensemblmetazoa:WBGene00000143(gene)|interpro:IPR036317|interpro:IPR036388|reactome:R-CEL-983168|interpro:IPR044554 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:11SdvWjkFNUyCv4arePb6BEXKEg6239 rogid:5aEjMp7tIE0ClHdaPpdw0mJBHmg6239 intact-crc:3E8C39AAD6FB1012|rigid:Z7b8uy/rKw863jbqVMeak7K41GY false - sufficient binding region:376-731("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q9XVU8 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458765|imex:IM-11985-312 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:D9684BB61FB74BE5|rigid:hqz0HoRK+6bwAKmeOZMiirGc+xY false - sufficient binding region:377-645("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:P91457 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458775|imex:IM-11985-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:00F4D1E57D45C826|rigid:wuSQ1DQNZAjfnyIiB/aAaw/dgkw false sufficient binding region:377-645("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45734 uniprotkb:Q19713 intact:EBI-315958|uniprotkb:H9G333|ensemblmetazoa:T03E6.7a.1 intact:EBI-6458795|ensemblmetazoa:F22B5.9.1 psi-mi:cpl1_caeel(display_long)|uniprotkb:cpl-1(gene name)|psi-mi:cpl-1(display_short)|uniprotkb:T03E6.7(orf name) psi-mi:syfb_caeel(display_long)|uniprotkb:fars-3(gene name)|psi-mi:fars-3(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:frs-2(gene name synonym)|uniprotkb:F22B5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458800|imex:IM-11985-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256718.1|reactome:R-CEL-6798695|refseq:NP_001256719.1|wormbase:T03E6.7b|wormbase:T03E6.7a|reactome:R-CEL-1442490|reactome:R-CEL-1474228|reactome:R-CEL-1592389|reactome:R-CEL-2132295|reactome:R-CEL-8939242|ensemblmetazoa:T03E6.7a.1(transcript)|ensemblmetazoa:WBGene00000776(gene)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006955"(immune response)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032010"(phagolysosome)|go:"GO:0036019"(endolysosome)|go:"GO:0042718"(yolk granule)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070613"(regulation of protein processing)|go:"GO:1903188"(positive regulation of vitellogenesis)|go:"GO:1905691"(lipid droplet disassembly)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013201(Proteinase inhibitor I29, cathepsin propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|interpro:IPR039417|dip:DIP-26616N ensemblmetazoa:F22B5.9.1(transcript)|ensemblmetazoa:WBGene00001498(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR040659|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|refseq:NP_495785.1|wormbase:F22B5.9|interpro:IPR041616 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Ux0JymZ//AEo8huJfvZ9R38pnTs6239 rogid:vnO3fcS4LkBf8htippBIQGUn4M06239 intact-crc:146F058C7704FA7A|rigid:iR5h1dU+KCxt19lXXu5+7Pf3WGw false sufficient binding region:37-337("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16516 uniprotkb:Q03604 intact:EBI-2005361|ensemblmetazoa:T05H4.11.1|ensemblmetazoa:T05H4.11.2 intact:EBI-312231|ensemblmetazoa:T23G5.1.2|ensemblmetazoa:T23G5.1.1 psi-mi:o16516_caeel(display_long)|uniprotkb:CELE_T05H4.11(orf name)|uniprotkb:T05H4.11(orf name) psi-mi:rir1_caeel(display_long)|uniprotkb:rnr-1(gene name)|psi-mi:rnr-1(display_short)|uniprotkb:T23G5.1(orf name)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458810|imex:IM-11985-316 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504632.1|wormbase:T05H4.11a|ensemblmetazoa:T05H4.11.1(transcript)|ensemblmetazoa:T05H4.11.2(transcript)|ensemblmetazoa:WBGene00020274(gene) ensemblmetazoa:T23G5.1.1(transcript)|ensemblmetazoa:T23G5.1.2(transcript)|ensemblmetazoa:WBGene00004391(gene)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|refseq:NP_499039.1|wormbase:T23G5.1|reactome:R-CEL-499943|dip:DIP-26889N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:lArnU+WlAKlctSAI2MaY1jZdOi46239 rogid:bfWihc13lxc9ymkt/81/EEYxmZg6239 intact-crc:54A5F564BE732D9A|rigid:L9LwFr/dahW7JWNm7J5/PQ/dw60 false sufficient binding region:37-210("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q21127 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-317734|ensemblmetazoa:K02B9.2.1 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:q21127_caeel(display_long)|uniprotkb:meg-2(gene name)|psi-mi:meg-2(display_short)|uniprotkb:K02B9.2(orf name)|uniprotkb:CELE_K02B9.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458820|imex:IM-11985-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) refseq:NP_510318.2|wormbase:K02B9.2|ensemblmetazoa:K02B9.2.1(transcript)|ensemblmetazoa:WBGene00010493(gene)|go:"GO:0043186"(P granule)|go:"GO:1903864"(P granule disassembly)|dip:DIP-27499N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:y7HxloUvGK6UyM1AkWQi2qCR8jw6239 intact-crc:064E8A371D9059F6|rigid:TfoPBsmsx/saFwmCPHdxFKao6l0 false - sufficient binding region:370-819("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:Q21502 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-319858|uniprotkb:Q95VF1|ensemblmetazoa:M04B2.1.1 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:mep1_caeel(display_long)|uniprotkb:M04B2.1(orf name)|uniprotkb:Nuclear zinc finger protein(gene name synonym)|uniprotkb:mep-1(gene name)|psi-mi:mep-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458830|imex:IM-11985-318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 refseq:NP_502173.2|wormbase:M04B2.1|ensemblmetazoa:M04B2.1.1(transcript)|ensemblmetazoa:WBGene00003218(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:5BfQpmdZPLVYpnz8eRO3Ubzxqbg6239 intact-crc:CAE0BD97830BBDB9|rigid:r+1AaV/oNN607VZ5o4JZ2b9ukXY false - sufficient binding region:36-870("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q8MXR2 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-327674|ensemblmetazoa:Y73B6BL.33a.1 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:q8mxr2_caeel(display_long)|uniprotkb:hrpf-2(gene name)|psi-mi:hrpf-2(display_short)|uniprotkb:CELE_Y73B6BL.33(orf name)|uniprotkb:Y73B6BL.33(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458840|imex:IM-11985-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) refseq:NP_741422.1|wormbase:Y73B6BL.33a|ensemblmetazoa:WBGene00022253(gene)|ensemblmetazoa:Y73B6BL.33a.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|dip:DIP-24945N|reactome:R-CEL-72163 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:vstHX9nskJYcL8v9uG44qxSW+8Q6239 intact-crc:306A3A0E2FA80F44|rigid:M41AO+s0Owj9oobI1aN1C8oR3mQ false - sufficient binding region:368-610("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2Q9 uniprotkb:Q9NAG4 intact:EBI-330089|uniprotkb:Q9Y0C2|ensemblmetazoa:Y18D10A.5.1 intact:EBI-2005767|uniprotkb:Q9U8K0|ensemblmetazoa:Y48C3A.7.1 psi-mi:gsk3_caeel(display_long)|uniprotkb:gsk-3(gene name)|psi-mi:gsk-3(display_short)|uniprotkb:sgg-1(gene name synonym)|uniprotkb:Y18D10A.5(orf name) psi-mi:mac1_caeel(display_long)|uniprotkb:mac-1(gene name)|psi-mi:mac-1(display_short)|uniprotkb:Member of AAA family that binds ced-4(gene name synonym)|uniprotkb:Y48C3A.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458850|imex:IM-11985-320 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493243.1|wormbase:Y18D10A.5|mint:Q9U2Q9|dip:DIP-25216N|ensemblmetazoa:WBGene00001746(gene)|ensemblmetazoa:Y18D10A.5.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0070986"(left/right axis specification)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-CEL-195253|reactome:R-CEL-196299|reactome:R-CEL-3371453|reactome:R-CEL-399956|reactome:R-CEL-4641262 refseq:NP_496814.1|wormbase:Y48C3A.7|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR031996|interpro:IPR038100|interpro:IPR027417|interpro:IPR041569|ensemblmetazoa:WBGene00003119(gene)|ensemblmetazoa:Y48C3A.7.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0019915"(lipid storage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061063"(positive regulation of nematode larval development)|go:"GO:1990275"(preribosome binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:nP6ix+jIij252trr3joE6r80xYo6239 rogid:W9NHEAQ+fndSqiCE31txhbiIc5s6239 intact-crc:5A7D6A48140E0ABD|rigid:Tf4j2QxRiccZb6AA72l3Cm2ktFo false - sufficient binding region:36-813("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23457 uniprotkb:Q02335 intact:EBI-1998112|uniprotkb:Q8WSQ1|ensemblmetazoa:ZK287.5.1|ensemblmetazoa:ZK287.5.2 intact:EBI-331682|ensemblmetazoa:ZK370.8.1 psi-mi:rbx1_caeel(display_long)|uniprotkb:rbx-1(gene name)|psi-mi:rbx-1(display_short)|uniprotkb:Ce-rbx-1(gene name synonym)|uniprotkb:ZK287.5(orf name) psi-mi:tom70_caeel(display_long)|uniprotkb:tomm-70(gene name)|psi-mi:tomm-70(display_short)|uniprotkb:Translocase of outer mitochondrial membrane 70(gene name synonym)|uniprotkb:ZK370.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458860|imex:IM-11985-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505496.1|wormbase:ZK287.5|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:Q23457|ensemblmetazoa:WBGene00004320(gene)|ensemblmetazoa:ZK287.5.1(transcript)|ensemblmetazoa:ZK287.5.2(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0051301"(cell division)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|reactome:R-CEL-110314|reactome:R-CEL-1234176|reactome:R-CEL-195253|reactome:R-CEL-5632684|reactome:R-CEL-5696394|reactome:R-CEL-5696395|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-68949|reactome:R-CEL-8854050|reactome:R-CEL-8932339|reactome:R-CEL-8939902|reactome:R-CEL-8951664|reactome:R-CEL-983168|reactome:R-CEL-4641258 wormbase:ZK370.8|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|ensemblmetazoa:ZK370.8.1(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensemblmetazoa:WBGene00022722(gene)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0098586"(cellular response to virus)|refseq:NP_498932.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:K9YFXD2x8iuzCtYyPx/bYHJnT4Q6239 rogid:LUQFn5pgk7KoDtKsiEAWESWDkgw6239 intact-crc:4ABE10409A18B18E|rigid:0s0V2xavqIrz3rmABbGrD03NSU8 false - sufficient binding region:36-569("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECU1 uniprotkb:Q18223 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 intact:EBI-2003744|ensemblmetazoa:C26E6.5.1 psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:fbsp1_caeel(display_long)|uniprotkb:fsn-1(gene name)|psi-mi:fsn-1(display_short)|uniprotkb:F-box synaptic protein 1(gene name synonym)|uniprotkb:C26E6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458870|imex:IM-11985-322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 refseq:NP_498046.1|wormbase:C26E6.5|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035784|interpro:IPR036047|interpro:IPR043136|ensemblmetazoa:C26E6.5.1(transcript)|ensemblmetazoa:WBGene00001499(gene)|go:"GO:0002020"(protease binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0040024"(dauer larval development)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0098793"(presynapse)|go:"GO:1900073"(regulation of neuromuscular synaptic transmission)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1900182"(positive regulation of protein localization to nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 rogid:Voig45zw30LCvvEucQt9DkmQFnI6239 intact-crc:DE08B338EFC77520|rigid:6MNkbEPY8QUF8GAZxo8hZ65jsXM false - sufficient binding region:36-332("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19699 uniprotkb:Q19130 intact:EBI-6458880|ensemblmetazoa:F22B3.4.1|ensemblmetazoa:F22B3.4.2 intact:EBI-331451|ensemblmetazoa:F07A11.2a.1|ensemblmetazoa:F07A11.2a.2|ensemblmetazoa:F07A11.2a.3|ensemblmetazoa:F07A11.2a.4 psi-mi:q19699_caeel(display_long)|uniprotkb:gfat-2(gene name)|psi-mi:gfat-2(display_short)|uniprotkb:CELE_F22B3.4(orf name)|uniprotkb:F22B3.4(orf name) psi-mi:q19130_caeel(display_long)|uniprotkb:gfat-1(gene name)|psi-mi:gfat-1(display_short)|uniprotkb:CELE_F07A11.2(orf name)|uniprotkb:F07A11.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458884|imex:IM-11985-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F22B3.4.1(transcript)|ensemblmetazoa:F22B3.4.2(transcript)|ensemblmetazoa:WBGene00009035(gene)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|interpro:IPR035466|interpro:IPR035490|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR017932|refseq:NP_502156.1|wormbase:F22B3.4|reactome:R-CEL-446210|interpro:IPR029055 reactome:R-CEL-446210|refseq:NP_496480.1|wormbase:F07A11.2a|dip:DIP-26050N|ensemblmetazoa:F07A11.2a.1(transcript)|ensemblmetazoa:F07A11.2a.2(transcript)|ensemblmetazoa:F07A11.2a.3(transcript)|ensemblmetazoa:F07A11.2a.4(transcript)|ensemblmetazoa:WBGene00008546(gene)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LGYyHFF+9bf9MZIR4GEj8t79x686239 rogid:EXxUvmcQTTl6qV61gXGgFNAZHAo6239 intact-crc:8074A11911B435AE|rigid:ZqARn4ICeWY4efVz4IC7J5lwGhk false - sufficient binding region:361-725("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GT24 uniprotkb:Q9GRZ9 intact:EBI-323555|uniprotkb:O01903|ensemblmetazoa:F59E12.2.1|ensemblmetazoa:F59E12.2.2 intact:EBI-324591|ensemblmetazoa:Y59A8A.3.1 psi-mi:zyg1_caeel(display_long)|uniprotkb:zyg-1(gene name)|psi-mi:zyg-1(display_short)|uniprotkb:F59E12.2(orf name)|uniprotkb:Zygote defective protein 1(gene name synonym) psi-mi:q9grz9_caeel(display_long)|uniprotkb:tcc-1(gene name)|psi-mi:tcc-1(display_short)|uniprotkb:Y59A8A.3(orf name)|uniprotkb:CELE_Y59A8A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458894|imex:IM-11985-324 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495103.1|wormbase:F59E12.2|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0051225"(spindle assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|ensemblmetazoa:F59E12.2.1(transcript)|ensemblmetazoa:F59E12.2.2(transcript)|ensemblmetazoa:WBGene00006988(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0106311"|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1904779"(regulation of protein localization to centrosome)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR040733|interpro:IPR040734|rcsb pdb:4NKB|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-24892N refseq:NP_507506.1|wormbase:Y59A8A.3|ensemblmetazoa:WBGene00013340(gene)|ensemblmetazoa:Y59A8A.3.1(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0051653"(spindle localization)|dip:DIP-25516N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bW56U+tOCdP8UXKTudspR9Oi4/Q6239 rogid:e8GgSnYWpDdPmfc02b/dAC+RUeI6239 intact-crc:59A11D2516B0D0D0|rigid:zD4o81PpVwaVfSTC1qclwjBr6r0 false - sufficient binding region:360-676("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22078 uniprotkb:Q03563 intact:EBI-323051|ensemblmetazoa:T01G9.4.1|ensemblmetazoa:T01G9.4.2 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:q22078_caeel(display_long)|uniprotkb:npp-2(gene name)|psi-mi:npp-2(display_short)|uniprotkb:CELE_T01G9.4(orf name)|uniprotkb:T01G9.4(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458914|imex:IM-11985-326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492256.1|wormbase:T01G9.4|interpro:IPR011502(Nucleoporin, Nup85-like)|ensemblmetazoa:T01G9.4.1(transcript)|ensemblmetazoa:T01G9.4.2(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090435"(protein localization to nuclear envelope)|ensemblmetazoa:WBGene00003788(gene)|reactome:R-CEL-9615933 refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zeIaeaV7GOQHaMra/3zZ7xf75q46239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:DD7BCA872D03F59B|rigid:09YHo+s1nGAXHp+1krGLZxcJkYg false - sufficient binding region:356-490("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19713 uniprotkb:Q03563 intact:EBI-6458795|ensemblmetazoa:F22B5.9.1 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:syfb_caeel(display_long)|uniprotkb:fars-3(gene name)|psi-mi:fars-3(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:frs-2(gene name synonym)|uniprotkb:F22B5.9(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458904|imex:IM-11985-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F22B5.9.1(transcript)|ensemblmetazoa:WBGene00001498(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR040659|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|refseq:NP_495785.1|wormbase:F22B5.9|interpro:IPR041616 refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vnO3fcS4LkBf8htippBIQGUn4M06239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:9979013317F349D6|rigid:aLq1KR+HUHh8H9QTWCkdWHVb5u8 false - sufficient binding region:356-490("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P47207 uniprotkb:P47208 intact:EBI-896048|uniprotkb:Q22628|ensemblmetazoa:T21B10.7.1|ensemblmetazoa:T21B10.7.2|ensemblmetazoa:T21B10.7.3 intact:EBI-2005290|ensemblmetazoa:K01C8.10.1|ensemblmetazoa:K01C8.10.2 psi-mi:tcpb_caeel(display_long)|uniprotkb:cct-2(gene name)|psi-mi:cct-2(display_short)|uniprotkb:cctb(gene name synonym)|uniprotkb:T21B10.7(orf name)|uniprotkb:CCT-beta(gene name synonym) psi-mi:tcpd_caeel(display_long)|uniprotkb:cct-4(gene name)|psi-mi:cct-4(display_short)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:K01C8.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458934|imex:IM-11985-328 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_741031.1|wormbase:T21B10.7|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|reactome:R-CEL-6814122|reactome:R-CEL-390471|interpro:IPR027409|interpro:IPR027413|reactome:R-CEL-6798695|interpro:IPR027410|ensemblmetazoa:T21B10.7.1(transcript)|ensemblmetazoa:T21B10.7.2(transcript)|ensemblmetazoa:T21B10.7.3(transcript)|ensemblmetazoa:WBGene00000378(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding) refseq:NP_495750.1|wormbase:K01C8.10|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027410|reactome:R-CEL-390471|reactome:R-CEL-6814122|interpro:IPR027409|interpro:IPR027413|ensemblmetazoa:K01C8.10.1(transcript)|ensemblmetazoa:K01C8.10.2(transcript)|ensemblmetazoa:WBGene00000379(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0051082"(unfolded protein binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:K6PKjnW31GjKiGxb3asMUTz2RLI6239 rogid:bTJ7n/Wevkqr5K0jvr2AZzRR6vs6239 intact-crc:ACFCA0DDD9F6771E|rigid:KjXciDHgyNFm/yvWpVTLTGDiHNA false - sufficient binding region:3-540("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34331-2 uniprotkb:G5EEK3 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 intact:EBI-325994|ensemblmetazoa:T09E8.1c.1|intact:EBI-2918134|uniprotkb:A0A0M3UPV7|uniprotkb:G5EBN2|uniprotkb:G5EBP7|uniprotkb:G5EC74|uniprotkb:G5EE58|uniprotkb:N1NSE8|uniprotkb:Q8I4G1|uniprotkb:Q9XVL5 psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:noca1_caeel(display_long)|uniprotkb:T09E8.1(orf name)|uniprotkb:noca-1(gene name)|psi-mi:noca-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458944|imex:IM-11985-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) uniprotkb:Q8I0T9(uniprot-removed-ac)|wormbase:T09E8.1c|refseq:NP_872199.2|ensemblmetazoa:T09E8.1c.1(transcript)|ensemblmetazoa:WBGene00011647(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0007281"(germ cell development)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031122"(cytoplasmic microtubule organization)|refseq:NP_001041165.1|refseq:NP_001294691.1|refseq:NP_001303706.1|refseq:NP_506274.1|refseq:NP_506275.2|refseq:NP_506276.2|refseq:NP_872200.1|refseq:NP_872201.2|wormbase:T09E8.1a|wormbase:T09E8.1b|wormbase:T09E8.1d|wormbase:T09E8.1e|wormbase:T09E8.1f|wormbase:T09E8.1g|wormbase:T09E8.1h|wormbase:T09E8.1i psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:u830S0jdkV753ilx7DbxmhPocv86239 rogid:DghE2eZm+hdv+gkEe/DOmgzhYgk6239 intact-crc:76E4A0F6BA74E2FD|rigid:MXt7+ZPn8wEM1zvVB7lc43RgOk8 false - sufficient binding region:347-922("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWI6 uniprotkb:O01299 intact:EBI-317365|uniprotkb:Q7K785|ensemblmetazoa:Y54E2A.11a.1|ensemblmetazoa:Y54E2A.11a.2|ensemblmetazoa:Y54E2A.11a.3 intact:EBI-2006306|ensemblmetazoa:F09C8.2.1 psi-mi:eif3b_caeel(display_long)|uniprotkb:eif-3.B(gene name)|psi-mi:eif-3.B(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:Y54E2A.11(orf name) psi-mi:o01299_caeel(display_long)|uniprotkb:F09C8.2(orf name)|uniprotkb:CELE_F09C8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458924|imex:IM-11985-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022469.2|wormbase:Y54E2A.11a|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|refseq:NP_001022470.2|wormbase:Y54E2A.11b|ensemblmetazoa:WBGene00001225(gene)|ensemblmetazoa:Y54E2A.11a.1(transcript)|ensemblmetazoa:Y54E2A.11a.2(transcript)|ensemblmetazoa:Y54E2A.11a.3(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|dip:DIP-26989N|reactome:R-CEL-72649 refseq:NP_510635.2|wormbase:F09C8.2|interpro:IPR039884|ensemblmetazoa:F09C8.2.1(transcript)|ensemblmetazoa:WBGene00008622(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:SR037TI5QzHk7oWIA+Kc/ISHRCs6239 rogid:4slc5ODejK3YgC912WmTzPHnEw46239 intact-crc:1255226EE3869F94|rigid:nnkE+KY6qr9Auo+or93nwEt9tV0 false - sufficient binding region:354-762("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34808 uniprotkb:Q94420 intact:EBI-323248|intact:EBI-521368|uniprotkb:Q8I4G6|ensemblmetazoa:T01G9.5a.1 intact:EBI-320790|uniprotkb:Q94139|ensemblmetazoa:ZK858.4a.1 psi-mi:ktna1_caeel(display_long)|uniprotkb:mei-1(gene name)|psi-mi:mei-1(display_short)|uniprotkb:Katanin p60 ATPase-containing subunit A1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:T01G9.5(orf name) psi-mi:mel26_caeel(display_long)|uniprotkb:ZK858.4(orf name)|uniprotkb:mel-26(gene name)|psi-mi:mel-26(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458954|imex:IM-11985-330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492257.1|refseq:NP_871793.1|wormbase:T01G9.5a|wormbase:T01G9.5b|ensemblmetazoa:T01G9.5a.1(transcript)|ensemblmetazoa:WBGene00003183(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000785"(chromatin)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051013"(microtubule severing)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0005813"(centrosome)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0090736"(MATH domain binding)|go:"GO:1902120"(negative regulation of meiotic spindle elongation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR028596|interpro:IPR041569|rcsb pdb:5WC0|rcsb pdb:5WC1|rcsb pdb:5WCB|rcsb pdb:6B5D|go:"GO:0005819"(spindle)|rcsb pdb:6UGD|rcsb pdb:6UGE|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|rcsb pdb:6UGF|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008017"(microtubule binding)|go:"GO:0008352"(katanin complex)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|dip:DIP-25343N refseq:NP_492449.2|wormbase:ZK858.4a|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|ensemblmetazoa:WBGene00003209(gene)|ensemblmetazoa:ZK858.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031674"(I band)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-27179N|reactome:R-CEL-5632684 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W8dzUByepgfcMfSsWiLQdK+/pus6239 rogid:LdD7Fd/bItR1N1LukujfPZi0MqI6239 intact-crc:E0B118AA1F447C81|rigid:/u5Bm90PpeviWN8Kz/4UtrdmPd4 false sufficient binding region:3-472("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P51875 uniprotkb:Q95QJ7 intact:EBI-316062|uniprotkb:Q18205|ensemblmetazoa:C26C6.2.1 intact:EBI-316069|uniprotkb:P34408|ensemblmetazoa:F22B7.13.1 psi-mi:gnao_caeel(display_long)|uniprotkb:goa-1(gene name)|psi-mi:goa-1(display_short)|uniprotkb:C26C6.2(orf name) psi-mi:gpr1_caeel(display_long)|uniprotkb:F22B7.13(orf name)|uniprotkb:gpr-1(gene name)|psi-mi:gpr-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458964|imex:IM-11985-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492108.1|wormbase:C26C6.2|ensemblmetazoa:C26C6.2.1(transcript)|ensemblmetazoa:WBGene00001648(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032094"(response to food)|go:"GO:0032223"(negative regulation of synaptic transmission, cholinergic)|go:"GO:0040012"(regulation of locomotion)|go:"GO:0042493"|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045202"(synapse)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051301"(cell division)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|dip:DIP-25342N|reactome:R-CEL-4086398 refseq:NP_498900.1|wormbase:F22B7.13|ensemblmetazoa:F22B7.13.1(transcript)|ensemblmetazoa:WBGene00001688(gene)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005818"(aster)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|dip:DIP-26900N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:44YFS2ve6Go3YZuMGTkit55U4lc6239 rogid:O0UXQO2lBqcHpE5oqnCZ7mojj5g6239 intact-crc:B83AE8C43029EEFB|rigid:qFIP4tDNFp0rNLRsa/z/uOu60MM false - sufficient binding region:346-525("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GT24 uniprotkb:G5ECG0 intact:EBI-323555|uniprotkb:O01903|ensemblmetazoa:F59E12.2.1|ensemblmetazoa:F59E12.2.2 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:zyg1_caeel(display_long)|uniprotkb:zyg-1(gene name)|psi-mi:zyg-1(display_short)|uniprotkb:F59E12.2(orf name)|uniprotkb:Zygote defective protein 1(gene name synonym) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458999|imex:IM-11985-334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495103.1|wormbase:F59E12.2|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0051225"(spindle assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|ensemblmetazoa:F59E12.2.1(transcript)|ensemblmetazoa:F59E12.2.2(transcript)|ensemblmetazoa:WBGene00006988(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0106311"|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1904779"(regulation of protein localization to centrosome)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR040733|interpro:IPR040734|rcsb pdb:4NKB|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-24892N interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bW56U+tOCdP8UXKTudspR9Oi4/Q6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:7ECC7F15E5622AF3|rigid:ElcH1Et0Bq4Vrb+yd17/oOcOq10 false - sufficient binding region:34-260("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:C5VUK2 uniprotkb:Q9N359 intact:EBI-6458987|ensemblmetazoa:Y67H2A.6b.1 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 psi-mi:c5vuk2_caeel(display_long)|uniprotkb:Y67H2A.6(orf name)|uniprotkb:csn-6(gene name)|psi-mi:csn-6(display_short)|uniprotkb:CELE_Y67H2A.6(orf name) psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458984|imex:IM-11985-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000818(gene)|ensemblmetazoa:Y67H2A.6b.1(transcript)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|refseq:NP_001255725.1|wormbase:Y67H2A.6b|interpro:IPR037518 refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Hf0v9RIBG3fVF4QivzWz2C3lwEA6239 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 intact-crc:CE1C805BE82942A4|rigid:ml3cMHn9awc0KXYgm051mdLgAgI false - sufficient binding region:345-412("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XTF3 uniprotkb:O02108 intact:EBI-2005616|uniprotkb:H9G2V8|uniprotkb:H9G2V9|uniprotkb:J7SF89|uniprotkb:Q27GP3|uniprotkb:Q2EEP1|uniprotkb:Q9TVF4|uniprotkb:Q20604|intact:EBI-2476794|ensemblmetazoa:F49E11.1b.1 intact:EBI-329675|ensemblmetazoa:W08F4.8a.1 psi-mi:mbk2_caeel(display_long)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short)|uniprotkb:F49E11.1(orf name)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym) psi-mi:cdc37_caeel(display_long)|uniprotkb:W08F4.8(orf name)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division cycle-related protein 37(gene name synonym)|uniprotkb:cdc-37(gene name)|psi-mi:cdc-37(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6458974|imex:IM-11985-332 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023207.1|refseq:NP_001023208.1|refseq:NP_001040950.1|refseq:NP_001040951.1|refseq:NP_502492.2|wormbase:F49E11.1a|wormbase:F49E11.1b|wormbase:F49E11.1c|wormbase:F49E11.1d|wormbase:F49E11.1e|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|wormbase:F49E11.1f|wormbase:F49E11.1g|wormbase:F49E11.1h|refseq:NP_001255694.1|refseq:NP_001255695.1|refseq:NP_001263802.1|interpro:IPR042521|ensemblmetazoa:F49E11.1b.1(transcript)|ensemblmetazoa:WBGene00003150(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903864"(P granule disassembly) refseq:NP_001040820.1|wormbase:W08F4.8a|reactome:R-CEL-114608|dip:DIP-25193N|ensemblmetazoa:W08F4.8a.1(transcript)|ensemblmetazoa:WBGene00021097(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-CEL-8863795|reactome:R-CEL-9652282|reactome:R-CEL-5675482 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:e0FXCawkUfjiG3D8gHgm4cJMoOU6239 rogid:BGPUAjBwpp1jT1o4miWT7nTRwus6239 intact-crc:EFC531B09B4F0C48|rigid:9r6btZjLTz5klsqn0Ya+HgnKNvc false sufficient binding region:345-495("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:O01488 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-320537|ensemblmetazoa:C13F10.2.1 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:o01488_caeel(display_long)|uniprotkb:kxd-1(gene name)|psi-mi:kxd-1(display_short)|uniprotkb:C13F10.2(orf name)|uniprotkb:CELE_C13F10.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459009|imex:IM-11985-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 refseq:NP_504831.1|wormbase:C13F10.2|ensemblmetazoa:C13F10.2.1(transcript)|ensemblmetazoa:WBGene00015742(gene)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|dip:DIP-27148N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:ZX/rck9tSHblPGJKegKAjZiqxeA6239 intact-crc:3012B26BC6CD76FD|rigid:6MaLMsoL0pUB0E9Jxb/3wwagL5c false sufficient binding region:34-199("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18885 uniprotkb:Q86S66 intact:EBI-326530|ensemblmetazoa:C56C10.8.1|ensemblmetazoa:C56C10.8.2 intact:EBI-326549|uniprotkb:Q9N2Z8|ensemblmetazoa:Y65B4BR.5a.1|ensemblmetazoa:Y65B4BR.5b.1|intact:EBI-679382 psi-mi:btf3_caeel(display_long)|uniprotkb:icd-1(gene name)|psi-mi:icd-1(display_short)|uniprotkb:Inhibitor of cell death 1(gene name synonym)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)|uniprotkb:C56C10.8(orf name) psi-mi:naca_caeel(display_long)|uniprotkb:icd-2(gene name)|psi-mi:icd-2(display_short)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:Inhibitor of cell death 2(gene name synonym)|uniprotkb:Y65B4BR.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459019|imex:IM-11985-336 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495336.1|wormbase:C56C10.8|ensemblmetazoa:WBGene00002045(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|ensemblmetazoa:C56C10.8.1(transcript)|ensemblmetazoa:C56C10.8.2(transcript)|dip:DIP-27302N wormbase:Y65B4BR.5|ensemblmetazoa:WBGene00022042(gene)|ensemblmetazoa:Y65B4BR.5a.1(transcript)|ensemblmetazoa:Y65B4BR.5b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|dip:DIP-25064N|refseq:NP_490749.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2020/08/14 rogid:nGDBS284peDkZE/QpUVU0mOOqRs6239 rogid:8SX3vDiqLUW9gyoLkFPKvxoQZZ46239 intact-crc:764A9457E7D986C0|rigid:rghM5yDBi1rFq8tRDYK3XSu8REs false - sufficient binding region:34-195("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:O62332 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-317758|ensemblmetazoa:R06A4.4a.1 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:o62332_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:R06A4.4(orf name)|uniprotkb:CELE_R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459049|imex:IM-11985-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) refseq:NP_496987.1|wormbase:R06A4.4a|ensemblmetazoa:R06A4.4a.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|dip:DIP-25178N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:vmad0aGDqxNwqAZYykq3lZt5zUs6239 intact-crc:10A1720F2D8DE445|rigid:BwMcVe72WExa1ANdM9/P7D9Onek false - sufficient binding region:340-883("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEM5 uniprotkb:G5ECG0 intact:EBI-320102|ensemblmetazoa:F22B5.7.1 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:zyg9_caeel(display_long)|uniprotkb:zyg-9(gene name)|psi-mi:zyg-9(display_short)|uniprotkb:F22B5.7(orf name) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459039|imex:IM-11985-338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:NP_495784.1|uniprotkb:O61442(uniprot-removed-ac)|rcsb pdb:2OF3|wormbase:F22B5.7|ensemblmetazoa:WBGene00006994(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051231"(spindle elongation)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:F22B5.7.1(transcript)|interpro:IPR034085|interpro:IPR029632 interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:d5IkZ+B1AcKT1ZE2uWfbBzd9p5U6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:9DF11F91F2376FE9|rigid:28ieiq7Jj08fkyvtOwLkNoVhfaE false - sufficient binding region:34-100("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q21295 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-2004307|uniprotkb:Q21296|ensemblmetazoa:K07F5.13a.1 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:q21295_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459029|imex:IM-11985-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) refseq:NP_501772.1|wormbase:K07F5.13a|interpro:IPR024864|interpro:IPR025712|ensemblmetazoa:K07F5.13a.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:CgqZPl+7gsTQJxOMbCCLLuEiUh46239 intact-crc:BE5E9E4D335FB9D0|rigid:mIg9lVIJBF5F0d+eJKv/45f+Nss false sufficient binding region:3-419("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02482 uniprotkb:Q93616 intact:EBI-314716|uniprotkb:P91912|ensemblmetazoa:W02D3.9.1|ensemblmetazoa:W02D3.9.2 intact:EBI-2005589|ensemblmetazoa:F27D4.2a.1 psi-mi:unc37_caeel(display_long)|uniprotkb:unc-37(gene name)|psi-mi:unc-37(display_short)|uniprotkb:esg(gene name synonym)|uniprotkb:W02D3.9(orf name)|uniprotkb:Uncoordinated protein 37(gene name synonym) psi-mi:q93616_caeel(display_long)|uniprotkb:CELE_F27D4.2(orf name)|uniprotkb:F27D4.2(orf name)|uniprotkb:lsy-22(gene name)|psi-mi:lsy-22(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459059|imex:IM-11985-340 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-4641265|refseq:NP_491932.1|wormbase:W02D3.9|reactome:R-CEL-3769402|ensemblmetazoa:W02D3.9.1(transcript)|ensemblmetazoa:W02D3.9.2(transcript)|ensemblmetazoa:WBGene00006773(gene)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008134"(transcription factor binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|dip:DIP-27333N|reactome:R-CEL-201722 refseq:NP_001122461.1|wormbase:F27D4.2a|ensemblmetazoa:F27D4.2a.1(transcript)|ensemblmetazoa:WBGene00009188(gene)|go:"GO:0140297"(DNA-binding transcription factor binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+e4X3QH+GChhuO2oAhaNGVwnO/o6239 rogid:M3oHVB95AOsgyd4wWVgFcOUcics6239 intact-crc:89851DFB51867646|rigid:c0XcxAIm3BhQP/KxHOxzd6iU6Oo false - sufficient binding region:33-99("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:G5EEG9 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-2002698|uniprotkb:Q17326|uniprotkb:Q17358|ensemblmetazoa:M05B5.5a.1 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:hlh2_caeel(display_long)|uniprotkb:hlh-2(gene name)|psi-mi:hlh-2(display_short)|uniprotkb:M05B5.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459069|imex:IM-11985-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) interpro:IPR011598(Helix-loop-helix DNA-binding)|refseq:NP_001021581.1|uniprotkb:Q17588(uniprot-removed-ac)|wormbase:M05B5.5a|interpro:IPR036638|reactome:R-CEL-525793|ensemblmetazoa:M05B5.5a.1(transcript)|ensemblmetazoa:WBGene00001949(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010171"(body morphogenesis)|go:"GO:0014018"(neuroblast fate specification)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0040025"(vulval development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048666"(neuron development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:ufe+4qJHCZh7xXWuoUx81uT1mvU6239 intact-crc:AE816AC492720869|rigid:nczvv8xf7cM/R72vz/W8aNpjW+0 false - sufficient binding region:3-399("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34286 uniprotkb:Q17693 intact:EBI-313778|uniprotkb:Q9BMU3|ensemblmetazoa:C02F5.9.1 intact:EBI-313786|uniprotkb:G8JXY2|ensemblmetazoa:C06A8.1a.1|ensemblmetazoa:C06A8.1a.2 psi-mi:psb1_caeel(display_long)|uniprotkb:pbs-6(gene name)|psi-mi:pbs-6(display_short)|uniprotkb:C02F5.9(orf name)|uniprotkb:Proteasome subunit beta 6(gene name synonym) psi-mi:mthr_caeel(display_long)|uniprotkb:mthf-1(gene name)|psi-mi:mthf-1(display_short)|uniprotkb:C06A8.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459089|imex:IM-11985-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_498806.1|wormbase:C02F5.9|reactome:R-CEL-5632684|ensemblmetazoa:C02F5.9.1(transcript)|ensemblmetazoa:WBGene00003952(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-24619N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_741027.1|wormbase:C06A8.1a|refseq:NP_741028.1|reactome:R-CEL-196757|wormbase:C06A8.1b|ensemblmetazoa:C06A8.1a.1(transcript)|ensemblmetazoa:C06A8.1a.2(transcript)|ensemblmetazoa:WBGene00015512(gene)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0071949"(FAD binding)|go:"GO:0106312"(methylenetetrahydrofolate reductase NADH activity)|go:"GO:0106313"(methylenetetrahydrofolate reductase NADPH activity)|go:"GO:0005829"(cytosol)|interpro:IPR003171(Methylenetetrahydrofolate reductase)|interpro:IPR004621(Eukaryotic-type methylenetetrahydrofolate reductase)|interpro:IPR029041|go:"GO:0004489"("methylenetetrahydrofolate reductase (NAD(P)H) activity")|dip:DIP-26125N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g54+kg5aHsaQMTBH6xZ9h0/20XQ6239 rogid:gENaJ2CAMGFRDcB2JJvEK0GZxiE6239 intact-crc:FAEDBCBF2D0297FB|rigid:sE6QHCXAKebF61J/LPpq5FnBr/w false - sufficient binding region:338-663("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17962 uniprotkb:G5EDD8 intact:EBI-2003707|ensemblmetazoa:C14B1.3.1 intact:EBI-314583|ensemblmetazoa:F46A9.4.1 psi-mi:q17962_caeel(display_long)|uniprotkb:C14B1.3(orf name)|uniprotkb:CELE_C14B1.3(orf name) psi-mi:g5edd8_caeel(display_long)|uniprotkb:skr-2(gene name)|psi-mi:skr-2(display_short)|uniprotkb:CELE_F46A9.4(orf name)|uniprotkb:F46A9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459099|imex:IM-11985-344 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497748.1|wormbase:C14B1.3|interpro:IPR007397(F-box associated region)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR008979(Galactose-binding like)|interpro:IPR039752|interpro:IPR036047|reactome:R-CEL-8951664|reactome:R-CEL-983168|ensemblmetazoa:C14B1.3.1(transcript)|ensemblmetazoa:WBGene00007574(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process) uniprotkb:Q93731(uniprot-removed-ac)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492512.1|wormbase:F46A9.4|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0097602"(cullin family protein binding)|ensemblmetazoa:F46A9.4.1(transcript)|ensemblmetazoa:WBGene00004808(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|interpro:IPR036296 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zqI/cAAbFcJTj/3mjih6SyZZM4E6239 rogid:j2g9jI5SVR7+s5r1E3Pk+j/4lgo6239 intact-crc:2AEC85E2DACF3964|rigid:MXEoy8qG31IdfMQ2iSJ6aCsPy0k false sufficient binding region:3-384("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93714 uniprotkb:Q20049 intact:EBI-316891|ensemblmetazoa:F43G9.1.1|ensemblmetazoa:F43G9.1.2 intact:EBI-2003412|ensemblmetazoa:F35G12.2.1|ensemblmetazoa:F35G12.2.2|ensemblmetazoa:F35G12.2.3 psi-mi:idh3a_caeel(display_long)|uniprotkb:idha-1(gene name)|psi-mi:idha-1(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:F43G9.1(orf name) psi-mi:q20049_caeel(display_long)|uniprotkb:idhg-1(gene name)|psi-mi:idhg-1(display_short)|uniprotkb:F35G12.2(orf name)|uniprotkb:CELE_F35G12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459079|imex:IM-11985-342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492330.2|wormbase:F43G9.1|interpro:IPR019818|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR024084|reactome:R-CEL-71403|ensemblmetazoa:F43G9.1.1(transcript)|ensemblmetazoa:F43G9.1.2(transcript)|ensemblmetazoa:WBGene00009664(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding) refseq:NP_497927.2|wormbase:F35G12.2|interpro:IPR019818|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR024084|reactome:R-CEL-71403|ensemblmetazoa:F35G12.2.1(transcript)|ensemblmetazoa:F35G12.2.2(transcript)|ensemblmetazoa:F35G12.2.3(transcript)|ensemblmetazoa:WBGene00009440(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:NVCdhmlo8ofGGIyNs1OoP6jUBHM6239 rogid:8VEtHw9s/bKjQdPY2lc8vEEid7E6239 intact-crc:AA0EE5338D06546E|rigid:YersqqCzxdaUjK4IAeIZvOBuOQM false - sufficient binding region:3-396("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10984 uniprotkb:P10986 intact:EBI-316166|uniprotkb:O45744|ensemblmetazoa:T04C12.5.1|ensemblmetazoa:T04C12.5.2|ensemblmetazoa:T04C12.5.3 intact:EBI-321916|uniprotkb:Q7YSY2|ensemblmetazoa:M03F4.2a.1 psi-mi:act2_caeel(display_long)|uniprotkb:act-2(gene name)|psi-mi:act-2(display_short)|uniprotkb:T04C12.5(orf name) psi-mi:act4_caeel(display_long)|uniprotkb:act-4(gene name)|psi-mi:act-4(display_short)|uniprotkb:M03F4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459109|imex:IM-11985-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505818.1|wormbase:T04C12.5|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|ensemblmetazoa:T04C12.5.1(transcript)|ensemblmetazoa:T04C12.5.2(transcript)|ensemblmetazoa:T04C12.5.3(transcript)|ensemblmetazoa:WBGene00000064(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040011"(locomotion)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-25116N refseq:NP_508841.1|wormbase:M03F4.2a|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|ensemblmetazoa:M03F4.2a.1(transcript)|ensemblmetazoa:WBGene00000066(gene)|go:"GO:0000281"(mitotic cytokinesis)|dip:DIP-27204N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pqXk6IfTnhM0CgPVRlu+EK57pDs6239 rogid:zehthX6Qo/gSO5k1j5Epcffr8Sc6239 intact-crc:67697C2CAAD6DAB1|rigid:NE8eOf3plKrJTb1/qlCUYQrg3Y8 false sufficient binding region:3-376("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10984 uniprotkb:P10986 intact:EBI-316166|uniprotkb:O45744|ensemblmetazoa:T04C12.5.1|ensemblmetazoa:T04C12.5.2|ensemblmetazoa:T04C12.5.3 intact:EBI-321916|uniprotkb:Q7YSY2|ensemblmetazoa:M03F4.2a.1 psi-mi:act2_caeel(display_long)|uniprotkb:act-2(gene name)|psi-mi:act-2(display_short)|uniprotkb:T04C12.5(orf name) psi-mi:act4_caeel(display_long)|uniprotkb:act-4(gene name)|psi-mi:act-4(display_short)|uniprotkb:M03F4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459119|imex:IM-11985-346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505818.1|wormbase:T04C12.5|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|ensemblmetazoa:T04C12.5.1(transcript)|ensemblmetazoa:T04C12.5.2(transcript)|ensemblmetazoa:T04C12.5.3(transcript)|ensemblmetazoa:WBGene00000064(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040011"(locomotion)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-25116N refseq:NP_508841.1|wormbase:M03F4.2a|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|ensemblmetazoa:M03F4.2a.1(transcript)|ensemblmetazoa:WBGene00000066(gene)|go:"GO:0000281"(mitotic cytokinesis)|dip:DIP-27204N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pqXk6IfTnhM0CgPVRlu+EK57pDs6239 rogid:zehthX6Qo/gSO5k1j5Epcffr8Sc6239 intact-crc:F8C046043CEF1462|rigid:NE8eOf3plKrJTb1/qlCUYQrg3Y8 false - sufficient binding region:3-376("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10984 uniprotkb:P10984 intact:EBI-316166|uniprotkb:O45744|ensemblmetazoa:T04C12.5.1|ensemblmetazoa:T04C12.5.2|ensemblmetazoa:T04C12.5.3 intact:EBI-316166|uniprotkb:O45744|ensemblmetazoa:T04C12.5.1|ensemblmetazoa:T04C12.5.2|ensemblmetazoa:T04C12.5.3 psi-mi:act2_caeel(display_long)|uniprotkb:act-2(gene name)|psi-mi:act-2(display_short)|uniprotkb:T04C12.5(orf name) psi-mi:act2_caeel(display_long)|uniprotkb:act-2(gene name)|psi-mi:act-2(display_short)|uniprotkb:T04C12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459129|imex:IM-11985-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505818.1|wormbase:T04C12.5|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|ensemblmetazoa:T04C12.5.1(transcript)|ensemblmetazoa:T04C12.5.2(transcript)|ensemblmetazoa:T04C12.5.3(transcript)|ensemblmetazoa:WBGene00000064(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040011"(locomotion)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-25116N refseq:NP_505818.1|wormbase:T04C12.5|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|ensemblmetazoa:T04C12.5.1(transcript)|ensemblmetazoa:T04C12.5.2(transcript)|ensemblmetazoa:T04C12.5.3(transcript)|ensemblmetazoa:WBGene00000064(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040011"(locomotion)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-25116N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pqXk6IfTnhM0CgPVRlu+EK57pDs6239 rogid:pqXk6IfTnhM0CgPVRlu+EK57pDs6239 intact-crc:9A20FFFABFAE64DD|rigid:xC/t11GV4e/2fX18dKTxfukh+iU false - sufficient binding region:3-376("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32744 uniprotkb:O45815 intact:EBI-1000652|ensemblmetazoa:R107.6a.1|ensemblmetazoa:R107.6a.2 intact:EBI-314481|ensemblmetazoa:T25C8.2.1|ensemblmetazoa:T25C8.2.2|ensemblmetazoa:T25C8.2.3 psi-mi:clas2_caeel(display_long)|uniprotkb:cls-2(gene name)|psi-mi:cls-2(display_short)|uniprotkb:R107.6(orf name) psi-mi:o45815_caeel(display_long)|uniprotkb:act-5(gene name)|psi-mi:act-5(display_short)|uniprotkb:CELE_T25C8.2(orf name)|uniprotkb:T25C8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459139|imex:IM-11985-348 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499005.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|ensemblmetazoa:R107.6a.1(transcript)|ensemblmetazoa:R107.6a.2(transcript)|ensemblmetazoa:WBGene00000549(gene)|go:"GO:0000212"(meiotic spindle organization)|interpro:IPR024395|go:"GO:0051316"(attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0099636"(cytoplasmic streaming)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045180"(basal cortex)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051306"(mitotic sister chromatid separation)|interpro:IPR034085|wormbase:R107.6a refseq:NP_499809.1|wormbase:T25C8.2|ensemblmetazoa:T25C8.2.1(transcript)|ensemblmetazoa:T25C8.2.2(transcript)|ensemblmetazoa:T25C8.2.3(transcript)|ensemblmetazoa:WBGene00000067(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0035148"(tube formation)|go:"GO:0097516"(microvillar actin bundle)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:1990357"(terminal web)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-24432N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zm5gUC9V57hmHtyjma+R2MN6LSM6239 rogid:sH4WCAz2hAFWd90um5at7FhG98Y6239 intact-crc:9653DC5A3B1D491E|rigid:ibXw2WgsSazL0k5MekObxq4uRfs false - sufficient binding region:3-375("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10983 uniprotkb:O45815 intact:EBI-312653|uniprotkb:P10985 intact:EBI-314481|ensemblmetazoa:T25C8.2.1|ensemblmetazoa:T25C8.2.2|ensemblmetazoa:T25C8.2.3 psi-mi:act1_caeel(display_long)|uniprotkb:act-1(gene name)|psi-mi:act-1(display_short)|uniprotkb:T04C12.4(orf name)|uniprotkb:act-3(gene name)|psi-mi:act-3(display_short)|uniprotkb:T04C12.6(orf name) psi-mi:o45815_caeel(display_long)|uniprotkb:act-5(gene name)|psi-mi:act-5(display_short)|uniprotkb:CELE_T25C8.2(orf name)|uniprotkb:T25C8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459149|imex:IM-11985-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005524"(ATP binding)|go:"GO:0007517"(muscle organ development)|refseq:NP_505817.1|refseq:NP_505819.1|wormbase:T04C12.4|wormbase:T04C12.6|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|rcsb pdb:1D4X|go:"GO:0009790"(embryo development)|go:"GO:0030036"(actin cytoskeleton organization) refseq:NP_499809.1|wormbase:T25C8.2|ensemblmetazoa:T25C8.2.1(transcript)|ensemblmetazoa:T25C8.2.2(transcript)|ensemblmetazoa:T25C8.2.3(transcript)|ensemblmetazoa:WBGene00000067(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030536"(larval feeding behavior)|go:"GO:0035148"(tube formation)|go:"GO:0097516"(microvillar actin bundle)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:1990357"(terminal web)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-24432N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:FfocOk3zTuKPi2M4G/gWUnYn5Dc6239 rogid:sH4WCAz2hAFWd90um5at7FhG98Y6239 intact-crc:714C607A2DE3DEFF|rigid:bPfXrG2UYJ1AUw6AIpz4Y37jwxE false - sufficient binding region:3-375("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10664 uniprotkb:Q07292 intact:EBI-322144|ensemblmetazoa:Y54E10BL.6.1 intact:EBI-314941|uniprotkb:Q6RT23|uniprotkb:Q8MXT8|uniprotkb:Q9N4E3|ensemblmetazoa:Y73B6A.5a.1|ensemblmetazoa:Y73B6A.5b.1 psi-mi:mek2_caeel(display_long)|uniprotkb:mek-2(gene name)|psi-mi:mek-2(display_short)|uniprotkb:Y54E10BL.6(orf name) psi-mi:kraf1_caeel(display_long)|uniprotkb:lin-45(gene name)|psi-mi:lin-45(display_short)|uniprotkb:raf-1(gene name synonym)|uniprotkb:Y73B6A.5(orf name)|uniprotkb:Abnormal cell lineage protein 45(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459159|imex:IM-11985-350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-170968|refseq:NP_491087.1|wormbase:Y54E10BL.6|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0040025"(vulval development)|go:"GO:0048477"(oogenesis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|ensemblmetazoa:WBGene00003186(gene)|ensemblmetazoa:Y54E10BL.6.1(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|reactome:R-CEL-110056|reactome:R-CEL-112411|reactome:R-CEL-445144|reactome:R-CEL-5674135|reactome:R-CEL-5674499 refseq:NP_741430.3|wormbase:Y73B6A.5a|wormbase:Y73B6A.5b|interpro:IPR011009(Protein kinase-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblmetazoa:WBGene00003030(gene)|reactome:R-CEL-170968|reactome:R-CEL-5673000|reactome:R-CEL-5675482|reactome:R-CEL-392517|reactome:R-CEL-430116|reactome:R-CEL-5621575|reactome:R-CEL-5674135|reactome:R-CEL-5674499|reactome:R-CEL-5675221|ensemblmetazoa:WBGene00003030(gene)|ensemblmetazoa:WBGene00003030(gene)|ensemblmetazoa:Y73B6A.5a.1(transcript)|ensemblmetazoa:Y73B6A.5b.1(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0040025"(vulval development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR029071|reactome:R-CEL-2672351|refseq:NP_001293844.1|refseq:NP_741431.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aTrjvklEoaA8kIbZWB/Iy20tsBs6239 rogid:kcfAZSx3vZ9jFRUwoGt8m7cv7wI6239 intact-crc:D2D029426B481912|rigid:1bton5zOq6aoea7odNYKhUt2CRU false - sufficient binding region:336-797("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01683 uniprotkb:O62333 intact:EBI-2004633|ensemblmetazoa:C32F10.5.1 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 psi-mi:ssp1b_caeel(display_long)|uniprotkb:hmg-3(gene name)|psi-mi:hmg-3(display_short)|uniprotkb:Facilitates chromatin transcription complex subunit ssrp1-B(gene name synonym)|uniprotkb:Structure-specific recognition protein 1-B(gene name synonym)|uniprotkb:HMG box-containing protein 3(gene name synonym)|uniprotkb:C32F10.5(orf name) psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459189|imex:IM-11985-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491688.1|wormbase:C32F10.5|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR035417|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR038167|interpro:IPR036910|ensemblmetazoa:C32F10.5.1(transcript)|ensemblmetazoa:WBGene00001973(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0060465"(pharynx development)|go:"GO:1902275"(regulation of chromatin organization) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Gi9geFlGiSWKdPaIiOub2sSz30A6239 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 intact-crc:480C06FC4ED4C4C5|rigid:5bB8DPIHT31DOraKmnFD1tehjBQ false sufficient binding region:336-470("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94420 uniprotkb:Q09345 intact:EBI-320790|uniprotkb:Q94139|ensemblmetazoa:ZK858.4a.1 intact:EBI-2006279|ensemblmetazoa:R144.2a.1|ensemblmetazoa:R144.2a.2 psi-mi:mel26_caeel(display_long)|uniprotkb:ZK858.4(orf name)|uniprotkb:mel-26(gene name)|psi-mi:mel-26(display_short) psi-mi:pcf11_caeel(display_long)|uniprotkb:R144.2(orf name)|uniprotkb:pcf-11(gene name)|psi-mi:pcf-11(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459179|imex:IM-11985-352 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492449.2|wormbase:ZK858.4a|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|ensemblmetazoa:WBGene00003209(gene)|ensemblmetazoa:ZK858.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031674"(I band)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-27179N|reactome:R-CEL-5632684 refseq:NP_498068.1|wormbase:R144.2a|interpro:IPR008942(ENTH/VHS)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|reactome:R-CEL-6807505|reactome:R-CEL-73856|ensemblmetazoa:R144.2a.1(transcript)|ensemblmetazoa:R144.2a.2(transcript)|ensemblmetazoa:WBGene00020092(gene)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LdD7Fd/bItR1N1LukujfPZi0MqI6239 rogid:XTyRR+k9dN5uoxwUXnAuM34SSUA6239 intact-crc:6A8087CC50B4CEDB|rigid:MBxC1ChFQx+aS4hPmPt8LrNAxPo false - sufficient binding region:336-537("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46563 uniprotkb:P46563 intact:EBI-314454|ensemblmetazoa:F01F1.12a.1|ensemblmetazoa:F01F1.12a.2 intact:EBI-314454|ensemblmetazoa:F01F1.12a.1|ensemblmetazoa:F01F1.12a.2 psi-mi:alf2_caeel(display_long)|uniprotkb:F01F1.12(orf name)|uniprotkb:Aldolase CE-2(gene name synonym)|uniprotkb:aldo-2(gene name)|psi-mi:aldo-2(display_short) psi-mi:alf2_caeel(display_long)|uniprotkb:F01F1.12(orf name)|uniprotkb:Aldolase CE-2(gene name synonym)|uniprotkb:aldo-2(gene name)|psi-mi:aldo-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459169|imex:IM-11985-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021240.1|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|go:"GO:0006096"(glycolytic process)|ensemblmetazoa:F01F1.12a.1(transcript)|ensemblmetazoa:F01F1.12a.2(transcript)|ensemblmetazoa:WBGene00017166(gene)|go:"GO:0000792"(heterochromatin)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|reactome:R-CEL-70263|reactome:R-CEL-6798695|dip:DIP-24398N|reactome:R-CEL-70171|reactome:R-CEL-114608|wormbase:F01F1.12 refseq:NP_001021240.1|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|go:"GO:0006096"(glycolytic process)|ensemblmetazoa:F01F1.12a.1(transcript)|ensemblmetazoa:F01F1.12a.2(transcript)|ensemblmetazoa:WBGene00017166(gene)|go:"GO:0000792"(heterochromatin)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|reactome:R-CEL-70263|reactome:R-CEL-6798695|dip:DIP-24398N|reactome:R-CEL-70171|reactome:R-CEL-114608|wormbase:F01F1.12 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:E0PrOlgxA2uHJmPnijqKfj8HhUA6239 rogid:E0PrOlgxA2uHJmPnijqKfj8HhUA6239 intact-crc:59EA91018DC08971|rigid:KUpuAFJA9tRmYevoo1OPLTb+FBw false sufficient binding region:3-366("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P13508 uniprotkb:P90868 intact:EBI-319522|ensemblmetazoa:F02A9.6.1 intact:EBI-317074|ensemblmetazoa:F39H11.5.1 psi-mi:glp1_caeel(display_long)|uniprotkb:glp-1(gene name)|psi-mi:glp-1(display_short)|uniprotkb:emb-33(gene name synonym)|uniprotkb:F02A9.6(orf name) psi-mi:p90868_caeel(display_long)|uniprotkb:pbs-7(gene name)|psi-mi:pbs-7(display_short)|uniprotkb:F39H11.5(orf name)|uniprotkb:CELE_F39H11.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459209|imex:IM-11985-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499014.1|wormbase:F02A9.6|ensemblmetazoa:F02A9.6.1(transcript)|ensemblmetazoa:WBGene00001609(gene)|go:"GO:0001708"(cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0003713"(transcription coactivator activity)|interpro:IPR001881(EGF-like calcium-binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|interpro:IPR002110(Ankyrin)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|go:"GO:0005886"(plasma membrane)|interpro:IPR018097|interpro:IPR020683|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0012505"(endomembrane system)|interpro:IPR035993|interpro:IPR036770|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0043055"(maintenance of dauer)|go:"GO:0043282"(pharyngeal muscle development)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|dip:DIP-26562N reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_492354.1|wormbase:F39H11.5|ensemblmetazoa:F39H11.5.1(transcript)|ensemblmetazoa:WBGene00003953(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR029055|reactome:R-CEL-5632684|reactome:R-CEL-8932339|dip:DIP-26967N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gJCULzDV99yj+GQn/Hel9r2t+lw6239 rogid:b0ur9kPZL37Eqp8qt6e41061Zc06239 intact-crc:95D4FCC9FB9CE43A|rigid:D5lqJggdpHe5xszV6OTFtWWNdcM false sufficient binding region:336-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:O62333 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459199|imex:IM-11985-354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 intact-crc:5FE051CDFEFCC2F2|rigid:gLuQ85CEpD/qLMiWhVCSWOBpaZ0 false sufficient binding region:336-470("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:Q17796 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459239|imex:IM-11985-358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 intact-crc:7177005C014E41F1|rigid:1DzeC6AQpz+lW+0o/9h1MoR/Idc false - sufficient binding region:335-537("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17796 uniprotkb:O76258 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 intact:EBI-2002148|ensemblmetazoa:C09G12.9.1 psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:o76258_caeel(display_long)|uniprotkb:tsg-101(gene name)|psi-mi:tsg-101(display_short)|uniprotkb:CELE_C09G12.9(orf name)|uniprotkb:C09G12.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459219|imex:IM-11985-356 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019 refseq:NP_500364.2|wormbase:C09G12.9|interpro:IPR017916|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR008883(Tumour susceptibility gene 101)|reactome:R-CEL-917729|interpro:IPR037202|ensemblmetazoa:C09G12.9.1(transcript)|ensemblmetazoa:WBGene00015658(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 rogid:tAhzbKmVoJZA+IwR6RLdGgDFIYI6239 intact-crc:B939C21EB0D4ECB3|rigid:dUqZsgWWc2ofXBs3RBqO+RP0xWU false sufficient binding region:335-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q17796 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459229|imex:IM-11985-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 intact-crc:EE667C591B92E3E9|rigid:2v5mQzS9KQD8VPWTPNHBm0FGq8M false - sufficient binding region:335-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01576 uniprotkb:P34331-2 intact:EBI-318147|ensemblmetazoa:F53F10.5.1|ensemblmetazoa:F53F10.5.2 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 psi-mi:o01576_caeel(display_long)|uniprotkb:npp-11(gene name)|psi-mi:npp-11(display_short)|uniprotkb:F53F10.5(orf name)|uniprotkb:CELE_F53F10.5(orf name) psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459249|imex:IM-11985-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F53F10.5|refseq:NP_491232.1|ensemblmetazoa:F53F10.5.1(transcript)|ensemblmetazoa:F53F10.5.2(transcript)|ensemblmetazoa:WBGene00003797(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25053N intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:MI7h0vaxVjYQ8SIw1bMVdk5rCl06239 rogid:u830S0jdkV753ilx7DbxmhPocv86239 intact-crc:B341E9677CD6764C|rigid:OD2UjytOUYlxF8bsOUp01zCb4eo false sufficient binding region:334-805("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N359 uniprotkb:O01576 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 intact:EBI-318147|ensemblmetazoa:F53F10.5.1|ensemblmetazoa:F53F10.5.2 psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:o01576_caeel(display_long)|uniprotkb:npp-11(gene name)|psi-mi:npp-11(display_short)|uniprotkb:F53F10.5(orf name)|uniprotkb:CELE_F53F10.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459259|imex:IM-11985-360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 wormbase:F53F10.5|refseq:NP_491232.1|ensemblmetazoa:F53F10.5.1(transcript)|ensemblmetazoa:F53F10.5.2(transcript)|ensemblmetazoa:WBGene00003797(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25053N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 rogid:MI7h0vaxVjYQ8SIw1bMVdk5rCl06239 intact-crc:39DDE475FC1DB000|rigid:1mErYIyndb+qDfImE1R1kTdKzfA false - sufficient binding region:334-805("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDX9 uniprotkb:G5EDD8 intact:EBI-2003730|ensemblmetazoa:F08A8.7.1|ensemblmetazoa:F08A8.7.2 intact:EBI-314583|ensemblmetazoa:F46A9.4.1 psi-mi:g5edx9_caeel(display_long)|uniprotkb:fbxa-101(gene name)|psi-mi:fbxa-101(display_short)|uniprotkb:CELE_F08A8.7(orf name)|uniprotkb:F08A8.7(orf name) psi-mi:g5edd8_caeel(display_long)|uniprotkb:skr-2(gene name)|psi-mi:skr-2(display_short)|uniprotkb:CELE_F46A9.4(orf name)|uniprotkb:F46A9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459269|imex:IM-11985-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002900(Protein of unknown function DUF38, Caenorhabditis species)|refseq:NP_493266.1|uniprotkb:Q9N6F2(uniprot-removed-ac)|interpro:IPR040161|wormbase:F08A8.7|ensemblmetazoa:F08A8.7.1(transcript)|ensemblmetazoa:F08A8.7.2(transcript)|ensemblmetazoa:WBGene00008569(gene) uniprotkb:Q93731(uniprot-removed-ac)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492512.1|wormbase:F46A9.4|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0097602"(cullin family protein binding)|ensemblmetazoa:F46A9.4.1(transcript)|ensemblmetazoa:WBGene00004808(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|interpro:IPR036296 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:FdIkswj1q6DyU+EpLCu8lerNp0A6239 rogid:j2g9jI5SVR7+s5r1E3Pk+j/4lgo6239 intact-crc:CFB6EE39BF908103|rigid:3dTrqe/GFFKALNADx9TGMG/Cwtg false sufficient binding region:3-342("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4A7-1 uniprotkb:P34643 intact:EBI-6456140|ensemblmetazoa:Y77E11A.13a.1 intact:EBI-324902|uniprotkb:M1ZK05|ensemblmetazoa:ZK512.5a.1 psi-mi:q9n4a7-1(display_long)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:Nuclear pore complex protein 20(gene name synonym)|uniprotkb:npp-20(gene name)|psi-mi:npp-20(display_short)|uniprotkb:CeSec13R(gene name synonym)|uniprotkb:sec-13(gene name synonym)|uniprotkb:Y77E11A.13(orf name) psi-mi:sc161_caeel(display_long)|uniprotkb:sec-16A.1(gene name)|psi-mi:sec-16A.1(display_short)|uniprotkb:Secretory cargo traffic protein sec-16A.1(gene name synonym)|uniprotkb:sec-16(gene name synonym)|uniprotkb:ZK512.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459279|imex:IM-11985-362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318290(isoform-parent)|ensemblmetazoa:WBGene00003806(gene)|ensemblmetazoa:Y77E11A.13a.1(transcript) refseq:NP_499022.1|wormbase:ZK512.5a|wormbase:ZK512.5b|ensemblmetazoa:WBGene00013985(gene)|ensemblmetazoa:ZK512.5a.1(transcript)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|refseq:NP_001293651.1|dip:DIP-25929N|reactome:R-CEL-204005 psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZKmmnaa7DFkQzBBKNad56Ic7GvI6239 rogid:MNubI0LLX2Ewt6rjY5w88MQajIo6239 intact-crc:29C6CB46A0189AB8|rigid:dXEMld+Xsw3oa0PN/1DSZ3fCqKg false - sufficient binding region:333-468("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XW79 uniprotkb:Q09248 intact:EBI-331742|uniprotkb:Q966Q4|ensemblmetazoa:Y75B8A.30.1 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 psi-mi:pp4c1_caeel(display_long)|uniprotkb:pph-4.1(gene name)|psi-mi:pph-4.1(display_short)|uniprotkb:Y75B8A.30(orf name) psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459309|imex:IM-11985-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499603.1|wormbase:Y75B8A.30|dip:DIP-24807N|ensemblmetazoa:WBGene00004085(gene)|ensemblmetazoa:Y75B8A.30.1(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016311"(dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1905261"(regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052 refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:2W4T4LTMeuxTZrZu2Y2gg7bUAXE6239 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 intact-crc:E0E163B579BE1503|rigid:rZ0j11qVpOPyi+uGHJlBf2kebzo false - sufficient binding region:33-298("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XW79 uniprotkb:Q9N4E9 intact:EBI-331742|uniprotkb:Q966Q4|ensemblmetazoa:Y75B8A.30.1 intact:EBI-331766|ensemblmetazoa:Y71H2B.3.1 psi-mi:pp4c1_caeel(display_long)|uniprotkb:pph-4.1(gene name)|psi-mi:pph-4.1(display_short)|uniprotkb:Y75B8A.30(orf name) psi-mi:pp4rs_caeel(display_long)|uniprotkb:ppfr-4(gene name)|psi-mi:ppfr-4(display_short)|uniprotkb:Y71H2B.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459289|imex:IM-11985-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499603.1|wormbase:Y75B8A.30|dip:DIP-24807N|ensemblmetazoa:WBGene00004085(gene)|ensemblmetazoa:Y75B8A.30.1(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016311"(dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1905261"(regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052 refseq:NP_497591.1|wormbase:Y71H2B.3|dip:DIP-27072N|ensemblmetazoa:WBGene00022193(gene)|ensemblmetazoa:Y71H2B.3.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:2W4T4LTMeuxTZrZu2Y2gg7bUAXE6239 rogid:DmlEnJ9TsnA4eRRlzusNPoTeDy46239 intact-crc:39D74B26CC2D0E0F|rigid:ZOY20JZO6twew3qL273PZ4UwG30 false sufficient binding region:3-333("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q09248 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459299|imex:IM-11985-364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 intact-crc:2CBD60C8541B4438|rigid:4NRrb8/NzKnRgcapLuX7S8n1Vwc false - sufficient binding region:33-298("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:Q8MXR2 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-327674|ensemblmetazoa:Y73B6BL.33a.1 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q8mxr2_caeel(display_long)|uniprotkb:hrpf-2(gene name)|psi-mi:hrpf-2(display_short)|uniprotkb:CELE_Y73B6BL.33(orf name)|uniprotkb:Y73B6BL.33(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459329|imex:IM-11985-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 refseq:NP_741422.1|wormbase:Y73B6BL.33a|ensemblmetazoa:WBGene00022253(gene)|ensemblmetazoa:Y73B6BL.33a.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|dip:DIP-24945N|reactome:R-CEL-72163 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:vstHX9nskJYcL8v9uG44qxSW+8Q6239 intact-crc:9D2DC3BDF9987B6D|rigid:rat0sU9amQkjSNNHVEe+U4wbi0o false - sufficient binding region:331-610("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NAN2-1 uniprotkb:Q09248 intact:EBI-6458686|ensemblmetazoa:T26E3.3a.1|ensemblmetazoa:T26E3.3a.2 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 psi-mi:q9nan2-1(display_long)|uniprotkb:T26E3.3(orf name)|uniprotkb:par-6(gene name)|psi-mi:par-6(display_short) psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459319|imex:IM-11985-366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318782(isoform-parent)|ensemblmetazoa:T26E3.3a.1(transcript)|ensemblmetazoa:T26E3.3a.2(transcript)|ensemblmetazoa:WBGene00003921(gene) refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CWjdm5DAUzsqFaqTydp1Q/EJobU6239 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 intact-crc:763778D260614A1F|rigid:QztyUnhJ29J14knK/TXvUkHjwBM false - sufficient binding region:33-227("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02115 uniprotkb:O02115 intact:EBI-318162|ensemblmetazoa:W03D2.4.1 intact:EBI-318162|ensemblmetazoa:W03D2.4.1 psi-mi:pcna_caeel(display_long)|uniprotkb:pcn-1(gene name)|psi-mi:pcn-1(display_short)|uniprotkb:W03D2.4(orf name) psi-mi:pcna_caeel(display_long)|uniprotkb:pcn-1(gene name)|psi-mi:pcn-1(display_short)|uniprotkb:W03D2.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459339|imex:IM-11985-368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-110320|reactome:R-CEL-5358565|reactome:R-CEL-69091|reactome:R-CEL-69166|reactome:R-CEL-69183|reactome:R-CEL-6782135|reactome:R-CEL-6782210|wormbase:W03D2.4|refseq:NP_500466.3|reactome:R-CEL-4615885|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0043626"(PCNA complex)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|ensemblmetazoa:W03D2.4.1(transcript)|ensemblmetazoa:WBGene00003955(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006298"(mismatch repair)|dip:DIP-25347N|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397 reactome:R-CEL-110320|reactome:R-CEL-5358565|reactome:R-CEL-69091|reactome:R-CEL-69166|reactome:R-CEL-69183|reactome:R-CEL-6782135|reactome:R-CEL-6782210|wormbase:W03D2.4|refseq:NP_500466.3|reactome:R-CEL-4615885|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0043626"(PCNA complex)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|ensemblmetazoa:W03D2.4.1(transcript)|ensemblmetazoa:WBGene00003955(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006298"(mismatch repair)|dip:DIP-25347N|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Cqxj2E3ydeiDGIeNlyNoUjJH3lM6239 rogid:Cqxj2E3ydeiDGIeNlyNoUjJH3lM6239 intact-crc:547BC6C01AC6AFDF|rigid:R5Kfty6P4KTt9JvogOdG87Wo+mA false - sufficient binding region:3-263("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93831 uniprotkb:Q95QC4 intact:EBI-315800|ensemblmetazoa:F59C6.5.1 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 psi-mi:q93831_caeel(display_long)|uniprotkb:F59C6.5(orf name)|uniprotkb:CELE_F59C6.5(orf name) psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459359|imex:IM-11985-370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492752.1|wormbase:F59C6.5|ensemblmetazoa:F59C6.5.1(transcript)|ensemblmetazoa:WBGene00010326(gene)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|interpro:IPR019377|interpro:IPR039993|dip:DIP-25326N|reactome:R-CEL-6799198 refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XDFcNzOUcFsl49rARSorLWZkruU6239 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 intact-crc:0CCACA7A5A44FAD4|rigid:gLkPkbCd4Rd3j48HoKw3LI/FAsE false sufficient binding region:3-260("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34286 uniprotkb:Q93831 intact:EBI-313778|uniprotkb:Q9BMU3|ensemblmetazoa:C02F5.9.1 intact:EBI-315800|ensemblmetazoa:F59C6.5.1 psi-mi:psb1_caeel(display_long)|uniprotkb:pbs-6(gene name)|psi-mi:pbs-6(display_short)|uniprotkb:C02F5.9(orf name)|uniprotkb:Proteasome subunit beta 6(gene name synonym) psi-mi:q93831_caeel(display_long)|uniprotkb:F59C6.5(orf name)|uniprotkb:CELE_F59C6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459349|imex:IM-11985-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_498806.1|wormbase:C02F5.9|reactome:R-CEL-5632684|ensemblmetazoa:C02F5.9.1(transcript)|ensemblmetazoa:WBGene00003952(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-24619N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_492752.1|wormbase:F59C6.5|ensemblmetazoa:F59C6.5.1(transcript)|ensemblmetazoa:WBGene00010326(gene)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|interpro:IPR019377|interpro:IPR039993|dip:DIP-25326N|reactome:R-CEL-6799198 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g54+kg5aHsaQMTBH6xZ9h0/20XQ6239 rogid:XDFcNzOUcFsl49rARSorLWZkruU6239 intact-crc:1C2E104EB4AA79B2|rigid:F1dPWkftHdBEzp8IyJLMoqr4UsQ false - sufficient binding region:3-260("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21295 uniprotkb:O62332 intact:EBI-2004307|uniprotkb:Q21296|ensemblmetazoa:K07F5.13a.1 intact:EBI-317758|ensemblmetazoa:R06A4.4a.1 psi-mi:q21295_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:o62332_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:R06A4.4(orf name)|uniprotkb:CELE_R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459379|imex:IM-11985-372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501772.1|wormbase:K07F5.13a|interpro:IPR024864|interpro:IPR025712|ensemblmetazoa:K07F5.13a.