#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:B1AYL1	uniprotkb:P70587	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-7798464|intact:MINT-1785354|uniprotkb:Q9JI42	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:lrrc7_rat(display_long)|uniprotkb:Lrrc7(gene name)|psi-mi:Lrrc7(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Protein LAP1(gene name synonym)|uniprotkb:Densin-180(gene name synonym)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068372|mint:MINT-8392959	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8392961(identity)	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043194"(axon initial segment)|go:"GO:0043197"(dendritic spine)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR032675|refseq:NP_476483.1|rgd:708527|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR036034|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6798695|mint:MINT-8392964(identity)	-	comment:mint	comment:mint|function:May be involved in the organization of synaptic cell-cell contacts	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:Yno7kvbKu0yTyyomBGm8+q+Siz010116	intact-crc:A9F4EE364F54B69D|rigid:POylERPFsx10ehy6CQTNHPneTtc	false	binding-associated region:1489-1681(MINT-8392975)|glutathione s tranferase tag:?-?(MINT-8392972)	tandem tag:?-?(MINT-8392965)|binding-associated region:1392-1486(MINT-8392968)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B1AYL1	uniprotkb:P39447	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-79508|uniprotkb:E9QK00|ensembl:ENSMUSP00000099652	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:zo1_mouse(display_long)|uniprotkb:Tjp1(gene name)|psi-mi:Tjp1(display_short)|uniprotkb:Zo1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068414|mint:MINT-8392980	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8392982(identity)	go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005516"(calmodulin binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0005634"(nucleus)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0005737"(cytoplasm)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0005921"(gap junction)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045471"(response to ethanol)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0071000"(response to magnetism)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0071253"(connexin binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:0014704"(intercalated disc)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:0016020"(membrane)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035597|interpro:IPR036028|interpro:IPR036034|mint:P39447|rcsb pdb:2RRM|reactome:R-MMU-191650|reactome:R-MMU-2028269|reactome:R-MMU-351906|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|ensembl:ENSMUSG00000030516(gene)|ensembl:ENSMUST00000102592(transcript)|go:"GO:0001825"(blastocyst formation)|refseq:NP_033412.2|dip:DIP-30946N|mint:MINT-8392988(identity)	-	comment:mint	-	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:wvslyL15GCrtwUReZEC9DiNvPEk10090	intact-crc:E702F8631945BB9E|rigid:Su2q+NZ4TBq6/YXrt2nYjywuYOY	false	glutathione s tranferase tag:?-?(MINT-8392985)|binding-associated region:1489-1681(MINT-8392983)	binding-associated region:417-567(MINT-8392989)|tandem tag:?-?(MINT-8392992)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B1AYL1	uniprotkb:Q96RT1	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|ensembl:ENSP00000284037|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068438|mint:MINT-8392997	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8392999(identity)	refseq:NP_001240628.1|refseq:NP_001240630.1|ensembl:ENSG00000112851(gene)|ensembl:ENST00000284037(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045175"(basal protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR032927|interpro:IPR036034|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBG|rcsb pdb:6UBH|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013408|reactome:R-HSA-9013106|reactome:R-HSA-9013423|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_061165.1|refseq:NP_001240626.1|refseq:NP_001240627.1|mint:MINT-8393005(identity)	-	comment:mint	-	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606	intact-crc:6850A89E1D9721B0|rigid:5FqLZnxlyrscy4UaUKLkdxeOl8I	false	binding-associated region:1489-1681(MINT-8393002)|glutathione s tranferase tag:?-?(MINT-8393000)	tandem tag:?-?