#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q07021	uniprotkb:P01042	intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698	intact:EBI-6378713|ensembl:ENSP00000493985|uniprotkb:C9JEX1|uniprotkb:A8K474|uniprotkb:B2RCR2|uniprotkb:P01043|uniprotkb:Q53EQ0|uniprotkb:Q6PAU9|uniprotkb:Q7M4P1	psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym)	psi-mi:kng1_human(display_long)|uniprotkb:KNG1(gene name)|psi-mi:KNG1(display_short)|uniprotkb:BDK(gene name synonym)|uniprotkb:KNG(gene name synonym)|uniprotkb:Alpha-2-thiol proteinase inhibitor(gene name synonym)|uniprotkb:Fitzgerald factor(gene name synonym)|uniprotkb:High molecular weight kininogen(gene name synonym)|uniprotkb:Williams-Fitzgerald-Flaujeac factor(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Joseph et al. (1996)	pubmed:8710908|imex:IM-20572	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6378711|imex:IM-20572-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837	ensembl:ENSG00000113889(gene)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENST00000644859(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042311"(vasodilation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR002395(HMW kininogen)|interpro:IPR018073|interpro:IPR027358|mint:P01042|rcsb pdb:1NY2|rcsb pdb:2WOK|rcsb pdb:4ASQ|rcsb pdb:4ASR|rcsb pdb:4ECB|rcsb pdb:4ECC|rcsb pdb:5I25|rcsb pdb:6F27|rcsb pdb:6F3V|rcsb pdb:6F3W|rcsb pdb:6F3X|rcsb pdb:6F3Y|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-375276|reactome:R-HSA-381426|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-8957275|go:"GO:0005615"(extracellular space)|refseq:NP_000884.1|refseq:NP_001095886.1|refseq:NP_001159923.1	-	-	-	figure legend:3A and B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/10/31	2016/03/07	rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606	rogid:Z/DOKINto4Ygn9lYUu6nuHA3soM9606	intact-crc:6EFFE79AFFBEE4A3|rigid:ziitW9p3HGSZtH+w6rgxolnrn/A	false	-	-	-	-	psi-mi:"MI:0433"(partial identification of protein sequence)	psi-mi:"MI:0433"(partial identification of protein sequence)
uniprotkb:P01042	uniprotkb:Q07021	intact:EBI-6378713|ensembl:ENSP00000493985|uniprotkb:C9JEX1|uniprotkb:A8K474|uniprotkb:B2RCR2|uniprotkb:P01043|uniprotkb:Q53EQ0|uniprotkb:Q6PAU9|uniprotkb:Q7M4P1	intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698	psi-mi:kng1_human(display_long)|uniprotkb:KNG1(gene name)|psi-mi:KNG1(display_short)|uniprotkb:BDK(gene name synonym)|uniprotkb:KNG(gene name synonym)|uniprotkb:Alpha-2-thiol proteinase inhibitor(gene name synonym)|uniprotkb:Fitzgerald factor(gene name synonym)|uniprotkb:High molecular weight kininogen(gene name synonym)|uniprotkb:Williams-Fitzgerald-Flaujeac factor(gene name synonym)	psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Joseph et al. (1996)	pubmed:8710908|imex:IM-20572	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6378770|imex:IM-20572-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113889(gene)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENST00000644859(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042311"(vasodilation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR002395(HMW kininogen)|interpro:IPR018073|interpro:IPR027358|mint:P01042|rcsb pdb:1NY2|rcsb pdb:2WOK|rcsb pdb:4ASQ|rcsb pdb:4ASR|rcsb pdb:4ECB|rcsb pdb:4ECC|rcsb pdb:5I25|rcsb pdb:6F27|rcsb pdb:6F3V|rcsb pdb:6F3W|rcsb pdb:6F3X|rcsb pdb:6F3Y|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-375276|reactome:R-HSA-381426|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-8957275|go:"GO:0005615"(extracellular space)|refseq:NP_000884.1|refseq:NP_001095886.1|refseq:NP_001159923.1	refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837	-	-	-	figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/10/31	2016/03/07	rogid:Z/DOKINto4Ygn9lYUu6nuHA3soM9606	rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606	intact-crc:F605B8369EB5C3F2|rigid:ziitW9p3HGSZtH+w6rgxolnrn/A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q07021	