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) refseq:NP_496987.1|wormbase:R06A4.4a|ensemblmetazoa:R06A4.4a.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|dip:DIP-25178N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CgqZPl+7gsTQJxOMbCCLLuEiUh46239 rogid:vmad0aGDqxNwqAZYykq3lZt5zUs6239 intact-crc:D45C646FEB090C45|rigid:sQe/+IEJxQ8o9fxbdLr3Jik1YxY false - sufficient binding region:325-883("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4E9 uniprotkb:G5EGK8 intact:EBI-331766|ensemblmetazoa:Y71H2B.3.1 intact:EBI-319655|ensemblmetazoa:F38H4.9.1|ensemblmetazoa:F38H4.9.2|ensemblmetazoa:F38H4.9.3 psi-mi:pp4rs_caeel(display_long)|uniprotkb:ppfr-4(gene name)|psi-mi:ppfr-4(display_short)|uniprotkb:Y71H2B.3(orf name) psi-mi:pp2a_caeel(display_long)|uniprotkb:let-92(gene name)|psi-mi:let-92(display_short)|uniprotkb:F38H4.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459369|imex:IM-11985-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497591.1|wormbase:Y71H2B.3|dip:DIP-27072N|ensemblmetazoa:WBGene00022193(gene)|ensemblmetazoa:Y71H2B.3.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511 uniprotkb:Q27498(uniprot-removed-ac)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_502247.1|ensemblmetazoa:F38H4.9.1(transcript)|ensemblmetazoa:F38H4.9.2(transcript)|ensemblmetazoa:F38H4.9.3(transcript)|ensemblmetazoa:WBGene00002363(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0018985"(pronuclear envelope synthesis)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046872"(metal ion binding)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0106306"|go:"GO:0106307"|wormbase:F38H4.9|reactome:R-CEL-389513|reactome:R-CEL-6811558|interpro:IPR029052|reactome:R-CEL-5673000|reactome:R-CEL-5675221|reactome:R-CEL-69231|reactome:R-CEL-195253|reactome:R-CEL-198753|reactome:R-CEL-202670|reactome:R-CEL-2995383|reactome:R-CEL-69273|reactome:R-CEL-196299|reactome:R-CEL-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:DmlEnJ9TsnA4eRRlzusNPoTeDy46239 rogid:d5e/T74YELePZOaa8rUlLe8oWw86239 intact-crc:A73550DBB56A3712|rigid:OOgGgwYvlH4XPXjfoKz56AV3c1s false - sufficient binding region:3-259("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:Q18508 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-2002730|ensemblmetazoa:C38D4.3.1 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:mel28_caeel(display_long)|uniprotkb:mel-28(gene name)|psi-mi:mel-28(display_short)|uniprotkb:Maternal effect lethal protein 28(gene name synonym)|uniprotkb:C38D4.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459403|imex:IM-11985-374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N refseq:NP_497987.2|wormbase:C38D4.3|ensemblmetazoa:C38D4.3.1(transcript)|ensemblmetazoa:WBGene00003210(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060090"(molecular adaptor activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:UEMa5/rs0WbLvnqlwj+dYCYc6qI6239 intact-crc:014E7E51EE907C9A|rigid:TP3Kj0s0vyDz/iKfxa4ajaNFIUE false sufficient binding region:324-566("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:H2KZ49 uniprotkb:P55853 intact:EBI-6459392|ensemblmetazoa:T10B11.7a.1|uniprotkb:C6S3L8 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:hrde4_caeel(display_long)|uniprotkb:hrde-4(gene name)|psi-mi:hrde-4(display_short)|uniprotkb:Heritable RNAi deficient protein 4(gene name synonym)|uniprotkb:T10B11.7(orf name) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459389|imex:IM-11985-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T10B11.7a.1(transcript)|ensemblmetazoa:WBGene00020403(gene)|go:"GO:0031047"(gene silencing by RNA)|wormbase:T10B11.7b|refseq:NP_001040682.2|wormbase:T10B11.7a|refseq:NP_001040683.2 reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:e1ZNQX8Lo/f4Zw7iSGarIl+D0sk6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:0583CCA63DA6265F|rigid:z6n/nkyuFZ4AHl7goO4HIebNgC4 false sufficient binding region:325-545("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBE3 uniprotkb:Q18318 intact:EBI-2003873|ensemblmetazoa:F55F8.4.1|ensemblmetazoa:F55F8.4.2 intact:EBI-326762|ensemblmetazoa:C30B5.4.1 psi-mi:g5ebe3_caeel(display_long)|uniprotkb:cir-1(gene name)|psi-mi:cir-1(display_short)|uniprotkb:CELE_F55F8.4(orf name)|uniprotkb:F55F8.4(orf name) psi-mi:q18318_caeel(display_long)|uniprotkb:rbmx-2(gene name)|psi-mi:rbmx-2(display_short)|uniprotkb:C30B5.4(orf name)|uniprotkb:CELE_C30B5.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459423|imex:IM-11985-376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P91342(uniprot-removed-ac)|interpro:IPR040014|interpro:IPR019339|refseq:NP_491654.1|wormbase:F55F8.4|ensemblmetazoa:F55F8.4.1(transcript)|ensemblmetazoa:F55F8.4.2(transcript)|ensemblmetazoa:WBGene00018892(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048477"(oogenesis) refseq:NP_495237.1|wormbase:C30B5.4|ensemblmetazoa:WBGene00016245(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C30B5.4.1(transcript)|dip:DIP-26943N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WLmi45oz5gYwR5X4PaJ9/kUom1o6239 rogid:hnPi4Q/Z/uSY1xDRSQwr2mDxfjQ6239 intact-crc:779006E1F89F14B5|rigid:Pr4+tr9EBNTvfuFpjUjBKNdsW6I false - sufficient binding region:32-302("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94420 uniprotkb:Q94420 intact:EBI-320790|uniprotkb:Q94139|ensemblmetazoa:ZK858.4a.1 intact:EBI-320790|uniprotkb:Q94139|ensemblmetazoa:ZK858.4a.1 psi-mi:mel26_caeel(display_long)|uniprotkb:ZK858.4(orf name)|uniprotkb:mel-26(gene name)|psi-mi:mel-26(display_short) psi-mi:mel26_caeel(display_long)|uniprotkb:ZK858.4(orf name)|uniprotkb:mel-26(gene name)|psi-mi:mel-26(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459413|imex:IM-11985-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492449.2|wormbase:ZK858.4a|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|ensemblmetazoa:WBGene00003209(gene)|ensemblmetazoa:ZK858.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031674"(I band)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-27179N|reactome:R-CEL-5632684 refseq:NP_492449.2|wormbase:ZK858.4a|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|ensemblmetazoa:WBGene00003209(gene)|ensemblmetazoa:ZK858.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031674"(I band)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-27179N|reactome:R-CEL-5632684 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LdD7Fd/bItR1N1LukujfPZi0MqI6239 rogid:LdD7Fd/bItR1N1LukujfPZi0MqI6239 intact-crc:D63486A6F34C39BB|rigid:CCKTwrWPhvDgSrKHUCCwvK8MiVc false - sufficient binding region:3-245("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23237 uniprotkb:O62102 intact:EBI-314040|ensemblmetazoa:Y38A8.2.1 intact:EBI-317386|ensemblmetazoa:C47B2.4.1 psi-mi:psb3_caeel(display_long)|uniprotkb:pbs-3(gene name)|psi-mi:pbs-3(display_short)|uniprotkb:Y38A8.2(orf name) psi-mi:o62102_caeel(display_long)|uniprotkb:pbs-2(gene name)|psi-mi:pbs-2(display_short)|uniprotkb:C47B2.4(orf name)|uniprotkb:CELE_C47B2.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459433|imex:IM-11985-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8932339|refseq:NP_494913.1|wormbase:Y38A8.2|reactome:R-CEL-5632684|ensemblmetazoa:WBGene00003949(gene)|ensemblmetazoa:Y38A8.2.1(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-25063N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 reactome:R-CEL-187577|refseq:NP_493271.1|wormbase:C47B2.4|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023333|interpro:IPR029055|ensemblmetazoa:C47B2.4.1(transcript)|ensemblmetazoa:WBGene00003948(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5632684|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-6798695|reactome:R-CEL-8932339|reactome:R-CEL-68949|interpro:IPR035216|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XDQsAOH8E9LxVDloQ25KGEoFB6c6239 rogid:eg9h7mVfM8t5rvzr+jiN2fsj8Tw6239 intact-crc:0BA32F2BFC004306|rigid:Rg2WYsxbobHOW9d85j0Sz4/WWHc false - sufficient binding region:32-277("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18318 uniprotkb:P39745-1 intact:EBI-326762|ensemblmetazoa:C30B5.4.1 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 psi-mi:q18318_caeel(display_long)|uniprotkb:rbmx-2(gene name)|psi-mi:rbmx-2(display_short)|uniprotkb:C30B5.4(orf name)|uniprotkb:CELE_C30B5.4(orf name) psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459443|imex:IM-11985-378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495237.1|wormbase:C30B5.4|ensemblmetazoa:WBGene00016245(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C30B5.4.1(transcript)|dip:DIP-26943N ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hnPi4Q/Z/uSY1xDRSQwr2mDxfjQ6239 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 intact-crc:CAB4F3BB0D676A1E|rigid:6qY4e7EdkmrSwMMrYWzDls65lR8 false sufficient binding region:32-265("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21831 uniprotkb:Q18318 intact:EBI-360213|ensemblmetazoa:R07E5.3.1 intact:EBI-326762|ensemblmetazoa:C30B5.4.1 psi-mi:q21831_caeel(display_long)|uniprotkb:snfc-5(gene name)|psi-mi:snfc-5(display_short)|uniprotkb:CELE_R07E5.3(orf name)|uniprotkb:R07E5.3(orf name) psi-mi:q18318_caeel(display_long)|uniprotkb:rbmx-2(gene name)|psi-mi:rbmx-2(display_short)|uniprotkb:C30B5.4(orf name)|uniprotkb:CELE_C30B5.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459453|imex:IM-11985-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:R07E5.3.1(transcript)|ensemblmetazoa:WBGene00011111(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|refseq:NP_497890.1|wormbase:R07E5.3|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|reactome:R-CEL-8939243 refseq:NP_495237.1|wormbase:C30B5.4|ensemblmetazoa:WBGene00016245(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C30B5.4.1(transcript)|dip:DIP-26943N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:xJdCCAUyt1lmFvLa0ZpqfBxhlLQ6239 rogid:hnPi4Q/Z/uSY1xDRSQwr2mDxfjQ6239 intact-crc:8EDE4EC5189CD56E|rigid:2MzLwIsaAOM6Gu6bXJBOCPniZd8 false - sufficient binding region:32-265("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18318 uniprotkb:P30640 intact:EBI-326762|ensemblmetazoa:C30B5.4.1 intact:EBI-2002595|ensemblmetazoa:R08D7.1.1 psi-mi:q18318_caeel(display_long)|uniprotkb:rbmx-2(gene name)|psi-mi:rbmx-2(display_short)|uniprotkb:C30B5.4(orf name)|uniprotkb:CELE_C30B5.4(orf name) psi-mi:bud13_caeel(display_long)|uniprotkb:R08D7.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459463|imex:IM-11985-380 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495237.1|wormbase:C30B5.4|ensemblmetazoa:WBGene00016245(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:C30B5.4.1(transcript)|dip:DIP-26943N refseq:NP_498982.1|wormbase:R08D7.1|interpro:IPR018609|ensemblmetazoa:R08D7.1.1(transcript)|ensemblmetazoa:WBGene00011142(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0070274"(RES complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hnPi4Q/Z/uSY1xDRSQwr2mDxfjQ6239 rogid:dLP4vgxP5KCPHP9rJDHEVQLHMyw6239 intact-crc:84EA8C8716F61328|rigid:u1yYIttQ5YzNzTXArtTXaiM4H5c false sufficient binding region:32-265("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76371 uniprotkb:O17071 intact:EBI-317201|ensemblmetazoa:F56H1.4.1 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 psi-mi:prs6a_caeel(display_long)|uniprotkb:rpt-5(gene name)|psi-mi:rpt-5(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 5(gene name synonym)|uniprotkb:F56H1.4(orf name) psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459473|imex:IM-11985-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_491672.1|wormbase:F56H1.4|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F56H1.4.1(transcript)|ensemblmetazoa:WBGene00004505(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-CEL-5632684|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|interpro:IPR035254 refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:JW4UPtYlusTCwjDWZOAyH30g+Sw6239 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 intact-crc:6F18CF64FBA3F107|rigid:qPrgZCPwA9r+67qFvKwR+XdC2pQ false sufficient binding region:3-196("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:G5ECY0 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459493|imex:IM-11985-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:FF15E64F5000C30D|rigid:mz9oq/7vuNSabSVim6tVZswsrVA false - sufficient binding region:3-135("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21993 uniprotkb:P52554 intact:EBI-323701|ensemblmetazoa:R151.9.1 intact:EBI-367856|ensemblmetazoa:F21C3.5.1 psi-mi:pfd5_caeel(display_long)|uniprotkb:R151.9(orf name)|uniprotkb:pfd-5(gene name)|psi-mi:pfd-5(display_short) psi-mi:pfd6_caeel(display_long)|uniprotkb:F21C3.5(orf name)|uniprotkb:pfd-6(gene name)|psi-mi:pfd-6(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459483|imex:IM-11985-382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498582.1|wormbase:R151.9|ensemblmetazoa:WBGene00020112(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|ensemblmetazoa:R151.9.1(transcript)|dip:DIP-25712N interpro:IPR009053(Prefoldin)|refseq:NP_492058.1|wormbase:F21C3.5|interpro:IPR002777(Prefoldin beta-like)|ensemblmetazoa:F21C3.5.1(transcript)|ensemblmetazoa:WBGene00009004(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vpZze2rqh9a2h5G80I7F5Xn2Css6239 rogid:6/DTWsbriiGyKt9WCc29b0hG7z06239 intact-crc:CF22919857346582|rigid:xAzk7U28yJhxKPhZexDlLsV4frg false sufficient binding region:3-152("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95Q17 uniprotkb:Q95YF3 intact:EBI-1533863|uniprotkb:Q9XWF7|ensemblmetazoa:Y54E5B.3b.1 intact:EBI-314525|ensemblmetazoa:C07H6.5.1 psi-mi:med7_caeel(display_long)|uniprotkb:let-49(gene name)|psi-mi:let-49(display_short)|uniprotkb:mdt-7(gene name synonym)|uniprotkb:med-7(gene name synonym)|uniprotkb:Y54E5B.3(orf name)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:CeMED7(gene name synonym)|uniprotkb:Lethal protein 49(gene name synonym) psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459513|imex:IM-11985-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493585.1|refseq:NP_493586.1|wormbase:Y54E5B.3a|wormbase:Y54E5B.3b|interpro:IPR009244(MED7)|interpro:IPR037212|ensemblmetazoa:WBGene00002324(gene)|ensemblmetazoa:Y54E5B.3b.1(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex) refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:2vnSzQQim7krI84wwUv0n3B+TB86239 rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239 intact-crc:918207A846770055|rigid:z7o6Ubo3l1zycoc+NqdC+ZOpKaw false sufficient binding region:31-129("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34440 uniprotkb:P62784 intact:EBI-2001876|ensemblmetazoa:F54C8.2.1 intact:EBI-2001857|uniprotkb:O02619|uniprotkb:P02306|uniprotkb:P18678|uniprotkb:Q7JNV2|ensemblmetazoa:B0035.9.1|ensemblmetazoa:C50F4.7.1|ensemblmetazoa:F07B7.9.1|ensemblmetazoa:F17E9.12.1|ensemblmetazoa:F22B3.1.1|ensemblmetazoa:F45F2.3.1|ensemblmetazoa:F54E12.3.1|ensemblmetazoa:F55G1.11.1|ensemblmetazoa:K03A1.6.1|ensemblmetazoa:K06C4.10.1|ensemblmetazoa:K06C4.2.1|ensemblmetazoa:T10C6.14.1|ensemblmetazoa:T23D8.5.1|ensemblmetazoa:ZK131.1.1|ensemblmetazoa:ZK131.4.1|ensemblmetazoa:ZK131.8.1 psi-mi:hcp3l_caeel(display_long)|uniprotkb:cpar-1(gene name)|psi-mi:cpar-1(display_short)|uniprotkb:CENP-A-related protein 1(gene name synonym)|uniprotkb:F54C8.2(orf name)|uniprotkb:Centromeric protein A related(gene name synonym) psi-mi:h4_caeel(display_long)|uniprotkb:his-1(gene name)|psi-mi:his-1(display_short)|uniprotkb:his-5(gene name)|psi-mi:his-5(display_short)|uniprotkb:his-10(gene name)|psi-mi:his-10(display_short)|uniprotkb:his-14(gene name)|psi-mi:his-14(display_short)|uniprotkb:his-18(gene name)|psi-mi:his-18(display_short)|uniprotkb:his-26(gene name)|psi-mi:his-26(display_short)|uniprotkb:his-28(gene name)|psi-mi:his-28(display_short)|uniprotkb:his-31(gene name)|psi-mi:his-31(display_short)|uniprotkb:his-37(gene name)|psi-mi:his-37(display_short)|uniprotkb:his-38(gene name)|psi-mi:his-38(display_short)|uniprotkb:his-46(gene name)|psi-mi:his-46(display_short)|uniprotkb:his-50(gene name)|psi-mi:his-50(display_short)|uniprotkb:his-56(gene name)|psi-mi:his-56(display_short)|uniprotkb:his-60(gene name)|psi-mi:his-60(display_short)|uniprotkb:his-64(gene name)|psi-mi:his-64(display_short)|uniprotkb:his-67(gene name)|psi-mi:his-67(display_short)|uniprotkb:T10C6.14(orf name)|uniprotkb:F45F2.3(orf name)|uniprotkb:ZK131.4(orf name)|uniprotkb:ZK131.8(orf name)|uniprotkb:K06C4.10(orf name)|uniprotkb:ZK131.1(orf name)|uniprotkb:K06C4.2(orf name)|uniprotkb:F17E9.12(orf name)|uniprotkb:C50F4.7(orf name)|uniprotkb:K03A1.6(orf name)|uniprotkb:B0035.9(orf name)|uniprotkb:F07B7.9(orf name)|uniprotkb:F54E12.3(orf name)|uniprotkb:F55G1.11(orf name)|uniprotkb:F22B3.1(orf name)|uniprotkb:T23D8.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459503|imex:IM-11985-384 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499073.1|wormbase:F54C8.2|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|ensemblmetazoa:F54C8.2.1(transcript)|ensemblmetazoa:WBGene00010036(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_492641.1|refseq:NP_496889.1|refseq:NP_496893.1|refseq:NP_496896.1|refseq:NP_501203.2|refseq:NP_501406.1|refseq:NP_502133.1|refseq:NP_502139.1|refseq:NP_502154.1|refseq:NP_505200.1|refseq:NP_505275.1|refseq:NP_505291.1|refseq:NP_505298.1|refseq:NP_505466.1|refseq:NP_507034.1|refseq:NP_509231.1|interpro:IPR009072(Histone-fold)|interpro:IPR001951(Histone H4)|interpro:IPR019809|wormbase:B0035.9|wormbase:C50F4.7|wormbase:F07B7.9|wormbase:F17E9.12|wormbase:F22B3.1|wormbase:F45F2.3|wormbase:F54E12.3|wormbase:F55G1.11|wormbase:K03A1.6|wormbase:K06C4.10|wormbase:K06C4.2|wormbase:T10C6.14|wormbase:T23D8.5|wormbase:ZK131.1|wormbase:ZK131.4|wormbase:ZK131.8|reactome:R-CEL-2299718|reactome:R-CEL-3214841|reactome:R-CEL-3214842|reactome:R-CEL-3214847|reactome:R-CEL-3214858|reactome:R-CEL-2559580|reactome:R-CEL-5578749|reactome:R-CEL-5693565|reactome:R-CEL-8936459|interpro:IPR035425|reactome:R-CEL-427413|reactome:R-CEL-9018519|reactome:R-CEL-4551638|reactome:R-CEL-201722|reactome:R-CEL-212300|reactome:R-CEL-3214815|reactome:R-CEL-427359|reactome:R-CEL-5625886|reactome:R-CEL-73772|ensemblmetazoa:B0035.9.1(transcript)|ensemblmetazoa:C50F4.7.1(transcript)|ensemblmetazoa:F07B7.9.1(transcript)|ensemblmetazoa:F17E9.12.1(transcript)|ensemblmetazoa:F22B3.1.1(transcript)|ensemblmetazoa:F45F2.3.1(transcript)|ensemblmetazoa:F54E12.3.1(transcript)|ensemblmetazoa:F55G1.11.1(transcript)|ensemblmetazoa:K03A1.6.1(transcript)|ensemblmetazoa:K06C4.10.1(transcript)|ensemblmetazoa:K06C4.2.1(transcript)|ensemblmetazoa:T10C6.14.1(transcript)|ensemblmetazoa:T23D8.5.1(transcript)|ensemblmetazoa:WBGene00001875(gene)|ensemblmetazoa:WBGene00001879(gene)|ensemblmetazoa:WBGene00001884(gene)|ensemblmetazoa:WBGene00001888(gene)|ensemblmetazoa:WBGene00001892(gene)|ensemblmetazoa:WBGene00001900(gene)|ensemblmetazoa:WBGene00001902(gene)|ensemblmetazoa:WBGene00001905(gene)|ensemblmetazoa:WBGene00001911(gene)|ensemblmetazoa:WBGene00001912(gene)|ensemblmetazoa:WBGene00001920(gene)|ensemblmetazoa:WBGene00001924(gene)|ensemblmetazoa:WBGene00001930(gene)|ensemblmetazoa:WBGene00001934(gene)|ensemblmetazoa:WBGene00001938(gene)|ensemblmetazoa:WBGene00001941(gene)|ensemblmetazoa:ZK131.1.1(transcript)|ensemblmetazoa:ZK131.4.1(transcript)|ensemblmetazoa:ZK131.8.1(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:O2olKPBZ67qT1Ttk4fL5YuZxE3I6239 rogid:nOpb0cRdbKnTImn4dpinHILzU+U6239 intact-crc:BFD632603C760154|rigid:5RZMX+pzuGCk42LcthF1wzdxvzs false sufficient binding region:31-261("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:O17586 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-315388|ensemblmetazoa:C15H11.7.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:psa6_caeel(display_long)|uniprotkb:pas-1(gene name)|psi-mi:pas-1(display_short)|uniprotkb:C15H11.7(orf name)|uniprotkb:Proteasome subunit alpha 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459523|imex:IM-11985-386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_506571.1|wormbase:C15H11.7|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034642|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:C15H11.7.1(transcript)|ensemblmetazoa:WBGene00003922(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:mfBWpXrDLE3WiKEpDUQXyIxSlV46239 intact-crc:6E737EF70D37D02F|rigid:LNjQfJ3xoxzepAlQa+2he7R8rEY false sufficient binding region:306-774("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18547 uniprotkb:Q9XVU8 intact:EBI-314981|ensemblmetazoa:C39E9.13.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:q18547_caeel(display_long)|uniprotkb:rfc-3(gene name)|psi-mi:rfc-3(display_short)|uniprotkb:CELE_C39E9.13(orf name)|uniprotkb:C39E9.13(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459533|imex:IM-11985-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502517.1|wormbase:C39E9.13|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-110320|reactome:R-CEL-69091|ensemblmetazoa:C39E9.13.1(transcript)|ensemblmetazoa:WBGene00004339(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|go:"GO:0005663"(DNA replication factor C complex)|dip:DIP-27479N ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:9i4qy+nQFgxA2CsSmCxrFmzOsfM6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:6901E2F3461D8315|rigid:h5eBHckdxpHZOwZyWF/RPupP3ac false - sufficient binding region:306-774("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q8WQC0-3 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-6459543|ensemblmetazoa:F56B6.2b.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q8wqc0-3(display_long)|uniprotkb:Protein C2-RGS(gene name synonym)|uniprotkb:Regulator of G-protein signaling c2(gene name synonym)|uniprotkb:F56B6.2(orf name)|uniprotkb:rgs-7(gene name)|psi-mi:rgs-7(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459548|imex:IM-11985-388 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 ensemblmetazoa:F56B6.2b.1(transcript)|ensemblmetazoa:WBGene00004350(gene)|intact:EBI-6499941(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:b5aipypkEQmIRlZRHwWc393n5gE6239 intact-crc:52EB04DD561FEE45|rigid:D6/2yLSpy5jhb3ijBaBaWHqb5Ck false sufficient binding region:306-774("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91082 uniprotkb:Q9XVU8 intact:EBI-2002373|uniprotkb:A0A0K3AWT5|ensemblmetazoa:C23H3.1a.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:egl26_caeel(display_long)|uniprotkb:egl-26(gene name)|psi-mi:egl-26(display_short)|uniprotkb:Putative acyltransferase egl-26(gene name synonym)|uniprotkb:cog-4(gene name synonym)|uniprotkb:egl-48(gene name synonym)|uniprotkb:C23H3.1(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459568|imex:IM-11985-390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493652.1|wormbase:C23H3.1a|interpro:IPR007053(NC)|wormbase:C23H3.1b|ensemblmetazoa:C23H3.1a.1(transcript)|ensemblmetazoa:WBGene00001193(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002119"(nematode larval development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:TEM2NJQmEPUiCvqWHItpREWKEII6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:D5BEBA4DF4D7FB02|rigid:PbBHfVYv2kH19vtnL4N8xGmSVUY false - sufficient binding region:306-706("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:G4RT11 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-6458195|ensemblmetazoa:B0511.9c.1|uniprotkb:A9D8E6|uniprotkb:G4RT06|uniprotkb:H2KYB5 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:cdc26_caeel(display_long)|uniprotkb:Cell division cycle protein 26 homolog(gene name synonym)|uniprotkb:mat-4(gene name synonym)|uniprotkb:tag-265(gene name synonym)|uniprotkb:B0511.9(orf name)|uniprotkb:cdc-26(gene name)|psi-mi:cdc-26(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459558|imex:IM-11985-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 ensemblmetazoa:B0511.9c.1(transcript)|ensemblmetazoa:WBGene00015235(gene)|go:"GO:0005634"(nucleus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:B0511.9a|wormbase:B0511.9b|wormbase:B0511.9d|refseq:NP_001251445.1|refseq:NP_740913.3|refseq:NP_740914.2|refseq:NP_001251447.1|wormbase:B0511.9c|dip:DIP-26086N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:4EiUm/eby0CTOnoyalmBYdJZmOE6239 intact-crc:C5E9522A809DB3B3|rigid:RctTKDl5Leq8AIdjDgl2OMpB8Wk false sufficient binding region:306-706("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19749 uniprotkb:Q9XVU8 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459578|imex:IM-11985-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:E9B1A7C25B936390|rigid:Sj9ezVdRxI+OC2JGUQYenLt7lRs false - sufficient binding region:306-706("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q09601-1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459588|imex:IM-11985-392 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:D9012FB79638B46A|rigid:ak02/pJMC+sJgLyIoreEe3ygje8 false sufficient binding region:306-706("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q95XY1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459598|imex:IM-11985-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:48D78C417468A897|rigid:sBRr9WlU/YMjf4WsboyyrE3Kg28 false sufficient binding region:306-706("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q65XX1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459608|imex:IM-11985-394 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:77251B6B7B721D6F|rigid:1hw0x3+GfLWC9/K5jJCfy3WeJlg false sufficient binding region:306-706("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EF84 uniprotkb:P34475 intact:EBI-2003997|ensemblmetazoa:C45G3.5.1 intact:EBI-323304|ensemblmetazoa:F58A4.8.1 psi-mi:gip2_caeel(display_long)|uniprotkb:C45G3.5(orf name)|uniprotkb:gip-2(gene name)|psi-mi:gip-2(display_short) psi-mi:tbg_caeel(display_long)|uniprotkb:tbg-1(gene name)|psi-mi:tbg-1(display_short)|uniprotkb:F58A4.8(orf name)|uniprotkb:Gamma-tubulin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459628|imex:IM-11985-396 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5FC27(uniprot-removed-ac)|refseq:NP_001021044.1|wormbase:C45G3.5|ensemblmetazoa:C45G3.5.1(transcript)|ensemblmetazoa:WBGene00044008(gene)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0030056"(hemidesmosome) refseq:NP_499131.1|wormbase:F58A4.8|ensemblmetazoa:F58A4.8.1(transcript)|ensemblmetazoa:WBGene00006540(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:1903436"(regulation of mitotic cytokinetic process)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|dip:DIP-26367N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PCFmF0ZM9NkcqMNWQcuChHwghPg6239 rogid:Md2V65A3uxG1lolcbk5VIH9Gpfs6239 intact-crc:5506DD5B804A77BA|rigid:v5nogAyG+Jr+vVk9Xw9klUVyzuU false sufficient binding region:305-642("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q2V0X4 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-6456854 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q2v0x4_caeel(display_long)|uniprotkb:cogc-3(gene name)|psi-mi:cogc-3(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459618|imex:IM-11985-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007265(Sec34-like protein) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:G/tGsp4WwyIUGdFnfOzoBMkgOrM6239 intact-crc:3F1F75ACB34314E3|rigid:A00NGVsOufGpOfqCYtplYQFIC3U false sufficient binding region:306-571("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECR7 uniprotkb:Q21443 intact:EBI-330567|ensemblmetazoa:Y41C4A.10.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:g5ecr7_caeel(display_long)|uniprotkb:3L686(gene name synonym)|uniprotkb:elb-1(gene name)|psi-mi:elb-1(display_short)|uniprotkb:Y41C4A.10(orf name)|uniprotkb:CELE_Y41C4A.10(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459638|imex:IM-11985-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9XWU4(uniprot-removed-ac)|refseq:NP_499517.1|reactome:R-CEL-674695|reactome:R-CEL-6796648|wormbase:Y41C4A.10|interpro:IPR039049|interpro:IPR029071|reactome:R-CEL-1234176|reactome:R-CEL-983168|reactome:R-CEL-8951664|ensemblmetazoa:WBGene00001235(gene)|ensemblmetazoa:Y41C4A.10.1(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|reactome:R-CEL-75955|reactome:R-CEL-112382 reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:nd6q1xH1t5OIdfLT3hHtTS3gTqU6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:CF701DA3E7DE18EE|rigid:mXhIkp2y5jqcb9DlH6MqdTaTFqY false - sufficient binding region:301-566("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDE7 uniprotkb:Q18282 intact:EBI-324390|ensemblmetazoa:Y39G10AR.12a.1 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 psi-mi:g5ede7_caeel(display_long)|uniprotkb:tpxl-1(gene name)|psi-mi:tpxl-1(display_short)|uniprotkb:Y39G10AR.12(orf name)|uniprotkb:1C866(orf name)|uniprotkb:CELE_Y39G10AR.12(orf name) psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459658|imex:IM-11985-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740805.1|uniprotkb:Q95XR5(uniprot-removed-ac)|wormbase:Y39G10AR.12a|ensemblmetazoa:WBGene00021470(gene)|go:"GO:0000235"(astral microtubule)|ensemblmetazoa:Y39G10AR.12a.1(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:L8qyImbTKWJWTK7yRTb2pY3sJ1s6239 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 intact-crc:F06555BB1024ECA1|rigid:injt2qg/u3MVRJRUU31755ZAqBw false sufficient binding region:301-451("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:Q21443 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459648|imex:IM-11985-398 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:C12A6565F81E9B50|rigid:QsgKqGXg25N3GdvB4igWBWbzr/Y false - sufficient binding region:301-504("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19749 uniprotkb:Q21443 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459668|imex:IM-11985-400 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:1BB5C4B866608634|rigid:dN/A82tQfWbQaBfKE9XfGaUy9vw false - sufficient binding region:301-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 intact:EBI-6457133 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-6306363 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:ebi6306363(display_short)|psi-mi:EBI-6457133(display_long)|intact:F39H11.2x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459678|imex:IM-11985-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 - intact-crc:B6BF5EDC0C3FE8AE false sufficient binding region:301-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:Q9U3C1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-2004353|ensemblmetazoa:K07F5.13b.1 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:q9u3c1_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459698|imex:IM-11985-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N refseq:NP_501771.1|wormbase:K07F5.13b|interpro:IPR024864|interpro:IPR025712|interpro:IPR025574|ensemblmetazoa:K07F5.13b.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:PBUFj0HXUAAcVEWkwfLNogGoZNQ6239 intact-crc:6A625D772255A91D|rigid:GfgAvKVbdMk8zBTmDFV9B3ReOvE false sufficient binding region:301-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:Q21295 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-2004307|uniprotkb:Q21296|ensemblmetazoa:K07F5.13a.1 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:q21295_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459688|imex:IM-11985-402 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N refseq:NP_501772.1|wormbase:K07F5.13a|interpro:IPR024864|interpro:IPR025712|ensemblmetazoa:K07F5.13a.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:CgqZPl+7gsTQJxOMbCCLLuEiUh46239 intact-crc:3452B69131A88895|rigid:wtNmN/iQMmOl0TiXe11eXD31E9I false sufficient binding region:301-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01585 uniprotkb:Q21443 intact:EBI-2004403|ensemblmetazoa:K09H11.3.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:o01585_caeel(display_long)|uniprotkb:CELE_K09H11.3(orf name)|uniprotkb:rga-3(gene name)|psi-mi:rga-3(display_short)|uniprotkb:K09H11.3(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459708|imex:IM-11985-404 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504503.1|wormbase:K09H11.3|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR042869|ensemblmetazoa:K09H11.3.1(transcript)|ensemblmetazoa:WBGene00019600(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OmLo3eyH9KRRr+1RpDnLNNzl2Zs6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:121FAF3506A2C84B|rigid:zb5Zadu1pBhyulGFJEgoCvC8Rp4 false - sufficient binding region:301-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:P30642 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-311981|ensemblmetazoa:R08D7.3.1 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:eif3d_caeel(display_long)|uniprotkb:R08D7.3(orf name)|uniprotkb:eif-3.D(gene name)|psi-mi:eif-3.D(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459718|imex:IM-11985-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N reactome:R-CEL-72649|ensemblmetazoa:R08D7.3.1(transcript)|ensemblmetazoa:WBGene00001227(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|refseq:NP_498984.1|wormbase:R08D7.3|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|dip:DIP-25819N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:CvW4IPXX62lvTWXOvGSZttuD3cs6239 intact-crc:8DB535B9C7E7E819|rigid:yvH3zbVPARi9ko9QMqIkcwCwsbs false sufficient binding region:301-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:Q21443 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459728|imex:IM-11985-406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:9BC1C0DCE35D69BE|rigid:tW0S7+GDrN+/Ri887fm9FDGocF4 false - sufficient binding region:301-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86S68 uniprotkb:Q21443 intact:EBI-3902879|ensemblmetazoa:Y54E10A.15.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:q86s68_caeel(display_long)|uniprotkb:Y54E10A.15(orf name)|uniprotkb:cdt-1(gene name)|psi-mi:cdt-1(display_short)|uniprotkb:CELE_Y54E10A.15(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459738|imex:IM-11985-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036390|reactome:R-CEL-68949|interpro:IPR014939(DNA replication factor CDT1-like)|refseq:NP_001040707.1|wormbase:Y54E10A.15|interpro:IPR032054|ensemblmetazoa:WBGene00000413(gene)|ensemblmetazoa:Y54E10A.15.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|reactome:R-CEL-68962|interpro:IPR038090 reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:QK1s2+ecB78fETotgKLzn7M4Wrc6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:35C872939E8319AC|rigid:IxjRVacGk6w7a0ecwodOg1NH5FU false - sufficient binding region:301-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:Q21443 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459748|imex:IM-11985-408 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:3F4C70F64A9F8450|rigid:56prVTf27cyKVDKso2oD1Rsfnac false - sufficient binding region:301-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q21443 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459758|imex:IM-11985-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:930597EEC2418A84|rigid:gfpqd9RIq0HxD83V5daKqy8ihxg false - sufficient binding region:301-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:G5ECG0 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459768|imex:IM-11985-410 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:106E19F631216ED1|rigid:XtDK495ITw3Flp0p+iKk2PFqfRw false sufficient binding region:301-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:Q95QC4 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459778|imex:IM-11985-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 intact-crc:13039C387A28B0E6|rigid:YS59qrhwGD2eOF5Ruh6CrcspdEw false sufficient binding region:301-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:Q9GS00 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-331408|ensemblmetazoa:Y59A8A.1.1 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:csn1_caeel(display_long)|uniprotkb:Y59A8A.1(orf name)|uniprotkb:csn-1(gene name)|psi-mi:csn-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459798|imex:IM-11985-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 refseq:NP_507507.1|wormbase:Y59A8A.1|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-26112N|ensemblmetazoa:WBGene00000813(gene)|ensemblmetazoa:Y59A8A.1.1(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR019585|interpro:IPR033008|interpro:IPR036390|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:OpmKXZHWN+haPePSg+liDfvUe4E6239 intact-crc:CC02ABA4E960AB2B|rigid:R417nCUXBHDDBRzp2sbC2SDZtOE false - sufficient binding region:297-447("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N359 uniprotkb:O01422 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 intact:EBI-331413|ensemblmetazoa:B0025.2.1|ensemblmetazoa:B0025.2.2 psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:csn2_caeel(display_long)|uniprotkb:B0025.2(orf name)|uniprotkb:csn-2(gene name)|psi-mi:csn-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459788|imex:IM-11985-412 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 refseq:NP_491740.1|wormbase:B0025.2|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-24665N|ensemblmetazoa:B0025.2.1(transcript)|ensemblmetazoa:B0025.2.2(transcript)|ensemblmetazoa:WBGene00000814(gene)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 rogid:qwX/mKYLxZitZLkfNa3RPYDLYyo6239 intact-crc:8EE4185157AE0C25|rigid:5/nNc3VxeOiGRzVTVVMnb48GQM4 false - sufficient binding region:298-495("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34511 uniprotkb:P54812 intact:EBI-2002777|ensemblmetazoa:K06H7.3.1|ensemblmetazoa:K06H7.3.2|ensemblmetazoa:K06H7.3.3 intact:EBI-320265|uniprotkb:Q18560|ensemblmetazoa:C41C4.8.1|ensemblmetazoa:C41C4.8.2 psi-mi:vms1_caeel(display_long)|uniprotkb:vms-1(gene name)|psi-mi:vms-1(display_short)|uniprotkb:K06H7.3(orf name) psi-mi:tera2_caeel(display_long)|uniprotkb:C41C4.8(orf name)|uniprotkb:Cell division cycle-related protein 48.2(gene name synonym)|uniprotkb:p97/CDC48 homolog 2(gene name synonym)|uniprotkb:cdc-48.2(gene name)|psi-mi:cdc-48.2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459808|imex:IM-11985-414 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498765.1|wormbase:K06H7.3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041175|interpro:IPR041540|ensemblmetazoa:K06H7.3.1(transcript)|ensemblmetazoa:K06H7.3.2(transcript)|ensemblmetazoa:K06H7.3.3(transcript)|ensemblmetazoa:WBGene00019457(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0030425"(dendrite)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0046872"(metal ion binding) refseq:NP_495705.1|wormbase:C41C4.8|ensemblmetazoa:C41C4.8.1(transcript)|ensemblmetazoa:C41C4.8.2(transcript)|ensemblmetazoa:WBGene00008053(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|reactome:R-CEL-3371511|reactome:R-CEL-9013407|reactome:R-CEL-110320|reactome:R-CEL-6798695|reactome:R-CEL-382556|reactome:R-CEL-532668|reactome:R-CEL-5689877|dip:DIP-26566N|reactome:R-CEL-8876725|reactome:R-CEL-5358346 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Sz+Ye8wbg0UPbpmNBKUsQ/G6Uns6239 rogid:8orzUPvtC7n65UHKceyBId+MP0Q6239 intact-crc:2020BC5A62BD367A|rigid:/VsfJdd4VtSZMOolXZHNF3zaccQ false sufficient binding region:295-618("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61708 uniprotkb:O62333 intact:EBI-315255|ensemblmetazoa:R119.4.1 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 psi-mi:o61708_caeel(display_long)|uniprotkb:pqn-59(gene name)|psi-mi:pqn-59(display_short)|uniprotkb:CELE_R119.4(orf name)|uniprotkb:R119.4(orf name) psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459818|imex:IM-11985-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490727.1|wormbase:R119.4|ensemblmetazoa:R119.4.1(transcript)|ensemblmetazoa:WBGene00004143(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR009060(UBA-like)|dip:DIP-25020N interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:K83JJthOIli1KrkmuKJbMtYpX7I6239 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 intact-crc:86DB0D0C73E515E8|rigid:4Bu5EWy3HwwgSKPrrcJWiz0tSoU false sufficient binding region:284-712("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61708 uniprotkb:P34331-2 intact:EBI-315255|ensemblmetazoa:R119.4.1 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 psi-mi:o61708_caeel(display_long)|uniprotkb:pqn-59(gene name)|psi-mi:pqn-59(display_short)|uniprotkb:CELE_R119.4(orf name)|uniprotkb:R119.4(orf name) psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459828|imex:IM-11985-416 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490727.1|wormbase:R119.4|ensemblmetazoa:R119.4.1(transcript)|ensemblmetazoa:WBGene00004143(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR009060(UBA-like)|dip:DIP-25020N intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:K83JJthOIli1KrkmuKJbMtYpX7I6239 rogid:u830S0jdkV753ilx7DbxmhPocv86239 intact-crc:1670C26AC424F396|rigid:FgPq8Bioy7XitPYxXg9ImiYovak false sufficient binding region:284-470("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:Q94361-3 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-1459360|ensemblmetazoa:W10D5.3g.1|ensemblmetazoa:W10D5.3g.2 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:q94361-3(display_long)|uniprotkb:E3 SUMO-protein transferase gei-17(gene name synonym)|uniprotkb:g(isoform synonym)|uniprotkb:gei-17(gene name)|psi-mi:gei-17(display_short)|uniprotkb:Gex-3-interacting protein 17(gene name synonym)|uniprotkb:W10D5.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459838|imex:IM-11985-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 intact:EBI-323258(isoform-parent)|ensemblmetazoa:W10D5.3g.1(transcript)|ensemblmetazoa:W10D5.3g.2(transcript)|ensemblmetazoa:WBGene00001574(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:S6Qy93VvrZzegwFS6o+tnB46yks6239 intact-crc:769D726B8DF438CE|rigid:ry+6Pm09NnwIhZHJRnFonQxgS60 false - sufficient binding region:270-685("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17586 uniprotkb:Q09583 intact:EBI-315388|ensemblmetazoa:C15H11.7.1 intact:EBI-315406|ensemblmetazoa:ZK945.2.1|ensemblmetazoa:ZK945.2.2 psi-mi:psa6_caeel(display_long)|uniprotkb:pas-1(gene name)|psi-mi:pas-1(display_short)|uniprotkb:C15H11.7(orf name)|uniprotkb:Proteasome subunit alpha 1(gene name synonym) psi-mi:psa3_caeel(display_long)|uniprotkb:pas-7(gene name)|psi-mi:pas-7(display_short)|uniprotkb:ZK945.2(orf name)|uniprotkb:Proteasome subunit alpha 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459848|imex:IM-11985-418 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506571.1|wormbase:C15H11.7|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034642|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:C15H11.7.1(transcript)|ensemblmetazoa:WBGene00003922(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 refseq:NP_496177.2|wormbase:ZK945.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:WBGene00003928(gene)|ensemblmetazoa:ZK945.2.1(transcript)|ensemblmetazoa:ZK945.2.2(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|interpro:IPR037555|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mfBWpXrDLE3WiKEpDUQXyIxSlV46239 rogid:OOdurA40PpJd/0X3BA8Z5ZWqCuM6239 intact-crc:2CFC24C6C8690134|rigid:mtx/Q4qiv/GmOf+IPb+CRdmPZgM false - sufficient binding region:28-250("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76577 uniprotkb:O61792 intact:EBI-324401|ensemblmetazoa:K07D4.3.1 intact:EBI-324407|ensemblmetazoa:R12E2.3.1 psi-mi:psde_caeel(display_long)|uniprotkb:K07D4.3(orf name)|uniprotkb:rpn-11(gene name)|psi-mi:rpn-11(display_short)|uniprotkb:26S proteasome regulatory subunit rpn11(gene name synonym) psi-mi:o61792_caeel(display_long)|uniprotkb:rpn-8(gene name)|psi-mi:rpn-8(display_short)|uniprotkb:R12E2.3(orf name)|uniprotkb:CELE_R12E2.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459858|imex:IM-11985-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024969|refseq:NP_494712.1|wormbase:K07D4.3|interpro:IPR000555(Mov34/MPN/PAD-1)|ensemblmetazoa:K07D4.3.1(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070628"(proteasome binding)|ensemblmetazoa:WBGene00004467(gene)|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5689901|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR037518|interpro:IPR035299|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-8932339|reactome:R-CEL-187577|reactome:R-CEL-5687128 interpro:IPR024969|refseq:NP_491319.1|wormbase:R12E2.3|interpro:IPR000555(Mov34/MPN/PAD-1)|ensemblmetazoa:R12E2.3.1(transcript)|ensemblmetazoa:WBGene00004464(gene)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR033858|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR037518|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128|reactome:R-CEL-8932339 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:lmdcUc0hxOvaDgLEI+rHKhv3bnI6239 rogid:W/94trr894y/hNnW+ibZRLHDRlg6239 intact-crc:01D07E420C948947|rigid:wz4rafpqZH9kLPtKDv/RUjPLXyE false sufficient binding region:28-233("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDE7 uniprotkb:Q18282 intact:EBI-324390|ensemblmetazoa:Y39G10AR.12a.1 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 psi-mi:g5ede7_caeel(display_long)|uniprotkb:tpxl-1(gene name)|psi-mi:tpxl-1(display_short)|uniprotkb:Y39G10AR.12(orf name)|uniprotkb:1C866(orf name)|uniprotkb:CELE_Y39G10AR.12(orf name) psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459878|imex:IM-11985-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740805.1|uniprotkb:Q95XR5(uniprot-removed-ac)|wormbase:Y39G10AR.12a|ensemblmetazoa:WBGene00021470(gene)|go:"GO:0000235"(astral microtubule)|ensemblmetazoa:Y39G10AR.12a.1(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:L8qyImbTKWJWTK7yRTb2pY3sJ1s6239 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 intact-crc:B9B360A1A3B592DF|rigid:injt2qg/u3MVRJRUU31755ZAqBw false - sufficient binding region:28-193("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19130 uniprotkb:Q19699 intact:EBI-331451|ensemblmetazoa:F07A11.2a.1|ensemblmetazoa:F07A11.2a.2|ensemblmetazoa:F07A11.2a.3|ensemblmetazoa:F07A11.2a.4 intact:EBI-6458880|ensemblmetazoa:F22B3.4.1|ensemblmetazoa:F22B3.4.2 psi-mi:q19130_caeel(display_long)|uniprotkb:gfat-1(gene name)|psi-mi:gfat-1(display_short)|uniprotkb:CELE_F07A11.2(orf name)|uniprotkb:F07A11.2(orf name) psi-mi:q19699_caeel(display_long)|uniprotkb:gfat-2(gene name)|psi-mi:gfat-2(display_short)|uniprotkb:CELE_F22B3.4(orf name)|uniprotkb:F22B3.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459888|imex:IM-11985-422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-446210|refseq:NP_496480.1|wormbase:F07A11.2a|dip:DIP-26050N|ensemblmetazoa:F07A11.2a.1(transcript)|ensemblmetazoa:F07A11.2a.2(transcript)|ensemblmetazoa:F07A11.2a.3(transcript)|ensemblmetazoa:F07A11.2a.4(transcript)|ensemblmetazoa:WBGene00008546(gene)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490 ensemblmetazoa:F22B3.4.1(transcript)|ensemblmetazoa:F22B3.4.2(transcript)|ensemblmetazoa:WBGene00009035(gene)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|interpro:IPR035466|interpro:IPR035490|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR017932|refseq:NP_502156.1|wormbase:F22B3.4|reactome:R-CEL-446210|interpro:IPR029055 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:EXxUvmcQTTl6qV61gXGgFNAZHAo6239 rogid:LGYyHFF+9bf9MZIR4GEj8t79x686239 intact-crc:C998DAE06A66C78F|rigid:ZqARn4ICeWY4efVz4IC7J5lwGhk false sufficient binding region:280-725("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09496 uniprotkb:Q9N4E9 intact:EBI-2002622|ensemblmetazoa:C34C12.3.1 intact:EBI-331766|ensemblmetazoa:Y71H2B.3.1 psi-mi:ppp6_caeel(display_long)|uniprotkb:pph-6(gene name)|psi-mi:pph-6(display_short)|uniprotkb:Protein phosphatase pph-6(gene name synonym)|uniprotkb:C34C12.3(orf name) psi-mi:pp4rs_caeel(display_long)|uniprotkb:ppfr-4(gene name)|psi-mi:ppfr-4(display_short)|uniprotkb:Y71H2B.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459868|imex:IM-11985-420 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497714.2|wormbase:C34C12.3|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|ensemblmetazoa:C34C12.3.1(transcript)|ensemblmetazoa:WBGene00007922(gene)|go:"GO:0000235"(astral microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307" refseq:NP_497591.1|wormbase:Y71H2B.3|dip:DIP-27072N|ensemblmetazoa:WBGene00022193(gene)|ensemblmetazoa:Y71H2B.3.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oxbKzyo5Zjub6dw1D4AwrBXv1OM6239 rogid:DmlEnJ9TsnA4eRRlzusNPoTeDy46239 intact-crc:E063E830F20F653B|rigid:XsH8lwBsPmXw9w6EO2JxY53f/tA false sufficient binding region:28-194("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95Y13 uniprotkb:Q19130 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 intact:EBI-331451|ensemblmetazoa:F07A11.2a.1|ensemblmetazoa:F07A11.2a.2|ensemblmetazoa:F07A11.2a.3|ensemblmetazoa:F07A11.2a.4 psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:q19130_caeel(display_long)|uniprotkb:gfat-1(gene name)|psi-mi:gfat-1(display_short)|uniprotkb:CELE_F07A11.2(orf name)|uniprotkb:F07A11.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459898|imex:IM-11985-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N reactome:R-CEL-446210|refseq:NP_496480.1|wormbase:F07A11.2a|dip:DIP-26050N|ensemblmetazoa:F07A11.2a.1(transcript)|ensemblmetazoa:F07A11.2a.2(transcript)|ensemblmetazoa:F07A11.2a.3(transcript)|ensemblmetazoa:F07A11.2a.4(transcript)|ensemblmetazoa:WBGene00008546(gene)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 rogid:EXxUvmcQTTl6qV61gXGgFNAZHAo6239 intact-crc:9098B34524F926A4|rigid:0gJoYPhR1USZc8xa3jkRlfBKmWg false - sufficient binding region:280-725("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBE3 uniprotkb:Q9NES7 intact:EBI-2003873|ensemblmetazoa:F55F8.4.1|ensemblmetazoa:F55F8.4.2 intact:EBI-312701|ensemblmetazoa:Y39B6A.1.1 psi-mi:g5ebe3_caeel(display_long)|uniprotkb:cir-1(gene name)|psi-mi:cir-1(display_short)|uniprotkb:CELE_F55F8.4(orf name)|uniprotkb:F55F8.4(orf name) psi-mi:q9nes7_caeel(display_long)|uniprotkb:Y39B6A.1(orf name)|uniprotkb:CELE_Y39B6A.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459908|imex:IM-11985-424 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P91342(uniprot-removed-ac)|interpro:IPR040014|interpro:IPR019339|refseq:NP_491654.1|wormbase:F55F8.4|ensemblmetazoa:F55F8.4.1(transcript)|ensemblmetazoa:F55F8.4.2(transcript)|ensemblmetazoa:WBGene00018892(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048477"(oogenesis) refseq:NP_741698.1|wormbase:Y39B6A.1|ensemblmetazoa:WBGene00012664(gene)|ensemblmetazoa:Y39B6A.1.1(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|dip:DIP-25463N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WLmi45oz5gYwR5X4PaJ9/kUom1o6239 rogid:6zMeRngB/ofLajp54qhQGJW0o+86239 intact-crc:77EB121AB516C0ED|rigid:R4adF1nOdGeDZoxHRnCB0Dlnjd0 false - sufficient binding region:274-735("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFA2 uniprotkb:O45952 intact:EBI-328435|ensemblmetazoa:T27F2.3.1 intact:EBI-328477|ensemblmetazoa:Y48E1B.12.1 psi-mi:bir1_caeel(display_long)|uniprotkb:bir-1(gene name)|psi-mi:bir-1(display_short)|uniprotkb:Baculoviral IAP repeat-containing protein bir-1(gene name synonym)|uniprotkb:T27F2.3(orf name) psi-mi:csc1_caeel(display_long)|uniprotkb:csc-1(gene name)|psi-mi:csc-1(display_short)|uniprotkb:Y48E1B.12(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459918|imex:IM-11985-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22837(uniprot-removed-ac)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|refseq:NP_505949.1|ensemblmetazoa:T27F2.3.1(transcript)|ensemblmetazoa:WBGene00000249(gene)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016573"(histone acetylation)|go:"GO:0018991"(oviposition)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030496"(midbody)|wormbase:T27F2.3|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040039"(inductive cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) refseq:NP_496856.1|wormbase:Y48E1B.12|dip:DIP-26942N|ensemblmetazoa:WBGene00000804(gene)|ensemblmetazoa:Y48E1B.12.1(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990385"(meiotic spindle midzone)|go:"GO:1990386"(mitotic cleavage furrow ingression) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:UuKWa2EfGH/bNR+k86799sBFhrI6239 rogid:zNW8u6ujC+/4sR1rPWqVpKpuaPQ6239 intact-crc:402A36C8274B37FE|rigid:3PBGSNfeTWTeeawcGEuOPaHuSGo false - sufficient binding region:27-100("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P46769 uniprotkb:O45692 intact:EBI-313262|ensemblmetazoa:B0393.1.1|ensemblmetazoa:B0393.1.2 intact:EBI-6459928|ensemblmetazoa:M01E5.3a.1 psi-mi:rssa_caeel(display_long)|uniprotkb:B0393.1(orf name)|uniprotkb:rps-0(gene name)|psi-mi:rps-0(display_short) psi-mi:o45692_caeel(display_long)|uniprotkb:M01E5.3(orf name)|uniprotkb:CELE_M01E5.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459932|imex:IM-11985-426 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497978.1|wormbase:B0393.1|ensemblmetazoa:B0393.1.1(transcript)|ensemblmetazoa:B0393.1.2(transcript)|ensemblmetazoa:WBGene00004469(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975957|reactome:R-CEL-72649|reactome:R-CEL-975956|dip:DIP-26217N ensemblmetazoa:M01E5.3a.1(transcript)|ensemblmetazoa:WBGene00010806(gene)|refseq:NP_493335.1|wormbase:M01E5.3a|interpro:IPR018888 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:7tsgt7UcrNPsyTZQBzoRlcA/hvw6239 rogid:eCzuhTeqzNt5flhmwmwe01Fx0BA6239 intact-crc:6A27C3E4CE01AE02|rigid:Ju+ppElzOu5Q3tBqUHoH0hPubHA false - sufficient binding region:270-558("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:P34402 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459952|imex:IM-11985-428 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 intact-crc:5DC67D5A1C6B2B3C|rigid:QOzmWw2RbPJe2nS9iQbEB8o4BzE false - sufficient binding region:269-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21021 uniprotkb:O17915 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 intact:EBI-324099|ensemblmetazoa:K01G5.4.1 psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:ran_caeel(display_long)|uniprotkb:ran-1(gene name)|psi-mi:ran-1(display_short)|uniprotkb:K01G5.4(orf name)|uniprotkb:Ras-related nuclear protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459942|imex:IM-11985-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_499369.1|wormbase:K01G5.4|ensemblmetazoa:K01G5.4.1(transcript)|ensemblmetazoa:WBGene00004302(gene)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CEL-1655829|dip:DIP-25217N|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 rogid:yo75CoWqaTF5xYXAujyoTXXvRw86239 intact-crc:BDA6DEFFEC2F76FA|rigid:fyKnoNfHQd8QDN2YB9ieWLprel4 false sufficient binding region:269-860("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:Q9N359 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459972|imex:IM-11985-430 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 intact-crc:9055F7E39097907A|rigid:0eLA7ViUwOWZvFN8F1ykY4isBK0 false sufficient binding region:269-403("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91349 uniprotkb:G5EDL3 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 intact:EBI-324340|ensemblmetazoa:K07C11.2.1|ensemblmetazoa:K07C11.2.2 psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:g5edl3_caeel(display_long)|uniprotkb:AIR-1(gene name synonym)|uniprotkb:air-1(gene name)|psi-mi:air-1(display_short)|uniprotkb:K07C11.2(orf name)|uniprotkb:CELE_K07C11.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459962|imex:IM-11985-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N uniprotkb:Q21271(uniprot-removed-ac)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_505119.1|wormbase:K07C11.2|interpro:IPR030616|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0051233"(spindle midzone)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904781"(positive regulation of protein localization to centrosome)|ensemblmetazoa:K07C11.2.1(transcript)|ensemblmetazoa:K07C11.2.2(transcript)|ensemblmetazoa:WBGene00000098(gene)|go:"GO:0000235"(astral microtubule) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rogid:WWa/rjtXe6RruL7Ui72IJ5OJXxw6239 intact-crc:73BDC1EA2774BA6F|rigid:Vdh+WPxj7Qz3RQkueKZwxa14L3M false sufficient binding region:269-470("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91870 uniprotkb:P91349 intact:EBI-320962|ensemblmetazoa:F32H2.3.1|ensemblmetazoa:F32H2.3.2 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 psi-mi:spd2_caeel(display_long)|uniprotkb:F32H2.3(orf name)|uniprotkb:spd-2(gene name)|psi-mi:spd-2(display_short) psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459982|imex:IM-11985-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492414.1|wormbase:F32H2.3|ensemblmetazoa:F32H2.3.1(transcript)|ensemblmetazoa:F32H2.3.2(transcript)|ensemblmetazoa:WBGene00004953(gene)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019901"(protein kinase binding)|go:"GO:0040025"(vulval development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR039103|dip:DIP-25500N refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:GBGtZRHVbrFLFhWQy/m9+L17Etk6239 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 intact-crc:84AD5B4FF0E71281|rigid:szpeIV+G7aEvZvL4C+Vz006YE4U false - sufficient binding region:269-336("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:Q9BL83 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-2005777|ensemblmetazoa:Y34D9A.10.1 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:q9bl83_caeel(display_long)|uniprotkb:vps-4(gene name)|psi-mi:vps-4(display_short)|uniprotkb:CELE_Y34D9A.10(orf name)|uniprotkb:Y34D9A.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6459992|imex:IM-11985-432 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_490816.4|wormbase:Y34D9A.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|interpro:IPR036181|reactome:R-CEL-9668328|interpro:IPR031255|ensemblmetazoa:WBGene00021334(gene)|ensemblmetazoa:Y34D9A.10.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007033"(vacuole organization)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0016197"(endosomal transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903539"(protein localization to postsynaptic membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:b93R1ndEtzzHaOF6Gv3G7NwLxAw6239 intact-crc:3509C457C343DADD|rigid:5ylZYs2wYAddVEygqS2qzU5TNao false sufficient binding region:269-335("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:Q95XZ0 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-2006014|uniprotkb:Q3V5K1|uniprotkb:Q95XY9|ensemblmetazoa:Y51H7C.6a.1 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:cog4_caeel(display_long)|uniprotkb:cogc-4(gene name)|psi-mi:cogc-4(display_short)|uniprotkb:Component of oligomeric Golgi complex 4(gene name synonym)|uniprotkb:Y51H7C.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460012|imex:IM-11985-434 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 refseq:NP_001033341.1|refseq:NP_493966.1|refseq:NP_493967.1|wormbase:Y51H7C.6a|wormbase:Y51H7C.6b|wormbase:Y51H7C.6c|interpro:IPR013167(COG4 transport)|reactome:R-CEL-6807878|reactome:R-CEL-6811438|ensemblmetazoa:WBGene00021784(gene)|ensemblmetazoa:Y51H7C.6a.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0048213"(Golgi vesicle prefusion complex stabilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:BBSGzEvj00FcUTtxYSfPSg6jNHQ6239 intact-crc:8CF14F82D946B131|rigid:vHtWS8FIo/9sbEKUqililRVafhA false - sufficient binding region:265-336("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N359 uniprotkb:Q17796 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460002|imex:IM-11985-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 intact-crc:0EAEB8B3C4B257F1|rigid:FodHfVSN/CPpLVAi8QH77FOrEvA false - sufficient binding region:265-467("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2006534 uniprotkb:Q9N4A7-1 - intact:EBI-6456140|ensemblmetazoa:Y77E11A.13a.1 psi-mi:h2l061_caeel(display_short)|psi-mi:EBI-2006534(display_long)|uniprotkb:F49E10.4(orf name)|uniprotkb:CELE_F49E10.4(orf name) psi-mi:q9n4a7-1(display_long)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:Nuclear pore complex protein 20(gene name synonym)|uniprotkb:npp-20(gene name)|psi-mi:npp-20(display_short)|uniprotkb:CeSec13R(gene name synonym)|uniprotkb:sec-13(gene name synonym)|uniprotkb:Y77E11A.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460037|imex:IM-11985-436 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:H2L061(uniprot-removed-ac) intact:EBI-318290(isoform-parent)|ensemblmetazoa:WBGene00003806(gene)|ensemblmetazoa:Y77E11A.13a.1(transcript) psi-mi:"MI:0469"(intact) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5zoVNh1qhQGUcToSOiD62nV6S7g6239 rogid:ZKmmnaa7DFkQzBBKNad56Ic7GvI6239 intact-crc:65C2342F18066095|rigid:LKdec4xt8nv+feQBucmjBoPAzZ0 false sufficient binding region:2-645("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:P10567 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-318168|uniprotkb:Q93214|uniprotkb:Q93439|ensemblmetazoa:F07A5.7a.1|ensemblmetazoa:F07A5.7a.2|ensemblmetazoa:F07A5.7a.3|ensemblmetazoa:F07A5.7a.4|intact:EBI-11465138|intact:EBI-11466975|intact:EBI-6460025|uniprotkb:B3WFV3 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:mysp_caeel(display_long)|uniprotkb:unc-15(gene name)|psi-mi:unc-15(display_short)|uniprotkb:F07A5.7(orf name)|uniprotkb:Uncoordinated protein 15(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460022|imex:IM-11985-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 refseq:NP_492085.1|wormbase:F07A5.7a|ensemblmetazoa:F07A5.7a.1(transcript)|ensemblmetazoa:F07A5.7a.2(transcript)|ensemblmetazoa:F07A5.7a.3(transcript)|ensemblmetazoa:F07A5.7a.4(transcript)|ensemblmetazoa:WBGene00006754(gene)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016459"(myosin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032982"(myosin filament)|go:"GO:0040011"(locomotion)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060279"(positive regulation of ovulation)|go:"GO:0060298"(positive regulation of sarcomere organization)|interpro:IPR002928(Myosin tail)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:NP_001129763.1|wormbase:F07A5.7b|dip:DIP-24443N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/02/23 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:qDSWRA42Ad8ZvgnKN1TomAfe1f46239 intact-crc:9491DAA6A456B3EC|rigid:QUOARCzd90UdwpUtUVSBn2FQrvM false - sufficient binding region:583-872("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ED95 uniprotkb:G5EDR3 intact:EBI-2003295|ensemblmetazoa:Y105E8A.19.1 intact:EBI-2003301|ensemblmetazoa:F26E4.1.1 psi-mi:g5ed95_caeel(display_long)|uniprotkb:yars-1(gene name)|psi-mi:yars-1(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:yrs-2(gene name synonym)|uniprotkb:CELE_Y105E8A.19(orf name)|uniprotkb:Y105E8A.19(orf name) psi-mi:2ab1_caeel(display_long)|uniprotkb:sur-6(gene name)|psi-mi:sur-6(display_short)|uniprotkb:Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit sur-6(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B sur-6(gene name synonym)|uniprotkb:F26E4.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460047|imex:IM-11985-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8WQA5(uniprot-removed-ac)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|refseq:NP_740947.2|wormbase:Y105E8A.19|ensemblmetazoa:WBGene00013677(gene)|ensemblmetazoa:Y105E8A.19.1(transcript)|go:"GO:0004831"(tyrosine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006437"(tyrosyl-tRNA aminoacylation) uniprotkb:P90851(uniprot-removed-ac)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_492591.1|wormbase:F26E4.1|reactome:R-CEL-69231|reactome:R-CEL-2995383|reactome:R-CEL-69273|interpro:IPR036322|reactome:R-CEL-975957|ensemblmetazoa:F26E4.1.1(transcript)|ensemblmetazoa:WBGene00006352(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0002119"(nematode larval development)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0070262"(peptidyl-serine dephosphorylation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b7w4s9qLVw3EPe5vH/pGX/pddyQ6239 rogid:vgojL7SRpj6x34AcKSzU5qCBHIs6239 intact-crc:B38F07B4DE980EE3|rigid:99Qcme7xNJ9rUKYLJDNx44kfjyU false sufficient binding region:264-334("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4I1 intact:EBI-6460057 intact:EBI-6460061|ensemblmetazoa:Y71F9AL.14.1|ensemblmetazoa:Y71F9AL.14.2 - psi-mi:q9n4i1_caeel(display_long)|uniprotkb:Y71F9AL.14(orf name)|uniprotkb:dnc-5(gene name)|psi-mi:dnc-5(display_short)|uniprotkb:CELE_Y71F9AL.14(orf name) psi-mi:q86nb8_caeel(display_short)|psi-mi:EBI-6460057(display_long)|uniprotkb:trak-1(gene name)|psi-mi:trak-1(display_short)|uniprotkb:CELE_T27A3.1(orf name)|uniprotkb:T27A3.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460066|imex:IM-11985-438 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022118(gene)|ensemblmetazoa:Y71F9AL.14.1(transcript)|ensemblmetazoa:Y71F9AL.14.2(transcript)|go:"GO:0005869"(dynactin complex)|reactome:R-CEL-3371497|reactome:R-CEL-6811436|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|refseq:NP_491065.1|wormbase:Y71F9AL.14|reactome:R-CEL-6807878 uniprotkb:Q86NB8(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gqzEMyE/hsdUPrCRO3WjD3HIYqY6239 rogid:fa2e1ObnTiUR07ptWNR9vrZ1Upw6239 intact-crc:8F3EE54524A1DF18|rigid:xmYmxLC/RrJv7kDHIy4CmsYrt3E false - sufficient binding region:263-532("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18688 uniprotkb:O02108 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 intact:EBI-329675|ensemblmetazoa:W08F4.8a.1 psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:cdc37_caeel(display_long)|uniprotkb:W08F4.8(orf name)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:Cell division cycle-related protein 37(gene name synonym)|uniprotkb:cdc-37(gene name)|psi-mi:cdc-37(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460076|imex:IM-11985-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 refseq:NP_001040820.1|wormbase:W08F4.8a|reactome:R-CEL-114608|dip:DIP-25193N|ensemblmetazoa:W08F4.8a.1(transcript)|ensemblmetazoa:WBGene00021097(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|reactome:R-CEL-8863795|reactome:R-CEL-9652282|reactome:R-CEL-5675482 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 rogid:BGPUAjBwpp1jT1o4miWT7nTRwus6239 intact-crc:4AAD2F3D2F4BC3FC|rigid:mUsCyoZU7m0AyJt8JpHw3nUa5R0 false sufficient binding region:262-702("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44158 uniprotkb:O76258 intact:EBI-2002164|ensemblmetazoa:CD4.4.1 intact:EBI-2002148|ensemblmetazoa:C09G12.9.1 psi-mi:o44158_caeel(display_long)|uniprotkb:vps-37(gene name)|psi-mi:vps-37(display_short)|uniprotkb:CELE_CD4.4(orf name)|uniprotkb:CD4.4(orf name) psi-mi:o76258_caeel(display_long)|uniprotkb:tsg-101(gene name)|psi-mi:tsg-101(display_short)|uniprotkb:CELE_C09G12.9(orf name)|uniprotkb:C09G12.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460086|imex:IM-11985-440 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504474.1|wormbase:CD4.4|interpro:IPR009851(Modifier of rudimentary, Modr)|reactome:R-CEL-917729|ensemblmetazoa:CD4.4.1(transcript)|ensemblmetazoa:WBGene00016990(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle) refseq:NP_500364.2|wormbase:C09G12.9|interpro:IPR017916|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR008883(Tumour susceptibility gene 101)|reactome:R-CEL-917729|interpro:IPR037202|ensemblmetazoa:C09G12.9.1(transcript)|ensemblmetazoa:WBGene00015658(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:m90qSpq0IrJ5wX87NxFC8W5DuiE6239 rogid:tAhzbKmVoJZA+IwR6RLdGgDFIYI6239 intact-crc:9484CA824344D3F3|rigid:bK73HSkmVj7iDD/9SvK85KWNKDg false sufficient binding region:26-166("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02217 uniprotkb:Q21443 intact:EBI-1187455|uniprotkb:A5Z2U4|ensemblmetazoa:C25A1.9a.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:p2r31_caeel(display_long)|uniprotkb:rsa-1(gene name)|psi-mi:rsa-1(display_short)|uniprotkb:Regulator of spindle assembly protein 1(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A 72kDa regulatory subunit rsa-1(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A regulatory subunit B'' rsa-1(gene name synonym)|uniprotkb:C25A1.9(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460096|imex:IM-11985-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492683.1|wormbase:C25A1.9a|interpro:IPR011992(EF-Hand type)|refseq:NP_001122424.1|wormbase:C25A1.9b|ensemblmetazoa:C25A1.9a.1(transcript)|ensemblmetazoa:WBGene00007710(gene)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR028846 reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:TzkShn9bEdl1tOgz8nIXnAHZar86239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:962A85271D2E8D35|rigid:0OTI3518Q4fByDujmn7oAkzODQo false - sufficient binding region:251-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WQC0-3 uniprotkb:Q21443 intact:EBI-6459543|ensemblmetazoa:F56B6.2b.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:q8wqc0-3(display_long)|uniprotkb:Protein C2-RGS(gene name synonym)|uniprotkb:Regulator of G-protein signaling c2(gene name synonym)|uniprotkb:F56B6.2(orf name)|uniprotkb:rgs-7(gene name)|psi-mi:rgs-7(display_short) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460116|imex:IM-11985-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F56B6.2b.1(transcript)|ensemblmetazoa:WBGene00004350(gene)|intact:EBI-6499941(isoform-parent) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b5aipypkEQmIRlZRHwWc393n5gE6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:C1EF39AE62B93934|rigid:nu55Brvb0uDhHIUj+W23M9QIY3Y false - sufficient binding region:251-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39745-1 uniprotkb:Q21443 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460106|imex:IM-11985-442 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:C3569AE4A38207ED|rigid:4zqHFwP4kAUbx7C8XEQ7baP53fk false - sufficient binding region:251-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N583 uniprotkb:Q21443 intact:EBI-6460139|ensemblmetazoa:Y110A7A.1a.1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:q9n583_caeel(display_long)|uniprotkb:Y110A7A.1(orf name)|uniprotkb:hcp-6(gene name)|psi-mi:hcp-6(display_short)|uniprotkb:CELE_Y110A7A.1(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460136|imex:IM-11985-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00001833(gene)|ensemblmetazoa:Y110A7A.1a.1(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|interpro:IPR032682|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|refseq:NP_491538.1|wormbase:Y110A7A.1a reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:6XJTxRVObmAgWGAU+HeI/cVukGA6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:D68212DBA37C015E|rigid:KtwCMegvg1qZ1BxfEru8KZUPZbY false - sufficient binding region:251-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:Q09601-1 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460126|imex:IM-11985-444 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:167440AD60706040|rigid:GlOF77jtMuQ9EUgKjmiur0jaUiw false sufficient binding region:251-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XZ0 uniprotkb:G5ECG0 intact:EBI-2006014|uniprotkb:Q3V5K1|uniprotkb:Q95XY9|ensemblmetazoa:Y51H7C.6a.1 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:cog4_caeel(display_long)|uniprotkb:cogc-4(gene name)|psi-mi:cogc-4(display_short)|uniprotkb:Component of oligomeric Golgi complex 4(gene name synonym)|uniprotkb:Y51H7C.6(orf name) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460152|imex:IM-11985-446 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001033341.1|refseq:NP_493966.1|refseq:NP_493967.1|wormbase:Y51H7C.6a|wormbase:Y51H7C.6b|wormbase:Y51H7C.6c|interpro:IPR013167(COG4 transport)|reactome:R-CEL-6807878|reactome:R-CEL-6811438|ensemblmetazoa:WBGene00021784(gene)|ensemblmetazoa:Y51H7C.6a.