#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P27467	uniprotkb:Q9Y5W5	intact:EBI-2899665|ensembl:ENSMUSP00000010044	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058045|mint:MINT-8389803	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N|mint:MINT-8389806(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389808(identity)	-	-	-	comment:mint|figure legend:t1	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.0x10^-9(molar)	2012/07/30	2014/10/16	rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:52950DDE61294E1A|rigid:2zpq1mfSVXGfsZfL3R6emxWH6Ak	false	-	binding-associated region:32-181(MINT-8389809)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22725	uniprotkb:Q9Y5W5	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058030|mint:MINT-8389733	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N|mint:MINT-8389735(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389736(identity)	-	-	-	comment:homomint|comment:mint|figure legend:t1 f1 f2	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:7.8x10^-10(molar)	2012/07/30	2014/10/16	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:A6C994D68992C568|rigid:VPv+LPWvE7oiO0z3A/7gH/uBQVc	false	-	binding-associated region:32-181(MINT-8389798)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00755	uniprotkb:Q9Y5W5	intact:EBI-727198|uniprotkb:Q9Y560|uniprotkb:Q96H90|ensembl:ENSP00000285018	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt7a_human(display_long)|uniprotkb:WNT7A(gene name)|psi-mi:WNT7A(display_short)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058091|mint:MINT-8389828	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004616.2|ensembl:ENSG00000154764(gene)|ensembl:ENST00000285018(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001525"(angiogenesis)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045165"(cell fate commitment)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0062009"(secondary palate development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048864"(stem cell development)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060054"(positive regulation of epithelial cell proliferation involved in wound healing)|go:"GO:0060066"(oviduct development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099068"(postsynapse assembly)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905386"(positive regulation of protein localization to presynapse)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013300(Wnt-7 protein)|interpro:IPR018161|interpro:IPR043158|rcsb pdb:4UZQ|reactome:R-HSA-3238698|reactome:R-HSA-373080|dip:DIP-61511N|mint:MINT-8389835(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389831(identity)	-	-	-	comment:homomint|comment:mint|figure legend:t1	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.9x10^-9(molar)	2012/07/30	2014/10/16	rogid:dydZ+HONRF0rd3v9Za9GTgBOlkU9606	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:B62C62106460C23F|rigid:5br8q83ZIGEjJLdmTJ4pdT3K38c	false	-	binding-associated region:32-181(MINT-8389832)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22724	uniprotkb:Q9Y5W5	intact:EBI-1570945|ensembl:ENSMUSP00000036580	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt4_mouse(display_long)|uniprotkb:Wnt4(gene name)|psi-mi:Wnt4(display_short)|uniprotkb:Wnt-4(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058076|mint:MINT-8389816	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033549.1|ensembl:ENSMUSG00000036856(gene)|ensembl:ENSMUST00000045747(transcript)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001823"(mesonephros development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0001889"(liver development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007276"(gamete generation)|go:"GO:0007548"(sex differentiation)|go:"GO:0008584"(male gonad development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032349"(positive regulation of aldosterone biosynthetic process)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033080"(immature T cell proliferation in thymus)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038030"(non-canonical Wnt signaling pathway via MAPK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048599"(oocyte development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060126"(somatotropin secreting cell differentiation)|go:"GO:0060129"(thyroid-stimulating hormone-secreting cell differentiation)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0061369"(negative regulation of testicular blood vessel morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072006"(nephron development)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0072034"(renal vesicle induction)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072174"(metanephric tubule formation)|go:"GO:0072210"(metanephric nephron development)|go:"GO:0072273"(metanephric nephron morphogenesis)|go:"GO:2000019"(negative regulation of male gonad development)|go:"GO:2000066"(positive regulation of cortisol biosynthetic process)|go:"GO:2000180"(negative regulation of androgen biosynthetic process)|go:"GO:2000225"(negative regulation of testosterone biosynthetic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009142(Wnt-4 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-3238698|reactome:R-MMU-4086400|go:"GO:0008585"(female gonad development)|mint:MINT-8389823(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389819(identity)	-	-	-	comment:homomint|comment:mint|figure legend:t1	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:2.2x10^-9(molar)	2012/07/30	2014/10/16	rogid:Mqq6P+QzlTQmFiPhRQdQeqzzS/U10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:2BB3B1A431D0592F|rigid:5UIgPmYlhg4Fqk46A9Hbtj7uE4E	false	-	binding-associated region:32-181(MINT-8389820)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O35468	