uniprotkb:P00748	intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698	intact:EBI-6378830|ensembl:ENSP00000253496|uniprotkb:P78339	psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym)	psi-mi:fa12_human(display_long)|uniprotkb:F12(gene name)|psi-mi:F12(display_short)|uniprotkb:Hageman factor(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Joseph et al. (1996)	pubmed:8710908|imex:IM-20572	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6389263|imex:IM-20572-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837	ensembl:ENSG00000131187(gene)|ensembl:ENST00000253496(transcript)|go:"GO:0002353"(plasma kallikrein-kinin cascade)|go:"GO:0002542"(Factor XII activation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045087"(innate immune response)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:4BDW|rcsb pdb:4BDX|rcsb pdb:4XDE|rcsb pdb:4XE4|rcsb pdb:6B74|rcsb pdb:6B77|rcsb pdb:6GT6|rcsb pdb:6L63|rcsb pdb:6QF7|rcsb pdb:6SZW|rcsb pdb:6X0S|rcsb pdb:6X0T|reactome:R-HSA-140837|reactome:R-HSA-9657688|reactome:R-HSA-9657689|refseq:NP_000496.2	-	-	-	figure legend:"4B (6)"|agonist:zinc|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/10/31	2016/03/07	rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606	rogid:zthfDMI8e+gVU6iCWUMwKKEGbqA9606	intact-crc:E8BE97548687ABB4|rigid:NMaRVVOSNOp+M1azdONmwHUjqvo	false	-	biotin tag:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q07021	uniprotkb:P01042	intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698	intact:EBI-6378713|ensembl:ENSP00000493985|uniprotkb:C9JEX1|uniprotkb:A8K474|uniprotkb:B2RCR2|uniprotkb:P01043|uniprotkb:Q53EQ0|uniprotkb:Q6PAU9|uniprotkb:Q7M4P1	psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym)	psi-mi:kng1_human(display_long)|uniprotkb:KNG1(gene name)|psi-mi:KNG1(display_short)|uniprotkb:BDK(gene name synonym)|uniprotkb:KNG(gene name synonym)|uniprotkb:Alpha-2-thiol proteinase inhibitor(gene name synonym)|uniprotkb:Fitzgerald factor(gene name synonym)|uniprotkb:High molecular weight kininogen(gene name synonym)|uniprotkb:Williams-Fitzgerald-Flaujeac factor(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Joseph et al. (1996)	pubmed:8710908|imex:IM-20572	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6378884|imex:IM-20572-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837	ensembl:ENSG00000113889(gene)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENST00000644859(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042311"(vasodilation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR002395(HMW kininogen)|interpro:IPR018073|interpro:IPR027358|mint:P01042|rcsb pdb:1NY2|rcsb pdb:2WOK|rcsb pdb:4ASQ|rcsb pdb:4ASR|rcsb pdb:4ECB|rcsb pdb:4ECC|rcsb pdb:5I25|rcsb pdb:6F27|rcsb pdb:6F3V|rcsb pdb:6F3W|rcsb pdb:6F3X|rcsb pdb:6F3Y|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-375276|reactome:R-HSA-381426|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-8957275|go:"GO:0005615"(extracellular space)|refseq:NP_000884.1|refseq:NP_001095886.1|refseq:NP_001159923.1	-	-	-	figure legend:"4A (2)"|agonist:zinc|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/10/31	2016/03/07	rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606	rogid:Z/DOKINto4Ygn9lYUu6nuHA3soM9606	intact-crc:77AC78451BA0B5F7|rigid:ziitW9p3HGSZtH+w6rgxolnrn/A	false	-	biotin tag:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P01042	uniprotkb:P00748	intact:EBI-6378713|ensembl:ENSP00000493985|uniprotkb:C9JEX1|uniprotkb:A8K474|uniprotkb:B2RCR2|uniprotkb:P01043|uniprotkb:Q53EQ0|uniprotkb:Q6PAU9|uniprotkb:Q7M4P1	intact:EBI-6378830|ensembl:ENSP00000253496|uniprotkb:P78339	psi-mi:kng1_human(display_long)|uniprotkb:KNG1(gene name)|psi-mi:KNG1(display_short)|uniprotkb:BDK(gene name synonym)|uniprotkb:KNG(gene name synonym)|uniprotkb:Alpha-2-thiol proteinase inhibitor(gene name synonym)|uniprotkb:Fitzgerald factor(gene name synonym)|uniprotkb:High molecular weight kininogen(gene name synonym)|uniprotkb:Williams-Fitzgerald-Flaujeac factor(gene name