#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12003	uniprotkb:P50552	intact:EBI-1039563|uniprotkb:Q91024|ensembl:ENSGALP00000008131	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932	psi-mi:vinc_chick(display_long)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)|uniprotkb:VINC1(gene name synonym)|uniprotkb:Metavinculin(gene name synonym)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	psi-mi:"MI:0096"(pull down)	Brindle et al. (1996)	pubmed:8836115|imex:IM-16843	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-5486022|imex:IM-16843-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015143689.1|refseq:NP_990772.1|ensembl:ENSGALG00000005079(gene)|ensembl:ENSGALT00000008145(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|rcsb pdb:1QKR|rcsb pdb:1ST6|rcsb pdb:1T01|rcsb pdb:1U6H|rcsb pdb:1XWJ|rcsb pdb:1ZVZ|rcsb pdb:1ZW2|rcsb pdb:1ZW3|rcsb pdb:2GDC|rcsb pdb:3JBI|rcsb pdb:3ZDL|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:6FQ4|rcsb pdb:6NR7|reactome:R-GGA-114608|reactome:R-GGA-445355|reactome:R-GGA-5674135|reactome:R-GGA-6798695|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P12003|dip:DIP-35191N	refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N	-	-	-	figure legend:Fig. 2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/10	2014/10/16	rogid:94z6CivjYryFIKVVE4dRTbssflA9031	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:C934EEDB1E32BAE4|rigid:b8XXqaO98d9LEdi1hAOcRQTGnXU	false	sufficient binding region:836-940|glutathione s tranferase tag:n-n	3h radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P50552	uniprotkb:P12003	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932	intact:EBI-1039563|uniprotkb:Q91024|ensembl:ENSGALP00000008131	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	psi-mi:vinc_chick(display_long)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)|uniprotkb:VINC1(gene name synonym)|uniprotkb:Metavinculin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Brindle et al. (1996)	pubmed:8836115|imex:IM-16843	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-5525632|imex:IM-16843-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N	refseq:XP_015143689.1|refseq:NP_990772.1|ensembl:ENSGALG00000005079(gene)|ensembl:ENSGALT00000008145(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0005927"(muscle tendon junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|rcsb pdb:1QKR|rcsb pdb:1ST6|rcsb pdb:1T01|rcsb pdb:1U6H|rcsb pdb:1XWJ|rcsb pdb:1ZVZ|rcsb pdb:1ZW2|rcsb pdb:1ZW3|rcsb pdb:2GDC|rcsb pdb:3JBI|rcsb pdb:3ZDL|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:6FQ4|rcsb pdb:6NR7|reactome:R-GGA-114608|reactome:R-GGA-445355|reactome:R-GGA-5674135|reactome:R-GGA-6798695|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P12003|dip:DIP-35191N	-	-	-	figure legend:Fig. 3, 4b and 5.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/10	2014/10/16	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	rogid:94z6CivjYryFIKVVE4dRTbssflA9031	intact-crc:20B88BAE86A6DA9D|rigid:b8XXqaO98d9LEdi1hAOcRQTGnXU	false	3h radiolabel:?-?|necessary binding region:326-380	sufficient binding region:839-850	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P00516	uniprotkb:P50552	intact:EBI-5525781|uniprotkb:P21136|ensembl:ENSBTAP00000024490	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932	psi-mi:kgp1_bovin(display_long)|uniprotkb:PRKG1(gene name)|psi-mi:PRKG1(display_short)|uniprotkb:PRKG1B(gene name synonym)|uniprotkb:PRKGR1A(gene name synonym)|uniprotkb:PRKGR1B(gene name synonym)|uniprotkb:cGMP-dependent protein kinase I(gene name synonym)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Brindle et al. (1996)	pubmed:8836115|imex:IM-16843	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-5525780|imex:IM-16843-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59143N|refseq:NP_776861.1|refseq:XP_005225410.1|ensembl:ENSBTAG00000018404(gene)|ensembl:ENSBTAT00000024490(transcript)|go:"GO:0004692"(cGMP-dependent protein kinase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030553"(cGMP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002374(cGMP-dependent protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018488|interpro:IPR018490|interpro:IPR031831|interpro:IPR035014|rcsb pdb:3SHR|reactome:R-BTA-392517	refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/10	2014/10/16	rogid:B9ahkgNZP+yGxincOw5SKBoYaKs9913	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:5465706C540EC291|rigid:yNWnMDLrIrUI8h0p4GyeJhkO3OI	false	-	3h radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P36887	uniprotkb:P50552	intact:EBI-5525961	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932	psi-mi:kapca_pig(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	psi-mi:"MI:0424"(protein kinase assay)	Brindle et al. (1996)	pubmed:8836115|imex:IM-16843	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-5525949|imex:IM-16843-4	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR044109|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:1CDK|rcsb pdb:1CMK|rcsb pdb:1CTP|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042585"(germinal vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904145"(negative regulation of meiotic cell cycle process involved in oocyte maturation)	refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	isoform-comment:Porcine cAMP-dependent protein kinase has two catalytic subunits- alpha and beta. This entry involves catalytic subunit alpha.|figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/10	2014/10/16	rogid:smyU6cXzLh1tzpnXtP8tr+8wuZI9823	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:9C5FBBDDC2F0116A|rigid:sSHhLuElHAB+OnvoXvyUDuohhJM	false	-	3h radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P67774	uniprotkb:P50552	intact:EBI-5525987|uniprotkb:A6QLI7|uniprotkb:P05323|uniprotkb:P13197|ensembl:ENSBTAP00000000596	intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932	psi-mi:pp2aa_bovin(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)	psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short)	psi-mi:"MI:1019"(protein phosphatase assay)	Brindle et al. (1996)	pubmed:8836115|imex:IM-16843	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:1222"(mbinfo)	intact:EBI-5529366|imex:IM-16843-5	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_851374.1|ensembl:ENSBTAG00000000469(gene)|ensembl:ENSBTAT00000000596(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67774|reactome:R-BTA-1295596|reactome:R-BTA-195253|reactome:R-BTA-196299|reactome:R-BTA-198753|reactome:R-BTA-202670|reactome:R-BTA-389513|reactome:R-BTA-432142|reactome:R-BTA-5673000|reactome:R-BTA-5675221	refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N	go:"GO:0006470"(protein dephosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)	-	-	figure legend:Fig. 4b.|isoform-comment:Bovine protein phosphatase 2A has two catalytic subunits-alpha and beta. The subunit included in this entry is catalytic subunit alpha.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/10	2014/10/16	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9913	rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606	intact-crc:30185CEF6D4F9AC3|rigid:rR6v/mzVMYTcEWq3HOxy6kr9hs8	false	-	3h radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)