#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06710	uniprotkb:P28630	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453526|imex:IM-18534-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	-	-	crc64:87239A678FE16BE2	figure legend:Fig. 5c, 6a|complex-properties:"Gamma complex of DNA polymerase made up of 5 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in gamma complex (see Fig.s 5d & e for lack of interaction if HolC is missing from mixture).   Gamma complex only binds to ssDNA when SSB is present (see Fig. 6b). Gamma complex-SSB does not bing to dsDNA (see Fig.6c)."|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	intact-crc:4D1A694086C68FF7	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06710	uniprotkb:P28631	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453526|imex:IM-18534-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	-	-	-	figure legend:Fig. 5c, 6a|complex-properties:"Gamma complex of DNA polymerase made up of 5 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in gamma complex (see Fig.s 5d & e for lack of interaction if HolC is missing from mixture).   Gamma complex only binds to ssDNA when SSB is present (see Fig. 6b). Gamma complex-SSB does not bing to dsDNA (see Fig.6c)."|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	intact-crc:4D1A694086C68FF7	false	-	3h radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06710	uniprotkb:P28905	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453526|imex:IM-18534-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	figure legend:Fig. 5c, 6a|complex-properties:"Gamma complex of DNA polymerase made up of 5 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in gamma complex (see Fig.s 5d & e for lack of interaction if HolC is missing from mixture).   Gamma complex only binds to ssDNA when SSB is present (see Fig. 6b). Gamma complex-SSB does not bing to dsDNA (see Fig.6c)."|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:4D1A694086C68FF7	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06710	uniprotkb:P28632	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453526|imex:IM-18534-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU	-	-	-	figure legend:Fig. 5c, 6a|complex-properties:"Gamma complex of DNA polymerase made up of 5 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in gamma complex (see Fig.s 5d & e for lack of interaction if HolC is missing from mixture).   Gamma complex only binds to ssDNA when SSB is present (see Fig. 6b). Gamma complex-SSB does not bing to dsDNA (see Fig.6c)."|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333	intact-crc:4D1A694086C68FF7	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06710	intact:EBI-6389588	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	-	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:m13mp18(display_short)|psi-mi:EBI-6389588(display_long)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453526|imex:IM-18534-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	ddbj/embl/genbank:x02513	-	-	-	figure legend:Fig. 5c, 6a|complex-properties:"Gamma complex of DNA polymerase made up of 5 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in gamma complex (see Fig.s 5d & e for lack of interaction if HolC is missing from mixture).   Gamma complex only binds to ssDNA when SSB is present (see Fig. 6b). Gamma complex-SSB does not bing to dsDNA (see Fig.6c)."|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	-	intact-crc:4D1A694086C68FF7	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06710	uniprotkb:P0AGE0	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453526|imex:IM-18534-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	figure legend:Fig. 5c, 6a|complex-properties:"Gamma complex of DNA polymerase made up of 5 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in gamma complex (see Fig.s 5d & e for lack of interaction if HolC is missing from mixture).   Gamma complex only binds to ssDNA when SSB is present (see Fig. 6b). Gamma complex-SSB does not bing to dsDNA (see Fig.6c)."|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:4D1A694086C68FF7	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P28905	-	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453582|imex:IM-18534-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	figure legend:Fig. 7c|comment:"oligo(dT65) was used"|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:53.0x10^-9(molar)	2012/12/13	2014/10/16	-	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:5AB443FF2BFC6397	false	-	3h radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453582|imex:IM-18534-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	figure legend:Fig. 7c|comment:"oligo(dT65) was used"|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:53.0x10^-9(molar)	2012/12/13	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:5AB443FF2BFC6397	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P0A988	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-542385|uniprotkb:P00583|uniprotkb:Q2M813|ensemblbacteria:AAC76724|ensemblbacteria:BAE77593	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:dpo3b_ecoli(display_long)|uniprotkb:dnaN(gene name)|psi-mi:dnaN(display_short)|uniprotkb:Beta-clamp processivity factor(gene name synonym)|uniprotkb:DNA polymerase III beta sliding clamp subunit(gene name synonym)|uniprotkb:JW3678(locus name)|uniprotkb:b3701(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	ensemblbacteria:AAC76724(transcript)|ensemblbacteria:b3701(gene)|ensemblbacteria:BAE77593(gene)|ensemblbacteria:BAE77593(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0044787"(bacterial-type DNA replication)|interpro:IPR001001(DNA polymerase III, beta chain)|interpro:IPR022634|interpro:IPR022635|interpro:IPR022637|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1MMI|rcsb pdb:1OK7|rcsb pdb:1UNN|rcsb pdb:1WAI|rcsb pdb:2POL|rcsb pdb:2XUR|rcsb pdb:3BEP|rcsb pdb:3D1E|rcsb pdb:3D1F|rcsb pdb:3D1G|rcsb pdb:3F1V|rcsb pdb:3PWE|rcsb pdb:3Q4J|rcsb pdb:3Q4K|rcsb pdb:3Q4L|rcsb pdb:3QSB|rcsb pdb:4K3K|rcsb pdb:4K3L|rcsb pdb:4K3M|rcsb pdb:4K3O|rcsb pdb:4K3P|rcsb pdb:4K3Q|rcsb pdb:4K3R|rcsb pdb:4K3S|rcsb pdb:4MJP|rcsb pdb:4MJQ|rcsb pdb:4MJR|rcsb pdb:4N94|rcsb pdb:4N95|rcsb pdb:4N96|rcsb pdb:4N97|rcsb pdb:4N98|rcsb pdb:4N99|rcsb pdb:4N9A|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:6E8E|rcsb pdb:6FVL|refseq:NP_418156.1|refseq:WP_000673464.1|dip:DIP-36038N	-	-	caution:This sequence has been withdrawn from Uniprot.	