#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P50150 uniprotkb:Q920B6 intact:EBI-6395970|ensembl:ENSP00000355556|ensembl:ENSP00000355557|ensembl:ENSP00000375727|ensembl:ENSP00000398629|ensembl:ENSP00000482192|ensembl:ENSP00000489027|ensembl:ENSP00000489194|ensembl:ENSP00000489228|ensembl:ENSP00000489307|ensembl:ENSP00000489454 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 psi-mi:gbg4_human(display_long)|uniprotkb:GNG4(gene name)|psi-mi:GNG4(display_short)|uniprotkb:GNGT4(gene name synonym) psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6396028|imex:IM-18125-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168243(gene)|ensembl:ENSG00000282972(gene)|ensembl:ENST00000366597(transcript)|ensembl:ENST00000366598(transcript)|ensembl:ENST00000391854(transcript)|ensembl:ENST00000450593(transcript)|ensembl:ENST00000484517(transcript)|ensembl:ENST00000634574(transcript)|ensembl:ENST00000635006(transcript)|ensembl:ENST00000635235(transcript)|ensembl:ENST00000635387(transcript)|ensembl:ENST00000635595(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|reactome:R-HSA-400042|refseq:XP_011542469.1|refseq:NP_001092191.1|refseq:NP_001092192.1|refseq:NP_004476.1|refseq:XP_006711824.1 ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 - - - figure legend:Fig. 3A, 3B, Supp. Fig. 5A, 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/11/21 2014/10/16 rogid:k3pcOkyPzniS0BCtCg25CbbbMOU9606 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 intact-crc:2127673A03B9E8BB|rigid:W+BDuBebg45cbveZCEscGx76Dfs false - mutation:39-39|sufficient binding region:17-27|sufficient binding region:28-39|sufficient binding region:51-61 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q920B6 uniprotkb:Q61016 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 intact:EBI-6398308|ensembl:ENSMUSP00000112409|ensembl:ENSMUSP00000113798|ensembl:ENSMUSP00000114003|uniprotkb:Q8JZP6 psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:gbg7_mouse(display_long)|uniprotkb:Gng7(gene name)|psi-mi:Gng7(display_short)|uniprotkb:Gngt7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398329|imex:IM-18125-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 ensembl:ENSMUSG00000048240(gene)|ensembl:ENSMUST00000117805(transcript)|ensembl:ENSMUST00000118233(transcript)|ensembl:ENSMUST00000118465(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007168"(receptor guanylyl cyclase signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272 - - - figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 rogid:JRVdci8TLD33EgvG1EMIFHh1v2E10090 intact-crc:FED76E9CD03BBB4F|rigid:JP2f36DZC51vEn6R1raML7cN618 false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P50153 uniprotkb:Q920B6 intact:EBI-6398258|ensembl:ENSMUSP00000021734 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 psi-mi:gbg4_mouse(display_long)|uniprotkb:Gng4(gene name)|psi-mi:Gng4(display_short)|uniprotkb:Gngt4(gene name synonym) psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398273|imex:IM-18125-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000021303(gene)|ensembl:ENSMUST00000021734(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|reactome:R-MMU-6814122|refseq:NP_001289926.1|refseq:NP_034447.1|dip:DIP-494N ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 - - - figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:WsTQFeMWRDJri2SIAsiVov1CtBc10090 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 intact-crc:14BBE012CAC88A3E|rigid:/Ki/vXhze83Op3NyPg0sO+/rYsg false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P63213 uniprotkb:Q920B6 intact:EBI-6396319|ensembl:ENSMUSP00000055256|ensembl:ENSMUSP00000124153|ensembl:ENSMUSP00000124725|ensembl:ENSMUSP00000125000|ensembl:ENSMUSP00000125141|ensembl:ENSMUSP00000125697|uniprotkb:P16874|uniprotkb:Q3TYE8|uniprotkb:Q61013|uniprotkb:Q9TS47 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 psi-mi:gbg2_mouse(display_long)|uniprotkb:Gng2(gene name)|psi-mi:Gng2(display_short)|uniprotkb:G gamma-I(gene name synonym) psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6396316|imex:IM-18125-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272837.1|refseq:NP_001272838.1|refseq:NP_001272839.1|refseq:NP_001272840.1|ensembl:ENSMUSG00000043004(gene)|ensembl:ENSMUST00000055100(transcript)|ensembl:ENSMUST00000159028(transcript)|ensembl:ENSMUST00000159073(transcript)|ensembl:ENSMUST00000160013(transcript)|ensembl:ENSMUST00000161247(transcript)|ensembl:ENSMUST00000162425(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008283"(cell population proliferation)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|rcsb pdb:6RMV|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|refseq:NP_001033726.1|refseq:NP_034445.1|ensembl:ENSMUSG00000043004|ensembl:ENSMUSG00000043004 ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 - - - figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:8asTjDtSU6sCPSMwcXMbV340Rt410090 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 intact-crc:9865F837EE5883F5|rigid:5YloDxuDT1g6Xloc0RO/3pGa7fw false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P63216 uniprotkb:Q920B6 