#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06710	uniprotkb:P10443	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Gao et al. (1996)	imex:IM-18570|pubmed:8702819	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6464030|imex:IM-18570-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	-	-	-	figure legend:Fig.s 3, 6, Tables III, IV|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/14	2014/10/16	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	intact-crc:C030B1972B8DC222|rigid:/tH69MwvjJvREZ9erbuNH3NMDb0	false	-	his tag:n-n|biotin tag:n-n|sufficient binding region:543-1160	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P06710	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Gao et al. (1996)	imex:IM-18570|pubmed:8702819	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6468532|imex:IM-18570-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	-	-	-	figure legend:Fig. 3, Table IV|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:3.7x10^-10(molar)	2012/12/14	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	intact-crc:A9C384D02ED594C0|rigid:/tH69MwvjJvREZ9erbuNH3NMDb0	false	biotin tag:c-c|his tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10443	uniprotkb:P06710	intact:EBI-549111|ensemblbacteria:AAC73295|ensemblbacteria:BAA77859	intact:EBI-549140|uniprotkb:Q2MBV7|uniprotkb:Q47721|uniprotkb:A0A385XJC4|ensemblbacteria:AAC73572|ensemblbacteria:AYC08179|ensemblbacteria:BAE76249	psi-mi:dpo3a_ecoli(display_long)|uniprotkb:dnaE(gene name)|psi-mi:dnaE(display_short)|uniprotkb:polC(gene name synonym)|uniprotkb:b0184(locus name)|uniprotkb:JW0179(locus name)	psi-mi:dpo3x_ecoli(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Gao et al. (1996)	imex:IM-18570|pubmed:8702819	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6464041|imex:IM-18570-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414726.1|refseq:WP_001294757.1|dip:DIP-9458N|rcsb pdb:4JOM|rcsb pdb:5FKU|rcsb pdb:5FKV|rcsb pdb:5FKW|rcsb pdb:5M1S|rcsb pdb:4GX9|ensemblbacteria:AAC73295(transcript)|ensemblbacteria:b0184(gene)|ensemblbacteria:BAA77859(gene)|ensemblbacteria:BAA77859(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0044776"(DNA polymerase III, core complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR003141(Polymerase and histidinol phosphatase, N-terminal)|interpro:IPR004013(PHP, C-terminal)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004805(DNA polymerase III, alpha subunit)|interpro:IPR011708(Bacterial DNA polymerase III, alpha subunit)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|interpro:IPR029460|interpro:IPR040982|interpro:IPR041931|rcsb pdb:2HNH|rcsb pdb:2HQA|rcsb pdb:4GX8	refseq:NP_415003.1|refseq:WP_000122013.1|dip:DIP-9464N|ensemblbacteria:AAC73572(transcript)|ensemblbacteria:AYC08179(transcript)|ensemblbacteria:b0470(gene)|ensemblbacteria:BAE76249(gene)|ensemblbacteria:BAE76249(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043846"(DNA polymerase III, clamp loader complex)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012763(DNA polymerase III, subunits gamma and tau)|interpro:IPR021029|interpro:IPR022001|interpro:IPR022754|interpro:IPR027417|interpro:IPR038249|rcsb pdb:1JR3|rcsb pdb:1NJF|rcsb pdb:1NJG|rcsb pdb:1XXH|rcsb pdb:1XXI|rcsb pdb:2AYA|rcsb pdb:3GLF|rcsb pdb:3GLG|rcsb pdb:3GLH|rcsb pdb:3GLI|rcsb pdb:5FKU|rcsb pdb:5FKV	-	-	-	figure legend:Fig.s 3, 6, Tables IV|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/14	2014/10/16	rogid:g+4YFbE2iHTaCk4cKSf3zLmO43I83333	rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333	intact-crc:96285EB20B6D0385|rigid:/tH69MwvjJvREZ9erbuNH3NMDb0	false	necessary binding region:1112-1160|biotin tag:c-c|his tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)