synonym)	psi-mi:fa12_human(display_long)|uniprotkb:F12(gene name)|psi-mi:F12(display_short)|uniprotkb:Hageman factor(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Joseph et al. (1996)	pubmed:8710908|imex:IM-20572	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6378786|imex:IM-20572-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113889(gene)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENST00000644859(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042311"(vasodilation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR002395(HMW kininogen)|interpro:IPR018073|interpro:IPR027358|mint:P01042|rcsb pdb:1NY2|rcsb pdb:2WOK|rcsb pdb:4ASQ|rcsb pdb:4ASR|rcsb pdb:4ECB|rcsb pdb:4ECC|rcsb pdb:5I25|rcsb pdb:6F27|rcsb pdb:6F3V|rcsb pdb:6F3W|rcsb pdb:6F3X|rcsb pdb:6F3Y|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-375276|reactome:R-HSA-381426|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-8957275|go:"GO:0005615"(extracellular space)|refseq:NP_000884.1|refseq:NP_001095886.1|refseq:NP_001159923.1	ensembl:ENSG00000131187(gene)|ensembl:ENST00000253496(transcript)|go:"GO:0002353"(plasma kallikrein-kinin cascade)|go:"GO:0002542"(Factor XII activation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045087"(innate immune response)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:4BDW|rcsb pdb:4BDX|rcsb pdb:4XDE|rcsb pdb:4XE4|rcsb pdb:6B74|rcsb pdb:6B77|rcsb pdb:6GT6|rcsb pdb:6L63|rcsb pdb:6QF7|rcsb pdb:6SZW|rcsb pdb:6X0S|rcsb pdb:6X0T|reactome:R-HSA-140837|reactome:R-HSA-9657688|reactome:R-HSA-9657689|refseq:NP_000496.2	-	-	-	figure legend:"4A (1) and 5A"|agonist:zinc|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/10/31	2014/10/16	rogid:Z/DOKINto4Ygn9lYUu6nuHA3soM9606	rogid:zthfDMI8e+gVU6iCWUMwKKEGbqA9606	intact-crc:31981DC1A5809D8C|rigid:xta9gcKa5EP5q+L6QB2uzsNm7uQ	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P01042	uniprotkb:Q07021	intact:EBI-6378713|ensembl:ENSP00000493985|uniprotkb:C9JEX1|uniprotkb:A8K474|uniprotkb:B2RCR2|uniprotkb:P01043|uniprotkb:Q53EQ0|uniprotkb:Q6PAU9|uniprotkb:Q7M4P1	intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698	psi-mi:kng1_human(display_long)|uniprotkb:KNG1(gene name)|psi-mi:KNG1(display_short)|uniprotkb:BDK(gene name synonym)|uniprotkb:KNG(gene name synonym)|uniprotkb:Alpha-2-thiol proteinase inhibitor(gene name synonym)|uniprotkb:Fitzgerald factor(gene name synonym)|uniprotkb:High molecular weight kininogen(gene name synonym)|uniprotkb:Williams-Fitzgerald-Flaujeac factor(gene name synonym)	psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Joseph et al. (1996)	pubmed:8710908|imex:IM-20572	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6378786|imex:IM-20572-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113889(gene)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENST00000644859(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042311"(vasodilation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR002395(HMW kininogen)|interpro:IPR018073|interpro:IPR027358|mint:P01042|rcsb pdb:1NY2|rcsb pdb:2WOK|rcsb pdb:4ASQ|rcsb pdb:4ASR|rcsb pdb:4ECB|rcsb pdb:4ECC|rcsb pdb:5I25|rcsb pdb:6F27|rcsb pdb:6F3V|rcsb pdb:6F3W|rcsb pdb:6F3X|rcsb pdb:6F3Y|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-375276|reactome:R-HSA-381426|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-8957275|go:"GO:0005615"(extracellular space)|refseq:NP_000884.1|refseq:NP_001095886.1|refseq:NP_001159923.1	refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837	-	-	-	figure legend:"4A (1) and 5A"|agonist:zinc|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/10/31	2014/10/16	rogid:Z/DOKINto4Ygn9lYUu6nuHA3soM9606	rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606	intact-crc:31981DC1A5809D8C|rigid:xta9gcKa5EP5q+L6QB2uzsNm7uQ	false	biotin tag:?-?	