#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B ensembl:ENSMUSG00000000791 uniprotkb:B2RWS6 intact:EBI-6398451 intact:EBI-3953360|ensembl:ENSMUSP00000066789|uniprotkb:E9PYJ8 psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:ep300_mouse(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:Ep300(gene name)|psi-mi:Ep300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398796|imex:IM-18126-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003823"(antigen binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000055024(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|ensembl:ENSMUST00000068387(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0009749"(response to glucose)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031325"(positive regulation of cellular metabolic process)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036268"(swimming)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031324"(negative regulation of cellular metabolic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0140067"(peptidyl-lysine butyrylation)|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000629"(negative regulation of miRNA metabolic process)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-3899300|reactome:R-MMU-5250924|reactome:R-MMU-5621575|reactome:R-MMU-5689901|reactome:R-MMU-6781823|reactome:R-MMU-6782210|reactome:R-MMU-6804758|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-8866907|reactome:R-MMU-8936459|reactome:R-MMU-8939243|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519|reactome:R-MMU-9029569|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-6782135|refseq:NP_808489.4|dip:DIP-60610N - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:+i8zWNbBTzr6QvuKBIIPiIDIxQg10090 intact-crc:1F8ABA0E2A0429AE false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000025929 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-4566324 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398675|imex:IM-18126-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:515CCE0481A09336 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000041872 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398447 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:il17f_mouse_gene(display_short)|psi-mi:ENSMUSG00000041872(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398717|imex:IM-18126-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:45DC2731B1E002E8 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000028150 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-4422030 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398621|imex:IM-18126-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:581BDD6E70405A27 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000026072 uniprotkb:B2RWS6 intact:EBI-6398437 intact:EBI-3953360|ensembl:ENSMUSP00000066789|uniprotkb:E9PYJ8 psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:ep300_mouse(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:Ep300(gene name)|psi-mi:Ep300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398584|imex:IM-18126-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003823"(antigen binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000055024(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|ensembl:ENSMUST00000068387(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0009749"(response to glucose)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031325"(positive regulation of cellular metabolic process)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036268"(swimming)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031324"(negative regulation of cellular metabolic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0140067"(peptidyl-lysine butyrylation)|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000629"(negative regulation of miRNA metabolic process)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-3899300|reactome:R-MMU-5250924|reactome:R-MMU-5621575|reactome:R-MMU-5689901|reactome:R-MMU-6781823|reactome:R-MMU-6782210|reactome:R-MMU-6804758|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-8866907|reactome:R-MMU-8936459|reactome:R-MMU-8939243|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519|reactome:R-MMU-9029569|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-6782135|refseq:NP_808489.4|dip:DIP-60610N - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:+i8zWNbBTzr6QvuKBIIPiIDIxQg10090 intact-crc:ACFBDEEC1B68F875 false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54843 ensembl:ENSMUSG00000000791 intact:EBI-3842521|uniprotkb:Q3V1Z2|uniprotkb:Q4QY62|ensembl:ENSMUSP00000104732 intact:EBI-6398451 psi-mi:maf_mouse(display_long)|uniprotkb:Maf(gene name)|psi-mi:Maf(display_short)|uniprotkb:Maf2(gene name synonym)|uniprotkb:Proto-oncogene c-Maf(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog(gene name synonym) psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398784|imex:IM-18126-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001020748.2|ensembl:ENSMUSG00000055435(gene)|ensembl:ENSMUST00000109104(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR028573|mint:P54843|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048839"(inner ear development)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:y2pVxicE448zN3pch03yKPlK+ng10090 - intact-crc:7C2ADE6CC5FAEAB3 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000028150 uniprotkb:Q61164 intact:EBI-4422030 intact:EBI-932785|ensembl:ENSMUSP00000005841 psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398651|imex:IM-18126-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436 - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090 intact-crc:C490BF727C38DBFF false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P42227 ensembl:ENSMUSG00000025929 intact:EBI-602878|uniprotkb:A2A5D1|uniprotkb:B7ZC17|ensembl:ENSMUSP00000120152 intact:EBI-4566324 psi-mi:stat3_mouse(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:Stat3(gene name)|psi-mi:Stat3(display_short)|uniprotkb:Aprf(gene name synonym) psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398681|imex:IM-18126-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_998824.1|refseq:NP_998825.1|dip:DIP-442N|ensembl:ENSMUSG00000004040(gene)|ensembl:ENSMUST00000127638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|mint:P42227|rcsb pdb:1BG1|rcsb pdb:3CWG|rcsb pdb:4E68|rcsb pdb:4ZIA|reactome:R-MMU-1059683|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6783783|reactome:R-MMU-6785807|reactome:R-MMU-8849474|reactome:R-MMU-8854691|reactome:R-MMU-8875791|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9008059|reactome:R-MMU-9020933|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-8983432 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:jWu9RTbZkTUtGrXQlg1K79zHowM10090 - intact-crc:E97309EBE4D1B3B4 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000041872 uniprotkb:P51450 intact:EBI-6398447 intact:EBI-4422044|uniprotkb:E9Q8I1|uniprotkb:Q3U513|uniprotkb:Q61027|uniprotkb:Q91YT5|uniprotkb:Q9QXD9|uniprotkb:Q9R177 psi-mi:il17f_mouse_gene(display_short)|psi-mi:ENSMUSG00000041872(display_long) psi-mi:rorg_mouse(display_long)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398735|imex:IM-18126-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001280663.1|refseq:NP_035411.2|reactome:R-MMU-383280|dip:DIP-59439N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048535"(lymph node development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101 - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:UN/SJWwC1Jl05UgqUvGdYMPJLas10090 intact-crc:D8B5561F1FD4CF0F false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P42227 ensembl:ENSMUSG00000026072 intact:EBI-602878|uniprotkb:A2A5D1|uniprotkb:B7ZC17|ensembl:ENSMUSP00000120152 intact:EBI-6398437 psi-mi:stat3_mouse(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:Stat3(gene name)|psi-mi:Stat3(display_short)|uniprotkb:Aprf(gene name synonym) psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398566|imex:IM-18126-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_998824.1|refseq:NP_998825.1|dip:DIP-442N|ensembl:ENSMUSG00000004040(gene)|ensembl:ENSMUST00000127638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|mint:P42227|rcsb pdb:1BG1|rcsb pdb:3CWG|rcsb pdb:4E68|rcsb pdb:4ZIA|reactome:R-MMU-1059683|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6783783|reactome:R-MMU-6785807|reactome:R-MMU-8849474|reactome:R-MMU-8854691|reactome:R-MMU-8875791|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9008059|reactome:R-MMU-9020933|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-8983432 - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:jWu9RTbZkTUtGrXQlg1K79zHowM10090 - intact-crc:49E0C4CFF21E2D2D false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000028150 uniprotkb:O35284 intact:EBI-4422030 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398615|imex:IM-18126-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 intact-crc:B749AF1C87C6BBAD false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54843 ensembl:ENSMUSG00000028150 intact:EBI-3842521|uniprotkb:Q3V1Z2|uniprotkb:Q4QY62|ensembl:ENSMUSP00000104732 intact:EBI-4422030 psi-mi:maf_mouse(display_long)|uniprotkb:Maf(gene name)|psi-mi:Maf(display_short)|uniprotkb:Maf2(gene name synonym)|uniprotkb:Proto-oncogene c-Maf(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog(gene name synonym) psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398633|imex:IM-18126-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001020748.2|ensembl:ENSMUSG00000055435(gene)|ensembl:ENSMUST00000109104(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR028573|mint:P54843|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048839"(inner ear development)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874 - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:y2pVxicE448zN3pch03yKPlK+ng10090 - intact-crc:F14C4316677B2847 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000025929 uniprotkb:B2RWS6 intact:EBI-4566324 intact:EBI-3953360|ensembl:ENSMUSP00000066789|uniprotkb:E9PYJ8 psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:ep300_mouse(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:Ep300(gene name)|psi-mi:Ep300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398699|imex:IM-18126-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003823"(antigen binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000055024(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|ensembl:ENSMUST00000068387(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0009749"(response to glucose)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031325"(positive regulation of cellular metabolic process)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036268"(swimming)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031324"(negative regulation of cellular metabolic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0140067"(peptidyl-lysine butyrylation)|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000629"(negative regulation of miRNA metabolic