#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60934	uniprotkb:P04489	intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433	intact:EBI-6398911	psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym)	psi-mi:e411_ade05(display_long)	psi-mi:"MI:0663"(confocal microscopy)	Ou et al. (2012)	imex:IM-18128|pubmed:23063122	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6399068|imex:IM-18128-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA  repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	-	-	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-epithelium)|taxid:9606(Homo sapiens epithelium/epithelial cells)	-	2012/11/28	2014/10/16	rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	intact-crc:A0D18F0FC61D2B9E|rigid:dBL06bePfgVSCCLrIti+oip5j9c	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P04489	uniprotkb:P04489	intact:EBI-6398911	intact:EBI-6398911	psi-mi:e411_ade05(display_long)	psi-mi:e411_ade05(display_long)	psi-mi:"MI:1024"(scanning electron microscopy)	Ou et al. (2012)	imex:IM-18128|pubmed:23063122	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6399045|imex:IM-18128-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	-	-	-	figure legend:Fig. 5, Supp. Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2012/11/28	2014/10/16	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	intact-crc:6D1DF2A2DBFBEE0B|rigid:VUizaXFTEBrbRWwSb0/fXaZsR1s	false	fusion protein:46-46	fusion protein:46-46	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P04489	uniprotkb:P04489	intact:EBI-6398911	intact:EBI-6398911	psi-mi:e411_ade05(display_long)	psi-mi:e411_ade05(display_long)	psi-mi:"MI:0663"(confocal microscopy)	Ou et al. (2012)	imex:IM-18128|pubmed:23063122	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6398910|imex:IM-18128-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	-	-	-	figure legend:Fig. 1C, 1E, 3C-F, 4D, Supp Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2012/11/28	2014/10/16	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	intact-crc:3397A0512F237FCC|rigid:VUizaXFTEBrbRWwSb0/fXaZsR1s	false	flag tag:n-n	mutation decreasing interaction strength:82-82|mutation decreasing interaction strength:71-71,82-82,86-86|myc tag:n-n	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:P04489	uniprotkb:P04489	intact:EBI-6398911	intact:EBI-6398911	psi-mi:e411_ade05(display_long)	psi-mi:e411_ade05(display_long)	psi-mi:"MI:0114"(x-ray crystallography)	Ou et al. (2012)	imex:IM-18128|pubmed:23063122	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6399010|imex:IM-18128-3|wwpdb:4djb	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	-	-	-	figure legend:Fig. 2|3d-resolution:2.05A|3d-r-factors:Rworking = 0.21 Rfree = 0.26|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/28	2014/10/16	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	intact-crc:A9CBB0F26254114F|rigid:LvpP5fOv4uaM5W+G/6VqNO8V++w	false	mutation:71-71,82-82,86-86|his tag:n-n	mutation:71-71,82-82,86-86|his tag:n-n	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P04489	uniprotkb:P04489	intact:EBI-6398911	intact:EBI-6398911	psi-mi:e411_ade05(display_long)	psi-mi:e411_ade05(display_long)	psi-mi:"MI:0071"(molecular sieving)	Ou et al. (2012)	imex:IM-18128|pubmed:23063122	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6398932|imex:IM-18128-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	go:"GO:0042802"(identical protein binding)|interpro:IPR009699(Mastadenovirus E4 ORF3)|interpro:IPR038368|rcsb pdb:4DJB|mint:P04489|refseq:AP_000230.1|dip:DIP-571N	-	-	-	figure legend:Supp. Fig. 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/11/28	2014/10/16	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	rogid:QrVWoDINatBHpKYrEh2vSgBLB4c28285	intact-crc:6314D10A01D5F9EA|rigid:LvpP5fOv4uaM5W+G/6VqNO8V++w	false	mutation:71-71,82-82,86-86|his tag:n-n|mutation:82-82	mutation:71-71,82-82,86-86|his tag:n-n|mutation:82-82	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)