(MINT-8393006)|binding-associated region:1274-1372(MINT-8393008)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B1AYL1	uniprotkb:P29475	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-7164065|intact:EBI-28983773|ensembl:ENSP00000320758|uniprotkb:O75713|uniprotkb:E9PH30|intact:MINT-122019	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:nos1_human(display_long)|uniprotkb:NOS1(gene name)|psi-mi:NOS1(display_short)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)|uniprotkb:bNOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068462|mint:MINT-8393014	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393016(identity)	refseq:XP_011536700.1|ensembl:ENSP00000320758|ensembl:ENST00000338101|ensembl:ENSP00000337459|ensembl:ENST00000618760|ensembl:ENSP00000477999|ensembl:ENSG00000089250(gene)|ensembl:ENST00000317775(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007520"(myoblast fusion)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0010523"(negative regulation of calcium ion transport into cytosol)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0020037"(heme binding)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042738"|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051612"(negative regulation of serotonin uptake)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098924"(retrograde trans-synaptic signaling by nitric oxide)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|rcsb pdb:5UO1|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036034|interpro:IPR036119|interpro:IPR039261|mint:P29475|rcsb pdb:4D1N|rcsb pdb:4UCH|rcsb pdb:4UH5|rcsb pdb:4UH6|rcsb pdb:4V3U|rcsb pdb:5ADF|rcsb pdb:5ADG|rcsb pdb:5ADI|rcsb pdb:5FVU|rcsb pdb:5FVV|rcsb pdb:5FVW|rcsb pdb:5FVX|rcsb pdb:5UO3|rcsb pdb:5UO4|rcsb pdb:5UO5|rcsb pdb:5UO6|rcsb pdb:5UO7|rcsb pdb:5VUV|rcsb pdb:5VUW|rcsb pdb:5VUX|rcsb pdb:5VUY|rcsb pdb:5VUZ|rcsb pdb:5VV0|rcsb pdb:5VV1|rcsb pdb:5VV2|rcsb pdb:5VV3|rcsb pdb:5VV4|rcsb pdb:5VV5|rcsb pdb:6AUY|rcsb pdb:6AUZ|rcsb pdb:6AV0|rcsb pdb:6AV1|rcsb pdb:6AV2|rcsb pdb:6AV3|rcsb pdb:6AV4|rcsb pdb:6AV5|rcsb pdb:6CIC|rcsb pdb:6CID|rcsb pdb:6NG1|rcsb pdb:6NG2|rcsb pdb:6NG4|rcsb pdb:6NG5|rcsb pdb:6NG6|rcsb pdb:6NG7|rcsb pdb:6NG8|rcsb pdb:6NGA|rcsb pdb:6NGB|rcsb pdb:6NGC|rcsb pdb:6NGD|rcsb pdb:6NGE|rcsb pdb:6NGF|rcsb pdb:5UO2|rcsb pdb:6NGH|rcsb pdb:6NGI|rcsb pdb:6NHB|rcsb pdb:6NHC|rcsb pdb:6PNA|rcsb pdb:6PNB|rcsb pdb:6PNC|rcsb pdb:6PND|rcsb pdb:6PNE|rcsb pdb:6PNF|rcsb pdb:6PNG|rcsb pdb:6PNH|rcsb pdb:6PO5|rcsb pdb:6PO7|rcsb pdb:6PO8|rcsb pdb:6PO9|rcsb pdb:6POA|rcsb pdb:6POB|rcsb pdb:6POC|rcsb pdb:6POT|reactome:R-HSA-1222556|reactome:R-HSA-392154|reactome:R-HSA-5578775|refseq:NP_001191143.1|refseq:NP_000611.1|refseq:NP_001191147.1|refseq:NP_001191142.1|refseq:XP_016874834.1|refseq:XP_016874835.1|refseq:XP_016874836.1|dip:DIP-40999N|mint:MINT-8393022(identity)	-	comment:mint	comment:mint|function:"Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter"|function:"Genetic variations in NOS1 gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1 (IHPS1) [MIM:179010]. IHPS has an incidence of 1-5 per 1'000 live births in whites and a marked preponderance of males to females (4:1). IHPS is the most frequent disorder requiring surgery in the first year of life. The disorder is characterized by hypertrophy and hyperplasia of the circular muscle layer of the pylorus, leading to persistent vomiting 2-12 weeks after birth. Defective pyloric relaxation and increased pyloric smooth muscle mass have been suggested to be responsible for gastric-outlet obstruction"	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:El1bLhrX0trPS1atMOWTFpDa3XU9606	intact-crc:F83FCA29837C3F4E|rigid:aeej2xhehQdKy/KsyoWXnx8rPWc	false	glutathione s tranferase tag:?-?(MINT-8393019)|binding-associated region:1489-1681(MINT-8393017)	binding-associated region:228-352(MINT-8393023)|tandem tag:?-?(MINT-8393026)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B1AYL1	uniprotkb:Q9Y4G8	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-307079|ensembl:ENSP00000264431|uniprotkb:D3DP27	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:rpgf2_human(display_long)|uniprotkb:RAPGEF2(gene name)|psi-mi:RAPGEF2(display_short)|uniprotkb:KIAA0313(gene name synonym)|uniprotkb:PDZGEF1(gene name synonym)|uniprotkb:NRAPGEP(gene name synonym)|uniprotkb:Neural RAP guanine nucleotide exchange protein(gene name synonym)|uniprotkb:PDZ domain-containing guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:Cyclic nucleotide ras GEF(gene name synonym)|uniprotkb:RA-GEF-1(gene name synonym)|uniprotkb:Ras/Rap1-associating GEF-1(gene name synonym)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068510|mint:MINT-8393048	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393050(identity)	