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:9CWZmgLmO/kNXmVq75u0u04mX2g83333	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P03007	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549131|ensemblbacteria:AAC73320|ensemblbacteria:BAA77886	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:dpo3e_ecoli(display_long)|uniprotkb:dnaQ(gene name)|psi-mi:dnaQ(display_short)|uniprotkb:mutD(gene name synonym)|uniprotkb:b0215(locus name)|uniprotkb:JW0205(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_414751.1|refseq:WP_001340895.1|dip:DIP-9462N|ensemblbacteria:AAC73320(transcript)|ensemblbacteria:b0215(gene)|ensemblbacteria:BAA77886(gene)|ensemblbacteria:BAA77886(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005829"(cytosol)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|interpro:IPR006054(DNA polymerase III, epsilon subunit)|interpro:IPR006309(DNA polymerase 3, epsilon subunit)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036397|rcsb pdb:1J53|rcsb pdb:1J54|rcsb pdb:1MGZ|rcsb pdb:2GUI|rcsb pdb:2IDO|rcsb pdb:2XY8|rcsb pdb:4GX8|rcsb pdb:4GX9|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S	-	-	-	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:+Xs56/RcG3EYpWsa57MFJRFspoI83333	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P06710	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	-	-	-	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P28630	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549153|ensemblbacteria:AAC73741|ensemblbacteria:BAA35287	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:hola_ecoli(display_long)|uniprotkb:b0640(locus name)|uniprotkb:holA(gene name)|psi-mi:holA(display_short)|uniprotkb:JW0635(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_415173.1|refseq:WP_000620535.1|dip:DIP-9931N|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|ensemblbacteria:AAC73741(transcript)|ensemblbacteria:b0640(gene)|ensemblbacteria:BAA35287(gene)|ensemblbacteria:BAA35287(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR005790(DNA polymerase III, delta subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR010372(DNA polymerase III, delta)|interpro:IPR027417|interpro:IPR032780|rcsb pdb:1JQJ|rcsb pdb:1JQL|rcsb pdb:1JR3|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:3GLF	-	-	crc64:87239A678FE16BE2	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:xMcC78PZeDNSqwRnRtbA31N1xMg83333	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P28631	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549161|ensemblbacteria:BAA35906|ensemblbacteria:AAC74183	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:holb_ecoli(display_long)|uniprotkb:holB(gene name)|psi-mi:holB(display_short)|uniprotkb:b1099(locus name)|uniprotkb:JW1085(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_415617.1|refseq:WP_001267956.1|dip:DIP-9932N|ensemblbacteria:BAA35906(gene)|ensemblbacteria:BAA35906(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009360"(DNA polymerase III complex)|interpro:IPR004622(DNA polymerase III, delta prime subunit)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR015199(DNA polymerase III, delta subunit, C-terminal)|interpro:IPR027417|rcsb pdb:1A5T|rcsb pdb:1JR3|rcsb pdb:1XXH|ensemblbacteria:AAC74183(transcript)|ensemblbacteria:b1099(gene)|rcsb pdb:1XXI|rcsb pdb:3GLF|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:3GLG	-	-	-	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:Wd7zI2kwfKLoHTrbfM9l98atQuw83333	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P28905	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P28632	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU	-	-	-	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P0ABS8	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549182|uniprotkb:P28689|ensemblbacteria:AAC74912|ensemblbacteria:BAA15650	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:hole_ecoli(display_long)|uniprotkb:holE(gene name)|psi-mi:holE(display_short)|uniprotkb:b1842(locus name)|uniprotkb:JW1831(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_416356.1|refseq:WP_000916763.1|dip:DIP-39982N|ensemblbacteria:AAC74912(transcript)|ensemblbacteria:b1842(gene)|ensemblbacteria:BAA15650(gene)|ensemblbacteria:BAA15650(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|interpro:IPR009052(DNA polymerase III-theta, bacterial)|interpro:IPR036745|rcsb pdb:1DU2|rcsb pdb:2AE9|rcsb pdb:2AXD|rcsb pdb:2XY8|rcsb pdb:5M1S	-	-	crc64:3667D87327E96556	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:SxpHzzC2294kTc9GlPUQNoxa9AU83333	intact-crc:8DE1DDA10EB9B2BA	false	-	3h radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	intact:EBI-6389588	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	-	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:m13mp18(display_short)|psi-mi:EBI-6389588(display_long)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0680"(single stranded deoxyribonucleic acid)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	ddbj/embl/genbank:x02513	-	-	-	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	-	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P0AGE0	