intact:EBI-6396350|ensembl:ENSMUSP00000093978|uniprotkb:P29798|uniprotkb:Q61014 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 psi-mi:gbg3_mouse(display_long)|uniprotkb:Gng3(gene name)|psi-mi:Gng3(display_short)|uniprotkb:Gngt3(gene name synonym) psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6396367|imex:IM-18125-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000071658(gene)|ensembl:ENSMUST00000096259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0044297"(cell body)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|refseq:NP_034446.1 ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 - - - figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:12BoRqNsIdIteDqd8gtN1bCXTJc10090 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 intact-crc:C5FBD4861B3D2231|rigid:gLN5/NyurHeQ3pXkpjE8t9IvuLk false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P50150 uniprotkb:Q920B6 intact:EBI-6395970|ensembl:ENSP00000355556|ensembl:ENSP00000355557|ensembl:ENSP00000375727|ensembl:ENSP00000398629|ensembl:ENSP00000482192|ensembl:ENSP00000489027|ensembl:ENSP00000489194|ensembl:ENSP00000489228|ensembl:ENSP00000489307|ensembl:ENSP00000489454 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 psi-mi:gbg4_human(display_long)|uniprotkb:GNG4(gene name)|psi-mi:GNG4(display_short)|uniprotkb:GNGT4(gene name synonym) psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6396150|imex:IM-18125-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168243(gene)|ensembl:ENSG00000282972(gene)|ensembl:ENST00000366597(transcript)|ensembl:ENST00000366598(transcript)|ensembl:ENST00000391854(transcript)|ensembl:ENST00000450593(transcript)|ensembl:ENST00000484517(transcript)|ensembl:ENST00000634574(transcript)|ensembl:ENST00000635006(transcript)|ensembl:ENST00000635235(transcript)|ensembl:ENST00000635387(transcript)|ensembl:ENST00000635595(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|reactome:R-HSA-400042|refseq:XP_011542469.1|refseq:NP_001092191.1|refseq:NP_001092192.1|refseq:NP_004476.1|refseq:XP_006711824.1 ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 - - - figure legend:Fig. 3C, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:k3pcOkyPzniS0BCtCg25CbbbMOU9606 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 intact-crc:9A5F3E2BD731BD30|rigid:W+BDuBebg45cbveZCEscGx76Dfs false green fluorescent protein tag:?-?|sufficient binding region:32-75 ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q920B6 uniprotkb:Q61012 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 intact:EBI-6396228|ensembl:ENSMUSP00000031673|uniprotkb:Q9CR01 psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:gbg1_mouse(display_long)|uniprotkb:Gngt1(gene name)|psi-mi:Gngt1(display_short)|uniprotkb:Gng1(gene name synonym)|uniprotkb:Transducin gamma chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6396225|imex:IM-18125-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 ensembl:ENSMUSG00000029663(gene)|ensembl:ENSMUST00000031673(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008104"(protein localization)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-2485179|reactome:R-MMU-2514859|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|reactome:R-MMU-381676|refseq:XP_006505049.1|refseq:NP_034444.1|refseq:XP_017176877.1|refseq:XP_017176878.1 - - - figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 rogid:dUA8/uCvfOs4765PI0ajTN4Gyd410090 intact-crc:FED61D6135FBBB4F|rigid:LFb7g7GGfXlTjGISmIYxTLDZ0GI false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9JMF3 uniprotkb:Q920B6 intact:EBI-6398376|ensembl:ENSMUSP00000110760|ensembl:ENSMUSP00000131648 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 psi-mi:gbg13_mouse(display_long)|uniprotkb:Gng13(gene name)|psi-mi:Gng13(display_short) psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398389|imex:IM-18125-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000025739(gene)|ensembl:ENSMUST00000115108(transcript)|ensembl:ENSMUST00000172002(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0050909"(sensory perception of taste)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|interpro:IPR039227|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-381753|reactome:R-MMU-381771|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|refseq:XP_006524842.1|refseq:NP_071867.1|dip:DIP-46321N ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 - - - figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:lZ3Ve3WWSO64opWwp3Qf9WorJMs10090 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 intact-crc:0C0952E9B10FD5F3|rigid:IDlc1VVfAspoVuIOhicEFVrVPmo false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q920B6 uniprotkb:P63078 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 intact:EBI-6398338|ensembl:ENSMUSP00000077314|ensembl:ENSMUSP00000145533|ensembl:ENSMUSP00000145567|uniprotkb:P43426 psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:gbg8_mouse(display_long)|uniprotkb:Gng8(gene name)|psi-mi:Gng8(display_short)|uniprotkb:Gng9(gene name synonym)|uniprotkb:Gngt9(gene name synonym)|uniprotkb:Gamma-9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398355|imex:IM-18125-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 