#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06400	uniprotkb:Q9R002	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274194|imex:IM-17718-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:2b, 5E.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:xidCNX96KlQzu160polvT61k4Zw9606	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:95CEBCD9ADB01B87|rigid:XoVpfqhezDTYqAShMQgadeUj8X0	false	-	glutathione s tranferase tag:?-?|sufficient binding region:19-445	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9R002	uniprotkb:P13405	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	intact:EBI-971782|uniprotkb:Q4VA62|ensembl:ENSMUSP00000022701	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:rb_mouse(display_long)|uniprotkb:Rb1(gene name)|psi-mi:Rb1(display_short)|uniprotkb:Rb-1(gene name synonym)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp105(gene name synonym)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274176|imex:IM-17718-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|ensembl:ENSMUSG00000022105(gene)|ensembl:ENSMUST00000022701(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-MMU-113501|reactome:R-MMU-174178|reactome:R-MMU-2299718|reactome:R-MMU-2559584|reactome:R-MMU-69200|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69656|refseq:NP_033055.2|dip:DIP-37637N	-	-	-	figure legend:2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	rogid:CwWzb8jSxt1yyOBtsE5xHXHyVgc10090	intact-crc:1270E7AAA8532F11|rigid:UvSxUD/e6gMAYXvsuOsPtd+wyO8	false	sufficient binding region:19-445|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06400	uniprotkb:Q9R002	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274202|imex:IM-17718-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:xidCNX96KlQzu160polvT61k4Zw9606	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:42408C34D961F1A4|rigid:XoVpfqhezDTYqAShMQgadeUj8X0	false	-	glutathione s tranferase tag:?-?|sufficient binding region:19-445	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P13405	uniprotkb:Q9R002	intact:EBI-971782|uniprotkb:Q4VA62|ensembl:ENSMUSP00000022701	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_mouse(display_long)|uniprotkb:Rb1(gene name)|psi-mi:Rb1(display_short)|uniprotkb:Rb-1(gene name synonym)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp105(gene name synonym)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274210|imex:IM-17718-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|ensembl:ENSMUSG00000022105(gene)|ensembl:ENSMUST00000022701(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-MMU-113501|reactome:R-MMU-174178|reactome:R-MMU-2299718|reactome:R-MMU-2559584|reactome:R-MMU-69200|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69656|refseq:NP_033055.2|dip:DIP-37637N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:2b, 3.|agonist:IFN treatment|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:CwWzb8jSxt1yyOBtsE5xHXHyVgc10090	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:95EAEB66799C2BC4|rigid:UvSxUD/e6gMAYXvsuOsPtd+wyO8	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P13405	uniprotkb:Q9R002	intact:EBI-971782|uniprotkb:Q4VA62|ensembl:ENSMUSP00000022701	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_mouse(display_long)|uniprotkb:Rb1(gene name)|psi-mi:Rb1(display_short)|uniprotkb:Rb-1(gene name synonym)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp105(gene name synonym)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274186|imex:IM-17718-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|ensembl:ENSMUSG00000022105(gene)|ensembl:ENSMUST00000022701(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-MMU-113501|reactome:R-MMU-174178|reactome:R-MMU-2299718|reactome:R-MMU-2559584|reactome:R-MMU-69200|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69656|refseq:NP_033055.2|dip:DIP-37637N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:CwWzb8jSxt1yyOBtsE5xHXHyVgc10090	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:1270E7C1D8532FE4|rigid:UvSxUD/e6gMAYXvsuOsPtd+wyO8	false	-	glutathione s tranferase tag:?-?|sufficient binding region:19-445	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06400	uniprotkb:Q9R002	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274235|imex:IM-17718-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:xidCNX96KlQzu160polvT61k4Zw9606	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:F541D17C69D8DE6D|rigid:XoVpfqhezDTYqAShMQgadeUj8X0	false	-	sufficient binding region:19-445|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06400	uniprotkb:Q9R002	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6287470|imex:IM-17718-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:5E.|comment:"A natural human pRb mutant in J82 bladder carcinoma cells  ( deletion  amino acids   697- 731) was retained by GST-202 to a much lesser extent than was wild-type pRb from HeLa cells."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:xidCNX96KlQzu160polvT61k4Zw9606	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:2D2350E2777FC6AC|rigid:XoVpfqhezDTYqAShMQgadeUj8X0	false	sufficient binding region:1-696,732-928	glutathione s tranferase tag:?-?