#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P28632 uniprotkb:P06710-2 intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360 intact:EBI-2604194 psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name) psi-mi:p06710-2(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Xiao et al. (1993) pubmed:8505305|imex:IM-18576 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6464771|imex:IM-18576-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU intact:EBI-549140(isoform-parent) - - isoform-comment:"Formed by programmed ribosomal frameshifting to a premature stop codon in the -1 frame at codon 430, the last residue is thus Glu and not Ser. Mutants which remove the frameshift are viable, suggesting strongly that gamma is not essential for viability (Ref.14)." figure legend:Fig. 2b|complex-properties:partial gamma complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/17 2015/06/09 rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333 rogid:JMH64mXrcW06P+gZXBrJZS0hu9w83333 intact-crc:016115B8C75E1F00|rigid:46lBFmj4I5odEV3sUStntoJUtn4 false - - 1 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28905 uniprotkb:P28632 intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256 intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360 psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name) psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name) psi-mi:"MI:0071"(molecular sieving) Xiao et al. (1993) pubmed:8505305|imex:IM-18576 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6464766|imex:IM-18576-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU - crc64:7FEFFC359B28AA88 - figure legend:Fig. 3c|complex-properties:partial tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/17 2014/10/16 rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333 rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333 intact-crc:CEE86EB2862A6B7E|rigid:6eygg40CctdSrJFPP1XvK5dPiGg false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28905 uniprotkb:P06710-1 intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256 intact:EBI-6464728 psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name) psi-mi:p06710-1(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name) psi-mi:"MI:0071"(molecular sieving) Xiao et al. (1993) pubmed:8505305|imex:IM-18576 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6464766|imex:IM-18576-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU intact:EBI-549140(isoform-parent) - crc64:7FEFFC359B28AA88 isoform-comment:"Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable (Ref.14)." figure legend:Fig. 3c|complex-properties:partial tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/17 2014/10/16 rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333 rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333 intact-crc:CEE86EB2862A6B7E|rigid:6eygg40CctdSrJFPP1XvK5dPiGg false - - 1 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28905 uniprotkb:P28632 intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256 intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360 psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name) psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name) psi-mi:"MI:0071"(molecular sieving) Xiao et al. (1993) pubmed:8505305|imex:IM-18576 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6464780|imex:IM-18576-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU - crc64:7FEFFC359B28AA88 - figure legend:Fig. 2c|complex-properties:partial gamma complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/17 2015/06/09 rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333 rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333 intact-crc:BEE93093828E54A4|rigid:OpROIQkxuKisps6wqxAqWHxHWRw false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28905 uniprotkb:P06710-2 intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256 intact:EBI-2604194 psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name) psi-mi:p06710-2(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Xiao et al. (1993) pubmed:8505305|imex:IM-18576 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6464780|imex:IM-18576-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU intact:EBI-549140(isoform-parent) - crc64:7FEFFC359B28AA88 isoform-comment:"Formed by programmed ribosomal frameshifting to a premature stop codon in the -1 frame at codon 430, the last residue is thus Glu and not Ser. Mutants which remove the frameshift are viable, suggesting strongly that gamma is not essential for viability (Ref.14)." figure legend:Fig. 2c|complex-properties:partial gamma complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/17 2015/06/09 rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333 rogid:JMH64mXrcW06P+gZXBrJZS0hu9w83333 intact-crc:BEE93093828E54A4|rigid:OpROIQkxuKisps6wqxAqWHxHWRw false - - 1 3 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06710-1 uniprotkb:P28632 intact:EBI-6464728 intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360 psi-mi:p06710-1(display_long)|uniprotkb:dnaX(gene name)|psi-mi:dnaX(display_short)|uniprotkb:dnaZ(gene name synonym)|uniprotkb:dnaZX(gene name synonym)|uniprotkb:DNA polymerase III subunit gamma(gene name synonym)|uniprotkb:b0470(locus name)|uniprotkb:JW0459(locus name) psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name) psi-mi:"MI:0071"(molecular sieving) Xiao et al. (1993) pubmed:8505305|imex:IM-18576 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6464776|imex:IM-18576-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-549140(isoform-parent) refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU - isoform-comment:"Produced by full-length translation of the dnaX gene. This isoform is essential, constructs that express only the gamma isoform are not viable (Ref.14)." - figure legend:Fig. 3b|complex-properties:partial tau complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/17 2014/10/16 rogid:I70gmzAJoBvK53kEZUaKOv/zshg83333 rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333 intact-crc:51424A2D6733E3C0|rigid:ad30y0Qf4DZZz+w/YTyBEeN/yh4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28632 uniprotkb:P28905 intact:EBI-549176|uniprotkb:Q2M5U6|ensemblbacteria:AAC77325|ensemblbacteria:BAE78360 intact:EBI-549169|uniprotkb:P11649|uniprotkb:Q2M650|ensemblbacteria:AAC77216|ensemblbacteria:BAE78256 psi-mi:hold_ecoli(display_long)|uniprotkb:holD(gene name)|psi-mi:holD(display_short)|uniprotkb:b4372(locus name)|uniprotkb:JW4334(locus name) psi-mi:holc_ecoli(display_long)|uniprotkb:holC(gene name)|psi-mi:holC(display_short)|uniprotkb:b4259(locus name)|uniprotkb:JW4216(locus name) psi-mi:"MI:0071"(molecular sieving) Xiao et al. (1993) pubmed:8505305|imex:IM-18576 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6464762|imex:IM-18576-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418789.1|refseq:WP_000204012.1|dip:DIP-9934N|ensemblbacteria:AAC77325(transcript)|ensemblbacteria:b4372(gene)|ensemblbacteria:BAE78360(gene)|ensemblbacteria:BAE78360(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0009314"(response to radiation)|interpro:IPR004615(DNA polymerase III, psi subunit)|interpro:IPR018382|interpro:IPR036654|rcsb pdb:1EM8|rcsb pdb:3GLI|rcsb pdb:3SXU refseq:NP_418680.1|refseq:WP_000786400.1|dip:DIP-9933N|ensemblbacteria:AAC77216(transcript)|ensemblbacteria:b4259(gene)|ensemblbacteria:BAE78256(gene)|ensemblbacteria:BAE78256(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0009314"(response to radiation)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|go:"GO:0043847"(DNA polymerase III, clamp loader chi/psi subcomplex)|interpro:IPR007459(DNA polymerase III chi subunit, HolC)|interpro:IPR036768|rcsb pdb:1EM8|rcsb pdb:3SXU - - crc64:7FEFFC359B28AA88 figure legend:Fig. 1c|complex-properties:ch-psi complex, part of DNA Polymerase III complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/17 2014/10/16 rogid:w1FQAOKGyqkQNCRGnGeAoy5Odbk83333 rogid:tHXN16a+ZMkxJMQYo0Gd6NTQSqQ83333 intact-crc:BF7B5F5641DB72B2|rigid:Mq1IZXIavCXTUGkZ6MWMwGW8Qx8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)