#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q21481	uniprotkb:Q21481	intact:EBI-8299614|intact:UNK-5896167|ensemblmetazoa:M03A8.1.1	intact:EBI-8299614|intact:UNK-5896167|ensemblmetazoa:M03A8.1.1	psi-mi:q21481_caeel(display_long)|uniprotkb:CELE_M03A8.1(orf name)|uniprotkb:dhs-28(gene name)|psi-mi:dhs-28(display_short)|uniprotkb:M03A8.1(orf name)	psi-mi:q21481_caeel(display_long)|uniprotkb:CELE_M03A8.1(orf name)|uniprotkb:dhs-28(gene name)|psi-mi:dhs-28(display_short)|uniprotkb:M03A8.1(orf name)	psi-mi:"MI:0826"(x ray scattering)	Mehtälä et al. (2013)	mint:d-12-01532r1|pubmed:23313254|mint:MINT-8404622	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8299609|mint:MINT-8404646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_509146.1|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR003033(Sterol-binding)|wormbase:M03A8.1|ensemblmetazoa:M03A8.1.1(transcript)|ensemblmetazoa:WBGene00000991(gene)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0005777"(peroxisome)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019236"(response to pheromone)|go:"GO:0042811"(pheromone biosynthetic process)|go:"GO:0043053"(dauer entry)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0061063"(positive regulation of nematode larval development)|go:"GO:1904070"(ascaroside biosynthetic process)|interpro:IPR036291|interpro:IPR036527|mint:MINT-8404648(identity)	refseq:NP_509146.1|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR003033(Sterol-binding)|wormbase:M03A8.1|ensemblmetazoa:M03A8.1.1(transcript)|ensemblmetazoa:WBGene00000991(gene)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0005777"(peroxisome)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019236"(response to pheromone)|go:"GO:0042811"(pheromone biosynthetic process)|go:"GO:0043053"(dauer entry)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0061063"(positive regulation of nematode larval development)|go:"GO:1904070"(ascaroside biosynthetic process)|interpro:IPR036291|interpro:IPR036527|mint:MINT-8404648(identity)	-	comment:mint|comment:"Stoichiometry: 2.0"	comment:mint|comment:"Stoichiometry: 2.0"	figure legend:f4|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/17	2014/10/16	rogid:kadJWlrAYQOl9vDLnmNLN6UXy4E6239	rogid:kadJWlrAYQOl9vDLnmNLN6UXy4E6239	intact-crc:179CC3B9A9F1AED3|rigid:lMJhH0v48CfXrpY4ZUVUFel62XI	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9VXJ0	uniprotkb:Q9VXJ0	intact:EBI-85627|ensemblmetazoa:FBpp0073988|ensemblmetazoa:FBpp0309384	intact:EBI-85627|ensemblmetazoa:FBpp0073988|ensemblmetazoa:FBpp0309384	psi-mi:dhb4_drome(display_long)|uniprotkb:Mfe2(gene name)|psi-mi:Mfe2(display_short)|uniprotkb:CG3415(orf name)	psi-mi:dhb4_drome(display_long)|uniprotkb:Mfe2(gene name)|psi-mi:Mfe2(display_short)|uniprotkb:CG3415(orf name)	psi-mi:"MI:0826"(x ray scattering)	Mehtälä et al. (2013)	mint:d-12-01532r1|pubmed:23313254|mint:MINT-8404622	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8299561|mint:MINT-8404627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0030731|refseq:NP_573109.1|ensemblmetazoa:FBgn0030731(gene)|ensemblmetazoa:FBtr0074209(transcript)|ensemblmetazoa:FBtr0340442(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0080023"(3R-hydroxyacyl-CoA dehydratase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|rcsb pdb:3OML|reactome:R-DME-193368|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|reactome:R-DME-2046106|go:"GO:0004300"(enoyl-CoA hydratase activity)|reactome:R-DME-389887|reactome:R-DME-390247|reactome:R-DME-9033241|refseq:NP_001285318.1|mint:MINT-8404629(identity)	flybase:FBgn0030731|refseq:NP_573109.1|ensemblmetazoa:FBgn0030731(gene)|ensemblmetazoa:FBtr0074209(transcript)|ensemblmetazoa:FBtr0340442(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0080023"(3R-hydroxyacyl-CoA dehydratase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|rcsb pdb:3OML|reactome:R-DME-193368|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|reactome:R-DME-2046106|go:"GO:0004300"(enoyl-CoA hydratase activity)|reactome:R-DME-389887|reactome:R-DME-390247|reactome:R-DME-9033241|refseq:NP_001285318.1|mint:MINT-8404629(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:f2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/17	2014/10/16	rogid:GaZp2FNu8/uRe+8xPyn9m4KJl407227	rogid:GaZp2FNu8/uRe+8xPyn9m4KJl407227	intact-crc:B801BA590EB28D4B|rigid:PzAWWZgyhep9BR32EdIQuDi2CsA	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51659	uniprotkb:P51659	intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57	intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57	psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym)	psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Mehtälä et al. (2013)	mint:d-12-01532r1|pubmed:23313254|mint:MINT-8404622	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8299600|mint:MINT-8404636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500|mint:MINT-8404638(identity)	refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500|mint:MINT-8404638(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:f3|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/17	2014/10/16	rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606	rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606	intact-crc:6FA1ACE97FF805EB|rigid:Mh4AzXSqzeUVXYWc8wxvVqDSen4	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)