|sufficient binding region:19-445	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9R002	uniprotkb:P13405	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	intact:EBI-971782|uniprotkb:Q4VA62|ensembl:ENSMUSP00000022701	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:rb_mouse(display_long)|uniprotkb:Rb1(gene name)|psi-mi:Rb1(display_short)|uniprotkb:Rb-1(gene name synonym)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp105(gene name synonym)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274133|imex:IM-17718-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|ensembl:ENSMUSG00000022105(gene)|ensembl:ENSMUST00000022701(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-MMU-113501|reactome:R-MMU-174178|reactome:R-MMU-2299718|reactome:R-MMU-2559584|reactome:R-MMU-69200|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69656|refseq:NP_033055.2|dip:DIP-37637N	-	-	-	figure legend:2A and 5C, 6B|comment:"The binding  of  p202-(58-291) was much weaker than to  (the COOH-terminal)  p202-(295-445)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	rogid:CwWzb8jSxt1yyOBtsE5xHXHyVgc10090	intact-crc:9DE7A7C9BF8D1755|rigid:UvSxUD/e6gMAYXvsuOsPtd+wyO8	false	sufficient binding region:58-291|sufficient binding region:295-445|glutathione s tranferase tag:?-?	sufficient binding region:1-254|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P13405	uniprotkb:Q9R002	intact:EBI-971782|uniprotkb:Q4VA62|ensembl:ENSMUSP00000022701	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_mouse(display_long)|uniprotkb:Rb1(gene name)|psi-mi:Rb1(display_short)|uniprotkb:Rb-1(gene name synonym)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp105(gene name synonym)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274156|imex:IM-17718-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|ensembl:ENSMUSG00000022105(gene)|ensembl:ENSMUST00000022701(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-MMU-113501|reactome:R-MMU-174178|reactome:R-MMU-2299718|reactome:R-MMU-2559584|reactome:R-MMU-69200|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69656|refseq:NP_033055.2|dip:DIP-37637N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:2A, 5B and D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:CwWzb8jSxt1yyOBtsE5xHXHyVgc10090	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:7E3F64F0FA0B3D12|rigid:UvSxUD/e6gMAYXvsuOsPtd+wyO8	false	sufficient binding region:1-254|sufficient binding region:255-921|glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P06400	uniprotkb:Q9R002	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0096"(pull down)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274344|imex:IM-17718-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:xidCNX96KlQzu160polvT61k4Zw9606	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:78AA45AA8ABFF714|rigid:XoVpfqhezDTYqAShMQgadeUj8X0	false	sufficient binding region:379-928|glutathione s tranferase tag:?-?|mutation decreasing interaction:706-706	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P13405	uniprotkb:Q9R002	intact:EBI-971782|uniprotkb:Q4VA62|ensembl:ENSMUSP00000022701	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	psi-mi:rb_mouse(display_long)|uniprotkb:Rb1(gene name)|psi-mi:Rb1(display_short)|uniprotkb:Rb-1(gene name synonym)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp105(gene name synonym)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274227|imex:IM-17718-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|ensembl:ENSMUSG00000022105(gene)|ensembl:ENSMUST00000022701(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-MMU-113501|reactome:R-MMU-174178|reactome:R-MMU-2299718|reactome:R-MMU-2559584|reactome:R-MMU-69200|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69656|refseq:NP_033055.2|dip:DIP-37637N	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	-	-	-	figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/23	2014/10/16	rogid:CwWzb8jSxt1yyOBtsE5xHXHyVgc10090	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	intact-crc:549FBD85A0F1DD97|rigid:UvSxUD/e6gMAYXvsuOsPtd+wyO8	false	-	sufficient binding region:19-445|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9R002	uniprotkb:P13405	intact:EBI-3043899|uniprotkb:E9QLD9|ensembl:ENSMUSP00000000266|uniprotkb:P15091|uniprotkb:Q38JF1|uniprotkb:Q7TMN6|uniprotkb:Q8VEL7	intact:EBI-971782|uniprotkb:Q4VA62|ensembl:ENSMUSP00000022701	psi-mi:ifi2_mouse(display_long)|uniprotkb:Ifi202(gene name)|psi-mi:Ifi202(display_short)|uniprotkb:Ifi202a(gene name synonym)|uniprotkb:Ifi202b(gene name synonym)|uniprotkb:Interferon-inducible protein p202(gene name synonym)|uniprotkb:Lupus susceptibility protein p202(gene name synonym)	psi-mi:rb_mouse(display_long)|uniprotkb:Rb1(gene name)|psi-mi:Rb1(display_short)|uniprotkb:Rb-1(gene name synonym)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp105(gene name synonym)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Choubey et al. (1995)	imex:IM-17718|pubmed:7890747	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6274249|imex:IM-17718-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000026535(gene)|ensembl:ENSMUST00000000266(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0009617"(response to bacterium)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR004021(HIN-200/IF120x)|interpro:IPR040205|mint:Q9R002|rcsb pdb:4JBJ|rcsb pdb:4JBK|rcsb pdb:4L5Q|rcsb pdb:4L5R|rcsb pdb:4L5S|rcsb pdb:4L5T|rcsb pdb:4LNQ|refseq:NP_032353.2|refseq:NP_036070.2|refseq:XP_006536966.1	go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|ensembl:ENSMUSG00000022105(gene)|ensembl:ENSMUST00000022701(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0006325"(chromatin organization)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903944"(negative regulation of hepatocyte apoptotic process)|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|reactome:R-MMU-113501|reactome:R-MMU-174178|reactome:R-MMU-2299718|reactome:R-MMU-2559584|reactome:R-MMU-69200|reactome:R-MMU-69202|reactome:R-MMU-69231|reactome:R-MMU-69656|refseq:NP_033055.2|dip:DIP-37637N	-	-	-	figure legend:4|agonist:IFN treatment|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-akr-2b)|taxid:10090(Mus musculus AKR-2B embryo cells)	-	2012/08/23	2014/10/16	rogid:JX81lRU0ptffzmipSjfaFTlNHQE10090	rogid:CwWzb8jSxt1yyOBtsE5xHXHyVgc10090	intact-crc:A8C0BD17DDA4ADF7|rigid:UvSxUD/e6gMAYXvsuOsPtd+wyO8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)