process)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-3899300|reactome:R-MMU-5250924|reactome:R-MMU-5621575|reactome:R-MMU-5689901|reactome:R-MMU-6781823|reactome:R-MMU-6782210|reactome:R-MMU-6804758|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-8866907|reactome:R-MMU-8936459|reactome:R-MMU-8939243|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519|reactome:R-MMU-9029569|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-6782135|refseq:NP_808489.4|dip:DIP-60610N - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:+i8zWNbBTzr6QvuKBIIPiIDIxQg10090 intact-crc:73E0621DE8042B67 false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000025929 uniprotkb:P51450 intact:EBI-4566324 intact:EBI-4422044|uniprotkb:E9Q8I1|uniprotkb:Q3U513|uniprotkb:Q61027|uniprotkb:Q91YT5|uniprotkb:Q9QXD9|uniprotkb:Q9R177 psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:rorg_mouse(display_long)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398693|imex:IM-18126-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001280663.1|refseq:NP_035411.2|reactome:R-MMU-383280|dip:DIP-59439N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048535"(lymph node development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101 - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:UN/SJWwC1Jl05UgqUvGdYMPJLas10090 intact-crc:ECB683001E2A59D8 false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000041872 uniprotkb:Q64287 intact:EBI-6398447 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 psi-mi:il17f_mouse_gene(display_short)|psi-mi:ENSMUSG00000041872(display_long) psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398711|imex:IM-18126-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 intact-crc:A3BE91BA292C1AAD false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000028150 uniprotkb:B2RWS6 intact:EBI-4422030 intact:EBI-3953360|ensembl:ENSMUSP00000066789|uniprotkb:E9PYJ8 psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:ep300_mouse(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:Ep300(gene name)|psi-mi:Ep300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398645|imex:IM-18126-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003823"(antigen binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000055024(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|ensembl:ENSMUST00000068387(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0009749"(response to glucose)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031325"(positive regulation of cellular metabolic process)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036268"(swimming)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031324"(negative regulation of cellular metabolic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0140067"(peptidyl-lysine butyrylation)|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000629"(negative regulation of miRNA metabolic process)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-3899300|reactome:R-MMU-5250924|reactome:R-MMU-5621575|reactome:R-MMU-5689901|reactome:R-MMU-6781823|reactome:R-MMU-6782210|reactome:R-MMU-6804758|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-8866907|reactome:R-MMU-8936459|reactome:R-MMU-8939243|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519|reactome:R-MMU-9029569|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-6782135|refseq:NP_808489.4|dip:DIP-60610N - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:+i8zWNbBTzr6QvuKBIIPiIDIxQg10090 intact-crc:C8DBDEECED5C43D4 false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000028150 uniprotkb:P51450 intact:EBI-4422030 intact:EBI-4422044|uniprotkb:E9Q8I1|uniprotkb:Q3U513|uniprotkb:Q61027|uniprotkb:Q91YT5|uniprotkb:Q9QXD9|uniprotkb:Q9R177 psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:rorg_mouse(display_long)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398639|imex:IM-18126-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001280663.1|refseq:NP_035411.2|reactome:R-MMU-383280|dip:DIP-59439N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048535"(lymph node development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101 - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:UN/SJWwC1Jl05UgqUvGdYMPJLas10090 intact-crc:B143E946ED5B51E0 false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q61164 ensembl:ENSMUSG00000026072 intact:EBI-932785|ensembl:ENSMUSP00000005841 intact:EBI-6398437 psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym) psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398596|imex:IM-18126-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436 - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090 - intact-crc:B1F4E427D23862B8 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54843 ensembl:ENSMUSG00000026072 intact:EBI-3842521|uniprotkb:Q3V1Z2|uniprotkb:Q4QY62|ensembl:ENSMUSP00000104732 intact:EBI-6398437 psi-mi:maf_mouse(display_long)|uniprotkb:Maf(gene name)|psi-mi:Maf(display_short)|uniprotkb:Maf2(gene name synonym)|uniprotkb:Proto-oncogene c-Maf(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog(gene name synonym) psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398572|imex:IM-18126-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001020748.2|ensembl:ENSMUSG00000055435(gene)|ensembl:ENSMUST00000109104(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR028573|mint:P54843|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048839"(inner ear development)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874 - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:y2pVxicE448zN3pch03yKPlK+ng10090 - intact-crc:84281843C97B9100 