#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P07737 uniprotkb:Q92558 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 intact:EBI-1548747|uniprotkb:E1P5F2|uniprotkb:Q5SZK7|ensembl:ENSP00000352425|ensembl:ENSP00000376365|ensembl:ENSP00000376366|ensembl:ENSP00000376367|ensembl:ENSP00000376368 psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:wasf1_human(display_long)|uniprotkb:WASF1(gene name)|psi-mi:WASF1(display_short)|uniprotkb:KIAA0269(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:WAVE1(gene name synonym)|uniprotkb:Protein WAVE-1(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Miki et al. (1998) pubmed:9843499|imex:IM-18829 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6280383|imex:IM-18829-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N refseq:NP_001020105.1|refseq:NP_001020106.1|refseq:NP_001020107.1|refseq:NP_003922.1|refseq:XP_011534535.1|refseq:XP_011534536.1|refseq:XP_016866926.1|refseq:XP_016866927.1|refseq:XP_005267260.1|refseq:XP_005267262.1|refseq:XP_005267263.1|refseq:XP_005267264.1|dip:DIP-39391N|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000112290(gene)|ensembl:ENST00000359451(transcript)|ensembl:ENST00000392586(transcript)|ensembl:ENST00000392587(transcript)|ensembl:ENST00000392588(transcript)|ensembl:ENST00000392589(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031209"(SCAR complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098939"(dendritic transport of mitochondrion)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q92558|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149 - - - figure legend:"Fig 3A (lane 3), 3D, 6D."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/08/27 2014/10/16 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 rogid:kDHL44b54o8tE3+OR+M2CC6zi/k9606 intact-crc:DDDF22E62279FF7F|rigid:xVHlinw0Mhp5YaJyG7Jqtuyn938 false glutathione s tranferase tag:?-? necessary binding region:275-435|necessary binding region:498-513|myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P35080 uniprotkb:Q92558 intact:EBI-473138|uniprotkb:Q8WVF9|uniprotkb:Q9HBK2|uniprotkb:B2R4C8|uniprotkb:Q4VBQ4|uniprotkb:D3DNI4|ensembl:ENSP00000239940 intact:EBI-1548747|uniprotkb:E1P5F2|uniprotkb:Q5SZK7|ensembl:ENSP00000352425|ensembl:ENSP00000376365|ensembl:ENSP00000376366|ensembl:ENSP00000376367|ensembl:ENSP00000376368 psi-mi:prof2_human(display_long)|uniprotkb:PFN2(gene name)|psi-mi:PFN2(display_short)|uniprotkb:Profilin II(gene name synonym) psi-mi:wasf1_human(display_long)|uniprotkb:WASF1(gene name)|psi-mi:WASF1(display_short)|uniprotkb:KIAA0269(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:WAVE1(gene name synonym)|uniprotkb:Protein WAVE-1(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Miki et al. (1998) pubmed:9843499|imex:IM-18829 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6280391|imex:IM-18829-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002619.1|refseq:NP_444252.1|ensembl:ENSG00000070087(gene)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010633"(negative regulation of epithelial cell migration)|ensembl:ENST00000239940(transcript)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029891|interpro:IPR036140|mint:P35080|rcsb pdb:1D1J|reactome:R-HSA-376176|reactome:R-HSA-5663220 refseq:NP_001020105.1|refseq:NP_001020106.1|refseq:NP_001020107.1|refseq:NP_003922.1|refseq:XP_011534535.1|refseq:XP_011534536.1|refseq:XP_016866926.1|refseq:XP_016866927.1|refseq:XP_005267260.1|refseq:XP_005267262.1|refseq:XP_005267263.1|refseq:XP_005267264.1|dip:DIP-39391N|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000112290(gene)|ensembl:ENST00000359451(transcript)|ensembl:ENST00000392586(transcript)|ensembl:ENST00000392587(transcript)|ensembl:ENST00000392588(transcript)|ensembl:ENST00000392589(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031209"(SCAR complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098939"(dendritic transport of mitochondrion)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q92558|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149 - - - figure legend:"Fig 3A (lane 4)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/08/27 2014/10/16 rogid:064T9afVEb7WrgJPLVbKByJDUXc9606 rogid:kDHL44b54o8tE3+OR+M2CC6zi/k9606 intact-crc:13A11C636072C7A1|rigid:RQdPFevVCNhORANtc4ThE9ocRT0 false glutathione s tranferase tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P07737 uniprotkb:Q92558 