refseq:XP_011248738.1|ensembl:ENSMUSG00000063594(gene)|ensembl:ENSMUST00000078182(transcript)|ensembl:ENSMUST00000205459(transcript)|ensembl:ENSMUST00000205716(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0035176"(social behavior)|go:"GO:0043584"(nose development)|go:"GO:0071444"(cellular response to pheromone)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|interpro:IPR036284|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|refseq:XP_006539610.1|refseq:XP_006539611.1|refseq:XP_006539612.1|refseq:NP_034450.1 - - - figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 rogid:t1QFHM4H71LGdkwuyURoCYtT6rU10090 intact-crc:809D1B1F53613B15|rigid:FJyH83lbX9atxiVfjD2tYB34Cio false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9DAS9 uniprotkb:Q920B6 intact:EBI-1183804|uniprotkb:Q544P3|ensembl:ENSMUSP00000046557|ensembl:ENSMUSP00000109860|ensembl:ENSMUSP00000109862|ensembl:ENSMUSP00000109863|ensembl:ENSMUSP00000109864|ensembl:ENSMUSP00000109865|ensembl:ENSMUSP00000109866 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 psi-mi:gbg12_mouse(display_long)|uniprotkb:Gng12(gene name)|psi-mi:Gng12(display_short) psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6398364|imex:IM-18125-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171027.1|refseq:NP_001171028.1|refseq:NP_001171029.1|refseq:NP_001171030.1|refseq:NP_001171031.1|refseq:NP_079554.1|ensembl:ENSMUSG00000036402(gene)|ensembl:ENSMUST00000043148(transcript)|ensembl:ENSMUST00000114222(transcript)|ensembl:ENSMUST00000114224(transcript)|ensembl:ENSMUST00000114225(transcript)|ensembl:ENSMUST00000114226(transcript)|ensembl:ENSMUST00000114227(transcript)|ensembl:ENSMUST00000114228(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0042301"(phosphate ion binding)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|refseq:XP_006505605.1 ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 - - - figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/11/21 2014/10/16 rogid:29C/KggTANGedW9+lPzudGdahYk10090 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 intact-crc:E20B080FEA4FB36F|rigid:1Q0QAChIWII42N8znVzYuUmzg7o false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q920B6 uniprotkb:P50150 intact:EBI-6530063|ensembl:ENSRNOP00000003684|uniprotkb:A3QR52|uniprotkb:Q3MMY3|uniprotkb:Q5DNW4|uniprotkb:Q5DNW5 intact:EBI-6395970|ensembl:ENSP00000355556|ensembl:ENSP00000355557|ensembl:ENSP00000375727|ensembl:ENSP00000398629|ensembl:ENSP00000482192|ensembl:ENSP00000489027|ensembl:ENSP00000489194|ensembl:ENSP00000489228|ensembl:ENSP00000489307|ensembl:ENSP00000489454 psi-mi:kcnk2_rat(display_long)|uniprotkb:Kcnk2(gene name)|psi-mi:Kcnk2(display_short)|uniprotkb:Two pore potassium channel TPKC1(gene name synonym)|uniprotkb:Outward rectifying potassium channel protein TREK-1(gene name synonym)|uniprotkb:Stretch-activated potassium channel TREK-1(gene name synonym)|uniprotkb:"TREK-1 K(+) channel subunit"(gene name synonym)|uniprotkb:Trek(gene name synonym)|uniprotkb:Two pore domain potassium channel TREK-1(gene name synonym) psi-mi:gbg4_human(display_long)|uniprotkb:GNG4(gene name)|psi-mi:GNG4(display_short)|uniprotkb:GNGT4(gene name synonym) psi-mi:"MI:0096"(pull down) Woo et al. (2012) pubmed:23021213|imex:IM-18125 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6396200|imex:IM-18125-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000002653(gene)|ensembl:ENSRNOT00000003684(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007613"(memory)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0030424"(axon)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0048678"(response to axon injury)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|go:"GO:0097449"(astrocyte projection)|go:"GO:1900039"(positive regulation of cellular response to hypoxia)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR003976(Potassium channel, two pore-domain, TREK)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299503|reactome:R-RNO-5576886|go:"GO:0042391"(regulation of membrane potential)|refseq:NP_742039.1|rgd:621448|refseq:NP_742038.2|refseq:XP_006250495.1|refseq:XP_006250496.1 ensembl:ENSG00000168243(gene)|ensembl:ENSG00000282972(gene)|ensembl:ENST00000366597(transcript)|ensembl:ENST00000366598(transcript)|ensembl:ENST00000391854(transcript)|ensembl:ENST00000450593(transcript)|ensembl:ENST00000484517(transcript)|ensembl:ENST00000634574(transcript)|ensembl:ENST00000635006(transcript)|ensembl:ENST00000635235(transcript)|ensembl:ENST00000635387(transcript)|ensembl:ENST00000635595(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|reactome:R-HSA-400042|refseq:XP_011542469.1|refseq:NP_001092191.1|refseq:NP_001092192.1|refseq:NP_004476.1|refseq:XP_006711824.1 - - - figure legend:Supp. Fig. 5A, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/11/21 2014/10/16 rogid:2yHN0/6Vw20iYSjohg1sTp847Y810116 rogid:k3pcOkyPzniS0BCtCg25CbbbMOU9606 intact-crc:4730EF0F4196EF2B|rigid:W+BDuBebg45cbveZCEscGx76Dfs false sufficient binding region:17-27|sufficient binding region:28-39|mutation:39-39|sufficient binding region:51-61 maltose binding protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)