#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BSQ5	uniprotkb:Q9BUL8	intact:EBI-1573056|uniprotkb:Q71RE5|uniprotkb:Q8TAT4|ensembl:ENSP00000258781|uniprotkb:B3KUV0|uniprotkb:E9PDJ3|uniprotkb:A4D2L4|uniprotkb:F5H0E1|uniprotkb:F5H551|uniprotkb:D3DVL4	intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229	psi-mi:ccm2_human(display_long)|uniprotkb:CCM2(gene name)|psi-mi:CCM2(display_short)|uniprotkb:C7orf22(gene name synonym)|uniprotkb:Malcavernin(gene name synonym)|uniprotkb:PP10187(orf name)	psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fisher et al. (2013)	mint:d-12-01629r1|pubmed:23266514|mint:MINT-8404406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8286485|mint:MINT-8404432	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161406.1|ensembl:ENSG00000136280(gene)|ensembl:ENST00000258781(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001885"(endothelial cell development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0048839"(inner ear development)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060039"(pericardium development)|go:"GO:0060837"(blood vessel endothelial cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0061154"(endothelial tube morphogenesis)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR026159|interpro:IPR032375|rcsb pdb:4FQN|rcsb pdb:4TVQ|rcsb pdb:4WJ7|rcsb pdb:4Y5O|rcsb pdb:4YKC|rcsb pdb:4YKD|rcsb pdb:4YL6|refseq:NP_001025006.1|refseq:NP_001161407.1|refseq:NP_113631.1|dip:DIP-40609N|mint:MINT-8404435(identity)	ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N|mint:MINT-8404434(identity)	-	-	-	figure legend:f1d|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/12	2014/10/16	rogid:b/nQw8agXD8q1yU424GrscY0UA89606	rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606	intact-crc:0C2AB5EE52FC4780|rigid:nMZbMKQ4LwY5uDFU0wuw9SgXzCI	false	binding-associated region:1-283(MINT-8404443)|his tag:?-?(MINT-8404440)	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q9BSQ5	uniprotkb:Q9BSQ5	intact:EBI-1573056|uniprotkb:Q71RE5|uniprotkb:Q8TAT4|ensembl:ENSP00000258781|uniprotkb:B3KUV0|uniprotkb:E9PDJ3|uniprotkb:A4D2L4|uniprotkb:F5H0E1|uniprotkb:F5H551|uniprotkb:D3DVL4	intact:EBI-1573056|uniprotkb:Q71RE5|uniprotkb:Q8TAT4|ensembl:ENSP00000258781|uniprotkb:B3KUV0|uniprotkb:E9PDJ3|uniprotkb:A4D2L4|uniprotkb:F5H0E1|uniprotkb:F5H551|uniprotkb:D3DVL4	psi-mi:ccm2_human(display_long)|uniprotkb:CCM2(gene name)|psi-mi:CCM2(display_short)|uniprotkb:C7orf22(gene name synonym)|uniprotkb:Malcavernin(gene name synonym)|uniprotkb:PP10187(orf name)	psi-mi:ccm2_human(display_long)|uniprotkb:CCM2(gene name)|psi-mi:CCM2(display_short)|uniprotkb:C7orf22(gene name synonym)|uniprotkb:Malcavernin(gene name synonym)|uniprotkb:PP10187(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	Fisher et al. (2013)	mint:d-12-01629r1|pubmed:23266514|mint:MINT-8404406	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8286575|mint:MINT-8404464	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161406.1|ensembl:ENSG00000136280(gene)|ensembl:ENST00000258781(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001885"(endothelial cell development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0048839"(inner ear development)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060039"(pericardium development)|go:"GO:0060837"(blood vessel endothelial cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0061154"(endothelial tube morphogenesis)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR026159|interpro:IPR032375|rcsb pdb:4FQN|rcsb pdb:4TVQ|rcsb pdb:4WJ7|rcsb pdb:4Y5O|rcsb pdb:4YKC|rcsb pdb:4YKD|rcsb pdb:4YL6|refseq:NP_001025006.1|refseq:NP_001161407.1|refseq:NP_113631.1|dip:DIP-40609N|mint:MINT-8404466(identity)	refseq:NP_001161406.1|ensembl:ENSG00000136280(gene)|ensembl:ENST00000258781(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001885"(endothelial cell development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0048839"(inner ear development)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060039"(pericardium development)|go:"GO:0060837"(blood vessel endothelial cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0061154"(endothelial tube morphogenesis)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR026159|interpro:IPR032375|rcsb pdb:4FQN|rcsb pdb:4TVQ|rcsb pdb:4WJ7|rcsb pdb:4Y5O|rcsb pdb:4YKC|rcsb pdb:4YKD|rcsb pdb:4YL6|refseq:NP_001025006.1|refseq:NP_001161407.1|refseq:NP_113631.1|dip:DIP-40609N|mint:MINT-8404466(identity)	-	comment:"Stoichiometry: 4.0"	comment:"Stoichiometry: 4.0"	comment:mint|figure legend:f2a f2b f2c f3 st1 sf1	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/12/12	2014/10/16	rogid:b/nQw8agXD8q1yU424GrscY0UA89606	rogid:b/nQw8agXD8q1yU424GrscY0UA89606	intact-crc:64160004A4928CD6|rigid:vTj5wHtG2uwVc11IOdyHNeKOiEw	false	binding-associated region:283-379(MINT-8404474)|his tag:?-?(MINT-8404471)	binding-associated region:283-379(MINT-8404474)|his tag:?-?(MINT-8404471)	4	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)