ensembl:ENSG00000109756(gene)|ensembl:ENST00000264431(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001568"(blood vessel development)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0021591"(ventricular system development)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031547"(brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|go:"GO:2001214"(positive regulation of vasculogenesis)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000159(Ras-association)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR023578|interpro:IPR029071|interpro:IPR030739|interpro:IPR036034|mint:Q9Y4G8|rcsb pdb:6QDT|reactome:R-HSA-5673001|refseq:NP_055062.1|mint:MINT-8393056(identity)	-	comment:mint	-	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:48dAec6oA8l8w3E0/yh+6v7BRr49606	intact-crc:C5F77D1DDEECD848|rigid:+EwuLAjAeD7X+eSrQXHVcMHAdPM	false	binding-associated region:1489-1681(MINT-8393051)|glutathione s tranferase tag:?-?(MINT-8393053)	tandem tag:?-?(MINT-8393060)|binding-associated region:398-522(MINT-8393057)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70263	uniprotkb:B1AYL1	intact:EBI-7650391|ensembl:ENSMUSP00000084405|ensembl:ENSMUSP00000113035|intact:MINT-253029|uniprotkb:O70264|uniprotkb:Q8BRI8|uniprotkb:Q8CFR3	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	psi-mi:lnx1_mouse(display_long)|uniprotkb:Lnx1(gene name)|psi-mi:Lnx1(display_short)|uniprotkb:Lnx(gene name synonym)|uniprotkb:Ligand of Numb-binding protein 1(gene name synonym)|uniprotkb:Numb-binding protein 1(gene name synonym)|uniprotkb:Ligand of Numb protein X 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase LNX(gene name synonym)	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068486|mint:MINT-8393031	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000029228(gene)|ensembl:ENSMUST00000087161(transcript)|ensembl:ENSMUST00000117388(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036034|mint:O70263|rcsb pdb:3VQF|rcsb pdb:3VQG|reactome:R-MMU-983168|refseq:NP_001153050.1|refseq:NP_001153051.1|refseq:NP_034857.3|refseq:NP_001153052.1|refseq:NP_001153049.1|refseq:XP_006504317.1|mint:MINT-8393039(identity)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393033(identity)	-	function:Isoform 2 provides an endocytic scaffold for IGSF5/JAM4|function:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65|comment:mint	comment:mint	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:shmkiB+D/B2GzRLu117bgR7QopI10090	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	intact-crc:1F75701289325A37|rigid:gxAYRBU2eHRTAn+LM3n8QykxzbM	false	tandem tag:?-?(MINT-8393040)|binding-associated region:402-531(MINT-8393042)	glutathione s tranferase tag:?-?(MINT-8393034)|binding-associated region:1489-1681(MINT-8393036)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:B1AYL1	uniprotkb:Q99L88	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-295943|uniprotkb:O35925|ensembl:ENSMUSP00000041294	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:sntb1_mouse(display_long)|uniprotkb:Sntb1(gene name)|psi-mi:Sntb1(display_short)|uniprotkb:Snt2b1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068608|mint:MINT-8393082	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393084(identity)	go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q99L88|ensembl:ENSMUSG00000060429(gene)|ensembl:ENSMUST00000039769(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_057876.1|refseq:XP_006520734.1|mint:MINT-8393090(identity)	-	comment:mint	-	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:s9YcOAVq5wEohYlPv5lLHlu62Sc10090	intact-crc:A9036AD647E2F545|rigid:dogdVIppMGHDe+tublV8H4xOps0	false	binding-associated region:1489-1681(MINT-8393085)|glutathione s tranferase tag:?-?(MINT-8393087)	binding-associated region:106-252(MINT-8393091)|tandem tag:?-?(MINT-8393094)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B1AYL1	uniprotkb:Q62696	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-389325	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068570|mint:MINT-8393065	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393067(identity)	rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N|mint:MINT-8393073(identity)	-	comment:mint	-	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116	intact-crc:57307BC2BF9FB31D|rigid:qvpN5DFbZUSiSrXLjWDKtC70X7Y	false	glutathione s tranferase tag:?-?(MINT-8393068)|binding-associated region:1489-1681(MINT-8393070)	binding-associated region:218-458(MINT-8393076)|tandem tag:?-?