#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O25608 uniprotkb:O25608 intact:EBI-7694064|ensemblbacteria:AAD07997|uniprotkb:O30585|uniprotkb:Q9AHF8|intact:MINT-179377|uniprotkb:Q9AHD6|uniprotkb:Q9AHF7 intact:EBI-7694064|ensemblbacteria:AAD07997|uniprotkb:O30585|uniprotkb:Q9AHF8|intact:MINT-179377|uniprotkb:Q9AHD6|uniprotkb:Q9AHF7 psi-mi:rdxa_helpy(display_long)|uniprotkb:HP_0954(locus name)|uniprotkb:rdxA(gene name)|psi-mi:rdxA(display_short) psi-mi:rdxa_helpy(display_long)|uniprotkb:HP_0954(locus name)|uniprotkb:rdxA(gene name)|psi-mi:rdxA(display_short) psi-mi:"MI:0114"(x-ray crystallography) Martínez-Júlvez et al. (2012) pubmed:23039228|mint:MINT-8397104 taxid:85962(helpy)|taxid:85962(Helicobacter pylori) taxid:85962(helpy)|taxid:85962(Helicobacter pylori) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8075170|mint:MINT-8397109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046677"(response to antibiotic)|interpro:IPR000415(Nitroreductase)|interpro:IPR029479|interpro:IPR033878|rcsb pdb:3QDL|ensemblbacteria:AAD07997(transcript)|ensemblbacteria:HP_0954(gene)|mint:O25608|refseq:NP_207746.1|refseq:WP_000670110.1|dip:DIP-3602N|mint:MINT-8397111(identity) go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046677"(response to antibiotic)|interpro:IPR000415(Nitroreductase)|interpro:IPR029479|interpro:IPR033878|rcsb pdb:3QDL|ensemblbacteria:AAD07997(transcript)|ensemblbacteria:HP_0954(gene)|mint:O25608|refseq:NP_207746.1|refseq:WP_000670110.1|dip:DIP-3602N|mint:MINT-8397111(identity) - function:"Reduction of a variety of nitroaromatic compounds using NADPH as source of reducing equivalents; two electrons are transferred (By similarity). Capable of reducing metronidazole; inactive rdxA renders the bacterium resistant to this compound. The reduction of metronidazole generates hydroxylamine, a potent mutagen and bactericide"|comment:mint|comment:"Stoichiometry: 2.0" function:"Reduction of a variety of nitroaromatic compounds using NADPH as source of reducing equivalents; two electrons are transferred (By similarity). Capable of reducing metronidazole; inactive rdxA renders the bacterium resistant to this compound. The reduction of metronidazole generates hydroxylamine, a potent mutagen and bactericide"|comment:mint|comment:"Stoichiometry: 2.0" comment:mint|figure legend:f1 t1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/04 2014/10/16 rogid:Q7VxQtHAbwmn+UmS8RK79rfzfTM85962 rogid:Q7VxQtHAbwmn+UmS8RK79rfzfTM85962 intact-crc:71CBCFD2176F1D34|rigid:f/Gbz8nSW9lTHsnHMYsxzcIurAk false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)