sufficient binding region:74-282	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P00748	uniprotkb:P01042	intact:EBI-6378830|ensembl:ENSP00000253496|uniprotkb:P78339	intact:EBI-6378713|ensembl:ENSP00000493985|uniprotkb:C9JEX1|uniprotkb:A8K474|uniprotkb:B2RCR2|uniprotkb:P01043|uniprotkb:Q53EQ0|uniprotkb:Q6PAU9|uniprotkb:Q7M4P1	psi-mi:fa12_human(display_long)|uniprotkb:F12(gene name)|psi-mi:F12(display_short)|uniprotkb:Hageman factor(gene name synonym)	psi-mi:kng1_human(display_long)|uniprotkb:KNG1(gene name)|psi-mi:KNG1(display_short)|uniprotkb:BDK(gene name synonym)|uniprotkb:KNG(gene name synonym)|uniprotkb:Alpha-2-thiol proteinase inhibitor(gene name synonym)|uniprotkb:Fitzgerald factor(gene name synonym)|uniprotkb:High molecular weight kininogen(gene name synonym)|uniprotkb:Williams-Fitzgerald-Flaujeac factor(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Joseph et al. (1996)	pubmed:8710908|imex:IM-20572	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6378828|imex:IM-20572-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131187(gene)|ensembl:ENST00000253496(transcript)|go:"GO:0002353"(plasma kallikrein-kinin cascade)|go:"GO:0002542"(Factor XII activation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045087"(innate immune response)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:4BDW|rcsb pdb:4BDX|rcsb pdb:4XDE|rcsb pdb:4XE4|rcsb pdb:6B74|rcsb pdb:6B77|rcsb pdb:6GT6|rcsb pdb:6L63|rcsb pdb:6QF7|rcsb pdb:6SZW|rcsb pdb:6X0S|rcsb pdb:6X0T|reactome:R-HSA-140837|reactome:R-HSA-9657688|reactome:R-HSA-9657689|refseq:NP_000496.2	ensembl:ENSG00000113889(gene)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENST00000644859(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042311"(vasodilation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR002395(HMW kininogen)|interpro:IPR018073|interpro:IPR027358|mint:P01042|rcsb pdb:1NY2|rcsb pdb:2WOK|rcsb pdb:4ASQ|rcsb pdb:4ASR|rcsb pdb:4ECB|rcsb pdb:4ECC|rcsb pdb:5I25|rcsb pdb:6F27|rcsb pdb:6F3V|rcsb pdb:6F3W|rcsb pdb:6F3X|rcsb pdb:6F3Y|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-375276|reactome:R-HSA-381426|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-8957275|go:"GO:0005615"(extracellular space)|refseq:NP_000884.1|refseq:NP_001095886.1|refseq:NP_001159923.1	-	-	-	figure legend:"4B (5) and 5B"|agonist:zinc|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/10/31	2014/10/16	rogid:zthfDMI8e+gVU6iCWUMwKKEGbqA9606	rogid:Z/DOKINto4Ygn9lYUu6nuHA3soM9606	intact-crc:B576FC38AF7736F9|rigid:xta9gcKa5EP5q+L6QB2uzsNm7uQ	false	biotin tag:?-?	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P00748	uniprotkb:Q07021	intact:EBI-6378830|ensembl:ENSP00000253496|uniprotkb:P78339	intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698	psi-mi:fa12_human(display_long)|uniprotkb:F12(gene name)|psi-mi:F12(display_short)|uniprotkb:Hageman factor(gene name synonym)	psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Joseph et al. (1996)	pubmed:8710908|imex:IM-20572	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6378828|imex:IM-20572-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000131187(gene)|ensembl:ENST00000253496(transcript)|go:"GO:0002353"(plasma kallikrein-kinin cascade)|go:"GO:0002542"(Factor XII activation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0007597"(blood coagulation, intrinsic pathway)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045087"(innate immune response)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:4BDW|rcsb pdb:4BDX|rcsb pdb:4XDE|rcsb pdb:4XE4|rcsb pdb:6B74|rcsb pdb:6B77|rcsb pdb:6GT6|rcsb pdb:6L63|rcsb pdb:6QF7|rcsb pdb:6SZW|rcsb pdb:6X0S|rcsb pdb:6X0T|reactome:R-HSA-140837|reactome:R-HSA-9657688|reactome:R-HSA-9657689|refseq:NP_000496.2	refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837	-	-	-	figure legend:"4B (5) and 5B"|agonist:zinc|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/10/31	2014/10/16	rogid:zthfDMI8e+gVU6iCWUMwKKEGbqA9606	rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606	intact-crc:B576FC38AF7736F9|rigid:xta9gcKa5EP5q+L6QB2uzsNm7uQ	false	biotin tag:?-?	sufficient binding region:74-282	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)