uniprotkb:Q9Y5W5	intact:EBI-8058106|intact:MINT-8389631|uniprotkb:Q8VI90|ensembl:ENSMUSP00000018630	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt9b_mouse(display_long)|uniprotkb:Wnt9b(gene name)|psi-mi:Wnt9b(display_short)|uniprotkb:Wnt14b(gene name synonym)|uniprotkb:Wnt15(gene name synonym)|uniprotkb:Protein Wnt-14b(gene name synonym)|uniprotkb:Protein Wnt-15(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058146|mint:MINT-8389840	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035849.3|dip:DIP-59409N|ensembl:ENSMUSG00000018486(gene)|ensembl:ENSMUST00000018630(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003339"(regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030539"(male genitalia development)|go:"GO:0035150"(regulation of tube size)|go:"GO:0039706"(co-receptor binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0072003"(kidney rudiment formation)|go:"GO:0072038"(mesenchymal stem cell maintenance involved in nephron morphogenesis)|go:"GO:0072044"(collecting duct development)|go:"GO:0072046"(establishment of planar polarity involved in nephron morphogenesis)|go:"GO:0072078"(nephron tubule morphogenesis)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072170"(metanephric tubule development)|go:"GO:0072174"(metanephric tubule formation)|go:"GO:0072181"(mesonephric duct formation)|go:"GO:1902455"(negative regulation of stem cell population maintenance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1905438"(non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026535|interpro:IPR043158|reactome:R-MMU-3238698|mint:MINT-8389847(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389843(identity)	-	comment:mint	-	comment:mint|figure legend:t1	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.3x10^-9(molar)	2012/07/30	2014/10/16	rogid:m1lTuVMR2z9FIUH8IgKkvmPVDyU10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:50D6934983107073|rigid:gs7gQJXOU7KoqFyYrecVc6QI1zY	false	-	binding-associated region:32-181(MINT-8389844)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O96014	uniprotkb:Q9Y5W5	intact:EBI-8058160|uniprotkb:Q14DE8|uniprotkb:B2R8Z6|uniprotkb:Q8WZ98|intact:MINT-7003207|ensembl:ENSP00000325526	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt11_human(display_long)|uniprotkb:WNT11(gene name)|psi-mi:WNT11(display_short)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058220|mint:MINT-8389852	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005274288.1|refseq:NP_004617.2|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061101"(neuroendocrine cell differentiation)|go:"GO:0062009"(secondary palate development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090272"(negative regulation of fibroblast growth factor production)|interpro:IPR018161|interpro:IPR026536|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-4086398|reactome:R-HSA-4086400|interpro:IPR005817(Wnt superfamily)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030282"(bone mineralization)|ensembl:ENSG00000085741(gene)|ensembl:ENST00000322563(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003283"(atrial septum development)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032915"(positive regulation of transforming growth factor beta2 production)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060197"(cloacal septation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060675"(ureteric bud morphogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:MINT-8389859(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389855(identity)	-	comment:mint|comment:homomint|function:Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters	-	comment:homomint|comment:mint|figure legend:t1	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.6x10^-9(molar)	2012/07/30	2014/10/16	rogid:A6Em8CS+X3wsJKAj4GOVWny8Qxg9606	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:F57BB326CF3C33D4|rigid:lAGkLS7JPbQ3MTWdyUCvN64d7XY	false	-	binding-associated region:32-181(MINT-8389856)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y5W5	uniprotkb:P22725	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058298|mint:MINT-8389883	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389887(identity)	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N|mint:MINT-8389885(identity)	-	-	-	figure legend:t2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	intact-crc:F394052F0FB23542|rigid:VPv+LPWvE7oiO0z3A/7gH/uBQVc	false	binding-associated region:32-181(MINT-8389986)|mutation increasing interaction:15-15(MINT-8389888)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y5W5	uniprotkb:P22725	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058257|mint:MINT-8389868	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389871(identity)	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N|mint:MINT-8389870(identity)	-	-	-	figure legend:t2|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	intact-crc:E5B483C70045EA4D|rigid:VPv+LPWvE7oiO0z3A/7gH/uBQVc	false	mutation increasing interaction:13-13(MINT-8389876)|binding-associated region:32-181(MINT-8389983)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y5W5	uniprotkb:P22725	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058356|mint:MINT-8389894	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389898(identity)	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N|mint:MINT-8389896(identity)	-	-	-	comment:homomint|comment:mint|figure legend:t2 f2	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	intact-crc:4BD57B83D0189A09|rigid:VPv+LPWvE7oiO0z3A/7gH/uBQVc	false	binding-associated region:32-181(MINT-8389989)|mutation increasing interaction:32-32(MINT-8389899)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Y5W5	uniprotkb:P22725	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058376|mint:MINT-8389906	