(MINT-8393074)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B1AYL1	uniprotkb:Q9Z254	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-991162|uniprotkb:Q6GR70|uniprotkb:Q9QUQ4|ensembl:ENSRNOP00000005374	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:gipc1_rat(display_long)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:GLUT1 C-terminal-binding protein(gene name synonym)|uniprotkb:Gipc1(gene name)|psi-mi:Gipc1(display_short)|uniprotkb:Gipc(gene name synonym)|uniprotkb:Rgs19ip1(gene name synonym)|uniprotkb:Synectin(gene name synonym)	psi-mi:"MI:0089"(protein array)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068632|mint:MINT-8393099	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393101(identity)	rgd:68338|refseq:NP_445793.1|ensembl:ENSRNOG00000003864(gene)|ensembl:ENSRNOT00000005374(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|go:"GO:0005903"(brush border)|refseq:XP_017456861.1|mint:MINT-8393107(identity)	-	comment:mint	-	comment:domino|comment:mint|figure legend:st1 f1c	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:uqwJJv2JErOO2NJR8CVIxCflozU10116	intact-crc:F84E51ADE4A47284|rigid:KF1z7B6ZZeNUlGwyWM1GSNmZhy0	false	glutathione s tranferase tag:?-?(MINT-8393102)|binding-associated region:1489-1681(MINT-8393104)	binding-associated region:150-290(MINT-8393110)|tandem tag:?-?(MINT-8393108)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B1AYL1	uniprotkb:Q62696	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-389325	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068664|mint:MINT-8393119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393122(identity)	rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N|mint:MINT-8393121(identity)	-	comment:mint	-	figure legend:f3a|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116	intact-crc:35EC0C805E9344DA|rigid:qvpN5DFbZUSiSrXLjWDKtC70X7Y	false	glutathione s tranferase tag:?-?(MINT-8393125)|binding-associated region:1679-1681(MINT-8393128)	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0113"(western blot)
uniprotkb:B1AYL1	uniprotkb:Q811D0	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-514290|uniprotkb:Q62402|uniprotkb:Q6PGB5|uniprotkb:Q8CGN7|ensembl:ENSMUSP00000097581|ensembl:ENSMUSP00000110859	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:dlg1_mouse(display_long)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Embryo-dlg/synapse-associated protein 97(gene name synonym)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068706|mint:MINT-8393136	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393139(identity)	refseq:NP_031888.2|refseq:NP_001239362.1|refseq:NP_001239364.1|refseq:XP_006521831.1|refseq:NP_001239363.1|dip:DIP-31591N|ensembl:ENSMUSG00000022770(gene)|ensembl:ENSMUST00000100001(transcript)|ensembl:ENSMUST00000115205(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q811D0|rcsb pdb:4OAJ|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-8849932|mint:MINT-8393138(identity)	-	comment:mint	-	figure legend:f3b|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:b8LjYbiuR2K6/jxhwU1hxBJKX6410090	intact-crc:E4F70A37B32E0AEF|rigid:pzY7uYiFlt+kjoSjEzwEwWHQyKk	false	flag tag:?-?(MINT-8393141)|mutation disrupting interaction:1679-1679(MINT-8393163)	myc tag:?-?(MINT-8393145)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:B1AYL1	uniprotkb:Q62696	intact:EBI-8068354|intact:MINT-8392826|ensembl:ENSMUSP00000042405	intact:EBI-389325	psi-mi:b1ayl1_mouse(display_long)|uniprotkb:Scn7a(gene name)|psi-mi:Scn7a(display_short)	psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Matsumoto et al. (2012)	mint:d-12-01303r1|pubmed:23022437|mint:MINT-8392790	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068770|mint:MINT-8393152	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033161.2|ensembl:ENSMUSG00000034810(gene)|ensembl:ENSMUST00000042792(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005272"(sodium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0009617"(response to bacterium)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0097386"(glial cell projection)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR027359|interpro:IPR028812|interpro:IPR043203|interpro:IPR044564|reactome:R-MMU-5576892|mint:MINT-8393154(identity)	rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N|mint:MINT-8393155(identity)	go:"GO:0005886"(plasma membrane)	comment:mint	-	figure legend:f4a|comment:mint	taxid:10116(rat-c6)|taxid:10116(Rattus norvegicus)	-	2012/09/13	2014/10/16	rogid:O4ohvJIBFsL35Hb4iTpl5sG81bQ10090	rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116	intact-crc:55B1D279B10CB715|rigid:qvpN5DFbZUSiSrXLjWDKtC70X7Y	false	mutation disrupting interaction:1679-1679(MINT-8393167)	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)