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0048213"(Golgi vesicle prefusion complex stabilization) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BBSGzEvj00FcUTtxYSfPSg6jNHQ6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:6809DC68B36E5D8E|rigid:vHtWS8FIo/9sbEKUqililRVafhA false sufficient binding region:251-401("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QC4 uniprotkb:Q9U211 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 intact:EBI-2007135|ensemblmetazoa:Y57A10A.24.1 psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:q9u211_caeel(display_long)|uniprotkb:Y57A10A.24(orf name)|uniprotkb:CELE_Y57A10A.24(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460162|imex:IM-11985-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 interpro:IPR028150|interpro:IPR006150(Cysteine-rich repeat)|refseq:NP_496600.1|wormbase:Y57A10A.24|ensemblmetazoa:WBGene00013264(gene)|ensemblmetazoa:Y57A10A.24.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2020/10/21 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 rogid:ZBbJ2GCxVJObSqDS3iHFaNXFcOY6239 intact-crc:3D874000C288E1A3|rigid:bE8RraXXCLvNC+S+rMIxFVX1ARQ false - sufficient binding region:237-387("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53016 uniprotkb:Q18547 intact:EBI-318155|ensemblmetazoa:F31E3.3.1 intact:EBI-314981|ensemblmetazoa:C39E9.13.1 psi-mi:rfc4_caeel(display_long)|uniprotkb:F31E3.3(orf name)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:rfc-4(gene name)|psi-mi:rfc-4(display_short) psi-mi:q18547_caeel(display_long)|uniprotkb:rfc-3(gene name)|psi-mi:rfc-3(display_short)|uniprotkb:CELE_C39E9.13(orf name)|uniprotkb:C39E9.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460172|imex:IM-11985-448 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498521.1|wormbase:F31E3.3|ensemblmetazoa:F31E3.3.1(transcript)|ensemblmetazoa:WBGene00004340(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|dip:DIP-24293N|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-110320|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-69091 refseq:NP_502517.1|wormbase:C39E9.13|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-110320|reactome:R-CEL-69091|ensemblmetazoa:C39E9.13.1(transcript)|ensemblmetazoa:WBGene00004339(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|go:"GO:0005663"(DNA replication factor C complex)|dip:DIP-27479N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:17GeJI7eKmB2+zqvOLntNT/n4eo6239 rogid:9i4qy+nQFgxA2CsSmCxrFmzOsfM6239 intact-crc:917D9D7080217FBC|rigid:YbSPT11jLj2rOo/eocr3k8kMTHk false - sufficient binding region:251-354("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q966L6 uniprotkb:P52819-1 intact:EBI-2002434|ensemblmetazoa:E01A2.4.1|ensemblmetazoa:E01A2.4.2 intact:EBI-6460185|ensemblmetazoa:C27A2.2a.1 psi-mi:q966l6_caeel(display_long)|uniprotkb:let-504(gene name)|psi-mi:let-504(display_short)|uniprotkb:E01A2.4(orf name)|uniprotkb:CELE_E01A2.4(orf name) psi-mi:p52819-1(display_long)|uniprotkb:C27A2.2(orf name)|uniprotkb:rpl-22(gene name)|psi-mi:rpl-22(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460182|imex:IM-11985-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009269(Protein of unknown function DUF926)|refseq:NP_491301.1|wormbase:E01A2.4|interpro:IPR040466|ensemblmetazoa:E01A2.4.1(transcript)|ensemblmetazoa:E01A2.4.2(transcript)|ensemblmetazoa:WBGene00002696(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010468"(regulation of gene expression) ensemblmetazoa:WBGene00004434(gene)|ensemblmetazoa:C27A2.2a.1(transcript)|intact:EBI-6499999(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:uFgJEqUfLjbmqnMplarxE6vk+Ck6239 rogid:1tO8rcN2pN09gdo5weBdI9o2fVQ6239 intact-crc:8A38F8B6D494D39E|rigid:2uuCYSzXCa7g4RYBqRuf8KLPh5k false sufficient binding region:251-353("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVP0 uniprotkb:Q9U211 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 intact:EBI-2007135|ensemblmetazoa:Y57A10A.24.1 psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:q9u211_caeel(display_long)|uniprotkb:Y57A10A.24(orf name)|uniprotkb:CELE_Y57A10A.24(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460207|imex:IM-11985-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) interpro:IPR028150|interpro:IPR006150(Cysteine-rich repeat)|refseq:NP_496600.1|wormbase:Y57A10A.24|ensemblmetazoa:WBGene00013264(gene)|ensemblmetazoa:Y57A10A.24.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2020/10/21 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 rogid:ZBbJ2GCxVJObSqDS3iHFaNXFcOY6239 intact-crc:AA2EE43A3EA9552B|rigid:j/zLj8bFzcvjPK6q8Y9UGfyvHZc false - sufficient binding region:237-287("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76258 uniprotkb:O44158 intact:EBI-2002148|ensemblmetazoa:C09G12.9.1 intact:EBI-2002164|ensemblmetazoa:CD4.4.1 psi-mi:o76258_caeel(display_long)|uniprotkb:tsg-101(gene name)|psi-mi:tsg-101(display_short)|uniprotkb:CELE_C09G12.9(orf name)|uniprotkb:C09G12.9(orf name) psi-mi:o44158_caeel(display_long)|uniprotkb:vps-37(gene name)|psi-mi:vps-37(display_short)|uniprotkb:CELE_CD4.4(orf name)|uniprotkb:CD4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460197|imex:IM-11985-450 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500364.2|wormbase:C09G12.9|interpro:IPR017916|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR008883(Tumour susceptibility gene 101)|reactome:R-CEL-917729|interpro:IPR037202|ensemblmetazoa:C09G12.9.1(transcript)|ensemblmetazoa:WBGene00015658(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process) refseq:NP_504474.1|wormbase:CD4.4|interpro:IPR009851(Modifier of rudimentary, Modr)|reactome:R-CEL-917729|ensemblmetazoa:CD4.4.1(transcript)|ensemblmetazoa:WBGene00016990(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tAhzbKmVoJZA+IwR6RLdGgDFIYI6239 rogid:m90qSpq0IrJ5wX87NxFC8W5DuiE6239 intact-crc:D476A27D3D315C4C|rigid:bK73HSkmVj7iDD/9SvK85KWNKDg false sufficient binding region:251-301("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01422 uniprotkb:Q9GS00 intact:EBI-331413|ensemblmetazoa:B0025.2.1|ensemblmetazoa:B0025.2.2 intact:EBI-331408|ensemblmetazoa:Y59A8A.1.1 psi-mi:csn2_caeel(display_long)|uniprotkb:B0025.2(orf name)|uniprotkb:csn-2(gene name)|psi-mi:csn-2(display_short) psi-mi:csn1_caeel(display_long)|uniprotkb:Y59A8A.1(orf name)|uniprotkb:csn-1(gene name)|psi-mi:csn-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460227|imex:IM-11985-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491740.1|wormbase:B0025.2|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-24665N|ensemblmetazoa:B0025.2.1(transcript)|ensemblmetazoa:B0025.2.2(transcript)|ensemblmetazoa:WBGene00000814(gene)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|reactome:R-CEL-5696394 refseq:NP_507507.1|wormbase:Y59A8A.1|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-26112N|ensemblmetazoa:WBGene00000813(gene)|ensemblmetazoa:Y59A8A.1.1(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR019585|interpro:IPR033008|interpro:IPR036390|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:qwX/mKYLxZitZLkfNa3RPYDLYyo6239 rogid:OpmKXZHWN+haPePSg+liDfvUe4E6239 intact-crc:A205C70E9C3E2B1A|rigid:h7q8Jme1WseWqR231porjDgi5v8 false - sufficient binding region:244-601("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19286 uniprotkb:Q95XR0 intact:EBI-320062|uniprotkb:Q21064|uniprotkb:Q95QM2|ensemblmetazoa:F10C1.7a.1 intact:EBI-314404|ensemblmetazoa:Y39G10AR.8.1 psi-mi:ifb2_caeel(display_long)|uniprotkb:ifb-2(gene name)|psi-mi:ifb-2(display_short)|uniprotkb:F10C1.7(orf name)|uniprotkb:Intermediate filament protein B2(gene name synonym)|uniprotkb:Cel IF B2(gene name synonym) psi-mi:q95xr0_caeel(display_long)|uniprotkb:eif-2gamma(gene name)|psi-mi:eif-2gamma(display_short)|uniprotkb:CELE_Y39G10AR.8(orf name)|uniprotkb:Y39G10AR.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460217|imex:IM-11985-452 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495133.1|refseq:NP_495134.1|wormbase:F10C1.7a|wormbase:F10C1.7c|ensemblmetazoa:F10C1.7a.1(transcript)|ensemblmetazoa:WBGene00002054(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0030054"(cell junction)|go:"GO:0045179"(apical cortex)|go:"GO:1990357"(terminal web)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-26763N ensemblmetazoa:WBGene00021466(gene)|ensemblmetazoa:Y39G10AR.8.1(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|refseq:NP_490960.1|wormbase:Y39G10AR.8|reactome:R-CEL-156827|reactome:R-CEL-382556|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-72731|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128|reactome:R-CEL-72649|dip:DIP-24612N|reactome:R-CEL-381042 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:SIkUfQ59iJC29JoQFWYxCZdKiv86239 rogid:cy5oFiBGBh12/QymfVTuf21UAIk6239 intact-crc:EF3D34C84ED368B0|rigid:hamJDY6VnXFeMFv6HlSL+BEUL1I false sufficient binding region:248-543("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O18246 uniprotkb:P53016 intact:EBI-317099|ensemblmetazoa:Y57G11C.22a.1 intact:EBI-318155|ensemblmetazoa:F31E3.3.1 psi-mi:o18246_caeel(display_long)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:CELE_Y57G11C.22(orf name)|uniprotkb:Y57G11C.22(orf name) psi-mi:rfc4_caeel(display_long)|uniprotkb:F31E3.3(orf name)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:rfc-4(gene name)|psi-mi:rfc-4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460237|imex:IM-11985-454 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041046.1|wormbase:Y57G11C.22a|ensemblmetazoa:WBGene00013317(gene)|ensemblmetazoa:Y57G11C.22a.1(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-27078N refseq:NP_498521.1|wormbase:F31E3.3|ensemblmetazoa:F31E3.3.1(transcript)|ensemblmetazoa:WBGene00004340(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|dip:DIP-24293N|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-110320|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-69091 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:EwNg/0sCGH1I5xMzixpfij4S4Gk6239 rogid:17GeJI7eKmB2+zqvOLntNT/n4eo6239 intact-crc:E90C6A0A0B9FEF41|rigid:wbUkA+3fwkAwsG43RrrlpPlXdPo false sufficient binding region:2-444("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6460247 uniprotkb:P91457 intact:EBI-6306345 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:ebi6306345(display_short)|psi-mi:EBI-6460247(display_long)|intact:C17E4.2(author assigned name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460251|imex:IM-11985-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:FEB1921918877F96 false sufficient binding region:2-444("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EE07 uniprotkb:O01488 intact:EBI-329476|ensemblmetazoa:R74.3b.1 intact:EBI-320537|ensemblmetazoa:C13F10.2.1 psi-mi:g5ee07_caeel(display_long)|uniprotkb:xbp-1(gene name)|psi-mi:xbp-1(display_short)|uniprotkb:R74.3(orf name)|uniprotkb:CELE_R74.3(orf name) psi-mi:o01488_caeel(display_long)|uniprotkb:kxd-1(gene name)|psi-mi:kxd-1(display_short)|uniprotkb:C13F10.2(orf name)|uniprotkb:CELE_C13F10.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460261|imex:IM-11985-456 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8WRF1(uniprot-removed-ac)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|refseq:NP_001076646.1|wormbase:R74.3|ensemblmetazoa:R74.3b.1(transcript)|ensemblmetazoa:WBGene00006959(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response) refseq:NP_504831.1|wormbase:C13F10.2|ensemblmetazoa:C13F10.2.1(transcript)|ensemblmetazoa:WBGene00015742(gene)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|dip:DIP-27148N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:TIdIllD7KrmvBVi54fMg9HXkANM6239 rogid:ZX/rck9tSHblPGJKegKAjZiqxeA6239 intact-crc:EAF252FD4206A09C|rigid:EqMJAWvyIbQHIyWYzFOgoQ+an5g false sufficient binding region:24-287("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFV3 uniprotkb:Q9GRY9 intact:EBI-1187461|intact:EBI-1187509|uniprotkb:G5EDA1|ensemblmetazoa:Y48A6B.11b.1 intact:EBI-320508|ensemblmetazoa:Y59A8B.10a.1|ensemblmetazoa:Y59A8B.10a.2|ensemblmetazoa:Y59A8B.10a.3 psi-mi:rsa2_caeel(display_long)|uniprotkb:Y48A6B.11(orf name)|uniprotkb:rsa-2(gene name)|psi-mi:rsa-2(display_short) psi-mi:q9gry9_caeel(display_long)|uniprotkb:nova-1(gene name)|psi-mi:nova-1(display_short)|uniprotkb:CELE_Y59A8B.10(orf name)|uniprotkb:Y59A8B.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460271|imex:IM-11985-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7YSJ2(uniprot-removed-ac)|refseq:NP_001022887.1|wormbase:Y48A6B.11b|wormbase:Y48A6B.11a|refseq:NP_001022886.1|ensemblmetazoa:WBGene00012972(gene)|ensemblmetazoa:Y48A6B.11b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0048566"(embryonic digestive tract development) wormbase:Y59A8B.10a|ensemblmetazoa:WBGene00013347(gene)|ensemblmetazoa:Y59A8B.10a.1(transcript)|ensemblmetazoa:Y59A8B.10a.2(transcript)|ensemblmetazoa:Y59A8B.10a.3(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|refseq:NP_001256769.1|dip:DIP-24651N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2016/09/27 rogid:7PBwPJFROCL8Mv1INcviVzZGFCE6239 rogid:gInq7hxk90pbcpjxNwzmjqwdm+U6239 intact-crc:009991E3132677A0|rigid:Tp0wgDrqHtj9/VAwNRil7VAiNQc false - sufficient binding region:2-413("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90925 uniprotkb:Q09601-1 intact:EBI-318020|ensemblmetazoa:K08F8.4a.1|uniprotkb:I2HA98|uniprotkb:Q9XYQ5 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:ph4h_caeel(display_long)|uniprotkb:pah-1(gene name)|psi-mi:pah-1(display_short)|uniprotkb:Phe-4-monooxygenase(gene name synonym)|uniprotkb:Biogenic amine synthesis protein 2(gene name synonym)|uniprotkb:K08F8.4(orf name)|uniprotkb:bas-2(gene name synonym)|uniprotkb:Tryptophan 5-monooxygenase(gene name synonym) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460291|imex:IM-11985-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:K08F8.4a|refseq:NP_001254185.1|ensemblmetazoa:K08F8.4a.1(transcript)|ensemblmetazoa:WBGene00000240(gene)|go:"GO:0000003"(reproduction)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0004510"(tryptophan 5-monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006559"(L-phenylalanine catabolic process)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0006571"(tyrosine biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0040002"(collagen and cuticulin-based cuticle development)|go:"GO:0042438"(melanin biosynthetic process)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR005961(Phenylalanine-4-hydroxylase, tetrameric form)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR036329|interpro:IPR036951|interpro:IPR041912|dip:DIP-25264N|refseq:NP_001254184.1|wormbase:K08F8.4b|reactome:R-CEL-8964208 intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Ceg0vwDFmdjAryQGSjHA7yBFPXc6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:D94F88AA08EE5459|rigid:BQZWAIyWSgmoNOqgasGpxBD6XiI false sufficient binding region:23-457("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4I1 uniprotkb:V6CJ04 intact:EBI-6460061|ensemblmetazoa:Y71F9AL.14.1|ensemblmetazoa:Y71F9AL.14.2 intact:EBI-2006416|uniprotkb:V6CK55|ensemblmetazoa:C43G2.2a.1 psi-mi:q9n4i1_caeel(display_long)|uniprotkb:Y71F9AL.14(orf name)|uniprotkb:dnc-5(gene name)|psi-mi:dnc-5(display_short)|uniprotkb:CELE_Y71F9AL.14(orf name) psi-mi:bicd_caeel(display_long)|uniprotkb:bicd-1(gene name)|psi-mi:bicd-1(display_short)|uniprotkb:C43G2.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460281|imex:IM-11985-458 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00022118(gene)|ensemblmetazoa:Y71F9AL.14.1(transcript)|ensemblmetazoa:Y71F9AL.14.2(transcript)|go:"GO:0005869"(dynactin complex)|reactome:R-CEL-3371497|reactome:R-CEL-6811436|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR011004(Trimeric LpxA-like)|refseq:NP_491065.1|wormbase:Y71F9AL.14|reactome:R-CEL-6807878 refseq:NP_001293734.1|reactome:R-CEL-6811436|refseq:NP_001293735.1|wormbase:C43G2.2a|interpro:IPR018477|wormbase:C43G2.2b|ensemblmetazoa:C43G2.2a.1(transcript)|ensemblmetazoa:WBGene00016611(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0030425"(dendrite)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034452"(dynactin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gqzEMyE/hsdUPrCRO3WjD3HIYqY6239 rogid:GKxa/6aMKacxpHsFwY9PqHjwIBw6239 intact-crc:DA4B56F520F2DF3D|rigid:eh/ildlXqmTyylrJ0Unw27l7RAY false - sufficient binding region:235-737("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BKS1 uniprotkb:G5ECR7 intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1 intact:EBI-330567|ensemblmetazoa:Y41C4A.10.1 psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name) psi-mi:g5ecr7_caeel(display_long)|uniprotkb:3L686(gene name synonym)|uniprotkb:elb-1(gene name)|psi-mi:elb-1(display_short)|uniprotkb:Y41C4A.10(orf name)|uniprotkb:CELE_Y41C4A.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460301|imex:IM-11985-460 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N uniprotkb:Q9XWU4(uniprot-removed-ac)|refseq:NP_499517.1|reactome:R-CEL-674695|reactome:R-CEL-6796648|wormbase:Y41C4A.10|interpro:IPR039049|interpro:IPR029071|reactome:R-CEL-1234176|reactome:R-CEL-983168|reactome:R-CEL-8951664|ensemblmetazoa:WBGene00001235(gene)|ensemblmetazoa:Y41C4A.10.1(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|reactome:R-CEL-75955|reactome:R-CEL-112382 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239 rogid:nd6q1xH1t5OIdfLT3hHtTS3gTqU6239 intact-crc:DB6E6F1E887DD103|rigid:5RYNpxrxzTZrh9A5wAfdEXUt04I false sufficient binding region:23-124("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09350 uniprotkb:Q09543 intact:EBI-329497|ensemblmetazoa:T09B9.4.1 intact:EBI-322806|ensemblmetazoa:F48E8.5.1|ensemblmetazoa:F48E8.5.2 psi-mi:yru4_caeel(display_long)|uniprotkb:T09B9.4(orf name) psi-mi:2aaa_caeel(display_long)|uniprotkb:F48E8.5(orf name)|uniprotkb:Protein phosphatase PP2A regulatory subunit A(gene name synonym)|uniprotkb:paa-1(gene name)|psi-mi:paa-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460311|imex:IM-11985-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_509640.1|wormbase:T09B9.4|dip:DIP-24984N|ensemblmetazoa:T09B9.4.1(transcript)|ensemblmetazoa:WBGene00011645(gene)|interpro:IPR019152 refseq:NP_498162.2|wormbase:F48E8.5|reactome:R-CEL-69231|reactome:R-CEL-198753|reactome:R-CEL-202670|reactome:R-CEL-2995383|reactome:R-CEL-69273|ensemblmetazoa:F48E8.5.1(transcript)|ensemblmetazoa:F48E8.5.2(transcript)|ensemblmetazoa:WBGene00003901(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043186"(P granule)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|reactome:R-CEL-195253|dip:DIP-26927N|reactome:R-CEL-196299|reactome:R-CEL-975957|reactome:R-CEL-5673000|reactome:R-CEL-5675221|reactome:R-CEL-389513|reactome:R-CEL-6811558 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:lyVJRX33hq3s3To7ReiGfruWG1Y6239 rogid:9aApJ05VzQgGuaJ65kMPqQRBEb06239 intact-crc:591F88CE4854723C|rigid:BL4PUGf9xeT0yVEiX3LilOy/rSE false sufficient binding region:229-528("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-2004276 uniprotkb:Q23670 - intact:EBI-323996|uniprotkb:Q27509|ensemblmetazoa:K12D12.1.1 psi-mi:q3v5h2_caeel(display_short)|psi-mi:EBI-2004276(display_long)|uniprotkb:CELE_Y66H1B.2(orf name)|uniprotkb:fln-1(gene name)|psi-mi:fln-1(display_short) psi-mi:top2_caeel(display_long)|uniprotkb:top-2(gene name)|psi-mi:top-2(display_short)|uniprotkb:DNA topoisomerase II(gene name synonym)|uniprotkb:K12D12.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460321|imex:IM-11985-462 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3V5H2(uniprot-removed-ac) refseq:NP_496536.1|wormbase:K12D12.1|ensemblmetazoa:K12D12.1.1(transcript)|ensemblmetazoa:WBGene00010785(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006265"(DNA topological change)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR034157|interpro:IPR036890|interpro:IPR031660|reactome:R-CEL-4615885|dip:DIP-27416N psi-mi:"MI:0469"(intact) no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:c/ZnMLd+xHN4cnDLE38h09cLZWY6239 rogid:mMVe6/tBKCkNlRfJ3X08lsDKthg6239 intact-crc:03B017E04C6FC682|rigid:AfCxDvDxd48TFEFBj54SuychZ7A false sufficient binding region:22-950("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O16658 uniprotkb:Q18025 intact:EBI-2002051|ensemblmetazoa:C03H5.2.1 intact:EBI-313175|ensemblmetazoa:C15H9.4.1 psi-mi:o16658_caeel(display_long)|uniprotkb:C03H5.2(orf name)|uniprotkb:nstp-4(gene name)|psi-mi:nstp-4(display_short)|uniprotkb:CELE_C03H5.2(orf name) psi-mi:q18025_caeel(display_long)|uniprotkb:C15H9.4(orf name)|uniprotkb:CELE_C15H9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460331|imex:IM-11985-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493723.3|wormbase:C03H5.2|interpro:IPR007271(Nucleotide-sugar transporter)|reactome:R-CEL-727802|ensemblmetazoa:C03H5.2.1(transcript)|ensemblmetazoa:WBGene00015404(gene)|go:"GO:0005459"(UDP-galactose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0030173"(integral component of Golgi membrane) refseq:NP_509021.2|wormbase:C15H9.4|ensemblmetazoa:C15H9.4.1(transcript)|ensemblmetazoa:WBGene00015800(gene)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019394|dip:DIP-26183N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Wvd85LmGaCHUGMUa+I1e01qJtpE6239 rogid:xUPBOO1Pp2+5lJVaw5LK3jJ0xng6239 intact-crc:C8BE1E7C5162CAE7|rigid:nfCDZLiqXtVYz/74XhPfKI4BUms false - sufficient binding region:228-467("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45895-1 uniprotkb:Q18025 intact:EBI-6460344|ensemblmetazoa:PAR2.4a.1|ensemblmetazoa:PAR2.4a.2|ensemblmetazoa:PAR2.4a.3 intact:EBI-313175|ensemblmetazoa:C15H9.4.1 psi-mi:p45895-1(display_long)|uniprotkb:Abnormal cell migration(gene name synonym)|uniprotkb:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1(gene name synonym)|uniprotkb:pfc-1(gene name synonym)|uniprotkb:PAR2.4(orf name)|uniprotkb:Chondroitin-polymerizing factor(gene name synonym)|uniprotkb:mig-22(gene name)|psi-mi:mig-22(display_short) psi-mi:q18025_caeel(display_long)|uniprotkb:C15H9.4(orf name)|uniprotkb:CELE_C15H9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460341|imex:IM-11985-464 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:PAR2.4a.1(transcript)|ensemblmetazoa:PAR2.4a.2(transcript)|ensemblmetazoa:PAR2.4a.3(transcript)|ensemblmetazoa:WBGene00003253(gene)|intact:EBI-6500022(isoform-parent) refseq:NP_509021.2|wormbase:C15H9.4|ensemblmetazoa:C15H9.4.1(transcript)|ensemblmetazoa:WBGene00015800(gene)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019394|dip:DIP-26183N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5wIZhWG1W9NjGNUtgDNGipaaRtw6239 rogid:xUPBOO1Pp2+5lJVaw5LK3jJ0xng6239 intact-crc:DE9987FE9F4FFAE1|rigid:npva0XTjxEPHSgMYVFPdqrjLSAU false - sufficient binding region:228-467("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:Q18025 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-313175|ensemblmetazoa:C15H9.4.1 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:q18025_caeel(display_long)|uniprotkb:C15H9.4(orf name)|uniprotkb:CELE_C15H9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460356|imex:IM-11985-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) refseq:NP_509021.2|wormbase:C15H9.4|ensemblmetazoa:C15H9.4.1(transcript)|ensemblmetazoa:WBGene00015800(gene)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019394|dip:DIP-26183N psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:xUPBOO1Pp2+5lJVaw5LK3jJ0xng6239 intact-crc:7752C5C1085899A8|rigid:3KjLJlm0GywtEltrFMv7jOPeXDA false - sufficient binding region:228-467("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19749 uniprotkb:Q19749 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460366|imex:IM-11985-466 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 intact-crc:8AF0F2B7957E5F0F|rigid:DpoHG+kKHuGwTSl0JI0jXoLzoEs false sufficient binding region:222-507("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL3 uniprotkb:Q19335 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 intact:EBI-329629|ensemblmetazoa:F11A10.2.1 psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:q19335_caeel(display_long)|uniprotkb:F11A10.2(orf name)|uniprotkb:repo-1(gene name)|psi-mi:repo-1(display_short)|uniprotkb:CELE_F11A10.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460376|imex:IM-11985-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 refseq:NP_502290.1|wormbase:F11A10.2|reactome:R-CEL-72163|dip:DIP-26535N|ensemblmetazoa:F11A10.2.1(transcript)|ensemblmetazoa:WBGene00008683(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008270"(zinc ion binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR031781|interpro:IPR036236 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 rogid:yL27iBYsk9+fnmokFlhCtfMsQDA6239 intact-crc:3D05245951F82D0B|rigid:xZozEesGuE+42QGXDTdlQJZAKKo false sufficient binding region:220-301("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O77469-3 uniprotkb:P34647-1 intact:EBI-321076|ensemblmetazoa:F56H11.1b.1 intact:EBI-6455889|ensemblmetazoa:ZK632.1a.1 psi-mi:o77469-3(display_long)|uniprotkb:D(isoform synonym)|uniprotkb:fbl-1(gene name)|psi-mi:fbl-1(display_short)|uniprotkb:fbln1(gene name synonym)|uniprotkb:F56H11.1(orf name) psi-mi:p34647-1(display_long)|uniprotkb:ZK632.1(orf name)|uniprotkb:mcm-6(gene name)|psi-mi:mcm-6(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460386|imex:IM-11985-468 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-321052(fbln1_caeel)|ensemblmetazoa:F56H11.1b.1(transcript)|ensemblmetazoa:WBGene00001403(gene) intact:EBI-2006759(isoform-parent)|ensemblmetazoa:WBGene00003158(gene)|ensemblmetazoa:ZK632.1a.1(transcript) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:4T991i3RHYRN1sN45kn841sdAAA6239 rogid:Bv0Zazm8QYFQ5nW05WKMSnLzHVs6239 intact-crc:892D0B5B743BD635|rigid:m8ZzL0qCmjyRdXe1zVnxF1DuwdQ false sufficient binding region:21-689("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17915 uniprotkb:Q65ZJ1 intact:EBI-324099|ensemblmetazoa:K01G5.4.1 intact:EBI-6460396|ensemblmetazoa:C56E6.3b.1 psi-mi:ran_caeel(display_long)|uniprotkb:ran-1(gene name)|psi-mi:ran-1(display_short)|uniprotkb:K01G5.4(orf name)|uniprotkb:Ras-related nuclear protein 1(gene name synonym) psi-mi:q65zj1_caeel(display_long)|uniprotkb:C56E6.3(orf name)|uniprotkb:toe-2(gene name)|psi-mi:toe-2(display_short)|uniprotkb:CELE_C56E6.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460401|imex:IM-11985-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499369.1|wormbase:K01G5.4|ensemblmetazoa:K01G5.4.1(transcript)|ensemblmetazoa:WBGene00004302(gene)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0051301"(cell division)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-CEL-1655829|dip:DIP-25217N|reactome:R-CEL-9615933 ensemblmetazoa:C56E6.3b.1(transcript)|ensemblmetazoa:WBGene00016971(gene)|go:"GO:0016301"(kinase activity)|refseq:NP_001022043.1|wormbase:C56E6.3b|interpro:IPR036388 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:yo75CoWqaTF5xYXAujyoTXXvRw86239 rogid:Bd6MaTCPnGoHXzu2IqsJGGRca7w6239 intact-crc:468B59A4FE4694C0|rigid:CMWgH+klN0VTeH9ygwog8qQO1o8 false - sufficient binding region:216-607("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWR1 uniprotkb:P39745-1 intact:EBI-2002612|intact:EBI-6534487|uniprotkb:A7DTF1|uniprotkb:D3NQA3|ensemblmetazoa:Y11D7A.12a.1 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 psi-mi:flh1_caeel(display_long)|uniprotkb:flh-1(gene name)|psi-mi:flh-1(display_short)|uniprotkb:Y11D7A.12(orf name) psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460421|imex:IM-11985-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501618.2|wormbase:Y11D7A.12a|wormbase:Y11D7A.12b|wormbase:Y11D7A.12c|dip:DIP-24849N|ensemblmetazoa:WBGene00012435(gene)|ensemblmetazoa:Y11D7A.12a.1(transcript)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR007588(Zinc finger, FLYWCH-type) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BUwEONwxmU5dE1HyJh2inla8obA6239 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 intact-crc:D79AF2B810FF0A3D|rigid:1J+0tTPgQEzIIsqP+crQNxsel6I false sufficient binding region:210-507("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61955-1 uniprotkb:Q20898 intact:EBI-6456691|ensemblmetazoa:B0348.6b.1|ensemblmetazoa:B0348.6b.2 intact:EBI-2001916|ensemblmetazoa:F56F3.1.1 psi-mi:o61955-1(display_long)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:B0348.6(orf name)|uniprotkb:ife-3(gene name)|psi-mi:ife-3(display_short) psi-mi:ifet1_caeel(display_long)|uniprotkb:ifet-1(gene name)|psi-mi:ifet-1(display_short)|uniprotkb:Spindle orientation defective protein 2(gene name synonym)|uniprotkb:spn-2(gene name synonym)|uniprotkb:F56F3.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460411|imex:IM-11985-470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-330119(isoform-parent)|ensemblmetazoa:B0348.6b.1(transcript)|ensemblmetazoa:B0348.6b.2(transcript)|ensemblmetazoa:WBGene00002061(gene) refseq:NP_497909.1|wormbase:F56F3.1|interpro:IPR018862|ensemblmetazoa:F56F3.1.1(transcript)|ensemblmetazoa:WBGene00004132(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0043186"(P granule)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:444BHWm5Eiqg+MUqKRgLhbVaxUo6239 rogid:LHR/HcnPNsdVL/6P7RFFLKszhqw6239 intact-crc:259E115FFAD0636E|rigid:zb1CoDXtYY+pK3AdCq72oeXKV2c false - sufficient binding region:21-63("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:O16366 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-316309|ensemblmetazoa:R02F11.4.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:o16366_caeel(display_long)|uniprotkb:R02F11.4(orf name)|uniprotkb:CELE_R02F11.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460431|imex:IM-11985-472 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) refseq:NP_504289.1|wormbase:R02F11.4|reactome:R-CEL-6798695|ensemblmetazoa:R02F11.4.1(transcript)|ensemblmetazoa:WBGene00019842(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045504"(dynein heavy chain binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR025875|interpro:IPR032675|dip:DIP-24518N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:61pQSecbncYjuWhK2dk1vubjKEU6239 intact-crc:E9D0A52D47E4AE18|rigid:yOrGqcNldWDCLQn6vCPPtzU2EmU false - sufficient binding region:209-630("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54811 uniprotkb:P54811 intact:EBI-320245|ensemblmetazoa:C06A1.1.1 intact:EBI-320245|ensemblmetazoa:C06A1.1.1 psi-mi:tera1_caeel(display_long)|uniprotkb:C06A1.1(orf name)|uniprotkb:Cell division cycle-related protein 48.1(gene name synonym)|uniprotkb:p97/CDC48 homolog 1(gene name synonym)|uniprotkb:cdc-48.1(gene name)|psi-mi:cdc-48.1(display_short) psi-mi:tera1_caeel(display_long)|uniprotkb:C06A1.1(orf name)|uniprotkb:Cell division cycle-related protein 48.1(gene name synonym)|uniprotkb:p97/CDC48 homolog 1(gene name synonym)|uniprotkb:cdc-48.1(gene name)|psi-mi:cdc-48.1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460441|imex:IM-11985-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496273.1|wormbase:C06A1.1|ensemblmetazoa:C06A1.1.1(transcript)|ensemblmetazoa:WBGene00007352(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|dip:DIP-26650N refseq:NP_496273.1|wormbase:C06A1.1|ensemblmetazoa:C06A1.1.1(transcript)|ensemblmetazoa:WBGene00007352(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|dip:DIP-26650N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:VgGB6CuL6hJaCop1MLkdaQAjhCE6239 rogid:VgGB6CuL6hJaCop1MLkdaQAjhCE6239 intact-crc:954DD369FE62C969|rigid:PrqOOiPbi4m01IBwkvdiBzAfJ5o false - sufficient binding region:208-470("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34339 uniprotkb:O02328 intact:EBI-2002447|ensemblmetazoa:C27D11.1.1 intact:EBI-2005515|ensemblmetazoa:T23D8.4.1|ensemblmetazoa:T23D8.4.2|ensemblmetazoa:T23D8.4.3 psi-mi:eif3a_caeel(display_long)|uniprotkb:egl-45(gene name)|psi-mi:egl-45(display_short)|uniprotkb:eif-3.A(gene name synonym)|uniprotkb:Egg-laying defective protein 45(gene name synonym)|uniprotkb:C27D11.1(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym) psi-mi:eif3c_caeel(display_long)|uniprotkb:eif-3.C(gene name)|psi-mi:eif-3.C(display_short)|uniprotkb:T23D8.4(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460461|imex:IM-11985-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498698.1|wormbase:C27D11.1|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-72649|interpro:IPR027512|ensemblmetazoa:C27D11.1.1(transcript)|ensemblmetazoa:WBGene00001209(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0018991"(oviposition)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0045182"(translation regulator activity)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m) refseq:NP_492638.1|wormbase:T23D8.4|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-72649|interpro:IPR027516|interpro:IPR036390|ensemblmetazoa:T23D8.4.1(transcript)|ensemblmetazoa:T23D8.4.2(transcript)|ensemblmetazoa:T23D8.4.3(transcript)|ensemblmetazoa:WBGene00001226(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ikwUVKZiw9OM16kt8JEfFxV6xW86239 rogid:h5aGjud8PINPLUJ+H68/LPEhtQA6239 intact-crc:63A8027EEBAF60EE|rigid:2wJsysEEimIrTs7tNQQcmK/5Gi8 false - sufficient binding region:205-898("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:P34331-2 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460451|imex:IM-11985-474 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:u830S0jdkV753ilx7DbxmhPocv86239 intact-crc:70731A83298AD0DD|rigid:tU/yBTMVy3asej4vXKCeiNGk5gc false sufficient binding region:207-403("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q967F1 uniprotkb:O02328 intact:EBI-6460481|ensemblmetazoa:T27F7.3.1 intact:EBI-2005515|ensemblmetazoa:T23D8.4.1|ensemblmetazoa:T23D8.4.2|ensemblmetazoa:T23D8.4.3 psi-mi:q967f1_caeel(display_long)|uniprotkb:T27F7.3(orf name)|uniprotkb:eif-1(gene name)|psi-mi:eif-1(display_short)|uniprotkb:CELE_T27F7.3(orf name) psi-mi:eif3c_caeel(display_long)|uniprotkb:eif-3.C(gene name)|psi-mi:eif-3.C(display_short)|uniprotkb:T23D8.4(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460486|imex:IM-11985-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T27F7.3.1(transcript)|ensemblmetazoa:WBGene00020868(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR001950(Translation initiation factor SUI1)|interpro:IPR005874(Eukaryotic translation initiation factor SUI1)|refseq:NP_001254096.1|wormbase:T27F7.3|interpro:IPR036877 refseq:NP_492638.1|wormbase:T23D8.4|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-72649|interpro:IPR027516|interpro:IPR036390|ensemblmetazoa:T23D8.4.1(transcript)|ensemblmetazoa:T23D8.4.2(transcript)|ensemblmetazoa:T23D8.4.3(transcript)|ensemblmetazoa:WBGene00001226(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b5Xtl9vT72+ECPjEAEKbFNcBDAY6239 rogid:h5aGjud8PINPLUJ+H68/LPEhtQA6239 intact-crc:0C4C119AF6C4689C|rigid:kgRFOPpf6Ft61G+CzXU0+om957Q false - sufficient binding region:205-269("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02482 uniprotkb:O02328 intact:EBI-314716|uniprotkb:P91912|ensemblmetazoa:W02D3.9.1|ensemblmetazoa:W02D3.9.2 intact:EBI-2005515|ensemblmetazoa:T23D8.4.1|ensemblmetazoa:T23D8.4.2|ensemblmetazoa:T23D8.4.3 psi-mi:unc37_caeel(display_long)|uniprotkb:unc-37(gene name)|psi-mi:unc-37(display_short)|uniprotkb:esg(gene name synonym)|uniprotkb:W02D3.9(orf name)|uniprotkb:Uncoordinated protein 37(gene name synonym) psi-mi:eif3c_caeel(display_long)|uniprotkb:eif-3.C(gene name)|psi-mi:eif-3.C(display_short)|uniprotkb:T23D8.4(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460471|imex:IM-11985-476 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-4641265|refseq:NP_491932.1|wormbase:W02D3.9|reactome:R-CEL-3769402|ensemblmetazoa:W02D3.9.1(transcript)|ensemblmetazoa:W02D3.9.2(transcript)|ensemblmetazoa:WBGene00006773(gene)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008134"(transcription factor binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|dip:DIP-27333N|reactome:R-CEL-201722 refseq:NP_492638.1|wormbase:T23D8.4|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-72649|interpro:IPR027516|interpro:IPR036390|ensemblmetazoa:T23D8.4.1(transcript)|ensemblmetazoa:T23D8.4.2(transcript)|ensemblmetazoa:T23D8.4.3(transcript)|ensemblmetazoa:WBGene00001226(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+e4X3QH+GChhuO2oAhaNGVwnO/o6239 rogid:h5aGjud8PINPLUJ+H68/LPEhtQA6239 intact-crc:DB6848568513B9DC|rigid:J0fT6EGmAWiZb0GltL8nM1AVzFY false - sufficient binding region:205-898("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19713 uniprotkb:Q9GYS8 intact:EBI-6458795|ensemblmetazoa:F22B5.9.1 intact:EBI-2006979|ensemblmetazoa:T08B2.9a.1|ensemblmetazoa:T08B2.9a.2 psi-mi:syfb_caeel(display_long)|uniprotkb:fars-3(gene name)|psi-mi:fars-3(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:frs-2(gene name synonym)|uniprotkb:F22B5.9(orf name) psi-mi:q9gys8_caeel(display_long)|uniprotkb:fars-1(gene name)|psi-mi:fars-1(display_short)|uniprotkb:CELE_T08B2.9(orf name)|uniprotkb:T08B2.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460506|imex:IM-11985-479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F22B5.9.1(transcript)|ensemblmetazoa:WBGene00001498(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR040659|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|refseq:NP_495785.1|wormbase:F22B5.9|interpro:IPR041616 interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|refseq:NP_491792.1|wormbase:T08B2.9a|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR036282|ensemblmetazoa:T08B2.9a.1(transcript)|ensemblmetazoa:T08B2.9a.2(transcript)|ensemblmetazoa:WBGene00001497(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vnO3fcS4LkBf8htippBIQGUn4M06239 rogid:EEUpEXyKvX9M3qQ6g+BZ8L3hHAQ6239 intact-crc:387BE1703F5DB400|rigid:WpHoxNDgINluh2MHzcUt3LqxSzE false - sufficient binding region:203-552("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21740 uniprotkb:Q95YF3 intact:EBI-314602|ensemblmetazoa:R05D11.8.1 intact:EBI-314525|ensemblmetazoa:C07H6.5.1 psi-mi:q21740_caeel(display_long)|uniprotkb:edc-3(gene name)|psi-mi:edc-3(display_short)|uniprotkb:CELE_R05D11.8(orf name)|uniprotkb:R05D11.8(orf name) psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460496|imex:IM-11985-478 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492328.1|wormbase:R05D11.8|ensemblmetazoa:R05D11.8.1(transcript)|ensemblmetazoa:WBGene00011036(gene)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|interpro:IPR025609|interpro:IPR025762|dip:DIP-27240N|reactome:R-CEL-430039 refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:4aBKhfeToK+re+wdTq9qCFDdfx46239 rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239 intact-crc:8D5C305E47255803|rigid:3U9PYWEctAd3l5b8sTC9pXCdM7w false sufficient binding region:203-566("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P45970 uniprotkb:P45970 intact:EBI-320134|ensemblmetazoa:T09A5.10.1|ensemblmetazoa:T09A5.10.2 intact:EBI-320134|ensemblmetazoa:T09A5.10.1|ensemblmetazoa:T09A5.10.2 psi-mi:lin5_caeel(display_long)|uniprotkb:lin-5(gene name)|psi-mi:lin-5(display_short)|uniprotkb:T09A5.10(orf name)|uniprotkb:Abnormal cell lineage protein 5(gene name synonym) psi-mi:lin5_caeel(display_long)|uniprotkb:lin-5(gene name)|psi-mi:lin-5(display_short)|uniprotkb:T09A5.10(orf name)|uniprotkb:Abnormal cell lineage protein 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460516|imex:IM-11985-480 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495654.1|wormbase:T09A5.10|ensemblmetazoa:T09A5.10.1(transcript)|ensemblmetazoa:T09A5.10.2(transcript)|ensemblmetazoa:WBGene00002994(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0008406"(gonad development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0040011"(locomotion)|go:"GO:0051233"(spindle midzone)|go:"GO:0051296"(establishment of meiotic spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|dip:DIP-24397N refseq:NP_495654.1|wormbase:T09A5.10|ensemblmetazoa:T09A5.10.1(transcript)|ensemblmetazoa:T09A5.10.2(transcript)|ensemblmetazoa:WBGene00002994(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007399"(nervous system development)|go:"GO:0008406"(gonad development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0040011"(locomotion)|go:"GO:0051233"(spindle midzone)|go:"GO:0051296"(establishment of meiotic spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|dip:DIP-24397N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:P55+FcFiYu1Or6aQZkef89JaIE86239 rogid:P55+FcFiYu1Or6aQZkef89JaIE86239 intact-crc:D9803CF74B101E04|rigid:PnZWHASiWD67gd1mDrmKIucPiPQ false - sufficient binding region:202-604("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:Q95XR4 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-322782|ensemblmetazoa:Y39G10AR.10.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:epg2_caeel(display_long)|uniprotkb:Y39G10AR.10(orf name)|uniprotkb:epg-2(gene name)|psi-mi:epg-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460526|imex:IM-11985-481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) refseq:NP_490955.1|wormbase:Y39G10AR.10|ensemblmetazoa:WBGene00021468(gene)|ensemblmetazoa:Y39G10AR.10.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016236"(macroautophagy)|go:"GO:1902902"(negative regulation of autophagosome assembly)|dip:DIP-27321N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:0Q+7Kzsl+oA/J2g1igYZC/y11kI6239 intact-crc:458A81C76E00CA66|rigid:Iu7rUqpWMosj8uFj5Ar1eoeCE0I false - sufficient binding region:202-470("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01902 uniprotkb:Q95XR4 intact:EBI-317316|ensemblmetazoa:F59E12.11.1 intact:EBI-322782|ensemblmetazoa:Y39G10AR.10.1 psi-mi:o01902_caeel(display_long)|uniprotkb:sam-4(gene name)|psi-mi:sam-4(display_short)|uniprotkb:CELE_F59E12.11(orf name)|uniprotkb:F59E12.11(orf name) psi-mi:epg2_caeel(display_long)|uniprotkb:Y39G10AR.10(orf name)|uniprotkb:epg-2(gene name)|psi-mi:epg-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460536|imex:IM-11985-482 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495102.1|ensemblmetazoa:F59E12.11.1(transcript)|ensemblmetazoa:WBGene00019126(gene)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0040011"(locomotion)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903746"(positive regulation of pharyngeal pumping)|interpro:IPR018780|go:"GO:0099078"(BORC complex)|wormbase:F59E12.11|dip:DIP-26735N refseq:NP_490955.1|wormbase:Y39G10AR.10|ensemblmetazoa:WBGene00021468(gene)|ensemblmetazoa:Y39G10AR.10.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016236"(macroautophagy)|go:"GO:1902902"(negative regulation of autophagosome assembly)|dip:DIP-27321N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CYh19fO/xuev1wnk3G7FjIjp+Dg6239 rogid:0Q+7Kzsl+oA/J2g1igYZC/y11kI6239 intact-crc:F8A697ACAFA7FBAD|rigid:RNX3b/Y4NqsLXKVs1yTmGfYOqaY false - sufficient binding region:202-336("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12114 uniprotkb:Q21443 intact:EBI-2001946|uniprotkb:Q17509|ensemblmetazoa:B0491.2.1|ensemblmetazoa:B0491.2.2|ensemblmetazoa:B0491.2.3 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:sqt1_caeel(display_long)|uniprotkb:sqt-1(gene name)|psi-mi:sqt-1(display_short)|uniprotkb:rol-5(gene name synonym)|uniprotkb:Protein squat-1(gene name synonym)|uniprotkb:Protein roller-5(gene name synonym)|uniprotkb:B0491.2(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460546|imex:IM-11985-483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496421.1|wormbase:B0491.2|interpro:IPR002486(Nematode cuticle collagen, N-terminal)|interpro:IPR008160(Collagen triple helix repeat)|ensemblmetazoa:B0491.2.1(transcript)|ensemblmetazoa:B0491.2.2(transcript)|ensemblmetazoa:B0491.2.3(transcript)|ensemblmetazoa:WBGene00005016(gene)|go:"GO:0005581"(collagen trimer)|go:"GO:0040002"(collagen and cuticulin-based cuticle development)|go:"GO:0042329"(structural constituent of collagen and cuticulin-based cuticle)|go:"GO:0042338"(cuticle development involved in collagen and cuticulin-based cuticle molting cycle) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WMpqKz4i0X/wUmyEftH/bk8FopU6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:92A1F0FB6CD2B3DF|rigid:nKFzV/6dh6V9IUx9rEs0jpF5NiU false - sufficient binding region:201-566("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:Q8MPS6 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-6457529|ensemblmetazoa:ZK742.1b.1|ensemblmetazoa:ZK742.1b.2|ensemblmetazoa:ZK742.1b.3 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:q8mps6_caeel(display_long)|uniprotkb:ZK742.1(orf name)|uniprotkb:xpo-1(gene name)|psi-mi:xpo-1(display_short)|uniprotkb:CELE_ZK742.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460556|imex:IM-11985-484 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N ensemblmetazoa:WBGene00002078(gene)|ensemblmetazoa:ZK742.1b.1(transcript)|ensemblmetazoa:ZK742.1b.2(transcript)|ensemblmetazoa:ZK742.1b.3(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_741568.1|wormbase:ZK742.1b psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:RNDp87iDe63C67Ef2THc2ppRDDY6239 intact-crc:01B16C21A538E3F2|rigid:0HOUaTYx5K9geRTrcanfxiVTCTo false sufficient binding region:201-566("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23593 uniprotkb:Q21443 intact:EBI-6460566|ensemblmetazoa:ZK792.2.1|ensemblmetazoa:ZK792.2.2|ensemblmetazoa:ZK792.2.3 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:inx8_caeel(display_long)|uniprotkb:Protein opu-8(gene name synonym)|uniprotkb:opu-8(gene name synonym)|uniprotkb:ZK792.2(orf name)|uniprotkb:inx-8(gene name)|psi-mi:inx-8(display_short) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460571|imex:IM-11985-485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00002130(gene)|ensemblmetazoa:ZK792.2.1(transcript)|ensemblmetazoa:ZK792.2.2(transcript)|ensemblmetazoa:ZK792.2.3(transcript)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0055077"(gap junction hemi-channel activity)|interpro:IPR000990(Innexin)|refseq:NP_502209.1|wormbase:ZK792.2 reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5X1kqdk1VN+p4aaWMmR0YoK5KTs6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:B835263685337833|rigid:L6cO3GfJycAHN0gqj7aNRB5zbBU false - sufficient binding region:201-566("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95YF3 uniprotkb:Q9XUS3 intact:EBI-314525|ensemblmetazoa:C07H6.5.1 intact:EBI-322485|ensemblmetazoa:K08E3.7a.1|ensemblmetazoa:K08E3.7a.2 psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short) psi-mi:q9xus3_caeel(display_long)|uniprotkb:pdr-1(gene name)|psi-mi:pdr-1(display_short)|uniprotkb:CELE_K08E3.7(orf name)|uniprotkb:K08E3.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460591|imex:IM-11985-487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N refseq:NP_499846.2|wormbase:K08E3.7a|ensemblmetazoa:K08E3.7a.1(transcript)|ensemblmetazoa:K08E3.7a.2(transcript)|ensemblmetazoa:WBGene00003967(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR031127|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|dip:DIP-27410N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239 rogid:QjMGF5rOOY7sjRKY+t/HefjZZeE6239 intact-crc:6DE8538ED7564E0B|rigid:x6SaIzMMTtvwK8plDeSdZ0niuGo false - sufficient binding region:201-386("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:Q09583 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-315406|ensemblmetazoa:ZK945.2.1|ensemblmetazoa:ZK945.2.2 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:psa3_caeel(display_long)|uniprotkb:pas-7(gene name)|psi-mi:pas-7(display_short)|uniprotkb:ZK945.2(orf name)|uniprotkb:Proteasome subunit alpha 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460581|imex:IM-11985-486 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N refseq:NP_496177.2|wormbase:ZK945.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:WBGene00003928(gene)|ensemblmetazoa:ZK945.2.1(transcript)|ensemblmetazoa:ZK945.2.2(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|interpro:IPR037555|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:OOdurA40PpJd/0X3BA8Z5ZWqCuM6239 intact-crc:D7076F9DFE44FA4B|rigid:wZ+E/u+f1GLENDDN7g3JdGukzL0 false sufficient binding region:201-566("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XUS3 uniprotkb:P90868 intact:EBI-322485|ensemblmetazoa:K08E3.7a.1|ensemblmetazoa:K08E3.7a.2 intact:EBI-317074|ensemblmetazoa:F39H11.5.1 psi-mi:q9xus3_caeel(display_long)|uniprotkb:pdr-1(gene name)|psi-mi:pdr-1(display_short)|uniprotkb:CELE_K08E3.7(orf name)|uniprotkb:K08E3.7(orf name) psi-mi:p90868_caeel(display_long)|uniprotkb:pbs-7(gene name)|psi-mi:pbs-7(display_short)|uniprotkb:F39H11.5(orf name)|uniprotkb:CELE_F39H11.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460601|imex:IM-11985-488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499846.2|wormbase:K08E3.7a|ensemblmetazoa:K08E3.7a.1(transcript)|ensemblmetazoa:K08E3.7a.2(transcript)|ensemblmetazoa:WBGene00003967(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR031127|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|dip:DIP-27410N reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_492354.1|wormbase:F39H11.5|ensemblmetazoa:F39H11.5.1(transcript)|ensemblmetazoa:WBGene00003953(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR029055|reactome:R-CEL-5632684|reactome:R-CEL-8932339|dip:DIP-26967N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:QjMGF5rOOY7sjRKY+t/HefjZZeE6239 rogid:b0ur9kPZL37Eqp8qt6e41061Zc06239 intact-crc:E989B49BED15776D|rigid:zaLK0J0pVb4BGGeRz5qedAgmrxA false sufficient binding region:201-386("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QC4 uniprotkb:Q9XUS3 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 intact:EBI-322485|ensemblmetazoa:K08E3.7a.1|ensemblmetazoa:K08E3.7a.2 psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:q9xus3_caeel(display_long)|uniprotkb:pdr-1(gene name)|psi-mi:pdr-1(display_short)|uniprotkb:CELE_K08E3.7(orf name)|uniprotkb:K08E3.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460611|imex:IM-11985-489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 refseq:NP_499846.2|wormbase:K08E3.7a|ensemblmetazoa:K08E3.7a.1(transcript)|ensemblmetazoa:K08E3.7a.2(transcript)|ensemblmetazoa:WBGene00003967(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1900407"(regulation of cellular response to oxidative stress)|go:"GO:1901075"(negative regulation of engulfment of apoptotic cell)|interpro:IPR000626(Ubiquitin)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR003977(Parkin)|interpro:IPR029071|interpro:IPR031127|interpro:IPR041170|interpro:IPR041565|interpro:IPR044066|dip:DIP-27410N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 rogid:QjMGF5rOOY7sjRKY+t/HefjZZeE6239 intact-crc:C2AC490E0DC695A1|rigid:tFZ7vnPR+RB1kDC/tWjtLzOTTDc false - sufficient binding region:201-386("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01422 uniprotkb:Q9XVU8 intact:EBI-331413|ensemblmetazoa:B0025.2.1|ensemblmetazoa:B0025.2.2 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:csn2_caeel(display_long)|uniprotkb:B0025.2(orf name)|uniprotkb:csn-2(gene name)|psi-mi:csn-2(display_short) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460631|imex:IM-11985-491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491740.1|wormbase:B0025.2|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-24665N|ensemblmetazoa:B0025.2.1(transcript)|ensemblmetazoa:B0025.2.2(transcript)|ensemblmetazoa:WBGene00000814(gene)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|reactome:R-CEL-5696394 ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:qwX/mKYLxZitZLkfNa3RPYDLYyo6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:BB67F084905EE1F6|rigid:Qh9K6VIuwpo4R5EHQTUHYsRiO+M false - sufficient binding region:200-706("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22752 uniprotkb:O45087 intact:EBI-328280|ensemblmetazoa:T24H10.6.1 intact:EBI-313406|ensemblmetazoa:C17H12.1.1 psi-mi:q22752_caeel(display_long)|uniprotkb:dyrb-1(gene name)|psi-mi:dyrb-1(display_short)|uniprotkb:T24H10.6(orf name)|uniprotkb:CELE_T24H10.6(orf name) psi-mi:o45087_caeel(display_long)|uniprotkb:dyci-1(gene name)|psi-mi:dyci-1(display_short)|uniprotkb:C17H12.1(orf name)|uniprotkb:CELE_C17H12.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460621|imex:IM-11985-490 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495943.1|wormbase:T24H10.6|reactome:R-CEL-5620924|dip:DIP-24279N|ensemblmetazoa:T24H10.6.1(transcript)|ensemblmetazoa:WBGene00012004(gene)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR004942(Dynein light chain-related)|interpro:IPR016561(Dynein light chain, roadblock-type)|go:"GO:0005813"(centrosome) refseq:NP_501038.1|ensemblmetazoa:C17H12.1.1(transcript)|ensemblmetazoa:WBGene00015927(gene)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0010970"(transport along microtubule)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-CEL-6811436|wormbase:C17H12.1a|reactome:R-CEL-9646399|dip:DIP-25870N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hSEbK1Z9HGIG7/GWt6ajVc4zadI6239 rogid:CpgxxRfSkDSDUCfcxsooWU8jsv06239 intact-crc:46051B550FD2AFE4|rigid:OTv/p0CbQ3jjVY/e4p0cWErIMpQ false - sufficient binding region:201-246("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q95Y13 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460651|imex:IM-11985-493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 intact-crc:7945CF1D8F1F37D5|rigid:YjElZu87Elc5J8cp2GzjbArdxOs false sufficient binding region:200-706("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:G5ECR7 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-330567|ensemblmetazoa:Y41C4A.10.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:g5ecr7_caeel(display_long)|uniprotkb:3L686(gene name synonym)|uniprotkb:elb-1(gene name)|psi-mi:elb-1(display_short)|uniprotkb:Y41C4A.10(orf name)|uniprotkb:CELE_Y41C4A.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460641|imex:IM-11985-492 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 uniprotkb:Q9XWU4(uniprot-removed-ac)|refseq:NP_499517.1|reactome:R-CEL-674695|reactome:R-CEL-6796648|wormbase:Y41C4A.10|interpro:IPR039049|interpro:IPR029071|reactome:R-CEL-1234176|reactome:R-CEL-983168|reactome:R-CEL-8951664|ensemblmetazoa:WBGene00001235(gene)|ensemblmetazoa:Y41C4A.10.1(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|reactome:R-CEL-75955|reactome:R-CEL-112382 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:nd6q1xH1t5OIdfLT3hHtTS3gTqU6239 intact-crc:C72251AD05316409|rigid:XlKLW7iBhKQ6hB5BuJJOEr6PZUE false sufficient binding region:200-706("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09278 uniprotkb:Q19626 intact:EBI-317279|ensemblmetazoa:C45G9.5.1 intact:EBI-2002814|ensemblmetazoa:F20B6.2.1 psi-mi:yqi5_caeel(display_long)|uniprotkb:C45G9.5(orf name) psi-mi:vatb_caeel(display_long)|uniprotkb:vha-12(gene name)|psi-mi:vha-12(display_short)|uniprotkb:Vacuolar proton pump subunit B(gene name synonym)|uniprotkb:F20B6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460661|imex:IM-11985-494 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498072.1|wormbase:C45G9.5|ensemblmetazoa:C45G9.5.1(transcript)|ensemblmetazoa:WBGene00016676(gene)|dip:DIP-27061N refseq:NP_508711.1|wormbase:F20B6.2|interpro:IPR020003|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR022879|reactome:R-CEL-77387|reactome:R-CEL-1222556|reactome:R-CEL-9639288|interpro:IPR027417|reactome:R-CEL-917977|reactome:R-CEL-983712|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060142"(regulation of syncytium formation by plasma membrane fusion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|ensemblmetazoa:F20B6.2.1(transcript)|ensemblmetazoa:WBGene00006921(gene)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0008219"(cell death)|go:"GO:0015988"(energy coupled proton transmembrane transport, against electrochemical gradient)|go:"GO:0016787"(hydrolase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mUD/3V1JUulzNjP4a+xPTmM5W9o6239 rogid:9yAsY1/NwUe59iQnR0M2m1fXeAE6239 intact-crc:06376F35BF0C2D1B|rigid:elkTwky7MB0ap15N/JnR8rFPYVA false - sufficient binding region:200-246("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2D9 uniprotkb:Q18194 intact:EBI-313125|ensemblmetazoa:Y46G5A.31.1 intact:EBI-2002421|ensemblmetazoa:C26B2.1.1 psi-mi:gys_caeel(display_long)|uniprotkb:Y46G5A.31(orf name)|uniprotkb:gsy-1(gene name)|psi-mi:gsy-1(display_short) psi-mi:q18194_caeel(display_long)|uniprotkb:dnc-4(gene name)|psi-mi:dnc-4(display_short)|uniprotkb:CELE_C26B2.1(orf name)|uniprotkb:C26B2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460671|imex:IM-11985-495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496736.1|wormbase:Y46G5A.31|reactome:R-CEL-3322077|ensemblmetazoa:WBGene00001793(gene)|ensemblmetazoa:Y46G5A.31.1(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:4QLB|dip:DIP-26557N refseq:NP_501344.1|wormbase:C26B2.1|interpro:IPR008603(Dynactin p62)|reactome:R-CEL-6811436|reactome:R-CEL-3371497|reactome:R-CEL-6807878|ensemblmetazoa:C26B2.1.1(transcript)|ensemblmetazoa:WBGene00016124(gene)|go:"GO:0005869"(dynactin complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b+SLtpyJP/vLcnk35dGAJgRcz946239 rogid:XgXybdcDeIC6UEGYvvS5eSemoiE6239 intact-crc:697EBF5E8490E677|rigid:02UWo2mEqlcXHMgZOBohHJ1uYQc false - sufficient binding region:198-297("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22253 uniprotkb:O61792 intact:EBI-326317|ensemblmetazoa:T06D8.8.1|ensemblmetazoa:T06D8.8.2 intact:EBI-324407|ensemblmetazoa:R12E2.3.1 psi-mi:q22253_caeel(display_long)|uniprotkb:rpn-9(gene name)|psi-mi:rpn-9(display_short)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:CELE_T06D8.8(orf name)|uniprotkb:T06D8.8(orf name) psi-mi:o61792_caeel(display_long)|uniprotkb:rpn-8(gene name)|psi-mi:rpn-8(display_short)|uniprotkb:R12E2.3(orf name)|uniprotkb:CELE_R12E2.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460681|imex:IM-11985-496 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_496405.1|wormbase:T06D8.8|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-1234176|reactome:R-CEL-1236978|ensemblmetazoa:T06D8.8.1(transcript)|ensemblmetazoa:T06D8.8.2(transcript)|ensemblmetazoa:WBGene00004465(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043248"(proteasome assembly)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR035298|interpro:IPR036390|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-8932339 interpro:IPR024969|refseq:NP_491319.1|wormbase:R12E2.3|interpro:IPR000555(Mov34/MPN/PAD-1)|ensemblmetazoa:R12E2.3.1(transcript)|ensemblmetazoa:WBGene00004464(gene)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR033858|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR037518|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128|reactome:R-CEL-8932339 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:AS9yH/PgziWyyFfsUDf2NE1M4iw6239 rogid:W/94trr894y/hNnW+ibZRLHDRlg6239 intact-crc:C7CD21C29422D300|rigid:x5ETKmPyoBiFh2sAe6SZJaCKjuU false - sufficient binding region:197-362("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N359 uniprotkb:C5VUK2 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 intact:EBI-6458987|ensemblmetazoa:Y67H2A.6b.1 psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:c5vuk2_caeel(display_long)|uniprotkb:Y67H2A.6(orf name)|uniprotkb:csn-6(gene name)|psi-mi:csn-6(display_short)|uniprotkb:CELE_Y67H2A.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460691|imex:IM-11985-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 ensemblmetazoa:WBGene00000818(gene)|ensemblmetazoa:Y67H2A.6b.1(transcript)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|refseq:NP_001255725.1|wormbase:Y67H2A.6b|interpro:IPR037518 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 rogid:Hf0v9RIBG3fVF4QivzWz2C3lwEA6239 intact-crc:81C9895D7D1D5656|rigid:ml3cMHn9awc0KXYgm051mdLgAgI false - sufficient binding region:197-295("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90868 intact:EBI-6458701 intact:EBI-317074|ensemblmetazoa:F39H11.5.1 intact:EBI-6306432 psi-mi:p90868_caeel(display_long)|uniprotkb:pbs-7(gene name)|psi-mi:pbs-7(display_short)|uniprotkb:F39H11.5(orf name)|uniprotkb:CELE_F39H11.5(orf name) psi-mi:ebi6306432(display_short)|psi-mi:EBI-6458701(display_long)|intact:Y57A10A.24x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460701|imex:IM-11985-498 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_492354.1|wormbase:F39H11.5|ensemblmetazoa:F39H11.5.1(transcript)|ensemblmetazoa:WBGene00003953(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR029055|reactome:R-CEL-5632684|reactome:R-CEL-8932339|dip:DIP-26967N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:b0ur9kPZL37Eqp8qt6e41061Zc06239 - intact-crc:5C9E85A52612E2C4 false - sufficient binding region:197-287("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XXI9 uniprotkb:P34647-1 intact:EBI-323002|ensemblmetazoa:Y17G7B.5a.2|ensemblmetazoa:Y17G7B.5a.1 intact:EBI-6455889|ensemblmetazoa:ZK632.1a.1 psi-mi:q9xxi9_caeel(display_long)|uniprotkb:mcm-2(gene name)|psi-mi:mcm-2(display_short)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:CELE_Y17G7B.5(orf name)|uniprotkb:Y17G7B.5(orf name) psi-mi:p34647-1(display_long)|uniprotkb:ZK632.1(orf name)|uniprotkb:mcm-6(gene name)|psi-mi:mcm-6(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460711|imex:IM-11985-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022416.1|wormbase:Y17G7B.5a|ensemblmetazoa:WBGene00003154(gene)|ensemblmetazoa:Y17G7B.5a.1(transcript)|ensemblmetazoa:Y17G7B.5a.2(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0045120"(pronucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|interpro:IPR008045(MCM protein 2)|dip:DIP-26513N|reactome:R-CEL-69052|reactome:R-CEL-68962|reactome:R-CEL-176187|reactome:R-CEL-68949 intact:EBI-2006759(isoform-parent)|ensemblmetazoa:WBGene00003158(gene)|ensemblmetazoa:ZK632.1a.1(transcript) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:kFk0JkaNxVucbluwusDJMPtCOdo6239 rogid:Bv0Zazm8QYFQ5nW05WKMSnLzHVs6239 intact-crc:70EB071DBBA79DEF|rigid:bxQd8bTzcpWJMEfhOlSlqgqlt5s false sufficient binding region:196-881("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL3 uniprotkb:Q23237 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 intact:EBI-314040|ensemblmetazoa:Y38A8.2.1 psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:psb3_caeel(display_long)|uniprotkb:pbs-3(gene name)|psi-mi:pbs-3(display_short)|uniprotkb:Y38A8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460721|imex:IM-11985-500 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 reactome:R-CEL-8932339|refseq:NP_494913.1|wormbase:Y38A8.2|reactome:R-CEL-5632684|ensemblmetazoa:WBGene00003949(gene)|ensemblmetazoa:Y38A8.2.1(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-25063N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 rogid:XDQsAOH8E9LxVDloQ25KGEoFB6c6239 intact-crc:AF98EE152F729CE6|rigid:jHy/IidqJfJkiiWYXEiauSqq1SM false sufficient binding region:196-596("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62479 uniprotkb:Q20010 intact:EBI-327247|ensemblmetazoa:Y45F10D.9.1 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 psi-mi:sas6_caeel(display_long)|uniprotkb:sas-6(gene name)|psi-mi:sas-6(display_short)|uniprotkb:Y45F10D.9(orf name) psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460731|imex:IM-11985-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502660.1|wormbase:Y45F10D.9|ensemblmetazoa:WBGene00012888(gene)|ensemblmetazoa:Y45F10D.9.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR032396|interpro:IPR038558|rcsb pdb:3PYI|rcsb pdb:4G79|rcsb pdb:4GEU|rcsb pdb:4GEX|rcsb pdb:4GFA|rcsb pdb:4GFC|rcsb pdb:4GKW|dip:DIP-24495N refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bjwQTTv7ws6z/T+fM8bNGnEsEXk6239 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 intact-crc:C2D475573969CFA8|rigid:WJD6GBhR2Pm0YPFbrtwwyb0bVfs false - sufficient binding region:196-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QC4 uniprotkb:Q20010 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460741|imex:IM-11985-502 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 intact-crc:9E59F7339902469D|rigid:3q1miM6N15I8t8KC9Kq30b2mA+o false - sufficient binding region:196-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P53016 uniprotkb:Q18547 intact:EBI-318155|ensemblmetazoa:F31E3.3.1 intact:EBI-314981|ensemblmetazoa:C39E9.13.1 psi-mi:rfc4_caeel(display_long)|uniprotkb:F31E3.3(orf name)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:rfc-4(gene name)|psi-mi:rfc-4(display_short) psi-mi:q18547_caeel(display_long)|uniprotkb:rfc-3(gene name)|psi-mi:rfc-3(display_short)|uniprotkb:CELE_C39E9.13(orf name)|uniprotkb:C39E9.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460751|imex:IM-11985-503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498521.1|wormbase:F31E3.3|ensemblmetazoa:F31E3.3.1(transcript)|ensemblmetazoa:WBGene00004340(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|dip:DIP-24293N|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-110320|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-69091 refseq:NP_502517.1|wormbase:C39E9.13|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-110320|reactome:R-CEL-69091|ensemblmetazoa:C39E9.13.1(transcript)|ensemblmetazoa:WBGene00004339(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|go:"GO:0005663"(DNA replication factor C complex)|dip:DIP-27479N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:17GeJI7eKmB2+zqvOLntNT/n4eo6239 rogid:9i4qy+nQFgxA2CsSmCxrFmzOsfM6239 intact-crc:0D88D3AB09419E7C|rigid:YbSPT11jLj2rOo/eocr3k8kMTHk false sufficient binding region:196-334("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:Q09601 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-2004755|uniprotkb:O62340|ensemblmetazoa:R06F6.5b.1 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:nup35_caeel(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460761|imex:IM-11985-504 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) interpro:IPR017389(Nucleoporin, NUP53)|refseq:NP_496324.1|refseq:NP_496325.1|wormbase:R06F6.5a|wormbase:R06F6.5b|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:2D2F1B9D33BD4F4B|rigid:dZCFueXcCHuxuJ0mDGvkK8BXXTU false - sufficient binding region:196-301("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34429 uniprotkb:P53016 intact:EBI-315471|uniprotkb:Q8ST15|ensemblmetazoa:F44B9.8.1 intact:EBI-318155|ensemblmetazoa:F31E3.3.1 psi-mi:rfc5_caeel(display_long)|uniprotkb:F44B9.8(orf name)|uniprotkb:Activator 1 subunit 5(gene name synonym) psi-mi:rfc4_caeel(display_long)|uniprotkb:F31E3.3(orf name)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:rfc-4(gene name)|psi-mi:rfc-4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460771|imex:IM-11985-505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498750.2|wormbase:F44B9.8|reactome:R-CEL-110320|reactome:R-CEL-69091|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|ensemblmetazoa:F44B9.8.1(transcript)|ensemblmetazoa:WBGene00018409(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|dip:DIP-27001N refseq:NP_498521.1|wormbase:F31E3.3|ensemblmetazoa:F31E3.3.1(transcript)|ensemblmetazoa:WBGene00004340(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|dip:DIP-24293N|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-110320|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-69091 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:RbC1EnOYlqMnvDR/47NfuUSHZVA6239 rogid:17GeJI7eKmB2+zqvOLntNT/n4eo6239 intact-crc:6045830AAE71E66F|rigid:14+Um5YhbiFaWin8sepPur9hwn4 false sufficient binding region:19-368("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZH2 uniprotkb:Q95XZ0 intact:EBI-316221|ensemblmetazoa:T22D1.10.1|ensemblmetazoa:T22D1.10.2 intact:EBI-2006014|uniprotkb:Q3V5K1|uniprotkb:Q95XY9|ensemblmetazoa:Y51H7C.6a.1 psi-mi:ruvb2_caeel(display_long)|uniprotkb:ruvb-2(gene name)|psi-mi:ruvb-2(display_short)|uniprotkb:Reptin(gene name synonym)|uniprotkb:T22D1.10(orf name) psi-mi:cog4_caeel(display_long)|uniprotkb:cogc-4(gene name)|psi-mi:cogc-4(display_short)|uniprotkb:Component of oligomeric Golgi complex 4(gene name synonym)|uniprotkb:Y51H7C.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460781|imex:IM-11985-506 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:NP_501067.1|wormbase:T22D1.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR042487|interpro:IPR037942|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027238|ensemblmetazoa:T22D1.10.1(transcript)|ensemblmetazoa:T22D1.10.2(transcript)|ensemblmetazoa:WBGene00020687(gene)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR041048 refseq:NP_001033341.1|refseq:NP_493966.1|refseq:NP_493967.1|wormbase:Y51H7C.6a|wormbase:Y51H7C.6b|wormbase:Y51H7C.6c|interpro:IPR013167(COG4 transport)|reactome:R-CEL-6807878|reactome:R-CEL-6811438|ensemblmetazoa:WBGene00021784(gene)|ensemblmetazoa:Y51H7C.6a.1(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0048213"(Golgi vesicle prefusion complex stabilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:dn+URkAlY1J22vwLn+hGlRujVis6239 rogid:BBSGzEvj00FcUTtxYSfPSg6jNHQ6239 intact-crc:C4D876455409A3E0|rigid:cSOPxTLkpkISOP9cR2I8cHHI7gQ false - sufficient binding region:193-295("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:P10567 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-318168|uniprotkb:Q93214|uniprotkb:Q93439|ensemblmetazoa:F07A5.7a.1|ensemblmetazoa:F07A5.7a.2|ensemblmetazoa:F07A5.7a.3|ensemblmetazoa:F07A5.7a.4|intact:EBI-11465138|intact:EBI-11466975|intact:EBI-6460025|uniprotkb:B3WFV3 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:mysp_caeel(display_long)|uniprotkb:unc-15(gene name)|psi-mi:unc-15(display_short)|uniprotkb:F07A5.7(orf name)|uniprotkb:Uncoordinated protein 15(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460791|imex:IM-11985-507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) refseq:NP_492085.1|wormbase:F07A5.7a|ensemblmetazoa:F07A5.7a.1(transcript)|ensemblmetazoa:F07A5.7a.2(transcript)|ensemblmetazoa:F07A5.7a.3(transcript)|ensemblmetazoa:F07A5.7a.4(transcript)|ensemblmetazoa:WBGene00006754(gene)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016459"(myosin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032982"(myosin filament)|go:"GO:0040011"(locomotion)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060279"(positive regulation of ovulation)|go:"GO:0060298"(positive regulation of sarcomere organization)|interpro:IPR002928(Myosin tail)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:NP_001129763.1|wormbase:F07A5.7b|dip:DIP-24443N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/02/23 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:qDSWRA42Ad8ZvgnKN1TomAfe1f46239 intact-crc:EB1A3860C5DD1800|rigid:jvNiwPNyYRda8dM1vgowBWeAYXk false - sufficient binding region:508-872("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2V0X4 uniprotkb:P10567 intact:EBI-6456854 intact:EBI-318168|uniprotkb:Q93214|uniprotkb:Q93439|ensemblmetazoa:F07A5.7a.1|ensemblmetazoa:F07A5.7a.2|ensemblmetazoa:F07A5.7a.3|ensemblmetazoa:F07A5.7a.4|intact:EBI-11465138|intact:EBI-11466975|intact:EBI-6460025|uniprotkb:B3WFV3 psi-mi:q2v0x4_caeel(display_long)|uniprotkb:cogc-3(gene name)|psi-mi:cogc-3(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 3(gene name synonym) psi-mi:mysp_caeel(display_long)|uniprotkb:unc-15(gene name)|psi-mi:unc-15(display_short)|uniprotkb:F07A5.7(orf name)|uniprotkb:Uncoordinated protein 15(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460801|imex:IM-11985-508 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007265(Sec34-like protein) refseq:NP_492085.1|wormbase:F07A5.7a|ensemblmetazoa:F07A5.7a.1(transcript)|ensemblmetazoa:F07A5.7a.2(transcript)|ensemblmetazoa:F07A5.7a.3(transcript)|ensemblmetazoa:F07A5.7a.4(transcript)|ensemblmetazoa:WBGene00006754(gene)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016459"(myosin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032982"(myosin filament)|go:"GO:0040011"(locomotion)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060279"(positive regulation of ovulation)|go:"GO:0060298"(positive regulation of sarcomere organization)|interpro:IPR002928(Myosin tail)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|refseq:NP_001129763.1|wormbase:F07A5.7b|dip:DIP-24443N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2017/02/23 rogid:G/tGsp4WwyIUGdFnfOzoBMkgOrM6239 rogid:qDSWRA42Ad8ZvgnKN1TomAfe1f46239 intact-crc:106AB52942C1DCAB|rigid:qZJBGTT67TIPpgw09jLfMNhPTcg false - sufficient binding region:508-872("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECX8 uniprotkb:Q9BL83 intact:EBI-313610|ensemblmetazoa:K10C8.3a.1|ensemblmetazoa:K10C8.3a.2 intact:EBI-2005777|ensemblmetazoa:Y34D9A.10.1 psi-mi:g5ecx8_caeel(display_long)|uniprotkb:istr-1(gene name)|psi-mi:istr-1(display_short)|uniprotkb:CELE_K10C8.3(orf name)|uniprotkb:K10C8.3(orf name) psi-mi:q9bl83_caeel(display_long)|uniprotkb:vps-4(gene name)|psi-mi:vps-4(display_short)|uniprotkb:CELE_Y34D9A.10(orf name)|uniprotkb:Y34D9A.