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000000791 uniprotkb:P51450 intact:EBI-6398451 intact:EBI-4422044|uniprotkb:E9Q8I1|uniprotkb:Q3U513|uniprotkb:Q61027|uniprotkb:Q91YT5|uniprotkb:Q9QXD9|uniprotkb:Q9R177 psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:rorg_mouse(display_long)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398790|imex:IM-18126-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001280663.1|refseq:NP_035411.2|reactome:R-MMU-383280|dip:DIP-59439N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048535"(lymph node development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101 - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:UN/SJWwC1Jl05UgqUvGdYMPJLas10090 intact-crc:6C53791D095D9B9A false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000041872 uniprotkb:B2RWS6 intact:EBI-6398447 intact:EBI-3953360|ensembl:ENSMUSP00000066789|uniprotkb:E9PYJ8 psi-mi:il17f_mouse_gene(display_short)|psi-mi:ENSMUSG00000041872(display_long) psi-mi:ep300_mouse(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:Ep300(gene name)|psi-mi:Ep300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398741|imex:IM-18126-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003823"(antigen binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSMUSG00000055024(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|ensembl:ENSMUST00000068387(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0009749"(response to glucose)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010560"(positive regulation of glycoprotein biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031325"(positive regulation of cellular metabolic process)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036268"(swimming)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031324"(negative regulation of cellular metabolic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0065004"(protein-DNA complex assembly)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0140067"(peptidyl-lysine butyrylation)|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000629"(negative regulation of miRNA metabolic process)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-3899300|reactome:R-MMU-5250924|reactome:R-MMU-5621575|reactome:R-MMU-5689901|reactome:R-MMU-6781823|reactome:R-MMU-6782210|reactome:R-MMU-6804758|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-8866907|reactome:R-MMU-8936459|reactome:R-MMU-8939243|reactome:R-MMU-8941856|reactome:R-MMU-8941858|reactome:R-MMU-8951936|reactome:R-MMU-9018519|reactome:R-MMU-9029569|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-6782135|refseq:NP_808489.4|dip:DIP-60610N - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:+i8zWNbBTzr6QvuKBIIPiIDIxQg10090 intact-crc:FE7FEF82AE042946 false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000026072 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398437 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398539|imex:IM-18126-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:3AD9AA2B31D6E6F7 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000000791 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398451 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398765|imex:IM-18126-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:1758BEB83FA54E38 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000041872 uniprotkb:Q61164 intact:EBI-6398447 intact:EBI-932785|ensembl:ENSMUSP00000005841 psi-mi:il17f_mouse_gene(display_short)|psi-mi:ENSMUSG00000041872(display_long) psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398747|imex:IM-18126-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436 - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090 intact-crc:BB3F494C1DF4EC7F false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000000791 uniprotkb:O35284 intact:EBI-6398451 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398777|imex:IM-18126-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 intact-crc:D1B9341996D75174 false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000025929 uniprotkb:Q64287 intact:EBI-4566324 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398669|imex:IM-18126-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 intact-crc:97BD44A528D28C7A false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54843 ensembl:ENSMUSG00000041872 intact:EBI-3842521|uniprotkb:Q3V1Z2|uniprotkb:Q4QY62|ensembl:ENSMUSP00000104732 intact:EBI-6398447 psi-mi:maf_mouse(display_long)|uniprotkb:Maf(gene name)|psi-mi:Maf(display_short)|uniprotkb:Maf2(gene name synonym)|uniprotkb:Proto-oncogene c-Maf(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog(gene name synonym) psi-mi:il17f_mouse_gene(display_short)|psi-mi:ENSMUSG00000041872(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398729|imex:IM-18126-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001020748.2|ensembl:ENSMUSG00000055435(gene)|ensembl:ENSMUST00000109104(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR028573|mint:P54843|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048839"(inner ear development)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:y2pVxicE448zN3pch03yKPlK+ng10090 - intact-crc:C8CCF16ED373BE26 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000026072 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398437 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398483|imex:IM-18126-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:D58BD859C650077D false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000000791 uniprotkb:Q61164 intact:EBI-6398451 