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453429|imex:IM-18534-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	figure legend:Fig. 5a|complex-properties:"DNA Polymerase III Complex made up of 10 subunits and tetrameric single-stranded binding protein (coated on single-stranded DNA) interact only if subunit chi (HolC) is present in Polymerase complex (see Fig. 5b for lack of interaction of HolC if missing from mixture)"|complex-synonym:DNA Polymerase III Complex = DNA Pol III complex  single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:8DE1DDA10EB9B2BA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-6453234	uniprotkb:P28905	-	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:87mer-dna(display_short)|psi-mi:EBI-6453234(display_long)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453568|imex:IM-18534-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	figure legend:Fig. 7b|comment:"Gamma and SSB also interact in the presence of oligo(dT65) and oligo(dT35)."|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	-	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:01BE02A0BA947D93	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-6453234	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:87mer-dna(display_short)|psi-mi:EBI-6453234(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0071"(molecular sieving)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453568|imex:IM-18534-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	figure legend:Fig. 7b|comment:"Gamma and SSB also interact in the presence of oligo(dT65) and oligo(dT35)."|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:01BE02A0BA947D93	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P28905	-	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6455078|imex:IM-18534-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	figure legend:Fig. 11a, b|comment:"oligo(dT100) was used  A stoichiometry of 1:1 was calculated for the interaction of these two units, this ratio is not maintained in the macromolecular complex!  SSB-113, which carries a Ser113Pro substitution, does not bind gamma (see Fig. 11a, c)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:330.0x10^-9(molar)	2012/12/13	2014/10/16	-	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:ABDCE9198EBF8772	false	-	sufficient binding region:100-114	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6455078|imex:IM-18534-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	figure legend:Fig. 11a, b|comment:"oligo(dT100) was used  A stoichiometry of 1:1 was calculated for the interaction of these two units, this ratio is not maintained in the macromolecular complex!  SSB-113, which carries a Ser113Pro substitution, does not bind gamma (see Fig. 11a, c)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:330.0x10^-9(molar)	2012/12/13	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:ABDCE9198EBF8772	false	-	-	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28905	uniprotkb:P0AGE0	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453612|imex:IM-18534-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	crc64:7FEFFC359B28AA88	-	figure legend:Fig. 8b|complex-properties:Gamma binds directly to SSB.|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:53.0x10^-9(molar)	2012/12/13	2014/10/16	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:169927FA133B40BB|rigid:NfLDt43Dzi1f+era/3o87/dHPU4	false	-	-	2	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P0AGE0	-	intact:EBI-1118620|uniprotkb:P02339|uniprotkb:Q2M6P5|ensemblbacteria:AAC77029|ensemblbacteria:BAE78061	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:ssb_ecoli(display_long)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:ssb(gene name)|psi-mi:ssb(display_short)|uniprotkb:exrB(gene name synonym)|uniprotkb:lexC(gene name synonym)|uniprotkb:b4059(locus name)|uniprotkb:JW4020(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453593|imex:IM-18534-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblbacteria:AAC77029(transcript)|ensemblbacteria:b4059(gene)|ensemblbacteria:BAE78061(gene)|ensemblbacteria:BAE78061(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006298"(mismatch repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|go:"GO:0009295"(nucleoid)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1EQQ|rcsb pdb:1EYG|rcsb pdb:1KAW|rcsb pdb:1QVC|rcsb pdb:1SRU|rcsb pdb:3C94|rcsb pdb:3SXU|rcsb pdb:3UF7|rcsb pdb:4MZ9|rcsb pdb:4Z0U|refseq:NP_418483.1|refseq:WP_000168305.1|dip:DIP-35980N	-	-	-	figure legend:Fig. 8a|comment:"oligo(dT65) was used  A stoichiometry of 1:1 was calculated for the interaction of these two units, this ratio is not maintained in the macromolecular complex!  Gamma does not bind directly to ssDNA (see Fig. 8c)"|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	-	rogid:6jbUAKl9DZz/5bpQhcIh1TtNTJI83333	intact-crc:D2AB346E1D53EC42	false	-	-	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-3953546	uniprotkb:P28905	-	intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256	psi-mi:dt-dna(display_short)|psi-mi:EBI-3953546(display_long)	psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Kelman et al. (1998)	pubmed:9545254|imex:IM-18534	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6453593|imex:IM-18534-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU	-	-	crc64:7FEFFC359B28AA88	figure legend:Fig. 8a|comment:"oligo(dT65) was used  A stoichiometry of 1:1 was calculated for the interaction of these two units, this ratio is not maintained in the macromolecular complex!  Gamma does not bind directly to ssDNA (see Fig. 8c)"|complex-synonym:single-stranded binding protein = SSB|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/13	2014/10/16	-	rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333	intact-crc:D2AB346E1D53EC42	false	-	-	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)