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460821|imex:IM-11985-510 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q21414(uniprot-removed-ac)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|refseq:NP_506170.2|ensemblmetazoa:K10C8.3a.1(transcript)|ensemblmetazoa:K10C8.3a.2(transcript)|ensemblmetazoa:WBGene00010736(gene)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|interpro:IPR042277|wormbase:K10C8.3a|reactome:R-CEL-6798695|reactome:R-CEL-9668328 refseq:NP_490816.4|wormbase:Y34D9A.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|interpro:IPR036181|reactome:R-CEL-9668328|interpro:IPR031255|ensemblmetazoa:WBGene00021334(gene)|ensemblmetazoa:Y34D9A.10.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007033"(vacuole organization)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0016197"(endosomal transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903539"(protein localization to postsynaptic membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OGyFRpQwxAeJGJo1JiLtw/DD0006239 rogid:b93R1ndEtzzHaOF6Gv3G7NwLxAw6239 intact-crc:D313B9175CA565E6|rigid:7nXX9YD7ZpgdprPhWi2jiiVsEa8 false sufficient binding region:185-445("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45148 uniprotkb:O61199 intact:EBI-2005352|ensemblmetazoa:W02F12.5.1 intact:EBI-2005348|ensemblmetazoa:T22B11.5a.1 psi-mi:o45148_caeel(display_long)|uniprotkb:dlst-1(gene name)|psi-mi:dlst-1(display_short)|uniprotkb:E2K(gene name synonym)|uniprotkb:CELE_W02F12.5(orf name)|uniprotkb:W02F12.5(orf name) psi-mi:odo1_caeel(display_long)|uniprotkb:ogdh-1(gene name)|psi-mi:ogdh-1(display_short)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:T22B11.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460811|imex:IM-11985-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504700.2|wormbase:W02F12.5|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|reactome:R-CEL-71064|reactome:R-CEL-389661|interpro:IPR023213|reactome:R-CEL-71403|ensemblmetazoa:W02F12.5.1(transcript)|ensemblmetazoa:WBGene00020950(gene)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0045252"(oxoglutarate dehydrogenase complex) refseq:NP_500617.1|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|reactome:R-CEL-71064|reactome:R-CEL-389661|interpro:IPR031717|interpro:IPR032106|interpro:IPR029061|wormbase:T22B11.5a|interpro:IPR042179|reactome:R-CEL-71403|ensemblmetazoa:T22B11.5a.1(transcript)|ensemblmetazoa:WBGene00020679(gene)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0045252"(oxoglutarate dehydrogenase complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Rpl8XUxHB+61hotybaiZR/1GJBI6239 rogid:iL8Id30CEzB4B79YD4QupBK+BeE6239 intact-crc:6794B0536B04CED2|rigid:Lt5u21tbfj0OfnZ/nVW9wkvTQ1s false sufficient binding region:186-463("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RT11 uniprotkb:Q19088 intact:EBI-6458195|ensemblmetazoa:B0511.9c.1|uniprotkb:A9D8E6|uniprotkb:G4RT06|uniprotkb:H2KYB5 intact:EBI-318878|ensemblmetazoa:F01F1.4.1|ensemblmetazoa:F01F1.4.2 psi-mi:cdc26_caeel(display_long)|uniprotkb:Cell division cycle protein 26 homolog(gene name synonym)|uniprotkb:mat-4(gene name synonym)|uniprotkb:tag-265(gene name synonym)|uniprotkb:B0511.9(orf name)|uniprotkb:cdc-26(gene name)|psi-mi:cdc-26(display_short) psi-mi:q19088_caeel(display_long)|uniprotkb:rabn-5(gene name)|psi-mi:rabn-5(display_short)|uniprotkb:F01F1.4(orf name)|uniprotkb:CELE_F01F1.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460831|imex:IM-11985-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:B0511.9c.1(transcript)|ensemblmetazoa:WBGene00015235(gene)|go:"GO:0005634"(nucleus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:B0511.9a|wormbase:B0511.9b|wormbase:B0511.9d|refseq:NP_001251445.1|refseq:NP_740913.3|refseq:NP_740914.2|refseq:NP_001251447.1|wormbase:B0511.9c|dip:DIP-26086N refseq:NP_498266.1|wormbase:F01F1.4|ensemblmetazoa:F01F1.4.1(transcript)|ensemblmetazoa:F01F1.4.2(transcript)|ensemblmetazoa:WBGene00017161(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006897"(endocytosis)|go:"GO:0018996"(molting cycle, collagen and cuticulin-based cuticle)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003914(Rabaptin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015390(Rabaptin, GTPase-Rab5 binding)|interpro:IPR017455(Zinc finger, FYVE-related)|dip:DIP-26972N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:4EiUm/eby0CTOnoyalmBYdJZmOE6239 rogid:rDx7/0HyFYJBplCfN/XYyNIxtXs6239 intact-crc:7FF0093A76014353|rigid:P0yKFpHL4YnGE5UOCw0DoWSK+TQ false - sufficient binding region:18-414("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34371 uniprotkb:O01501-1 intact:EBI-315422|ensemblmetazoa:C50C3.8.1 intact:EBI-6457824|ensemblmetazoa:C37A2.4a.1 psi-mi:bat42_caeel(display_long)|uniprotkb:C50C3.8(orf name)|uniprotkb:bath-42(gene name)|psi-mi:bath-42(display_short) psi-mi:o01501-1(display_long)|uniprotkb:C37A2.4(orf name)|uniprotkb:cye-1(gene name)|psi-mi:cye-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460841|imex:IM-11985-512 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498784.1|wormbase:C50C3.8|ensemblmetazoa:C50C3.8.1(transcript)|ensemblmetazoa:WBGene00016803(gene)|go:"GO:0005634"(nucleus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|reactome:R-CEL-5632684|dip:DIP-26215N ensemblmetazoa:C37A2.4a.1(transcript)|ensemblmetazoa:WBGene00000871(gene)|intact:EBI-6499833(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:uc+qR6fPukN9TqRpxGtw9O6Qz906239 rogid:THl5Hcv1lfLuT3xEXRZhEQm1+886239 intact-crc:EE19750114F32C6F|rigid:38Pyav8NLP1wWUXP0rX8ery9PnU false sufficient binding region:18-410("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:Q9BKT9 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-2005827|ensemblmetazoa:Y37E3.15a.1 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:q9bkt9_caeel(display_long)|uniprotkb:npp-13(gene name)|psi-mi:npp-13(display_short)|uniprotkb:CELE_Y37E3.15(orf name)|uniprotkb:Y37E3.15(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460851|imex:IM-11985-513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N interpro:IPR007231(Nucleoporin interacting component)|refseq:NP_740802.1|wormbase:Y37E3.15a|ensemblmetazoa:WBGene00003799(gene)|ensemblmetazoa:Y37E3.15a.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1903379"(regulation of mitotic chromosome condensation)|go:"GO:1990893"(mitotic chromosome centromere condensation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:KQxxaQPFCk9tycEeORD/MJg0krY6239 intact-crc:7652C958BABA2893|rigid:XP/j9xltnjAZ0r0DwdKgd8vz5bo false sufficient binding region:18-404("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4N3 uniprotkb:P91001 intact:EBI-2001892|ensemblmetazoa:B0240.4.1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:ndc1_caeel(display_long)|uniprotkb:npp-22(gene name)|psi-mi:npp-22(display_short)|uniprotkb:ndc-1(gene name synonym)|uniprotkb:Nucleoporin npp-22(gene name synonym)|uniprotkb:B0240.4(orf name) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460861|imex:IM-11985-514 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019049|refseq:NP_505962.2|wormbase:B0240.4|ensemblmetazoa:B0240.4.1(transcript)|ensemblmetazoa:WBGene00007118(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0070762"(nuclear pore transmembrane ring) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KuCRg4LRvvi9IvVwANYKxKY9RC86239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:59D1A3302AEF40F5|rigid:72cSGPyPy6UgYKfx1wyFm8MxJ+Q false - sufficient binding region:18-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09248 uniprotkb:P91001 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460871|imex:IM-11985-515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:7B40969E80202E65|rigid:oJB4pxa4JvkRoynl2Jg9oxjvwI0 false - sufficient binding region:18-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:Q18508 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-2002730|ensemblmetazoa:C38D4.3.1 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:mel28_caeel(display_long)|uniprotkb:mel-28(gene name)|psi-mi:mel-28(display_short)|uniprotkb:Maternal effect lethal protein 28(gene name synonym)|uniprotkb:C38D4.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460881|imex:IM-11985-516 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 refseq:NP_497987.2|wormbase:C38D4.3|ensemblmetazoa:C38D4.3.1(transcript)|ensemblmetazoa:WBGene00003210(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060090"(molecular adaptor activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:UEMa5/rs0WbLvnqlwj+dYCYc6qI6239 intact-crc:99800446017750C4|rigid:RM8LRlMFSHEo+/TTiH8J1Z8lVx0 false sufficient binding region:18-368("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:Q9XVP0 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460891|imex:IM-11985-517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 intact-crc:0E1FA1CC6762B500|rigid:1pUFNYCVb1jbzzEdfwTbk/pt+aY false sufficient binding region:18-368("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91349 uniprotkb:P91001 intact:EBI-322479|ensemblmetazoa:F56A3.4.1|ensemblmetazoa:F56A3.4.2 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:spd5_caeel(display_long)|uniprotkb:spd-5(gene name)|psi-mi:spd-5(display_short)|uniprotkb:F56A3.4(orf name) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460901|imex:IM-11985-518 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491539.1|wormbase:F56A3.4|ensemblmetazoa:F56A3.4.1(transcript)|ensemblmetazoa:F56A3.4.2(transcript)|ensemblmetazoa:WBGene00004955(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008104"(protein localization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0098882"(structural constituent of presynaptic active zone)|dip:DIP-24727N refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:xPJgQOxl9/vnW1nkJsXfAxURs046239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:0A4753163D80A742|rigid:N9UwleEtwKoFWwAq/BusZhDzT50 false - sufficient binding region:18-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34509 uniprotkb:P91001 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460911|imex:IM-11985-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:92A6F32D9B2D1736|rigid:XcqXXQvWuLHr0UK8wC2kaqSJfkI false - sufficient binding region:18-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21295 uniprotkb:P91001 intact:EBI-2004307|uniprotkb:Q21296|ensemblmetazoa:K07F5.13a.1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:q21295_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460921|imex:IM-11985-520 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501772.1|wormbase:K07F5.13a|interpro:IPR024864|interpro:IPR025712|ensemblmetazoa:K07F5.13a.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CgqZPl+7gsTQJxOMbCCLLuEiUh46239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:138604A6F550514F|rigid:RuVt9cMREzcCoFiQ7ExWeuItWtI false - sufficient binding region:18-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:Q09601-1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460931|imex:IM-11985-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:2C4D17DE5B06F474|rigid:oHelW5QIfQxjihryv+aR01HCCm0 false sufficient binding region:18-368("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NDC9 uniprotkb:P91001 intact:EBI-2004982|uniprotkb:O45742|ensemblmetazoa:T03F6.5.1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:lis1_caeel(display_long)|uniprotkb:pnm-1(gene name synonym)|uniprotkb:Pronuclear migration abnormal protein 1(gene name synonym)|uniprotkb:T03F6.5(orf name)|uniprotkb:lis-1(gene name)|psi-mi:lis-1(display_short) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460941|imex:IM-11985-522 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_499755.1|wormbase:T03F6.5|interpro:IPR017252(Dynein regulator)|interpro:IPR020472|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|reactome:R-CEL-6811436|interpro:IPR036322|interpro:IPR037190|ensemblmetazoa:T03F6.5.1(transcript)|ensemblmetazoa:WBGene00003047(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005818"(aster)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007281"(germ cell development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0040011"(locomotion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070840"(dynein complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:QdvWBwu6LtFK8AkjBexVkZtwO1M6239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:B75D19121F33320C|rigid:+Kez7AaeEHFH94Utv3CM1E6KcSg false - sufficient binding region:18-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34563 uniprotkb:P91001 intact:EBI-327278|ensemblmetazoa:T05G5.10a.1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:if5a1_caeel(display_long)|uniprotkb:iff-1(gene name)|psi-mi:iff-1(display_short)|uniprotkb:T05G5.10(orf name)|uniprotkb:Initiation factor five protein 1(gene name synonym) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460951|imex:IM-11985-523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001255021.1|refseq:NP_001255020.1|wormbase:T05G5.10a|reactome:R-CEL-204626|ensemblmetazoa:T05G5.10a.1(transcript)|ensemblmetazoa:WBGene00002064(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0007276"(gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|go:"GO:0005737"(cytoplasm)|dip:DIP-25111N refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ew1bTZgD4xTVQM92D5AvNdLqTig6239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:E49DC4356E24BFC9|rigid:dLIj2BfDuypA24USViJG+9fO56k false - sufficient binding region:18-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91001 uniprotkb:Q9N4A7-1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 intact:EBI-6456140|ensemblmetazoa:Y77E11A.13a.1 psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:q9n4a7-1(display_long)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:Nuclear pore complex protein 20(gene name synonym)|uniprotkb:npp-20(gene name)|psi-mi:npp-20(display_short)|uniprotkb:CeSec13R(gene name synonym)|uniprotkb:sec-13(gene name synonym)|uniprotkb:Y77E11A.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460971|imex:IM-11985-525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 intact:EBI-318290(isoform-parent)|ensemblmetazoa:WBGene00003806(gene)|ensemblmetazoa:Y77E11A.13a.1(transcript) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 rogid:ZKmmnaa7DFkQzBBKNad56Ic7GvI6239 intact-crc:D540B2C2970F87C4|rigid:pkN1u1u0Ofh2PteVjH2gcZw6w/A false sufficient binding region:18-368("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:P91001 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-313007|ensemblmetazoa:B0547.1.1 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:csn5_caeel(display_long)|uniprotkb:B0547.1(orf name)|uniprotkb:JAB1 homolog(gene name synonym)|uniprotkb:csn-5(gene name)|psi-mi:csn-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460961|imex:IM-11985-524 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N refseq:NP_500841.1|wormbase:B0547.1|ensemblmetazoa:B0547.1.1(transcript)|ensemblmetazoa:WBGene00000817(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000338"(protein deneddylation)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008406"(gonad development)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR037518|interpro:IPR037740|go:"GO:0031672"(A band)|interpro:IPR040961|reactome:R-CEL-8951664|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-26100N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:t3h31m6yjUo0eWM3WtvGgCWlmUo6239 intact-crc:3AB5B89D490FA056|rigid:YnUlm4Ldbvp+UD79T8U0k3pkLQ4 false - sufficient binding region:18-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5W1 uniprotkb:Q65XX1 intact:EBI-360399 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:q9n5w1_caeel(display_long)|uniprotkb:C51G7.4(gene name)|psi-mi:C51G7.4(display_short) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460991|imex:IM-11985-527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:/Z/hZ0BAAbzdE9XTRSn+ojXmOIk6239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:484C11122EE9D9E8|rigid:96P7u2oGXGWSUZv4V6leG4QnWKM false sufficient binding region:179-579("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2X0 uniprotkb:Q93233 intact:EBI-2002345|ensemblmetazoa:Y113G7B.17.1|ensemblmetazoa:Y113G7B.17.2 intact:EBI-313525|ensemblmetazoa:C17E4.5.1 psi-mi:anm1_caeel(display_long)|uniprotkb:prmt-1(gene name)|psi-mi:prmt-1(display_short)|uniprotkb:epg-11(gene name synonym)|uniprotkb:Y113G7B.17(orf name) psi-mi:q93233_caeel(display_long)|uniprotkb:pabp-2(gene name)|psi-mi:pabp-2(display_short)|uniprotkb:CELE_C17E4.5(orf name)|uniprotkb:C17E4.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6460981|imex:IM-11985-526 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_507909.1|wormbase:Y113G7B.17|interpro:IPR025799|reactome:R-CEL-3214858|reactome:R-CEL-9018519|interpro:IPR029063|reactome:R-CEL-8936459|ensemblmetazoa:WBGene00013766(gene)|ensemblmetazoa:Y113G7B.17.1(transcript)|ensemblmetazoa:Y113G7B.17.2(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0009411"(response to UV)|go:"GO:0010286"(heat acclimation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042594"(response to starvation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1905909"(regulation of dauer entry) reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|refseq:NP_492504.1|wormbase:C17E4.5|ensemblmetazoa:C17E4.5.1(transcript)|ensemblmetazoa:WBGene00003904(gene)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|dip:DIP-26233N|reactome:R-CEL-73856 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vQ5Lu7GVWwHs9NAHViHLsUZtT0I6239 rogid:UQ8eYmFDtdGomnt6MTsw6TJaLno6239 intact-crc:93DA61F52A0D3D34|rigid:2m4IoBicVLHSMlu025MBPLRihxc false sufficient binding region:18-348("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:O01585 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2004403|ensemblmetazoa:K09H11.3.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:o01585_caeel(display_long)|uniprotkb:CELE_K09H11.3(orf name)|uniprotkb:rga-3(gene name)|psi-mi:rga-3(display_short)|uniprotkb:K09H11.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461001|imex:IM-11985-528 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_504503.1|wormbase:K09H11.3|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR042869|ensemblmetazoa:K09H11.3.1(transcript)|ensemblmetazoa:WBGene00019600(gene)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005813"(centrosome)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:OmLo3eyH9KRRr+1RpDnLNNzl2Zs6239 intact-crc:2B0A05118FA3C860|rigid:NpMrlXa5knf1TCO3HmKH1OH9ydA false sufficient binding region:1-774("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34509 uniprotkb:P34604 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 intact:EBI-313831|ensemblmetazoa:ZK1098.4.1 psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:ei2ba_caeel(display_long)|uniprotkb:ZK1098.4(orf name)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461011|imex:IM-11985-529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) reactome:R-CEL-72731|refseq:NP_499106.1|wormbase:ZK1098.4|ensemblmetazoa:WBGene00014221(gene)|ensemblmetazoa:ZK1098.4.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|dip:DIP-26550N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 rogid:1RBLZL4hmLKImQHEq4lbR3UkrGo6239 intact-crc:F67666190899361E|rigid:/SGUvz8qqp0IA8X9qOaxXBxxV0I false - sufficient binding region:17-305("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XW13 uniprotkb:O61955-1 intact:EBI-330111|ensemblmetazoa:Y18D10A.8.1 intact:EBI-6456691|ensemblmetazoa:B0348.6b.1|ensemblmetazoa:B0348.6b.2 psi-mi:mxt_caeel(display_long)|uniprotkb:mxt-1(gene name)|psi-mi:mxt-1(display_short)|uniprotkb:mxt(gene name synonym)|uniprotkb:Y18D10A.8(orf name) psi-mi:o61955-1(display_long)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:B0348.6(orf name)|uniprotkb:ife-3(gene name)|psi-mi:ife-3(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461021|imex:IM-11985-530 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493246.1|wormbase:Y18D10A.8|dip:DIP-27212N|ensemblmetazoa:WBGene00012478(gene)|ensemblmetazoa:Y18D10A.8.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1901190"(regulation of formation of translation initiation ternary complex)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR036612|interpro:IPR040160|rcsb pdb:5ABX|rcsb pdb:5ABY intact:EBI-330119(isoform-parent)|ensemblmetazoa:B0348.6b.1(transcript)|ensemblmetazoa:B0348.6b.2(transcript)|ensemblmetazoa:WBGene00002061(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:/y++melV76s+dfHCXyES95JOpl46239 rogid:444BHWm5Eiqg+MUqKRgLhbVaxUo6239 intact-crc:70733120E9392707|rigid:tjLDrzDGW8o1Y++lOtWp2fqh0Zk false sufficient binding region:171-507("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:P34509 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461041|imex:IM-11985-532 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 intact-crc:43AD986FEAAFC938|rigid:cPZ50rkPn61qQhX0u6Jea4c9avI false sufficient binding region:1-706("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:P39745-1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461031|imex:IM-11985-531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 intact-crc:EF82CC1E0B60A99C|rigid:3kSQMGlFhu9f6DSqGbMKGsQbzwQ false sufficient binding region:1-706("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:G5ECY0 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461061|imex:IM-11985-534 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:D1D6C57A06EE3C4C|rigid:nqUnCabNJBiG8SDXjvKFKuYJ+2M false - sufficient binding region:1-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30642 uniprotkb:Q9XVU8 intact:EBI-311981|ensemblmetazoa:R08D7.3.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:eif3d_caeel(display_long)|uniprotkb:R08D7.3(orf name)|uniprotkb:eif-3.D(gene name)|psi-mi:eif-3.D(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461051|imex:IM-11985-533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72649|ensemblmetazoa:R08D7.3.1(transcript)|ensemblmetazoa:WBGene00001227(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|refseq:NP_498984.1|wormbase:R08D7.3|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|dip:DIP-25819N ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CvW4IPXX62lvTWXOvGSZttuD3cs6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:C05C12645C807094|rigid:xx8mg2rdCOot5ugZJCbeT02thpw false - sufficient binding region:1-706("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44761 uniprotkb:Q9U2Q9 intact:EBI-2005221|ensemblmetazoa:T12F5.1.1 intact:EBI-330089|uniprotkb:Q9Y0C2|ensemblmetazoa:Y18D10A.5.1 psi-mi:o44761_caeel(display_long)|uniprotkb:sld-2(gene name)|psi-mi:sld-2(display_short)|uniprotkb:CELE_T12F5.1(orf name)|uniprotkb:T12F5.1(orf name) psi-mi:gsk3_caeel(display_long)|uniprotkb:gsk-3(gene name)|psi-mi:gsk-3(display_short)|uniprotkb:sgg-1(gene name synonym)|uniprotkb:Y18D10A.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461081|imex:IM-11985-536 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491210.1|wormbase:T12F5.1|ensemblmetazoa:T12F5.1.1(transcript)|ensemblmetazoa:WBGene00020466(gene) refseq:NP_493243.1|wormbase:Y18D10A.5|mint:Q9U2Q9|dip:DIP-25216N|ensemblmetazoa:WBGene00001746(gene)|ensemblmetazoa:Y18D10A.5.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060069"(Wnt signaling pathway, regulating spindle positioning)|go:"GO:0070986"(left/right axis specification)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-CEL-195253|reactome:R-CEL-196299|reactome:R-CEL-3371453|reactome:R-CEL-399956|reactome:R-CEL-4641262 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aGo4EtKYh8jY3ceq8kjre/Kwqws6239 rogid:nP6ix+jIij252trr3joE6r80xYo6239 intact-crc:ED77540F3AF18934|rigid:6vYC19KEDreeT5RgrHfq8mZpr2E false sufficient binding region:166-249("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:G5ECY0 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461071|imex:IM-11985-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 intact-crc:7D9F22628E303298|rigid:JUS/AgCcPOSLZJ+SPqeylv9Y5mA false - sufficient binding region:1-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90900 uniprotkb:Q19713 intact:EBI-322249|uniprotkb:Q9GYN4|ensemblmetazoa:K05B2.3.1 intact:EBI-6458795|ensemblmetazoa:F22B5.9.1 psi-mi:ifa4_caeel(display_long)|uniprotkb:ifa-4(gene name)|psi-mi:ifa-4(display_short)|uniprotkb:K05B2.3(orf name)|uniprotkb:Intermediate filament protein A4(gene name synonym)|uniprotkb:Cel IF A4(gene name synonym) psi-mi:syfb_caeel(display_long)|uniprotkb:fars-3(gene name)|psi-mi:fars-3(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:frs-2(gene name synonym)|uniprotkb:F22B5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461091|imex:IM-11985-537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508836.5|wormbase:K05B2.3|reactome:R-CEL-4419969|ensemblmetazoa:K05B2.3.1(transcript)|ensemblmetazoa:WBGene00002052(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|dip:DIP-24430N ensemblmetazoa:F22B5.9.1(transcript)|ensemblmetazoa:WBGene00001498(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR040659|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|refseq:NP_495785.1|wormbase:F22B5.9|interpro:IPR041616 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WJwjqzr8cRtjh89itzktrj4T/0o6239 rogid:vnO3fcS4LkBf8htippBIQGUn4M06239 intact-crc:E76D9F31499A9C69|rigid:d3CemYh3+l+8g5cvo2FMCZa4zKk false sufficient binding region:165-575("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90900 uniprotkb:Q22078 intact:EBI-322249|uniprotkb:Q9GYN4|ensemblmetazoa:K05B2.3.1 intact:EBI-323051|ensemblmetazoa:T01G9.4.1|ensemblmetazoa:T01G9.4.2 psi-mi:ifa4_caeel(display_long)|uniprotkb:ifa-4(gene name)|psi-mi:ifa-4(display_short)|uniprotkb:K05B2.3(orf name)|uniprotkb:Intermediate filament protein A4(gene name synonym)|uniprotkb:Cel IF A4(gene name synonym) psi-mi:q22078_caeel(display_long)|uniprotkb:npp-2(gene name)|psi-mi:npp-2(display_short)|uniprotkb:CELE_T01G9.4(orf name)|uniprotkb:T01G9.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461101|imex:IM-11985-538 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508836.5|wormbase:K05B2.3|reactome:R-CEL-4419969|ensemblmetazoa:K05B2.3.1(transcript)|ensemblmetazoa:WBGene00002052(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|dip:DIP-24430N refseq:NP_492256.1|wormbase:T01G9.4|interpro:IPR011502(Nucleoporin, Nup85-like)|ensemblmetazoa:T01G9.4.1(transcript)|ensemblmetazoa:T01G9.4.2(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090435"(protein localization to nuclear envelope)|ensemblmetazoa:WBGene00003788(gene)|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WJwjqzr8cRtjh89itzktrj4T/0o6239 rogid:zeIaeaV7GOQHaMra/3zZ7xf75q46239 intact-crc:A36F5485736A2024|rigid:icqYFMEhQcDBeEnVzW+nr3j5kUM false sufficient binding region:165-575("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90900 uniprotkb:Q95ZQ3 intact:EBI-322249|uniprotkb:Q9GYN4|ensemblmetazoa:K05B2.3.1 intact:EBI-2004972|ensemblmetazoa:T02G5.9b.1 psi-mi:ifa4_caeel(display_long)|uniprotkb:ifa-4(gene name)|psi-mi:ifa-4(display_short)|uniprotkb:K05B2.3(orf name)|uniprotkb:Intermediate filament protein A4(gene name synonym)|uniprotkb:Cel IF A4(gene name synonym) psi-mi:q95zq3_caeel(display_long)|uniprotkb:kars-1(gene name)|psi-mi:kars-1(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:CELE_T02G5.9(orf name)|uniprotkb:T02G5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461111|imex:IM-11985-539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508836.5|wormbase:K05B2.3|reactome:R-CEL-4419969|ensemblmetazoa:K05B2.3.1(transcript)|ensemblmetazoa:WBGene00002052(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|dip:DIP-24430N refseq:NP_495454.1|wormbase:T02G5.9b|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR044136|ensemblmetazoa:T02G5.9b.1(transcript)|ensemblmetazoa:WBGene00002238(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006430"(lysyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WJwjqzr8cRtjh89itzktrj4T/0o6239 rogid:iQvw4aeBips00raW7AoVlOjdpXU6239 intact-crc:11A9339A737F5516|rigid:HGhj9uNjA7v4+DRv/2Lq/b30+bc false sufficient binding region:165-575("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVP0 uniprotkb:Q94246 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 intact:EBI-6461124|ensemblmetazoa:F57F4.3.1 psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:q94246_caeel(display_long)|uniprotkb:F57F4.3(orf name)|uniprotkb:gfi-1(gene name)|psi-mi:gfi-1(display_short)|uniprotkb:CELE_F57F4.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461121|imex:IM-11985-540 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) ensemblmetazoa:F57F4.3.1(transcript)|ensemblmetazoa:WBGene00001581(gene)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0045121"(membrane raft)|interpro:IPR002603(Protein of unknown function ET)|refseq:NP_504626.1|wormbase:F57F4.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 rogid:Dap7huO6cWZv2f48TbdB1CMIcdg6239 intact-crc:23C9DA2FA13DA197|rigid:RJcCw4nJ24ITdA9YHG/eB18i5fc false - sufficient binding region:1647-2066("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q9XVU8 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461138|imex:IM-11985-541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:AB5C4944D0AA005B|rigid:oB65gtryPj0CGZNItx7xlWmyV3g false sufficient binding region:1-645("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QC4 uniprotkb:Q9XVU8 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461148|imex:IM-11985-542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 intact-crc:E3D4FE1F19D30C18|rigid:uR6uMeRxoC0vmKZex3pDkcMsT2I false - sufficient binding region:1-645("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18115-1 uniprotkb:Q09289 intact:EBI-6461158|ensemblmetazoa:C23G10.4b.1|ensemblmetazoa:C23G10.4b.2|ensemblmetazoa:C23G10.4b.3 intact:EBI-318221|ensemblmetazoa:C56G2.7a.1 psi-mi:q18115-1(display_long)|uniprotkb:26S proteasome regulatory subunit rpn-2(gene name synonym)|uniprotkb:C23G10.4(orf name)|uniprotkb:rpn-2(gene name)|psi-mi:rpn-2(display_short) psi-mi:adrm1_caeel(display_long)|uniprotkb:rpn-13(gene name)|psi-mi:rpn-13(display_short)|uniprotkb:Proteasome non-ATPase regulatory particle-like protein 13(gene name synonym)|uniprotkb:C56G2.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461163|imex:IM-11985-543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-315899(isoform-parent)|ensemblmetazoa:C23G10.4b.1(transcript)|ensemblmetazoa:C23G10.4b.2(transcript)|ensemblmetazoa:C23G10.4b.3(transcript)|ensemblmetazoa:WBGene00004459(gene) wormbase:C56G2.7a|interpro:IPR038108|interpro:IPR038633|refseq:NP_498387.2|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|ensemblmetazoa:C56G2.7a.1(transcript)|ensemblmetazoa:WBGene00016981(gene)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|interpro:IPR044867|interpro:IPR044868 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:uedYOEOYua0UluBZQ/EpltSdYfc6239 rogid:mPhnE+LbzVyUumGvLJHsawyZkUc6239 intact-crc:C517ACDC52E89DD4|rigid:/IizO30IkRTFcomOqWx6LhhQAoA false - sufficient binding region:16-374("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10653 uniprotkb:Q9U2G4 intact:EBI-330851|ensemblmetazoa:ZC168.4.1|ensemblmetazoa:ZC168.4.2|ensemblmetazoa:ZC168.4.3|ensemblmetazoa:ZC168.4.4 intact:EBI-330810|ensemblmetazoa:Y45F10A.2.1 psi-mi:ccnb1_caeel(display_long)|uniprotkb:cyb-1(gene name)|psi-mi:cyb-1(display_short)|uniprotkb:ZC168.4(orf name) psi-mi:q9u2g4_caeel(display_long)|uniprotkb:puf-3(gene name)|psi-mi:puf-3(display_short)|uniprotkb:Y45F10A.2(orf name)|uniprotkb:CELE_Y45F10A.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461183|imex:IM-11985-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-2500257|reactome:R-CEL-176408|refseq:NP_501987.1|wormbase:ZC168.4|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR039361|interpro:IPR036915|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|ensemblmetazoa:WBGene00000865(gene)|ensemblmetazoa:ZC168.4.1(transcript)|ensemblmetazoa:ZC168.4.2(transcript)|ensemblmetazoa:ZC168.4.3(transcript)|ensemblmetazoa:ZC168.4.4(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-CEL-2299718|reactome:R-CEL-2565942|reactome:R-CEL-4419969|reactome:R-CEL-8878166|reactome:R-CEL-6804114|reactome:R-CEL-69273|reactome:R-CEL-69478 refseq:NP_502606.1|wormbase:Y45F10A.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR033133|interpro:IPR033712|ensemblmetazoa:WBGene00004239(gene)|ensemblmetazoa:Y45F10A.2.1(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010608"(posttranscriptional regulation of gene expression) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:DQ3G+FwkBrd8WAXo+plVtHz1fDY6239 rogid:lBmuPoiAgSPVf/yQpLykQPGiA3U6239 intact-crc:B06D566EB3E5FB6C|rigid:WBw3qaiLdv/KxbsyUCnoeP6u7QA false - sufficient binding region:160-445("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95008 uniprotkb:G5EFA9 intact:EBI-320441|ensemblmetazoa:F25H2.9.1 intact:EBI-6457394|ensemblmetazoa:C52D10.7.1 psi-mi:psa5_caeel(display_long)|uniprotkb:pas-5(gene name)|psi-mi:pas-5(display_short)|uniprotkb:F25H2.9(orf name) psi-mi:g5efa9_caeel(display_long)|uniprotkb:C52D10.7(orf name)|uniprotkb:skr-9(gene name)|psi-mi:skr-9(display_short)|uniprotkb:CELE_C52D10.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461173|imex:IM-11985-544 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492765.1|wormbase:F25H2.9|ensemblmetazoa:F25H2.9.1(transcript)|ensemblmetazoa:WBGene00003926(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-6798695|reactome:R-CEL-5632684|dip:DIP-24675N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 ensemblmetazoa:C52D10.7.1(transcript)|ensemblmetazoa:WBGene00004815(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_503043.1|wormbase:C52D10.7|interpro:IPR036296 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bCIpCQ1H7EOMauSeXBTk7dzlrTw6239 rogid:TCdjs4T6zXW+/6oX4z3lFH4hBKQ6239 intact-crc:CBCB3232EF9CE1B2|rigid:DwXzXq4OtczC2h+VXUeiUauiUnE false sufficient binding region:162-248("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q9N5W1 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-360399 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:q9n5w1_caeel(display_long)|uniprotkb:C51G7.4(gene name)|psi-mi:C51G7.4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461193|imex:IM-11985-546 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:/Z/hZ0BAAbzdE9XTRSn+ojXmOIk6239 intact-crc:DE0F38B1341A47DB|rigid:ms84sN41lnUZL1Bp5q4/6wm6Az0 false - sufficient binding region:159-579("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:Q9N5W1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-360399 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q9n5w1_caeel(display_long)|uniprotkb:C51G7.4(gene name)|psi-mi:C51G7.4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461203|imex:IM-11985-547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:/Z/hZ0BAAbzdE9XTRSn+ojXmOIk6239 intact-crc:26818D05FC2EE095|rigid:D6kFWPKKAsf7aEq6kUUPYJClCFM false - sufficient binding region:159-579("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21225 uniprotkb:P91457 intact:EBI-314174|ensemblmetazoa:K04G2.6.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:q21225_caeel(display_long)|uniprotkb:vacl-14(gene name)|psi-mi:vacl-14(display_short)|uniprotkb:K04G2.6(orf name)|uniprotkb:CELE_K04G2.6(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461213|imex:IM-11985-548 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492215.1|wormbase:K04G2.6|ensemblmetazoa:K04G2.6.1(transcript)|ensemblmetazoa:WBGene00010565(gene)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0070772"(PAS complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|dip:DIP-24602N refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:MeQDLdLkRT0gm1ctftVBr4XIUiA6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:C256CD0A029DD7FA|rigid:3PhvkRU7BGwGkNcEEToNZrrf9KY false sufficient binding region:157-694("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N2Z7 uniprotkb:Q95XY1 intact:EBI-317369|uniprotkb:Q95XU3|uniprotkb:V6CJJ8|uniprotkb:V6CLY4|ensemblmetazoa:Y65B4BR.4a.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:wwp1_caeel(display_long)|uniprotkb:wwp-1(gene name)|psi-mi:wwp-1(display_short)|uniprotkb:Y65B4BR.4(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461223|imex:IM-11985-549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y65B4BR.4b|wormbase:Y65B4BR.4c|wormbase:Y65B4BR.4d|refseq:NP_740775.1|wormbase:Y65B4BR.4a|ensemblmetazoa:WBGene00007009(gene)|ensemblmetazoa:Y65B4BR.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|reactome:R-CEL-1253288|reactome:R-CEL-983168|reactome:R-CEL-9013406|reactome:R-CEL-9013420|refseq:NP_001293271.1|refseq:NP_001293272.1|refseq:NP_740776.1|dip:DIP-25758N|reactome:R-CEL-2672351|reactome:R-CEL-8948751|reactome:R-CEL-5610780|reactome:R-CEL-5632684 refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PlZNO3kcb422riUzp2aLH7Xaz3E6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:C0D9FE4C992EC074|rigid:uN1K2Mgx6bP73/SKxWQCTNzoIaE false sufficient binding region:1-571("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N2Z7-2 uniprotkb:Q95XY1 intact:EBI-27000518|intact:EBI-6461233|ensemblmetazoa:Y65B4BR.4b.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:q9n2z7-2(display_long)|uniprotkb:wwp-1(gene name)|psi-mi:wwp-1(display_short)|uniprotkb:Y65B4BR.4(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461238|imex:IM-11985-550 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-317369(isoform-parent)|ensemblmetazoa:WBGene00007009(gene)|ensemblmetazoa:Y65B4BR.4b.1(transcript) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2021/06/18 rogid:pGVx+j7T4Od4UrrF0/25wYs6H706239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:417F0B953BE0452C|rigid:xzJRDiYUkwpWjvSCF7To2tyrEL0 false sufficient binding region:1-568("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54812 uniprotkb:P54811 intact:EBI-320265|uniprotkb:Q18560|ensemblmetazoa:C41C4.8.1|ensemblmetazoa:C41C4.8.2 intact:EBI-320245|ensemblmetazoa:C06A1.1.1 psi-mi:tera2_caeel(display_long)|uniprotkb:C41C4.8(orf name)|uniprotkb:Cell division cycle-related protein 48.2(gene name synonym)|uniprotkb:p97/CDC48 homolog 2(gene name synonym)|uniprotkb:cdc-48.2(gene name)|psi-mi:cdc-48.2(display_short) psi-mi:tera1_caeel(display_long)|uniprotkb:C06A1.1(orf name)|uniprotkb:Cell division cycle-related protein 48.1(gene name synonym)|uniprotkb:p97/CDC48 homolog 1(gene name synonym)|uniprotkb:cdc-48.1(gene name)|psi-mi:cdc-48.1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461258|imex:IM-11985-552 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495705.1|wormbase:C41C4.8|ensemblmetazoa:C41C4.8.1(transcript)|ensemblmetazoa:C41C4.8.2(transcript)|ensemblmetazoa:WBGene00008053(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|reactome:R-CEL-3371511|reactome:R-CEL-9013407|reactome:R-CEL-110320|reactome:R-CEL-6798695|reactome:R-CEL-382556|reactome:R-CEL-532668|reactome:R-CEL-5689877|dip:DIP-26566N|reactome:R-CEL-8876725|reactome:R-CEL-5358346 refseq:NP_496273.1|wormbase:C06A1.1|ensemblmetazoa:C06A1.1.1(transcript)|ensemblmetazoa:WBGene00007352(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|dip:DIP-26650N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:8orzUPvtC7n65UHKceyBId+MP0Q6239 rogid:VgGB6CuL6hJaCop1MLkdaQAjhCE6239 intact-crc:2228BDF3B547A7A4|rigid:znN7+PS+lD4NnOKTHrruTV6ymy8 false - sufficient binding region:156-470("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q9N2Z7-2 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-27000518|intact:EBI-6461233|ensemblmetazoa:Y65B4BR.4b.1 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q9n2z7-2(display_long)|uniprotkb:wwp-1(gene name)|psi-mi:wwp-1(display_short)|uniprotkb:Y65B4BR.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461248|imex:IM-11985-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) intact:EBI-317369(isoform-parent)|ensemblmetazoa:WBGene00007009(gene)|ensemblmetazoa:Y65B4BR.4b.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2021/06/18 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:pGVx+j7T4Od4UrrF0/25wYs6H706239 intact-crc:4604BBCBDB2470D6|rigid:y1G5lMIozyLVEpYGC+D95D77k6o false - sufficient binding region:1-568("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q4JFH9 uniprotkb:Q9BL83 intact:EBI-2007536|intact:EBI-13873459|uniprotkb:Q09636|uniprotkb:Q4JFI0|uniprotkb:Q95ZX9|uniprotkb:S6FD32|ensemblmetazoa:C27D6.4c.1 intact:EBI-2005777|ensemblmetazoa:Y34D9A.10.1 psi-mi:crh2_caeel(display_long)|uniprotkb:C27D6.4(orf name)|uniprotkb:crh-2(gene name)|psi-mi:crh-2(display_short) psi-mi:q9bl83_caeel(display_long)|uniprotkb:vps-4(gene name)|psi-mi:vps-4(display_short)|uniprotkb:CELE_Y34D9A.10(orf name)|uniprotkb:Y34D9A.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461268|imex:IM-11985-553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C27D6.4b|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|refseq:NP_740987.4|wormbase:C27D6.4a|wormbase:C27D6.4c|wormbase:C27D6.4d|ensemblmetazoa:C27D6.4c.1(transcript)|ensemblmetazoa:WBGene00016162(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035497"(cAMP response element binding) refseq:NP_490816.4|wormbase:Y34D9A.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|interpro:IPR036181|reactome:R-CEL-9668328|interpro:IPR031255|ensemblmetazoa:WBGene00021334(gene)|ensemblmetazoa:Y34D9A.10.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007033"(vacuole organization)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0016197"(endosomal transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903539"(protein localization to postsynaptic membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2021/11/30 rogid:MZUMx2dPPBLev/xJZHDsWW+QfLE6239 rogid:b93R1ndEtzzHaOF6Gv3G7NwLxAw6239 intact-crc:E72937C05E78E633|rigid:0Bt8wa4YklqA05Q7cGl0OI8CyPM false sufficient binding region:176-351("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECR7 intact:EBI-6461281 intact:EBI-330567|ensemblmetazoa:Y41C4A.10.1 - psi-mi:g5ecr7_caeel(display_long)|uniprotkb:3L686(gene name synonym)|uniprotkb:elb-1(gene name)|psi-mi:elb-1(display_short)|uniprotkb:Y41C4A.10(orf name)|uniprotkb:CELE_Y41C4A.10(orf name) psi-mi:g5ee95_caeel(display_short)|psi-mi:EBI-6461281(display_long)|uniprotkb:agef-1(gene name)|psi-mi:agef-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461278|imex:IM-11985-554 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9XWU4(uniprot-removed-ac)|refseq:NP_499517.1|reactome:R-CEL-674695|reactome:R-CEL-6796648|wormbase:Y41C4A.10|interpro:IPR039049|interpro:IPR029071|reactome:R-CEL-1234176|reactome:R-CEL-983168|reactome:R-CEL-8951664|ensemblmetazoa:WBGene00001235(gene)|ensemblmetazoa:Y41C4A.10.1(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|reactome:R-CEL-75955|reactome:R-CEL-112382 uniprotkb:G5EE95(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:nd6q1xH1t5OIdfLT3hHtTS3gTqU6239 rogid:ANZ5/daaKLwqLU21jN4cfdBrbl46239 intact-crc:46CB41FEF7489E4E|rigid:ZDp7RD3juJ15dZA380ImoAX1USA false - sufficient binding region:1538-1628("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44451 uniprotkb:Q19749 intact:EBI-326559|ensemblmetazoa:C04C3.3.1 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 psi-mi:odpb_caeel(display_long)|uniprotkb:pdhb-1(gene name)|psi-mi:pdhb-1(display_short)|uniprotkb:C04C3.3(orf name) psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461294|imex:IM-11985-555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500340.1|wormbase:C04C3.3|ensemblmetazoa:C04C3.3.1(transcript)|ensemblmetazoa:WBGene00015413(gene)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|reactome:R-CEL-204174|reactome:R-CEL-389661|reactome:R-CEL-5362517|reactome:R-CEL-70268|dip:DIP-24348N refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:spzNGWMMdyxgQ7syaPnZr0lXV/k6239 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 intact-crc:A6DB01C781D8BB8E|rigid:d2hEzZnNtqFpvhhjLv2Z63CRrGQ false sufficient binding region:15-352("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVS8 uniprotkb:Q9U757 intact:EBI-2007577|ensemblmetazoa:C15H11.6.1|ensemblmetazoa:C15H11.6.2 intact:EBI-2006451|ensemblmetazoa:Y71F9AM.5a.1 psi-mi:nxf2_caeel(display_long)|uniprotkb:nxf-2(gene name)|psi-mi:nxf-2(display_short)|uniprotkb:nfx-2(gene name synonym)|uniprotkb:C15H11.6(orf name) psi-mi:nxt1_caeel(display_long)|uniprotkb:nxt-1(gene name)|psi-mi:nxt-1(display_short)|uniprotkb:nxt1(gene name synonym)|uniprotkb:Y71F9AM.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461304|imex:IM-11985-556 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032675|interpro:IPR032710|interpro:IPR030217|wormbase:C15H11.6|interpro:IPR018222|rcsb pdb:3NV0|reactome:R-CEL-159236|refseq:NP_506568.2|ensemblmetazoa:C15H11.6.1(transcript)|ensemblmetazoa:C15H11.6.2(transcript)|ensemblmetazoa:WBGene00003835(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus") refseq:NP_491077.1|wormbase:Y71F9AM.5a|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:3NV0|reactome:R-CEL-159236|ensemblmetazoa:WBGene00003836(gene)|ensemblmetazoa:Y71F9AM.5a.1(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2021/11/30 rogid:pPXsE5o5J3Jb2kpMmPqc2KmkqjI6239 rogid:BqzepUMVjiGYWzYv33tbIuf+o3o6239 intact-crc:8B805530EB988C7A|rigid:u5UdybUFxblnzwm4fsBxv3aL9bo false sufficient binding region:137-405("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TA83 uniprotkb:P39745-1 intact:EBI-331999|uniprotkb:P34408|uniprotkb:Q95QJ6|ensemblmetazoa:F22B7.5a.1 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 psi-mi:dnj10_caeel(display_long)|uniprotkb:F22B7.5(orf name)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short) psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461314|imex:IM-11985-557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498901.1|refseq:NP_498902.1|wormbase:F22B7.5a|wormbase:F22B7.5b|dip:DIP-24664N|ensemblmetazoa:F22B7.5a.1(transcript)|ensemblmetazoa:WBGene00001028(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009408"(response to heat)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:rZSB2nN04hE44ryl282RwGo9QqQ6239 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 intact-crc:EBDEA8640D0899DD|rigid:81PRdkoKBj088o0twLMlGP2zLT8 false sufficient binding region:151-401("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95Y13 uniprotkb:Q8TA83 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 intact:EBI-331999|uniprotkb:P34408|uniprotkb:Q95QJ6|ensemblmetazoa:F22B7.5a.1 psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:dnj10_caeel(display_long)|uniprotkb:F22B7.5(orf name)|uniprotkb:DnaJ domain protein 10(gene name synonym)|uniprotkb:dnj-10(gene name)|psi-mi:dnj-10(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461324|imex:IM-11985-558 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N refseq:NP_498901.1|refseq:NP_498902.1|wormbase:F22B7.5a|wormbase:F22B7.5b|dip:DIP-24664N|ensemblmetazoa:F22B7.5a.1(transcript)|ensemblmetazoa:WBGene00001028(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009408"(response to heat)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 rogid:rZSB2nN04hE44ryl282RwGo9QqQ6239 intact-crc:562C8A6DE7F1248A|rigid:Tz82GUQD9fZ1OpGyBoup6Dj4dRM false - sufficient binding region:151-401("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2V0X4 uniprotkb:Q17695 intact:EBI-6456854 intact:EBI-321960|ensemblmetazoa:C06A8.5.1 psi-mi:q2v0x4_caeel(display_long)|uniprotkb:cogc-3(gene name)|psi-mi:cogc-3(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 3(gene name synonym) psi-mi:spdl1_caeel(display_long)|uniprotkb:spdl-1(gene name)|psi-mi:spdl-1(display_short)|uniprotkb:C06A8.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461334|imex:IM-11985-559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007265(Sec34-like protein) wormbase:C06A8.5|refseq:NP_495637.1|ensemblmetazoa:C06A8.5.1(transcript)|ensemblmetazoa:WBGene00015515(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1902423"(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|go:"GO:1905824"(positive regulation of mitotic sister chromatid arm separation)|dip:DIP-27271N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:G/tGsp4WwyIUGdFnfOzoBMkgOrM6239 rogid:g40O7KzMDsgC0rWt+1ukYir8zA46239 intact-crc:6A4ED3340DBC2002|rigid:uIihbpeg+yerjyJJ/Ro9StlEjcM false - sufficient binding region:151-401("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17695 uniprotkb:Q17695 intact:EBI-321960|ensemblmetazoa:C06A8.5.1 intact:EBI-321960|ensemblmetazoa:C06A8.5.1 psi-mi:spdl1_caeel(display_long)|uniprotkb:spdl-1(gene name)|psi-mi:spdl-1(display_short)|uniprotkb:C06A8.5(orf name) psi-mi:spdl1_caeel(display_long)|uniprotkb:spdl-1(gene name)|psi-mi:spdl-1(display_short)|uniprotkb:C06A8.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461354|imex:IM-11985-561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C06A8.5|refseq:NP_495637.1|ensemblmetazoa:C06A8.5.1(transcript)|ensemblmetazoa:WBGene00015515(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1902423"(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|go:"GO:1905824"(positive regulation of mitotic sister chromatid arm separation)|dip:DIP-27271N wormbase:C06A8.5|refseq:NP_495637.1|ensemblmetazoa:C06A8.5.1(transcript)|ensemblmetazoa:WBGene00015515(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1902423"(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|go:"GO:1905824"(positive regulation of mitotic sister chromatid arm separation)|dip:DIP-27271N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g40O7KzMDsgC0rWt+1ukYir8zA46239 rogid:g40O7KzMDsgC0rWt+1ukYir8zA46239 intact-crc:BC5CB0921467910F|rigid:6eoo6V82uZJriNzs5b38IsuPHhw false - sufficient binding region:151-301("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95Y13 uniprotkb:Q09601 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 intact:EBI-2004755|uniprotkb:O62340|ensemblmetazoa:R06F6.5b.1 psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:nup35_caeel(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461344|imex:IM-11985-560 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N interpro:IPR017389(Nucleoporin, NUP53)|refseq:NP_496324.1|refseq:NP_496325.1|wormbase:R06F6.5a|wormbase:R06F6.5b|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:E05EE0E60F1EA9F6|rigid:3u3M70jx9vEGhcQoqkmWf5TXatA false - sufficient binding region:151-381("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01488 uniprotkb:Q17695 intact:EBI-320537|ensemblmetazoa:C13F10.2.1 intact:EBI-321960|ensemblmetazoa:C06A8.5.1 psi-mi:o01488_caeel(display_long)|uniprotkb:kxd-1(gene name)|psi-mi:kxd-1(display_short)|uniprotkb:C13F10.2(orf name)|uniprotkb:CELE_C13F10.2(orf name) psi-mi:spdl1_caeel(display_long)|uniprotkb:spdl-1(gene name)|psi-mi:spdl-1(display_short)|uniprotkb:C06A8.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461364|imex:IM-11985-562 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504831.1|wormbase:C13F10.2|ensemblmetazoa:C13F10.2.1(transcript)|ensemblmetazoa:WBGene00015742(gene)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|dip:DIP-27148N wormbase:C06A8.5|refseq:NP_495637.1|ensemblmetazoa:C06A8.5.1(transcript)|ensemblmetazoa:WBGene00015515(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1902423"(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|go:"GO:1905824"(positive regulation of mitotic sister chromatid arm separation)|dip:DIP-27271N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZX/rck9tSHblPGJKegKAjZiqxeA6239 rogid:g40O7KzMDsgC0rWt+1ukYir8zA46239 intact-crc:7BD0F01854BA8FDE|rigid:ZSjGFroEfk8LpqcX0DV/UVKvOHY false - sufficient binding region:151-251("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:Q20641 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-327871|ensemblmetazoa:F52B10.1.1 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:q20641_caeel(display_long)|uniprotkb:nmy-1(gene name)|psi-mi:nmy-1(display_short)|uniprotkb:CELE_F52B10.1(orf name)|uniprotkb:F52B10.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461374|imex:IM-11985-563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) refseq:NP_508504.2|wormbase:F52B10.1a|reactome:R-CEL-5627123|ensemblmetazoa:F52B10.1.1(transcript)|ensemblmetazoa:WBGene00003776(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005912"(adherens junction)|go:"GO:0008104"(protein localization)|go:"GO:0016459"(myosin complex)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030016"(myofibril)|go:"GO:0032982"(myosin filament)|go:"GO:0040011"(locomotion)|go:"GO:0043292"(contractile fiber)|go:"GO:0051015"(actin filament binding)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|interpro:IPR000048(IQ calmodulin-binding region)|dip:DIP-26816N|reactome:R-CEL-445355 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:9xXqLsOZ5WsaxIIl17hcE9urWao6239 intact-crc:C092CD64B249BE17|rigid:qGsQvMS2UvT+nnPK8XdYl5XLc4Q false - sufficient binding region:1508-1963("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O45926 uniprotkb:Q8IU00 intact:EBI-330800|ensemblmetazoa:Y43E12A.1.1 intact:EBI-6456292|ensemblmetazoa:Y73B6BL.38.1 psi-mi:o45926_caeel(display_long)|uniprotkb:cyb-2.1(gene name)|psi-mi:cyb-2.1(display_short)|uniprotkb:Y43E12A.1(orf name)|uniprotkb:CELE_Y43E12A.1(orf name) psi-mi:q8iu00_caeel(display_long)|uniprotkb:Y73B6BL.38(orf name)|uniprotkb:puf-11(gene name)|psi-mi:puf-11(display_short)|uniprotkb:CELE_Y73B6BL.38(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461384|imex:IM-11985-564 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502047.1|wormbase:Y43E12A.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|reactome:R-CEL-176408|reactome:R-CEL-2500257|reactome:R-CEL-6804114|reactome:R-CEL-69273|reactome:R-CEL-69478|interpro:IPR039361|interpro:IPR036915|go:"GO:0044772"(mitotic cell cycle phase transition)|ensemblmetazoa:WBGene00000866(gene)|ensemblmetazoa:Y43E12A.1.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|reactome:R-CEL-2565942|reactome:R-CEL-4419969|reactome:R-CEL-8878166|reactome:R-CEL-2299718 ensemblmetazoa:WBGene00022257(gene)|ensemblmetazoa:Y73B6BL.38.1(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|interpro:IPR033712|interpro:IPR033133|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_741425.1|wormbase:Y73B6BL.38 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:3utXAZnYQvOH6Y+iPVRSIB8dqPw6239 rogid:ehoUpNZTukhqYuNTttotQ6vThvQ6239 intact-crc:6E5A827D4738DA29|rigid:Tpc62mL7JFI3MMXzCYYZM6TVHRw false - sufficient binding region:149-505("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U302 uniprotkb:P34341 intact:EBI-320139|ensemblmetazoa:Y106G6H.2a.1|ensemblmetazoa:Y106G6H.2a.2|ensemblmetazoa:Y106G6H.2a.3|ensemblmetazoa:Y106G6H.2a.4|ensemblmetazoa:Y106G6H.2a.5 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 psi-mi:q9u302_caeel(display_long)|uniprotkb:pab-1(gene name)|psi-mi:pab-1(display_short)|uniprotkb:CELE_Y106G6H.2(orf name)|uniprotkb:Y106G6H.2(orf name) psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461404|imex:IM-11985-566 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021709.1|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensemblmetazoa:WBGene00003902(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|ensemblmetazoa:Y106G6H.2a.1(transcript)|ensemblmetazoa:Y106G6H.2a.2(transcript)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0040026"(positive regulation of vulval development)|go:"GO:0043186"(P granule)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1905938"(positive regulation of germ cell proliferation)|go:"GO:1905941"(positive regulation of gonad development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|ensemblmetazoa:Y106G6H.2a.3(transcript)|ensemblmetazoa:Y106G6H.2a.4(transcript)|ensemblmetazoa:Y106G6H.2a.5(transcript)|go:"GO:0000932"(P-body)|wormbase:Y106G6H.2|dip:DIP-26308N|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-429947 interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:JXPsFlZzT39SeFvQ4sqLGGyReFY6239 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 intact-crc:5426450A288FEC17|rigid:inZNhGdy3a9TsED3MGLZTYfWCsI false - sufficient binding region:1-468("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95005 uniprotkb:Q19207 intact:EBI-316796|ensemblmetazoa:C36B1.4.1|ensemblmetazoa:C36B1.4.2 intact:EBI-323336|ensemblmetazoa:F08F8.2.1 psi-mi:psa7_caeel(display_long)|uniprotkb:pas-4(gene name)|psi-mi:pas-4(display_short)|uniprotkb:C36B1.4(orf name)|uniprotkb:Proteasome subunit alpha 4(gene name synonym) psi-mi:q19207_caeel(display_long)|uniprotkb:hmgr-1(gene name)|psi-mi:hmgr-1(display_short)|uniprotkb:F08F8.2(orf name)|uniprotkb:CELE_F08F8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461394|imex:IM-11985-565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5689603|reactome:R-CEL-5689880|refseq:NP_492360.1|wormbase:C36B1.4|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:C36B1.4.1(transcript)|ensemblmetazoa:C36B1.4.2(transcript)|ensemblmetazoa:WBGene00003925(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_498626.2|wormbase:F08F8.2|ensemblmetazoa:F08F8.2.1(transcript)|ensemblmetazoa:WBGene00017268(gene)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|dip:DIP-25409N|reactome:R-CEL-191273 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WWXt5jeuKRCX9WomT3Wqk45PRIc6239 rogid:n+mz8S2n9i40K01p7ZmGHnh/Bu86239 intact-crc:FBBAD0A0FA3B8889|rigid:AStxAmRdiAyfh1kmqpCwmi1nte4 false - sufficient binding region:147-499("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17391 uniprotkb:Q21443 intact:EBI-593075|uniprotkb:Q95Y32|ensemblmetazoa:Y108G3AL.1a.1|ensemblmetazoa:Y108G3AL.1a.2|ensemblmetazoa:Y108G3AL.1a.3 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:cul3_caeel(display_long)|uniprotkb:cul-3(gene name)|psi-mi:cul-3(display_short)|uniprotkb:Y108G3AL.1(orf name) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461424|imex:IM-11985-568 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-8932339|refseq:NP_503151.1|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|wormbase:Y108G3AL.1a|reactome:R-CEL-4641258|reactome:R-CEL-5632684|reactome:R-CEL-983168|reactome:R-CEL-8951664|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|reactome:R-CEL-9706019|ensemblmetazoa:WBGene00000838(gene)|ensemblmetazoa:Y108G3AL.1a.1(transcript)|ensemblmetazoa:Y108G3AL.1a.2(transcript)|ensemblmetazoa:Y108G3AL.1a.3(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0071688"(striated muscle myosin thick filament assembly) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:w5+G0uKFVdxUpQ9+JoBDqiiILew6239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:951F02FFEBDC12FE|rigid:QgsRMyPLKKb8oWRHF0KGGUYrSwc false - sufficient binding region:145-566("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19371 uniprotkb:Q9U2Z1 intact:EBI-2005696|ensemblmetazoa:F12F6.6.1 intact:EBI-2006699|ensemblmetazoa:Y113G7A.3.1 psi-mi:q19371_caeel(display_long)|uniprotkb:sec-24.1(gene name)|psi-mi:sec-24.1(display_short)|uniprotkb:CELE_F12F6.6(orf name)|uniprotkb:F12F6.6(orf name) psi-mi:q9u2z1_caeel(display_long)|uniprotkb:sec-23(gene name)|psi-mi:sec-23(display_short)|uniprotkb:CELE_Y113G7A.3(orf name)|uniprotkb:Y113G7A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461414|imex:IM-11985-567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502178.1|wormbase:F12F6.6|interpro:IPR007123(Gelsolin region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|reactome:R-CEL-204005|reactome:R-CEL-5694530|reactome:R-CEL-983170|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|ensemblmetazoa:F12F6.6.1(transcript)|ensemblmetazoa:WBGene00004755(gene)|go:"GO:0000149"(SNARE binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) reactome:R-CEL-983170|reactome:R-CEL-5694530|reactome:R-CEL-204005|refseq:NP_507877.1|wormbase:Y113G7A.3|interpro:IPR007123(Gelsolin region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|ensemblmetazoa:WBGene00004754(gene)|ensemblmetazoa:Y113G7A.3.1(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:dg1hd9LmcymwnqpcxF0TbE37fZA6239 rogid:TNoDPnGPQZoy+YFLVjfOYicIfls6239 intact-crc:C6B88B6779F486B0|rigid:4C0aMK60sDe9d7oM9sgVQ0wuw6w false - sufficient binding region:1-465("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91400 uniprotkb:G5ECG0 intact:EBI-325226|ensemblmetazoa:M01E11.6.1|ensemblmetazoa:M01E11.6.2 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:p91400_caeel(display_long)|uniprotkb:klp-15(gene name)|psi-mi:klp-15(display_short)|uniprotkb:CELE_M01E11.6(orf name)|uniprotkb:M01E11.6(orf name) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461434|imex:IM-11985-569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491633.1|wormbase:M01E11.6|ensemblmetazoa:M01E11.6.1(transcript)|ensemblmetazoa:M01E11.6.2(transcript)|ensemblmetazoa:WBGene00002225(gene)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR036961|dip:DIP-25275N interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:v5atHG+eoQTFFJTThcN6np307kw6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:D074B57DC828AF50|rigid:T3X0oaHIEh8pWoUmp28i0z5LcyI false sufficient binding region:145-297("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:Q19969 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-317340|uniprotkb:O44925|ensemblmetazoa:F32E10.4.1 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:ima3_caeel(display_long)|uniprotkb:ima-3(gene name)|psi-mi:ima-3(display_short)|uniprotkb:F32E10.4(orf name)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461444|imex:IM-11985-570 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) refseq:NP_501227.1|wormbase:F32E10.4|ensemblmetazoa:F32E10.4.1(transcript)|ensemblmetazoa:WBGene00002074(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007127"(meiosis I)|go:"GO:0007276"(gamete generation)|go:"GO:0007292"(female gamete generation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0048477"(oogenesis)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|dip:DIP-26417N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:WT7vezZFUUJSBWKoQXOmUoUD+xc6239 intact-crc:008D8069FEA35E83|rigid:8kyf4B1p0cwosAMeu6bwaCKYgKw false - sufficient binding region:144-445("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:P39745-1 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461454|imex:IM-11985-571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 intact-crc:BDB2134AEE49000D|rigid:0ZJKNfsg7JrzvOH88rKmQmM+CkY false sufficient binding region:144-351("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q20010 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461464|imex:IM-11985-572 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 intact-crc:01C8DF4107DFDC13|rigid:sO96nCkn54l8wohpMcwS1E9dlOM false - sufficient binding region:144-351("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20010 uniprotkb:Q20010-1 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 intact:EBI-6461477|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:q20010-1(display_long)|uniprotkb:F35B12.5(orf name)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461474|imex:IM-11985-573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N intact:EBI-327608(isoform-parent)|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 intact-crc:A9FC1BF602656C12|rigid:tqBtvzck6WirufrKFyhVjDpWsNs false sufficient binding region:144-301("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34331-2 uniprotkb:G5EBU5 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 intact:EBI-315617|ensemblmetazoa:C10H11.10.1 psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:g5ebu5_caeel(display_long)|uniprotkb:kca-1(gene name)|psi-mi:kca-1(display_short)|uniprotkb:1F328(orf name)|uniprotkb:CELE_C10H11.10(orf name)|uniprotkb:C10H11.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461499|imex:IM-11985-575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) uniprotkb:P91042(uniprot-removed-ac)|refseq:NP_491443.3|wormbase:C10H11.10|ensemblmetazoa:C10H11.10.1(transcript)|ensemblmetazoa:WBGene00015698(gene)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016938"(kinesin I complex)|go:"GO:0019894"(kinesin binding)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0051295"(establishment of meiotic spindle localization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:u830S0jdkV753ilx7DbxmhPocv86239 rogid:JAO+3AcrFiuPzEkm68i8Ab5s90E6239 intact-crc:E231F6B92E269814|rigid:pkLVeY1eZf/JK12hb/rsRMi/BX0 false - sufficient binding region:140-407("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22078 uniprotkb:Q20010 intact:EBI-323051|ensemblmetazoa:T01G9.4.1|ensemblmetazoa:T01G9.4.2 intact:EBI-327608|uniprotkb:G3MU16|ensemblmetazoa:F35B12.5a.1|ensemblmetazoa:F35B12.5a.2 psi-mi:q22078_caeel(display_long)|uniprotkb:npp-2(gene name)|psi-mi:npp-2(display_short)|uniprotkb:CELE_T01G9.4(orf name)|uniprotkb:T01G9.4(orf name) psi-mi:sas5_caeel(display_long)|uniprotkb:sas-5(gene name)|psi-mi:sas-5(display_short)|uniprotkb:F35B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461489|imex:IM-11985-574 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492256.1|wormbase:T01G9.4|interpro:IPR011502(Nucleoporin, Nup85-like)|ensemblmetazoa:T01G9.4.1(transcript)|ensemblmetazoa:T01G9.4.2(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090435"(protein localization to nuclear envelope)|ensemblmetazoa:WBGene00003788(gene)|reactome:R-CEL-9615933 refseq:NP_001256338.1|refseq:NP_001256339.1|wormbase:F35B12.5a|wormbase:F35B12.5c|ensemblmetazoa:F35B12.5a.1(transcript)|ensemblmetazoa:F35B12.5a.2(transcript)|ensemblmetazoa:WBGene00009385(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|rcsb pdb:4YNH|rcsb pdb:4YV4|dip:DIP-27295N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zeIaeaV7GOQHaMra/3zZ7xf75q46239 rogid:pjBmo8WluFToR876YbvTPxV/p1I6239 intact-crc:20DBDA99DCCCF83C|rigid:Fel3AfXXVkpzHIssq8Y1TLI6DWo false - sufficient binding region:144-301("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDE7 uniprotkb:Q18282 intact:EBI-324390|ensemblmetazoa:Y39G10AR.12a.1 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 psi-mi:g5ede7_caeel(display_long)|uniprotkb:tpxl-1(gene name)|psi-mi:tpxl-1(display_short)|uniprotkb:Y39G10AR.12(orf name)|uniprotkb:1C866(orf name)|uniprotkb:CELE_Y39G10AR.12(orf name) psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461519|imex:IM-11985-577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_740805.1|uniprotkb:Q95XR5(uniprot-removed-ac)|wormbase:Y39G10AR.12a|ensemblmetazoa:WBGene00021470(gene)|go:"GO:0000235"(astral microtubule)|ensemblmetazoa:Y39G10AR.12a.1(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090307"(mitotic spindle assembly) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:L8qyImbTKWJWTK7yRTb2pY3sJ1s6239 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 intact-crc:FAA29F0FBD66D65A|rigid:injt2qg/u3MVRJRUU31755ZAqBw false sufficient binding region:1-401("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21443 uniprotkb:Q21443 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 intact:EBI-314110|uniprotkb:O62127|ensemblmetazoa:DY3.2.1|ensemblmetazoa:DY3.2.2 psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:lmn1_caeel(display_long)|uniprotkb:lmn-1(gene name)|psi-mi:lmn-1(display_short)|uniprotkb:lam-1(gene name synonym)|uniprotkb:DY3.2(orf name)|uniprotkb:CeLam-1(gene name synonym)|uniprotkb:Ce-lamin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461509|imex:IM-11985-576 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N reactome:R-CEL-9013405|reactome:R-CEL-9035034|refseq:NP_492371.1|wormbase:DY3.2|ensemblmetazoa:DY3.2.1(transcript)|ensemblmetazoa:DY3.2.2(transcript)|ensemblmetazoa:WBGene00003052(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0006997"(nucleus organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0051983"(regulation of chromosome segregation)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-29640N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 rogid:LV8WvN7Tglcs/Qqc5u6RZNba9d46239 intact-crc:F7D1D70D446FEF97|rigid:NQ5pGXvJQi/H2s/cmYRVxYfguPc false - sufficient binding region:1-404("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19749 uniprotkb:Q7JP75 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 intact:EBI-2003118|ensemblmetazoa:F11H8.4b.1 psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:q7jp75_caeel(display_long)|uniprotkb:cyk-1(gene name)|psi-mi:cyk-1(display_short)|uniprotkb:CELE_F11H8.4(orf name)|uniprotkb:F11H8.