intact:EBI-932785|ensembl:ENSMUSP00000005841 psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398802|imex:IM-18126-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436 - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090 intact-crc:0FD9664E0B7DB8EA false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P54843 ensembl:ENSMUSG00000025929 intact:EBI-3842521|uniprotkb:Q3V1Z2|uniprotkb:Q4QY62|ensembl:ENSMUSP00000104732 intact:EBI-4566324 psi-mi:maf_mouse(display_long)|uniprotkb:Maf(gene name)|psi-mi:Maf(display_short)|uniprotkb:Maf2(gene name synonym)|uniprotkb:Proto-oncogene c-Maf(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog(gene name synonym) psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398687|imex:IM-18126-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_001020748.2|ensembl:ENSMUSG00000055435(gene)|ensembl:ENSMUST00000109104(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR028573|mint:P54843|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048839"(inner ear development)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:y2pVxicE448zN3pch03yKPlK+ng10090 - intact-crc:FCCF2471D28D28F1 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000028150 uniprotkb:P42227 intact:EBI-4422030 intact:EBI-602878|uniprotkb:A2A5D1|uniprotkb:B7ZC17|ensembl:ENSMUSP00000120152 psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:stat3_mouse(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:Stat3(gene name)|psi-mi:Stat3(display_short)|uniprotkb:Aprf(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398627|imex:IM-18126-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_998824.1|refseq:NP_998825.1|dip:DIP-442N|ensembl:ENSMUSG00000004040(gene)|ensembl:ENSMUST00000127638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|mint:P42227|rcsb pdb:1BG1|rcsb pdb:3CWG|rcsb pdb:4E68|rcsb pdb:4ZIA|reactome:R-MMU-1059683|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6783783|reactome:R-MMU-6785807|reactome:R-MMU-8849474|reactome:R-MMU-8854691|reactome:R-MMU-8875791|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9008059|reactome:R-MMU-9020933|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-8983432 - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:jWu9RTbZkTUtGrXQlg1K79zHowM10090 intact-crc:3C849F9A5C1E946A false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000026072 uniprotkb:P51450 intact:EBI-6398437 intact:EBI-4422044|uniprotkb:E9Q8I1|uniprotkb:Q3U513|uniprotkb:Q61027|uniprotkb:Q91YT5|uniprotkb:Q9QXD9|uniprotkb:Q9R177 psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:rorg_mouse(display_long)|uniprotkb:Rorc(gene name)|psi-mi:Rorc(display_short)|uniprotkb:Nr1f3(gene name synonym)|uniprotkb:Rorg(gene name synonym)|uniprotkb:Thor(gene name synonym)|uniprotkb:Nuclear receptor RZR-gamma(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group F member 3(gene name synonym)|uniprotkb:Retinoid-related orphan receptor-gamma(gene name synonym)|uniprotkb:Thymus orphan receptor(gene name synonym)|uniprotkb:RAR-related orphan receptor C(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398578|imex:IM-18126-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_001280663.1|refseq:NP_035411.2|reactome:R-MMU-383280|dip:DIP-59439N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019218"(regulation of steroid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036315"(cellular response to sterol)|go:"GO:0042093"(T-helper cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048535"(lymph node development)|go:"GO:0048537"(mucosa-associated lymphoid tissue development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0098531"(ligand-activated transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003079(Nuclear receptor ROR)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR044101 - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 - rogid:UN/SJWwC1Jl05UgqUvGdYMPJLas10090 intact-crc:C427B213435BE8A7 false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P42227 ensembl:ENSMUSG00000000791 intact:EBI-602878|uniprotkb:A2A5D1|uniprotkb:B7ZC17|ensembl:ENSMUSP00000120152 intact:EBI-6398451 psi-mi:stat3_mouse(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:Stat3(gene name)|psi-mi:Stat3(display_short)|uniprotkb:Aprf(gene name synonym) psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398771|imex:IM-18126-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_998824.1|refseq:NP_998825.1|dip:DIP-442N|ensembl:ENSMUSG00000004040(gene)|ensembl:ENSMUST00000127638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|mint:P42227|rcsb pdb:1BG1|rcsb pdb:3CWG|rcsb pdb:4E68|rcsb pdb:4ZIA|reactome:R-MMU-1059683|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6783783|reactome:R-MMU-6785807|reactome:R-MMU-8849474|reactome:R-MMU-8854691|reactome:R-MMU-8875791|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9008059|reactome:R-MMU-9020933|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-8983432 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:jWu9RTbZkTUtGrXQlg1K79zHowM10090 - intact-crc:6996F3F6F3A671F6 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P42227 ensembl:ENSMUSG00000041872 intact:EBI-602878|uniprotkb:A2A5D1|uniprotkb:B7ZC17|ensembl:ENSMUSP00000120152 intact:EBI-6398447 psi-mi:stat3_mouse(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:Stat3(gene name)|psi-mi:Stat3(display_short)|uniprotkb:Aprf(gene name synonym) psi-mi:il17f_mouse_gene(display_short)|psi-mi:ENSMUSG00000041872(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398723|imex:IM-18126-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_998824.1|refseq:NP_998825.1|dip:DIP-442N|ensembl:ENSMUSG00000004040(gene)|ensembl:ENSMUST00000127638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|mint:P42227|rcsb