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389910(identity)	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N|mint:MINT-8389908(identity)	-	-	-	comment:homomint|comment:mint|figure legend:t2 f2	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	intact-crc:A8782141C653F719|rigid:VPv+LPWvE7oiO0z3A/7gH/uBQVc	false	mutation decreasing interaction:42-42(MINT-8389911)|binding-associated region:32-181(MINT-8389992)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22725	uniprotkb:Q9Y5W5	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058468|mint:MINT-8389930	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N|mint:MINT-8389932(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389934(identity)	-	-	-	comment:homomint|comment:mint|figure legend:t2	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:FD3C560D17680D6A|rigid:VPv+LPWvE7oiO0z3A/7gH/uBQVc	false	-	mutation decreasing interaction:25-25(MINT-8389935)|binding-associated region:32-181(MINT-8389998)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22725	uniprotkb:Q9Y5W5	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058416|mint:MINT-8389917	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N|mint:MINT-8389919(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389921(identity)	-	-	-	comment:homomint|comment:mint|figure legend:t2	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:523071892E6C2927|rigid:VPv+LPWvE7oiO0z3A/7gH/uBQVc	false	-	binding-associated region:32-181(MINT-8389995)|mutation decreasing interaction:27-27(MINT-8389922)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27467	uniprotkb:Q9Y5W5	intact:EBI-2899665|ensembl:ENSMUSP00000010044	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058537|mint:MINT-8389957	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N|mint:MINT-8389963(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389959(identity)	-	-	-	figure legend:t2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:947B4BB05CEADF90|rigid:2zpq1mfSVXGfsZfL3R6emxWH6Ak	false	-	binding-associated region:32-181(MINT-8390004)|mutation decreasing interaction:15-15(MINT-8389960)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27467	uniprotkb:Q9Y5W5	intact:EBI-2899665|ensembl:ENSMUSP00000010044	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058487|mint:MINT-8389944	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N|mint:MINT-8389946(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389948(identity)	-	-	-	figure legend:t2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:9978F2E393D740D8|rigid:2zpq1mfSVXGfsZfL3R6emxWH6Ak	false	-	mutation decreasing interaction:13-13(MINT-8389949)|binding-associated region:32-181(MINT-8390001)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27467	uniprotkb:Q9Y5W5	intact:EBI-2899665|ensembl:ENSMUSP00000010044	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058621|mint:MINT-8390007	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N|mint:MINT-8390013(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8390009(identity)	-	-	-	figure legend:t2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:E8435D5DB019CB98|rigid:2zpq1mfSVXGfsZfL3R6emxWH6Ak	false	-	mutation decreasing interaction:27-27(MINT-8390010)|binding-associated region:32-181(MINT-8390049)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27467	uniprotkb:Q9Y5W5	intact:EBI-2899665|ensembl:ENSMUSP00000010044	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058587|mint:MINT-8389973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N|mint:MINT-8389979(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8389975(identity)	-	-	-	figure legend:t2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:7CBDCA6CF50D415F|rigid:2zpq1mfSVXGfsZfL3R6emxWH6Ak	false	-	mutation decreasing interaction:25-25(MINT-8389976)|binding-associated region:32-181(MINT-8390046)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27467	uniprotkb:Q9Y5W5	intact:EBI-2899665|ensembl:ENSMUSP00000010044	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058671|mint:MINT-8390017	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N|mint:MINT-8390023(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8390019(identity)	-	-	-	figure legend:t2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:BB8347EC00181131|rigid:2zpq1mfSVXGfsZfL3R6emxWH6Ak	false	-	mutation decreasing interaction:32-32(MINT-8390020)|binding-associated region:32-181(MINT-8390052)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27467	uniprotkb:Q9Y5W5	intact:EBI-2899665|ensembl:ENSMUSP00000010044	intact:EBI-3922719|uniprotkb:Q8WVG4|uniprotkb:Q6UXI1|ensembl:ENSP00000286574	psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym)	psi-mi:wif1_human(display_long)|uniprotkb:WIF1(gene name)|psi-mi:WIF1(display_short)|uniprotkb:UNQ191/PRO217(orf name)	psi-mi:"MI:0405"(competition binding)	Bányai et al. (2012)	pubmed:22986341|mint:MINT-8389626	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8058711|mint:MINT-8390027	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N|mint:MINT-8390033(identity)	dip:DIP-59097N|refseq:NP_009122.2|ensembl:ENSG00000156076(gene)|ensembl:ENST00000286574(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003306(WIF domain)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013309("Wnt inhibitory factor (WIF)-1")|interpro:IPR038677|rcsb pdb:2D3J|rcsb pdb:2YGN|rcsb pdb:2YGO|rcsb pdb:2YGP|rcsb pdb:2YGQ|reactome:R-HSA-201681|reactome:R-HSA-3772470|mint:MINT-8390029(identity)	-	-	-	figure legend:t2|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090	rogid:19NePdPffERDUhuJlk1Wg4OHKVc9606	intact-crc:824C3B1ECB75A6EB|rigid:2zpq1mfSVXGfsZfL3R6emxWH6Ak	false	-	binding-associated region:32-181(MINT-8390055)|mutation decreasing interaction:42-42(MINT-8390030)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)