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461529|imex:IM-11985-578 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N refseq:NP_741211.3|wormbase:F11H8.4b|interpro:IPR016024(Armadillo-type fold)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR010473(Diaphanous GTPase-binding)|reactome:R-CEL-8980692|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9035034|interpro:IPR042201|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6785631|reactome:R-CEL-5663220|reactome:R-CEL-6798695|ensemblmetazoa:F11H8.4b.1(transcript)|ensemblmetazoa:WBGene00000872(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035046"(pronuclear migration) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 rogid:VRB7XVK3KPNRpJiNhxVx9iPqPIg6239 intact-crc:16D7202DAEA3BC74|rigid:KmHVV3ichAHkj1EDdbhMZu5SCTA false sufficient binding region:139-507("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95YF3 uniprotkb:Q18264 intact:EBI-314525|ensemblmetazoa:C07H6.5.1 intact:EBI-314561|uniprotkb:G4S3K6|ensemblmetazoa:C27F2.8.1 psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short) psi-mi:q18264_caeel(display_long)|uniprotkb:tmem-131(gene name)|psi-mi:tmem-131(display_short)|uniprotkb:C27F2.8(orf name)|uniprotkb:CELE_C27F2.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461539|imex:IM-11985-579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N refseq:NP_498059.2|wormbase:C27F2.8|ensemblmetazoa:C27F2.8.1(transcript)|ensemblmetazoa:WBGene00016170(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022113|interpro:IPR039877|dip:DIP-26360N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239 rogid:g+UkUqScDCJzXnh97+hEX1tcxRE6239 intact-crc:79651F538611969D|rigid:hv7e1NfC6H7kEwmVVwzihZtyffA false - sufficient binding region:1375-1831("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5V3 uniprotkb:O01576 intact:EBI-320898|ensemblmetazoa:C53D5.6.1 intact:EBI-318147|ensemblmetazoa:F53F10.5.1|ensemblmetazoa:F53F10.5.2 psi-mi:q9n5v3_caeel(display_long)|uniprotkb:imb-3(gene name)|psi-mi:imb-3(display_short)|uniprotkb:CELE_C53D5.6(orf name)|uniprotkb:C53D5.6(orf name) psi-mi:o01576_caeel(display_long)|uniprotkb:npp-11(gene name)|psi-mi:npp-11(display_short)|uniprotkb:F53F10.5(orf name)|uniprotkb:CELE_F53F10.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461549|imex:IM-11985-580 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490715.1|wormbase:C53D5.6|ensemblmetazoa:C53D5.6.1(transcript)|ensemblmetazoa:WBGene00002077(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|interpro:IPR041389|interpro:IPR041653|dip:DIP-26917N wormbase:F53F10.5|refseq:NP_491232.1|ensemblmetazoa:F53F10.5.1(transcript)|ensemblmetazoa:F53F10.5.2(transcript)|ensemblmetazoa:WBGene00003797(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25053N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+DZB8n7UfeEeXcLYSkOaYJ0YUNI6239 rogid:MI7h0vaxVjYQ8SIw1bMVdk5rCl06239 intact-crc:4792FF7DFF302033|rigid:ods7A5YwvAs6iNKG1X79IYskfIc false - sufficient binding region:135-805("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFV3 uniprotkb:Q9GRZ1 intact:EBI-1187461|intact:EBI-1187509|uniprotkb:G5EDA1|ensemblmetazoa:Y48A6B.11b.1 intact:EBI-313130|ensemblmetazoa:Y59A8B.7.1 psi-mi:rsa2_caeel(display_long)|uniprotkb:Y48A6B.11(orf name)|uniprotkb:rsa-2(gene name)|psi-mi:rsa-2(display_short) psi-mi:q9grz1_caeel(display_long)|uniprotkb:ebp-1(gene name)|psi-mi:ebp-1(display_short)|uniprotkb:Y59A8B.7(orf name)|uniprotkb:CELE_Y59A8B.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461569|imex:IM-11985-582 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7YSJ2(uniprot-removed-ac)|refseq:NP_001022887.1|wormbase:Y48A6B.11b|wormbase:Y48A6B.11a|refseq:NP_001022886.1|ensemblmetazoa:WBGene00012972(gene)|ensemblmetazoa:Y48A6B.11b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0048566"(embryonic digestive tract development) refseq:NP_507526.1|wormbase:Y59A8B.7|ensemblmetazoa:WBGene00013344(gene)|ensemblmetazoa:Y59A8B.7.1(transcript)|go:"GO:0000235"(astral microtubule)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1904825"(protein localization to microtubule plus-end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|dip:DIP-25552N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2016/09/27 rogid:7PBwPJFROCL8Mv1INcviVzZGFCE6239 rogid:1bYHNpIf9F0rEpuRtNiUvEu0Zhw6239 intact-crc:4A769ADB72486226|rigid:OjCjqZNi/YMdi969YKhxslu9wVo false - sufficient binding region:135-316("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34341 uniprotkb:Q95QC4 intact:EBI-2002861|ensemblmetazoa:C29E4.2.1 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 psi-mi:kle2_caeel(display_long)|uniprotkb:kle-2(gene name)|psi-mi:kle-2(display_short)|uniprotkb:Kleisin, abnormal closure, protein 2(gene name synonym)|uniprotkb:C29E4.2(orf name) psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461559|imex:IM-11985-581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009378(Protein of unknown function DUF1032)|refseq:NP_498727.2|wormbase:C29E4.2|interpro:IPR031737|interpro:IPR031739|reactome:R-CEL-2299718|ensemblmetazoa:C29E4.2.1(transcript)|ensemblmetazoa:WBGene00016202(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation) refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZOS90OoJ17xJMhtEsG+xGxyjhQk6239 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 intact-crc:76417BB44E48F92F|rigid:W4fBTjZnOlKhfAlYCitvIpGNXqM false sufficient binding region:135-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:G5EFX8 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-2006376|ensemblmetazoa:Y56A3A.1a.1 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:g5efx8_caeel(display_long)|uniprotkb:ntl-3(gene name)|psi-mi:ntl-3(display_short)|uniprotkb:CELE_Y56A3A.1(orf name)|uniprotkb:Y56A3A.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461579|imex:IM-11985-583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|refseq:NP_001076652.1|uniprotkb:Q9U233(uniprot-removed-ac)|interpro:IPR040168|interpro:IPR038635|wormbase:Y56A3A.1a|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|ensemblmetazoa:WBGene00003826(gene)|ensemblmetazoa:Y56A3A.1a.1(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030015"(CCR4-NOT core complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:W3RWMMcuA/t1m3bzpthiE8jdNrg6239 intact-crc:98C98C784D2A868E|rigid:z+vNh2NLaP3mnS7PvrAoqL3RFXg false - sufficient binding region:135-197("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95YD5 uniprotkb:Q19905 intact:EBI-313806|ensemblmetazoa:C30F8.2.1|ensemblmetazoa:C30F8.2.2|ensemblmetazoa:C30F8.2.3 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 psi-mi:q95yd5_caeel(display_long)|uniprotkb:vha-16(gene name)|psi-mi:vha-16(display_short)|uniprotkb:CELE_C30F8.2(orf name)|uniprotkb:C30F8.2(orf name) psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461589|imex:IM-11985-584 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491515.2|wormbase:C30F8.2|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|reactome:R-CEL-77387|reactome:R-CEL-1222556|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|ensemblmetazoa:C30F8.2.1(transcript)|ensemblmetazoa:C30F8.2.2(transcript)|ensemblmetazoa:C30F8.2.3(transcript)|ensemblmetazoa:WBGene00016258(gene)|go:"GO:0005769"(early endosome)|go:"GO:0007034"(vacuolar transport)|interpro:IPR044911|interpro:IPR035067|interpro:IPR036079|reactome:R-CEL-917977|reactome:R-CEL-983712|reactome:R-CEL-9639288 refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:1GQOWcfyhwox5dRmSUc3JdSShKM6239 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 intact-crc:28C9DB966AFA1309|rigid:vD8DB+RnTEjjWarsEqhSqHTLfG4 false - sufficient binding region:1-350("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20052 uniprotkb:Q19905 intact:EBI-314913|ensemblmetazoa:F35G12.9.1|ensemblmetazoa:F35G12.9.2 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 psi-mi:apc11_caeel(display_long)|uniprotkb:apc-11(gene name)|psi-mi:apc-11(display_short)|uniprotkb:F35G12.9(orf name) psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461599|imex:IM-11985-585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497937.1|wormbase:F35G12.9|ensemblmetazoa:F35G12.9.1(transcript)|ensemblmetazoa:F35G12.9.2(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|ensemblmetazoa:WBGene00000145(gene)|dip:DIP-24995N|reactome:R-CEL-983168 refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:11SdvWjkFNUyCv4arePb6BEXKEg6239 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 intact-crc:59179B24BB3B0A95|rigid:Ot7+xNz/J2BOrLq7D6z/5WutWmA false - sufficient binding region:1-350("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19905 uniprotkb:O62333 intact:EBI-320696|ensemblmetazoa:F29F11.1.1 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 psi-mi:ugdh_caeel(display_long)|uniprotkb:sqv-4(gene name)|psi-mi:sqv-4(display_short)|uniprotkb:F29F11.1(orf name)|uniprotkb:Squashed vulva protein 4(gene name synonym) psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461609|imex:IM-11985-586 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505730.1|wormbase:F29F11.1|ensemblmetazoa:F29F11.1.1(transcript)|ensemblmetazoa:WBGene00005022(gene)|go:"GO:0000003"(reproduction)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0040025"(vulval development)|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|rcsb pdb:2O3J|rcsb pdb:6OM8|go:"GO:0002009"(morphogenesis of an epithelium)|reactome:R-CEL-173599|dip:DIP-24290N interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:yP6d0A0kGv/HF0DTgqbC9hXTg686239 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 intact-crc:D3D7F25EDB9B2918|rigid:eBaLpvIw/wBpZPlV9+nxjOtvKZ4 false sufficient binding region:1-350("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:G5EGG0 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-311986|ensemblmetazoa:K09B11.9a.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:g5egg0_caeel(display_long)|uniprotkb:uso-1(gene name)|psi-mi:uso-1(display_short)|uniprotkb:K09B11.9(orf name)|uniprotkb:CELE_K09B11.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461619|imex:IM-11985-587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) uniprotkb:Q9XU77(uniprot-removed-ac)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6807878|ensemblmetazoa:K09B11.9a.1(transcript)|ensemblmetazoa:WBGene00010713(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001040973.1|wormbase:K09B11.9a|interpro:IPR041209|reactome:R-CEL-204005 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:zWbAI5mawzzlFIZP4rcR6seLYn86239 intact-crc:076030A48BCEB2BF|rigid:/4XTBV93/VHy2sIOicpIejaKop8 false - sufficient binding region:134-941("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EGG0 uniprotkb:Q9GT24 intact:EBI-311986|ensemblmetazoa:K09B11.9a.1 intact:EBI-323555|uniprotkb:O01903|ensemblmetazoa:F59E12.2.1|ensemblmetazoa:F59E12.2.2 psi-mi:g5egg0_caeel(display_long)|uniprotkb:uso-1(gene name)|psi-mi:uso-1(display_short)|uniprotkb:K09B11.9(orf name)|uniprotkb:CELE_K09B11.9(orf name) psi-mi:zyg1_caeel(display_long)|uniprotkb:zyg-1(gene name)|psi-mi:zyg-1(display_short)|uniprotkb:F59E12.2(orf name)|uniprotkb:Zygote defective protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461629|imex:IM-11985-588 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9XU77(uniprot-removed-ac)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6807878|ensemblmetazoa:K09B11.9a.1(transcript)|ensemblmetazoa:WBGene00010713(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001040973.1|wormbase:K09B11.9a|interpro:IPR041209|reactome:R-CEL-204005 refseq:NP_495103.1|wormbase:F59E12.2|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0051225"(spindle assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|ensemblmetazoa:F59E12.2.1(transcript)|ensemblmetazoa:F59E12.2.2(transcript)|ensemblmetazoa:WBGene00006988(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0106311"|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1904779"(regulation of protein localization to centrosome)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR040733|interpro:IPR040734|rcsb pdb:4NKB|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-24892N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zWbAI5mawzzlFIZP4rcR6seLYn86239 rogid:bW56U+tOCdP8UXKTudspR9Oi4/Q6239 intact-crc:436373D3408C1E2B|rigid:lysaBdOIsC0GCI8cS5URNk/q34U false sufficient binding region:134-941("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21295 uniprotkb:G5EGG0 intact:EBI-2004307|uniprotkb:Q21296|ensemblmetazoa:K07F5.13a.1 intact:EBI-311986|ensemblmetazoa:K09B11.9a.1 psi-mi:q21295_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:g5egg0_caeel(display_long)|uniprotkb:uso-1(gene name)|psi-mi:uso-1(display_short)|uniprotkb:K09B11.9(orf name)|uniprotkb:CELE_K09B11.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461639|imex:IM-11985-589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501772.1|wormbase:K07F5.13a|interpro:IPR024864|interpro:IPR025712|ensemblmetazoa:K07F5.13a.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) uniprotkb:Q9XU77(uniprot-removed-ac)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6807878|ensemblmetazoa:K09B11.9a.1(transcript)|ensemblmetazoa:WBGene00010713(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001040973.1|wormbase:K09B11.9a|interpro:IPR041209|reactome:R-CEL-204005 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:CgqZPl+7gsTQJxOMbCCLLuEiUh46239 rogid:zWbAI5mawzzlFIZP4rcR6seLYn86239 intact-crc:7A45C761845707B1|rigid:A07ETe9ejCitEK1g667XWYXf3aQ false - sufficient binding region:134-941("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:G5EGG0 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-311986|ensemblmetazoa:K09B11.9a.1 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:g5egg0_caeel(display_long)|uniprotkb:uso-1(gene name)|psi-mi:uso-1(display_short)|uniprotkb:K09B11.9(orf name)|uniprotkb:CELE_K09B11.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461649|imex:IM-11985-590 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) uniprotkb:Q9XU77(uniprot-removed-ac)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6807878|ensemblmetazoa:K09B11.9a.1(transcript)|ensemblmetazoa:WBGene00010713(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001040973.1|wormbase:K09B11.9a|interpro:IPR041209|reactome:R-CEL-204005 psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:zWbAI5mawzzlFIZP4rcR6seLYn86239 intact-crc:5E7C5E1D98C18573|rigid:iQlmxIrynsqEWfUG51f1/cDUVcs false - sufficient binding region:134-941("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:G5EGG0 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-311986|ensemblmetazoa:K09B11.9a.1 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:g5egg0_caeel(display_long)|uniprotkb:uso-1(gene name)|psi-mi:uso-1(display_short)|uniprotkb:K09B11.9(orf name)|uniprotkb:CELE_K09B11.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461659|imex:IM-11985-591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) uniprotkb:Q9XU77(uniprot-removed-ac)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6807878|ensemblmetazoa:K09B11.9a.1(transcript)|ensemblmetazoa:WBGene00010713(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001040973.1|wormbase:K09B11.9a|interpro:IPR041209|reactome:R-CEL-204005 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:zWbAI5mawzzlFIZP4rcR6seLYn86239 intact-crc:F6A3E71A744A9151|rigid:ThWE0u/E1uJOWdk2c0+3uRfUt04 false - sufficient binding region:134-941("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EGG0 uniprotkb:Q95XY1 intact:EBI-311986|ensemblmetazoa:K09B11.9a.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:g5egg0_caeel(display_long)|uniprotkb:uso-1(gene name)|psi-mi:uso-1(display_short)|uniprotkb:K09B11.9(orf name)|uniprotkb:CELE_K09B11.9(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461669|imex:IM-11985-592 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9XU77(uniprot-removed-ac)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6807878|ensemblmetazoa:K09B11.9a.1(transcript)|ensemblmetazoa:WBGene00010713(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001040973.1|wormbase:K09B11.9a|interpro:IPR041209|reactome:R-CEL-204005 refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zWbAI5mawzzlFIZP4rcR6seLYn86239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:71AB5D3DE8E996D6|rigid:IYMV7i6rXrby6pGUmLu64RpcaEM false sufficient binding region:134-941("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EGG0 uniprotkb:Q65XX1 intact:EBI-311986|ensemblmetazoa:K09B11.9a.1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:g5egg0_caeel(display_long)|uniprotkb:uso-1(gene name)|psi-mi:uso-1(display_short)|uniprotkb:K09B11.9(orf name)|uniprotkb:CELE_K09B11.9(orf name) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461679|imex:IM-11985-593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9XU77(uniprot-removed-ac)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR011989(Armadillo-like helical)|reactome:R-CEL-6807878|ensemblmetazoa:K09B11.9a.1(transcript)|ensemblmetazoa:WBGene00010713(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0045056"(transcytosis)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0061025"(membrane fusion)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001040973.1|wormbase:K09B11.9a|interpro:IPR041209|reactome:R-CEL-204005 refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zWbAI5mawzzlFIZP4rcR6seLYn86239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:DDE2BA2560379802|rigid:lng17I3HSiRGL4Injy3fDKwH9OM false sufficient binding region:134-941("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:P18948 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-320735|uniprotkb:O45176|uniprotkb:Q7KPP7|uniprotkb:Q7YXH2|ensemblmetazoa:K07H8.6c.1 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:vit6_caeel(display_long)|uniprotkb:vit-6(gene name)|psi-mi:vit-6(display_short)|uniprotkb:K07H8.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461689|imex:IM-11985-594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) refseq:NP_001023274.1|refseq:NP_001023275.1|refseq:NP_001023276.1|wormbase:K07H8.6a|wormbase:K07H8.6b|wormbase:K07H8.6c|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR001846(von Willebrand factor, type D)|ensemblmetazoa:K07H8.6c.1(transcript)|ensemblmetazoa:WBGene00006930(gene)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0045735"(nutrient reservoir activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1904807"(negative regulation of protein oxidation) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:Rriiqcl0XiZg+M/MRxOmBfaDmWs6239 intact-crc:78206E73DEC96858|rigid:GydEdgrArircFO7i+Mh0135wjd0 false - sufficient binding region:1346-1651("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61820 uniprotkb:P30642 intact:EBI-2004513|ensemblmetazoa:B0511.10.1 intact:EBI-311981|ensemblmetazoa:R08D7.3.1 psi-mi:eif3e_caeel(display_long)|uniprotkb:eif-3.E(gene name)|psi-mi:eif-3.E(display_short)|uniprotkb:B0511.10(orf name)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym) psi-mi:eif3d_caeel(display_long)|uniprotkb:R08D7.3(orf name)|uniprotkb:eif-3.D(gene name)|psi-mi:eif-3.D(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461699|imex:IM-11985-595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492785.1|wormbase:B0511.10|interpro:IPR019010|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|reactome:R-CEL-72649|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|interpro:IPR036390|ensemblmetazoa:B0511.10.1(transcript)|ensemblmetazoa:WBGene00001228(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e) reactome:R-CEL-72649|ensemblmetazoa:R08D7.3.1(transcript)|ensemblmetazoa:WBGene00001227(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|refseq:NP_498984.1|wormbase:R08D7.3|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|dip:DIP-25819N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:V3tutqInCVPH/ULVmZoeAIqyJ0k6239 rogid:CvW4IPXX62lvTWXOvGSZttuD3cs6239 intact-crc:07974980052FA9B3|rigid:7emeh41Q6bwyJqG45O/qym+dmNQ false sufficient binding region:1-346("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RT11 uniprotkb:G5EG38 intact:EBI-6458195|ensemblmetazoa:B0511.9c.1|uniprotkb:A9D8E6|uniprotkb:G4RT06|uniprotkb:H2KYB5 intact:EBI-311807|ensemblmetazoa:F10B5.6.1 psi-mi:cdc26_caeel(display_long)|uniprotkb:Cell division cycle protein 26 homolog(gene name synonym)|uniprotkb:mat-4(gene name synonym)|uniprotkb:tag-265(gene name synonym)|uniprotkb:B0511.9(orf name)|uniprotkb:cdc-26(gene name)|psi-mi:cdc-26(display_short) psi-mi:cdc16_caeel(display_long)|uniprotkb:emb-27(gene name)|psi-mi:emb-27(display_short)|uniprotkb:Abnormal embryogenesis protein 27(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:apc-6(gene name synonym)|uniprotkb:pod-6(gene name synonym)|uniprotkb:F10B5.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461709|imex:IM-11985-596 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:B0511.9c.1(transcript)|ensemblmetazoa:WBGene00015235(gene)|go:"GO:0005634"(nucleus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:B0511.9a|wormbase:B0511.9b|wormbase:B0511.9d|refseq:NP_001251445.1|refseq:NP_740913.3|refseq:NP_740914.2|refseq:NP_001251447.1|wormbase:B0511.9c|dip:DIP-26086N uniprotkb:Q09536(uniprot-removed-ac)|ensemblmetazoa:F10B5.6.1(transcript)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|ensemblmetazoa:WBGene00001281(gene)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030703"(eggshell formation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:NP_495712.1|wormbase:F10B5.6|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:4EiUm/eby0CTOnoyalmBYdJZmOE6239 rogid:m3yOdVjLNJWITbYs0dThwJzPRf86239 intact-crc:66948A9F9577C847|rigid:ivCnfVM6NCgb+JSxo63DSKR2rAg false sufficient binding region:1-34("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:H2L0F9 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-6461719|ensemblmetazoa:W02F12.4a.1 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:h2l0f9_caeel(display_long)|uniprotkb:W02F12.4(orf name)|uniprotkb:CELE_W02F12.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461723|imex:IM-11985-597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 ensemblmetazoa:W02F12.4a.1(transcript)|ensemblmetazoa:WBGene00020949(gene)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0005737"(cytoplasm)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|refseq:NP_001024182.2|wormbase:W02F12.4a psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:ShTCXF47YLFvGXMA977dxQe4lWI6239 intact-crc:5D9DE664B36ADC6B|rigid:+OrD/9q2y941zcowL44J966yd9U false - sufficient binding region:13-365("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34286 uniprotkb:Q9N5W1 intact:EBI-313778|uniprotkb:Q9BMU3|ensemblmetazoa:C02F5.9.1 intact:EBI-360399 psi-mi:psb1_caeel(display_long)|uniprotkb:pbs-6(gene name)|psi-mi:pbs-6(display_short)|uniprotkb:C02F5.9(orf name)|uniprotkb:Proteasome subunit beta 6(gene name synonym) psi-mi:q9n5w1_caeel(display_long)|uniprotkb:C51G7.4(gene name)|psi-mi:C51G7.4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461733|imex:IM-11985-598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_498806.1|wormbase:C02F5.9|reactome:R-CEL-5632684|ensemblmetazoa:C02F5.9.1(transcript)|ensemblmetazoa:WBGene00003952(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|dip:DIP-24619N|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g54+kg5aHsaQMTBH6xZ9h0/20XQ6239 rogid:/Z/hZ0BAAbzdE9XTRSn+ojXmOIk6239 intact-crc:87AF00CAD8F0E3C3|rigid:5DEQCcPTxUChJlQimlbcixDrhyY false - sufficient binding region:133-579("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34556 uniprotkb:Q17868 intact:EBI-327309|ensemblmetazoa:T05G5.3.1|ensemblmetazoa:T05G5.3.2 intact:EBI-314859|ensemblmetazoa:C09G4.3.1 psi-mi:cdk1_caeel(display_long)|uniprotkb:T05G5.3(orf name)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:cdk-1(gene name)|psi-mi:cdk-1(display_short)|uniprotkb:ncc-1(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:cks1_caeel(display_long)|uniprotkb:cks-1(gene name)|psi-mi:cks-1(display_short)|uniprotkb:dom-6(gene name synonym)|uniprotkb:C09G4.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461743|imex:IM-11985-599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022747.1|wormbase:T05G5.3|reactome:R-CEL-5687128|reactome:R-CEL-110056|reactome:R-CEL-69273|reactome:R-CEL-176408|reactome:R-CEL-2500257|reactome:R-CEL-6804114|reactome:R-CEL-69478|ensemblmetazoa:T05G5.3.1(transcript)|ensemblmetazoa:T05G5.3.2(transcript)|ensemblmetazoa:WBGene00000405(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26477N|reactome:R-CEL-2299718|reactome:R-CEL-2565942|reactome:R-CEL-4419969|reactome:R-CEL-8878166 refseq:NP_501457.1|wormbase:C09G4.3|ensemblmetazoa:C09G4.3.1(transcript)|ensemblmetazoa:WBGene00001051(gene)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR000789(Cyclin-dependent kinase, regulatory subunit)|interpro:IPR036858|dip:DIP-25964N|reactome:R-CEL-69231|reactome:R-CEL-187577 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:J7vmR2h39IuGCiugKb0MzSTbBlg6239 rogid:OlpJM8zMwCqm6eB6A34tlx7WkrI6239 intact-crc:D9BC53031C18615A|rigid:wq6h7cAa4tCaU64EjI2PSVg5FxE false sufficient binding region:13-332("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10653 uniprotkb:P34556 intact:EBI-330851|ensemblmetazoa:ZC168.4.1|ensemblmetazoa:ZC168.4.2|ensemblmetazoa:ZC168.4.3|ensemblmetazoa:ZC168.4.4 intact:EBI-327309|ensemblmetazoa:T05G5.3.1|ensemblmetazoa:T05G5.3.2 psi-mi:ccnb1_caeel(display_long)|uniprotkb:cyb-1(gene name)|psi-mi:cyb-1(display_short)|uniprotkb:ZC168.4(orf name) psi-mi:cdk1_caeel(display_long)|uniprotkb:T05G5.3(orf name)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:cdk-1(gene name)|psi-mi:cdk-1(display_short)|uniprotkb:ncc-1(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461753|imex:IM-11985-600 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-2500257|reactome:R-CEL-176408|refseq:NP_501987.1|wormbase:ZC168.4|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR039361|interpro:IPR036915|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|ensemblmetazoa:WBGene00000865(gene)|ensemblmetazoa:ZC168.4.1(transcript)|ensemblmetazoa:ZC168.4.2(transcript)|ensemblmetazoa:ZC168.4.3(transcript)|ensemblmetazoa:ZC168.4.4(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-CEL-2299718|reactome:R-CEL-2565942|reactome:R-CEL-4419969|reactome:R-CEL-8878166|reactome:R-CEL-6804114|reactome:R-CEL-69273|reactome:R-CEL-69478 refseq:NP_001022747.1|wormbase:T05G5.3|reactome:R-CEL-5687128|reactome:R-CEL-110056|reactome:R-CEL-69273|reactome:R-CEL-176408|reactome:R-CEL-2500257|reactome:R-CEL-6804114|reactome:R-CEL-69478|ensemblmetazoa:T05G5.3.1(transcript)|ensemblmetazoa:T05G5.3.2(transcript)|ensemblmetazoa:WBGene00000405(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26477N|reactome:R-CEL-2299718|reactome:R-CEL-2565942|reactome:R-CEL-4419969|reactome:R-CEL-8878166 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:DQ3G+FwkBrd8WAXo+plVtHz1fDY6239 rogid:J7vmR2h39IuGCiugKb0MzSTbBlg6239 intact-crc:417E944E6F4EAE48|rigid:2e3+SHrr9px9cdKQNrSr8WRG7uc false - sufficient binding region:13-332("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECY0 uniprotkb:P34537 intact:EBI-312458|ensemblmetazoa:C25F6.2a.1|uniprotkb:Q7Z124 intact:EBI-316712|uniprotkb:Q65ZS6|ensemblmetazoa:R05D3.4b.1 psi-mi:dlg1_caeel(display_long)|uniprotkb:dlg-1(gene name)|psi-mi:dlg-1(display_short)|uniprotkb:MAGUK protein DLG-1(gene name synonym)|uniprotkb:SAP97-like protein DLG-1(gene name synonym)|uniprotkb:C25F6.2(orf name)|uniprotkb:CELE_C25F6.2(orf name) psi-mi:bre1_caeel(display_long)|uniprotkb:RING-type E3 ubiquitin transferase bre-1(gene name synonym)|uniprotkb:rfp-1(gene name)|psi-mi:rfp-1(display_short)|uniprotkb:RING finger protein rfp-1(gene name synonym)|uniprotkb:R05D3.4(orf name)|uniprotkb:bre-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461763|imex:IM-11985-601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18165(uniprot-removed-ac)|reactome:R-CEL-451308|reactome:R-CEL-8849932|ensemblmetazoa:C25F6.2a.1(transcript)|ensemblmetazoa:WBGene00001006(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0043113"(receptor clustering)|go:"GO:0043296"(apical junction complex)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR020590|refseq:NP_001024431.1|reactome:R-CEL-438066|refseq:NP_001024432.1|wormbase:C25F6.2a|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|reactome:R-CEL-6794361|wormbase:C25F6.2b refseq:NP_001022699.1|refseq:NP_001022700.1|wormbase:R05D3.4a|wormbase:R05D3.4b|ensemblmetazoa:R05D3.4b.1(transcript)|ensemblmetazoa:WBGene00007008(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006664"(glycolipid metabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|dip:DIP-24823N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vCwmZiXyMpGxNUB88AMyvKDsJfE6239 rogid:s/wdruXbSj8Ah8bVOiyXM+hDw/k6239 intact-crc:F531E6C65C328430|rigid:ZvNPZY+e6wCsFQY2Tuv4AKn6idA false - sufficient binding region:132-837("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34647-1 uniprotkb:P18948 intact:EBI-6455889|ensemblmetazoa:ZK632.1a.1 intact:EBI-320735|uniprotkb:O45176|uniprotkb:Q7KPP7|uniprotkb:Q7YXH2|ensemblmetazoa:K07H8.6c.1 psi-mi:p34647-1(display_long)|uniprotkb:ZK632.1(orf name)|uniprotkb:mcm-6(gene name)|psi-mi:mcm-6(display_short) psi-mi:vit6_caeel(display_long)|uniprotkb:vit-6(gene name)|psi-mi:vit-6(display_short)|uniprotkb:K07H8.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461773|imex:IM-11985-602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2006759(isoform-parent)|ensemblmetazoa:WBGene00003158(gene)|ensemblmetazoa:ZK632.1a.1(transcript) refseq:NP_001023274.1|refseq:NP_001023275.1|refseq:NP_001023276.1|wormbase:K07H8.6a|wormbase:K07H8.6b|wormbase:K07H8.6c|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR001846(von Willebrand factor, type D)|ensemblmetazoa:K07H8.6c.1(transcript)|ensemblmetazoa:WBGene00006930(gene)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0045735"(nutrient reservoir activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1904807"(negative regulation of protein oxidation) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Bv0Zazm8QYFQ5nW05WKMSnLzHVs6239 rogid:Rriiqcl0XiZg+M/MRxOmBfaDmWs6239 intact-crc:7B0FA9180EF4E1AA|rigid:gJ7avf7VxQxYopoHyZQihUJLrx0 false - sufficient binding region:1327-1651("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76371 uniprotkb:O17071 intact:EBI-317201|ensemblmetazoa:F56H1.4.1 intact:EBI-320304|uniprotkb:Q5F4U7|ensemblmetazoa:F23F1.8a.1 psi-mi:prs6a_caeel(display_long)|uniprotkb:rpt-5(gene name)|psi-mi:rpt-5(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 5(gene name synonym)|uniprotkb:F56H1.4(orf name) psi-mi:prs10_caeel(display_long)|uniprotkb:F23F1.8(orf name)|uniprotkb:rpt-4(gene name)|psi-mi:rpt-4(display_short)|uniprotkb:Proteasome regulatory particle ATPase-like protein 4(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit rpt-4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461783|imex:IM-11985-603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|reactome:R-CEL-187577|reactome:R-CEL-5687128|refseq:NP_491672.1|wormbase:F56H1.4|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F56H1.4.1(transcript)|ensemblmetazoa:WBGene00004505(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|reactome:R-CEL-5632684|reactome:R-CEL-6798695|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|interpro:IPR035254 refseq:NP_001022113.1|refseq:NP_001022114.1|wormbase:F23F1.8a|wormbase:F23F1.8b|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|ensemblmetazoa:F23F1.8a.1(transcript)|ensemblmetazoa:WBGene00004504(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR027417|interpro:IPR035263|reactome:R-CEL-8932339|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR032501|interpro:IPR041569|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:JW4UPtYlusTCwjDWZOAyH30g+Sw6239 rogid:gn/Ijzogjc+tbW8p18gnapASCTE6239 intact-crc:7773D3976F206039|rigid:qPrgZCPwA9r+67qFvKwR+XdC2pQ false - sufficient binding region:13-159("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19336 intact:EBI-6460247 intact:EBI-367795|ensemblmetazoa:F11A10.3a.1|ensemblmetazoa:F11A10.3a.2 intact:EBI-6306345 psi-mi:q19336_caeel(display_long)|uniprotkb:mig-32(gene name)|psi-mi:mig-32(display_short)|uniprotkb:CELE_F11A10.3(orf name)|uniprotkb:F11A10.3(orf name) psi-mi:ebi6306345(display_short)|psi-mi:EBI-6460247(display_long)|intact:C17E4.2(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461793|imex:IM-11985-604 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|wormbase:F11A10.3a|refseq:NP_001255620.1|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0046662"(regulation of oviposition)|go:"GO:0046872"(metal ion binding)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:F11A10.3a.1(transcript)|ensemblmetazoa:F11A10.3a.2(transcript)|ensemblmetazoa:WBGene00008684(gene)|go:"GO:0000003"(reproduction)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination) - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:N7ySg+twiLKKe4TZIVvdSUavh2o6239 - intact-crc:10A17D0DFAA14D90 false - sufficient binding region:131-444("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34574 uniprotkb:P34574 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461803|imex:IM-11985-605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 intact-crc:23D0EF5D21B7284A|rigid:XGco9ORxI+pGOgkJURy8j7rgHKI false - sufficient binding region:1310-1681("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18282 uniprotkb:Q9N2L7 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 intact:EBI-2002517|ensemblmetazoa:Y71F9B.7.1 psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:plk2_caeel(display_long)|uniprotkb:plk-2(gene name)|psi-mi:plk-2(display_short)|uniprotkb:Polo-like kinase 2(gene name synonym)|uniprotkb:Y71F9B.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461823|imex:IM-11985-607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) refseq:NP_491036.1|wormbase:Y71F9B.7|interpro:IPR011009(Protein kinase-like)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR033695|interpro:IPR033701|mint:Q9N2L7|interpro:IPR036947|ensemblmetazoa:WBGene00004043(gene)|ensemblmetazoa:Y71F9B.7.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060631"(regulation of meiosis I)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-CEL-156711|reactome:R-CEL-162658|reactome:R-CEL-2299718|reactome:R-CEL-2500257|reactome:R-CEL-2565942|reactome:R-CEL-68884|reactome:R-CEL-69273|reactome:R-CEL-9648025 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 rogid:cyK3fU39dpQAH6oFcSvxe+AU9Mo6239 intact-crc:69B458A7DF1CC6E0|rigid:8DIfD4z1l65WBEG/0Cb1Nc9ty0w false - sufficient binding region:1-285("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18282 uniprotkb:Q18282 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461813|imex:IM-11985-606 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 intact-crc:051E31081A71298A|rigid:9lKowCiRiFiA3knpKGsImFr3Nss false - sufficient binding region:129-193("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:H2KYV3 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-313681|ensemblmetazoa:C18B2.5b.1 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:h2kyv3_caeel(display_long)|uniprotkb:C18B2.5(orf name)|uniprotkb:CELE_C18B2.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461843|imex:IM-11985-609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 uniprotkb:Q8MQD2(uniprot-removed-ac)|refseq:NP_741751.1|interpro:IPR027417|wormbase:C18B2.5b|ensemblmetazoa:C18B2.5b.1(transcript)|ensemblmetazoa:WBGene00015956(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:XM2jTadTzn4fSQ0iOkbTcgKHG5s6239 intact-crc:D6534062BD2259D1|rigid:2eQvpidUqU7sg5EL5fEp798cdA0 false - sufficient binding region:127-699("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34647-1 uniprotkb:Q19965 intact:EBI-6455889|ensemblmetazoa:ZK632.1a.1 intact:EBI-326112|ensemblmetazoa:F32D8.4.1 psi-mi:p34647-1(display_long)|uniprotkb:ZK632.1(orf name)|uniprotkb:mcm-6(gene name)|psi-mi:mcm-6(display_short) psi-mi:q19965_caeel(display_long)|uniprotkb:F32D8.4(orf name)|uniprotkb:CELE_F32D8.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461833|imex:IM-11985-608 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2006759(isoform-parent)|ensemblmetazoa:WBGene00003158(gene)|ensemblmetazoa:ZK632.1a.1(transcript) refseq:NP_505775.3|wormbase:F32D8.4|ensemblmetazoa:F32D8.4.1(transcript)|ensemblmetazoa:WBGene00009329(gene)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0097255"(R2TP complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012981(Nop17p)|dip:DIP-26026N psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Bv0Zazm8QYFQ5nW05WKMSnLzHVs6239 rogid:CxWBq+X2iMjYLFpo6tVUK474ec06239 intact-crc:6B9B9C0D92D766AF|rigid:W4TEnwOZDwsw23QWqxfVOOQ21Bk false - sufficient binding region:128-291("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20168 uniprotkb:Q9N4H7 intact:EBI-895887|ensemblmetazoa:F38E11.5.1 intact:EBI-322591|ensemblmetazoa:Y71F9AL.17.1|ensemblmetazoa:Y71F9AL.17.2 psi-mi:copb2_caeel(display_long)|uniprotkb:copb-2(gene name)|psi-mi:copb-2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:F38E11.5(orf name) psi-mi:q9n4h7_caeel(display_long)|uniprotkb:copa-1(gene name)|psi-mi:copa-1(display_short)|uniprotkb:CELE_Y71F9AL.17(orf name)|uniprotkb:Y71F9AL.17(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461853|imex:IM-11985-610 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501671.1|wormbase:F38E11.5|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR020472|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|reactome:R-CEL-6807878|reactome:R-CEL-6811434|ensemblmetazoa:F38E11.5.1(transcript)|ensemblmetazoa:WBGene00009542(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0048599"(oocyte development) refseq:NP_491069.1|wormbase:Y71F9AL.17|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|ensemblmetazoa:WBGene00022119(gene)|ensemblmetazoa:Y71F9AL.17.1(transcript)|ensemblmetazoa:Y71F9AL.17.2(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|dip:DIP-24621N|reactome:R-CEL-6807878|reactome:R-CEL-6811434 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:3SJ6S3Htfpx07drbV+B3WtohNNs6239 rogid:zhfcqDnbXjalm4vbnKQLHMNEgQI6239 intact-crc:DDA53762732D03F8|rigid:ZN3YiDqETREp++NhdTP2k0aXtpQ false - sufficient binding region:1-276("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:Q9N4H7 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-322591|ensemblmetazoa:Y71F9AL.17.1|ensemblmetazoa:Y71F9AL.17.2 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:q9n4h7_caeel(display_long)|uniprotkb:copa-1(gene name)|psi-mi:copa-1(display_short)|uniprotkb:CELE_Y71F9AL.17(orf name)|uniprotkb:Y71F9AL.17(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461863|imex:IM-11985-611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N refseq:NP_491069.1|wormbase:Y71F9AL.17|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|ensemblmetazoa:WBGene00022119(gene)|ensemblmetazoa:Y71F9AL.17.1(transcript)|ensemblmetazoa:Y71F9AL.17.2(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|dip:DIP-24621N|reactome:R-CEL-6807878|reactome:R-CEL-6811434 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:zhfcqDnbXjalm4vbnKQLHMNEgQI6239 intact-crc:BCD4D6AE6B69D942|rigid:E8G1q46wudONf7kF2DIkC/K7lN0 false - sufficient binding region:1-276("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BKT9 uniprotkb:Q09601 intact:EBI-2005827|ensemblmetazoa:Y37E3.15a.1 intact:EBI-2004755|uniprotkb:O62340|ensemblmetazoa:R06F6.5b.1 psi-mi:q9bkt9_caeel(display_long)|uniprotkb:npp-13(gene name)|psi-mi:npp-13(display_short)|uniprotkb:CELE_Y37E3.15(orf name)|uniprotkb:Y37E3.15(orf name) psi-mi:nup35_caeel(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461873|imex:IM-11985-612 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007231(Nucleoporin interacting component)|refseq:NP_740802.1|wormbase:Y37E3.15a|ensemblmetazoa:WBGene00003799(gene)|ensemblmetazoa:Y37E3.15a.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1903379"(regulation of mitotic chromosome condensation)|go:"GO:1990893"(mitotic chromosome centromere condensation) interpro:IPR017389(Nucleoporin, NUP53)|refseq:NP_496324.1|refseq:NP_496325.1|wormbase:R06F6.5a|wormbase:R06F6.5b|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KQxxaQPFCk9tycEeORD/MJg0krY6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:668BF390C1C319E1|rigid:7MMNbpGZ6Ty6MmGFRKsH9tAHOKc false - sufficient binding region:127-182("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86G90 uniprotkb:Q9XWK3 intact:EBI-313076|ensemblmetazoa:F59A2.1b.1|ensemblmetazoa:F59A2.1b.2|ensemblmetazoa:F59A2.1b.3 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 psi-mi:q86g90_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:F59A2.1(orf name)|uniprotkb:CELE_F59A2.1(orf name) psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461883|imex:IM-11985-613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_871701.1|wormbase:F59A2.1b|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|ensemblmetazoa:F59A2.1b.1(transcript)|ensemblmetazoa:F59A2.1b.2(transcript)|ensemblmetazoa:F59A2.1b.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Y88l3qNpgk4xZvcOCx6msJeOHbo6239 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 intact-crc:33D8DD7BEE2F28AA|rigid:sn49gyFMsS+lYbgeobqWcig9TNM false sufficient binding region:1-269("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7YTG9 uniprotkb:Q95XY1 intact:EBI-2003102|ensemblmetazoa:F11A10.8.1|ensemblmetazoa:F11A10.8.2 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:q7ytg9_caeel(display_long)|uniprotkb:cpsf-4(gene name)|psi-mi:cpsf-4(display_short)|uniprotkb:CELE_F11A10.8(orf name)|uniprotkb:F11A10.8(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461893|imex:IM-11985-614 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023126.1|wormbase:F11A10.8|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|interpro:IPR036855|interpro:IPR036875|reactome:R-CEL-73856|ensemblmetazoa:F11A10.8.1(transcript)|ensemblmetazoa:F11A10.8.2(transcript)|ensemblmetazoa:WBGene00044329(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hFzrsuwJxyQatMLkejzDei/oxYw6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:6FD18C145B78DAC0|rigid:bHq6oGYfqBjXd6sb/OkACdFQPC0 false sufficient binding region:1-265("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:G5EEM5 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-320102|ensemblmetazoa:F22B5.7.1 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:zyg9_caeel(display_long)|uniprotkb:zyg-9(gene name)|psi-mi:zyg-9(display_short)|uniprotkb:F22B5.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461903|imex:IM-11985-615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:NP_495784.1|uniprotkb:O61442(uniprot-removed-ac)|rcsb pdb:2OF3|wormbase:F22B5.7|ensemblmetazoa:WBGene00006994(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051231"(spindle elongation)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0072687"(meiotic spindle)|ensemblmetazoa:F22B5.7.1(transcript)|interpro:IPR034085|interpro:IPR029632 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:d5IkZ+B1AcKT1ZE2uWfbBzd9p5U6239 intact-crc:D914176BD9156448|rigid:28ieiq7Jj08fkyvtOwLkNoVhfaE false - sufficient binding region:1259-1415("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91457 uniprotkb:P34574 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461923|imex:IM-11985-617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 intact-crc:25FDF9CBF3081439|rigid:XGMzXH9x3hosbqaGPTtaJ6dHFWE false - sufficient binding region:1258-1681("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34509 uniprotkb:P34574 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461913|imex:IM-11985-616 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 intact-crc:318ECB2428F66541|rigid:83+78IFPWwfvlibTDbr3pL7VOuI false - sufficient binding region:1258-1681("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09496 uniprotkb:Q9N4E9 intact:EBI-2002622|ensemblmetazoa:C34C12.3.1 intact:EBI-331766|ensemblmetazoa:Y71H2B.3.1 psi-mi:ppp6_caeel(display_long)|uniprotkb:pph-6(gene name)|psi-mi:pph-6(display_short)|uniprotkb:Protein phosphatase pph-6(gene name synonym)|uniprotkb:C34C12.3(orf name) psi-mi:pp4rs_caeel(display_long)|uniprotkb:ppfr-4(gene name)|psi-mi:ppfr-4(display_short)|uniprotkb:Y71H2B.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461933|imex:IM-11985-618 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497714.2|wormbase:C34C12.3|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|ensemblmetazoa:C34C12.3.1(transcript)|ensemblmetazoa:WBGene00007922(gene)|go:"GO:0000235"(astral microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307" refseq:NP_497591.1|wormbase:Y71H2B.3|dip:DIP-27072N|ensemblmetazoa:WBGene00022193(gene)|ensemblmetazoa:Y71H2B.3.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oxbKzyo5Zjub6dw1D4AwrBXv1OM6239 rogid:DmlEnJ9TsnA4eRRlzusNPoTeDy46239 intact-crc:E268B4C62F280631|rigid:XsH8lwBsPmXw9w6EO2JxY53f/tA false - sufficient binding region:1-256("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19584 uniprotkb:Q95QZ9 intact:EBI-319945|ensemblmetazoa:F19B6.2a.1|ensemblmetazoa:F19B6.2a.2 intact:EBI-319957|ensemblmetazoa:F59E12.5b.1|intact:EBI-367827|uniprotkb:O01894 psi-mi:ufd1_caeel(display_long)|uniprotkb:F19B6.2(orf name)|uniprotkb:ufd-1(gene name)|psi-mi:ufd-1(display_short) psi-mi:npl42_caeel(display_long)|uniprotkb:npl-4.2(gene name)|psi-mi:npl-4.2(display_short)|uniprotkb:F59E12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461943|imex:IM-11985-619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502348.1|wormbase:F19B6.2a|ensemblmetazoa:F19B6.2a.1(transcript)|ensemblmetazoa:F19B6.2a.2(transcript)|ensemblmetazoa:WBGene00006733(gene)|go:"GO:0005634"(nucleus)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR004854(Ubiquitin fusion degradation protein UFD1)|interpro:IPR042299|reactome:R-CEL-110320|dip:DIP-26847N refseq:NP_495093.1|wormbase:F59E12.5b|ensemblmetazoa:F59E12.5b.1(transcript)|ensemblmetazoa:WBGene00019121(gene)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR007716(NPL4, zinc-binding putative)|interpro:IPR007717(NPL4)|interpro:IPR016563(Polyubiquitin-tagged protein recognition complex, Npl4 component)|interpro:IPR036443|interpro:IPR037518|reactome:R-CEL-110320|dip:DIP-24492N|wormbase:F59E12.5a|refseq:NP_495094.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:qHXTvaihSryJRpSPlylNXJFCdyI6239 rogid:EGvztDl1e7q4/6drznZF4INOJtw6239 intact-crc:A8824EEC182365BE|rigid:1f/8MiGJ8VOHN7mWPYmx0bgireU false - sufficient binding region:125-529("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95Y13 uniprotkb:Q65XX1 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461953|imex:IM-11985-620 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:CD5F2EBB0DA0229B|rigid:8X4l8WFCBzC2Gb2nlf+31WV+W6U false - sufficient binding region:1-251("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QC4 uniprotkb:Q19207 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 intact:EBI-323336|ensemblmetazoa:F08F8.2.1 psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:q19207_caeel(display_long)|uniprotkb:hmgr-1(gene name)|psi-mi:hmgr-1(display_short)|uniprotkb:F08F8.2(orf name)|uniprotkb:CELE_F08F8.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461963|imex:IM-11985-621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 refseq:NP_498626.2|wormbase:F08F8.2|ensemblmetazoa:F08F8.2.1(transcript)|ensemblmetazoa:WBGene00017268(gene)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|dip:DIP-25409N|reactome:R-CEL-191273 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 rogid:n+mz8S2n9i40K01p7ZmGHnh/Bu86239 intact-crc:12321876DEECD932|rigid:RaKqAQam6JGfrF5+/x6oFztNTPU false - sufficient binding region:1-246("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFV3 uniprotkb:Q9GRZ1 intact:EBI-1187461|intact:EBI-1187509|uniprotkb:G5EDA1|ensemblmetazoa:Y48A6B.11b.1 intact:EBI-313130|ensemblmetazoa:Y59A8B.7.1 psi-mi:rsa2_caeel(display_long)|uniprotkb:Y48A6B.11(orf name)|uniprotkb:rsa-2(gene name)|psi-mi:rsa-2(display_short) psi-mi:q9grz1_caeel(display_long)|uniprotkb:ebp-1(gene name)|psi-mi:ebp-1(display_short)|uniprotkb:Y59A8B.7(orf name)|uniprotkb:CELE_Y59A8B.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461973|imex:IM-11985-622 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7YSJ2(uniprot-removed-ac)|refseq:NP_001022887.1|wormbase:Y48A6B.11b|wormbase:Y48A6B.11a|refseq:NP_001022886.1|ensemblmetazoa:WBGene00012972(gene)|ensemblmetazoa:Y48A6B.11b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0048566"(embryonic digestive tract development) refseq:NP_507526.1|wormbase:Y59A8B.7|ensemblmetazoa:WBGene00013344(gene)|ensemblmetazoa:Y59A8B.7.1(transcript)|go:"GO:0000235"(astral microtubule)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:1904825"(protein localization to microtubule plus-end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR036133|interpro:IPR036872|dip:DIP-25552N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2016/09/27 rogid:7PBwPJFROCL8Mv1INcviVzZGFCE6239 rogid:1bYHNpIf9F0rEpuRtNiUvEu0Zhw6239 intact-crc:856C81AB7260E6D2|rigid:OjCjqZNi/YMdi969YKhxslu9wVo false - sufficient binding region:124-316("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4E9 uniprotkb:Q9XVH6 intact:EBI-331766|ensemblmetazoa:Y71H2B.3.1 intact:EBI-2005572|ensemblmetazoa:W01G7.3.1|ensemblmetazoa:W01G7.3.2 psi-mi:pp4rs_caeel(display_long)|uniprotkb:ppfr-4(gene name)|psi-mi:ppfr-4(display_short)|uniprotkb:Y71H2B.3(orf name) psi-mi:rpb11_caeel(display_long)|uniprotkb:DNA-directed RNA polymerase II subunit J(gene name synonym)|uniprotkb:W01G7.3(orf name)|uniprotkb:rpb-11(gene name)|psi-mi:rpb-11(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461983|imex:IM-11985-623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497591.1|wormbase:Y71H2B.3|dip:DIP-27072N|ensemblmetazoa:WBGene00022193(gene)|ensemblmetazoa:Y71H2B.3.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511 reactome:R-CEL-9018519|refseq:NP_496942.1|wormbase:W01G7.3|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR037685|reactome:R-CEL-113418|reactome:R-CEL-674695|reactome:R-CEL-72086|reactome:R-CEL-72163|reactome:R-CEL-72165|reactome:R-CEL-73776|reactome:R-CEL-73779|reactome:R-CEL-75953|reactome:R-CEL-76042|reactome:R-CEL-77075|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-5578749|reactome:R-CEL-75955|reactome:R-CEL-6796648|reactome:R-CEL-6803529|reactome:R-CEL-6807505|interpro:IPR036603|reactome:R-CEL-112382|ensemblmetazoa:W01G7.3.1(transcript)|ensemblmetazoa:W01G7.3.2(transcript)|ensemblmetazoa:WBGene00012187(gene)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0046983"(protein dimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:DmlEnJ9TsnA4eRRlzusNPoTeDy46239 rogid:PFQWLQzg4Z6p3Qt6OHD15MaZ9B46239 intact-crc:E52B8E91F044229A|rigid:NJh+3uepAsY/aJC2NiHXOqV9rLU false sufficient binding region:1-235("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVP0 uniprotkb:Q9BKP1 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 intact:EBI-312610|ensemblmetazoa:F56B3.2.1 psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:q9bkp1_caeel(display_long)|uniprotkb:F56B3.2(orf name)|uniprotkb:CELE_F56B3.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6461993|imex:IM-11985-624 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) refseq:NP_499983.2|wormbase:F56B3.2|ensemblmetazoa:F56B3.2.1(transcript)|ensemblmetazoa:WBGene00018928(gene)|interpro:IPR006149(Nematode-specific EB region)|dip:DIP-27010N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 rogid:N3bOec5B0I8PhJ+ttgNC3IizzCg6239 intact-crc:0CF643415AD76213|rigid:Cjxgd1xdLvUs9Z2whce2mKqZ4MU false - sufficient binding region:123-432("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4E9 uniprotkb:G5EGK8 intact:EBI-331766|ensemblmetazoa:Y71H2B.3.1 intact:EBI-319655|ensemblmetazoa:F38H4.9.1|ensemblmetazoa:F38H4.9.2|ensemblmetazoa:F38H4.9.3 psi-mi:pp4rs_caeel(display_long)|uniprotkb:ppfr-4(gene name)|psi-mi:ppfr-4(display_short)|uniprotkb:Y71H2B.3(orf name) psi-mi:pp2a_caeel(display_long)|uniprotkb:let-92(gene name)|psi-mi:let-92(display_short)|uniprotkb:F38H4.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462003|imex:IM-11985-625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497591.1|wormbase:Y71H2B.3|dip:DIP-27072N|ensemblmetazoa:WBGene00022193(gene)|ensemblmetazoa:Y71H2B.3.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511 uniprotkb:Q27498(uniprot-removed-ac)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|refseq:NP_502247.1|ensemblmetazoa:F38H4.9.1(transcript)|ensemblmetazoa:F38H4.9.2(transcript)|ensemblmetazoa:F38H4.9.3(transcript)|ensemblmetazoa:WBGene00002363(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0018985"(pronuclear envelope synthesis)|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046872"(metal ion binding)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051299"(centrosome separation)|go:"GO:0106306"|go:"GO:0106307"|wormbase:F38H4.9|reactome:R-CEL-389513|reactome:R-CEL-6811558|interpro:IPR029052|reactome:R-CEL-5673000|reactome:R-CEL-5675221|reactome:R-CEL-69231|reactome:R-CEL-195253|reactome:R-CEL-198753|reactome:R-CEL-202670|reactome:R-CEL-2995383|reactome:R-CEL-69273|reactome:R-CEL-196299|reactome:R-CEL-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:DmlEnJ9TsnA4eRRlzusNPoTeDy46239 rogid:d5e/T74YELePZOaa8rUlLe8oWw86239 intact-crc:B8A4BBAB33600EF7|rigid:OOgGgwYvlH4XPXjfoKz56AV3c1s false sufficient binding region:1-214("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21625 uniprotkb:Q9NAH1 intact:EBI-2004557|ensemblmetazoa:R01H10.1.1 intact:EBI-2004421|ensemblmetazoa:Y47D3A.29a.1 psi-mi:dpoa2_caeel(display_long)|uniprotkb:div-1(gene name)|psi-mi:div-1(display_short)|uniprotkb:Division delayed protein 1(gene name synonym)|uniprotkb:R01H10.1/R01H10.2/Y70G10A.4(orf name) psi-mi:q9nah1_caeel(display_long)|uniprotkb:pola-1(gene name)|psi-mi:pola-1(display_short)|uniprotkb:CELE_Y47D3A.29(orf name)|uniprotkb:Y47D3A.29(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462013|imex:IM-11985-626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499268.1|wormbase:R01H10.1|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016722(DNA polymerase alpha, subunit B)|reactome:R-CEL-68952|reactome:R-CEL-68962|reactome:R-CEL-69091|reactome:R-CEL-69166|reactome:R-CEL-69183|interpro:IPR043034|reactome:R-CEL-113501|ensemblmetazoa:R01H10.1.1(transcript)|ensemblmetazoa:WBGene00001002(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006270"(DNA replication initiation) refseq:NP_001255109.1|wormbase:Y47D3A.29a|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR043502|interpro:IPR038256|interpro:IPR036397|interpro:IPR042087|ensemblmetazoa:WBGene00012936(gene)|ensemblmetazoa:Y47D3A.29a.1(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSX0HtWooJO0Ts8tEehni7+RcnM6239 rogid:pydGCQzhGsrSqJAWdUwfOqll/kY6239 intact-crc:76C43DBD038E92CD|rigid:SQmQvWoPNSdXmqkqM9eePWrLPzs false - sufficient binding region:1210-1428("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6457133 uniprotkb:O44625 intact:EBI-6306363 intact:EBI-2003361|ensemblmetazoa:K11D12.2.1|ensemblmetazoa:K11D12.2.2|ensemblmetazoa:K11D12.2.3|ensemblmetazoa:K11D12.2.4 psi-mi:ebi6306363(display_short)|psi-mi:EBI-6457133(display_long)|intact:F39H11.2x(author assigned name) psi-mi:o44625_caeel(display_long)|uniprotkb:pqn-51(gene name)|psi-mi:pqn-51(display_short)|uniprotkb:CELE_K11D12.2(orf name)|uniprotkb:K11D12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462023|imex:IM-11985-627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_504355.1|interpro:IPR004855(Transcription factor IIA, alpha/beta subunit)|interpro:IPR009088(Transcription factor IIA, beta-barrel)|reactome:R-CEL-9018519|reactome:R-CEL-674695|reactome:R-CEL-6807505|reactome:R-CEL-73776|reactome:R-CEL-73779|reactome:R-CEL-75953|reactome:R-CEL-76042|wormbase:K11D12.2|ensemblmetazoa:K11D12.2.1(transcript)|ensemblmetazoa:K11D12.2.2(transcript)|ensemblmetazoa:K11D12.2.3(transcript)|ensemblmetazoa:K11D12.2.4(transcript)|ensemblmetazoa:WBGene00004136(gene)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter) psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:BGbptk4ARM7I0QBPBIy2XBD0Y1M6239 intact-crc:6BED9F36E29DCA69 false - sufficient binding region:120-354("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34574 uniprotkb:O01422 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 intact:EBI-331413|ensemblmetazoa:B0025.2.1|ensemblmetazoa:B0025.2.2 psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:csn2_caeel(display_long)|uniprotkb:B0025.2(orf name)|uniprotkb:csn-2(gene name)|psi-mi:csn-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462033|imex:IM-11985-628 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N refseq:NP_491740.1|wormbase:B0025.2|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-24665N|ensemblmetazoa:B0025.2.1(transcript)|ensemblmetazoa:B0025.2.2(transcript)|ensemblmetazoa:WBGene00000814(gene)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 rogid:qwX/mKYLxZitZLkfNa3RPYDLYyo6239 intact-crc:8D4804CFCDE990F5|rigid:WnyaCoEpUhb8KshrD0HN6J1nHHs false sufficient binding region:1201-1681("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GT24 uniprotkb:P34574 intact:EBI-323555|uniprotkb:O01903|ensemblmetazoa:F59E12.2.1|ensemblmetazoa:F59E12.2.2 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 psi-mi:zyg1_caeel(display_long)|uniprotkb:zyg-1(gene name)|psi-mi:zyg-1(display_short)|uniprotkb:F59E12.2(orf name)|uniprotkb:Zygote defective protein 1(gene name synonym) psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462053|imex:IM-11985-630 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495103.1|wormbase:F59E12.2|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0051225"(spindle assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|ensemblmetazoa:F59E12.2.1(transcript)|ensemblmetazoa:F59E12.2.2(transcript)|ensemblmetazoa:WBGene00006988(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0106311"|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1904779"(regulation of protein localization to centrosome)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR040733|interpro:IPR040734|rcsb pdb:4NKB|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-24892N refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bW56U+tOCdP8UXKTudspR9Oi4/Q6239 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 intact-crc:8FA17406E27C8EC9|rigid:LQjktRoeJYwOa07APgs022dsaf4 false - sufficient binding region:1201-1681("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:P34574 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462043|imex:IM-11985-629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 intact-crc:865E4AC7FD356F9C|rigid:+MZbOIB1QqUE1vdC1LJKnOJ4C5A false - sufficient binding region:1201-1681("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34574 uniprotkb:Q9U3C1 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 intact:EBI-2004353|ensemblmetazoa:K07F5.13b.1 psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:q9u3c1_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462063|imex:IM-11985-631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N refseq:NP_501771.1|wormbase:K07F5.13b|interpro:IPR024864|interpro:IPR025712|interpro:IPR025574|ensemblmetazoa:K07F5.13b.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 rogid:PBUFj0HXUAAcVEWkwfLNogGoZNQ6239 intact-crc:E847776922D32B79|rigid:vl9IuItGbeH28A/3F/t3vDqTVzk false sufficient binding region:1201-1681("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34574 uniprotkb:Q65XX1 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462083|imex:IM-11985-633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:1120BDF0C2C708E0|rigid:aCTPh6BXVvmptfeYyvNK0Ma1H60 false sufficient binding region:1201-1681("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34574 uniprotkb:Q95XY1 intact:EBI-319001|ensemblmetazoa:T20G5.1.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:clh_caeel(display_long)|uniprotkb:T20G5.1(orf name)|uniprotkb:chc-1(gene name)|psi-mi:chc-1(display_short) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462073|imex:IM-11985-632 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499260.1|wormbase:T20G5.1|ensemblmetazoa:T20G5.1.1(transcript)|ensemblmetazoa:WBGene00011867(gene)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0071439"(clathrin complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-3928665|reactome:R-CEL-432720|reactome:R-CEL-432722|reactome:R-CEL-437239|reactome:R-CEL-5099900|reactome:R-CEL-5140745|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-8866427|reactome:R-CEL-8964038|reactome:R-CEL-9013420|reactome:R-CEL-9013424|mint:P34574|dip:DIP-25251N refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vbsqblpJ1wK5hEo5r2k/9giBsVI6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:BD695AE84A190634|rigid:NkPQU+elSoA/HSmhXU8hZIOdnH8 false sufficient binding region:1201-1681("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19286 uniprotkb:G5EFV3 intact:EBI-320062|uniprotkb:Q21064|uniprotkb:Q95QM2|ensemblmetazoa:F10C1.7a.1 intact:EBI-1187461|intact:EBI-1187509|uniprotkb:G5EDA1|ensemblmetazoa:Y48A6B.11b.1 psi-mi:ifb2_caeel(display_long)|uniprotkb:ifb-2(gene name)|psi-mi:ifb-2(display_short)|uniprotkb:F10C1.7(orf name)|uniprotkb:Intermediate filament protein B2(gene name synonym)|uniprotkb:Cel IF B2(gene name synonym) psi-mi:rsa2_caeel(display_long)|uniprotkb:Y48A6B.11(orf name)|uniprotkb:rsa-2(gene name)|psi-mi:rsa-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462093|imex:IM-11985-634 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495133.1|refseq:NP_495134.1|wormbase:F10C1.7a|wormbase:F10C1.7c|ensemblmetazoa:F10C1.7a.1(transcript)|ensemblmetazoa:WBGene00002054(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0030054"(cell junction)|go:"GO:0045179"(apical cortex)|go:"GO:1990357"(terminal web)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-26763N uniprotkb:Q7YSJ2(uniprot-removed-ac)|refseq:NP_001022887.1|wormbase:Y48A6B.11b|wormbase:Y48A6B.11a|refseq:NP_001022886.1|ensemblmetazoa:WBGene00012972(gene)|ensemblmetazoa:Y48A6B.11b.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0048566"(embryonic digestive tract development) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2016/09/27 rogid:SIkUfQ59iJC29JoQFWYxCZdKiv86239 rogid:7PBwPJFROCL8Mv1INcviVzZGFCE6239 intact-crc:E17280241E28D0D2|rigid:8yMvxXCFzwoaT4eQs0h8CR0JOlg false sufficient binding region:119-543("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q94420 uniprotkb:Q95QY7 intact:EBI-320790|uniprotkb:Q94139|ensemblmetazoa:ZK858.4a.1 intact:EBI-2007707|ensemblmetazoa:C02F5.12.1 psi-mi:mel26_caeel(display_long)|uniprotkb:ZK858.4(orf name)|uniprotkb:mel-26(gene name)|psi-mi:mel-26(display_short) psi-mi:ykka_caeel(display_long)|uniprotkb:C02F5.12(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462103|imex:IM-11985-635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492449.2|wormbase:ZK858.4a|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0000132"(establishment of mitotic spindle orientation)|ensemblmetazoa:WBGene00003209(gene)|ensemblmetazoa:ZK858.4a.1(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031674"(I band)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032888"(regulation of mitotic spindle elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|dip:DIP-27179N|reactome:R-CEL-5632684 refseq:NP_498805.2|wormbase:C02F5.12|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensemblmetazoa:C02F5.12.1(transcript)|ensemblmetazoa:WBGene00015352(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LdD7Fd/bItR1N1LukujfPZi0MqI6239 rogid:BIYVCXL5xUyMknTIypCYpzb1x/I6239 intact-crc:E0DD8C5173960644|rigid:6JpqVvcMUy9nLnwj7zX9084Y/Ok false - sufficient binding region:119-278("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09248 uniprotkb:Q95005 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 intact:EBI-316796|ensemblmetazoa:C36B1.4.1|ensemblmetazoa:C36B1.4.2 psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:psa7_caeel(display_long)|uniprotkb:pas-4(gene name)|psi-mi:pas-4(display_short)|uniprotkb:C36B1.4(orf name)|uniprotkb:Proteasome subunit alpha 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462113|imex:IM-11985-636 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 reactome:R-CEL-5689603|reactome:R-CEL-5689880|refseq:NP_492360.1|wormbase:C36B1.4|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:C36B1.4.1(transcript)|ensemblmetazoa:C36B1.4.2(transcript)|ensemblmetazoa:WBGene00003925(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 rogid:WWXt5jeuKRCX9WomT3Wqk45PRIc6239 intact-crc:BBAAD24914F24ED5|rigid:OjmTjQ+85gtD4lBpf6V1qabLPbo false sufficient binding region:1-192("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:O01900 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462123|imex:IM-11985-637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:6788CA058DDBCF06|rigid:7DtRe5ZuTLAhjv6x5CVo4uD08t8 false - sufficient binding region:1156-1621("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:O01900 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-315098|ensemblmetazoa:F59E12.9.1 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:o01900_caeel(display_long)|uniprotkb:F59E12.9(orf name)|uniprotkb:CELE_F59E12.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462133|imex:IM-11985-638 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) refseq:NP_495100.1|wormbase:F59E12.9|ensemblmetazoa:F59E12.9.1(transcript)|ensemblmetazoa:WBGene00019124(gene)|dip:DIP-24516N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:fmWiN1f2YlH7zOn3hYhznBrLMu86239 intact-crc:CBC12D1D0505C1D2|rigid:e0bbxduvzUUqGa0sa041CY/wNR8 false - sufficient binding region:1156-1621("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20351 uniprotkb:Q19286 intact:EBI-2003656|uniprotkb:Q8T8N1|ensemblmetazoa:F42G9.8.1 intact:EBI-320062|uniprotkb:Q21064|uniprotkb:Q95QM2|ensemblmetazoa:F10C1.7a.1 psi-mi:tpstb_caeel(display_long)|uniprotkb:Tyrosylprotein sulfotransferase(gene name synonym)|uniprotkb:F42G9.8(orf name)|uniprotkb:tpst-2(gene name)|psi-mi:tpst-2(display_short) psi-mi:ifb2_caeel(display_long)|uniprotkb:ifb-2(gene name)|psi-mi:ifb-2(display_short)|uniprotkb:F10C1.7(orf name)|uniprotkb:Intermediate filament protein B2(gene name synonym)|uniprotkb:Cel IF B2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462143|imex:IM-11985-639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497256.1|wormbase:F42G9.8|interpro:IPR026634|interpro:IPR027417|ensemblmetazoa:F42G9.8.1(transcript)|ensemblmetazoa:WBGene00018365(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006478"(peptidyl-tyrosine sulfation)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0008476"(protein-tyrosine sulfotransferase activity) refseq:NP_495133.1|refseq:NP_495134.1|wormbase:F10C1.7a|wormbase:F10C1.7c|ensemblmetazoa:F10C1.7a.1(transcript)|ensemblmetazoa:WBGene00002054(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0030054"(cell junction)|go:"GO:0045179"(apical cortex)|go:"GO:1990357"(terminal web)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR016451(Intermediate filament, Ifb-2)|interpro:IPR036415|interpro:IPR039008|reactome:R-CEL-4419969|dip:DIP-26763N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:S6qylnnMtTn+mWQWGCSzFCCY4/s6239 rogid:SIkUfQ59iJC29JoQFWYxCZdKiv86239 intact-crc:AFC85E4437E8887A|rigid:GT9GoQW8Irv46F6wk3sVgS9jVOk false - sufficient binding region:115-543("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q8MXR2 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-327674|ensemblmetazoa:Y73B6BL.33a.1 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q8mxr2_caeel(display_long)|uniprotkb:hrpf-2(gene name)|psi-mi:hrpf-2(display_short)|uniprotkb:CELE_Y73B6BL.33(orf name)|uniprotkb:Y73B6BL.33(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462153|imex:IM-11985-640 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) refseq:NP_741422.1|wormbase:Y73B6BL.33a|ensemblmetazoa:WBGene00022253(gene)|ensemblmetazoa:Y73B6BL.33a.1(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|dip:DIP-24945N|reactome:R-CEL-72163 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:vstHX9nskJYcL8v9uG44qxSW+8Q6239 intact-crc:99D3338F90F88CDA|rigid:/pBLPWvlWFf4Bi5fasyToIXy/XQ false - sufficient binding region:114-610("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q10923 uniprotkb:G5EFX8 intact:EBI-313231|ensemblmetazoa:B0286.4a.1|ensemblmetazoa:B0286.4a.2 intact:EBI-2006376|ensemblmetazoa:Y56A3A.1a.1 psi-mi:q10923_caeel(display_long)|uniprotkb:ntl-2(gene name)|psi-mi:ntl-2(display_short)|uniprotkb:B0286.4(orf name)|uniprotkb:CELE_B0286.4(orf name) psi-mi:g5efx8_caeel(display_long)|uniprotkb:ntl-3(gene name)|psi-mi:ntl-3(display_short)|uniprotkb:CELE_Y56A3A.1(orf name)|uniprotkb:Y56A3A.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462163|imex:IM-11985-641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494772.1|wormbase:B0286.4a|ensemblmetazoa:B0286.4a.1(transcript)|ensemblmetazoa:B0286.4a.2(transcript)|ensemblmetazoa:WBGene00003825(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|dip:DIP-25406N interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|refseq:NP_001076652.1|uniprotkb:Q9U233(uniprot-removed-ac)|interpro:IPR040168|interpro:IPR038635|wormbase:Y56A3A.1a|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|ensemblmetazoa:WBGene00003826(gene)|ensemblmetazoa:Y56A3A.1a.1(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030015"(CCR4-NOT core complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hTQSp0NYuQ2fFWniZrrziSvpSMQ6239 rogid:W3RWMMcuA/t1m3bzpthiE8jdNrg6239 intact-crc:63108E8DCA132F47|rigid:1Gza+kFE4sxXvNLsgpAB/8Ehvt8 false sufficient binding region:114-444("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95YF3 uniprotkb:O02655 intact:EBI-314525|ensemblmetazoa:C07H6.5.1 intact:EBI-2002110|ensemblmetazoa:F47G4.7.1 psi-mi:cgh1_caeel(display_long)|uniprotkb:C07H6.5(orf name)|uniprotkb:Conserved germline helicase 1(gene name synonym)|uniprotkb:cgh-1(gene name)|psi-mi:cgh-1(display_short) psi-mi:dcam_caeel(display_long)|uniprotkb:smd-1(gene name)|psi-mi:smd-1(display_short)|uniprotkb:samdc(gene name synonym)|uniprotkb:F47G4.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462173|imex:IM-11985-642 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498646.1|wormbase:C07H6.5|ensemblmetazoa:C07H6.5.1(transcript)|ensemblmetazoa:WBGene00000479(gene)|go:"GO:0000932"(P-body)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048477"(oogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:7DTJ|rcsb pdb:7DTK|reactome:R-CEL-430039|dip:DIP-25457N refseq:NP_493448.1|interpro:IPR001985(S-adenosylmethionine decarboxylase)|interpro:IPR016067(S-adenosylmethionine decarboxylase, core)|interpro:IPR018166|reactome:R-CEL-351202|wormbase:F47G4.7|ensemblmetazoa:F47G4.7.1(transcript)|ensemblmetazoa:WBGene00004875(gene)|go:"GO:0004014"(adenosylmethionine decarboxylase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006557"(S-adenosylmethioninamine biosynthetic process)|go:"GO:0006597"(spermine biosynthetic process)|go:"GO:0008295"(spermidine biosynthetic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:G1utRcadsXjIYlYrrKc2yhCjonk6239 rogid:wHKdRz/lDhGqEF5kCuWgdYgD+jk6239 intact-crc:12E0F4AC195A5D09|rigid:s50p/jhX7vS9mhp3125MpN6sgcc false - sufficient binding region:11-368("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:P17139 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-319671|uniprotkb:Q6LAD0|ensemblmetazoa:K04H4.1a.1 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:co4a1_caeel(display_long)|uniprotkb:emb-9(gene name)|psi-mi:emb-9(display_short)|uniprotkb:clb-2(gene name synonym)|uniprotkb:K04H4.