pdb:1BG1|rcsb pdb:3CWG|rcsb pdb:4E68|rcsb pdb:4ZIA|reactome:R-MMU-1059683|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6783783|reactome:R-MMU-6785807|reactome:R-MMU-8849474|reactome:R-MMU-8854691|reactome:R-MMU-8875791|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9008059|reactome:R-MMU-9020933|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-8983432 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:jWu9RTbZkTUtGrXQlg1K79zHowM10090 - intact-crc:DD70DCF4E52F2563 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q61164 ensembl:ENSMUSG00000025929 intact:EBI-932785|ensembl:ENSMUSP00000005841 intact:EBI-4566324 psi-mi:ctcf_mouse(display_long)|uniprotkb:Ctcf(gene name)|psi-mi:Ctcf(display_short)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym) psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398705|imex:IM-18126-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_851839.1|refseq:XP_006530711.1|dip:DIP-38020N|ensembl:ENSMUSG00000005698(gene)|ensembl:ENSMUST00000005841(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61164|reactome:R-MMU-212436 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:r9BpKoiLzrCAiQttYFbIIkitePk10090 - intact-crc:8F3C9C531C0A7AA8 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 uniprotkb:Q64287 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398840|imex:IM-18126-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - figure legend:Supp Fig. 2B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 intact-crc:7E3B832B8F1359F9 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000027718 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398831 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:il21_mouse_gene(display_short)|psi-mi:ENSMUSG00000027718(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398840|imex:IM-18126-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Supp Fig. 2B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:7E3B832B8F1359F9 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 uniprotkb:O35284 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398826|imex:IM-18126-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - figure legend:Fig. 2E|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 intact-crc:0D39E94066EC5218 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000026012 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398822 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:cd28_mouse_gene(display_short)|psi-mi:ENSMUSG00000026012(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398826|imex:IM-18126-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Fig. 2E|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:0D39E94066EC5218 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000016529 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398833 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:il10_mouse_gene(display_short)|psi-mi:ENSMUSG00000016529(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398845|imex:IM-18126-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Supp Fig. 2B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:41D8581000E4AE6B false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 uniprotkb:O35284 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398845|imex:IM-18126-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - figure legend:Supp Fig. 2B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 intact-crc:41D8581000E4AE6B false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000026012 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398822 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:cd28_mouse_gene(display_short)|psi-mi:ENSMUSG00000026012(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398819|imex:IM-18126-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Fig. 2E|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:D235EB0BB26F9639 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 uniprotkb:Q64287 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398819|imex:IM-18126-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - figure legend:Fig. 2E|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 intact-crc:D235EB0BB26F9639 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 uniprotkb:O35284 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398835|imex:IM-18126-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - figure legend:Supp Fig. 2B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 intact-crc:1DC29949787C55FB false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000027718 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398831 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:il21_mouse_gene(display_short)|psi-mi:ENSMUSG00000027718(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398835|imex:IM-18126-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Supp Fig. 2B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:1DC29949787C55FB false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 uniprotkb:Q64287 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398850|imex:IM-18126-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - figure legend:Supp Fig. 2B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 intact-crc:22214272F78BA269 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000016529 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398833 