#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0ACB0 uniprotkb:P0ACB0 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:"MI:0028"(cosedimentation in solution) Bujalowski et al. (1994) imex:IM-18529|pubmed:7989299 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6422277|imex:IM-18529-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM go:"GO:0030894"(replisome)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033202"(DNA helicase complex)|go:"GO:0004003" - - figure legend:Fig. 3|comment:DnaB forms trimers in the absence of MgCl2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/12/03 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 intact-crc:0BCB39F1990D0694|rigid:Hvo6SEwmmzYhi6lJOsShdd+PveA false - - 3 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0ACB0 uniprotkb:P0ACB0 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:"MI:0028"(cosedimentation in solution) Bujalowski et al. (1994) imex:IM-18529|pubmed:7989299 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6420854|imex:IM-18529-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033202"(DNA helicase complex)|go:"GO:0004003"|go:"GO:0030894"(replisome) - - figure legend:Fig.s 1, 3|complex-properties:homohexamer, unwinds double-stranded DNA at replication fork|comment:DnaB forms hexamers in the presence of MgCl2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/12/03 2014/10/16 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 intact-crc:A44C7B4FDA5F7857|rigid:Hvo6SEwmmzYhi6lJOsShdd+PveA false - - 6 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:71336" uniprotkb:P0ACB0 intact:EBI-6422249 intact:EBI-548978|uniprotkb:P03005|uniprotkb:Q2M6Q2|ensemblbacteria:AAC77022|ensemblbacteria:BAE78054 psi-mi:mant-adp(display_short)|psi-mi:"CHEBI:71336"(display_long) psi-mi:dnab_ecoli(display_long)|uniprotkb:dnaB(gene name)|psi-mi:dnaB(display_short)|uniprotkb:groP(gene name synonym)|uniprotkb:grpA(gene name synonym)|uniprotkb:b4052(locus name)|uniprotkb:JW4012(locus name) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Bujalowski et al. (1994) imex:IM-18529|pubmed:7989299 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6422240|imex:IM-18529-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_418476.1|refseq:WP_000918363.1|dip:DIP-9456N|ensemblbacteria:AAC77022(transcript)|ensemblbacteria:b4052(gene)|ensemblbacteria:BAE78054(gene)|ensemblbacteria:BAE78054(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990077"(primosome complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007692(DNA helicase, DnaB type)|interpro:IPR007693(DNA helicase, DnaB-like, N-terminal)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR016136(DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal)|interpro:IPR027417|interpro:IPR036185|rcsb pdb:1B79|rcsb pdb:1JWE|rcsb pdb:6BBM|rcsb pdb:6KZA|rcsb pdb:6QEL|rcsb pdb:6QEM go:"GO:0030894"(replisome)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033202"(DNA helicase complex)|go:"GO:0004003" - - figure legend:Fig. 2|complex-properties:homohexamer, unwinds double-stranded DNA at replication fork|complex-synonym:primary replicative helicase; DnaB protein|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/12/03 2014/10/16 - rogid:czmOnQQpFov7eFmCjLGjNhkbJ7M83333 intact-crc:8AA850E7669C5BBC false - - - 6 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)