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462183|imex:IM-11985-643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|refseq:NP_001022663.1|wormbase:K04H4.1a|wormbase:K04H4.1b|refseq:NP_001022662.2|ensemblmetazoa:K04H4.1a.1(transcript)|ensemblmetazoa:WBGene00001263(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR036954 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:PAygwwh1z4+A+1x0KmF3LiN6qKw6239 intact-crc:60DC92D63D644581|rigid:LelJUcOri6u30pLBaOkrN+f4sWs false - sufficient binding region:1134-1759("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17139 uniprotkb:Q95XY1 intact:EBI-319671|uniprotkb:Q6LAD0|ensemblmetazoa:K04H4.1a.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:co4a1_caeel(display_long)|uniprotkb:emb-9(gene name)|psi-mi:emb-9(display_short)|uniprotkb:clb-2(gene name synonym)|uniprotkb:K04H4.1(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462193|imex:IM-11985-644 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|refseq:NP_001022663.1|wormbase:K04H4.1a|wormbase:K04H4.1b|refseq:NP_001022662.2|ensemblmetazoa:K04H4.1a.1(transcript)|ensemblmetazoa:WBGene00001263(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR036954 refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PAygwwh1z4+A+1x0KmF3LiN6qKw6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:2203D0CD68562064|rigid:cN6P/aqM2M1Gr9MeL0rY2bfCXOQ false sufficient binding region:1134-1759("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21021 uniprotkb:Q9N5U1 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 intact:EBI-2005375|ensemblmetazoa:T22F3.3a.1 psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:q9n5u1_caeel(display_long)|uniprotkb:pygl-1(gene name)|psi-mi:pygl-1(display_short)|uniprotkb:CELE_T22F3.3(orf name)|uniprotkb:T22F3.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462213|imex:IM-11985-646 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_504007.1|wormbase:T22F3.3a|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|reactome:R-CEL-70221|interpro:IPR035090|ensemblmetazoa:T22F3.3a.1(transcript)|ensemblmetazoa:WBGene00020696(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 rogid:hxlfa3e+4GTuwc4kabxrVxbDecs6239 intact-crc:92199230921CC126|rigid:7wUk63zPDaFCXQwpIhfS0r6115o false sufficient binding region:1-133("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21021 uniprotkb:Q21021 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462203|imex:IM-11985-645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 intact-crc:BAF42F498E6431D1|rigid:B+OiUdA+50mAR+txqaO/k8u52pU false sufficient binding region:1-133("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21021 uniprotkb:Q9N4L2 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 intact:EBI-2006816|ensemblmetazoa:ZK993.1a.1 psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:q9n4l2_caeel(display_long)|uniprotkb:ceh-45(gene name)|psi-mi:ceh-45(display_short)|uniprotkb:CELE_ZK993.1(orf name)|uniprotkb:ZK993.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462223|imex:IM-11985-647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_490823.1|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|wormbase:ZK993.1a|ensemblmetazoa:WBGene00022837(gene)|ensemblmetazoa:ZK993.1a.1(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 rogid:7Iey8Vkqv29PamcScQgOnDHC4As6239 intact-crc:254B794480821B88|rigid:7VpVLlnkIiuqOYgvDVJ86vb+/0w false sufficient binding region:1-133("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P90860 uniprotkb:G5ECG0 intact:EBI-2006349|ensemblmetazoa:F36A2.7.1 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:p90860_caeel(display_long)|uniprotkb:F36A2.7(orf name)|uniprotkb:CELE_F36A2.7(orf name) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462233|imex:IM-11985-648 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492383.1|wormbase:F36A2.7|ensemblmetazoa:F36A2.7.1(transcript)|ensemblmetazoa:WBGene00009454(gene)|go:"GO:0016021"(integral component of membrane) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:SwzaXzWCcXrUbUkqlmU0efYRYmU6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:8FE55015EC1B6D32|rigid:ETyPAcpSYRfnOIKOhvQPhNDH238 false sufficient binding region:1-130("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76447 uniprotkb:Q09601-1 intact:EBI-314341|ensemblmetazoa:ZK1055.1.1 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:o76447_caeel(display_long)|uniprotkb:hcp-1(gene name)|psi-mi:hcp-1(display_short)|uniprotkb:CELE_ZK1055.1(orf name)|uniprotkb:ZK1055.1(orf name) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462243|imex:IM-11985-649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504677.1|wormbase:ZK1055.1|mint:O76447|ensemblmetazoa:WBGene00001829(gene)|ensemblmetazoa:ZK1055.1.1(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0008104"(protein localization)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0051316"(attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation)|go:"GO:0051382"(kinetochore assembly)|dip:DIP-24595N intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oUJ4tKfuilFWV5Hc2nmQ/QxGLcM6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:950DC17AD4DD3116|rigid:CMWnLuJCeYTDGWQT/YXSs5ElJKI false sufficient binding region:1119-1475("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09248 uniprotkb:Q5WRT9 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 intact:EBI-2002551|ensemblmetazoa:R07G3.3b.1 psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:q5wrt9_caeel(display_long)|uniprotkb:npp-21(gene name)|psi-mi:npp-21(display_short)|uniprotkb:CELE_R07G3.3(orf name)|uniprotkb:R07G3.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462253|imex:IM-11985-650 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 wormbase:R07G3.3b|refseq:NP_741023.2|ensemblmetazoa:R07G3.3b.1(transcript)|ensemblmetazoa:WBGene00019940(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:1901673"(regulation of mitotic spindle assembly) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2019/07/08 rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 rogid:E11z678RDRiw7coF5Q4DE/H01Z06239 intact-crc:ADB40F0544EFB880|rigid:Jb0n1x3ENi+P5mwbwufGGLBf7F8 false - sufficient binding region:11-265("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02482 uniprotkb:Q93616 intact:EBI-314716|uniprotkb:P91912|ensemblmetazoa:W02D3.9.1|ensemblmetazoa:W02D3.9.2 intact:EBI-2005589|ensemblmetazoa:F27D4.2a.1 psi-mi:unc37_caeel(display_long)|uniprotkb:unc-37(gene name)|psi-mi:unc-37(display_short)|uniprotkb:esg(gene name synonym)|uniprotkb:W02D3.9(orf name)|uniprotkb:Uncoordinated protein 37(gene name synonym) psi-mi:q93616_caeel(display_long)|uniprotkb:CELE_F27D4.2(orf name)|uniprotkb:F27D4.2(orf name)|uniprotkb:lsy-22(gene name)|psi-mi:lsy-22(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462263|imex:IM-11985-651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-4641265|refseq:NP_491932.1|wormbase:W02D3.9|reactome:R-CEL-3769402|ensemblmetazoa:W02D3.9.1(transcript)|ensemblmetazoa:W02D3.9.2(transcript)|ensemblmetazoa:WBGene00006773(gene)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008134"(transcription factor binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|dip:DIP-27333N|reactome:R-CEL-201722 refseq:NP_001122461.1|wormbase:F27D4.2a|ensemblmetazoa:F27D4.2a.1(transcript)|ensemblmetazoa:WBGene00009188(gene)|go:"GO:0140297"(DNA-binding transcription factor binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+e4X3QH+GChhuO2oAhaNGVwnO/o6239 rogid:M3oHVB95AOsgyd4wWVgFcOUcics6239 intact-crc:434A57A00B425A7A|rigid:c0XcxAIm3BhQP/KxHOxzd6iU6Oo false sufficient binding region:1-101("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U3C1 uniprotkb:Q65XX1 intact:EBI-2004353|ensemblmetazoa:K07F5.13b.1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:q9u3c1_caeel(display_long)|uniprotkb:npp-1(gene name)|psi-mi:npp-1(display_short)|uniprotkb:CELE_K07F5.13(orf name)|uniprotkb:K07F5.13(orf name) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462273|imex:IM-11985-652 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501771.1|wormbase:K07F5.13b|interpro:IPR024864|interpro:IPR025712|interpro:IPR025574|ensemblmetazoa:K07F5.13b.1(transcript)|ensemblmetazoa:WBGene00003787(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048477"(oogenesis) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PBUFj0HXUAAcVEWkwfLNogGoZNQ6239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:98215D5BC60882D0|rigid:6/HpD5BwXNaupKuRjfiwzOl/5rg false - sufficient binding region:1-101("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q95XY1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462283|imex:IM-11985-653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:CD0F70DAAEC2AF9D|rigid:DyM046xxJzwZDwswX8FBieWcwLI false sufficient binding region:1-101("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q65XX1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462293|imex:IM-11985-654 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:52C395DAEB330A6D|rigid:+WrhjnJLr0RbAbDw4HBhb9EMr7Y false - sufficient binding region:1-101("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19749 uniprotkb:Q09601-1 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462303|imex:IM-11985-655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:68E91BDB8D85A7E7|rigid:YrWgzzoDfrn0UWfk595biodA7ZU false sufficient binding region:108-507("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4H0 uniprotkb:O62333 intact:EBI-6462316|ensemblmetazoa:M110.5a.1|ensemblmetazoa:M110.5a.2 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 psi-mi:q8i4h0_caeel(display_long)|uniprotkb:M110.5(orf name)|uniprotkb:dab-1(gene name)|psi-mi:dab-1(display_short)|uniprotkb:CELE_M110.5(orf name) psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462313|imex:IM-11985-656 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:M110.5a.1(transcript)|ensemblmetazoa:M110.5a.2(transcript)|ensemblmetazoa:WBGene00000894(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0009306"(protein secretion)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0018991"(oviposition)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040017"(positive regulation of locomotion)|go:"GO:0042395"(ecdysis, collagen and cuticulin-based cuticle)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028761|wormbase:M110.5a|refseq:NP_495731.3|dip:DIP-24731N interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oZnH4wRm8u3BNkSs5iHq1Gcr4uQ6239 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 intact-crc:01CB6AEF40655CEB|rigid:jkICqVQzwXNo1HyDbe3eglhWITs false sufficient binding region:108-490("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL3 uniprotkb:Q21531 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 intact:EBI-2004518|ensemblmetazoa:M110.4a.1 psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:q21531_caeel(display_long)|uniprotkb:ifg-1(gene name)|psi-mi:ifg-1(display_short)|uniprotkb:CELE_M110.4(orf name)|uniprotkb:M110.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462328|imex:IM-11985-657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 refseq:NP_001022259.1|wormbase:M110.4a|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|ensemblmetazoa:M110.4a.1(transcript)|ensemblmetazoa:WBGene00002066(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 rogid:Fk1l4aR/CnNvJUmqwR2eWyoO6NU6239 intact-crc:B9784DAC04FACD90|rigid:9FsFfsi4EnSy/Nse5uAjJR3iQuQ false - sufficient binding region:1071-1156("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21531 uniprotkb:G5ECL3 intact:EBI-2004518|ensemblmetazoa:M110.4a.1 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 psi-mi:q21531_caeel(display_long)|uniprotkb:ifg-1(gene name)|psi-mi:ifg-1(display_short)|uniprotkb:CELE_M110.4(orf name)|uniprotkb:M110.4(orf name) psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462338|imex:IM-11985-658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022259.1|wormbase:M110.4a|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|ensemblmetazoa:M110.4a.1(transcript)|ensemblmetazoa:WBGene00002066(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Fk1l4aR/CnNvJUmqwR2eWyoO6NU6239 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 intact-crc:1DDC51D41F7FAFB1|rigid:9FsFfsi4EnSy/Nse5uAjJR3iQuQ false sufficient binding region:1070-1156("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G2HK02 uniprotkb:P54871 intact:EBI-6462351|ensemblmetazoa:Y57A10A.18d.1 intact:EBI-2007078|uniprotkb:Q22962|ensemblmetazoa:F25B4.6.1 psi-mi:g2hk02_caeel(display_long)|uniprotkb:Y57A10A.18(orf name)|uniprotkb:pqn-87(gene name)|psi-mi:pqn-87(display_short)|uniprotkb:CELE_Y57A10A.18(orf name) psi-mi:hmcs_caeel(display_long)|uniprotkb:hmgs-1(gene name)|psi-mi:hmgs-1(display_short)|uniprotkb:3-hydroxy-3-methylglutaryl coenzyme A synthase(gene name synonym)|uniprotkb:F25B4.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462348|imex:IM-11985-659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00004167(gene)|ensemblmetazoa:Y57A10A.18d.1(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|refseq:NP_001254336.1|wormbase:Y57A10A.18d reactome:R-CEL-191273|reactome:R-CEL-77111|refseq:NP_504496.1|wormbase:F25B4.6|interpro:IPR000590(Hydroxymethylglutaryl-coenzyme A synthase, active site)|interpro:IPR013746(Hydroxymethylglutaryl-coenzyme A synthase C-terminal)|interpro:IPR013528(Hydroxymethylglutaryl-coenzyme A synthase, N-terminal)|interpro:IPR010122(Hydroxymethylglutaryl-CoA synthase, eukaryotic)|interpro:IPR016039(Thiolase-like)|ensemblmetazoa:F25B4.6.1(transcript)|ensemblmetazoa:WBGene00017769(gene)|go:"GO:0004421"(hydroxymethylglutaryl-CoA synthase activity)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0010142"(farnesyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0016126"(sterol biosynthetic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:/uQL7fxi+8tlRQvY7v6RT9CEqtM6239 rogid:BdI5bO3m7yPsO1Vq6zTTt/2Qm2c6239 intact-crc:C5C15EAA53DD470D|rigid:nYVLtvOxgpzCbZzi2TR+uEwfYTY false sufficient binding region:1068-1479("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL3 uniprotkb:Q21954 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 intact:EBI-328468|ensemblmetazoa:R12B2.2.1 psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:q21954_caeel(display_long)|uniprotkb:R12B2.2(orf name)|uniprotkb:CELE_R12B2.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462364|imex:IM-11985-660 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 refseq:NP_498255.2|wormbase:R12B2.2|dip:DIP-27181N|ensemblmetazoa:R12B2.2.1(transcript)|ensemblmetazoa:WBGene00020018(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|interpro:IPR027095|reactome:R-CEL-162658 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 rogid:y40T3hsl6N78Jq4AcI0SqFjw9eI6239 intact-crc:A701CC54719F694E|rigid:I5QtKYECqQ52wd9tXC0c/e/fik8 false - sufficient binding region:105-281("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44175 uniprotkb:P34429 intact:EBI-323379|ensemblmetazoa:F58F6.4.1 intact:EBI-315471|uniprotkb:Q8ST15|ensemblmetazoa:F44B9.8.1 psi-mi:o44175_caeel(display_long)|uniprotkb:rfc-2(gene name)|psi-mi:rfc-2(display_short)|uniprotkb:F58F6.4(orf name)|uniprotkb:CELE_F58F6.4(orf name) psi-mi:rfc5_caeel(display_long)|uniprotkb:F44B9.8(orf name)|uniprotkb:Activator 1 subunit 5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462374|imex:IM-11985-661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500069.1|wormbase:F58F6.4|reactome:R-CEL-110320|reactome:R-CEL-69091|ensemblmetazoa:F58F6.4.1(transcript)|ensemblmetazoa:WBGene00004338(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|reactome:R-CEL-6782135|reactome:R-CEL-6782210|dip:DIP-26649N|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397 refseq:NP_498750.2|wormbase:F44B9.8|reactome:R-CEL-110320|reactome:R-CEL-69091|reactome:R-CEL-110312|reactome:R-CEL-110314|reactome:R-CEL-174411|reactome:R-CEL-176187|reactome:R-CEL-5651801|reactome:R-CEL-5655862|reactome:R-CEL-5656169|reactome:R-CEL-5696397|reactome:R-CEL-6782135|reactome:R-CEL-6782210|ensemblmetazoa:F44B9.8.1(transcript)|ensemblmetazoa:WBGene00018409(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|dip:DIP-27001N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:X/GM1+yTwsAHs0cFQlIvIC4+ohw6239 rogid:RbC1EnOYlqMnvDR/47NfuUSHZVA6239 intact-crc:94F015F6713E237A|rigid:gwgvhsn2ukRbDzjuPJ8ObqhHFEk false sufficient binding region:10-334("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44156 uniprotkb:Q09583 intact:EBI-318264|ensemblmetazoa:CD4.6.1 intact:EBI-315406|ensemblmetazoa:ZK945.2.1|ensemblmetazoa:ZK945.2.2 psi-mi:psa1_caeel(display_long)|uniprotkb:pas-6(gene name)|psi-mi:pas-6(display_short)|uniprotkb:CD4.6(orf name)|uniprotkb:Proteasome subunit alpha 6(gene name synonym) psi-mi:psa3_caeel(display_long)|uniprotkb:pas-7(gene name)|psi-mi:pas-7(display_short)|uniprotkb:ZK945.2(orf name)|uniprotkb:Proteasome subunit alpha 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462384|imex:IM-11985-662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504472.1|wormbase:CD4.6|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:CD4.6.1(transcript)|ensemblmetazoa:WBGene00003927(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR035144|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 refseq:NP_496177.2|wormbase:ZK945.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:WBGene00003928(gene)|ensemblmetazoa:ZK945.2.1(transcript)|ensemblmetazoa:ZK945.2.2(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|interpro:IPR037555|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:D/OFB0z6DBE6ohjjHkvLHgK9jCI6239 rogid:OOdurA40PpJd/0X3BA8Z5ZWqCuM6239 intact-crc:AA363852D0BCA87D|rigid:BC67rxYKEdka+p+NICpehIhMNTo false sufficient binding region:10-260("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6BEV5 uniprotkb:P34334 intact:EBI-2002318|intact:EBI-2923757|intact:EBI-2924015|ensemblmetazoa:R06F6.12.1 intact:EBI-315272|ensemblmetazoa:C14B9.7.1 psi-mi:yrmc_caeel(display_long)|uniprotkb:R06F6.12(orf name) psi-mi:rl21_caeel(display_long)|uniprotkb:rpl-21(gene name)|psi-mi:rpl-21(display_short)|uniprotkb:C14B9.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462394|imex:IM-11985-663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022277.1|wormbase:R06F6.12|ensemblmetazoa:R06F6.12.1(transcript)|ensemblmetazoa:WBGene00023418(gene) refseq:NP_498774.1|wormbase:C14B9.7|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-975957|ensemblmetazoa:C14B9.7.1(transcript)|ensemblmetazoa:WBGene00004433(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR001147(Ribosomal protein L21e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018259|interpro:IPR036948|reactome:R-CEL-975956|dip:DIP-24597N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:jP7TZCce2muoY78Ruk/qCSELK5M6239 rogid:/XZSKC1tlKfo/aqAkQ+etoJ5PWY6239 intact-crc:E7F31A193CCB00C5|rigid:mSYQCJTfDGIQoVTZed11jtpzWCs false sufficient binding region:102-417("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P37165-2 uniprotkb:Q6BEV5 intact:EBI-6462407|ensemblmetazoa:H06I04.4b.1 intact:EBI-2002318|intact:EBI-2923757|intact:EBI-2924015|ensemblmetazoa:R06F6.12.1 psi-mi:p37165-2(display_long)|uniprotkb:H06I04.4(orf name)|uniprotkb:ubl-1(gene name)|psi-mi:ubl-1(display_short) psi-mi:yrmc_caeel(display_long)|uniprotkb:R06F6.12(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462404|imex:IM-11985-664 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:H06I04.4b.1(transcript)|ensemblmetazoa:WBGene00006725(gene)|intact:EBI-323634(isoform-parent) refseq:NP_001022277.1|wormbase:R06F6.12|ensemblmetazoa:R06F6.12.1(transcript)|ensemblmetazoa:WBGene00023418(gene) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:d6fEjL2oISSd7tGbuMymPZ4onrI6239 rogid:jP7TZCce2muoY78Ruk/qCSELK5M6239 intact-crc:52B8427DAC0EEC33|rigid:QUUPT5lTrBKxHIIpqK4ifM2Uffc false - sufficient binding region:102-417("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02482 uniprotkb:Q9N4L2 intact:EBI-314716|uniprotkb:P91912|ensemblmetazoa:W02D3.9.1|ensemblmetazoa:W02D3.9.2 intact:EBI-2006816|ensemblmetazoa:ZK993.1a.1 psi-mi:unc37_caeel(display_long)|uniprotkb:unc-37(gene name)|psi-mi:unc-37(display_short)|uniprotkb:esg(gene name synonym)|uniprotkb:W02D3.9(orf name)|uniprotkb:Uncoordinated protein 37(gene name synonym) psi-mi:q9n4l2_caeel(display_long)|uniprotkb:ceh-45(gene name)|psi-mi:ceh-45(display_short)|uniprotkb:CELE_ZK993.1(orf name)|uniprotkb:ZK993.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462419|imex:IM-11985-665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-4641265|refseq:NP_491932.1|wormbase:W02D3.9|reactome:R-CEL-3769402|ensemblmetazoa:W02D3.9.1(transcript)|ensemblmetazoa:W02D3.9.2(transcript)|ensemblmetazoa:WBGene00006773(gene)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008134"(transcription factor binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|dip:DIP-27333N|reactome:R-CEL-201722 refseq:NP_490823.1|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|wormbase:ZK993.1a|ensemblmetazoa:WBGene00022837(gene)|ensemblmetazoa:ZK993.1a.1(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+e4X3QH+GChhuO2oAhaNGVwnO/o6239 rogid:7Iey8Vkqv29PamcScQgOnDHC4As6239 intact-crc:2CA2D65F3D24C2FC|rigid:9phTle1hT8/t6qAaxDrST0s6vT0 false sufficient binding region:101-612("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39745-1 uniprotkb:Q17695 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 intact:EBI-321960|ensemblmetazoa:C06A8.5.1 psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:spdl1_caeel(display_long)|uniprotkb:spdl-1(gene name)|psi-mi:spdl-1(display_short)|uniprotkb:C06A8.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462429|imex:IM-11985-666 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) wormbase:C06A8.5|refseq:NP_495637.1|ensemblmetazoa:C06A8.5.1(transcript)|ensemblmetazoa:WBGene00015515(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1902423"(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|go:"GO:1905824"(positive regulation of mitotic sister chromatid arm separation)|dip:DIP-27271N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 rogid:g40O7KzMDsgC0rWt+1ukYir8zA46239 intact-crc:19F0AADBC9710F48|rigid:pLcLEtfuPa5q3SWOLigrsF6TLUM false - sufficient binding region:101-479("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34808-1 uniprotkb:P34808 intact:EBI-6458290|ensemblmetazoa:T01G9.5a.1 intact:EBI-323248|intact:EBI-521368|uniprotkb:Q8I4G6|ensemblmetazoa:T01G9.5a.1 psi-mi:p34808-1(display_long)|uniprotkb:Katanin p60 ATPase-containing subunit A1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:T01G9.5(orf name)|uniprotkb:mei-1(gene name)|psi-mi:mei-1(display_short) psi-mi:ktna1_caeel(display_long)|uniprotkb:mei-1(gene name)|psi-mi:mei-1(display_short)|uniprotkb:Katanin p60 ATPase-containing subunit A1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:T01G9.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462439|imex:IM-11985-667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T01G9.5a.1(transcript)|ensemblmetazoa:WBGene00003183(gene)|intact:EBI-323248(isoform-parent) refseq:NP_492257.1|refseq:NP_871793.1|wormbase:T01G9.5a|wormbase:T01G9.5b|ensemblmetazoa:T01G9.5a.1(transcript)|ensemblmetazoa:WBGene00003183(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000785"(chromatin)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051013"(microtubule severing)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0005813"(centrosome)|go:"GO:0071688"(striated muscle myosin thick filament assembly)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0090736"(MATH domain binding)|go:"GO:1902120"(negative regulation of meiotic spindle elongation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR028596|interpro:IPR041569|rcsb pdb:5WC0|rcsb pdb:5WC1|rcsb pdb:5WCB|rcsb pdb:6B5D|go:"GO:0005819"(spindle)|rcsb pdb:6UGD|rcsb pdb:6UGE|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|rcsb pdb:6UGF|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008017"(microtubule binding)|go:"GO:0008352"(katanin complex)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016853"(isomerase activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|dip:DIP-25343N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W8dzUByepgfcMfSsWiLQdK+/pus6239 rogid:W8dzUByepgfcMfSsWiLQdK+/pus6239 intact-crc:FEC810BCB381B685|rigid:wlgQ4B7KwlJrkdPEh625PoLr4eI false - sufficient binding region:101-472("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09436 uniprotkb:Q95XY1 intact:EBI-300562|ensemblmetazoa:AH6.5.1 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:mex6_caeel(display_long)|uniprotkb:mex-6(gene name)|psi-mi:mex-6(display_short)|uniprotkb:AH6.5(orf name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462449|imex:IM-11985-668 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:AH6.5.1(transcript)|ensemblmetazoa:WBGene00003231(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0005829"(cytosol)|refseq:NP_496043.1|wormbase:AH6.5|reactome:R-CEL-450385|dip:DIP-26165N refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oVKWJRS2uVN3eOW+qihqknx3WJM6239 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:6F58CF257415B118|rigid:yvZct5oW2BbJ6MjSCv7+lybqYAk false sufficient binding region:101-467("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09436 uniprotkb:Q65XX1 intact:EBI-300562|ensemblmetazoa:AH6.5.1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:mex6_caeel(display_long)|uniprotkb:mex-6(gene name)|psi-mi:mex-6(display_short)|uniprotkb:AH6.5(orf name) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462459|imex:IM-11985-669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:AH6.5.1(transcript)|ensemblmetazoa:WBGene00003231(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0005829"(cytosol)|refseq:NP_496043.1|wormbase:AH6.5|reactome:R-CEL-450385|dip:DIP-26165N refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:oVKWJRS2uVN3eOW+qihqknx3WJM6239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:692934DE8D9EBFCC|rigid:kR2+ct0BMX2OCoDJMWNj28gZBv8 false sufficient binding region:101-437("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17695 uniprotkb:O17666 intact:EBI-321960|ensemblmetazoa:C06A8.5.1 intact:EBI-317257|ensemblmetazoa:C45G3.1.1 psi-mi:spdl1_caeel(display_long)|uniprotkb:spdl-1(gene name)|psi-mi:spdl-1(display_short)|uniprotkb:C06A8.5(orf name) psi-mi:o17666_caeel(display_long)|uniprotkb:aspm-1(gene name)|psi-mi:aspm-1(display_short)|uniprotkb:C45G3.1(orf name)|uniprotkb:CELE_C45G3.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462469|imex:IM-11985-670 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C06A8.5|refseq:NP_495637.1|ensemblmetazoa:C06A8.5.1(transcript)|ensemblmetazoa:WBGene00015515(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1902423"(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|go:"GO:1905824"(positive regulation of mitotic sister chromatid arm separation)|dip:DIP-27271N refseq:NP_492467.1|wormbase:C45G3.1|ensemblmetazoa:C45G3.1.1(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|ensemblmetazoa:WBGene00008107(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0051233"(spindle midzone)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051296"(establishment of meiotic spindle orientation)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|dip:DIP-24587N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g40O7KzMDsgC0rWt+1ukYir8zA46239 rogid:3HsZ5W1fxEraEGP5zR4dmX+8mo06239 intact-crc:BADE66E2DD2156FD|rigid:1FwvhtYX9QeR2x6g+l7954nqnYc false sufficient binding region:101-351("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EBE3 uniprotkb:G5EBE3 intact:EBI-2003873|ensemblmetazoa:F55F8.4.1|ensemblmetazoa:F55F8.4.2 intact:EBI-2003873|ensemblmetazoa:F55F8.4.1|ensemblmetazoa:F55F8.4.2 psi-mi:g5ebe3_caeel(display_long)|uniprotkb:cir-1(gene name)|psi-mi:cir-1(display_short)|uniprotkb:CELE_F55F8.4(orf name)|uniprotkb:F55F8.4(orf name) psi-mi:g5ebe3_caeel(display_long)|uniprotkb:cir-1(gene name)|psi-mi:cir-1(display_short)|uniprotkb:CELE_F55F8.4(orf name)|uniprotkb:F55F8.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462479|imex:IM-11985-671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P91342(uniprot-removed-ac)|interpro:IPR040014|interpro:IPR019339|refseq:NP_491654.1|wormbase:F55F8.4|ensemblmetazoa:F55F8.4.1(transcript)|ensemblmetazoa:F55F8.4.2(transcript)|ensemblmetazoa:WBGene00018892(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048477"(oogenesis) uniprotkb:P91342(uniprot-removed-ac)|interpro:IPR040014|interpro:IPR019339|refseq:NP_491654.1|wormbase:F55F8.4|ensemblmetazoa:F55F8.4.1(transcript)|ensemblmetazoa:F55F8.4.2(transcript)|ensemblmetazoa:WBGene00018892(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0043621"(protein self-association)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048477"(oogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WLmi45oz5gYwR5X4PaJ9/kUom1o6239 rogid:WLmi45oz5gYwR5X4PaJ9/kUom1o6239 intact-crc:ED67936A6131CD72|rigid:bCHby3vd87/wZXa/c7jU53zPh80 false - sufficient binding region:101-303("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17695 uniprotkb:Q9GT24 intact:EBI-321960|ensemblmetazoa:C06A8.5.1 intact:EBI-323555|uniprotkb:O01903|ensemblmetazoa:F59E12.2.1|ensemblmetazoa:F59E12.2.2 psi-mi:spdl1_caeel(display_long)|uniprotkb:spdl-1(gene name)|psi-mi:spdl-1(display_short)|uniprotkb:C06A8.5(orf name) psi-mi:zyg1_caeel(display_long)|uniprotkb:zyg-1(gene name)|psi-mi:zyg-1(display_short)|uniprotkb:F59E12.2(orf name)|uniprotkb:Zygote defective protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462489|imex:IM-11985-672 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C06A8.5|refseq:NP_495637.1|ensemblmetazoa:C06A8.5.1(transcript)|ensemblmetazoa:WBGene00015515(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1902423"(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|go:"GO:1905824"(positive regulation of mitotic sister chromatid arm separation)|dip:DIP-27271N refseq:NP_495103.1|wormbase:F59E12.2|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0051225"(spindle assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|ensemblmetazoa:F59E12.2.1(transcript)|ensemblmetazoa:F59E12.2.2(transcript)|ensemblmetazoa:WBGene00006988(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0106311"|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1904779"(regulation of protein localization to centrosome)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR040733|interpro:IPR040734|rcsb pdb:4NKB|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-24892N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g40O7KzMDsgC0rWt+1ukYir8zA46239 rogid:bW56U+tOCdP8UXKTudspR9Oi4/Q6239 intact-crc:D6A42BBB0A3C0886|rigid:H7Ghy5KfDSqohx6Km4wJ+px4JQ8 false sufficient binding region:101-301("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17695 uniprotkb:P91457 intact:EBI-321960|ensemblmetazoa:C06A8.5.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:spdl1_caeel(display_long)|uniprotkb:spdl-1(gene name)|psi-mi:spdl-1(display_short)|uniprotkb:C06A8.5(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462499|imex:IM-11985-673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C06A8.5|refseq:NP_495637.1|ensemblmetazoa:C06A8.5.1(transcript)|ensemblmetazoa:WBGene00015515(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901970"(positive regulation of mitotic sister chromatid separation)|go:"GO:1902423"(regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905561"(positive regulation of kinetochore assembly)|go:"GO:1905824"(positive regulation of mitotic sister chromatid arm separation)|dip:DIP-27271N refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:g40O7KzMDsgC0rWt+1ukYir8zA46239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:B96932A8C89EE79D|rigid:LQhAoLDRpqN7yYy6GDi/mD7xcmg false sufficient binding region:101-251("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL3 uniprotkb:Q22469 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 intact:EBI-329638|ensemblmetazoa:T13H5.4.1 psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:q22469_caeel(display_long)|uniprotkb:T13H5.4(orf name)|uniprotkb:CELE_T13H5.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462509|imex:IM-11985-674 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 refseq:NP_495799.1|wormbase:T13H5.4|reactome:R-CEL-72163|dip:DIP-25197N|ensemblmetazoa:T13H5.4.1(transcript)|ensemblmetazoa:WBGene00011758(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 rogid:GLuSG37nqmw6DTs2aINb+mMiwi06239 intact-crc:F99AD0ECFF77E47F|rigid:0g1a+pB2+8Eb6fGrngE3qKHSJxY false sufficient binding region:101-247("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21021 uniprotkb:Q22747 intact:EBI-2003933|ensemblmetazoa:F59A2.1a.1|ensemblmetazoa:F59A2.1a.2|ensemblmetazoa:F59A2.1a.3 intact:EBI-324189|ensemblmetazoa:T24F1.2.1 psi-mi:q21021_caeel(display_long)|uniprotkb:npp-9(gene name)|psi-mi:npp-9(display_short)|uniprotkb:CELE_F59A2.1(orf name)|uniprotkb:F59A2.1(orf name) psi-mi:tm201_caeel(display_long)|uniprotkb:Spindle-associated membrane protein homolog(gene name synonym)|uniprotkb:T24F1.2(orf name)|uniprotkb:samp-1(gene name)|psi-mi:samp-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462519|imex:IM-11985-675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497703.1|wormbase:F59A2.1a|dip:DIP-26904N|ensemblmetazoa:F59A2.1a.1(transcript)|ensemblmetazoa:F59A2.1a.2(transcript)|ensemblmetazoa:F59A2.1a.3(transcript)|ensemblmetazoa:WBGene00003795(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_496416.1|wormbase:T24F1.2|ensemblmetazoa:T24F1.2.1(transcript)|ensemblmetazoa:WBGene00011994(gene)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR018617|interpro:IPR040041|go:"GO:0005639"(integral component of nuclear inner membrane)|dip:DIP-24366N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:m//Dnktvrf6Dhiwf97MJUgEimdY6239 rogid:QdowhtFqJuhARa50QbUTk2GlgDw6239 intact-crc:309689E4B3E38EDA|rigid:DKWQgB7LYlu3NhJGOab2ECPHbKM false - sufficient binding region:101-198("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5U1 uniprotkb:Q22747 intact:EBI-2005375|ensemblmetazoa:T22F3.3a.1 intact:EBI-324189|ensemblmetazoa:T24F1.2.1 psi-mi:q9n5u1_caeel(display_long)|uniprotkb:pygl-1(gene name)|psi-mi:pygl-1(display_short)|uniprotkb:CELE_T22F3.3(orf name)|uniprotkb:T22F3.3(orf name) psi-mi:tm201_caeel(display_long)|uniprotkb:Spindle-associated membrane protein homolog(gene name synonym)|uniprotkb:T24F1.2(orf name)|uniprotkb:samp-1(gene name)|psi-mi:samp-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462529|imex:IM-11985-676 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504007.1|wormbase:T22F3.3a|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|reactome:R-CEL-70221|interpro:IPR035090|ensemblmetazoa:T22F3.3a.1(transcript)|ensemblmetazoa:WBGene00020696(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity) refseq:NP_496416.1|wormbase:T24F1.2|ensemblmetazoa:T24F1.2.1(transcript)|ensemblmetazoa:WBGene00011994(gene)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR018617|interpro:IPR040041|go:"GO:0005639"(integral component of nuclear inner membrane)|dip:DIP-24366N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hxlfa3e+4GTuwc4kabxrVxbDecs6239 rogid:QdowhtFqJuhARa50QbUTk2GlgDw6239 intact-crc:217B476F92FA5938|rigid:rM5wectawwTxsu8buNQlHClRQPs false - sufficient binding region:101-198("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39745-1 intact:EBI-6458701 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 intact:EBI-6306432 psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:ebi6306432(display_short)|psi-mi:EBI-6458701(display_long)|intact:Y57A10A.24x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462539|imex:IM-11985-677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 - intact-crc:630DA6A29627D3FF false - sufficient binding region:100-437("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20052 intact:EBI-6458701 intact:EBI-314913|ensemblmetazoa:F35G12.9.1|ensemblmetazoa:F35G12.9.2 intact:EBI-6306432 psi-mi:apc11_caeel(display_long)|uniprotkb:apc-11(gene name)|psi-mi:apc-11(display_short)|uniprotkb:F35G12.9(orf name) psi-mi:ebi6306432(display_short)|psi-mi:EBI-6458701(display_long)|intact:Y57A10A.24x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462549|imex:IM-11985-678 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497937.1|wormbase:F35G12.9|ensemblmetazoa:F35G12.9.1(transcript)|ensemblmetazoa:F35G12.9.2(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|ensemblmetazoa:WBGene00000145(gene)|dip:DIP-24995N|reactome:R-CEL-983168 - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:11SdvWjkFNUyCv4arePb6BEXKEg6239 - intact-crc:52374BF13A04C2F9 false - sufficient binding region:100-387("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95Y13 intact:EBI-6458701 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 intact:EBI-6306432 psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:ebi6306432(display_short)|psi-mi:EBI-6458701(display_long)|intact:Y57A10A.24x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462559|imex:IM-11985-679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 - intact-crc:3C2B2CD061EC2A90 false - sufficient binding region:100-387("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:Q17606 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-2002036|ensemblmetazoa:C03D6.8.1 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:rlp24_caeel(display_long)|uniprotkb:rpl-24.2(gene name)|psi-mi:rpl-24.2(display_short)|uniprotkb:C03D6.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462569|imex:IM-11985-680 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 interpro:IPR011017(TRASH)|refseq:NP_492572.1|wormbase:C03D6.8|interpro:IPR023442|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR038630|ensemblmetazoa:C03D6.8.1(transcript)|ensemblmetazoa:WBGene00004437(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:1902626"(assembly of large subunit precursor of preribosome) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:LO76/rNzWgcVqK1QEjf/8yj3YLo6239 intact-crc:48542E9F58DB3E68|rigid:SaIJurzB3a08htKlv6gFwXwWWJA false sufficient binding region:100-260("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:P30642 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-311981|ensemblmetazoa:R08D7.3.1 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:eif3d_caeel(display_long)|uniprotkb:R08D7.3(orf name)|uniprotkb:eif-3.D(gene name)|psi-mi:eif-3.D(display_short)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462579|imex:IM-11985-681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 reactome:R-CEL-72649|ensemblmetazoa:R08D7.3.1(transcript)|ensemblmetazoa:WBGene00001227(gene)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0098808"(mRNA cap binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|refseq:NP_498984.1|wormbase:R08D7.3|reactome:R-CEL-156827|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|dip:DIP-25819N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:CvW4IPXX62lvTWXOvGSZttuD3cs6239 intact-crc:CFCF37D850D0D718|rigid:O5D/v9//eifN5iObV6GTQG9DprI false sufficient binding region:100-260("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECG0 uniprotkb:P91457 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462589|imex:IM-11985-682 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:D7F6FB2F17C5E12F|rigid:o00aHdb+AnyM0SI7Ay5uL/e0A9s false sufficient binding region:100-260("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19335 uniprotkb:G5ECL3 intact:EBI-329629|ensemblmetazoa:F11A10.2.1 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 psi-mi:q19335_caeel(display_long)|uniprotkb:F11A10.2(orf name)|uniprotkb:repo-1(gene name)|psi-mi:repo-1(display_short)|uniprotkb:CELE_F11A10.2(orf name) psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462599|imex:IM-11985-683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502290.1|wormbase:F11A10.2|reactome:R-CEL-72163|dip:DIP-26535N|ensemblmetazoa:F11A10.2.1(transcript)|ensemblmetazoa:WBGene00008683(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0008270"(zinc ion binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR031781|interpro:IPR036236 interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:yL27iBYsk9+fnmokFlhCtfMsQDA6239 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 intact-crc:2D82499032C163ED|rigid:xZozEesGuE+42QGXDTdlQJZAKKo false sufficient binding region:100-222("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GT24 uniprotkb:Q18282 intact:EBI-323555|uniprotkb:O01903|ensemblmetazoa:F59E12.2.1|ensemblmetazoa:F59E12.2.2 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 psi-mi:zyg1_caeel(display_long)|uniprotkb:zyg-1(gene name)|psi-mi:zyg-1(display_short)|uniprotkb:F59E12.2(orf name)|uniprotkb:Zygote defective protein 1(gene name synonym) psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462609|imex:IM-11985-684 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495103.1|wormbase:F59E12.2|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0051225"(spindle assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|ensemblmetazoa:F59E12.2.1(transcript)|ensemblmetazoa:F59E12.2.2(transcript)|ensemblmetazoa:WBGene00006988(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0106311"|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1904779"(regulation of protein localization to centrosome)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR040733|interpro:IPR040734|rcsb pdb:4NKB|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-24892N refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bW56U+tOCdP8UXKTudspR9Oi4/Q6239 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 intact-crc:425B29BDBF38B38E|rigid:FHMkWxxTFFTyEysQtZ93R7oTsG8 false - sufficient binding region:100-193("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44740 uniprotkb:P34808-1 intact:EBI-323243|ensemblmetazoa:F57B10.12.1 intact:EBI-6458290|ensemblmetazoa:T01G9.5a.1 psi-mi:mei2_caeel(display_long)|uniprotkb:mei-2(gene name)|psi-mi:mei-2(display_short)|uniprotkb:F57B10.12(orf name) psi-mi:p34808-1(display_long)|uniprotkb:Katanin p60 ATPase-containing subunit A1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:T01G9.5(orf name)|uniprotkb:mei-1(gene name)|psi-mi:mei-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462619|imex:IM-11985-685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491894.1|wormbase:F57B10.12|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008352"(katanin complex)|ensemblmetazoa:F57B10.12.1(transcript)|ensemblmetazoa:WBGene00003184(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001940"(male pronucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051013"(microtubule severing)|go:"GO:0051301"(cell division)|interpro:IPR028021|dip:DIP-27215N ensemblmetazoa:T01G9.5a.1(transcript)|ensemblmetazoa:WBGene00003183(gene)|intact:EBI-323248(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:HkLWJzdRNw3NMipE4Q42A4cT7ks6239 rogid:W8dzUByepgfcMfSsWiLQdK+/pus6239 intact-crc:4C1B5B77203E23B2|rigid:vzxBsu4jJ8pZCX+WflSL9sgsDIk false sufficient binding region:100-130("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O76840-3 uniprotkb:Q9XVP0 intact:EBI-1012546|ensemblmetazoa:C37C3.6c.1|ensemblmetazoa:C37C3.6c.2 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 psi-mi:o76840-3(display_long)|uniprotkb:mig-6(gene name)|psi-mi:mig-6(display_short)|uniprotkb:ppn-1(gene name synonym)|uniprotkb:Abnormal cell migration protein 6(gene name synonym)|uniprotkb:C37C3.6(orf name) psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462629|imex:IM-11985-686 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-312512(o76840_caeel)|ensemblmetazoa:C37C3.6c.1(transcript)|ensemblmetazoa:C37C3.6c.2(transcript)|ensemblmetazoa:WBGene00003242(gene) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:8LazNnXahKhFJ4Cvl4drbTb98l06239 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 intact-crc:12A42B6840B87D71|rigid:8DiY0Mh2X/UXO/iqbO618Nxt2is false sufficient binding region:866-1487("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39745-1 uniprotkb:Q8I4M5 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 intact:EBI-322416|ensemblmetazoa:C36B1.8b.1|uniprotkb:C3UPA2|uniprotkb:C6KRM2|uniprotkb:Q93342 psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:gls1_caeel(display_long)|uniprotkb:C36B1.8(orf name)|uniprotkb:gls-1(gene name)|psi-mi:gls-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462639|imex:IM-11985-687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) refseq:NP_492365.3|refseq:NP_871882.2|wormbase:C36B1.8b|ensemblmetazoa:C36B1.8b.1(transcript)|ensemblmetazoa:WBGene00007975(gene)|go:"GO:0005844"(polysome)|go:"GO:0043186"(P granule)|go:"GO:0051321"(meiotic cell cycle)|wormbase:C36B1.8a|wormbase:C36B1.8c|refseq:NP_001250878.1|dip:DIP-25830N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 rogid:iZUWnnSoSeaAyg7TQbG6lUk+ni86239 intact-crc:722A0ACE40EEAEF9|rigid:auSM3nd6J2oim4vOcx2J/Twveu4 false - sufficient binding region:602-1052("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:Q8I4M5 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-322416|ensemblmetazoa:C36B1.8b.1|uniprotkb:C3UPA2|uniprotkb:C6KRM2|uniprotkb:Q93342 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:gls1_caeel(display_long)|uniprotkb:C36B1.8(orf name)|uniprotkb:gls-1(gene name)|psi-mi:gls-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462649|imex:IM-11985-688 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 refseq:NP_492365.3|refseq:NP_871882.2|wormbase:C36B1.8b|ensemblmetazoa:C36B1.8b.1(transcript)|ensemblmetazoa:WBGene00007975(gene)|go:"GO:0005844"(polysome)|go:"GO:0043186"(P granule)|go:"GO:0051321"(meiotic cell cycle)|wormbase:C36B1.8a|wormbase:C36B1.8c|refseq:NP_001250878.1|dip:DIP-25830N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:iZUWnnSoSeaAyg7TQbG6lUk+ni86239 intact-crc:DD82CF443B1B0E6E|rigid:qNJhexAmXXUa0fWG0NNldqZO444 false - sufficient binding region:602-1052("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20052 uniprotkb:P34514 intact:EBI-314913|ensemblmetazoa:F35G12.9.1|ensemblmetazoa:F35G12.9.2 intact:EBI-321211|uniprotkb:P34513|ensemblmetazoa:K06H7.6.1 psi-mi:apc11_caeel(display_long)|uniprotkb:apc-11(gene name)|psi-mi:apc-11(display_short)|uniprotkb:F35G12.9(orf name) psi-mi:anc2_caeel(display_long)|uniprotkb:apc-2(gene name)|psi-mi:apc-2(display_short)|uniprotkb:K06H7.6/K06H7.5(orf name)|uniprotkb:Cyclosome subunit 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462659|imex:IM-11985-689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497937.1|wormbase:F35G12.9|ensemblmetazoa:F35G12.9.1(transcript)|ensemblmetazoa:F35G12.9.2(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|ensemblmetazoa:WBGene00000145(gene)|dip:DIP-24995N|reactome:R-CEL-983168 refseq:NP_498762.2|wormbase:K06H7.6|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|ensemblmetazoa:K06H7.6.1(transcript)|interpro:IPR014786(Anaphase promoting complex subunit 2)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|ensemblmetazoa:WBGene00000143(gene)|interpro:IPR036317|interpro:IPR036388|reactome:R-CEL-983168|interpro:IPR044554 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:11SdvWjkFNUyCv4arePb6BEXKEg6239 rogid:5aEjMp7tIE0ClHdaPpdw0mJBHmg6239 intact-crc:3E9E55C6BAC39C06|rigid:Z7b8uy/rKw863jbqVMeak7K41GY false - sufficient binding region:534-731("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U2W9 uniprotkb:O62193 intact:EBI-2003213|ensemblmetazoa:Y113G7B.24a.1 intact:EBI-2003348|ensemblmetazoa:F31C3.5.1 psi-mi:q9u2w9_caeel(display_long)|uniprotkb:Y113G7B.24(orf name)|uniprotkb:sld-5(gene name)|psi-mi:sld-5(display_short)|uniprotkb:CELE_Y113G7B.24(orf name) psi-mi:psf2_caeel(display_long)|uniprotkb:psf-2(gene name)|psi-mi:psf-2(display_short)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:F31C3.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462669|imex:IM-11985-690 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR038749|wormbase:Y113G7B.24a|interpro:IPR008591(GINS complex, Sld5 component)|refseq:NP_001256903.1|interpro:IPR031633|interpro:IPR036224|reactome:R-CEL-176974|ensemblmetazoa:WBGene00013768(gene)|ensemblmetazoa:Y113G7B.24a.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication) refseq:NP_493627.1|wormbase:F31C3.5|interpro:IPR021151|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR036224|reactome:R-CEL-176974|ensemblmetazoa:F31C3.5.1(transcript)|ensemblmetazoa:WBGene00009287(gene)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006260"(DNA replication) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tmt0MlWaEPakeV8cNoLk6bnmK406239 rogid:cPoxdhLMo0pdtkvVduAtKY91uWw6239 intact-crc:96167C66FD702174|rigid:YlIMXLTnbeGfPCNueix1CUdKIsE false sufficient binding region:5-141("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39745-1 uniprotkb:Q17339 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 intact:EBI-328239|uniprotkb:O02540|ensemblmetazoa:T23G11.3.1|ensemblmetazoa:T23G11.3.2 psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:gld1_caeel(display_long)|uniprotkb:gld-1(gene name)|psi-mi:gld-1(display_short)|uniprotkb:T23G11.3(orf name)|uniprotkb:Defective in germ line development protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462679|imex:IM-11985-691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) refseq:NP_492143.1|wormbase:T23G11.3|dip:DIP-24870N|ensemblmetazoa:T23G11.3.1(transcript)|ensemblmetazoa:T23G11.3.2(transcript)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031119|interpro:IPR032377|interpro:IPR036612|rcsb pdb:2MJH|rcsb pdb:3K6T|rcsb pdb:3KBL|rcsb pdb:4JVY|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0043186"(P granule)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:2000196"(positive regulation of female gonad development)|ensemblmetazoa:WBGene00001595(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 rogid:x5WDIiYEeeRlvXFLKdJA3bUJ1bA6239 intact-crc:21ADA7FC4E5B30BF|rigid:Yx3XQ+BroKNgX6/rXoqcq1CyVo0 false - sufficient binding region:51-198("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q17339 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-328239|uniprotkb:O02540|ensemblmetazoa:T23G11.3.1|ensemblmetazoa:T23G11.3.2 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:gld1_caeel(display_long)|uniprotkb:gld-1(gene name)|psi-mi:gld-1(display_short)|uniprotkb:T23G11.3(orf name)|uniprotkb:Defective in germ line development protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462689|imex:IM-11985-692 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) refseq:NP_492143.1|wormbase:T23G11.3|dip:DIP-24870N|ensemblmetazoa:T23G11.3.1(transcript)|ensemblmetazoa:T23G11.3.2(transcript)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031119|interpro:IPR032377|interpro:IPR036612|rcsb pdb:2MJH|rcsb pdb:3K6T|rcsb pdb:3KBL|rcsb pdb:4JVY|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030716"(oocyte fate determination)|go:"GO:0043186"(P granule)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:1905936"(regulation of germ cell proliferation)|go:"GO:2000196"(positive regulation of female gonad development)|ensemblmetazoa:WBGene00001595(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:x5WDIiYEeeRlvXFLKdJA3bUJ1bA6239 intact-crc:EDA64E6A9245FEDF|rigid:mGG/SoU+DX/QapYmObhTGZe3G8w false - sufficient binding region:51-198("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9U489 uniprotkb:Q95Y13 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462699|imex:IM-11985-693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 intact-crc:8200692E641E6BDF|rigid:tOV2sT1Yw3ZQOhdhdWLsyx+xC3Y false sufficient binding region:470-936("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7YTG9 uniprotkb:Q9U489 intact:EBI-2003102|ensemblmetazoa:F11A10.8.1|ensemblmetazoa:F11A10.8.2 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:q7ytg9_caeel(display_long)|uniprotkb:cpsf-4(gene name)|psi-mi:cpsf-4(display_short)|uniprotkb:CELE_F11A10.8(orf name)|uniprotkb:F11A10.8(orf name) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462709|imex:IM-11985-694 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023126.1|wormbase:F11A10.8|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|interpro:IPR036855|interpro:IPR036875|reactome:R-CEL-73856|ensemblmetazoa:F11A10.8.1(transcript)|ensemblmetazoa:F11A10.8.2(transcript)|ensemblmetazoa:WBGene00044329(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation) reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:hFzrsuwJxyQatMLkejzDei/oxYw6239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:B7EE4FF548BB2E49|rigid:V1szYzk6sNig9vx5u3aCQkAIXh4 false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34470 uniprotkb:Q9U489 intact:EBI-331027|ensemblmetazoa:F58A4.3.1 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:hcp3_caeel(display_long)|uniprotkb:hcp-3(gene name)|psi-mi:hcp-3(display_short)|uniprotkb:F58A4.3(orf name)|uniprotkb:Holocentric chromosome-binding protein 3(gene name synonym)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:CeCENP-A(gene name synonym) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462719|imex:IM-11985-695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499128.1|wormbase:F58A4.3|dip:DIP-27043N|ensemblmetazoa:F58A4.3.1(transcript)|ensemblmetazoa:WBGene00001831(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070199"(establishment of protein localization to chromosome)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098813"(nuclear chromosome segregation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|go:"GO:0046603"(negative regulation of mitotic centrosome separation) reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s6leDsHmucRjGMcKCxqMqah1h4Q6239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:16C8AD573926552D|rigid:zR1CEDuh5TQ7qmSuosudCIRr+1Y false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34509 uniprotkb:Q9U489 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462729|imex:IM-11985-696 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:CB5ED2DDA1F49E29|rigid:dOFT/4To+9UPAUXNidIBcDZFGVM false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21341 uniprotkb:Q9U489 intact:EBI-1811800|ensemblmetazoa:K08E7.3.1 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:let99_caeel(display_long)|uniprotkb:let-99(gene name)|psi-mi:let-99(display_short)|uniprotkb:Lethal protein 99(gene name synonym)|uniprotkb:K08E7.3(orf name) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462739|imex:IM-11985-697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502407.1|wormbase:K08E7.3|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|reactome:R-CEL-8980692|reactome:R-CEL-9013148|reactome:R-CEL-9013149|reactome:R-CEL-9013404|reactome:R-CEL-9013405|reactome:R-CEL-9013406|reactome:R-CEL-9013409|reactome:R-CEL-9013420|reactome:R-CEL-9013424|reactome:R-CEL-9035034|interpro:IPR036388|interpro:IPR036390|ensemblmetazoa:K08E7.3.1(transcript)|ensemblmetazoa:WBGene00002368(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005938"(cell cortex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051301"(cell division) reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:rARdgvl4l+tXuawwY+bTaTRQNBg6239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:771C6D2BEA3428F7|rigid:dMrp1ZmKMwA2xaXt7KN7oyg9yTE false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09410 uniprotkb:Q9U489 intact:EBI-2004414|ensemblmetazoa:K10D2.4.1 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:emb1_caeel(display_long)|uniprotkb:emb-1(gene name)|psi-mi:emb-1(display_short)|uniprotkb:Abnormal embryogenesis protein 1(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 16 homolog(gene name synonym)|uniprotkb:apc-16(gene name synonym)|uniprotkb:K10D2.4(orf name) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462749|imex:IM-11985-698 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498098.1|wormbase:K10D2.4|ensemblmetazoa:K10D2.4.1(transcript)|ensemblmetazoa:WBGene00019630(gene)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:FEUHkBhYLsPjrKrBBV6Ik3hDbQw6239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:C10438BAC2A6A59D|rigid:QxHSUXp+POoXSD5wwRqtWpIPtcg false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:Q9U489 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462759|imex:IM-11985-699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:E5A416F735CC2E9D|rigid:kXSzk5eyYXDXRPiwqmf9ktk2JT8 false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95QC4 uniprotkb:Q9U489 intact:EBI-331795|uniprotkb:Q9U1S0|ensemblmetazoa:Y79H2A.11a.1 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:dclk_caeel(display_long)|uniprotkb:zyg-8(gene name)|psi-mi:zyg-8(display_short)|uniprotkb:Y79H2A.11(orf name)|uniprotkb:Doublecortin-like and CAM kinase-like protein(gene name synonym) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462769|imex:IM-11985-700 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499571.2|wormbase:Y79H2A.11|dip:DIP-25008N|ensemblmetazoa:WBGene00006993(gene)|ensemblmetazoa:Y79H2A.11a.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR036572 reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5IBxxKBhEODxkMhwHoeTECHbglw6239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:E35D218344E78C2C|rigid:6d4iZFqt6r7HaHuSkJeNl58MLBA false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23593 uniprotkb:Q9U489 intact:EBI-6460566|ensemblmetazoa:ZK792.2.1|ensemblmetazoa:ZK792.2.2|ensemblmetazoa:ZK792.2.3 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:inx8_caeel(display_long)|uniprotkb:Protein opu-8(gene name synonym)|uniprotkb:opu-8(gene name synonym)|uniprotkb:ZK792.2(orf name)|uniprotkb:inx-8(gene name)|psi-mi:inx-8(display_short) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462779|imex:IM-11985-701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00002130(gene)|ensemblmetazoa:ZK792.2.1(transcript)|ensemblmetazoa:ZK792.2.2(transcript)|ensemblmetazoa:ZK792.2.3(transcript)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0006811"(ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036093"(germ cell proliferation)|go:"GO:0055077"(gap junction hemi-channel activity)|interpro:IPR000990(Innexin)|refseq:NP_502209.1|wormbase:ZK792.2 reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:5X1kqdk1VN+p4aaWMmR0YoK5KTs6239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:7D9216319E35C015|rigid:EgluxXbJ/BOIBBAVX5dEKmIm2WY false - sufficient binding region:470-671("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q9U489 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-895855|uniprotkb:Q9U490|ensemblmetazoa:C12C8.3a.1|ensemblmetazoa:C12C8.3a.2 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:lin41_caeel(display_long)|uniprotkb:lin-41(gene name)|psi-mi:lin-41(display_short)|uniprotkb:C12C8.3(orf name)|uniprotkb:Abnormal cell lineage protein 41(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462789|imex:IM-11985-702 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) reactome:R-CEL-6798695|rcsb pdb:4UMG|refseq:NP_001020998.1|refseq:NP_001020999.1|wormbase:C12C8.3a|wormbase:C12C8.3b|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR017868|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000315(Zinc finger, B-box)|reactome:R-CEL-983168|ensemblmetazoa:C12C8.3a.1(transcript)|ensemblmetazoa:C12C8.3a.2(transcript)|ensemblmetazoa:WBGene00003026(gene)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007276"(gamete generation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030371"(translation repressor activity)|go:"GO:0035198"(miRNA binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0110037"(regulation of nematode male tail tip morphogenesis)|go:"GO:1990124"(messenger ribonucleoprotein complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:EP/KS7VWQxyM20JJlPV+WztM2oI6239 intact-crc:78B7F78E9C0F522F|rigid:4lxayZ4wnQ7Fprbb+2CVEe8bcTY false - sufficient binding region:470-1147("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01488 uniprotkb:Q21444 intact:EBI-320537|ensemblmetazoa:C13F10.2.1 intact:EBI-323200|uniprotkb:Q17752|ensemblmetazoa:C06G3.10.1 psi-mi:o01488_caeel(display_long)|uniprotkb:kxd-1(gene name)|psi-mi:kxd-1(display_short)|uniprotkb:C13F10.2(orf name)|uniprotkb:CELE_C13F10.2(orf name) psi-mi:cog2_caeel(display_long)|uniprotkb:C06G3.10(orf name)|uniprotkb:ldlc(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 2(gene name synonym)|uniprotkb:LDLC protein homolog(gene name synonym)|uniprotkb:cogc-2(gene name)|psi-mi:cogc-2(display_short)|uniprotkb:cog-2(gene name synonym)|uniprotkb:cgo-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462799|imex:IM-11985-703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504831.1|wormbase:C13F10.2|ensemblmetazoa:C13F10.2.1(transcript)|ensemblmetazoa:WBGene00015742(gene)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|dip:DIP-27148N refseq:NP_501092.1|wormbase:C06G3.10|reactome:R-CEL-6811438|ensemblmetazoa:C06G3.10.1(transcript)|ensemblmetazoa:WBGene00000585(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035262"(gonad morphogenesis)|interpro:IPR009316(COG complex component, COG2)|interpro:IPR024602|interpro:IPR024603|reactome:R-CEL-6807878|dip:DIP-26998N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZX/rck9tSHblPGJKegKAjZiqxeA6239 rogid:6ScuvFlYAvovxUwKzV2HjJ3gQYU6239 intact-crc:A9BDEE375A15C64B|rigid:9Zr2XenZHAREeG3AgAoRSRCijr8 false - sufficient binding region:3-681("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21444 uniprotkb:Q95XZ0-2 intact:EBI-323200|uniprotkb:Q17752|ensemblmetazoa:C06G3.10.1 intact:EBI-2005340|ensemblmetazoa:Y51H7C.6b.1 psi-mi:cog2_caeel(display_long)|uniprotkb:C06G3.10(orf name)|uniprotkb:ldlc(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 2(gene name synonym)|uniprotkb:LDLC protein homolog(gene name synonym)|uniprotkb:cogc-2(gene name)|psi-mi:cogc-2(display_short)|uniprotkb:cog-2(gene name synonym)|uniprotkb:cgo-2(gene name synonym) psi-mi:q95xz0-2(display_long)|uniprotkb:Component of oligomeric Golgi complex 4(gene name synonym)|uniprotkb:Y51H7C.6(orf name)|uniprotkb:cogc-4(gene name)|psi-mi:cogc-4(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462809|imex:IM-11985-704 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501092.1|wormbase:C06G3.10|reactome:R-CEL-6811438|ensemblmetazoa:C06G3.10.1(transcript)|ensemblmetazoa:WBGene00000585(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035262"(gonad morphogenesis)|interpro:IPR009316(COG complex component, COG2)|interpro:IPR024602|interpro:IPR024603|reactome:R-CEL-6807878|dip:DIP-26998N intact:EBI-2006014(isoform-parent)|ensemblmetazoa:WBGene00021784(gene)|ensemblmetazoa:Y51H7C.6b.1(transcript) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:6ScuvFlYAvovxUwKzV2HjJ3gQYU6239 rogid:qLDLooNSqRuzYbQ9GW4iw7BTajE6239 intact-crc:9F584ED3824D0D48|rigid:d6se5VntgTeOJu8rMLiDRhRVJ1g false sufficient binding region:3-681("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q2V0X4 uniprotkb:Q21444 intact:EBI-6456854 intact:EBI-323200|uniprotkb:Q17752|ensemblmetazoa:C06G3.10.1 psi-mi:q2v0x4_caeel(display_long)|uniprotkb:cogc-3(gene name)|psi-mi:cogc-3(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 3(gene name synonym) psi-mi:cog2_caeel(display_long)|uniprotkb:C06G3.10(orf name)|uniprotkb:ldlc(gene name synonym)|uniprotkb:Component of oligomeric Golgi complex 2(gene name synonym)|uniprotkb:LDLC protein homolog(gene name synonym)|uniprotkb:cogc-2(gene name)|psi-mi:cogc-2(display_short)|uniprotkb:cog-2(gene name synonym)|uniprotkb:cgo-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462819|imex:IM-11985-705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007265(Sec34-like protein) refseq:NP_501092.1|wormbase:C06G3.10|reactome:R-CEL-6811438|ensemblmetazoa:C06G3.10.1(transcript)|ensemblmetazoa:WBGene00000585(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035262"(gonad morphogenesis)|interpro:IPR009316(COG complex component, COG2)|interpro:IPR024602|interpro:IPR024603|reactome:R-CEL-6807878|dip:DIP-26998N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:G/tGsp4WwyIUGdFnfOzoBMkgOrM6239 rogid:6ScuvFlYAvovxUwKzV2HjJ3gQYU6239 intact-crc:17ADF8F938195B06|rigid:p6/tmqyvvex3/GfXfs+zKlllWGM false - sufficient binding region:3-681("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11141 uniprotkb:G5ECG0 intact:EBI-2006327|uniprotkb:P91135|ensemblmetazoa:C37H5.8.1 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:hsp6_caeel(display_long)|uniprotkb:hsp-6(gene name)|psi-mi:hsp-6(display_short)|uniprotkb:hsp70f(gene name synonym)|uniprotkb:C37H5.8(orf name)|uniprotkb:Heat shock 70 kDa protein F, mitochondrial(gene name synonym)|uniprotkb:mot-2(gene name synonym) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462829|imex:IM-11985-706 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043129|refseq:NP_504291.1|wormbase:C37H5.8|interpro:IPR012725(Chaperone DnaK)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3DQG|reactome:R-CEL-3371453|interpro:IPR029047|interpro:IPR029048|ensemblmetazoa:C37H5.8.1(transcript)|ensemblmetazoa:WBGene00002010(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding) interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mr6DFT7Fpkxrq2KsDDyXWGxU/+E6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:9D6E27E419CE802F|rigid:7OmKgmPKPAvECBOCHkRW2vDFQKM false sufficient binding region:351-604("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18282 uniprotkb:P34331 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462839|imex:IM-11985-707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 intact-crc:EAA3A426F7F4F4DB|rigid:3ARts6dUHCDki92StX3rvNiaubw false - sufficient binding region:337-649("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G4RT11 uniprotkb:Q03563 intact:EBI-6458195|ensemblmetazoa:B0511.9c.1|uniprotkb:A9D8E6|uniprotkb:G4RT06|uniprotkb:H2KYB5 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:cdc26_caeel(display_long)|uniprotkb:Cell division cycle protein 26 homolog(gene name synonym)|uniprotkb:mat-4(gene name synonym)|uniprotkb:tag-265(gene name synonym)|uniprotkb:B0511.9(orf name)|uniprotkb:cdc-26(gene name)|psi-mi:cdc-26(display_short) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462849|imex:IM-11985-708 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:B0511.9c.1(transcript)|ensemblmetazoa:WBGene00015235(gene)|go:"GO:0005634"(nucleus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:B0511.9a|wormbase:B0511.9b|wormbase:B0511.9d|refseq:NP_001251445.1|refseq:NP_740913.3|refseq:NP_740914.2|refseq:NP_001251447.1|wormbase:B0511.9c|dip:DIP-26086N refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:4EiUm/eby0CTOnoyalmBYdJZmOE6239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:4F041A4A808B40F1|rigid:/+WAnbTq1F9uO4mosHrE4vbUWY0 false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03563 uniprotkb:Q27488 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 intact:EBI-318271|ensemblmetazoa:D1054.2.1|ensemblmetazoa:D1054.2.2 psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:psa2_caeel(display_long)|uniprotkb:pas-2(gene name)|psi-mi:pas-2(display_short)|uniprotkb:D1054.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462859|imex:IM-11985-709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N refseq:NP_505750.1|wormbase:D1054.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR034644|reactome:R-CEL-5687128|interpro:IPR029055|reactome:R-CEL-187577|ensemblmetazoa:D1054.2.1(transcript)|ensemblmetazoa:D1054.2.2(transcript)|ensemblmetazoa:WBGene00003923(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-6798695|reactome:R-CEL-5632684|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 rogid:oxMITWZNzWRcUpGSL6T7pKrm+Xs6239 intact-crc:343F14442D0DA9CA|rigid:vnTLrbkR3BbQ0i4nqSbZCf8NzTo false sufficient binding region:336-464("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19713 uniprotkb:Q03563 intact:EBI-6458795|ensemblmetazoa:F22B5.9.1 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:syfb_caeel(display_long)|uniprotkb:fars-3(gene name)|psi-mi:fars-3(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:frs-2(gene name synonym)|uniprotkb:F22B5.9(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462869|imex:IM-11985-710 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F22B5.9.1(transcript)|ensemblmetazoa:WBGene00001498(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR040659|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|refseq:NP_495785.1|wormbase:F22B5.9|interpro:IPR041616 refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vnO3fcS4LkBf8htippBIQGUn4M06239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:0EA68FF0E87E9D90|rigid:aLq1KR+HUHh8H9QTWCkdWHVb5u8 false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20052 uniprotkb:Q03563 intact:EBI-314913|ensemblmetazoa:F35G12.9.1|ensemblmetazoa:F35G12.9.2 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:apc11_caeel(display_long)|uniprotkb:apc-11(gene name)|psi-mi:apc-11(display_short)|uniprotkb:F35G12.9(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462889|imex:IM-11985-712 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497937.1|wormbase:F35G12.9|ensemblmetazoa:F35G12.9.1(transcript)|ensemblmetazoa:F35G12.9.2(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|ensemblmetazoa:WBGene00000145(gene)|dip:DIP-24995N|reactome:R-CEL-983168 refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:11SdvWjkFNUyCv4arePb6BEXKEg6239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:AF62045620A8C9B2|rigid:BJm3UtzG1N8AJaQeEXpSeuv8KmY false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44781 uniprotkb:Q03563 intact:EBI-331944|ensemblmetazoa:F33D11.10.1 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:o44781_caeel(display_long)|uniprotkb:F33D11.10(orf name)|uniprotkb:CELE_F33D11.10(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462879|imex:IM-11985-711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491703.1|wormbase:F33D11.10|dip:DIP-27243N|ensemblmetazoa:F33D11.10.1(transcript)|ensemblmetazoa:WBGene00018007(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071048"|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0016787"(hydrolase activity) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:yl7i4pfqQXlZ+Z90Bssucpen6UQ6239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:B852D3F25B496917|rigid:FZrhb8DXsyC0xeKysgjhFFFR0Uk false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q03563 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462899|imex:IM-11985-713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:3AB47195BC4AFC9B|rigid:TsbxScgoww/kdWGlib0RgDQ1e+s false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03563 uniprotkb:Q22137 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 intact:EBI-896209|ensemblmetazoa:T04A8.7a.1 psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:q22137_caeel(display_long)|uniprotkb:T04A8.7(orf name)|uniprotkb:CELE_T04A8.