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:il10_mouse_gene(display_short)|psi-mi:ENSMUSG00000016529(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398850|imex:IM-18126-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Supp Fig. 2B|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:22214272F78BA269 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000025929 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-4566324 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398657|imex:IM-18126-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th0)|taxid:10090(Mouse naive Th0 cell) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:769EEE2E76F8415F false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000028150 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-4422030 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398609|imex:IM-18126-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th0)|taxid:10090(Mouse naive Th0 cell) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:6066B74246579807 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000025929 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-4566324 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:il17_mouse_gene(display_short)|psi-mi:ENSMUSG00000025929(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398663|imex:IM-18126-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th0)|taxid:10090(Mouse naive Th0 cell) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:B07F648FDF8A5E13 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) ensembl:ENSMUSG00000028150 uniprotkb:Q64287 intact:EBI-4422030 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 psi-mi:rorg_mouse_gene(display_short)|psi-mi:ENSMUSG00000028150(display_long) psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398603|imex:IM-18126-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th0)|taxid:10090(Mouse naive Th0 cell) - 2012/11/27 2014/10/16 - rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 intact-crc:59058E0707C196BD false binding-associated region:?-? - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000000791 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398451 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398759|imex:IM-18126-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th0)|taxid:10090(Mouse naive Th0 cell) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:309A9E92C8FD9C51 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000026072 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398437 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398552|imex:IM-18126-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th0)|taxid:10090(Mouse naive Th0 cell) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:02A4C00707C124D7 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 ensembl:ENSMUSG00000026072 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398437 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:il1r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000026072(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398550|imex:IM-18126-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 - - - - figure legend:Supp Fig. 1D|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th0)|taxid:10090(Mouse naive Th0 cell) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 - intact-crc:EDF6B275F047C55D false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64287 ensembl:ENSMUSG00000000791 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 intact:EBI-6398451 psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:i12r1_mouse_gene(display_short)|psi-mi:ENSMUSG00000000791(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398753|imex:IM-18126-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - - figure legend:Fig. 1A|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th0)|taxid:10090(Mouse naive Th0 cell) - 2012/11/27 2014/10/16 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 - intact-crc:24918D7878D5D953 false - binding-associated region:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35284 uniprotkb:Q64287 intact:EBI-6398523|ensembl:ENSMUSP00000040706|uniprotkb:A2RT86 intact:EBI-6398485|ensembl:ENSMUSP00000021784|uniprotkb:Q60802 psi-mi:batf_mouse(display_long)|uniprotkb:Batf(gene name)|psi-mi:Batf(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:irf4_mouse(display_long)|uniprotkb:Irf4(gene name)|psi-mi:Irf4(display_short)|uniprotkb:Spip(gene name synonym)|uniprotkb:Lymphocyte-specific interferon regulatory factor(gene name synonym)|uniprotkb:NF-EM5(gene name synonym)|uniprotkb:PU.1 interaction partner(gene name synonym)|uniprotkb:Transcriptional activator PIP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ciofani et al. (2012) pubmed:23021777|imex:IM-18126 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398815|imex:IM-18126-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034266(gene)|ensembl:ENSMUST00000040536(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|refseq:NP_058047.1 go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5BVI|ensembl:ENSMUSG00000021356(gene)|ensembl:ENSMUST00000021784(transcript)|go:"GO:0000786"(nucleosome)|refseq:NP_001334437.1|refseq:NP_038702.1|dip:DIP-59740N - - - figure legend:Fig. 2B|antagonist:EtBr|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-t-cell_th17)|taxid:10090(Mouse Thelper 17 cells) - 2012/11/27 2014/10/16 rogid:CbFq5UabNclS5zenzeDswvSEW5w10090 rogid:SQVoOKSlOxQYpoOhHowmFvknfgU10090 intact-crc:80EB6B80D21B04C2|rigid:8qytiVcRXGMrIRLvR2x/7qGsezo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)