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 intact:EBI-1548747|uniprotkb:E1P5F2|uniprotkb:Q5SZK7|ensembl:ENSP00000352425|ensembl:ENSP00000376365|ensembl:ENSP00000376366|ensembl:ENSP00000376367|ensembl:ENSP00000376368 psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:wasf1_human(display_long)|uniprotkb:WASF1(gene name)|psi-mi:WASF1(display_short)|uniprotkb:KIAA0269(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:WAVE1(gene name synonym)|uniprotkb:Protein WAVE-1(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 1(gene name synonym) psi-mi:"MI:0047"(far western blotting) Miki et al. (1998) pubmed:9843499|imex:IM-18829 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6280407|imex:IM-18829-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N refseq:NP_001020105.1|refseq:NP_001020106.1|refseq:NP_001020107.1|refseq:NP_003922.1|refseq:XP_011534535.1|refseq:XP_011534536.1|refseq:XP_016866926.1|refseq:XP_016866927.1|refseq:XP_005267260.1|refseq:XP_005267262.1|refseq:XP_005267263.1|refseq:XP_005267264.1|dip:DIP-39391N|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000112290(gene)|ensembl:ENST00000359451(transcript)|ensembl:ENST00000392586(transcript)|ensembl:ENST00000392587(transcript)|ensembl:ENST00000392588(transcript)|ensembl:ENST00000392589(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031209"(SCAR complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098939"(dendritic transport of mitochondrion)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q92558|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149 - - - figure legend:Fig 3B.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/08/27 2014/10/16 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 rogid:kDHL44b54o8tE3+OR+M2CC6zi/k9606 intact-crc:B3E20CB4575A37FD|rigid:xVHlinw0Mhp5YaJyG7Jqtuyn938 false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P68139 uniprotkb:Q92558 intact:EBI-3058728|ensembl:ENSGALP00000060685|uniprotkb:P02568|uniprotkb:P99020 intact:EBI-1548747|uniprotkb:E1P5F2|uniprotkb:Q5SZK7|ensembl:ENSP00000352425|ensembl:ENSP00000376365|ensembl:ENSP00000376366|ensembl:ENSP00000376367|ensembl:ENSP00000376368 psi-mi:acts_chick(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:wasf1_human(display_long)|uniprotkb:WASF1(gene name)|psi-mi:WASF1(display_short)|uniprotkb:KIAA0269(gene name synonym)|uniprotkb:SCAR1(gene name synonym)|uniprotkb:WAVE1(gene name synonym)|uniprotkb:Protein WAVE-1(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Miki et al. (1998) pubmed:9843499|imex:IM-18829 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:1222"(mbinfo) intact:EBI-6280616|imex:IM-18829-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7BTI|rcsb pdb:7K20|rcsb pdb:7K21|rcsb pdb:7KCH|rcsb pdb:6D8C|rcsb pdb:6DJM|rcsb pdb:6DJN|rcsb pdb:6DJO|rcsb pdb:6M5G|rcsb pdb:6UPV|rcsb pdb:6UPW|rcsb pdb:6X5Z|rcsb pdb:7BT7|rcsb pdb:7BTE|ensembl:ENSGALG00000011086(gene)|ensembl:ENSGALT00000088724(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005524"(ATP binding)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0048741"(skeletal muscle fiber development)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1MDU|rcsb pdb:5YU8|refseq:NP_001026234.1|dip:DIP-41824N|refseq:XP_015139542.1 refseq:NP_001020105.1|refseq:NP_001020106.1|refseq:NP_001020107.1|refseq:NP_003922.1|refseq:XP_011534535.1|refseq:XP_011534536.1|refseq:XP_016866926.1|refseq:XP_016866927.1|refseq:XP_005267260.1|refseq:XP_005267262.1|refseq:XP_005267263.1|refseq:XP_005267264.1|dip:DIP-39391N|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000112290(gene)|ensembl:ENST00000359451(transcript)|ensembl:ENST00000392586(transcript)|ensembl:ENST00000392587(transcript)|ensembl:ENST00000392588(transcript)|ensembl:ENST00000392589(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031209"(SCAR complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098939"(dendritic transport of mitochondrion)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q92558|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149 - - - figure legend:Fig 6A, 6C.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/08/27 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49031 rogid:kDHL44b54o8tE3+OR+M2CC6zi/k9606 intact-crc:01FAFBA2BCDCEB86|rigid:LWXmyG38JK6H/EFvcYW7hviPuRI false - necessary binding region:498-513|sufficient binding region:?-?|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)