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462919|imex:IM-11985-715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N refseq:NP_497961.1|wormbase:T04A8.7a|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR004193(Glycoside hydrolase, family 13, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR037439|reactome:R-CEL-3322077|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|ensemblmetazoa:T04A8.7a.1(transcript)|ensemblmetazoa:WBGene00011409(gene)|go:"GO:0003844"(1,4-alpha-glucan branching enzyme activity)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0043169"(cation binding)|go:"GO:0102752"("1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)") psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 rogid:ZZY5kRKZqp6pXWB0i9HcFZUpI3w6239 intact-crc:D9F3B55F1B7FD11D|rigid:NdbdvAucB2/v++EziVzYZCWiw1A false sufficient binding region:336-464("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22078 uniprotkb:Q03563 intact:EBI-323051|ensemblmetazoa:T01G9.4.1|ensemblmetazoa:T01G9.4.2 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:q22078_caeel(display_long)|uniprotkb:npp-2(gene name)|psi-mi:npp-2(display_short)|uniprotkb:CELE_T01G9.4(orf name)|uniprotkb:T01G9.4(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462909|imex:IM-11985-714 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492256.1|wormbase:T01G9.4|interpro:IPR011502(Nucleoporin, Nup85-like)|ensemblmetazoa:T01G9.4.1(transcript)|ensemblmetazoa:T01G9.4.2(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090435"(protein localization to nuclear envelope)|ensemblmetazoa:WBGene00003788(gene)|reactome:R-CEL-9615933 refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zeIaeaV7GOQHaMra/3zZ7xf75q46239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:4AA44444D28E21DD|rigid:09YHo+s1nGAXHp+1krGLZxcJkYg false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34563 uniprotkb:Q03563 intact:EBI-327278|ensemblmetazoa:T05G5.10a.1 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:if5a1_caeel(display_long)|uniprotkb:iff-1(gene name)|psi-mi:iff-1(display_short)|uniprotkb:T05G5.10(orf name)|uniprotkb:Initiation factor five protein 1(gene name synonym) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462929|imex:IM-11985-716 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001255021.1|refseq:NP_001255020.1|wormbase:T05G5.10a|reactome:R-CEL-204626|ensemblmetazoa:T05G5.10a.1(transcript)|ensemblmetazoa:WBGene00002064(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0007276"(gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|go:"GO:0005737"(cytoplasm)|dip:DIP-25111N refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ew1bTZgD4xTVQM92D5AvNdLqTig6239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:E6D3914D0EEB81FD|rigid:N7m0EluCsCuTxIOwPcdoQjM0HSE false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03563 uniprotkb:P91457 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462939|imex:IM-11985-717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:E328EBC6DEB87F58|rigid:MFtlj3okoZiHoqiXBo1NaNr+HxE false sufficient binding region:336-464("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFA2 uniprotkb:Q03563 intact:EBI-328435|ensemblmetazoa:T27F2.3.1 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:bir1_caeel(display_long)|uniprotkb:bir-1(gene name)|psi-mi:bir-1(display_short)|uniprotkb:Baculoviral IAP repeat-containing protein bir-1(gene name synonym)|uniprotkb:T27F2.3(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462949|imex:IM-11985-718 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q22837(uniprot-removed-ac)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|refseq:NP_505949.1|ensemblmetazoa:T27F2.3.1(transcript)|ensemblmetazoa:WBGene00000249(gene)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016573"(histone acetylation)|go:"GO:0018991"(oviposition)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030496"(midbody)|wormbase:T27F2.3|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040039"(inductive cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:UuKWa2EfGH/bNR+k86799sBFhrI6239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:FFBA8B09C421D326|rigid:VNs0Eotl2h73FXKw5YoThvqMxQQ false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECR7 uniprotkb:Q03563 intact:EBI-330567|ensemblmetazoa:Y41C4A.10.1 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:g5ecr7_caeel(display_long)|uniprotkb:3L686(gene name synonym)|uniprotkb:elb-1(gene name)|psi-mi:elb-1(display_short)|uniprotkb:Y41C4A.10(orf name)|uniprotkb:CELE_Y41C4A.10(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462959|imex:IM-11985-719 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9XWU4(uniprot-removed-ac)|refseq:NP_499517.1|reactome:R-CEL-674695|reactome:R-CEL-6796648|wormbase:Y41C4A.10|interpro:IPR039049|interpro:IPR029071|reactome:R-CEL-1234176|reactome:R-CEL-983168|reactome:R-CEL-8951664|ensemblmetazoa:WBGene00001235(gene)|ensemblmetazoa:Y41C4A.10.1(transcript)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|reactome:R-CEL-75955|reactome:R-CEL-112382 refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:nd6q1xH1t5OIdfLT3hHtTS3gTqU6239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:A342C02EFD5CF639|rigid:oe9rMg1zhKd+QQo7pXqP3CLIuWA false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03563 uniprotkb:G5ECG0 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 intact:EBI-320612|ensemblmetazoa:Y54E2A.3.1 psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:tacc1_caeel(display_long)|uniprotkb:2P40(gene name synonym)|uniprotkb:tac-1(gene name)|psi-mi:tac-1(display_short)|uniprotkb:Y54E2A.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462979|imex:IM-11985-721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N interpro:IPR007707(Transforming acidic coiled-coil-containing)|refseq:NP_497059.1|uniprotkb:Q9XWJ0(uniprot-removed-ac)|ensemblmetazoa:WBGene00006381(gene)|ensemblmetazoa:Y54E2A.3.1(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0035046"(pronuclear migration)|go:"GO:0043204"(perikaryon)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|wormbase:Y54E2A.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 rogid:acqJmi7NEO4v3zxOKwy1zH35+O86239 intact-crc:688732EC0CC47837|rigid:4nx5YbAbhlEXa+dzzFnr2gwfi7M false sufficient binding region:336-464("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03563 uniprotkb:Q95Y13 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 intact:EBI-6456240|ensemblmetazoa:Y41D4B.19a.1 psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:q95y13_caeel(display_long)|uniprotkb:Y41D4B.19(orf name)|uniprotkb:npp-8(gene name)|psi-mi:npp-8(display_short)|uniprotkb:CELE_Y41D4B.19(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462969|imex:IM-11985-720 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N ensemblmetazoa:WBGene00003794(gene)|ensemblmetazoa:Y41D4B.19a.1(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR036322|refseq:NP_500104.1|wormbase:Y41D4B.19a|dip:DIP-25737N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 rogid:bFPI3oAfEna6NRWSDNI0G+zgwUo6239 intact-crc:C17E63777B4021DB|rigid:Qa70CL6NksNu2jhkBItZOrt52Q0 false sufficient binding region:336-464("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N4A7-1 uniprotkb:Q03563 intact:EBI-6456140|ensemblmetazoa:Y77E11A.13a.1 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 psi-mi:q9n4a7-1(display_long)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:Nuclear pore complex protein 20(gene name synonym)|uniprotkb:npp-20(gene name)|psi-mi:npp-20(display_short)|uniprotkb:CeSec13R(gene name synonym)|uniprotkb:sec-13(gene name synonym)|uniprotkb:Y77E11A.13(orf name) psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462989|imex:IM-11985-722 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-318290(isoform-parent)|ensemblmetazoa:WBGene00003806(gene)|ensemblmetazoa:Y77E11A.13a.1(transcript) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZKmmnaa7DFkQzBBKNad56Ic7GvI6239 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 intact-crc:3B4EB1DA3FF4E98D|rigid:zYYnzfRjRkTjgrrzo2YT0ZJSWuw false - sufficient binding region:336-464("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03563 uniprotkb:P34605 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 intact:EBI-312149|ensemblmetazoa:ZK1098.5.1 psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:tppc3_caeel(display_long)|uniprotkb:trpp-3(gene name)|psi-mi:trpp-3(display_short)|uniprotkb:ZK1098.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6462999|imex:IM-11985-723 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N refseq:NP_499100.1|wormbase:ZK1098.5|reactome:R-CEL-204005|ensemblmetazoa:WBGene00014222(gene)|ensemblmetazoa:ZK1098.5.1(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042338"(cuticle development involved in collagen and cuticulin-based cuticle molting cycle)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|reactome:R-CEL-8876198|dip:DIP-25615N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 rogid:Nhf/6V5QuvCydW1gyu9tp4d8VQA6239 intact-crc:68FD01F1B06FD01D|rigid:qzgnfVQN0wuUCosSs6fgVxX6BjA false sufficient binding region:336-464("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18282 uniprotkb:P34331 intact:EBI-2002254|ensemblmetazoa:C28C12.2.1 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 psi-mi:q18282_caeel(display_long)|uniprotkb:mesp-1(gene name)|psi-mi:mesp-1(display_short)|uniprotkb:CELE_C28C12.2(orf name)|uniprotkb:C28C12.2(orf name) psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463009|imex:IM-11985-724 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501453.1|wormbase:C28C12.2|ensemblmetazoa:C28C12.2.1(transcript)|ensemblmetazoa:WBGene00016178(gene) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:a+I8qYsZZjttKJkVbBBZpcLSjc86239 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 intact-crc:200C518902D9CB3B|rigid:3ARts6dUHCDki92StX3rvNiaubw false - sufficient binding region:302-649("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21776 uniprotkb:P34331 intact:EBI-331300|ensemblmetazoa:R06C7.8.1 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 psi-mi:bub1_caeel(display_long)|uniprotkb:bub-1(gene name)|psi-mi:bub-1(display_short)|uniprotkb:Budding uninhibited by benzimidazole 1(gene name synonym)|uniprotkb:R06C7.8(orf name) psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463019|imex:IM-11985-725 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492051.1|wormbase:R06C7.8|dip:DIP-27465N|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensemblmetazoa:R06C7.8.1(transcript)|ensemblmetazoa:WBGene00000275(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000280"(nuclear division)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008406"(gonad development)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0051316"(attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR000719(Protein kinase, core)|reactome:R-CEL-141430 refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vCA2zo1b4B9goXwPJfQDrOZhHjY6239 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 intact-crc:65B13999200E7683|rigid:GR9lhNu8p7XV35eqcnfShm6IKHM false - sufficient binding region:302-649("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:P34331 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463029|imex:IM-11985-726 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 intact-crc:8090A48E82FD453E|rigid:qi+k2hxFjSQrDVQIJYyaBxMQDp0 false - sufficient binding region:302-649("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34331 uniprotkb:Q21776 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 intact:EBI-331300|ensemblmetazoa:R06C7.8.1 psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:bub1_caeel(display_long)|uniprotkb:bub-1(gene name)|psi-mi:bub-1(display_short)|uniprotkb:Budding uninhibited by benzimidazole 1(gene name synonym)|uniprotkb:R06C7.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463039|imex:IM-11985-727 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N refseq:NP_492051.1|wormbase:R06C7.8|dip:DIP-27465N|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensemblmetazoa:R06C7.8.1(transcript)|ensemblmetazoa:WBGene00000275(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000280"(nuclear division)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008406"(gonad development)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043515"(kinetochore binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0051257"(meiotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0051307"(meiotic chromosome separation)|go:"GO:0051316"(attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR000719(Protein kinase, core)|reactome:R-CEL-141430 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 rogid:vCA2zo1b4B9goXwPJfQDrOZhHjY6239 intact-crc:FAA1FF9CE620EFA2|rigid:GR9lhNu8p7XV35eqcnfShm6IKHM false sufficient binding region:293-649("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34331 uniprotkb:Q09601-1 intact:EBI-315211|uniprotkb:O61662|uniprotkb:O76763|ensemblmetazoa:C14B9.4b.1 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:plk1_caeel(display_long)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:Polo-like kinase 1(gene name synonym) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463049|imex:IM-11985-728 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021173.1|refseq:NP_001021174.1|wormbase:C14B9.4a|wormbase:C14B9.4b|ensemblmetazoa:C14B9.4b.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007147"(female meiosis II)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051233"(spindle midzone)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|ensemblmetazoa:WBGene00004042(gene)|dip:DIP-25456N intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:HWVMEZdDYW1jwOLLr+WwNiaZhCc6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:4F978B9E44F88310|rigid:qi+k2hxFjSQrDVQIJYyaBxMQDp0 false sufficient binding region:293-649("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03563 uniprotkb:Q8I711 intact:EBI-313306|uniprotkb:Q9XVX9|uniprotkb:Q9XVY0|ensemblmetazoa:B0464.5a.1|ensemblmetazoa:B0464.5a.2 intact:EBI-6456394|ensemblmetazoa:T10F2.1b.1 psi-mi:spk1_caeel(display_long)|uniprotkb:spk-1(gene name)|psi-mi:spk-1(display_short)|uniprotkb:rsk-1(gene name synonym)|uniprotkb:srk-1(gene name synonym)|uniprotkb:B0464.5(orf name) psi-mi:q8i711_caeel(display_long)|uniprotkb:gars-1(gene name)|psi-mi:gars-1(display_short)|uniprotkb:Glycine--tRNA ligase(gene name synonym)|uniprotkb:CELE_T10F2.1(orf name)|uniprotkb:T10F2.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463059|imex:IM-11985-729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021133.1|refseq:NP_001021134.1|refseq:NP_499080.3|wormbase:B0464.5a|wormbase:B0464.5b|wormbase:B0464.5c|ensemblmetazoa:B0464.5a.1(transcript)|ensemblmetazoa:B0464.5a.2(transcript)|ensemblmetazoa:WBGene00004980(gene)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26907N ensemblmetazoa:T10F2.1b.1(transcript)|ensemblmetazoa:WBGene00001744(gene)|go:"GO:0004820"(glycine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006426"(glycyl-tRNA aminoacylation)|go:"GO:0016740"(transferase activity)|interpro:IPR033731|interpro:IPR027031|interpro:IPR000738(WHEP-TRS)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002315(Glycyl-tRNA synthetase, alpha2 dimer)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|refseq:NP_871640.1|wormbase:T10F2.1b|interpro:IPR036621 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:XiXjIW+6GLo2OhI3NOhhgAdNoLE6239 rogid:gkHJId9s+GIJ2kCoYrSi93i34BY6239 intact-crc:1029D3D15A3AFFB1|rigid:UrWOV3eVdGlD6FRmySNBHeCE9N8 false sufficient binding region:265-464("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39055-2 uniprotkb:P39055-1 intact:EBI-317960|ensemblmetazoa:C02C6.1b.1 intact:EBI-6463069|ensemblmetazoa:C02C6.1a.1 psi-mi:p39055-2(display_long)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short)|uniprotkb:C02C6.1(orf name) psi-mi:p39055-1(display_long)|uniprotkb:C02C6.1(orf name)|uniprotkb:dyn-1(gene name)|psi-mi:dyn-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463074|imex:IM-11985-730 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-317945(dyn1_caeel)|ensemblmetazoa:C02C6.1b.1(transcript)|ensemblmetazoa:WBGene00001130(gene) intact:EBI-317945(isoform-parent)|ensemblmetazoa:C02C6.1a.1(transcript)|ensemblmetazoa:WBGene00001130(gene) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:YwrOSrDQNOkP6wqRv7xUObIjb6g6239 rogid:uqDLQ6Qxfv3NboA/DRTsUZYharA6239 intact-crc:B036F2DE6C55DAF1|rigid:pAFE23X5EInzJem9FBbdDMu75Hc false sufficient binding region:237-838("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54811 uniprotkb:P54812 intact:EBI-320245|ensemblmetazoa:C06A1.1.1 intact:EBI-320265|uniprotkb:Q18560|ensemblmetazoa:C41C4.8.1|ensemblmetazoa:C41C4.8.2 psi-mi:tera1_caeel(display_long)|uniprotkb:C06A1.1(orf name)|uniprotkb:Cell division cycle-related protein 48.1(gene name synonym)|uniprotkb:p97/CDC48 homolog 1(gene name synonym)|uniprotkb:cdc-48.1(gene name)|psi-mi:cdc-48.1(display_short) psi-mi:tera2_caeel(display_long)|uniprotkb:C41C4.8(orf name)|uniprotkb:Cell division cycle-related protein 48.2(gene name synonym)|uniprotkb:p97/CDC48 homolog 2(gene name synonym)|uniprotkb:cdc-48.2(gene name)|psi-mi:cdc-48.2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463084|imex:IM-11985-731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496273.1|wormbase:C06A1.1|ensemblmetazoa:C06A1.1.1(transcript)|ensemblmetazoa:WBGene00007352(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|dip:DIP-26650N refseq:NP_495705.1|wormbase:C41C4.8|ensemblmetazoa:C41C4.8.1(transcript)|ensemblmetazoa:C41C4.8.2(transcript)|ensemblmetazoa:WBGene00008053(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|reactome:R-CEL-3371511|reactome:R-CEL-9013407|reactome:R-CEL-110320|reactome:R-CEL-6798695|reactome:R-CEL-382556|reactome:R-CEL-532668|reactome:R-CEL-5689877|dip:DIP-26566N|reactome:R-CEL-8876725|reactome:R-CEL-5358346 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:VgGB6CuL6hJaCop1MLkdaQAjhCE6239 rogid:8orzUPvtC7n65UHKceyBId+MP0Q6239 intact-crc:D01AF5948B93F4DB|rigid:znN7+PS+lD4NnOKTHrruTV6ymy8 false - sufficient binding region:207-470("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54812 uniprotkb:P54812 intact:EBI-320265|uniprotkb:Q18560|ensemblmetazoa:C41C4.8.1|ensemblmetazoa:C41C4.8.2 intact:EBI-320265|uniprotkb:Q18560|ensemblmetazoa:C41C4.8.1|ensemblmetazoa:C41C4.8.2 psi-mi:tera2_caeel(display_long)|uniprotkb:C41C4.8(orf name)|uniprotkb:Cell division cycle-related protein 48.2(gene name synonym)|uniprotkb:p97/CDC48 homolog 2(gene name synonym)|uniprotkb:cdc-48.2(gene name)|psi-mi:cdc-48.2(display_short) psi-mi:tera2_caeel(display_long)|uniprotkb:C41C4.8(orf name)|uniprotkb:Cell division cycle-related protein 48.2(gene name synonym)|uniprotkb:p97/CDC48 homolog 2(gene name synonym)|uniprotkb:cdc-48.2(gene name)|psi-mi:cdc-48.2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463094|imex:IM-11985-732 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495705.1|wormbase:C41C4.8|ensemblmetazoa:C41C4.8.1(transcript)|ensemblmetazoa:C41C4.8.2(transcript)|ensemblmetazoa:WBGene00008053(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|reactome:R-CEL-3371511|reactome:R-CEL-9013407|reactome:R-CEL-110320|reactome:R-CEL-6798695|reactome:R-CEL-382556|reactome:R-CEL-532668|reactome:R-CEL-5689877|dip:DIP-26566N|reactome:R-CEL-8876725|reactome:R-CEL-5358346 refseq:NP_495705.1|wormbase:C41C4.8|ensemblmetazoa:C41C4.8.1(transcript)|ensemblmetazoa:C41C4.8.2(transcript)|ensemblmetazoa:WBGene00008053(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|reactome:R-CEL-3371511|reactome:R-CEL-9013407|reactome:R-CEL-110320|reactome:R-CEL-6798695|reactome:R-CEL-382556|reactome:R-CEL-532668|reactome:R-CEL-5689877|dip:DIP-26566N|reactome:R-CEL-8876725|reactome:R-CEL-5358346 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:8orzUPvtC7n65UHKceyBId+MP0Q6239 rogid:8orzUPvtC7n65UHKceyBId+MP0Q6239 intact-crc:E8467B13E6DF1BAB|rigid:wPAP/JLmQ2OoG4b96LQH8P35RB0 false sufficient binding region:202-470("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44548 uniprotkb:P34331-2 intact:EBI-2002279|ensemblmetazoa:K06A5.4.1 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 psi-mi:knl2_caeel(display_long)|uniprotkb:knl-2(gene name)|psi-mi:knl-2(display_short)|uniprotkb:K06A5.4(orf name) psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463104|imex:IM-11985-733 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015216(SANT associated)|refseq:NP_491858.1|wormbase:K06A5.4|interpro:IPR044895|rcsb pdb:2M3A|interpro:IPR039110|ensemblmetazoa:K06A5.4.1(transcript)|ensemblmetazoa:WBGene00019432(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:75DxENUtFsHh+zV4+If5DTMKOjI6239 rogid:u830S0jdkV753ilx7DbxmhPocv86239 intact-crc:BD118BC84783DD88|rigid:3TY6jwHThQISIXY2XZ2O+BMs1fQ false sufficient binding region:1-876("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601-1 uniprotkb:Q09601 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 intact:EBI-2004755|uniprotkb:O62340|ensemblmetazoa:R06F6.5b.1 psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:nup35_caeel(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463124|imex:IM-11985-735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) interpro:IPR017389(Nucleoporin, NUP53)|refseq:NP_496324.1|refseq:NP_496325.1|wormbase:R06F6.5a|wormbase:R06F6.5b|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:C535F9997723A956|rigid:dZCFueXcCHuxuJ0mDGvkK8BXXTU false - sufficient binding region:151-301("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44548 uniprotkb:P34470 intact:EBI-2002279|ensemblmetazoa:K06A5.4.1 intact:EBI-331027|ensemblmetazoa:F58A4.3.1 psi-mi:knl2_caeel(display_long)|uniprotkb:knl-2(gene name)|psi-mi:knl-2(display_short)|uniprotkb:K06A5.4(orf name) psi-mi:hcp3_caeel(display_long)|uniprotkb:hcp-3(gene name)|psi-mi:hcp-3(display_short)|uniprotkb:F58A4.3(orf name)|uniprotkb:Holocentric chromosome-binding protein 3(gene name synonym)|uniprotkb:CENP-A homolog(gene name synonym)|uniprotkb:CeCENP-A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463114|imex:IM-11985-734 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR015216(SANT associated)|refseq:NP_491858.1|wormbase:K06A5.4|interpro:IPR044895|rcsb pdb:2M3A|interpro:IPR039110|ensemblmetazoa:K06A5.4.1(transcript)|ensemblmetazoa:WBGene00019432(gene)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) refseq:NP_499128.1|wormbase:F58A4.3|dip:DIP-27043N|ensemblmetazoa:F58A4.3.1(transcript)|ensemblmetazoa:WBGene00001831(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070199"(establishment of protein localization to chromosome)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098813"(nuclear chromosome segregation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|go:"GO:0046603"(negative regulation of mitotic centrosome separation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:75DxENUtFsHh+zV4+If5DTMKOjI6239 rogid:s6leDsHmucRjGMcKCxqMqah1h4Q6239 intact-crc:953E904B55D0797B|rigid:FAHlXn7wLnM+ktzhe0mb8GpjtJY false sufficient binding region:1-876("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09601 uniprotkb:Q9BKT9 intact:EBI-2004755|uniprotkb:O62340|ensemblmetazoa:R06F6.5b.1 intact:EBI-2005827|ensemblmetazoa:Y37E3.15a.1 psi-mi:nup35_caeel(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name) psi-mi:q9bkt9_caeel(display_long)|uniprotkb:npp-13(gene name)|psi-mi:npp-13(display_short)|uniprotkb:CELE_Y37E3.15(orf name)|uniprotkb:Y37E3.15(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463134|imex:IM-11985-736 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017389(Nucleoporin, NUP53)|refseq:NP_496324.1|refseq:NP_496325.1|wormbase:R06F6.5a|wormbase:R06F6.5b|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division) interpro:IPR007231(Nucleoporin interacting component)|refseq:NP_740802.1|wormbase:Y37E3.15a|ensemblmetazoa:WBGene00003799(gene)|ensemblmetazoa:Y37E3.15a.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005643"(nuclear pore)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1903379"(regulation of mitotic chromosome condensation)|go:"GO:1990893"(mitotic chromosome centromere condensation) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 rogid:KQxxaQPFCk9tycEeORD/MJg0krY6239 intact-crc:2F2F4CCB81FCAFED|rigid:7MMNbpGZ6Ty6MmGFRKsH9tAHOKc false sufficient binding region:151-301("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17139 intact:EBI-6456340 intact:EBI-319671|uniprotkb:Q6LAD0|ensemblmetazoa:K04H4.1a.1 intact:EBI-6306333 psi-mi:co4a1_caeel(display_long)|uniprotkb:emb-9(gene name)|psi-mi:emb-9(display_short)|uniprotkb:clb-2(gene name synonym)|uniprotkb:K04H4.1(orf name) psi-mi:ebi6306333(display_short)|psi-mi:EBI-6456340(display_long)|intact:B0250.7(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463144|imex:IM-11985-737 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|refseq:NP_001022663.1|wormbase:K04H4.1a|wormbase:K04H4.1b|refseq:NP_001022662.2|ensemblmetazoa:K04H4.1a.1(transcript)|ensemblmetazoa:WBGene00001263(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR036954 - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PAygwwh1z4+A+1x0KmF3LiN6qKw6239 - intact-crc:184E893AA034E69C false sufficient binding region:1299-1759("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:P17139 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-319671|uniprotkb:Q6LAD0|ensemblmetazoa:K04H4.1a.1 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:co4a1_caeel(display_long)|uniprotkb:emb-9(gene name)|psi-mi:emb-9(display_short)|uniprotkb:clb-2(gene name synonym)|uniprotkb:K04H4.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463154|imex:IM-11985-738 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|refseq:NP_001022663.1|wormbase:K04H4.1a|wormbase:K04H4.1b|refseq:NP_001022662.2|ensemblmetazoa:K04H4.1a.1(transcript)|ensemblmetazoa:WBGene00001263(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR036954 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:PAygwwh1z4+A+1x0KmF3LiN6qKw6239 intact-crc:57802441A3DB94E4|rigid:yUccmOdVsUEDOc1BvkMVH5mQjgg false - sufficient binding region:1299-1759("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17139 uniprotkb:Q09436 intact:EBI-319671|uniprotkb:Q6LAD0|ensemblmetazoa:K04H4.1a.1 intact:EBI-300562|ensemblmetazoa:AH6.5.1 psi-mi:co4a1_caeel(display_long)|uniprotkb:emb-9(gene name)|psi-mi:emb-9(display_short)|uniprotkb:clb-2(gene name synonym)|uniprotkb:K04H4.1(orf name) psi-mi:mex6_caeel(display_long)|uniprotkb:mex-6(gene name)|psi-mi:mex-6(display_short)|uniprotkb:AH6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463164|imex:IM-11985-739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|refseq:NP_001022663.1|wormbase:K04H4.1a|wormbase:K04H4.1b|refseq:NP_001022662.2|ensemblmetazoa:K04H4.1a.1(transcript)|ensemblmetazoa:WBGene00001263(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007517"(muscle organ development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050714"(positive regulation of protein secretion)|interpro:IPR036954 ensemblmetazoa:AH6.5.1(transcript)|ensemblmetazoa:WBGene00003231(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0005829"(cytosol)|refseq:NP_496043.1|wormbase:AH6.5|reactome:R-CEL-450385|dip:DIP-26165N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PAygwwh1z4+A+1x0KmF3LiN6qKw6239 rogid:oVKWJRS2uVN3eOW+qihqknx3WJM6239 intact-crc:E3AB9A3497B2C46A|rigid:NwoyfftcD/Fpo8dAKeziBpPluDc false sufficient binding region:1251-1759("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18255 uniprotkb:Q18343 intact:EBI-314520|ensemblmetazoa:C27D9.1.1 intact:EBI-2007242|ensemblmetazoa:C31H1.8a.1 psi-mi:q18255_caeel(display_long)|uniprotkb:C27D9.1(orf name)|uniprotkb:CELE_C27D9.1(orf name) psi-mi:q18343_caeel(display_long)|uniprotkb:oops-1(gene name)|psi-mi:oops-1(display_short)|uniprotkb:C31H1.8(orf name)|uniprotkb:CELE_C31H1.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463174|imex:IM-11985-740 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009497(Protein of unknown function DUF1114)|wormbase:C27D9.1|refseq:NP_494851.2|ensemblmetazoa:C27D9.1.1(transcript)|ensemblmetazoa:WBGene00016163(gene)|go:"GO:0006486"(protein glycosylation)|go:"GO:0016020"(membrane)|go:"GO:0036065"(fucosylation)|go:"GO:0046920"("alpha-(1->3)-fucosyltransferase activity")|interpro:IPR001503(Glycosyl transferase, family 10)|reactome:R-CEL-9037629|reactome:R-CEL-975578 refseq:NP_500868.2|wormbase:C31H1.8a|ensemblmetazoa:C31H1.8a.1(transcript)|ensemblmetazoa:WBGene00016291(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:2CAJcTLTMmwKH9AtJ6AH8xQxGK06239 rogid:LE3g2wd8l7cqjuuDRueOhyIqJVU6239 intact-crc:BF3A36BA86A8EC21|rigid:GweougT0TZN/j2leAecRwSGJ6Pc false - sufficient binding region:1-104("MI:0442") - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18343 uniprotkb:G5EGT6 intact:EBI-2007242|ensemblmetazoa:C31H1.8a.1 intact:EBI-323609|ensemblmetazoa:H02I12.8.1 psi-mi:q18343_caeel(display_long)|uniprotkb:oops-1(gene name)|psi-mi:oops-1(display_short)|uniprotkb:C31H1.8(orf name)|uniprotkb:CELE_C31H1.8(orf name) psi-mi:g5egt6_caeel(display_long)|uniprotkb:cyp-31a2(gene name)|psi-mi:cyp-31a2(display_short)|uniprotkb:cyp-31A2(gene name synonym)|uniprotkb:H02I12.8(orf name)|uniprotkb:CELE_H02I12.8(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463184|imex:IM-11985-741 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500868.2|wormbase:C31H1.8a|ensemblmetazoa:C31H1.8a.1(transcript)|ensemblmetazoa:WBGene00016291(gene) wormbase:H02I12.8|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|refseq:NP_502152.3|uniprotkb:O45605(uniprot-removed-ac)|ensemblmetazoa:H02I12.8.1(transcript)|ensemblmetazoa:WBGene00010354(gene)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0020037"(heme binding)|go:"GO:0030703"(eggshell formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0048598"(embryonic morphogenesis)|interpro:IPR036396|reactome:R-CEL-193144|reactome:R-CEL-196791|reactome:R-CEL-211916|reactome:R-CEL-211976|reactome:R-CEL-211935|reactome:R-CEL-211958|reactome:R-CEL-211979|reactome:R-CEL-2142691|reactome:R-CEL-2142816 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LE3g2wd8l7cqjuuDRueOhyIqJVU6239 rogid:rFBca9MqzVl/AAexNGFIAdU82t06239 intact-crc:F5D2A16BBE18CFFE|rigid:UZOQcqmZACCfRc2U/ro7Uro4NaI false sufficient binding region:1-104("MI:0442") - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q23079 uniprotkb:Q09436 intact:EBI-2001836|ensemblmetazoa:ZC317.7.1 intact:EBI-300562|ensemblmetazoa:AH6.5.1 psi-mi:q23079_caeel(display_long)|uniprotkb:ZC317.7(orf name)|uniprotkb:CELE_ZC317.7(orf name) psi-mi:mex6_caeel(display_long)|uniprotkb:mex-6(gene name)|psi-mi:mex-6(display_short)|uniprotkb:AH6.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463194|imex:IM-11985-742 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504446.1|wormbase:ZC317.7|ensemblmetazoa:WBGene00022590(gene)|ensemblmetazoa:ZC317.7.1(transcript) ensemblmetazoa:AH6.5.1(transcript)|ensemblmetazoa:WBGene00003231(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0005829"(cytosol)|refseq:NP_496043.1|wormbase:AH6.5|reactome:R-CEL-450385|dip:DIP-26165N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vpVQ9FrBu00KCYDD4uwENT2pHm86239 rogid:oVKWJRS2uVN3eOW+qihqknx3WJM6239 intact-crc:A98E0B34E59101DF|rigid:PQ97U9XpTYB6DFeYcMJrDUQ5MP0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01488 uniprotkb:Q22866-2 intact:EBI-320537|ensemblmetazoa:C13F10.2.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:o01488_caeel(display_long)|uniprotkb:kxd-1(gene name)|psi-mi:kxd-1(display_short)|uniprotkb:C13F10.2(orf name)|uniprotkb:CELE_C13F10.2(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463215|imex:IM-11985-745 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504831.1|wormbase:C13F10.2|ensemblmetazoa:C13F10.2.1(transcript)|ensemblmetazoa:WBGene00015742(gene)|go:"GO:0032418"(lysosome localization)|go:"GO:0099078"(BORC complex)|interpro:IPR019371|interpro:IPR039843|dip:DIP-27148N intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZX/rck9tSHblPGJKegKAjZiqxeA6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:F8D1DD61D2798D18|rigid:RIxkheldf0Fs2lnj9f+sxEmkAXY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34604 uniprotkb:Q17868 intact:EBI-313831|ensemblmetazoa:ZK1098.4.1 intact:EBI-314859|ensemblmetazoa:C09G4.3.1 psi-mi:ei2ba_caeel(display_long)|uniprotkb:ZK1098.4(orf name)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym) psi-mi:cks1_caeel(display_long)|uniprotkb:cks-1(gene name)|psi-mi:cks-1(display_short)|uniprotkb:dom-6(gene name synonym)|uniprotkb:C09G4.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463208|imex:IM-11985-744 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72731|refseq:NP_499106.1|wormbase:ZK1098.4|ensemblmetazoa:WBGene00014221(gene)|ensemblmetazoa:ZK1098.4.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|dip:DIP-26550N refseq:NP_501457.1|wormbase:C09G4.3|ensemblmetazoa:C09G4.3.1(transcript)|ensemblmetazoa:WBGene00001051(gene)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR000789(Cyclin-dependent kinase, regulatory subunit)|interpro:IPR036858|dip:DIP-25964N|reactome:R-CEL-69231|reactome:R-CEL-187577 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:1RBLZL4hmLKImQHEq4lbR3UkrGo6239 rogid:OlpJM8zMwCqm6eB6A34tlx7WkrI6239 intact-crc:3DF5F6FF5D63A62F|rigid:54Ly2X2KA8SMw0iZnQQ+t6FGbVk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:H2KZL1 uniprotkb:O76258 intact:EBI-2002184|ensemblmetazoa:W04B5.3c.1 intact:EBI-2002148|ensemblmetazoa:C09G12.9.1 psi-mi:h2kzl1_caeel(display_long)|uniprotkb:W04B5.3(orf name)|uniprotkb:CELE_W04B5.3(orf name) psi-mi:o76258_caeel(display_long)|uniprotkb:tsg-101(gene name)|psi-mi:tsg-101(display_short)|uniprotkb:CELE_C09G12.9(orf name)|uniprotkb:C09G12.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463201|imex:IM-11985-743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8ITW2(uniprot-removed-ac)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_497552.2|wormbase:W04B5.3c|ensemblmetazoa:W04B5.3c.1(transcript)|ensemblmetazoa:WBGene00021020(gene)|go:"GO:0030246"(carbohydrate binding) refseq:NP_500364.2|wormbase:C09G12.9|interpro:IPR017916|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR008883(Tumour susceptibility gene 101)|reactome:R-CEL-917729|interpro:IPR037202|ensemblmetazoa:C09G12.9.1(transcript)|ensemblmetazoa:WBGene00015658(gene)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mUOkWCRr76zuZkFfM0qNLIpfx3k6239 rogid:tAhzbKmVoJZA+IwR6RLdGgDFIYI6239 intact-crc:353A6FF0B9EAA96F|rigid:MTIfrJxasOw2WWsJUfy3iqGtpKw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34331-2 uniprotkb:Q8WTJ8 intact:EBI-6456446|ensemblmetazoa:C14B9.4a.1 intact:EBI-321112|ensemblmetazoa:Y51F10.2a.1|ensemblmetazoa:Y51F10.2a.2 psi-mi:p34331-2(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:plc1(gene name synonym)|uniprotkb:C14B9.4(orf name)|uniprotkb:plk-1(gene name)|psi-mi:plk-1(display_short) psi-mi:q8wtj8_caeel(display_long)|uniprotkb:Y51F10.2(orf name)|uniprotkb:CELE_Y51F10.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463222|imex:IM-11985-746 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-315211(isoform-parent)|ensemblmetazoa:C14B9.4a.1(transcript)|ensemblmetazoa:WBGene00004042(gene) refseq:NP_740796.1|ensemblmetazoa:WBGene00021763(gene)|ensemblmetazoa:Y51F10.2a.1(transcript)|ensemblmetazoa:Y51F10.2a.2(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|wormbase:Y51F10.2a|dip:DIP-26335N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:u830S0jdkV753ilx7DbxmhPocv86239 rogid:ecYf0rK4DGesDNxewp2Vg2bxK/Y6239 intact-crc:8B1AE7EDA98B2B62|rigid:InGp+2tws8IxbRu8rcUck+4nnf4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93233 uniprotkb:Q22866-2 intact:EBI-313525|ensemblmetazoa:C17E4.5.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:q93233_caeel(display_long)|uniprotkb:pabp-2(gene name)|psi-mi:pabp-2(display_short)|uniprotkb:CELE_C17E4.5(orf name)|uniprotkb:C17E4.5(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463229|imex:IM-11985-747 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72163|reactome:R-CEL-72187|reactome:R-CEL-77595|refseq:NP_492504.1|wormbase:C17E4.5|ensemblmetazoa:C17E4.5.1(transcript)|ensemblmetazoa:WBGene00003904(gene)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|dip:DIP-26233N|reactome:R-CEL-73856 intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:UQ8eYmFDtdGomnt6MTsw6TJaLno6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:97170E82880F8BF2|rigid:WkV0frdlBWXBMtHeZ9yd4QyIo2o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O02327 uniprotkb:P48152 intact:EBI-315894|ensemblmetazoa:T23D8.3.1|ensemblmetazoa:T23D8.3.2 intact:EBI-313865|ensemblmetazoa:C23G10.3.1 psi-mi:ltv1_caeel(display_long)|uniprotkb:T23D8.3(orf name) psi-mi:rs3_caeel(display_long)|uniprotkb:rps-3(gene name)|psi-mi:rps-3(display_short)|uniprotkb:C23G10.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463236|imex:IM-11985-748 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492637.1|wormbase:T23D8.3|ensemblmetazoa:T23D8.3.1(transcript)|ensemblmetazoa:T23D8.3.2(transcript)|ensemblmetazoa:WBGene00011944(gene)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR007307(Low temperature viability protein)|go:"GO:0042274"(ribosomal small subunit biogenesis)|dip:DIP-25511N refseq:NP_498349.1|wormbase:C23G10.3|reactome:R-CEL-72706|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975957|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR018280|interpro:IPR036419|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|ensemblmetazoa:C23G10.3.1(transcript)|ensemblmetazoa:WBGene00004472(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|reactome:R-CEL-72649|reactome:R-CEL-975956|dip:DIP-25651N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:kymVaYLS75jAN3UD3cMIltm4qGI6239 rogid:f2O4JkLD1Cmfy3us3irJy9wi5tA6239 intact-crc:6AB3A89CB1EED815|rigid:7U7UtIIKSuwSR9Ch4Mq/GtdRX/g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17607 uniprotkb:Q9GZH2 intact:EBI-316213|ensemblmetazoa:C27H6.2.1 intact:EBI-316221|ensemblmetazoa:T22D1.10.1|ensemblmetazoa:T22D1.10.2 psi-mi:ruvb1_caeel(display_long)|uniprotkb:ruvb-1(gene name)|psi-mi:ruvb-1(display_short)|uniprotkb:Pontin(gene name synonym)|uniprotkb:C27H6.2(orf name) psi-mi:ruvb2_caeel(display_long)|uniprotkb:ruvb-2(gene name)|psi-mi:ruvb-2(display_short)|uniprotkb:Reptin(gene name synonym)|uniprotkb:T22D1.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463243|imex:IM-11985-749 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505567.2|reactome:R-CEL-5689880|wormbase:C27H6.2|ensemblmetazoa:C27H6.2.1(transcript)|ensemblmetazoa:WBGene00007784(gene)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0002119"(nematode larval development)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|dip:DIP-25966N interpro:IPR027417|refseq:NP_501067.1|wormbase:T22D1.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR042487|interpro:IPR037942|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027238|ensemblmetazoa:T22D1.10.1(transcript)|ensemblmetazoa:T22D1.10.2(transcript)|ensemblmetazoa:WBGene00020687(gene)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR041048 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ClLKmYAiHB+gCDwvg9vaeL2MIxc6239 rogid:dn+URkAlY1J22vwLn+hGlRujVis6239 intact-crc:8E4A786CE5F40310|rigid:q2/j9hQlHGogX9f025f1TaA8qQk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95005 uniprotkb:Q22866-2 intact:EBI-316796|ensemblmetazoa:C36B1.4.1|ensemblmetazoa:C36B1.4.2 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:psa7_caeel(display_long)|uniprotkb:pas-4(gene name)|psi-mi:pas-4(display_short)|uniprotkb:C36B1.4(orf name)|uniprotkb:Proteasome subunit alpha 4(gene name synonym) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463264|imex:IM-11985-752 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-5689603|reactome:R-CEL-5689880|refseq:NP_492360.1|wormbase:C36B1.4|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:C36B1.4.1(transcript)|ensemblmetazoa:C36B1.4.2(transcript)|ensemblmetazoa:WBGene00003925(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|reactome:R-CEL-68949|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:WWXt5jeuKRCX9WomT3Wqk45PRIc6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:6F0A160B0D861C0E|rigid:3IiI+VkQeot4oknB+0RojO2xwjA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95017 uniprotkb:P34342-1 intact:EBI-328938|uniprotkb:Q9GYI5|ensemblmetazoa:F29B9.6.2|ensemblmetazoa:F29B9.6.1 intact:EBI-6456879|ensemblmetazoa:C29E4.3a.1 psi-mi:ubc9_caeel(display_long)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)|uniprotkb:ubc-9(gene name)|psi-mi:ubc-9(display_short)|uniprotkb:F29B9.6(orf name)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 9(gene name synonym)|uniprotkb:Ubiquitin-protein ligase 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym) psi-mi:p34342-1(display_long)|uniprotkb:RanGAP(gene name synonym)|uniprotkb:C29E4.3(orf name)|uniprotkb:Ran nuclear import/export-related protein 2(gene name synonym)|uniprotkb:ran-2(gene name)|psi-mi:ran-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463257|imex:IM-11985-751 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001023158.1|wormbase:F29B9.6|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-3065678|reactome:R-CEL-3108214|reactome:R-CEL-3899300|reactome:R-CEL-8866904|reactome:R-CEL-5696395|dip:DIP-25778N|reactome:R-CEL-4551638|ensemblmetazoa:F29B9.6.2(transcript)|ensemblmetazoa:WBGene00006706(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0032093"(SAM domain binding)|ensemblmetazoa:F29B9.6.1(transcript)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:1903827"|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|go:"GO:0043282"(pharyngeal muscle development)|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 ensemblmetazoa:C29E4.3a.1(transcript)|ensemblmetazoa:WBGene00004303(gene)|intact:EBI-6499769(isoform-parent) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gtx9n8+8h+7G2tVUkUZ3Kkp6/fA6239 rogid:1uQylfSmaggjWNAEbOKcvb6nj/c6239 intact-crc:D5C2B58F36604461|rigid:MA33XwZYve+OhY35AiWs4Ohhf+8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6460247 uniprotkb:Q09248 intact:EBI-6306345 intact:EBI-316282|ensemblmetazoa:C28H8.12.1|ensemblmetazoa:C28H8.12.2 psi-mi:ebi6306345(display_short)|psi-mi:EBI-6460247(display_long)|intact:C17E4.2(author assigned name) psi-mi:dctn2_caeel(display_long)|uniprotkb:C28H8.12(orf name)|uniprotkb:dnc-2(gene name)|psi-mi:dnc-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463250|imex:IM-11985-750 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_498286.1|wormbase:C28H8.12|reactome:R-CEL-6811436|ensemblmetazoa:C28H8.12.1(transcript)|ensemblmetazoa:C28H8.12.2(transcript)|ensemblmetazoa:WBGene00001018(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005869"(dynactin complex)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007097"(nuclear migration)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0035046"(pronuclear migration)|go:"GO:0035047"(centrosomal and pronuclear rotation)|interpro:IPR028133|dip:DIP-25501N|reactome:R-CEL-6807878|reactome:R-CEL-3371497 psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:St08rjUoNsp4YpefpjkuPLCjgU46239 intact-crc:7A48C3C362BC093D false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:O01501-1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-6457824|ensemblmetazoa:C37A2.4a.1 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:o01501-1(display_long)|uniprotkb:C37A2.4(orf name)|uniprotkb:cye-1(gene name)|psi-mi:cye-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463278|imex:IM-11985-754 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) ensemblmetazoa:C37A2.4a.1(transcript)|ensemblmetazoa:WBGene00000871(gene)|intact:EBI-6499833(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:THl5Hcv1lfLuT3xEXRZhEQm1+886239 intact-crc:823F5B4976D505EB|rigid:Q4O/LpKWtzmrJuUPFF1fPy2KI6g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22198 uniprotkb:O01501-1 intact:EBI-2002710|ensemblmetazoa:T05A6.2a.1|ensemblmetazoa:T05A6.2a.2 intact:EBI-6457824|ensemblmetazoa:C37A2.4a.1 psi-mi:q22198_caeel(display_long)|uniprotkb:cki-2(gene name)|psi-mi:cki-2(display_short)|uniprotkb:CELE_T05A6.2(orf name)|uniprotkb:T05A6.2(orf name) psi-mi:o01501-1(display_long)|uniprotkb:C37A2.4(orf name)|uniprotkb:cye-1(gene name)|psi-mi:cye-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463271|imex:IM-11985-753 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003175(Cyclin-dependent kinase inhibitor)|refseq:NP_495642.3|wormbase:T05A6.2a|ensemblmetazoa:T05A6.2a.1(transcript)|ensemblmetazoa:T05A6.2a.2(transcript)|ensemblmetazoa:WBGene00000517(gene)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008406"(gonad development)|go:"GO:0032875"(regulation of DNA endoreduplication)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition) ensemblmetazoa:C37A2.4a.1(transcript)|ensemblmetazoa:WBGene00000871(gene)|intact:EBI-6499833(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:jW1+H17UZr7t4c4gAGcK3tOk8WE6239 rogid:THl5Hcv1lfLuT3xEXRZhEQm1+886239 intact-crc:D6580CECFDC10BBA|rigid:pMSH7f8WVRumVtpntCwowK7PMGc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GRY9 uniprotkb:O01501-1 intact:EBI-320508|ensemblmetazoa:Y59A8B.10a.1|ensemblmetazoa:Y59A8B.10a.2|ensemblmetazoa:Y59A8B.10a.3 intact:EBI-6457824|ensemblmetazoa:C37A2.4a.1 psi-mi:q9gry9_caeel(display_long)|uniprotkb:nova-1(gene name)|psi-mi:nova-1(display_short)|uniprotkb:CELE_Y59A8B.10(orf name)|uniprotkb:Y59A8B.10(orf name) psi-mi:o01501-1(display_long)|uniprotkb:C37A2.4(orf name)|uniprotkb:cye-1(gene name)|psi-mi:cye-1(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463285|imex:IM-11985-755 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y59A8B.10a|ensemblmetazoa:WBGene00013347(gene)|ensemblmetazoa:Y59A8B.10a.1(transcript)|ensemblmetazoa:Y59A8B.10a.2(transcript)|ensemblmetazoa:Y59A8B.10a.3(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|refseq:NP_001256769.1|dip:DIP-24651N ensemblmetazoa:C37A2.4a.1(transcript)|ensemblmetazoa:WBGene00000871(gene)|intact:EBI-6499833(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gInq7hxk90pbcpjxNwzmjqwdm+U6239 rogid:THl5Hcv1lfLuT3xEXRZhEQm1+886239 intact-crc:FC07B0C325F6C629|rigid:XUJMHmOAsg+GAfJRfslpgi7HYx8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDS1 uniprotkb:Q18508 intact:EBI-319610|ensemblmetazoa:F14F3.1a.1|intact:EBI-2002749|uniprotkb:G5EE71|uniprotkb:Q17356|uniprotkb:Q95ZV2 intact:EBI-2002730|ensemblmetazoa:C38D4.3.1 psi-mi:vab3_caeel(display_long)|uniprotkb:vab-3(gene name)|psi-mi:vab-3(display_short)|uniprotkb:Homeobox and paired domain-containing protein vab-3(gene name synonym)|uniprotkb:Protein male abnormal 18(gene name synonym)|uniprotkb:Variable abnormal morphology protein 3(gene name synonym)|uniprotkb:mab-18(gene name synonym)|uniprotkb:pax-6(gene name synonym)|uniprotkb:F14F3.1(orf name) psi-mi:mel28_caeel(display_long)|uniprotkb:mel-28(gene name)|psi-mi:mel-28(display_short)|uniprotkb:Maternal effect lethal protein 28(gene name synonym)|uniprotkb:C38D4.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463292|imex:IM-11985-756 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q17359(uniprot-removed-ac)|ensemblmetazoa:F14F3.1a.1(transcript)|ensemblmetazoa:WBGene00006870(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1903355"(negative regulation of distal tip cell migration)|interpro:IPR043182|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|refseq:NP_001024570.1|wormbase:F14F3.1a|refseq:NP_001024571.1|refseq:NP_001024572.1|interpro:IPR036388|reactome:R-CEL-8939245|interpro:IPR043565|wormbase:F14F3.1b|wormbase:F14F3.1c refseq:NP_497987.2|wormbase:C38D4.3|ensemblmetazoa:C38D4.3.1(transcript)|ensemblmetazoa:WBGene00003210(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060090"(molecular adaptor activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2020/12/11 rogid:u0yCuWg3AVikrPpUISTYa48NK7k6239 rogid:UEMa5/rs0WbLvnqlwj+dYCYc6qI6239 intact-crc:990139A7783A3136|rigid:smohH2q4IDHiyknPQ/MNfS7f7j0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17666 uniprotkb:P10986 intact:EBI-317257|ensemblmetazoa:C45G3.1.1 intact:EBI-321916|uniprotkb:Q7YSY2|ensemblmetazoa:M03F4.2a.1 psi-mi:o17666_caeel(display_long)|uniprotkb:aspm-1(gene name)|psi-mi:aspm-1(display_short)|uniprotkb:C45G3.1(orf name)|uniprotkb:CELE_C45G3.1(orf name) psi-mi:act4_caeel(display_long)|uniprotkb:act-4(gene name)|psi-mi:act-4(display_short)|uniprotkb:M03F4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463299|imex:IM-11985-757 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492467.1|wormbase:C45G3.1|ensemblmetazoa:C45G3.1.1(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|ensemblmetazoa:WBGene00008107(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0051233"(spindle midzone)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051296"(establishment of meiotic spindle orientation)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|dip:DIP-24587N refseq:NP_508841.1|wormbase:M03F4.2a|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|ensemblmetazoa:M03F4.2a.1(transcript)|ensemblmetazoa:WBGene00000066(gene)|go:"GO:0000281"(mitotic cytokinesis)|dip:DIP-27204N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:3HsZ5W1fxEraEGP5zR4dmX+8mo06239 rogid:zehthX6Qo/gSO5k1j5Epcffr8Sc6239 intact-crc:038A50F331A64715|rigid:J6U+TZJzpbN3wv/88yysVxjFuk8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17666 uniprotkb:Q22866-2 intact:EBI-317257|ensemblmetazoa:C45G3.1.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:o17666_caeel(display_long)|uniprotkb:aspm-1(gene name)|psi-mi:aspm-1(display_short)|uniprotkb:C45G3.1(orf name)|uniprotkb:CELE_C45G3.1(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463306|imex:IM-11985-758 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492467.1|wormbase:C45G3.1|ensemblmetazoa:C45G3.1.1(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|ensemblmetazoa:WBGene00008107(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0051233"(spindle midzone)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051296"(establishment of meiotic spindle orientation)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|dip:DIP-24587N intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:3HsZ5W1fxEraEGP5zR4dmX+8mo06239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:10AB950478DEEF3B|rigid:K/vdpnJ37liF8wJQWA2znZibgrg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22936 uniprotkb:P91175 intact:EBI-316827|ensemblmetazoa:C50E3.13.1 intact:EBI-2415020|ensemblmetazoa:C50F2.3.1 psi-mi:q22936_caeel(display_long)|uniprotkb:C50E3.13(orf name)|uniprotkb:CELE_C50E3.13(orf name) psi-mi:p91175_caeel(display_long)|uniprotkb:syf-1(gene name)|psi-mi:syf-1(display_short)|uniprotkb:C50F2.3(orf name)|uniprotkb:CELE_C50F2.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463313|imex:IM-11985-759 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_504969.1|wormbase:C50E3.13|ensemblmetazoa:C50E3.13.1(transcript)|ensemblmetazoa:WBGene00016824(gene)|dip:DIP-27325N refseq:NP_491250.1|wormbase:C50F2.3|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-CEL-6781823|reactome:R-CEL-6782135|reactome:R-CEL-6782210|reactome:R-CEL-72163|ensemblmetazoa:C50F2.3.1(transcript)|ensemblmetazoa:WBGene00016837(gene)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:MiUSA8BPrCirSbVAwI+lRiUOkAY6239 rogid:TJCW0aRExDbLbOr1D0eUTR8CTO86239 intact-crc:4787125D370A92ED|rigid:y45TbprWBSEfYztmWlAfhdUeJxE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EFA9 intact:EBI-6463320 intact:EBI-6457394|ensemblmetazoa:C52D10.7.1 intact:EBI-6306355 psi-mi:g5efa9_caeel(display_long)|uniprotkb:C52D10.7(orf name)|uniprotkb:skr-9(gene name)|psi-mi:skr-9(display_short)|uniprotkb:CELE_C52D10.7(orf name) psi-mi:ebi6306355(display_short)|psi-mi:EBI-6463320(display_long)|intact:F22E5.17(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463324|imex:IM-11985-760 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:C52D10.7.1(transcript)|ensemblmetazoa:WBGene00004815(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_503043.1|wormbase:C52D10.7|interpro:IPR036296 - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:TCdjs4T6zXW+/6oX4z3lFH4hBKQ6239 - intact-crc:6884A3D48A7A2A5A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N5V3 uniprotkb:Q19749 intact:EBI-320898|ensemblmetazoa:C53D5.6.1 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 psi-mi:q9n5v3_caeel(display_long)|uniprotkb:imb-3(gene name)|psi-mi:imb-3(display_short)|uniprotkb:CELE_C53D5.6(orf name)|uniprotkb:C53D5.6(orf name) psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463331|imex:IM-11985-761 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490715.1|wormbase:C53D5.6|ensemblmetazoa:C53D5.6.1(transcript)|ensemblmetazoa:WBGene00002077(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|interpro:IPR041389|interpro:IPR041653|dip:DIP-26917N refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+DZB8n7UfeEeXcLYSkOaYJ0YUNI6239 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 intact-crc:1544866119184C22|rigid:DQ8oMpyC522PaEWe0EbtvGNLMYA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34604 uniprotkb:O44156 intact:EBI-313831|ensemblmetazoa:ZK1098.4.1 intact:EBI-318264|ensemblmetazoa:CD4.6.1 psi-mi:ei2ba_caeel(display_long)|uniprotkb:ZK1098.4(orf name)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym) psi-mi:psa1_caeel(display_long)|uniprotkb:pas-6(gene name)|psi-mi:pas-6(display_short)|uniprotkb:CD4.6(orf name)|uniprotkb:Proteasome subunit alpha 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463338|imex:IM-11985-762 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72731|refseq:NP_499106.1|wormbase:ZK1098.4|ensemblmetazoa:WBGene00014221(gene)|ensemblmetazoa:ZK1098.4.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|dip:DIP-26550N refseq:NP_504472.1|wormbase:CD4.6|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR029055|reactome:R-CEL-187577|reactome:R-CEL-5687128|ensemblmetazoa:CD4.6.1(transcript)|ensemblmetazoa:WBGene00003927(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-8932339|reactome:R-CEL-5632684|reactome:R-CEL-68949|interpro:IPR035144|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:1RBLZL4hmLKImQHEq4lbR3UkrGo6239 rogid:D/OFB0z6DBE6ohjjHkvLHgK9jCI6239 intact-crc:F997D5FC81263CFE|rigid:GLugJ2/1UgYE6H8FfSfQ8uGd8ig false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19207 uniprotkb:Q22799 intact:EBI-323336|ensemblmetazoa:F08F8.2.1 intact:EBI-328324|ensemblmetazoa:T26A5.9.1|ensemblmetazoa:T26A5.9.2|ensemblmetazoa:T26A5.9.3 psi-mi:q19207_caeel(display_long)|uniprotkb:hmgr-1(gene name)|psi-mi:hmgr-1(display_short)|uniprotkb:F08F8.2(orf name)|uniprotkb:CELE_F08F8.2(orf name) psi-mi:dyl1_caeel(display_long)|uniprotkb:dlc-1(gene name)|psi-mi:dlc-1(display_short)|uniprotkb:T26A5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463357|imex:IM-11985-764 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498626.2|wormbase:F08F8.2|ensemblmetazoa:F08F8.2.1(transcript)|ensemblmetazoa:WBGene00017268(gene)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|dip:DIP-25409N|reactome:R-CEL-191273 refseq:NP_498422.1|wormbase:T26A5.9|reactome:R-CEL-6811436|reactome:R-CEL-5620924|dip:DIP-25449N|reactome:R-CEL-6807878|ensemblmetazoa:T26A5.9.1(transcript)|ensemblmetazoa:T26A5.9.2(transcript)|ensemblmetazoa:T26A5.9.3(transcript)|ensemblmetazoa:WBGene00001005(gene)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0030286"(dynein complex)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|reactome:R-CEL-1632852|reactome:R-CEL-3371497|reactome:R-CEL-6798695|reactome:R-CEL-9646399 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:n+mz8S2n9i40K01p7ZmGHnh/Bu86239 rogid:7Nfvom5nbqgSIuSse0QWDnAp6W46239 intact-crc:A83E230826936436|rigid:8aEsrWS8A/Cc8w1cXFe68wJPHHo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:O62136-1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-6463345|ensemblmetazoa:F07A5.1b.1|ensemblmetazoa:F07A5.1b.2 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:o62136-1(display_long)|uniprotkb:Protein opu-14(gene name synonym)|uniprotkb:opu-14(gene name synonym)|uniprotkb:F07A5.1(orf name)|uniprotkb:inx-14(gene name)|psi-mi:inx-14(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463350|imex:IM-11985-763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) ensemblmetazoa:F07A5.1b.1(transcript)|ensemblmetazoa:F07A5.1b.2(transcript)|ensemblmetazoa:WBGene00002136(gene)|intact:EBI-323877(isoform-parent) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:gJAuS7UPJj3igkQ9UZoghHxBnNw6239 intact-crc:172A45D2AF989694|rigid:PLuuuq8lqvEPP6bZKd7X7C0Y+7M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19749 uniprotkb:P10986 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 intact:EBI-321916|uniprotkb:Q7YSY2|ensemblmetazoa:M03F4.2a.1 psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:act4_caeel(display_long)|uniprotkb:act-4(gene name)|psi-mi:act-4(display_short)|uniprotkb:M03F4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463371|imex:IM-11985-766 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N refseq:NP_508841.1|wormbase:M03F4.2a|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|ensemblmetazoa:M03F4.2a.1(transcript)|ensemblmetazoa:WBGene00000066(gene)|go:"GO:0000281"(mitotic cytokinesis)|dip:DIP-27204N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 rogid:zehthX6Qo/gSO5k1j5Epcffr8Sc6239 intact-crc:C9353F1A19D76A3F|rigid:prfkBe2TLpu7DKRmFvdApbOerDM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34402 uniprotkb:Q21771 intact:EBI-1570073|ensemblmetazoa:F10E9.8.1 intact:EBI-2003035|ensemblmetazoa:R06C7.4.1|ensemblmetazoa:R06C7.4.2|ensemblmetazoa:R06C7.4.3 psi-mi:sas4_caeel(display_long)|uniprotkb:sas-4(gene name)|psi-mi:sas-4(display_short)|uniprotkb:F10E9.8(orf name) psi-mi:cpg3_caeel(display_long)|uniprotkb:cpg-3(gene name)|psi-mi:cpg-3(display_short)|uniprotkb:R06C7.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463364|imex:IM-11985-765 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498828.2|wormbase:F10E9.8|ensemblmetazoa:F10E9.8.1(transcript)|ensemblmetazoa:WBGene00004726(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0045185"(maintenance of protein location) refseq:NP_492047.1|wormbase:R06C7.4|interpro:IPR039260|ensemblmetazoa:R06C7.4.1(transcript)|ensemblmetazoa:R06C7.4.2(transcript)|ensemblmetazoa:R06C7.4.3(transcript)|ensemblmetazoa:WBGene00011063(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:aSfwIIQHxLSJJ+jn2dLOz96bjTQ6239 rogid:V38DzjjqUDSlmDBBv/cjHuldOjs6239 intact-crc:CD149720E44D46C3|rigid:Q42dST2Ub6SjAsWVngDDtFZyr7g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O18246 uniprotkb:Q19749 intact:EBI-317099|ensemblmetazoa:Y57G11C.22a.1 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 psi-mi:o18246_caeel(display_long)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:CELE_Y57G11C.22(orf name)|uniprotkb:Y57G11C.22(orf name) psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463378|imex:IM-11985-767 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041046.1|wormbase:Y57G11C.22a|ensemblmetazoa:WBGene00013317(gene)|ensemblmetazoa:Y57G11C.22a.1(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-27078N refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:EwNg/0sCGH1I5xMzixpfij4S4Gk6239 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 intact-crc:0CC1EA713A0B44C0|rigid:MeYqI3O2csxXHcIk9pzkZrRxLrU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q93568 intact:EBI-6463388 intact:EBI-320430|ensemblmetazoa:F25H2.4.1 intact:EBI-6306447 psi-mi:q93568_caeel(display_long)|uniprotkb:F25H2.4(orf name)|uniprotkb:CELE_F25H2.4(orf name) psi-mi:ebi6306447(display_short)|psi-mi:EBI-6463388(display_long)|intact:Y57G7A.10b(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463385|imex:IM-11985-768 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492760.1|wormbase:F25H2.4|ensemblmetazoa:F25H2.4.1(transcript)|ensemblmetazoa:WBGene00009118(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|dip:DIP-25164N - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZDVUL6val0TTUcqMb1WCdGjFKhA6239 - intact-crc:DDFD781A1D7E0311 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7JL40 uniprotkb:Q22866-2 intact:EBI-2003280|ensemblmetazoa:F25H5.3c.1|ensemblmetazoa:F25H5.3c.2 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:q7jl40_caeel(display_long)|uniprotkb:F25H5.3(orf name)|uniprotkb:pyk-1(gene name)|psi-mi:pyk-1(display_short)|uniprotkb:CELE_F25H5.3(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463403|imex:IM-11985-770 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021411.1|wormbase:F25H5.3c|interpro:IPR001697(Pyruvate kinase)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR018209|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR040442|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR036918|ensemblmetazoa:F25H5.3c.1(transcript)|ensemblmetazoa:F25H5.3c.2(transcript)|ensemblmetazoa:WBGene00009126(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006096"(glycolytic process)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:qY9iMmQxHnIJzgtfHMkwT0nCMvM6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:A033179B2253EB9E|rigid:yKnA7gvtiSWN/MskI5E9akTWlXM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17836 uniprotkb:Q22866-2 intact:EBI-2003258|ensemblmetazoa:F25H5.3a.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:o17836_caeel(display_long)|uniprotkb:F25H5.3(orf name)|uniprotkb:pyk-1(gene name)|psi-mi:pyk-1(display_short)|uniprotkb:CELE_F25H5.3(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463396|imex:IM-11985-769 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492458.1|wormbase:F25H5.3a|dip:DIP-25767N|ensemblmetazoa:F25H5.3a.1(transcript)|ensemblmetazoa:WBGene00009126(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006096"(glycolytic process)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442 intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LUf9wjXVVkAmu62ya7lOivnWkkk6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:22A662F290F001F7|rigid:vq3+WgmpZXSPOXYzJbCxW4kSkSc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:O44781 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-331944|ensemblmetazoa:F33D11.10.1 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:o44781_caeel(display_long)|uniprotkb:F33D11.10(orf name)|uniprotkb:CELE_F33D11.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463410|imex:IM-11985-771 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) refseq:NP_491703.1|wormbase:F33D11.10|dip:DIP-27243N|ensemblmetazoa:F33D11.10.1(transcript)|ensemblmetazoa:WBGene00018007(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071048"|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0016787"(hydrolase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:yl7i4pfqQXlZ+Z90Bssucpen6UQ6239 intact-crc:89E9B77D1DFA9E2F|rigid:7OAw5jf3sExGAVcbMqQHHAveXjU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21993 uniprotkb:Q20052 intact:EBI-323701|ensemblmetazoa:R151.9.1 intact:EBI-314913|ensemblmetazoa:F35G12.9.1|ensemblmetazoa:F35G12.9.2 psi-mi:pfd5_caeel(display_long)|uniprotkb:R151.9(orf name)|uniprotkb:pfd-5(gene name)|psi-mi:pfd-5(display_short) psi-mi:apc11_caeel(display_long)|uniprotkb:apc-11(gene name)|psi-mi:apc-11(display_short)|uniprotkb:F35G12.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463417|imex:IM-11985-772 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498582.1|wormbase:R151.9|ensemblmetazoa:WBGene00020112(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|ensemblmetazoa:R151.9.1(transcript)|dip:DIP-25712N refseq:NP_497937.1|wormbase:F35G12.9|ensemblmetazoa:F35G12.9.1(transcript)|ensemblmetazoa:F35G12.9.2(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|ensemblmetazoa:WBGene00000145(gene)|dip:DIP-24995N|reactome:R-CEL-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:vpZze2rqh9a2h5G80I7F5Xn2Css6239 rogid:11SdvWjkFNUyCv4arePb6BEXKEg6239 intact-crc:21817C01093E723E|rigid:PKoLBgV3OgVUkBFNWU8DTt2W/go false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20052 uniprotkb:Q22866-2 intact:EBI-314913|ensemblmetazoa:F35G12.9.1|ensemblmetazoa:F35G12.9.2 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:apc11_caeel(display_long)|uniprotkb:apc-11(gene name)|psi-mi:apc-11(display_short)|uniprotkb:F35G12.9(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463424|imex:IM-11985-773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497937.1|wormbase:F35G12.9|ensemblmetazoa:F35G12.9.1(transcript)|ensemblmetazoa:F35G12.9.2(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024991|ensemblmetazoa:WBGene00000145(gene)|dip:DIP-24995N|reactome:R-CEL-983168 intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:11SdvWjkFNUyCv4arePb6BEXKEg6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:19DE405A44A5ABC7|rigid:VAAgc8bG0aGOy/2dFAbCckrwRzQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVP0 uniprotkb:O16500 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 intact:EBI-313836|ensemblmetazoa:C03A7.4.1 psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:o16500_caeel(display_long)|uniprotkb:abu-15(gene name)|psi-mi:abu-15(display_short)|uniprotkb:CELE_C03A7.4(orf name)|uniprotkb:C03A7.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463431|imex:IM-11985-774 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) refseq:NP_504382.1|wormbase:C03A7.4|ensemblmetazoa:C03A7.4.1(transcript)|ensemblmetazoa:WBGene00004099(gene)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0060465"(pharynx development)|dip:DIP-26806N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 rogid:BFq/tDoOjfenHaNvj1ex+bLBsdE6239 intact-crc:6CD1E2737BC35BC2|rigid:RVq8BlGl41pYb6KEAeonidJvzCo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVP0 uniprotkb:Q17770 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 intact:EBI-323711|intact:EBI-2003473|ensemblmetazoa:C07A12.4a.1|ensemblmetazoa:C07A12.4a.2 psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:pdi2_caeel(display_long)|uniprotkb:pdi-2(gene name)|psi-mi:pdi-2(display_short)|uniprotkb:C07A12.4(orf name)|uniprotkb:PDI 1(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463438|imex:IM-11985-775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) refseq:NP_508778.1|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043412"(macromolecule modification)|go:"GO:0080058"(protein deglutathionylation)|ensemblmetazoa:C07A12.4a.1(transcript)|ensemblmetazoa:C07A12.4a.2(transcript)|ensemblmetazoa:WBGene00003963(gene)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|reactome:R-CEL-381426|reactome:R-CEL-8957275|interpro:IPR036249|reactome:R-CEL-1650814|wormbase:C07A12.4 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 rogid:LG6eowqHDBql5FiI/CPZsQ65EKA6239 intact-crc:C59E2243B3BE9E37|rigid:BmGxKn0r73vM+pWLypL1kGu3+9Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVP0 intact:EBI-6463445 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 - psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:g8jy07_caeel(display_short)|psi-mi:EBI-6463445(display_long)|uniprotkb:C07A12.4(orf name)|uniprotkb:pdi-2(gene name)|psi-mi:pdi-2(display_short)|uniprotkb:CELE_C07A12.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463450|imex:IM-11985-776 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) uniprotkb:G8JY07(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 rogid:8iWbZdnCdTei7y2HCjHFlPzMndI6239 intact-crc:53C8987CE95857E5|rigid:TPbG1HoT013GAdoHAEtXBuWcQ4A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVP0 uniprotkb:Q22866-2 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463457|imex:IM-11985-777 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:D9E86BE9D4370927|rigid:ypIDGFphK89YKmXiWSsC0X+GikI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVP0 uniprotkb:Q8I4B8 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 intact:EBI-896114|ensemblmetazoa:Y69H2.3d.1 psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:q8i4b8_caeel(display_long)|uniprotkb:Y69H2.3(orf name)|uniprotkb:CELE_Y69H2.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463471|imex:IM-11985-779 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|refseq:NP_507645.2|wormbase:Y69H2.3d|interpro:IPR036084|ensemblmetazoa:WBGene00013481(gene)|ensemblmetazoa:Y69H2.3d.1(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 rogid:WWyYI5bFrN3aRkmT8XHP+rTedNA6239 intact-crc:C01BEDAADFF9DF2F|rigid:bIydoKcFvNqN+cxxfb4FdsVP2As false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8I4B9 uniprotkb:Q9XVP0 intact:EBI-2003503|ensemblmetazoa:Y69H2.3c.1 intact:EBI-2003455|ensemblmetazoa:F36A2.6.1 psi-mi:q8i4b9_caeel(display_long)|uniprotkb:Y69H2.3(orf name)|uniprotkb:CELE_Y69H2.3(orf name) psi-mi:rs15_caeel(display_long)|uniprotkb:rps-15(gene name)|psi-mi:rps-15(display_short)|uniprotkb:F36A2.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463464|imex:IM-11985-778 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|refseq:NP_507642.2|wormbase:Y69H2.3c|interpro:IPR036084|ensemblmetazoa:WBGene00013481(gene)|ensemblmetazoa:Y69H2.3c.1(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region) refseq:NP_492384.1|wormbase:F36A2.6|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR020934|interpro:IPR023575|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-156827|reactome:R-CEL-72649|reactome:R-CEL-72706|ensemblmetazoa:F36A2.6.1(transcript)|ensemblmetazoa:WBGene00004484(gene)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022627"(cytosolic small ribosomal subunit) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:boiIKAGhaLP2VEL2GekbtSSZc8w6239 rogid:J5JHOvVyvxbJ7tOOhzWzNwT2sOs6239 intact-crc:A434628E84F26F2F|rigid:esksZtJE/643ii0YbM4X94aAUus false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20351 uniprotkb:P34604 intact:EBI-2003656|uniprotkb:Q8T8N1|ensemblmetazoa:F42G9.8.1 intact:EBI-313831|ensemblmetazoa:ZK1098.4.1 psi-mi:tpstb_caeel(display_long)|uniprotkb:Tyrosylprotein sulfotransferase(gene name synonym)|uniprotkb:F42G9.8(orf name)|uniprotkb:tpst-2(gene name)|psi-mi:tpst-2(display_short) psi-mi:ei2ba_caeel(display_long)|uniprotkb:ZK1098.4(orf name)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463478|imex:IM-11985-780 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_497256.1|wormbase:F42G9.8|interpro:IPR026634|interpro:IPR027417|ensemblmetazoa:F42G9.8.1(transcript)|ensemblmetazoa:WBGene00018365(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006478"(peptidyl-tyrosine sulfation)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0008476"(protein-tyrosine sulfotransferase activity) reactome:R-CEL-72731|refseq:NP_499106.1|wormbase:ZK1098.4|ensemblmetazoa:WBGene00014221(gene)|ensemblmetazoa:ZK1098.4.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|dip:DIP-26550N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:S6qylnnMtTn+mWQWGCSzFCCY4/s6239 rogid:1RBLZL4hmLKImQHEq4lbR3UkrGo6239 intact-crc:31189F1181963806|rigid:xr44dB+FxhfAwdq/kWk+r2VJ2do false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39745-1 uniprotkb:O18246 intact:EBI-6455829|ensemblmetazoa:F43C1.2b.1 intact:EBI-317099|ensemblmetazoa:Y57G11C.22a.1 psi-mi:p39745-1(display_long)|uniprotkb:MAP kinase sur-1(gene name synonym)|uniprotkb:sur-1(gene name synonym)|uniprotkb:F43C1.2(orf name)|uniprotkb:mpk-1(gene name)|psi-mi:mpk-1(display_short) psi-mi:o18246_caeel(display_long)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:CELE_Y57G11C.22(orf name)|uniprotkb:Y57G11C.22(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463485|imex:IM-11985-781 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:F43C1.2b.1(transcript)|ensemblmetazoa:WBGene00003401(gene)|intact:EBI-321013(isoform-parent) refseq:NP_001041046.1|wormbase:Y57G11C.22a|ensemblmetazoa:WBGene00013317(gene)|ensemblmetazoa:Y57G11C.22a.1(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-27078N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:LYuzbHHFnb3i+QM8G8dPajCX6/s6239 rogid:EwNg/0sCGH1I5xMzixpfij4S4Gk6239 intact-crc:42EE6234D8211AB7|rigid:/1WYHQXAAGQAe1QXhH8Hbi4nU1Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECU1 uniprotkb:Q17962 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 intact:EBI-2003707|ensemblmetazoa:C14B1.3.1 psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:q17962_caeel(display_long)|uniprotkb:C14B1.3(orf name)|uniprotkb:CELE_C14B1.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463492|imex:IM-11985-782 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 refseq:NP_497748.1|wormbase:C14B1.3|interpro:IPR007397(F-box associated region)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR008979(Galactose-binding like)|interpro:IPR039752|interpro:IPR036047|reactome:R-CEL-8951664|reactome:R-CEL-983168|ensemblmetazoa:C14B1.3.1(transcript)|ensemblmetazoa:WBGene00007574(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 rogid:zqI/cAAbFcJTj/3mjih6SyZZM4E6239 intact-crc:9FF68281AA2285CD|rigid:1/N5bCrp2uxRzsagQIHKpr8NM3k false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P91305 uniprotkb:G5ECU1 intact:EBI-2003766|ensemblmetazoa:F46F11.6.1|ensemblmetazoa:F46F11.6.2 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 psi-mi:p91305_caeel(display_long)|uniprotkb:xrep-4(gene name)|psi-mi:xrep-4(display_short)|uniprotkb:CELE_F46F11.6(orf name)|uniprotkb:F46F11.6(orf name) psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463499|imex:IM-11985-783 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001810(Cyclin-like F-box)|refseq:NP_491644.2|wormbase:F46F11.6|ensemblmetazoa:F46F11.6.1(transcript)|ensemblmetazoa:F46F11.6.2(transcript)|ensemblmetazoa:WBGene00018509(gene) interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:eqT2O6O6Avk9wBF4vVm7nqZFvOw6239 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 intact-crc:9B49508BC715B492|rigid:sOQNNe1YqM7zNjVm5lDhCvrQ2Uw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09543 uniprotkb:Q17948 intact:EBI-322806|ensemblmetazoa:F48E8.5.1|ensemblmetazoa:F48E8.5.2 intact:EBI-2003791|ensemblmetazoa:C13G3.3a.1|ensemblmetazoa:C13G3.3a.2 psi-mi:2aaa_caeel(display_long)|uniprotkb:F48E8.5(orf name)|uniprotkb:Protein phosphatase PP2A regulatory subunit A(gene name synonym)|uniprotkb:paa-1(gene name)|psi-mi:paa-1(display_short) psi-mi:q17948_caeel(display_long)|uniprotkb:pptr-2(gene name)|psi-mi:pptr-2(display_short)|uniprotkb:C13G3.3(orf name)|uniprotkb:CELE_C13G3.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463513|imex:IM-11985-785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498162.2|wormbase:F48E8.5|reactome:R-CEL-69231|reactome:R-CEL-198753|reactome:R-CEL-202670|reactome:R-CEL-2995383|reactome:R-CEL-69273|ensemblmetazoa:F48E8.5.1(transcript)|ensemblmetazoa:F48E8.5.2(transcript)|ensemblmetazoa:WBGene00003901(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043186"(P granule)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|reactome:R-CEL-195253|dip:DIP-26927N|reactome:R-CEL-196299|reactome:R-CEL-975957|reactome:R-CEL-5673000|reactome:R-CEL-5675221|reactome:R-CEL-389513|reactome:R-CEL-6811558 refseq:NP_505808.1|wormbase:C13G3.3a|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|ensemblmetazoa:C13G3.3a.1(transcript)|ensemblmetazoa:C13G3.3a.2(transcript)|ensemblmetazoa:WBGene00007554(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:9aApJ05VzQgGuaJ65kMPqQRBEb06239 rogid:lhWnAzQ/T/bAo2mIxm6r2W949Rs6239 intact-crc:298315E81DD0342C|rigid:EyiI40NvUJ353kxqaEjLE7xeRys false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECU1 uniprotkb:O16525 intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4 intact:EBI-329491|ensemblmetazoa:T05H4.2.1 psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name) psi-mi:o16525_caeel(display_long)|uniprotkb:fbxa-196(gene name)|psi-mi:fbxa-196(display_short)|uniprotkb:T05H4.2(orf name)|uniprotkb:CELE_T05H4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463506|imex:IM-11985-784 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937 refseq:NP_504642.1|wormbase:T05H4.2|dip:DIP-24854N|ensemblmetazoa:T05H4.2.1(transcript)|ensemblmetazoa:WBGene00020265(gene)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002900(Protein of unknown function DUF38, Caenorhabditis species)|interpro:IPR040161|interpro:IPR041426 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239 rogid:GFWTlgcyQxnkQ+h3CS6tfS/2zd86239 intact-crc:E53963FC0DC71664|rigid:zdV6cOwB1AsgQi7RL5gzFNTgDq4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09543 uniprotkb:Q9U3Q1 intact:EBI-322806|ensemblmetazoa:F48E8.5.1|ensemblmetazoa:F48E8.5.2 intact:EBI-2003803|ensemblmetazoa:C13G3.3b.1|ensemblmetazoa:C13G3.3b.2 psi-mi:2aaa_caeel(display_long)|uniprotkb:F48E8.5(orf name)|uniprotkb:Protein phosphatase PP2A regulatory subunit A(gene name synonym)|uniprotkb:paa-1(gene name)|psi-mi:paa-1(display_short) psi-mi:q9u3q1_caeel(display_long)|uniprotkb:pptr-2(gene name)|psi-mi:pptr-2(display_short)|uniprotkb:C13G3.3(orf name)|uniprotkb:CELE_C13G3.3(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463520|imex:IM-11985-786 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498162.2|wormbase:F48E8.5|reactome:R-CEL-69231|reactome:R-CEL-198753|reactome:R-CEL-202670|reactome:R-CEL-2995383|reactome:R-CEL-69273|ensemblmetazoa:F48E8.5.1(transcript)|ensemblmetazoa:F48E8.5.2(transcript)|ensemblmetazoa:WBGene00003901(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043186"(P granule)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|reactome:R-CEL-195253|dip:DIP-26927N|reactome:R-CEL-196299|reactome:R-CEL-975957|reactome:R-CEL-5673000|reactome:R-CEL-5675221|reactome:R-CEL-389513|reactome:R-CEL-6811558 refseq:NP_505807.1|wormbase:C13G3.3b|interpro:IPR016024(Armadillo-type fold)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|ensemblmetazoa:C13G3.3b.1(transcript)|ensemblmetazoa:C13G3.3b.2(transcript)|ensemblmetazoa:WBGene00007554(gene)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:9aApJ05VzQgGuaJ65kMPqQRBEb06239 rogid:G9Q8c77kert4RRWo7+MDa1GbhoE6239 intact-crc:0B1D3DA9366AA641|rigid:goOhRy441ORKld4lgVn1NO4m0c8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28548-2 uniprotkb:Q9XTF3-3 intact:EBI-317790|ensemblmetazoa:T01G9.6b.1|ensemblmetazoa:T01G9.6b.2|ensemblmetazoa:T01G9.6b.3 intact:EBI-6458160|ensemblmetazoa:F49E11.1c.1 psi-mi:p28548-2(display_long)|uniprotkb:kin-10(gene name)|psi-mi:kin-10(display_short)|uniprotkb:kin-5(gene name synonym)|uniprotkb:T01G9.6(orf name) psi-mi:q9xtf3-3(display_long)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:F49E11.1(orf name)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463527|imex:IM-11985-787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-317777(csk2b_caeel)|ensemblmetazoa:T01G9.6b.1(transcript)|ensemblmetazoa:T01G9.6b.2(transcript)|ensemblmetazoa:T01G9.6b.3(transcript)|ensemblmetazoa:WBGene00002196(gene) intact:EBI-2005616(isoform-parent)|ensemblmetazoa:F49E11.1c.1(transcript)|ensemblmetazoa:WBGene00003150(gene) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:PJExG7+45zVdDGoO35vcIyGkqxs6239 rogid:q+r0vN0DzQfPQs5H4lzQOgECK1k6239 intact-crc:46E6922C0CE65D1E|rigid:seQ7APhtxYUB03ZkvG9bzFUaibg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6463534 uniprotkb:Q9XTF3-3 intact:EBI-6306455 intact:EBI-6458160|ensemblmetazoa:F49E11.1c.1 psi-mi:ebi6306455(display_short)|psi-mi:EBI-6463534(display_long)|intact:ZK856.12(author assigned name) psi-mi:q9xtf3-3(display_long)|uniprotkb:Dual specificity Yak1-related kinase mbk-2(gene name synonym)|uniprotkb:Minibrain Kinase 2(gene name synonym)|uniprotkb:F49E11.1(orf name)|uniprotkb:mbk-2(gene name)|psi-mi:mbk-2(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463538|imex:IM-11985-788 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - intact:EBI-2005616(isoform-parent)|ensemblmetazoa:F49E11.1c.1(transcript)|ensemblmetazoa:WBGene00003150(gene) psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:q+r0vN0DzQfPQs5H4lzQOgECK1k6239 intact-crc:B07CC6D102520835 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O44740 uniprotkb:P34808-2 intact:EBI-323243|ensemblmetazoa:F57B10.12.1 intact:EBI-521381|ensemblmetazoa:T01G9.5b.1 psi-mi:mei2_caeel(display_long)|uniprotkb:mei-2(gene name)|psi-mi:mei-2(display_short)|uniprotkb:F57B10.12(orf name) psi-mi:p34808-2(display_long)|uniprotkb:mei-1(gene name)|psi-mi:mei-1(display_short)|uniprotkb:Katanin p60 ATPase-containing subunit A1(gene name synonym)|uniprotkb:p60 katanin(gene name synonym)|uniprotkb:T01G9.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463545|imex:IM-11985-789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491894.1|wormbase:F57B10.12|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008352"(katanin complex)|ensemblmetazoa:F57B10.12.1(transcript)|ensemblmetazoa:WBGene00003184(gene)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001940"(male pronucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0051013"(microtubule severing)|go:"GO:0051301"(cell division)|interpro:IPR028021|dip:DIP-27215N intact:EBI-323248(mei1_caeel)|ensemblmetazoa:T01G9.5b.1(transcript)|ensemblmetazoa:WBGene00003183(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:HkLWJzdRNw3NMipE4Q42A4cT7ks6239 rogid:v4S6u0FwofuXf9drTJYEBlLDykE6239 intact-crc:FABC4EE38DC80301|rigid:zn7dVjPBLPveVLSAszRE/QZSIzY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GT24 uniprotkb:Q20183 intact:EBI-323555|uniprotkb:O01903|ensemblmetazoa:F59E12.2.1|ensemblmetazoa:F59E12.2.2 intact:EBI-2004036|ensemblmetazoa:F38H4.7.1|ensemblmetazoa:F38H4.7.2 psi-mi:zyg1_caeel(display_long)|uniprotkb:zyg-1(gene name)|psi-mi:zyg-1(display_short)|uniprotkb:F59E12.2(orf name)|uniprotkb:Zygote defective protein 1(gene name synonym) psi-mi:q20183_caeel(display_long)|uniprotkb:tag-30(gene name)|psi-mi:tag-30(display_short)|uniprotkb:CELE_F38H4.7(orf name)|uniprotkb:F38H4.7(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463552|imex:IM-11985-790 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495103.1|wormbase:F59E12.2|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0051225"(spindle assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|ensemblmetazoa:F59E12.2.1(transcript)|ensemblmetazoa:F59E12.2.2(transcript)|ensemblmetazoa:WBGene00006988(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0106311"|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1904779"(regulation of protein localization to centrosome)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR040733|interpro:IPR040734|rcsb pdb:4NKB|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-24892N refseq:NP_502244.1|wormbase:F38H4.7|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR012983(PHR)|interpro:IPR038648|reactome:R-CEL-8951664|reactome:R-CEL-983168|ensemblmetazoa:F38H4.7.1(transcript)|ensemblmetazoa:F38H4.7.2(transcript)|ensemblmetazoa:WBGene00006415(gene)|go:"GO:0000932"(P-body)|go:"GO:0005829"(cytosol)|go:"GO:0022008"(neurogenesis) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:bW56U+tOCdP8UXKTudspR9Oi4/Q6239 rogid:2bAdXtNgxdnDrzU8rlGU0ikFZhE6239 intact-crc:07D6A6FE97166AA6|rigid:l/tTM34J2qNcTyS70sufpUAIcO8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:Q9GT24 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-323555|uniprotkb:O01903|ensemblmetazoa:F59E12.2.1|ensemblmetazoa:F59E12.2.2 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:zyg1_caeel(display_long)|uniprotkb:zyg-1(gene name)|psi-mi:zyg-1(display_short)|uniprotkb:F59E12.2(orf name)|uniprotkb:Zygote defective protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463559|imex:IM-11985-791 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) refseq:NP_495103.1|wormbase:F59E12.2|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008104"(protein localization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045977"(positive regulation of mitotic cell cycle, embryonic)|go:"GO:0051225"(spindle assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090169"(regulation of spindle assembly)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|ensemblmetazoa:F59E12.2.1(transcript)|ensemblmetazoa:F59E12.2.2(transcript)|ensemblmetazoa:WBGene00006988(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0106311"|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1904779"(regulation of protein localization to centrosome)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR040733|interpro:IPR040734|rcsb pdb:4NKB|go:"GO:0106310"(protein serine kinase activity)|dip:DIP-24892N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:bW56U+tOCdP8UXKTudspR9Oi4/Q6239 intact-crc:FD577A3182DEF4F2|rigid:05+5OP2mFNvvdFadheNt1gIx7CM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:P34509 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463573|imex:IM-11985-793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 intact-crc:5ACD9BD032FC4273|rigid:2gPxkQFt0ewbgveupQ6YFpHaFcs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6AHR3 uniprotkb:P34509 intact:EBI-2004092|ensemblmetazoa:R151.2d.1|ensemblmetazoa:R151.2d.2 intact:EBI-2002586|ensemblmetazoa:K06H7.1.1 psi-mi:q6ahr3_caeel(display_long)|uniprotkb:CELE_R151.2(orf name)|uniprotkb:R151.2(orf name) psi-mi:ymx1_caeel(display_long)|uniprotkb:K06H7.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463566|imex:IM-11985-792 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022728.2|wormbase:R151.2d|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|reactome:R-CEL-73843|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|ensemblmetazoa:R151.2d.1(transcript)|ensemblmetazoa:R151.2d.2(transcript)|ensemblmetazoa:WBGene00020107(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity) refseq:NP_498769.1|wormbase:K06H7.1|interpro:IPR042317|ensemblmetazoa:K06H7.1.1(transcript)|ensemblmetazoa:WBGene00019455(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:SmYG/GkJZzhIxZFLnH6A+GvXG3c6239 rogid:0NShK+4O2ehvTMtJRKd7s5vSgeU6239 intact-crc:B4E9402E973B44AC|rigid:E09snxH8gQ0jWJXzlo6aDl3biFk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P92004 uniprotkb:Q9XU12 intact:EBI-316398|ensemblmetazoa:M04G12.1a.1 intact:EBI-325126|ensemblmetazoa:K11D9.1a.1 psi-mi:p92004_caeel(display_long)|uniprotkb:tag-260(gene name)|psi-mi:tag-260(display_short)|uniprotkb:ifbp-1(gene name synonym)|uniprotkb:CELE_M04G12.1(orf name)|uniprotkb:M04G12.1(orf name) psi-mi:q9xu12_caeel(display_long)|uniprotkb:klp-7(gene name)|psi-mi:klp-7(display_short)|uniprotkb:CELE_K11D9.1(orf name)|uniprotkb:K11D9.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463591|imex:IM-11985-795 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506317.2|wormbase:M04G12.1a|ensemblmetazoa:M04G12.1a.1(transcript)|ensemblmetazoa:WBGene00010867(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR022750|interpro:IPR044882|dip:DIP-25625N refseq:NP_001022677.1|wormbase:K11D9.1a|ensemblmetazoa:K11D9.1a.1(transcript)|ensemblmetazoa:WBGene00002219(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010938"(cytoplasmic microtubule depolymerization)|go:"GO:0018991"(oviposition)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|dip:DIP-26934N|reactome:R-CEL-983189 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:FLs6J7hoBsplRey7ut/ybxr5o4E6239 rogid:CHfEKYlTwlJs6zeaXZrs0KLrlSI6239 intact-crc:6C7B86E1FB2A64A7|rigid:RxT5K/U/HMrfOljYwX71QxvX9Jg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09410 intact:EBI-6463580 intact:EBI-2004414|ensemblmetazoa:K10D2.4.1 intact:EBI-6306441 psi-mi:emb1_caeel(display_long)|uniprotkb:emb-1(gene name)|psi-mi:emb-1(display_short)|uniprotkb:Abnormal embryogenesis protein 1(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 16 homolog(gene name synonym)|uniprotkb:apc-16(gene name synonym)|uniprotkb:K10D2.4(orf name) psi-mi:ebi6306441(display_short)|psi-mi:EBI-6463580(display_long)|intact:Y57A10A.24x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463584|imex:IM-11985-794 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_498098.1|wormbase:K10D2.4|ensemblmetazoa:K10D2.4.1(transcript)|ensemblmetazoa:WBGene00019630(gene)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle) - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:FEUHkBhYLsPjrKrBBV6Ik3hDbQw6239 - intact-crc:2836C321E48BC7D6 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O17286 uniprotkb:Q9XU12 intact:EBI-325152|ensemblmetazoa:W10D9.4a.1|uniprotkb:A0A0M7RFF4 intact:EBI-325126|ensemblmetazoa:K11D9.1a.1 psi-mi:nfyb1_caeel(display_long)|uniprotkb:nfyb-1(gene name)|psi-mi:nfyb-1(display_short)|uniprotkb:CAAT box DNA-binding protein subunit nfyb-1(gene name synonym)|uniprotkb:W10D9.4(orf name) psi-mi:q9xu12_caeel(display_long)|uniprotkb:klp-7(gene name)|psi-mi:klp-7(display_short)|uniprotkb:CELE_K11D9.1(orf name)|uniprotkb:K11D9.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463598|imex:IM-11985-796 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493740.1|ensemblmetazoa:W10D9.4a.1(transcript)|ensemblmetazoa:WBGene00021132(gene)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009888"(tissue development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0043204"(perikaryon)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR027113|wormbase:W10D9.4a|dip:DIP-25261N|wormbase:W10D9.4b|refseq:NP_001303801.1 refseq:NP_001022677.1|wormbase:K11D9.1a|ensemblmetazoa:K11D9.1a.1(transcript)|ensemblmetazoa:WBGene00002219(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0010938"(cytoplasmic microtubule depolymerization)|go:"GO:0018991"(oviposition)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:1903436"(regulation of mitotic cytokinetic process)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|dip:DIP-26934N|reactome:R-CEL-983189 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:lw5h4Vt6TTJTiU8Bsf29pumUufM6239 rogid:CHfEKYlTwlJs6zeaXZrs0KLrlSI6239 intact-crc:A3A79C7BC53D6903|rigid:mUldITI9KbbR/Qn4r66yEPiNsmY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EEK8 uniprotkb:P34604 intact:EBI-2004462|ensemblmetazoa:K11D9.2a.1 intact:EBI-313831|ensemblmetazoa:ZK1098.4.1 psi-mi:g5eek8_caeel(display_long)|uniprotkb:sca-1(gene name)|psi-mi:sca-1(display_short)|uniprotkb:mca-4(gene name synonym)|uniprotkb:CELE_K11D9.2(orf name)|uniprotkb:K11D9.2(orf name) psi-mi:ei2ba_caeel(display_long)|uniprotkb:ZK1098.4(orf name)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463605|imex:IM-11985-797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044492|uniprotkb:Q9XTG6(uniprot-removed-ac)|reactome:R-CEL-5578775|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|refseq:NP_499386.1|wormbase:K11D9.2a|reactome:R-CEL-418359|reactome:R-CEL-936837|interpro:IPR036412|ensemblmetazoa:K11D9.2a.1(transcript)|ensemblmetazoa:WBGene00004736(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030104"(water homeostasis)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0040024"(dauer larval development)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport) reactome:R-CEL-72731|refseq:NP_499106.1|wormbase:ZK1098.4|ensemblmetazoa:WBGene00014221(gene)|ensemblmetazoa:ZK1098.4.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|dip:DIP-26550N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:t7qbSVyzhZQeG5ESVzg9K4LPCrM6239 rogid:1RBLZL4hmLKImQHEq4lbR3UkrGo6239 intact-crc:C80C96C77F4AB5D0|rigid:PZu3grUA71aMiXSrfQXgmUewMDc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55853 uniprotkb:G5EBV0 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 intact:EBI-2004151|intact:EBI-2316422|uniprotkb:G5ECV8|uniprotkb:G5EE79|uniprotkb:G5EEP8|uniprotkb:Q56W01|ensemblmetazoa:F22E12.4a.1|ensemblmetazoa:F22E12.4a.2 psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:egl9_caeel(display_long)|uniprotkb:egl-9(gene name)|psi-mi:egl-9(display_short)|uniprotkb:Egg-laying defective protein 9(gene name synonym)|uniprotkb:Hypoxia-inducible factor-proline dioxygenase(gene name synonym)|uniprotkb:F22E12.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463612|imex:IM-11985-798 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 refseq:NP_001023832.1|refseq:NP_001023833.1|refseq:NP_001023834.1|refseq:NP_001041105.1|uniprotkb:Q565A4(uniprot-removed-ac)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|refseq:NP_741621.1|wormbase:F22E12.4a|wormbase:F22E12.4b|wormbase:F22E12.4c|wormbase:F22E12.4e|wormbase:F22E12.4d|reactome:R-CEL-1234176|ensemblmetazoa:F22E12.4a.1(transcript)|ensemblmetazoa:F22E12.4a.2(transcript)|ensemblmetazoa:WBGene00001178(gene)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0031543"(peptidyl-proline dioxygenase activity)|go:"GO:0031545"(peptidyl-proline 4-dioxygenase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0071456"(cellular response to hypoxia) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2015/07/17 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 rogid:a4HDpatGkHrKY66dCfsWuAsoOw46239 intact-crc:35563C312065D5D9|rigid:EjceT0PIbxEM/V6znQyGhtxJv1M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6463619 uniprotkb:P55853 intact:EBI-6306422 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:ebi6306422(display_short)|psi-mi:EBI-6463619(display_long)|intact:W02F12.4c(author assigned name) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463623|imex:IM-11985-799 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:7075463DDDB7366B false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:P55853 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-313647|ensemblmetazoa:K12C11.2.1 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:sumo_caeel(display_long)|uniprotkb:smo-1(gene name)|psi-mi:smo-1(display_short)|uniprotkb:smt3(gene name synonym)|uniprotkb:K12C11.2(orf name)|uniprotkb:Ubiquitin-like protein SMT3(gene name synonym)|uniprotkb:sumo(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463630|imex:IM-11985-800 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) reactome:R-CEL-3065679|reactome:R-CEL-3108214|refseq:NP_490842.1|wormbase:K12C11.2|reactome:R-CEL-3065676|reactome:R-CEL-3065678|go:"GO:0031386"(protein tag)|go:"GO:0005819"(spindle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071965"(multicellular organismal locomotion)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|interpro:IPR029071|go:"GO:0010468"(regulation of gene expression)|rcsb pdb:5XQM|go:"GO:0016925"(protein sumoylation)|ensemblmetazoa:K12C11.2.1(transcript)|ensemblmetazoa:WBGene00004888(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|reactome:R-CEL-3232118|reactome:R-CEL-4570464|reactome:R-CEL-4615885|reactome:R-CEL-5696395|reactome:R-CEL-3899300|reactome:R-CEL-877312|reactome:R-CEL-8866904|dip:DIP-25461N|reactome:R-CEL-4551638|reactome:R-CEL-4085377|reactome:R-CEL-4090294|reactome:R-CEL-3232142|reactome:R-CEL-3108232|reactome:R-CEL-9615933 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:g61eAkuThlnKztDVB05kFQUUBao6239 intact-crc:6758A461CFAD24F7|rigid:2KoUkf0O8UO5sOqTNtibHvemiXA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:Q23670 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-323996|uniprotkb:Q27509|ensemblmetazoa:K12D12.1.1 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:top2_caeel(display_long)|uniprotkb:top-2(gene name)|psi-mi:top-2(display_short)|uniprotkb:DNA topoisomerase II(gene name synonym)|uniprotkb:K12D12.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463637|imex:IM-11985-801 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) refseq:NP_496536.1|wormbase:K12D12.1|ensemblmetazoa:K12D12.1.1(transcript)|ensemblmetazoa:WBGene00010785(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006265"(DNA topological change)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0051306"(mitotic sister chromatid separation)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR034157|interpro:IPR036890|interpro:IPR031660|reactome:R-CEL-4615885|dip:DIP-27416N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:mMVe6/tBKCkNlRfJ3X08lsDKthg6239 intact-crc:6705BA83D6FA545C|rigid:mvHe3Y8ZjnoAPrlmu1HR9kj5+4A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 intact:EBI-6463644 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-6306399 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:ebi6306399(display_short)|psi-mi:EBI-6463644(display_long)|intact:K12D12.2x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463648|imex:IM-11985-802 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 - intact-crc:FFCA4CC9A9AA8F9A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10983 uniprotkb:P10986 intact:EBI-312653|uniprotkb:P10985 intact:EBI-321916|uniprotkb:Q7YSY2|ensemblmetazoa:M03F4.2a.1 psi-mi:act1_caeel(display_long)|uniprotkb:act-1(gene name)|psi-mi:act-1(display_short)|uniprotkb:T04C12.4(orf name)|uniprotkb:act-3(gene name)|psi-mi:act-3(display_short)|uniprotkb:T04C12.6(orf name) psi-mi:act4_caeel(display_long)|uniprotkb:act-4(gene name)|psi-mi:act-4(display_short)|uniprotkb:M03F4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463655|imex:IM-11985-803 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005524"(ATP binding)|go:"GO:0007517"(muscle organ development)|refseq:NP_505817.1|refseq:NP_505819.1|wormbase:T04C12.4|wormbase:T04C12.6|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|rcsb pdb:1D4X|go:"GO:0009790"(embryo development)|go:"GO:0030036"(actin cytoskeleton organization) refseq:NP_508841.1|wormbase:M03F4.2a|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045121"(membrane raft)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|ensemblmetazoa:M03F4.2a.1(transcript)|ensemblmetazoa:WBGene00000066(gene)|go:"GO:0000281"(mitotic cytokinesis)|dip:DIP-27204N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:FfocOk3zTuKPi2M4G/gWUnYn5Dc6239 rogid:zehthX6Qo/gSO5k1j5Epcffr8Sc6239 intact-crc:B6E51B1A4D9E6331|rigid:fw8dKBpf4bhsJzQLGEov5pQGp7o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P35129 uniprotkb:Q8WTJ8 intact:EBI-316050|ensemblmetazoa:M7.1.1 intact:EBI-321112|ensemblmetazoa:Y51F10.2a.1|ensemblmetazoa:Y51F10.2a.2 psi-mi:ubc2_caeel(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme 2(gene name synonym)|uniprotkb:let-70(gene name)|psi-mi:let-70(display_short)|uniprotkb:ubc-2(gene name synonym)|uniprotkb:M7.1(orf name)|uniprotkb:Ubiquitin-protein ligase 2(gene name synonym)|uniprotkb:Ubiquitin carrier protein 2(gene name synonym)|uniprotkb:Lethal protein 70(gene name synonym) psi-mi:q8wtj8_caeel(display_long)|uniprotkb:Y51F10.2(orf name)|uniprotkb:CELE_Y51F10.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463662|imex:IM-11985-804 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502065.1|wormbase:M7.1|reactome:R-CEL-201451|ensemblmetazoa:M7.1.1(transcript)|ensemblmetazoa:WBGene00002344(gene)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Z2U|dip:DIP-24306N|reactome:R-CEL-1234176|reactome:R-CEL-2173795|reactome:R-CEL-5689896|reactome:R-CEL-8866652|reactome:R-CEL-8866654|reactome:R-CEL-8951664|reactome:R-CEL-9033241|reactome:R-CEL-983168 refseq:NP_740796.1|ensemblmetazoa:WBGene00021763(gene)|ensemblmetazoa:Y51F10.2a.1(transcript)|ensemblmetazoa:Y51F10.2a.2(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|wormbase:Y51F10.2a|dip:DIP-26335N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:JMk9za/Hb0H6Q4ivtWEXiJLbycY6239 rogid:ecYf0rK4DGesDNxewp2Vg2bxK/Y6239 intact-crc:CFDAA77E0720536A|rigid:qk/qn460QwWobOwT32tC+lgJNRw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21735 uniprotkb:Q22866-2 intact:EBI-2004567|ensemblmetazoa:R05D11.3.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:ntf2_caeel(display_long)|uniprotkb:ran-4(gene name)|psi-mi:ran-4(display_short)|uniprotkb:R05D11.3(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463669|imex:IM-11985-805 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492322.1|wormbase:R05D11.3|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|ensemblmetazoa:R05D11.3.1(transcript)|ensemblmetazoa:WBGene00004305(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0044613"(nuclear pore central transport channel) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:MO3nF45y4Qnv1bnk707RFa3N6hU6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:CA27596834D0715D|rigid:vzj9defhXCVYyT+VsYRYXKDuOFw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:Q11178 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-2004606|uniprotkb:H2KYG7|uniprotkb:Q5TYM0|ensemblmetazoa:C05D10.1a.1 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:attf4_caeel(display_long)|uniprotkb:attf-4(gene name)|psi-mi:attf-4(display_short)|uniprotkb:C05D10.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463676|imex:IM-11985-806 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) wormbase:C05D10.1b|wormbase:C05D10.1c|refseq:NP_741168.1|wormbase:C05D10.1a|refseq:NP_001021144.1|refseq:NP_741169.1|interpro:IPR038839|ensemblmetazoa:C05D10.1a.1(transcript)|ensemblmetazoa:WBGene00015477(gene)|go:"GO:0003677"(DNA binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:7GpLzvQ39fyxdkVOZ2upOpVISGA6239 intact-crc:C269F478B2AC776F|rigid:qq1jWPcmQ5k05znOpq14/j7nR6E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 uniprotkb:O16393 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-327108|ensemblmetazoa:C17E7.4.1 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:o16393_caeel(display_long)|uniprotkb:C17E7.4(orf name)|uniprotkb:CELE_C17E7.4(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463683|imex:IM-11985-807 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) refseq:NP_504075.1|wormbase:C17E7.4|ensemblmetazoa:C17E7.4.1(transcript)|ensemblmetazoa:WBGene00015899(gene)|dip:DIP-27286N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 rogid:s954jANzz14pbfSW5Nr7WNVwg7w6239 intact-crc:ECF715D087BBC47A|rigid:9SK8LjgRybNtzsFDh1uG9/X1n6o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62333 intact:EBI-6463580 intact:EBI-2004341|ensemblmetazoa:R06A4.4b.1 intact:EBI-6306441 psi-mi:o62333_caeel(display_long)|uniprotkb:imb-2(gene name)|psi-mi:imb-2(display_short)|uniprotkb:CELE_R06A4.4(orf name)|uniprotkb:R06A4.4(orf name) psi-mi:ebi6306441(display_short)|psi-mi:EBI-6463580(display_long)|intact:Y57A10A.24x(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463690|imex:IM-11985-808 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_496988.1|wormbase:R06A4.4b|interpro:IPR040122|ensemblmetazoa:R06A4.4b.1(transcript)|ensemblmetazoa:WBGene00002076(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus) - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:x3+K0pCglRZFKz6r+OZBHn0lwX86239 - intact-crc:F5BA9916711310DA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19890 uniprotkb:Q09601-1 intact:EBI-2004797|ensemblmetazoa:F28H7.2.1 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:q19890_caeel(display_long)|uniprotkb:CELE_F28H7.2(orf name)|uniprotkb:F28H7.2(orf name) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463704|imex:IM-11985-810 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505742.1|wormbase:F28H7.2|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|ensemblmetazoa:F28H7.2.1(transcript)|ensemblmetazoa:WBGene00009236(gene)|go:"GO:0016491"(oxidoreductase activity) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:8VkCF7TcOBPli4+OW09+O5b/dFc6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:7E63D3B59A4CD12E|rigid:9Zw9//VC2VVu3c3JHwFCbRFe2Ew false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21774-1 uniprotkb:Q21774-2 intact:EBI-6457160|ensemblmetazoa:R06C7.5a.1|ensemblmetazoa:R06C7.5a.2 intact:EBI-2004718|ensemblmetazoa:R06C7.5b.1 psi-mi:q21774-1(display_long)|uniprotkb:adsl-1(gene name)|psi-mi:adsl-1(display_short)|uniprotkb:Adenylosuccinase(gene name synonym)|uniprotkb:R06C7.5(orf name) psi-mi:q21774-2(display_long)|uniprotkb:adsl-1(gene name)|psi-mi:adsl-1(display_short)|uniprotkb:Adenylosuccinase(gene name synonym)|uniprotkb:R06C7.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463697|imex:IM-11985-809 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2004707(isoform-parent)|ensemblmetazoa:R06C7.5a.1(transcript)|ensemblmetazoa:R06C7.5a.2(transcript)|ensemblmetazoa:WBGene00011064(gene) intact:EBI-2004707(isoform-parent)|ensemblmetazoa:R06C7.5b.1(transcript)|ensemblmetazoa:WBGene00011064(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:nsxIVDy+CvOUNUEFIYHsvkrV+wA6239 rogid:1tTA0JXV0dX6GL7kKY4xkuIQPCY6239 intact-crc:86E8B6DD3C9C33A3|rigid:fh75NjfvEEl6ZQcriOPLvq4KNRA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:Q09601-1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463711|imex:IM-11985-811 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:0C319BF9A92B6C1C|rigid:5pS6/ywCqB7Bg+WHVZIdXOzfLOA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-4 uniprotkb:Q09601-1 intact:EBI-1457302|ensemblmetazoa:Y105E8B.1f.1 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:q22866-4(display_long)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463718|imex:IM-11985-812 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(isoform-parent)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1f.1(transcript) intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BOZ4TItdaccLLBLhvCSjCEivD2A6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:D527F4BCBD7B653F|rigid:kI2AaWfIBvf6De7KmKLKcWIjrf8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34604 uniprotkb:Q09601-1 intact:EBI-313831|ensemblmetazoa:ZK1098.4.1 intact:EBI-6455756|ensemblmetazoa:R06F6.5b.1 psi-mi:ei2ba_caeel(display_long)|uniprotkb:ZK1098.4(orf name)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym) psi-mi:q09601-1(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym)|uniprotkb:Nucleoporin npp-19(gene name synonym)|uniprotkb:R06F6.5(orf name)|uniprotkb:npp-19(gene name)|psi-mi:npp-19(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463725|imex:IM-11985-813 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72731|refseq:NP_499106.1|wormbase:ZK1098.4|ensemblmetazoa:WBGene00014221(gene)|ensemblmetazoa:ZK1098.4.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|dip:DIP-26550N intact:EBI-2004755(isoform-parent)|ensemblmetazoa:R06F6.5b.1(transcript)|ensemblmetazoa:WBGene00003805(gene) psi-mi:"MI:0469"(intact) - isoform-comment:No experimental confirmation available. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:1RBLZL4hmLKImQHEq4lbR3UkrGo6239 rogid:s9MrFDynSAgRNNiCIfI1oEJJ4ug6239 intact-crc:8AD9C8355B938689|rigid:CGkkH+ILZ3Mm5OdpCry7F+Qz9h0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95ZQ3 uniprotkb:Q22866-2 intact:EBI-2004972|ensemblmetazoa:T02G5.9b.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:q95zq3_caeel(display_long)|uniprotkb:kars-1(gene name)|psi-mi:kars-1(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:CELE_T02G5.9(orf name)|uniprotkb:T02G5.9(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463732|imex:IM-11985-814 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495454.1|wormbase:T02G5.9b|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR044136|ensemblmetazoa:T02G5.9b.1(transcript)|ensemblmetazoa:WBGene00002238(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006430"(lysyl-tRNA aminoacylation) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:iQvw4aeBips00raW7AoVlOjdpXU6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:CC8D41850F8748C2|rigid:uf0pc3YOfjzZ3pbBHbaIPRQocF4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10984 uniprotkb:P10983 intact:EBI-316166|uniprotkb:O45744|ensemblmetazoa:T04C12.5.1|ensemblmetazoa:T04C12.5.2|ensemblmetazoa:T04C12.5.3 intact:EBI-312653|uniprotkb:P10985 psi-mi:act2_caeel(display_long)|uniprotkb:act-2(gene name)|psi-mi:act-2(display_short)|uniprotkb:T04C12.5(orf name) psi-mi:act1_caeel(display_long)|uniprotkb:act-1(gene name)|psi-mi:act-1(display_short)|uniprotkb:T04C12.4(orf name)|uniprotkb:act-3(gene name)|psi-mi:act-3(display_short)|uniprotkb:T04C12.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463746|imex:IM-11985-816 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_505818.1|wormbase:T04C12.5|reactome:R-CEL-114608|reactome:R-CEL-190873|reactome:R-CEL-196025|reactome:R-CEL-2029482|reactome:R-CEL-3928662|reactome:R-CEL-3928665|reactome:R-CEL-437239|reactome:R-CEL-4420097|reactome:R-CEL-445355|reactome:R-CEL-446353|reactome:R-CEL-5626467|reactome:R-CEL-5663213|reactome:R-CEL-5663220|reactome:R-CEL-5674135|reactome:R-CEL-8856828|reactome:R-CEL-8980692|reactome:R-CEL-9035034|ensemblmetazoa:T04C12.5.1(transcript)|ensemblmetazoa:T04C12.5.2(transcript)|ensemblmetazoa:T04C12.5.3(transcript)|ensemblmetazoa:WBGene00000064(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007111"(meiosis II cytokinesis)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0040011"(locomotion)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|dip:DIP-25116N go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005524"(ATP binding)|go:"GO:0007517"(muscle organ development)|refseq:NP_505817.1|refseq:NP_505819.1|wormbase:T04C12.4|wormbase:T04C12.6|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|rcsb pdb:1D4X|go:"GO:0009790"(embryo development)|go:"GO:0030036"(actin cytoskeleton organization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:pqXk6IfTnhM0CgPVRlu+EK57pDs6239 rogid:FfocOk3zTuKPi2M4G/gWUnYn5Dc6239 intact-crc:FE173E26BE519BD0|rigid:2W2ryqcm4AVFrQoGdCobjS33jos false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-4 uniprotkb:Q95ZQ3 intact:EBI-1457302|ensemblmetazoa:Y105E8B.1f.1 intact:EBI-2004972|ensemblmetazoa:T02G5.9b.1 psi-mi:q22866-4(display_long)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:q95zq3_caeel(display_long)|uniprotkb:kars-1(gene name)|psi-mi:kars-1(display_short)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)|uniprotkb:CELE_T02G5.9(orf name)|uniprotkb:T02G5.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463739|imex:IM-11985-815 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(isoform-parent)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1f.1(transcript) refseq:NP_495454.1|wormbase:T02G5.9b|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR018149|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR034762|interpro:IPR044136|ensemblmetazoa:T02G5.9b.1(transcript)|ensemblmetazoa:WBGene00002238(gene)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006430"(lysyl-tRNA aminoacylation) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:BOZ4TItdaccLLBLhvCSjCEivD2A6239 rogid:iQvw4aeBips00raW7AoVlOjdpXU6239 intact-crc:246C635CD5BEE8C3|rigid:HCCCI5IK5Iu3hn5SmHq5bMV5TdE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17868 uniprotkb:P34556 intact:EBI-314859|ensemblmetazoa:C09G4.3.1 intact:EBI-327309|ensemblmetazoa:T05G5.3.1|ensemblmetazoa:T05G5.3.2 psi-mi:cks1_caeel(display_long)|uniprotkb:cks-1(gene name)|psi-mi:cks-1(display_short)|uniprotkb:dom-6(gene name synonym)|uniprotkb:C09G4.3(orf name) psi-mi:cdk1_caeel(display_long)|uniprotkb:T05G5.3(orf name)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:cdk-1(gene name)|psi-mi:cdk-1(display_short)|uniprotkb:ncc-1(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463753|imex:IM-11985-817 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501457.1|wormbase:C09G4.3|ensemblmetazoa:C09G4.3.1(transcript)|ensemblmetazoa:WBGene00001051(gene)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR000789(Cyclin-dependent kinase, regulatory subunit)|interpro:IPR036858|dip:DIP-25964N|reactome:R-CEL-69231|reactome:R-CEL-187577 refseq:NP_001022747.1|wormbase:T05G5.3|reactome:R-CEL-5687128|reactome:R-CEL-110056|reactome:R-CEL-69273|reactome:R-CEL-176408|reactome:R-CEL-2500257|reactome:R-CEL-6804114|reactome:R-CEL-69478|ensemblmetazoa:T05G5.3.1(transcript)|ensemblmetazoa:T05G5.3.2(transcript)|ensemblmetazoa:WBGene00000405(gene)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051446"(positive regulation of meiotic cell cycle)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|dip:DIP-26477N|reactome:R-CEL-2299718|reactome:R-CEL-2565942|reactome:R-CEL-4419969|reactome:R-CEL-8878166 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OlpJM8zMwCqm6eB6A34tlx7WkrI6239 rogid:J7vmR2h39IuGCiugKb0MzSTbBlg6239 intact-crc:88CE35FE611DD08E|rigid:wq6h7cAa4tCaU64EjI2PSVg5FxE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86B36 uniprotkb:P34604 intact:EBI-6463760|ensemblmetazoa:T08B2.9b.1|ensemblmetazoa:T08B2.9b.2 intact:EBI-313831|ensemblmetazoa:ZK1098.4.1 psi-mi:q86b36_caeel(display_long)|uniprotkb:T08B2.9(orf name)|uniprotkb:fars-1(gene name)|psi-mi:fars-1(display_short)|uniprotkb:CELE_T08B2.9(orf name) psi-mi:ei2ba_caeel(display_long)|uniprotkb:ZK1098.4(orf name)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463765|imex:IM-11985-818 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T08B2.9b.1(transcript)|ensemblmetazoa:T08B2.9b.2(transcript)|ensemblmetazoa:WBGene00001497(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|refseq:NP_871804.1|wormbase:T08B2.9b reactome:R-CEL-72731|refseq:NP_499106.1|wormbase:ZK1098.4|ensemblmetazoa:WBGene00014221(gene)|ensemblmetazoa:ZK1098.4.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|dip:DIP-26550N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:KAsp81JoZmcL6zMe2pAzPL03pg86239 rogid:1RBLZL4hmLKImQHEq4lbR3UkrGo6239 intact-crc:43CAC10C3887F7E0|rigid:b181+SC5PrSL/UEZUhgq6A2AT2E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86NC2 uniprotkb:P34604 intact:EBI-6463772|ensemblmetazoa:T10E9.7.1 intact:EBI-313831|ensemblmetazoa:ZK1098.4.1 psi-mi:q86nc2_caeel(display_long)|uniprotkb:nuo-2(gene name)|psi-mi:nuo-2(display_short)|uniprotkb:CELE_T10E9.7(orf name)|uniprotkb:T10E9.7(orf name) psi-mi:ei2ba_caeel(display_long)|uniprotkb:ZK1098.4(orf name)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463777|imex:IM-11985-819 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:T10E9.7.1(transcript)|ensemblmetazoa:WBGene00020417(gene)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008340"(determination of adult lifespan)|reactome:R-CEL-6799198|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|refseq:NP_871796.1|wormbase:T10E9.7|interpro:IPR037232 reactome:R-CEL-72731|refseq:NP_499106.1|wormbase:ZK1098.4|ensemblmetazoa:WBGene00014221(gene)|ensemblmetazoa:ZK1098.4.1(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|dip:DIP-26550N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:UrEhFdMTDCIkrHLqzDwyjf4gbOs6239 rogid:1RBLZL4hmLKImQHEq4lbR3UkrGo6239 intact-crc:FAFF4CD77875AE59|rigid:r2TMMBYXWFBDPcKJci/zGmpwR6o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVI9 uniprotkb:O18246 intact:EBI-2005210|ensemblmetazoa:T12D8.6.1|ensemblmetazoa:T12D8.6.2 intact:EBI-317099|ensemblmetazoa:Y57G11C.22a.1 psi-mi:mlc5_caeel(display_long)|uniprotkb:mlc-5(gene name)|psi-mi:mlc-5(display_short)|uniprotkb:T12D8.6(orf name) psi-mi:o18246_caeel(display_long)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:CELE_Y57G11C.22(orf name)|uniprotkb:Y57G11C.22(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463784|imex:IM-11985-820 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499813.1|wormbase:T12D8.6|interpro:IPR011992(EF-Hand type)|interpro:IPR002048(Calcium-binding EF-hand)|reactome:R-CEL-445355|reactome:R-CEL-5627123|ensemblmetazoa:T12D8.6.1(transcript)|ensemblmetazoa:T12D8.6.2(transcript)|ensemblmetazoa:WBGene00011734(gene)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex) refseq:NP_001041046.1|wormbase:Y57G11C.22a|ensemblmetazoa:WBGene00013317(gene)|ensemblmetazoa:Y57G11C.22a.1(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-27078N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:VXlq5eXkAIEGib7yDeFZnekwX8I6239 rogid:EwNg/0sCGH1I5xMzixpfij4S4Gk6239 intact-crc:3C3EE6E33CC0171E|rigid:9PVtnjCdl5HA/Vh8nLdLLIUxYF0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q17958 uniprotkb:H2L099 intact:EBI-315152|ensemblmetazoa:C14A4.11.1 intact:EBI-315173|uniprotkb:H2L0A0|uniprotkb:H2L0A1|uniprotkb:Q6ABW4|ensemblmetazoa:T19A5.2a.1 psi-mi:pdc10_caeel(display_long)|uniprotkb:ccm-3(gene name)|psi-mi:ccm-3(display_short)|uniprotkb:Cerebral cavernous malformation protein 3(gene name synonym)|uniprotkb:C14A4.11(orf name) psi-mi:gck1_caeel(display_long)|uniprotkb:gck-1(gene name)|psi-mi:gck-1(display_short)|uniprotkb:T19A5.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463791|imex:IM-11985-821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496290.2|wormbase:C14A4.11|ensemblmetazoa:C14A4.11.1(transcript)|ensemblmetazoa:WBGene00007561(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035838"(growing cell tip)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0060562"(epithelial tube morphogenesis)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR009652(Protein of unknown function DUF1241)|dip:DIP-26279N uniprotkb:Q22553(uniprot-removed-ac)|wormbase:T19A5.2b|wormbase:T19A5.2c|wormbase:T19A5.2d|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-CEL-111465|reactome:R-CEL-75153|refseq:NP_001024141.1|refseq:NP_505310.2|refseq:NP_505311.3|refseq:NP_505309.1|wormbase:T19A5.2a|ensemblmetazoa:T19A5.2a.1(transcript)|ensemblmetazoa:WBGene00001526(gene)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0060281"(regulation of oocyte development)|go:"GO:0060562"(epithelial tube morphogenesis)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:2001137"(positive regulation of endocytic recycling) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Tz609yd54lwmufVflPgltHymh2w6239 rogid:pKSgv5U9LD0SrkEnPyb8cwvgEI06239 intact-crc:7EE91EAB8E692F0E|rigid:0x2SE5R7WLYXyPVPO1TRtvfC6ak false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O62197 uniprotkb:P91457 intact:EBI-2005147|ensemblmetazoa:F32A11.3.1 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:o62197_caeel(display_long)|uniprotkb:CELE_F32A11.3(orf name)|uniprotkb:F32A11.3(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463798|imex:IM-11985-822 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_496792.1|wormbase:F32A11.3|ensemblmetazoa:F32A11.3.1(transcript)|ensemblmetazoa:WBGene00009308(gene) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:+uHSb6OFegn3yXAd+qN6N9pWyD46239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:212E7346203E3FE3|rigid:vej/TTamkBVVVu3ImD6Hf3ugL4E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19989 uniprotkb:P91457 intact:EBI-322167|ensemblmetazoa:F33G12.5.1|ensemblmetazoa:F33G12.5.2 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:q19989_caeel(display_long)|uniprotkb:golg-2(gene name)|psi-mi:golg-2(display_short)|uniprotkb:CELE_F33G12.5(orf name)|uniprotkb:F33G12.5(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463805|imex:IM-11985-823 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_494929.3|wormbase:F33G12.5|ensemblmetazoa:F33G12.5.1(transcript)|ensemblmetazoa:F33G12.5.2(transcript)|ensemblmetazoa:WBGene00018017(gene)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0007030"(Golgi organization)|go:"GO:0032580"(Golgi cisterna membrane)|interpro:IPR024858|interpro:IPR043976|dip:DIP-27310N|reactome:R-CEL-162658|reactome:R-CEL-204005|reactome:R-CEL-6807878 refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:EAIYo5lIE2I9/VNz5LJZDUtgu006239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:AC1C86F4CEFBB57E|rigid:yvovZulRN0sst9oMrCQrzmMYpA4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7K6X4 uniprotkb:P91457 intact:EBI-2005324|ensemblmetazoa:Y56A3A.17.1|ensemblmetazoa:Y56A3A.17.2 intact:EBI-2004585|ensemblmetazoa:T19B4.2.1|ensemblmetazoa:T19B4.2.2 psi-mi:q7k6x4_caeel(display_long)|uniprotkb:npp-16(gene name)|psi-mi:npp-16(display_short)|uniprotkb:CELE_Y56A3A.17(orf name)|uniprotkb:Y56A3A.17(orf name) psi-mi:p91457_caeel(display_long)|uniprotkb:npp-7(gene name)|psi-mi:npp-7(display_short)|uniprotkb:CELE_T19B4.2(orf name)|uniprotkb:T19B4.2(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463812|imex:IM-11985-824 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:Y56A3A.17|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_499551.1|ensemblmetazoa:WBGene00003802(gene)|ensemblmetazoa:Y56A3A.17.1(transcript)|ensemblmetazoa:Y56A3A.17.2(transcript)|go:"GO:0006606"(protein import into nucleus) refseq:NP_491665.1|wormbase:T19B4.2|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR026054|ensemblmetazoa:T19B4.2.1(transcript)|ensemblmetazoa:T19B4.2.2(transcript)|ensemblmetazoa:WBGene00003793(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:akWT64IBGe7kByryIUnMe0jBV1A6239 rogid:vo9jyN+b1uoCXeoNxsjQIunCjpw6239 intact-crc:0B4E77C5C6502C8C|rigid:VEc70Ddq5MohVKhdq3NZuBpva2Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9GZH2 intact:EBI-6463819 intact:EBI-316221|ensemblmetazoa:T22D1.10.1|ensemblmetazoa:T22D1.10.2 intact:EBI-6306348 psi-mi:ruvb2_caeel(display_long)|uniprotkb:ruvb-2(gene name)|psi-mi:ruvb-2(display_short)|uniprotkb:Reptin(gene name synonym)|uniprotkb:T22D1.10(orf name) psi-mi:ebi6306348(display_short)|psi-mi:EBI-6463819(display_long)|intact:C27H6.2(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463823|imex:IM-11985-825 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR027417|refseq:NP_501067.1|wormbase:T22D1.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR042487|interpro:IPR037942|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027238|ensemblmetazoa:T22D1.10.1(transcript)|ensemblmetazoa:T22D1.10.2(transcript)|ensemblmetazoa:WBGene00020687(gene)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0097255"(R2TP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR041048 - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:dn+URkAlY1J22vwLn+hGlRujVis6239 - intact-crc:179A457A65523D02 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVU8 uniprotkb:Q22866-2 intact:EBI-2924098|ensemblmetazoa:W04D2.1b.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:q9xvu8_caeel(display_long)|uniprotkb:atn-1(gene name)|psi-mi:atn-1(display_short)|uniprotkb:W04D2.1(orf name)|uniprotkb:CELE_W04D2.1(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463849|imex:IM-11985-827 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:WBGene00000228(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0055120"(striated muscle dense body)|ensemblmetazoa:W04D2.1b.1(transcript)|refseq:NP_506128.1|wormbase:W04D2.1b|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|interpro:IPR036872 intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:zSgY77cAIMR1ffPvMFWTVk/BPiE6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:BC2D6242FC9692AF|rigid:1zwT3cs7w+nD85DAx6T6sn+qTkQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:O02482 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-314716|uniprotkb:P91912|ensemblmetazoa:W02D3.9.1|ensemblmetazoa:W02D3.9.2 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:unc37_caeel(display_long)|uniprotkb:unc-37(gene name)|psi-mi:unc-37(display_short)|uniprotkb:esg(gene name synonym)|uniprotkb:W02D3.9(orf name)|uniprotkb:Uncoordinated protein 37(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463830|imex:IM-11985-826 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) reactome:R-CEL-4641265|refseq:NP_491932.1|wormbase:W02D3.9|reactome:R-CEL-3769402|ensemblmetazoa:W02D3.9.1(transcript)|ensemblmetazoa:W02D3.9.2(transcript)|ensemblmetazoa:WBGene00006773(gene)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008134"(transcription factor binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|dip:DIP-27333N|reactome:R-CEL-201722 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:+e4X3QH+GChhuO2oAhaNGVwnO/o6239 intact-crc:2B1AD4ADB5BF93C3|rigid:SDuD0m/qCqkeE3Zjaa3K2Zjqfkc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5ECL3 uniprotkb:Q20763 intact:EBI-329618|ensemblmetazoa:W07E6.4.1 intact:EBI-2005534|ensemblmetazoa:F54D1.1.1 psi-mi:g5ecl3_caeel(display_long)|uniprotkb:prp-21(gene name)|psi-mi:prp-21(display_short)|uniprotkb:W07E6.4(orf name)|uniprotkb:Ceprp21(gene name synonym)|uniprotkb:CELE_W07E6.4(orf name) psi-mi:q20763_caeel(display_long)|uniprotkb:CELE_F54D1.1(orf name)|uniprotkb:F54D1.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463856|imex:IM-11985-828 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|refseq:NP_493746.1|uniprotkb:Q10577(uniprot-removed-ac)|reactome:R-CEL-72163|wormbase:W07E6.4|interpro:IPR029071|interpro:IPR035967|ensemblmetazoa:W07E6.4.1(transcript)|ensemblmetazoa:WBGene00004188(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR035563 refseq:NP_502114.1|wormbase:F54D1.1|interpro:IPR036612|ensemblmetazoa:F54D1.1.1(transcript)|ensemblmetazoa:WBGene00010046(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:OgSiSCeLk46Ctjas1LZExgzkL/c6239 rogid:BeQ1bUs/hwtdPfLgajBjyDrE8Mo6239 intact-crc:05894C7AB6A1C32D|rigid:AeS1IErP8n9F0XJFBBhkn/1sMvQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:Q9BL83 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-2005777|ensemblmetazoa:Y34D9A.10.1 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:q9bl83_caeel(display_long)|uniprotkb:vps-4(gene name)|psi-mi:vps-4(display_short)|uniprotkb:CELE_Y34D9A.10(orf name)|uniprotkb:Y34D9A.10(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463863|imex:IM-11985-829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) refseq:NP_490816.4|wormbase:Y34D9A.10|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR041569|interpro:IPR036181|reactome:R-CEL-9668328|interpro:IPR031255|ensemblmetazoa:WBGene00021334(gene)|ensemblmetazoa:Y34D9A.10.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007033"(vacuole organization)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0016197"(endosomal transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903539"(protein localization to postsynaptic membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:b93R1ndEtzzHaOF6Gv3G7NwLxAw6239 intact-crc:F8B91F0F00194764|rigid:rPSdA99bpkRgwvmxrl8PJ6xtN0I false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BKU4 uniprotkb:O45865 intact:EBI-2005861|ensemblmetazoa:Y37E3.9.1 intact:EBI-316202|ensemblmetazoa:T27E9.1a.1|ensemblmetazoa:T27E9.1a.2|ensemblmetazoa:T27E9.1a.3 psi-mi:phb1_caeel(display_long)|uniprotkb:phb-1(gene name)|psi-mi:phb-1(display_short)|uniprotkb:Y37E3.9(orf name) psi-mi:o45865_caeel(display_long)|uniprotkb:ant-1.1(gene name)|psi-mi:ant-1.1(display_short)|uniprotkb:ADP,ATP carrier protein(gene name synonym)|uniprotkb:CELE_T27E9.1(orf name)|uniprotkb:T27E9.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463870|imex:IM-11985-830 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490929.1|wormbase:Y37E3.9|interpro:IPR001107(Band 7 protein)|interpro:IPR000163(Prohibitin)|reactome:R-CEL-5673000|interpro:IPR036013|reactome:R-CEL-8949664|ensemblmetazoa:WBGene00004014(gene)|ensemblmetazoa:Y37E3.9.1(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030421"(defecation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0048477"(oogenesis)|go:"GO:0070584"(mitochondrion morphogenesis) refseq:NP_001022799.1|ensemblmetazoa:T27E9.1a.1(transcript)|ensemblmetazoa:T27E9.1a.2(transcript)|ensemblmetazoa:T27E9.1a.3(transcript)|ensemblmetazoa:WBGene00006439(gene)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|go:"GO:0043065"(positive regulation of apoptotic process)|wormbase:T27E9.1|dip:DIP-26385N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZbxYNRRXAY1g+BxP0Y2jH2JOQpQ6239 rogid:7/lerZIXX1DXrEd5fSuhrwT+Zmc6239 intact-crc:051FB99D95C14C16|rigid:yLntMAf1zTLEZbXOSuMcktL1uJs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BKU4 intact:EBI-2005873 intact:EBI-2005861|ensemblmetazoa:Y37E3.9.1 - psi-mi:phb1_caeel(display_long)|uniprotkb:phb-1(gene name)|psi-mi:phb-1(display_short)|uniprotkb:Y37E3.9(orf name) psi-mi:q86cz8_caeel(display_short)|psi-mi:EBI-2005873(display_long)|uniprotkb:ant-1.1(gene name)|psi-mi:ant-1.1(display_short)|uniprotkb:CELE_T27E9.1(orf name)|uniprotkb:T27E9.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463877|imex:IM-11985-831 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490929.1|wormbase:Y37E3.9|interpro:IPR001107(Band 7 protein)|interpro:IPR000163(Prohibitin)|reactome:R-CEL-5673000|interpro:IPR036013|reactome:R-CEL-8949664|ensemblmetazoa:WBGene00004014(gene)|ensemblmetazoa:Y37E3.9.1(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030421"(defecation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043051"(regulation of pharyngeal pumping)|go:"GO:0048477"(oogenesis)|go:"GO:0070584"(mitochondrion morphogenesis) uniprotkb:Q86CZ8(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZbxYNRRXAY1g+BxP0Y2jH2JOQpQ6239 rogid:Z1R/qmsLKfge2O5O4ZsHQbxb+qU6239 intact-crc:72EEEC99C9BA28B4|rigid:9fPGWcuedLWtoFYUp1I5od/QZfE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q965V4 uniprotkb:Q19749 intact:EBI-2005999|ensemblmetazoa:Y48G1A.5a.1 intact:EBI-320763|ensemblmetazoa:F23B12.5.1|ensemblmetazoa:F23B12.5.2 psi-mi:q965v4_caeel(display_long)|uniprotkb:xpo-2(gene name)|psi-mi:xpo-2(display_short)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:CELE_Y48G1A.5(orf name)|uniprotkb:Y48G1A.5(orf name) psi-mi:odp2_caeel(display_long)|uniprotkb:dlat-1(gene name)|psi-mi:dlat-1(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:F23B12.5(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463884|imex:IM-11985-832 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_490716.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR001494(Importin-beta, N-terminal)|wormbase:Y48G1A.5a|ensemblmetazoa:WBGene00002079(gene)|ensemblmetazoa:Y48G1A.5a.1(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding) refseq:NP_506579.1|wormbase:F23B12.5|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006096"(glycolytic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|ensemblmetazoa:F23B12.5.1(transcript)|ensemblmetazoa:F23B12.5.2(transcript)|ensemblmetazoa:WBGene00009082(gene)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|reactome:R-CEL-204174|reactome:R-CEL-5362517|reactome:R-CEL-70268|reactome:R-CEL-389661|dip:DIP-24773N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:y3TjuH8gOCN2TQZFkvYozdG2XXo6239 rogid:tRTfepPHk8sGJDuF9maWFsqI0No6239 intact-crc:CC9B948069B53359|rigid:6oQl2hyrmZuWiN0HVmkD+GyWug8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) intact:EBI-6463894 uniprotkb:Q95XY1 intact:EBI-6306360 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 psi-mi:ebi6306360(display_short)|psi-mi:EBI-6463894(display_long)|intact:F36A2.1b(author assigned name) psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463891|imex:IM-11985-833 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 psi-mi:"MI:0469"(intact) no-uniprot-update: - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 - rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 intact-crc:5D39270C04E18011 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:Q20711 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-327616|ensemblmetazoa:F53B3.6.1 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q20711_caeel(display_long)|uniprotkb:F53B3.6(orf name)|uniprotkb:CELE_F53B3.6(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463902|imex:IM-11985-834 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 refseq:NP_508496.1|wormbase:F53B3.6|ensemblmetazoa:F53B3.6.1(transcript)|ensemblmetazoa:WBGene00018744(gene)|dip:DIP-27015N psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:sAitHauLeui1eH7hdOP8EXyNG4s6239 intact-crc:10059D4FAD3E0E52|rigid:Seav72cjFS/z67wp82yq2Er71ng false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q95XY1 uniprotkb:Q22866-2 intact:EBI-331661|ensemblmetazoa:Y54E10A.9b.1|ensemblmetazoa:Y54E10A.9b.2|ensemblmetazoa:Y54E10A.9b.3 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:q95xy1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463909|imex:IM-11985-835 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_491112.1|wormbase:Y54E10A.9b|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9b.1(transcript)|ensemblmetazoa:Y54E10A.9b.2(transcript)|ensemblmetazoa:Y54E10A.9b.3(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|interpro:IPR044763 intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:W0Z3j5xT+pCk7ELJxEpkrG8cSM06239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:CF9F54DF2ABB7C0F|rigid:8tj551yqBd+doAVBGnG6lxmQEgo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 intact:EBI-6463894 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-6306360 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:ebi6306360(display_short)|psi-mi:EBI-6463894(display_long)|intact:F36A2.1b(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463916|imex:IM-11985-836 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 - intact-crc:F170C0148C3F8EC5 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20711 uniprotkb:Q65XX1 intact:EBI-327616|ensemblmetazoa:F53B3.6.1 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 psi-mi:q20711_caeel(display_long)|uniprotkb:F53B3.6(orf name)|uniprotkb:CELE_F53B3.6(orf name) psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463923|imex:IM-11985-837 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508496.1|wormbase:F53B3.6|ensemblmetazoa:F53B3.6.1(transcript)|ensemblmetazoa:WBGene00018744(gene)|dip:DIP-27015N refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:sAitHauLeui1eH7hdOP8EXyNG4s6239 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 intact-crc:BC4C7A5725E00086|rigid:RPmQXiVsPHhbSOqf9sAkOnHU9tk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q65XX1 uniprotkb:Q22866-2 intact:EBI-2004375|ensemblmetazoa:Y54E10A.9c.1|ensemblmetazoa:Y54E10A.9c.2 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:q65xx1_caeel(display_long)|uniprotkb:vbh-1(gene name)|psi-mi:vbh-1(display_short)|uniprotkb:CELE_Y54E10A.9(orf name)|uniprotkb:Y54E10A.9(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463930|imex:IM-11985-838 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021793.1|wormbase:Y54E10A.9c|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR044763|interpro:IPR027417|ensemblmetazoa:WBGene00006888(gene)|ensemblmetazoa:Y54E10A.9c.1(transcript)|ensemblmetazoa:Y54E10A.9c.2(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007276"(gamete generation)|go:"GO:0007281"(germ cell development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042006"(masculinization of hermaphroditic germ-line)|go:"GO:0043186"(P granule)|go:"GO:1905516"(positive regulation of fertilization) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:mlU+Z6sNrnQGtf+3+ytAINwGuI06239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:63D6B3C7A26572DB|rigid:InvXNeD3gDWjJRg1ilTLACqf9nQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XWK3 uniprotkb:Q22866-2 intact:EBI-324586|ensemblmetazoa:Y54E5A.4.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:q9xwk3_caeel(display_long)|uniprotkb:npp-4(gene name)|psi-mi:npp-4(display_short)|uniprotkb:Y54E5A.4(orf name)|uniprotkb:CELE_Y54E5A.4(orf name) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463937|imex:IM-11985-839 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493552.1|wormbase:Y54E5A.4|ensemblmetazoa:WBGene00003790(gene)|ensemblmetazoa:Y54E5A.4.1(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR025574|interpro:IPR026010|dip:DIP-25670N intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:gGD5J6YxTTCU1yObwsnAvF0pe486239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:ED4272B8FA5A1C71|rigid:ybSxzhGUr7fxQm9XJt6lbpzT3GE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N359 intact:EBI-6463944 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 intact:EBI-6306339 psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:ebi6306339(display_short)|psi-mi:EBI-6463944(display_long)|intact:C14F11.4a(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463948|imex:IM-11985-840 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 - intact-crc:EC1E280A7B0C3DA2 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N359 intact:EBI-6463955 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 intact:EBI-6306342 psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:ebi6306342(display_short)|psi-mi:EBI-6463955(display_long)|intact:C14F11.4b(author assigned name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463959|imex:IM-11985-841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 - psi-mi:"MI:0469"(intact) - no-uniprot-update: figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 - intact-crc:002E0EE9B3CC5FB0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9N359 uniprotkb:Q95PZ0 intact:EBI-331347|ensemblmetazoa:Y55F3AM.15.1 intact:EBI-314047|ensemblmetazoa:Y67H2A.6a.1 psi-mi:csn4_caeel(display_long)|uniprotkb:Y55F3AM.15(orf name)|uniprotkb:csn-4(gene name)|psi-mi:csn-4(display_short) psi-mi:csn6_caeel(display_long)|uniprotkb:Y67H2A.6(orf name)|uniprotkb:csn-6(gene name)|psi-mi:csn-6(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463966|imex:IM-11985-842 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_500034.1|wormbase:Y55F3AM.15|reactome:R-CEL-6781823|reactome:R-CEL-8951664|reactome:R-CEL-8856825|dip:DIP-27076N|ensemblmetazoa:WBGene00000816(gene)|ensemblmetazoa:Y55F3AM.15.1(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|go:"GO:0048477"(oogenesis)|interpro:IPR000717(Proteasome component region PCI)|reactome:R-CEL-5696394 refseq:NP_001255726.1|reactome:R-CEL-8951664|wormbase:Y67H2A.6a|ensemblmetazoa:WBGene00000818(gene)|ensemblmetazoa:Y67H2A.6a.1(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0048477"(oogenesis)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR037518|go:"GO:0008237"(metallopeptidase activity)|reactome:R-CEL-6781823|reactome:R-CEL-8856825|dip:DIP-27463N|reactome:R-CEL-5696394 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ggv0sNotAxIOJXPXLrSrejTpMHI6239 rogid:azXPU7X6plkNN9Z+JiU3z7YfVG86239 intact-crc:FB1864239F1AA564|rigid:Wz6jYBpm50tI3WYt+fhSupDIdiA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O61853 uniprotkb:Q2V0X4 intact:EBI-317974|ensemblmetazoa:F33E11.3.1 intact:EBI-6456854 psi-mi:o61853_caeel(display_long)|uniprotkb:CELE_F33E11.3(orf name)|uniprotkb:F33E11.3(orf name) psi-mi:q2v0x4_caeel(display_long)|uniprotkb:cogc-3(gene name)|psi-mi:cogc-3(display_short)|uniprotkb:Conserved oligomeric Golgi complex subunit 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463973|imex:IM-11985-843 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:O61853|interpro:IPR019343|refseq:NP_503171.1|wormbase:F33E11.3|ensemblmetazoa:F33E11.3.1(transcript)|ensemblmetazoa:WBGene00018011(gene)|interpro:IPR040024 go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|interpro:IPR007265(Sec34-like protein) psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:IANT//D+4A44krTSBSE1Nn19vLM6239 rogid:G/tGsp4WwyIUGdFnfOzoBMkgOrM6239 intact-crc:C5BD4524FE2FA7B2|rigid:hZtBUZ5IazyDVz8pVpJ9JbbQD4A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34605 uniprotkb:P34559 intact:EBI-312149|ensemblmetazoa:ZK1098.5.1 intact:EBI-329772|ensemblmetazoa:T05G5.6.1|ensemblmetazoa:T05G5.6.2 psi-mi:tppc3_caeel(display_long)|uniprotkb:trpp-3(gene name)|psi-mi:trpp-3(display_short)|uniprotkb:ZK1098.5(orf name) psi-mi:echm_caeel(display_long)|uniprotkb:T05G5.6(orf name)|uniprotkb:ech-6(gene name)|psi-mi:ech-6(display_short) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463980|imex:IM-11985-844 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_499100.1|wormbase:ZK1098.5|reactome:R-CEL-204005|ensemblmetazoa:WBGene00014222(gene)|ensemblmetazoa:ZK1098.5.1(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042338"(cuticle development involved in collagen and cuticulin-based cuticle molting cycle)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|reactome:R-CEL-8876198|dip:DIP-25615N reactome:R-CEL-70895|refseq:NP_499156.1|wormbase:T05G5.6|reactome:R-CEL-77310|dip:DIP-26850N|ensemblmetazoa:T05G5.6.1(transcript)|ensemblmetazoa:T05G5.6.2(transcript)|ensemblmetazoa:WBGene00001155(gene)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|reactome:R-CEL-77346|reactome:R-CEL-77348|reactome:R-CEL-77350|reactome:R-CEL-77352 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Nhf/6V5QuvCydW1gyu9tp4d8VQA6239 rogid:YI9W2EHH9wnNijR35cIE3uWkI3E6239 intact-crc:BB3D818B0B9C05B5|rigid:fT2ymEKaoQ8TDI5KU5fp4j6LBgY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34647-1 uniprotkb:Q22866-2 intact:EBI-6455889|ensemblmetazoa:ZK632.1a.1 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 psi-mi:p34647-1(display_long)|uniprotkb:ZK632.1(orf name)|uniprotkb:mcm-6(gene name)|psi-mi:mcm-6(display_short) psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463987|imex:IM-11985-845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2006759(isoform-parent)|ensemblmetazoa:WBGene00003158(gene)|ensemblmetazoa:ZK632.1a.1(transcript) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) psi-mi:"MI:0469"(intact) isoform-comment:No experimental confirmation available. - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:Bv0Zazm8QYFQ5nW05WKMSnLzHVs6239 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 intact-crc:02062157441B4289|rigid:LxKyDtZInOrxRVXJT7t20/6u94E false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22866-2 uniprotkb:Q09583 intact:EBI-329556|ensemblmetazoa:Y105E8B.1d.1 intact:EBI-315406|ensemblmetazoa:ZK945.2.1|ensemblmetazoa:ZK945.2.2 psi-mi:q22866-2(display_long)|uniprotkb:CeTM2(isoform synonym)|uniprotkb:CeTMII(isoform synonym)|uniprotkb:lev-11(gene name)|psi-mi:lev-11(display_short)|uniprotkb:tmy-1(gene name synonym)|uniprotkb:Levamisole resistant protein 11(gene name synonym)|uniprotkb:Y105E8B.1(orf name) psi-mi:psa3_caeel(display_long)|uniprotkb:pas-7(gene name)|psi-mi:pas-7(display_short)|uniprotkb:ZK945.2(orf name)|uniprotkb:Proteasome subunit alpha 7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Boxem et al. (2012) doi:10.1016/j.cell.2012.11.042|pubmed:unassigned701|imex:IM-11985|doi:"doi:10.1016/j.cell.2012.11.042" taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6463994|imex:IM-11985-846 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-329542(tpm1_caeel)|ensemblmetazoa:WBGene00002978(gene)|ensemblmetazoa:Y105E8B.1d.1(transcript) refseq:NP_496177.2|wormbase:ZK945.2|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-CEL-5632684|reactome:R-CEL-8932339|ensemblmetazoa:WBGene00003928(gene)|ensemblmetazoa:ZK945.2.1(transcript)|ensemblmetazoa:ZK945.2.2(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|interpro:IPR029055|reactome:R-CEL-5689603|reactome:R-CEL-5689880|reactome:R-CEL-68949|interpro:IPR037555|reactome:R-CEL-1234176|reactome:R-CEL-1236978|reactome:R-CEL-195253|reactome:R-CEL-349425|reactome:R-CEL-350562|reactome:R-CEL-382556|reactome:R-CEL-4608870|reactome:R-CEL-4641258|reactome:R-CEL-69017|reactome:R-CEL-69601|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8941858|reactome:R-CEL-8948751|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-5687128 psi-mi:"MI:0469"(intact) - - figure legend:Table S3 and additional information provided by the author|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/12/14 2014/10/16 rogid:ZTTnXzwYUlphBlaaNW2igArDi0k6239 rogid:OOdurA40PpJd/0X3BA8Z5ZWqCuM6239 intact-crc:9FDDC5939B9F4F3F|rigid:VFwYZiNOHWw1rLZuMPUWW1BGIIg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)